CircNet

General Information

circRNA Basic Information

CircID	chr12:30674659\|30690577
Strand	-
CircType	exon
Host Gene	ENSG00000133704.9;
Algorism	find_circ;CIRI2;CIRC
Sequence	TCCTACAAGATTATCAATTTTGCCCCCAGTTTACTTCGGATTATAGTCTCTGACCATGTGGAATTCCCAGTACGACAGGCAGATTAGAATGCTAGGTTCCCCAAATCCTCACCAACTCTGTACAACTTAATGAAGTTTTGATGTAAAATGTAAACAGCATTGAAAGGCATTTTTTTCTTCATAATTTGTTTTTTCATAATTTAGATTTCAAATCCTAAATTTAAGTGGTATTTATAAATTTTCTGTTCTGTTTAATCTATTATTAAAATACAAGGATGCTCCAAGACACCTAGAAAGATAATTTATCTTTAGCATGACACTTAAAAAAGAATGTTGTGATTTTTGCTTTAAAAGAAAGCCTGTATAAAGCTGTAAAAAAAAAGTTATGCTAATGTTAAGTGGAAATACATCTGCAAAATACTTTTTCTCTTTTGCTTGTGGGCAATCTAAAGTGTTCTTGCTACCATCAAGCGTGCTCACTGATTGATCCTGTGAAATCAGGCTGGGTGTTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGTGGATCACTTGAGCCCAGGAGTTCAAGACCAGCCTGGGCAGTATGGCGAAACCCTGTCTCTACAAAAATACAAAAAAATTAACTGGCGTGGTGGTGCACGCCTGTATTCCCAACTACTTGAGAGACTGAGGTGGGAGGATCACCTAAGCCCTGGAGGTGGAGGCTGCAGTGAGCTGTGATTGTGCCCCTGGACTCCAGCCTGGGCGATAGAGTGAGACCCTGTCTCAAAAAAACCCCTAAATCCTGTGAAATCAGTCTGAACTGCTGACAGCTGCCATTTACCTGAAGAACATGGTGACACAATACTGGCCAGATCGAGAACCTCCACCAGGAGAAGCAATATTTCCATTCAACATTCACGAAAACGATCGCCAGCAAATACGTGATAACATTGTGGAAGGAATAATTCGGTCTCCAGATTTAGTGAGAGTCCAATTAACAATGTGTCTCCGTGCCATCATAAAACATGATTTTCCTGGTCACTGGCCAGGAGTGGTCGACAAGATAGACTATTACTTGCAATCACAGAGCAGTGCAAGCTGGCTTGGCAGTTTATTATGCCTGTATCAACTGGTGAAGACATATGAATATAAGAAAGCAGAAGAGAGAGAACCTCTTATAATAGCAATGCAGATATTCCTGCCTCGTATTCAGCAACAAATTGTTCAGCTCCTTCCTGATTCCTCCTATTATTCTGTATTACTGCAGAAACAAATTCTGAAAATCTTTTATGCACTTGTTCAGGTAGGTTTCTATTGCAGAAAACAAACATGGAGTCCTGTATTTCTGCCTGACACATGGAAAGTGCTCAATAAGTGTCACTTATTATTAAAAATTATTTTGTATTATCCCATATTGTTGTATATGCAGTCTGTCACTGACCGAAACATTTGTTATGTGGTGCATGACTTTATATACATTTTTTCCAGTTAGAGTGTAAGCTTCGTGAGGGCAAAGATTGTCTATCTTATTATGTCTGTAGCATGTAGCATGTTTTGTACTGAATGGATGTGGAGGCAATATCCGTCTTCTGCAACTCACAGTACAGCAGAGGTGAGCCATATATCTGTTTAGTACAAAGTGGACTGTAGTTATTATGCTACAGTGTAGAGGAAAGTAATTTAAAAAAATGTTTCATGAGTGTTTAATGAAATAAATATTTTCATCAAGGTGGTTAAAATGGAAAGTTTGACCCTCAAAGGGTATGCATTGCCTCTTCAGCTAGTGAATAACCAAACCATGACAACATGGATGGAGATCTTCCGAACTATTATCGACAGGACCGTTCCTCCTGAGACTCTGCACATTGATGAGGATGATAGACCAGAACTGGTATGGTGGAAGTGTAAGAAGTGGGCACTGCATATTGTAGCTCGGCTCTTTGAACG

circRNA Expression in different cancers

circRNA-miRNA-gene regulatory network

Target miRNAs

CircID	miRNA	PITA	miRanda	targetScan
chr12:30674659\|30690577	hsa-miR-298	1	1	1
chr12:30674659\|30690577	hsa-miR-921	1	1	1
chr12:30674659\|30690577	hsa-miR-1294	1	1	1
chr12:30674659\|30690577	hsa-miR-2278	1	1	1
chr12:30674659\|30690577	hsa-miR-3137	1	1	1
chr12:30674659\|30690577	hsa-miR-4257	1	1	1
chr12:30674659\|30690577	hsa-miR-3659	1	1	1
chr12:30674659\|30690577	hsa-miR-3908	1	1	1
chr12:30674659\|30690577	hsa-miR-4463	1	1	1
chr12:30674659\|30690577	hsa-miR-4487	1	1	1
chr12:30674659\|30690577	hsa-miR-2392	1	1	1
chr12:30674659\|30690577	hsa-miR-4522	1	1	1
chr12:30674659\|30690577	hsa-miR-4710	1	1	1
chr12:30674659\|30690577	hsa-miR-17-3p	1	1	1
chr12:30674659\|30690577	hsa-miR-4433b-3p	1	1	1
chr12:30674659\|30690577	hsa-miR-29a-5p	1	1	1
chr12:30674659\|30690577	hsa-miR-93-3p	1	1	1
chr12:30674659\|30690577	hsa-miR-22-3p	1	1	1
chr12:30674659\|30690577	hsa-miR-6840-3p	1	1	1
chr12:30674659\|30690577	hsa-miR-4433a-3p	1	1	1
chr12:30674659\|30690577	hsa-miR-6894-5p	1	1	1
chr12:30674659\|30690577	hsa-miR-6799-5p	1	1	1
chr12:30674659\|30690577	hsa-miR-8071	1	1	1
chr12:30674659\|30690577	hsa-miR-6833-5p	1	1	1
chr12:30674659\|30690577	hsa-miR-4786-5p	1	1	1
chr12:30674659\|30690577	hsa-miR-6880-5p	1	1	1
chr12:30674659\|30690577	hsa-miR-7847-3p	1	1	1
chr12:30674659\|30690577	hsa-miR-6762-3p	1	1	1
chr12:30674659\|30690577	hsa-miR-6772-5p	1	1	1
chr12:30674659\|30690577	hsa-miR-6868-3p	1	1	1
chr12:30674659\|30690577	hsa-miR-3190-3p	1	1	1
chr12:30674659\|30690577	hsa-miR-2467-5p	1	1	1
chr12:30674659\|30690577	hsa-miR-2277-3p	1	1	1
chr12:30674659\|30690577	hsa-miR-3691-5p	1	1	1
chr12:30674659\|30690577	hsa-miR-4764-5p	1	1	1
chr12:30674659\|30690577	hsa-miR-146b-3p	1	1	1
chr12:30674659\|30690577	hsa-miR-574-5p	1	1	1
chr12:30674659\|30690577	hsa-miR-7152-3p	1	1	1
chr12:30674659\|30690577	hsa-miR-20b-3p	1	1	1

Target Genes

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Target miRNA Expression in different cancers

circRNA Open Reading Frame (ORF)

CircID	chr12:30674659\|30690577
ORF Type	ORF1
Protein Length	214
Nucleotide Length	642
Protein Sequence	MVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRAIIKHDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLPRIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQVGFYCRKQTWSPVFLPDTWKVLNKCHLLLKIILYYPILLYMQSVTDRNICYVVHDFIYIFSS*
Nucleotide Sequence	ATGGTGACACAATACTGGCCAGATCGAGAACCTCCACCAGGAGAAGCAATATTTCCATTCAACATTCACGAAAACGATCGCCAGCAAATACGTGATAACATTGTGGAAGGAATAATTCGGTCTCCAGATTTAGTGAGAGTCCAATTAACAATGTGTCTCCGTGCCATCATAAAACATGATTTTCCTGGTCACTGGCCAGGAGTGGTCGACAAGATAGACTATTACTTGCAATCACAGAGCAGTGCAAGCTGGCTTGGCAGTTTATTATGCCTGTATCAACTGGTGAAGACATATGAATATAAGAAAGCAGAAGAGAGAGAACCTCTTATAATAGCAATGCAGATATTCCTGCCTCGTATTCAGCAACAAATTGTTCAGCTCCTTCCTGATTCCTCCTATTATTCTGTATTACTGCAGAAACAAATTCTGAAAATCTTTTATGCACTTGTTCAGGTAGGTTTCTATTGCAGAAAACAAACATGGAGTCCTGTATTTCTGCCTGACACATGGAAAGTGCTCAATAAGTGTCACTTATTATTAAAAATTATTTTGTATTATCCCATATTGTTGTATATGCAGTCTGTCACTGACCGAAACATTTGTTATGTGGTGCATGACTTTATATACATTTTTTCCAGTTAG

CircID	chr12:30674659\|30690577
ORF Type	ORF2
Protein Length	78
Nucleotide Length	234
Protein Sequence	MAHLCCTVSCRRRILPPHPFSTKHATCYRHNKIDNLCPHEAYTLTGKNVYKVMHHITNVSVSDRLHIQQYGIIQNNF*
Nucleotide Sequence	ATGGCTCACCTCTGCTGTACTGTGAGTTGCAGAAGACGGATATTGCCTCCACATCCATTCAGTACAAAACATGCTACATGCTACAGACATAATAAGATAGACAATCTTTGCCCTCACGAAGCTTACACTCTAACTGGAAAAAATGTATATAAAGTCATGCACCACATAACAAATGTTTCGGTCAGTGACAGACTGCATATACAACAATATGGGATAATACAAAATAATTTTTAA

CircID	chr12:30674659\|30690577
ORF Type	ORF3
Protein Length	70
Nucleotide Length	210
Protein Sequence	MEILLLLVEVLDLASIVSPCSSGKWQLSAVQTDFTGFRGFFETGSHSIAQAGVQGHNHSSLQPPPPGLR*
Nucleotide Sequence	ATGGAAATATTGCTTCTCCTGGTGGAGGTTCTCGATCTGGCCAGTATTGTGTCACCATGTTCTTCAGGTAAATGGCAGCTGTCAGCAGTTCAGACTGATTTCACAGGATTTAGGGGTTTTTTTGAGACAGGGTCTCACTCTATCGCCCAGGCTGGAGTCCAGGGGCACAATCACAGCTCACTGCAGCCTCCACCTCCAGGGCTTAGGTGA

CircID	chr12:30674659\|30690577
ORF Type	ORF4
Protein Length	69
Nucleotide Length	207
Protein Sequence	MESLTLKGYALPLQLVNNQTMTTWMEIFRTIIDRTVPPETLHIDEDDRPELVWWKCKKWALHIVARLFE
Nucleotide Sequence	ATGGAAAGTTTGACCCTCAAAGGGTATGCATTGCCTCTTCAGCTAGTGAATAACCAAACCATGACAACATGGATGGAGATCTTCCGAACTATTATCGACAGGACCGTTCCTCCTGAGACTCTGCACATTGATGAGGATGATAGACCAGAACTGGTATGGTGGAAGTGTAAGAAGTGGGCACTGCATATTGTAGCTCGGCTCTTTGAA

CircID	chr12:30674659\|30690577
ORF Type	ORF5
Protein Length	61
Nucleotide Length	183
Protein Sequence	MCQAEIQDSMFVFCNRNLPEQVHKRFSEFVSAVIQNNRRNQEGAEQFVAEYEAGISALLL*
Nucleotide Sequence	ATGTGTCAGGCAGAAATACAGGACTCCATGTTTGTTTTCTGCAATAGAAACCTACCTGAACAAGTGCATAAAAGATTTTCAGAATTTGTTTCTGCAGTAATACAGAATAATAGGAGGAATCAGGAAGGAGCTGAACAATTTGTTGCTGAATACGAGGCAGGAATATCTGCATTGCTATTATAA

CircID	chr12:30674659\|30690577
ORF Type	ORF6
Protein Length	100
Nucleotide Length	300
Protein Sequence	LLAIVFVNVEWKYCFSWWRFSIWPVLCHHVLQVNGSCQQFRLISQDLGVFLRQGLTLSPRLESRGTITAHCSLHLQGLGDPPTSVSQVVGNTGVHHHAS*
Nucleotide Sequence	TTGCTGGCGATCGTTTTCGTGAATGTTGAATGGAAATATTGCTTCTCCTGGTGGAGGTTCTCGATCTGGCCAGTATTGTGTCACCATGTTCTTCAGGTAAATGGCAGCTGTCAGCAGTTCAGACTGATTTCACAGGATTTAGGGGTTTTTTTGAGACAGGGTCTCACTCTATCGCCCAGGCTGGAGTCCAGGGGCACAATCACAGCTCACTGCAGCCTCCACCTCCAGGGCTTAGGTGATCCTCCCACCTCAGTCTCTCAAGTAGTTGGGAATACAGGCGTGCACCACCACGCCAGTTAA

CircID	chr12:30674659\|30690577
ORF Type	ORF7
Protein Length	48
Nucleotide Length	144
Protein Sequence	MQCPLLTLPPYQFWSIILINVQSLRRNGPVDNSSEDLHPCCHGLVIH*
Nucleotide Sequence	ATGCAGTGCCCACTTCTTACACTTCCACCATACCAGTTCTGGTCTATCATCCTCATCAATGTGCAGAGTCTCAGGAGGAACGGTCCTGTCGATAATAGTTCGGAAGATCTCCATCCATGTTGTCATGGTTTGGTTATTCACTAG

CircID	chr12:30674659\|30690577
ORF Type	ORF8
Protein Length	42
Nucleotide Length	126
Protein Sequence	MSSPVDTGIINCQASLHCSVIASNSLSCRPLLASDQENHVL*
Nucleotide Sequence	ATGTCTTCACCAGTTGATACAGGCATAATAAACTGCCAAGCCAGCTTGCACTGCTCTGTGATTGCAAGTAATAGTCTATCTTGTCGACCACTCCTGGCCAGTGACCAGGAAAATCATGTTTTATGA

CircID	chr12:30674659\|30690577
ORF Type	ORF9
Protein Length	40
Nucleotide Length	120
Protein Sequence	MPVIPALWEAEVGGSLEPRSSRPAWAVWRNPVSTKIQKN*
Nucleotide Sequence	ATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGTGGATCACTTGAGCCCAGGAGTTCAAGACCAGCCTGGGCAGTATGGCGAAACCCTGTCTCTACAAAAATACAAAAAAATTAA

CircID	chr12:30674659\|30690577
ORF Type	ORF10
Protein Length	38
Nucleotide Length	114
Protein Sequence	MKKQIMKKKMPFNAVYILHQNFIKLYRVGEDLGNLAF*
Nucleotide Sequence	ATGAAAAAACAAATTATGAAGAAAAAAATGCCTTTCAATGCTGTTTACATTTTACATCAAAACTTCATTAAGTTGTACAGAGTTGGTGAGGATTTGGGGAACCTAGCATTCTAA

CircID	chr12:30674659\|30690577
ORF Type	ORF11
Protein Length	35
Nucleotide Length	105
Protein Sequence	MMARRHIVNWTLTKSGDRIIPSTMLSRICWRSFS*
Nucleotide Sequence	ATGATGGCACGGAGACACATTGTTAATTGGACTCTCACTAAATCTGGAGACCGAATTATTCCTTCCACAATGTTATCACGTATTTGCTGGCGATCGTTTTCGTGA

CircID	chr12:30674659\|30690577
ORF Type	ORF12
Protein Length	34
Nucleotide Length	102
Protein Sequence	MSVACSMFCTEWMWRQYPSSATHSTAEVSHISV*
Nucleotide Sequence	ATGTCTGTAGCATGTAGCATGTTTTGTACTGAATGGATGTGGAGGCAATATCCGTCTTCTGCAACTCACAGTACAGCAGAGGTGAGCCATATATCTGTTTAG

CircID	chr12:30674659\|30690577
ORF Type	ORF13
Protein Length	34
Nucleotide Length	102
Protein Sequence	MLMLSGNTSAKYFFSFACGQSKVFLLPSSVLTD*
Nucleotide Sequence	ATGCTAATGTTAAGTGGAAATACATCTGCAAAATACTTTTTCTCTTTTGCTTGTGGGCAATCTAAAGTGTTCTTGCTACCATCAAGCGTGCTCACTGATTGA

CircID	chr12:30674659\|30690577
ORF Type	ORF14
Protein Length	83
Nucleotide Length	249
Protein Sequence	VSTLDGSKNTLDCPQAKEKKYFADVFPLNISITFFLQLYTGFLLKQKSQHSFLSVMLKINYLSRCLGASLYFNNRLNRTENL*
Nucleotide Sequence	GTGAGCACGCTTGATGGTAGCAAGAACACTTTAGATTGCCCACAAGCAAAAGAGAAAAAGTATTTTGCAGATGTATTTCCACTTAACATTAGCATAACTTTTTTTTTACAGCTTTATACAGGCTTTCTTTTAAAGCAAAAATCACAACATTCTTTTTTAAGTGTCATGCTAAAGATAAATTATCTTTCTAGGTGTCTTGGAGCATCCTTGTATTTTAATAATAGATTAAACAGAACAGAAAATTTATAA

CircID	chr12:30674659\|30690577
ORF Type	ORF15
Protein Length	30
Nucleotide Length	90
Protein Sequence	MCRVSGGTVLSIIVRKISIHVVMVWLFTS*
Nucleotide Sequence	ATGTGCAGAGTCTCAGGAGGAACGGTCCTGTCGATAATAGTTCGGAAGATCTCCATCCATGTTGTCATGGTTTGGTTATTCACTAGCTGA

CircID	chr12:30674659\|30690577
ORF Type	ORF16
Protein Length	60
Nucleotide Length	180
Protein Sequence	VDHLSPGVQDQPGQYGETLSLQKYKKINWRGGARLYSQLLERLRWEDHLSPGGGGCSEL*
Nucleotide Sequence	GTGGATCACTTGAGCCCAGGAGTTCAAGACCAGCCTGGGCAGTATGGCGAAACCCTGTCTCTACAAAAATACAAAAAAATTAACTGGCGTGGTGGTGCACGCCTGTATTCCCAACTACTTGAGAGACTGAGGTGGGAGGATCACCTAAGCCCTGGAGGTGGAGGCTGCAGTGAGCTGTGA

RNA Binding Protein (RBP) of circRNA

CircID	RBP	Number of Upstream Sites	Number of Downstream Sites	Number of Circ Exons Sites
chr12:30674659\|30690577	FMR1	0	4	5
chr12:30674659\|30690577	U2AF2	9	3	23
chr12:30674659\|30690577	ELAVL1	6	2	7
chr12:30674659\|30690577	KHDRBS1	1	0	0
chr12:30674659\|30690577	CELF2	0	0	1
chr12:30674659\|30690577	PRPF8	0	2	1
chr12:30674659\|30690577	UPF1	0	1	0
chr12:30674659\|30690577	DDX54	0	0	21
chr12:30674659\|30690577	TNRC6A	0	1	1
chr12:30674659\|30690577	CPSF7	0	0	2
chr12:30674659\|30690577	CPSF6	0	0	1
chr12:30674659\|30690577	TROVE2	0	2	0
chr12:30674659\|30690577	FUS	1	0	0
chr12:30674659\|30690577	DGCR8	0	1	0
chr12:30674659\|30690577	QKI	0	0	2
chr12:30674659\|30690577	DDX59	0	0	3
chr12:30674659\|30690577	SRSF1	0	0	4
chr12:30674659\|30690577	NOP58	0	2	4
chr12:30674659\|30690577	TARBP2	0	0	19
chr12:30674659\|30690577	NONO	0	0	1
chr12:30674659\|30690577	ADAR	0	0	2
chr12:30674659\|30690577	NOP56	0	2	1
chr12:30674659\|30690577	SRSF9	0	0	1
chr12:30674659\|30690577	HNRNPU	1	0	0
chr12:30674659\|30690577	ZNF622	0	0	1
chr12:30674659\|30690577	EFTUD2	0	0	2
chr12:30674659\|30690577	HNRNPK	0	0	3
chr12:30674659\|30690577	RBM15	0	0	1
chr12:30674659\|30690577	SF3A3	1	0	1
chr12:30674659\|30690577	PTBP1	1	1	6
chr12:30674659\|30690577	HNRNPC	1	0	4
chr12:30674659\|30690577	TRA2A	0	0	2
chr12:30674659\|30690577	DHX9	0	0	5
chr12:30674659\|30690577	HNRNPA1	1	0	4
chr12:30674659\|30690577	DDX3X	1	0	1
chr12:30674659\|30690577	YTHDC1	1	0	0
chr12:30674659\|30690577	SMNDC1	0	0	2
chr12:30674659\|30690577	MSI2	0	2	2
chr12:30674659\|30690577	ACIN1	0	0	1
chr12:30674659\|30690577	LIN28B	0	0	1
chr12:30674659\|30690577	RANGAP1	1	0	1
chr12:30674659\|30690577	FXR1	0	0	5
chr12:30674659\|30690577	FXR2	0	2	3
chr12:30674659\|30690577	IGF2BP1	0	0	4
chr12:30674659\|30690577	BUD13	0	2	4
chr12:30674659\|30690577	IGF2BP3	0	0	4
chr12:30674659\|30690577	IGF2BP2	1	2	19
chr12:30674659\|30690577	TARDBP	0	1	8
chr12:30674659\|30690577	STAU1	1	0	0
chr12:30674659\|30690577	GTF2F1	0	0	1
chr12:30674659\|30690577	KHSRP	0	0	5
chr12:30674659\|30690577	RBM47	0	0	3
chr12:30674659\|30690577	DDX24	0	0	1
chr12:30674659\|30690577	CSTF2T	0	0	6
chr12:30674659\|30690577	SRRM4	1	0	0
chr12:30674659\|30690577	RBFOX2	0	1	2
chr12:30674659\|30690577	U2AF1	0	0	1
chr12:30674659\|30690577	RBM22	0	1	0
chr12:30674659\|30690577	DKC1	1	0	0
chr12:30674659\|30690577	AGO2	0	2	7
chr12:30674659\|30690577	EWSR1	1	0	0
chr12:30674659\|30690577	EIF4A3	1	5	14
chr12:30674659\|30690577	FBL	1	1	2

CircRNA Information