CircNet

General Information

circRNA Basic Information

CircID	chr12:21882766\|21917103
Strand	-
CircType	exon
Host Gene	ENSG00000069431.11;
Algorism	find_circ;CIRI2;DCC;
Sequence	CCCTGTTCCTGTATTGGGTAATGGCCTTTATTACAAAAACAATAAAATTGGTTAAGTACTGTCAGTCTGGCTTGGACATATCAAACCTGCGTTTCTGCATCACAGGCATGATGGTCATCTTGAATGGGCTCTTGATGGCTGTGGAGATCAATGTCATTCGAGTCAGGAGATATGTATTTTTCATGAATCCTCAGAAAGTAAAGCCTCCTGAAGACCTCCAGGATCTGGGAGTGAGATTTCTTCAACCATTTGTGAATTTGCTGTCAAAAGCAACATACTGGTGGATGAACACACTTATTATATCTGCTCACAAAAAGCCTATTGATCTGAAGGCAATTGGAAAATTGCCAATAGCAATGAGAGCAGTAACAAATTATGTTTGCCTGAAAGATGCATATGAAGAACAAAAGAAAAAAGTTGCAGATCATCCAAATCGGACTCCATCTATATGGCTTGCAATGTACAGAGCTTTTGGGCGACCAATTCTACTTAGTAGCACATTCCGCTATCTGGCTGATTTACTGGGTTTTGCTGGACCTCTTTGTATTTCTGGAATAGTTCAGCGTGTGAATGAAACCCAGAATGGGACAAATAACACAACTGGAATTTCAGAAACCCTCTCATCAAAGGAATTTCTTGAAAACGCTTACGTTCTAGCAGTTCTTCTCTTCTTGGCTCTTATTCTGCAAAGGACATTTTTGCAGGCTTCCTACTATGTAACCATAGAGACTGGCATTAACCTCCGTGGAGCTCTGCTGGCCATGATTTATAATAAAATCCTTAGGCTCTCTACGTCTAACTTATCCATGGGGGAGATGACTCTGGGGCAGATCAACAACTTAGTCGCCATTGAAACTAATCAACTCATGTGGTTTTTGTTCCTGTGTCCCAATCTATGGGCTATGCCTGTTCAGATCATAATGGGCGTGATTCTGCTCTATAATTTACTTGGATCAAGTGCATTGGTCGGTGCAGCTGTCATTGTGCTCCTTGCGCCAATTCAGTACTTTATTGCTACAAAGTTGGCAGAGGCTCAGAAAAGTACACTTGATTATTCCACTGAGAGACTCAAGAAAACAAATGAAATATTGAAAGGCATCAAACTTCTAAAATTGTATGCCTGGGAACACATTTTCTGCAAAAGTGTGGAGGAAACAAGAATGAAAGAACTATCTAGTCTCAAAACCTTTGCACTATATACATCACTCTCCATCTTCATGAATGCAGCAATTCCCATAGCAGCTGTTCTTGCTACATTTGTGACCCATGCGTATGCCAGTGGAAACAATCTGAAACCTGCAGAGGCCTTTGCTTCACTGTCTCTCTTCCATATCCTGGTCACACCACTGTTCCTGCTCTCCACGGTGGTCAGATTTGCAGTCAAAGCCATCATAAGTCTGTGTTTATTGTTTTTTGCAGTGTTCAAAAGCTGAATGAGTTTCTCTTGAGTGATGAGATTGGTGACGACAGTTGGCGAACTGGTGAAAGTTCGCTTCCTTTTGAGTCCTGTAAGAAGCACACTGGAGTTCAGCCAAAAACTATAAACAGGAAACAGCCTGGAAGATATCACCTGGACAGCTATGAGCAATCAACACGGCGTCTACGTCCCGCAGAAACAGAGGACATTGCAATAAAG

circRNA Expression in different cancers

circRNA-miRNA-gene regulatory network

Target miRNAs

CircID	miRNA	PITA	miRanda	targetScan
chr12:21882766\|21917103	hsa-miR-298	1	1	1
chr12:21882766\|21917103	hsa-miR-760	1	1	1
chr12:21882766\|21917103	hsa-miR-4437	1	1	1
chr12:21882766\|21917103	hsa-miR-4449	1	1	1
chr12:21882766\|21917103	hsa-miR-3135b	1	1	1
chr12:21882766\|21917103	hsa-miR-26b-3p	1	1	1
chr12:21882766\|21917103	hsa-miR-1287-5p	1	1	1
chr12:21882766\|21917103	hsa-miR-215-3p	1	1	1
chr12:21882766\|21917103	hsa-miR-6861-5p	1	1	1
chr12:21882766\|21917103	hsa-miR-6894-5p	1	1	1
chr12:21882766\|21917103	hsa-miR-4768-3p	1	1	1
chr12:21882766\|21917103	hsa-miR-7847-3p	1	1	1
chr12:21882766\|21917103	hsa-miR-6730-5p	1	1	1
chr12:21882766\|21917103	hsa-miR-4459	1	1	1
chr12:21882766\|21917103	hsa-miR-6721-5p	1	1	1
chr12:21882766\|21917103	hsa-miR-8069	1	1	1
chr12:21882766\|21917103	hsa-miR-432-5p	1	1	1
chr12:21882766\|21917103	hsa-miR-1273g-5p	1	1	1
chr12:21882766\|21917103	hsa-miR-2467-3p	1	1	1
chr12:21882766\|21917103	hsa-miR-6888-5p	1	1	1
chr12:21882766\|21917103	hsa-miR-3934-3p	1	1	1
chr12:21882766\|21917103	hsa-miR-5004-3p	1	1	1
chr12:21882766\|21917103	hsa-miR-619-3p	1	1	1
chr12:21882766\|21917103	hsa-miR-1228-5p	1	1	1
chr12:21882766\|21917103	hsa-miR-4638-3p	1	1	1
chr12:21882766\|21917103	hsa-miR-937-5p	1	1	1
chr12:21882766\|21917103	hsa-miR-3190-5p	1	1	1
chr12:21882766\|21917103	hsa-miR-3681-5p	1	1	1
chr12:21882766\|21917103	hsa-miR-3140-3p	1	1	1
chr12:21882766\|21917103	hsa-miR-130b-5p	1	1	1

Target Genes

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Target miRNA Expression in different cancers

circRNA Open Reading Frame (ORF)

CircID	chr12:21882766\|21917103
ORF Type	ORF1
Protein Length	471
Nucleotide Length	1413
Protein Sequence	MAFITKTIKLVKYCQSGLDISNLRFCITGMMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHKKPIDLKAIGKLPIAMRAVTNYVCLKDAYEEQKKKVADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNETQNGTNNTTGISETLSSKEFLENAYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISLCLLFFAVFKS*
Nucleotide Sequence	ATGGCCTTTATTACAAAAACAATAAAATTGGTTAAGTACTGTCAGTCTGGCTTGGACATATCAAACCTGCGTTTCTGCATCACAGGCATGATGGTCATCTTGAATGGGCTCTTGATGGCTGTGGAGATCAATGTCATTCGAGTCAGGAGATATGTATTTTTCATGAATCCTCAGAAAGTAAAGCCTCCTGAAGACCTCCAGGATCTGGGAGTGAGATTTCTTCAACCATTTGTGAATTTGCTGTCAAAAGCAACATACTGGTGGATGAACACACTTATTATATCTGCTCACAAAAAGCCTATTGATCTGAAGGCAATTGGAAAATTGCCAATAGCAATGAGAGCAGTAACAAATTATGTTTGCCTGAAAGATGCATATGAAGAACAAAAGAAAAAAGTTGCAGATCATCCAAATCGGACTCCATCTATATGGCTTGCAATGTACAGAGCTTTTGGGCGACCAATTCTACTTAGTAGCACATTCCGCTATCTGGCTGATTTACTGGGTTTTGCTGGACCTCTTTGTATTTCTGGAATAGTTCAGCGTGTGAATGAAACCCAGAATGGGACAAATAACACAACTGGAATTTCAGAAACCCTCTCATCAAAGGAATTTCTTGAAAACGCTTACGTTCTAGCAGTTCTTCTCTTCTTGGCTCTTATTCTGCAAAGGACATTTTTGCAGGCTTCCTACTATGTAACCATAGAGACTGGCATTAACCTCCGTGGAGCTCTGCTGGCCATGATTTATAATAAAATCCTTAGGCTCTCTACGTCTAACTTATCCATGGGGGAGATGACTCTGGGGCAGATCAACAACTTAGTCGCCATTGAAACTAATCAACTCATGTGGTTTTTGTTCCTGTGTCCCAATCTATGGGCTATGCCTGTTCAGATCATAATGGGCGTGATTCTGCTCTATAATTTACTTGGATCAAGTGCATTGGTCGGTGCAGCTGTCATTGTGCTCCTTGCGCCAATTCAGTACTTTATTGCTACAAAGTTGGCAGAGGCTCAGAAAAGTACACTTGATTATTCCACTGAGAGACTCAAGAAAACAAATGAAATATTGAAAGGCATCAAACTTCTAAAATTGTATGCCTGGGAACACATTTTCTGCAAAAGTGTGGAGGAAACAAGAATGAAAGAACTATCTAGTCTCAAAACCTTTGCACTATATACATCACTCTCCATCTTCATGAATGCAGCAATTCCCATAGCAGCTGTTCTTGCTACATTTGTGACCCATGCGTATGCCAGTGGAAACAATCTGAAACCTGCAGAGGCCTTTGCTTCACTGTCTCTCTTCCATATCCTGGTCACACCACTGTTCCTGCTCTCCACGGTGGTCAGATTTGCAGTCAAAGCCATCATAAGTCTGTGTTTATTGTTTTTTGCAGTGTTCAAAAGCTGA

CircID	chr12:21882766\|21917103
ORF Type	ORF2
Protein Length	179
Nucleotide Length	537
Protein Sequence	LLIAVQVISSRLFPVYSFWLNSSVLLTGLKRKRTFTSSPTVVTNLITQEKLIQLLNTAKNNKHRLMMALTANLTTVESRNSGVTRIWKRDSEAKASAGFRLFPLAYAWVTNVARTAAMGIAAFMKMESDVYSAKVLRLDSSFILVSSTLLQKMCSQAYNFRSLMPFNISFVFLSLSVE*
Nucleotide Sequence	TTGCTCATAGCTGTCCAGGTGATATCTTCCAGGCTGTTTCCTGTTTATAGTTTTTGGCTGAACTCCAGTGTGCTTCTTACAGGACTCAAAAGGAAGCGAACTTTCACCAGTTCGCCAACTGTCGTCACCAATCTCATCACTCAAGAGAAACTCATTCAGCTTTTGAACACTGCAAAAAACAATAAACACAGACTTATGATGGCTTTGACTGCAAATCTGACCACCGTGGAGAGCAGGAACAGTGGTGTGACCAGGATATGGAAGAGAGACAGTGAAGCAAAGGCCTCTGCAGGTTTCAGATTGTTTCCACTGGCATACGCATGGGTCACAAATGTAGCAAGAACAGCTGCTATGGGAATTGCTGCATTCATGAAGATGGAGAGTGATGTATATAGTGCAAAGGTTTTGAGACTAGATAGTTCTTTCATTCTTGTTTCCTCCACACTTTTGCAGAAAATGTGTTCCCAGGCATACAATTTTAGAAGTTTGATGCCTTTCAATATTTCATTTGTTTTCTTGAGTCTCTCAGTGGAATAA

CircID	chr12:21882766\|21917103
ORF Type	ORF3
Protein Length	56
Nucleotide Length	168
Protein Sequence	MHMKNKRKKLQIIQIGLHLYGLQCTELLGDQFYLVAHSAIWLIYWVLLDLFVFLE*
Nucleotide Sequence	ATGCATATGAAGAACAAAAGAAAAAAGTTGCAGATCATCCAAATCGGACTCCATCTATATGGCTTGCAATGTACAGAGCTTTTGGGCGACCAATTCTACTTAGTAGCACATTCCGCTATCTGGCTGATTTACTGGGTTTTGCTGGACCTCTTTGTATTTCTGGAATAG

CircID	chr12:21882766\|21917103
ORF Type	ORF4
Protein Length	55
Nucleotide Length	165
Protein Sequence	MICNFFLLFFICIFQANIICYCSHCYWQFSNCLQINRLFVSRYNKCVHPPVCCF*
Nucleotide Sequence	ATGATCTGCAACTTTTTTCTTTTGTTCTTCATATGCATCTTTCAGGCAAACATAATTTGTTACTGCTCTCATTGCTATTGGCAATTTTCCAATTGCCTTCAGATCAATAGGCTTTTTGTGAGCAGATATAATAAGTGTGTTCATCCACCAGTATGTTGCTTTTGA

CircID	chr12:21882766\|21917103
ORF Type	ORF5
Protein Length	45
Nucleotide Length	135
Protein Sequence	MRGFLKFQLCYLSHSGFHSHAELFQKYKEVQQNPVNQPDSGMCY*
Nucleotide Sequence	ATGAGAGGGTTTCTGAAATTCCAGTTGTGTTATTTGTCCCATTCTGGGTTTCATTCACACGCTGAACTATTCCAGAAATACAAAGAGGTCCAGCAAAACCCAGTAAATCAGCCAGATAGCGGAATGTGCTACTAA

CircID	chr12:21882766\|21917103
ORF Type	ORF6
Protein Length	42
Nucleotide Length	126
Protein Sequence	MESDLDDLQLFSFVLHMHLSGKHNLLLLSLLLAIFQLPSDQ*
Nucleotide Sequence	ATGGAGTCCGATTTGGATGATCTGCAACTTTTTTCTTTTGTTCTTCATATGCATCTTTCAGGCAAACATAATTTGTTACTGCTCTCATTGCTATTGGCAATTTTCCAATTGCCTTCAGATCAATAG

CircID	chr12:21882766\|21917103
ORF Type	ORF7
Protein Length	41
Nucleotide Length	123
Protein Sequence	MKNTYLLTRMTLISTAIKSPFKMTIMPVMQKRRFDMSKPD*
Nucleotide Sequence	ATGAAAAATACATATCTCCTGACTCGAATGACATTGATCTCCACAGCCATCAAGAGCCCATTCAAGATGACCATCATGCCTGTGATGCAGAAACGCAGGTTTGATATGTCCAAGCCAGACTGA

CircID	chr12:21882766\|21917103
ORF Type	ORF8
Protein Length	32
Nucleotide Length	96
Protein Sequence	MLLLTANSQMVEEISLPDPGGLQEALLSEDS*
Nucleotide Sequence	ATGTTGCTTTTGACAGCAAATTCACAAATGGTTGAAGAAATCTCACTCCCAGATCCTGGAGGTCTTCAGGAGGCTTTACTTTCTGAGGATTCATGA

CircID	chr12:21882766\|21917103
ORF Type	ORF9
Protein Length	31
Nucleotide Length	93
Protein Sequence	MRLVTTVGELVKVRFLLSPVRSTLEFSQKL*
Nucleotide Sequence	ATGAGATTGGTGACGACAGTTGGCGAACTGGTGAAAGTTCGCTTCCTTTTGAGTCCTGTAAGAAGCACACTGGAGTTCAGCCAAAAACTATAA

CircID	chr12:21882766\|21917103
ORF Type	ORF10
Protein Length	79
Nucleotide Length	237
Protein Sequence	VFIVFCSVQKLNEFLLSDEIGDDSWRTGESSLPFESCKKHTGVQPKTINRKQPGRYHLDSYEQSTRRLRPAETEDIAIK
Nucleotide Sequence	GTGTTTATTGTTTTTTGCAGTGTTCAAAAGCTGAATGAGTTTCTCTTGAGTGATGAGATTGGTGACGACAGTTGGCGAACTGGTGAAAGTTCGCTTCCTTTTGAGTCCTGTAAGAAGCACACTGGAGTTCAGCCAAAAACTATAAACAGGAAACAGCCTGGAAGATATCACCTGGACAGCTATGAGCAATCAACACGGCGTCTACGTCCCGCAGAAACAGAGGACATTGCAATAAAG

CircID	chr12:21882766\|21917103
ORF Type	ORF11
Protein Length	55
Nucleotide Length	165
Protein Sequence	LKKSHSQILEVFRRLYFLRIHEKYISPDSNDIDLHSHQEPIQDDHHACDAETQV*
Nucleotide Sequence	TTGAAGAAATCTCACTCCCAGATCCTGGAGGTCTTCAGGAGGCTTTACTTTCTGAGGATTCATGAAAAATACATATCTCCTGACTCGAATGACATTGATCTCCACAGCCATCAAGAGCCCATTCAAGATGACCATCATGCCTGTGATGCAGAAACGCAGGTTTGA

CircID	chr12:21882766\|21917103
ORF Type	ORF12
Protein Length	52
Nucleotide Length	156
Protein Sequence	VLSVWLGHIKPAFLHHRHDGHLEWALDGCGDQCHSSQEICIFHESSESKAS*
Nucleotide Sequence	GTACTGTCAGTCTGGCTTGGACATATCAAACCTGCGTTTCTGCATCACAGGCATGATGGTCATCTTGAATGGGCTCTTGATGGCTGTGGAGATCAATGTCATTCGAGTCAGGAGATATGTATTTTTCATGAATCCTCAGAAAGTAAAGCCTCCTGA

CircID	chr12:21882766\|21917103
ORF Type	ORF13
Protein Length	51
Nucleotide Length	153
Protein Sequence	KFDAFQYFICFLESLSGIIKCTFLSLCQLCSNKVLNWRKEHNDSCTDQCT*
Nucleotide Sequence	AAGTTTGATGCCTTTCAATATTTCATTTGTTTTCTTGAGTCTCTCAGTGGAATAATCAAGTGTACTTTTCTGAGCCTCTGCCAACTTTGTAGCAATAAAGTACTGAATTGGCGCAAGGAGCACAATGACAGCTGCACCGACCAATGCACTTGA

RNA Binding Protein (RBP) of circRNA

CircID	RBP	Number of Upstream Sites	Number of Downstream Sites	Number of Circ Exons Sites
chr12:21882766\|21917103	RBM6	0	0	1
chr12:21882766\|21917103	TAF15	0	1	0
chr12:21882766\|21917103	ELAVL1	0	0	1
chr12:21882766\|21917103	CSTF2T	0	0	1
chr12:21882766\|21917103	WDR33	0	0	1
chr12:21882766\|21917103	FIP1L1	0	0	1
chr12:21882766\|21917103	FUS	1	2	1

CircRNA Information