CircNet

General Information

circRNA Basic Information

CircID	chr12:22517986\|22535344
Strand	-
CircType	exon
Host Gene	ENSG00000111731.12;
Algorism	find_circ;CIRI2;DCC;
Sequence	GTAAAATTTGGTAATACCACCTTTAAAACAGATGTGTACCTTAAGTCACTCAACCCTCAGTGGAACTCGGAGTGGTTTAAATTTGAGGTAAGTTTTTAAATGTCAGCATTTTTGAGTGTATTTTTTTGAGGTGACTCTTTTCCCTCAGGAATAATGAGAACCTTTTATTTCAGGCATAGTAGTATTTCTACATCACAAAAATATTTTCTTTTCTGCTTACCTAGGAATATTGAGTCTAAAAAAAGTTGTATTACATTTAAGAAAATACAGTATATGATAACACATTAACAAAAGAAGTCTTCAGATGTATTATATTATTATTATTGTAGTTTTCTCTAGATTTTAGCACATACCAAAAATTACTTAAGAATAATATATGGATTAAAATAAATTTTTAAAAATTGTAGTACTATATATTGTGAATATTGCCATTTAAATCATTTGTAAGTGTACAGTTTGGTAGCATTAATTACATTCACAGTGTTTTGCTACCATCACCGCTATTTCCAGAACTTTTTCTTTATCCTAAATGGAAATTGTGTACTCACTAACCAATAACTTCCCATTCCCTCCTCTCCCTAGACTCTGGTGACCTCTAATCTACTTTCTGTCTCTTTGAATTTGCTTATGCTAGATATGTGGATGATGAAGACTTACAAGATGAACCTTTACAGATCACAGTTCTTGACCATGATACTTACAGTGCAAATGATGCCATTGGTAAAGTGTACATTGATATTGATCCTTTACTGTATAGTGAAGCTGCAACAGTCATCTCAGGATGGTTTCCAATTTATGACACCATACATGGTATCCGTGGGGAAATCAATGTAGTTGTCAAAGTAGACCTCTTCAATGATTTAAATCGATTTAGGCAGTCATCATGTGGAGTCAAATTCTTTTGCACAACGTCTATTCCAAAATGCTATAGAGCTGTGATAATTCATGGATTTGTAGAAGAACTTGTGGTCAATGAAGACCCAGAATATCAGTGGATTGATCGAATTCGCACACCAAGGGCATCAAATGAGGCCAGACAGAGACTCATTTCGTTAATGTCAGGTGAGCTGCAGAGGAAGATTGGCTTGAAAGTACTTGAAATGAGAGGAAATGCAGTTGTGGGGTACTTACAGTGTTTCGATCTGGAGGGCGAGTCTGGGTTAGTGGTGCGAGCCATAGGAACGGCGTGTACTCTGGATAAATTAAGTAGCCCAGCAGCATTCCTTCCTGCATGTAATTCCCCATCCAAAGAAATGAAGGAGTCTCCGCTGGTTCATCCTCCAAGCCATGGATGCCGCTCGACTCACAACAGCCCAATTCACACTGCTACTGGCTCACGACTTACTCAGAACTTCTCTGTGTCTGTTCCCACTCTCATCTATACTGGTACGAGACTGCTCAGACTCCAGAGCTGGGGAGATGCAGGCCACGGGCAGAGTGGCTGCAGAGGCAGGCAGGCAGGATTCCCTTCAATGAAGATCCCAATCCCAATACTCACTCATCAGGACCCTCAACCCCTCTGAAAAACCAAACTTATTCCTTTTCACCTTCCAAGTCCTACAGTCGACAGTCCTCTTCTTCTGACACAGATTTGAGTTTGACACCCAAAACTG

circRNA Expression in different cancers

circRNA-miRNA-gene regulatory network

Target miRNAs

CircID	miRNA	PITA	miRanda	targetScan
chr12:22517986\|22535344	hsa-miR-572	1	1	1
chr12:22517986\|22535344	hsa-miR-637	1	1	1
chr12:22517986\|22535344	hsa-miR-3141	1	1	1
chr12:22517986\|22535344	hsa-miR-4443	1	1	1
chr12:22517986\|22535344	hsa-miR-4456	1	1	1
chr12:22517986\|22535344	hsa-miR-4710	1	1	1
chr12:22517986\|22535344	hsa-miR-4721	1	1	1
chr12:22517986\|22535344	hsa-miR-146a-3p	1	1	1
chr12:22517986\|22535344	hsa-miR-4433b-3p	1	1	1
chr12:22517986\|22535344	hsa-miR-139-5p	1	1	1
chr12:22517986\|22535344	hsa-miR-4731-5p	1	1	1
chr12:22517986\|22535344	hsa-miR-6765-5p	1	1	1
chr12:22517986\|22535344	hsa-miR-149-5p	1	1	1
chr12:22517986\|22535344	hsa-miR-6861-5p	1	1	1
chr12:22517986\|22535344	hsa-miR-6825-5p	1	1	1
chr12:22517986\|22535344	hsa-miR-1972	1	1	1
chr12:22517986\|22535344	hsa-miR-125a-3p	1	1	1
chr12:22517986\|22535344	hsa-miR-6515-5p	1	1	1
chr12:22517986\|22535344	hsa-miR-6089	1	1	1
chr12:22517986\|22535344	hsa-miR-6759-5p	1	1	1
chr12:22517986\|22535344	hsa-miR-197-5p	1	1	1
chr12:22517986\|22535344	hsa-miR-4711-5p	1	1	1
chr12:22517986\|22535344	hsa-miR-6796-5p	1	1	1
chr12:22517986\|22535344	hsa-miR-877-3p	1	1	1
chr12:22517986\|22535344	hsa-miR-6881-5p	1	1	1
chr12:22517986\|22535344	hsa-miR-2467-3p	1	1	1
chr12:22517986\|22535344	hsa-miR-5008-5p	1	1	1
chr12:22517986\|22535344	hsa-miR-3934-3p	1	1	1
chr12:22517986\|22535344	hsa-miR-548au-3p	1	1	1
chr12:22517986\|22535344	hsa-miR-3691-5p	1	1	1
chr12:22517986\|22535344	hsa-miR-144-3p	1	1	1
chr12:22517986\|22535344	hsa-miR-3667-3p	1	1	1
chr12:22517986\|22535344	hsa-miR-3616-3p	1	1	1
chr12:22517986\|22535344	hsa-miR-7112-5p	1	1	1
chr12:22517986\|22535344	hsa-miR-6743-3p	1	1	1
chr12:22517986\|22535344	hsa-miR-6887-3p	1	1	1
chr12:22517986\|22535344	hsa-miR-2276-5p	1	1	1
chr12:22517986\|22535344	hsa-miR-518c-5p	1	1	1
chr12:22517986\|22535344	hsa-miR-1178-3p	1	1	1
chr12:22517986\|22535344	hsa-miR-6734-3p	1	1	1
chr12:22517986\|22535344	hsa-miR-6731-3p	1	1	1

Target Genes

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Target miRNA Expression in different cancers

circRNA Open Reading Frame (ORF)

CircID	chr12:22517986\|22535344
ORF Type	ORF1
Protein Length	295
Nucleotide Length	885
Protein Sequence	VDDEDLQDEPLQITVLDHDTYSANDAIGKVYIDIDPLLYSEAATVISGWFPIYDTIHGIRGEINVVVKVDLFNDLNRFRQSSCGVKFFCTTSIPKCYRAVIIHGFVEELVVNEDPEYQWIDRIRTPRASNEARQRLISLMSGELQRKIGLKVLEMRGNAVVGYLQCFDLEGESGLVVRAIGTACTLDKLSSPAAFLPACNSPSKEMKESPLVHPPSHGCRSTHNSPIHTATGSRLTQNFSVSVPTLIYTGTRLLRLQSWGDAGHGQSGCRGRQAGFPSMKIPIPILTHQDPQPL*
Nucleotide Sequence	GTGGATGATGAAGACTTACAAGATGAACCTTTACAGATCACAGTTCTTGACCATGATACTTACAGTGCAAATGATGCCATTGGTAAAGTGTACATTGATATTGATCCTTTACTGTATAGTGAAGCTGCAACAGTCATCTCAGGATGGTTTCCAATTTATGACACCATACATGGTATCCGTGGGGAAATCAATGTAGTTGTCAAAGTAGACCTCTTCAATGATTTAAATCGATTTAGGCAGTCATCATGTGGAGTCAAATTCTTTTGCACAACGTCTATTCCAAAATGCTATAGAGCTGTGATAATTCATGGATTTGTAGAAGAACTTGTGGTCAATGAAGACCCAGAATATCAGTGGATTGATCGAATTCGCACACCAAGGGCATCAAATGAGGCCAGACAGAGACTCATTTCGTTAATGTCAGGTGAGCTGCAGAGGAAGATTGGCTTGAAAGTACTTGAAATGAGAGGAAATGCAGTTGTGGGGTACTTACAGTGTTTCGATCTGGAGGGCGAGTCTGGGTTAGTGGTGCGAGCCATAGGAACGGCGTGTACTCTGGATAAATTAAGTAGCCCAGCAGCATTCCTTCCTGCATGTAATTCCCCATCCAAAGAAATGAAGGAGTCTCCGCTGGTTCATCCTCCAAGCCATGGATGCCGCTCGACTCACAACAGCCCAATTCACACTGCTACTGGCTCACGACTTACTCAGAACTTCTCTGTGTCTGTTCCCACTCTCATCTATACTGGTACGAGACTGCTCAGACTCCAGAGCTGGGGAGATGCAGGCCACGGGCAGAGTGGCTGCAGAGGCAGGCAGGCAGGATTCCCTTCAATGAAGATCCCAATCCCAATACTCACTCATCAGGACCCTCAACCCCTCTGA

CircID	chr12:22517986\|22535344
ORF Type	ORF2
Protein Length	107
Nucleotide Length	321
Protein Sequence	MPLDSQQPNSHCYWLTTYSELLCVCSHSHLYWYETAQTPELGRCRPRAEWLQRQAGRIPFNEDPNPNTHSSGPSTPLKNQTYSFSPSKSYSRQSSSSDTDLSLTPKT
Nucleotide Sequence	ATGCCGCTCGACTCACAACAGCCCAATTCACACTGCTACTGGCTCACGACTTACTCAGAACTTCTCTGTGTCTGTTCCCACTCTCATCTATACTGGTACGAGACTGCTCAGACTCCAGAGCTGGGGAGATGCAGGCCACGGGCAGAGTGGCTGCAGAGGCAGGCAGGCAGGATTCCCTTCAATGAAGATCCCAATCCCAATACTCACTCATCAGGACCCTCAACCCCTCTGAAAAACCAAACTTATTCCTTTTCACCTTCCAAGTCCTACAGTCGACAGTCCTCTTCTTCTGACACAGATTTGAGTTTGACACCCAAAACT

CircID	chr12:22517986\|22535344
ORF Type	ORF3
Protein Length	69
Nucleotide Length	207
Protein Sequence	MLDMWMMKTYKMNLYRSQFLTMILTVQMMPLVKCTLILILYCIVKLQQSSQDGFQFMTPYMVSVGKSM*
Nucleotide Sequence	ATGCTAGATATGTGGATGATGAAGACTTACAAGATGAACCTTTACAGATCACAGTTCTTGACCATGATACTTACAGTGCAAATGATGCCATTGGTAAAGTGTACATTGATATTGATCCTTTACTGTATAGTGAAGCTGCAACAGTCATCTCAGGATGGTTTCCAATTTATGACACCATACATGGTATCCGTGGGGAAATCAATGTAG

CircID	chr12:22517986\|22535344
ORF Type	ORF4
Protein Length	67
Nucleotide Length	201
Protein Sequence	MGNYMQEGMLLGYLIYPEYTPFLWLAPLTQTRPPDRNTVSTPQLHFLSFQVLSSQSSSAAHLTLTK*
Nucleotide Sequence	ATGGGGAATTACATGCAGGAAGGAATGCTGCTGGGCTACTTAATTTATCCAGAGTACACGCCGTTCCTATGGCTCGCACCACTAACCCAGACTCGCCCTCCAGATCGAAACACTGTAAGTACCCCACAACTGCATTTCCTCTCATTTCAAGTACTTTCAAGCCAATCTTCCTCTGCAGCTCACCTGACATTAACGAAATGA

CircID	chr12:22517986\|22535344
ORF Type	ORF5
Protein Length	63
Nucleotide Length	189
Protein Sequence	MARTTNPDSPSRSKHCKYPTTAFPLISSTFKPIFLCSSPDINEMSLCLASFDALGVRIRSIH*
Nucleotide Sequence	ATGGCTCGCACCACTAACCCAGACTCGCCCTCCAGATCGAAACACTGTAAGTACCCCACAACTGCATTTCCTCTCATTTCAAGTACTTTCAAGCCAATCTTCCTCTGCAGCTCACCTGACATTAACGAAATGAGTCTCTGTCTGGCCTCATTTGATGCCCTTGGTGTGCGAATTCGATCAATCCACTGA

CircID	chr12:22517986\|22535344
ORF Type	ORF6
Protein Length	63
Nucleotide Length	189
Protein Sequence	MDAARLTTAQFTLLLAHDLLRTSLCLFPLSSILVRDCSDSRAGEMQATGRVAAEAGRQDSLQ*
Nucleotide Sequence	ATGGATGCCGCTCGACTCACAACAGCCCAATTCACACTGCTACTGGCTCACGACTTACTCAGAACTTCTCTGTGTCTGTTCCCACTCTCATCTATACTGGTACGAGACTGCTCAGACTCCAGAGCTGGGGAGATGCAGGCCACGGGCAGAGTGGCTGCAGAGGCAGGCAGGCAGGATTCCCTTCAATGA

CircID	chr12:22517986\|22535344
ORF Type	ORF7
Protein Length	45
Nucleotide Length	135
Protein Sequence	MRTFYFRHSSISTSQKYFLFCLPRNIESKKSCITFKKIQYMITH*
Nucleotide Sequence	ATGAGAACCTTTTATTTCAGGCATAGTAGTATTTCTACATCACAAAAATATTTTCTTTTCTGCTTACCTAGGAATATTGAGTCTAAAAAAAGTTGTATTACATTTAAGAAAATACAGTATATGATAACACATTAA

RNA Binding Protein (RBP) of circRNA

CircID	RBP	Number of Upstream Sites	Number of Downstream Sites	Number of Circ Exons Sites
chr12:22517986\|22535344	FMR1	4	0	2
chr12:22517986\|22535344	U2AF2	36	32	19
chr12:22517986\|22535344	MOV10	17	1	4
chr12:22517986\|22535344	ELAVL1	40	43	23
chr12:22517986\|22535344	ELAVL3	0	1	0
chr12:22517986\|22535344	TIAL1	4	1	0
chr12:22517986\|22535344	FUBP3	2	0	4
chr12:22517986\|22535344	FAM120A	5	0	6
chr12:22517986\|22535344	KHDRBS1	0	0	1
chr12:22517986\|22535344	CELF2	1	0	1
chr12:22517986\|22535344	PUM2	0	0	7
chr12:22517986\|22535344	PRPF8	0	0	1
chr12:22517986\|22535344	YTHDF1	1	0	0
chr12:22517986\|22535344	UPF1	6	0	0
chr12:22517986\|22535344	TAF15	0	2	0
chr12:22517986\|22535344	CAPRIN1	3	0	0
chr12:22517986\|22535344	CPSF7	9	4	3
chr12:22517986\|22535344	CPSF6	14	0	3
chr12:22517986\|22535344	NUDT21	6	1	2
chr12:22517986\|22535344	GEMIN5	0	0	1
chr12:22517986\|22535344	RBM15B	0	1	0
chr12:22517986\|22535344	CPSF1	2	0	0
chr12:22517986\|22535344	FUS	5	7	0
chr12:22517986\|22535344	DGCR8	0	1	0
chr12:22517986\|22535344	SRSF7	0	1	1
chr12:22517986\|22535344	CPSF4	1	2	0
chr12:22517986\|22535344	SRSF1	1	2	9
chr12:22517986\|22535344	NOP58	2	2	12
chr12:22517986\|22535344	CSTF2	6	6	2
chr12:22517986\|22535344	U2AF1	0	1	4
chr12:22517986\|22535344	NOP56	1	0	6
chr12:22517986\|22535344	SRSF9	0	0	3
chr12:22517986\|22535344	HNRNPU	2	0	1
chr12:22517986\|22535344	DDX54	1	0	19
chr12:22517986\|22535344	HNRNPK	0	0	3
chr12:22517986\|22535344	PCBP2	0	0	1
chr12:22517986\|22535344	HNRNPA2B1	1	0	1
chr12:22517986\|22535344	FIP1L1	5	1	5
chr12:22517986\|22535344	PTBP1	6	7	1
chr12:22517986\|22535344	HNRNPC	56	66	47
chr12:22517986\|22535344	HNRNPD	2	9	0
chr12:22517986\|22535344	TRA2A	0	0	2
chr12:22517986\|22535344	HNRNPM	2	0	0
chr12:22517986\|22535344	ZNF184	0	0	1
chr12:22517986\|22535344	HNRNPA1	14	55	4
chr12:22517986\|22535344	DDX3X	22	0	0
chr12:22517986\|22535344	ZC3H7B	13	5	2
chr12:22517986\|22535344	MSI2	0	0	2
chr12:22517986\|22535344	ACIN1	0	0	2
chr12:22517986\|22535344	TBRG4	1	0	0
chr12:22517986\|22535344	LIN28B	2	1	1
chr12:22517986\|22535344	FXR2	0	0	2
chr12:22517986\|22535344	IGF2BP1	4	1	4
chr12:22517986\|22535344	FASTKD2	0	0	1
chr12:22517986\|22535344	IGF2BP3	11	0	8
chr12:22517986\|22535344	IGF2BP2	5	1	12
chr12:22517986\|22535344	FTO	0	0	1
chr12:22517986\|22535344	TARDBP	13	3	10
chr12:22517986\|22535344	ALKBH5	1	0	0
chr12:22517986\|22535344	BUD13	0	0	1
chr12:22517986\|22535344	RBM47	4	3	5
chr12:22517986\|22535344	RTCB	2	0	0
chr12:22517986\|22535344	CSTF2T	2	3	5
chr12:22517986\|22535344	SRRM4	0	1	0
chr12:22517986\|22535344	TIA1	1	1	4
chr12:22517986\|22535344	DDX6	0	0	2
chr12:22517986\|22535344	RBM10	2	2	0
chr12:22517986\|22535344	WDR33	2	2	2
chr12:22517986\|22535344	DKC1	1	0	0
chr12:22517986\|22535344	FBL	0	0	9
chr12:22517986\|22535344	ATXN2	29	0	19
chr12:22517986\|22535344	EWSR1	1	0	0
chr12:22517986\|22535344	EIF4A3	1	1	14
chr12:22517986\|22535344	AGO2	0	0	4

CircRNA Information