CircNet

General Information

circRNA Basic Information

CircID	chr13:41358304\|41367652
Strand	+
CircType	exon
Host Gene	ENSG00000172766.18;
Algorism	CIRI2;DCC;
Sequence	AGAATGGGGAGAAGGAACCCCCGACAACACTACTCTGGGTTCAGTATTTCCTGGCACAGCACTTTGATAAACTTGGACAGTATTCTTTGGCTTTGGATTATATTAATGCTGCAATTGCTAGTACTCCAACTCTAATAGAATTATTCTATATGAAAGCAAAAATTTACAAGGTAAAATCTGAATCCTGTTTTTTGAGTAGTTGAAGAATTCAGCTACTTTAAGAATCCTTGGAGTTTTTTCTTTGTGGAAACAAGTTCTAGGGCACCCTGATAATCTTTTTCTAATAATCCTGTGTAGTTTCATGTTATATTAATTGTATAATCAATGTGTAATTAGATGTGTAATCATTTGAGCTCTTAGTAAATGTGAACTGTAATTTTGATTTCTAAATAAATTTGACAGAAATGGTGACAGACATATAGGTAATCTCAAAGAAGCTGCAAAGTGGATGGATGAAGCACAGTCTTTGGACACAGCTGATAGATTCATCAATTCCAAATGTGCAAAATACATGCTTCGAGCAAATATGATAAAAGAAGCAGAGGAAATGTGCTCCAAGTTCACAAGGGAAGGAACATCTGCCATGGAAAATCTAAATGAAATGCAGTGTATGTGGTTTCAGACAGAATGCATTTCAGCTTATCAGCGTCTGGGGAGATACGGGGATGCCTTGAAAAAATGTCATGAAGTAGAAAGGGTAAGTTGTTAGAATTTCGACTTCAGTTTTCACTGTAAGGTGATAAAAAGCAGGTAGATTTCTACACAGGATCATCTGCCTCTTCTAACTTCTCTGGGAGCTTCATTGTGAAAAAAATTCTTGATCTTTAACCTTTACATTCAGAAGTTGTAAACAATGGATTGCTTTACTGATCCTCAAGTGATTATGCTTTTGACATGTCTATATATTTTTGTCTGAAGGAAAAAGATTGTTAGTAAACAATTATTGCTATTAACATAAATTCAAAATTTATGTTCCCTAATTAGGCCATTATTTTGATATTCATCACCACCCTAAGAGGACACACAGCTGATGGCAACCTCTTTCCCCTTTAAAACATCAGGATCTGGTCCGCAGTCAGCCTCTCTCCAGTTTGTCTTCCCAGGATATTTGCTCTCACATTCAGTATTCTGTATAACAATCTATGGCCAGTTTGCAGGCTTATTTTATTGCTTGCTTTTAGGATTATTTGTGTGATGTGCCTTAGTGAGGGGACTTTTCTTTTCCTTTGTGTGAATTTTTGTTTTCCTGTTCTTTGTCATCTCTGAAGCACTCTCCTTCCACATGGACCACAGGAGGAAAAGAGCCGCAAATGCACCCCTGAGGCAGTCCTCAGCAGCCCTCAGTTGTGGGGGCAATCGGCACCACTGTTCCCATCCTGACGCAGTATAGAACCACAGGCATCGTAGTCAGCATTTTTTTGAGATAACTGATGACCAATTCGACTTCCATACATACTGCATGAGAAAGATGACCCTTCGTGCCTATGTTGACCTTTTGAGATTAGAAGATATACTCAGAAGACATGCCTTTTATTTCAAGGCTGCTAGATCAGCGATTGAAATATACTTGAAATTGTATGATAATCCCTTAACCAATGAAAGCAAACAACAAGAAATAAACTCAG

circRNA Expression in different cancers

circRNA-miRNA-gene regulatory network

Target miRNAs

CircID	miRNA	miRanda	targetScan
chr13:41358304\|41367652	hsa-miR-127-5p	1	1
chr13:41358304\|41367652	hsa-miR-103a-2-5p	1	1
chr13:41358304\|41367652	hsa-miR-216a-5p	1	1
chr13:41358304\|41367652	hsa-miR-218-5p	1	1
chr13:41358304\|41367652	hsa-miR-101-5p	1	1

Target Genes

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Target miRNA Expression in different cancers

circRNA Open Reading Frame (ORF)

CircID	chr13:41358304\|41367652
ORF Type	ORF1
Protein Length	88
Nucleotide Length	264
Protein Sequence	MADVPSLVNLEHISSASFIIFARSMYFAHLELMNLSAVSKDCASSIHFAASLRLPICLSPFLSNLFRNQNYSSHLLRAQMITHLITH*
Nucleotide Sequence	ATGGCAGATGTTCCTTCCCTTGTGAACTTGGAGCACATTTCCTCTGCTTCTTTTATCATATTTGCTCGAAGCATGTATTTTGCACATTTGGAATTGATGAATCTATCAGCTGTGTCCAAAGACTGTGCTTCATCCATCCACTTTGCAGCTTCTTTGAGATTACCTATATGTCTGTCACCATTTCTGTCAAATTTATTTAGAAATCAAAATTACAGTTCACATTTACTAAGAGCTCAAATGATTACACATCTAATTACACATTGA

CircID	chr13:41358304\|41367652
ORF Type	ORF2
Protein Length	87
Nucleotide Length	261
Protein Sequence	MDEAQSLDTADRFINSKCAKYMLRANMIKEAEEMCSKFTREGTSAMENLNEMQCMWFQTECISAYQRLGRYGDALKKCHEVERVSC*
Nucleotide Sequence	ATGGATGAAGCACAGTCTTTGGACACAGCTGATAGATTCATCAATTCCAAATGTGCAAAATACATGCTTCGAGCAAATATGATAAAAGAAGCAGAGGAAATGTGCTCCAAGTTCACAAGGGAAGGAACATCTGCCATGGAAAATCTAAATGAAATGCAGTGTATGTGGTTTCAGACAGAATGCATTTCAGCTTATCAGCGTCTGGGGAGATACGGGGATGCCTTGAAAAAATGTCATGAAGTAGAAAGGGTAAGTTGTTAG

CircID	chr13:41358304\|41367652
ORF Type	ORF3
Protein Length	62
Nucleotide Length	186
Protein Sequence	MKLHRIIRKRLSGCPRTCFHKEKTPRILKVAEFFNYSKNRIQILPCKFLLSYRIILLELEY*
Nucleotide Sequence	ATGAAACTACACAGGATTATTAGAAAAAGATTATCAGGGTGCCCTAGAACTTGTTTCCACAAAGAAAAAACTCCAAGGATTCTTAAAGTAGCTGAATTCTTCAACTACTCAAAAAACAGGATTCAGATTTTACCTTGTAAATTTTTGCTTTCATATAGAATAATTCTATTAGAGTTGGAGTACTAG

CircID	chr13:41358304\|41367652
ORF Type	ORF4
Protein Length	55
Nucleotide Length	165
Protein Sequence	MRKMTLRAYVDLLRLEDILRRHAFYFKAARSAIEIYLKLYDNPLTNESKQQEINS
Nucleotide Sequence	ATGAGAAAGATGACCCTTCGTGCCTATGTTGACCTTTTGAGATTAGAAGATATACTCAGAAGACATGCCTTTTATTTCAAGGCTGCTAGATCAGCGATTGAAATATACTTGAAATTGTATGATAATCCCTTAACCAATGAAAGCAAACAACAAGAAATAAACTCA

CircID	chr13:41358304\|41367652
ORF Type	ORF5
Protein Length	55
Nucleotide Length	165
Protein Sequence	MATSFPFKTSGSGPQSASLQFVFPGYLLSHSVFCITIYGQFAGLFYCLLLGLFV*
Nucleotide Sequence	ATGGCAACCTCTTTCCCCTTTAAAACATCAGGATCTGGTCCGCAGTCAGCCTCTCTCCAGTTTGTCTTCCCAGGATATTTGCTCTCACATTCAGTATTCTGTATAACAATCTATGGCCAGTTTGCAGGCTTATTTTATTGCTTGCTTTTAGGATTATTTGTGTGA

CircID	chr13:41358304\|41367652
ORF Type	ORF6
Protein Length	46
Nucleotide Length	138
Protein Sequence	MILCRNLPAFYHLTVKTEVEILTTYPFYFMTFFQGIPVSPQTLIS*
Nucleotide Sequence	ATGATCCTGTGTAGAAATCTACCTGCTTTTTATCACCTTACAGTGAAAACTGAAGTCGAAATTCTAACAACTTACCCTTTCTACTTCATGACATTTTTTCAAGGCATCCCCGTATCTCCCCAGACGCTGATAAGCTGA

CircID	chr13:41358304\|41367652
ORF Type	ORF7
Protein Length	44
Nucleotide Length	132
Protein Sequence	MGRRNPRQHYSGFSISWHSTLINLDSILWLWIILMLQLLVLQL*
Nucleotide Sequence	ATGGGGAGAAGGAACCCCCGACAACACTACTCTGGGTTCAGTATTTCCTGGCACAGCACTTTGATAAACTTGGACAGTATTCTTTGGCTTTGGATTATATTAATGCTGCAATTGCTAGTACTCCAACTCTAA

CircID	chr13:41358304\|41367652
ORF Type	ORF8
Protein Length	40
Nucleotide Length	120
Protein Sequence	MWKESASEMTKNRKTKIHTKEKKSPLTKAHHTNNPKSKQ*
Nucleotide Sequence	ATGTGGAAGGAGAGTGCTTCAGAGATGACAAAGAACAGGAAAACAAAAATTCACACAAAGGAAAAGAAAAGTCCCCTCACTAAGGCACATCACACAAATAATCCTAAAAGCAAGCAATAA

CircID	chr13:41358304\|41367652
ORF Type	ORF9
Protein Length	40
Nucleotide Length	120
Protein Sequence	MEVELVISYLKKMLTTMPVVLYCVRMGTVVPIAPTTEGC*
Nucleotide Sequence	ATGGAAGTCGAATTGGTCATCAGTTATCTCAAAAAAATGCTGACTACGATGCCTGTGGTTCTATACTGCGTCAGGATGGGAACAGTGGTGCCGATTGCCCCCACAACTGAGGGCTGCTGA

CircID	chr13:41358304\|41367652
ORF Type	ORF10
Protein Length	38
Nucleotide Length	114
Protein Sequence	MYGSRIGHQLSQKNADYDACGSILRQDGNSGADCPHN*
Nucleotide Sequence	ATGTATGGAAGTCGAATTGGTCATCAGTTATCTCAAAAAAATGCTGACTACGATGCCTGTGGTTCTATACTGCGTCAGGATGGGAACAGTGGTGCCGATTGCCCCCACAACTGA

CircID	chr13:41358304\|41367652
ORF Type	ORF11
Protein Length	36
Nucleotide Length	108
Protein Sequence	MDHRRKRAANAPLRQSSAALSCGGNRHHCSHPDAV*
Nucleotide Sequence	ATGGACCACAGGAGGAAAAGAGCCGCAAATGCACCCCTGAGGCAGTCCTCAGCAGCCCTCAGTTGTGGGGGCAATCGGCACCACTGTTCCCATCCTGACGCAGTATAG

CircID	chr13:41358304\|41367652
ORF Type	ORF12
Protein Length	34
Nucleotide Length	102
Protein Sequence	MCKIHASSKYDKRSRGNVLQVHKGRNICHGKSK*
Nucleotide Sequence	ATGTGCAAAATACATGCTTCGAGCAAATATGATAAAAGAAGCAGAGGAAATGTGCTCCAAGTTCACAAGGGAAGGAACATCTGCCATGGAAAATCTAAATGA

CircID	chr13:41358304\|41367652
ORF Type	ORF13
Protein Length	69
Nucleotide Length	207
Protein Sequence	IFHGRCSFPCELGAHFLCFFYHICSKHVFCTFGIDESISCVQRLCFIHPLCSFFEITYMSVTISVKFI*
Nucleotide Sequence	ATTTTCCATGGCAGATGTTCCTTCCCTTGTGAACTTGGAGCACATTTCCTCTGCTTCTTTTATCATATTTGCTCGAAGCATGTATTTTGCACATTTGGAATTGATGAATCTATCAGCTGTGTCCAAAGACTGTGCTTCATCCATCCACTTTGCAGCTTCTTTGAGATTACCTATATGTCTGTCACCATTTCTGTCAAATTTATTTAG

RNA Binding Protein (RBP) of circRNA

CircID	RBP	Number of Upstream Sites	Number of Downstream Sites	Number of Circ Exons Sites
chr13:41358304\|41367652	KHSRP	1	0	1
chr13:41358304\|41367652	ELAVL1	8	5	3
chr13:41358304\|41367652	SF3B4	1	0	1
chr13:41358304\|41367652	CELF2	2	0	1
chr13:41358304\|41367652	CNBP	0	0	1
chr13:41358304\|41367652	UPF1	1	0	0
chr13:41358304\|41367652	TAF15	1	0	0
chr13:41358304\|41367652	CAPRIN1	1	1	0
chr13:41358304\|41367652	CPSF7	0	0	1
chr13:41358304\|41367652	CPSF6	0	1	0
chr13:41358304\|41367652	FUS	1	0	0
chr13:41358304\|41367652	DGCR8	0	0	1
chr13:41358304\|41367652	SRSF1	1	0	12
chr13:41358304\|41367652	NOP58	2	1	10
chr13:41358304\|41367652	U2AF1	4	0	5
chr13:41358304\|41367652	U2AF2	11	4	24
chr13:41358304\|41367652	NOP56	1	0	4
chr13:41358304\|41367652	DDX54	0	0	16
chr13:41358304\|41367652	LSM11	1	0	0
chr13:41358304\|41367652	HNRNPM	0	1	0
chr13:41358304\|41367652	SF3A3	0	0	1
chr13:41358304\|41367652	FIP1L1	1	0	1
chr13:41358304\|41367652	PTBP1	5	11	0
chr13:41358304\|41367652	HNRNPC	5	3	0
chr13:41358304\|41367652	SUGP2	0	3	0
chr13:41358304\|41367652	TRA2A	1	0	3
chr13:41358304\|41367652	HNRNPA1	2	3	0
chr13:41358304\|41367652	ZC3H7B	0	0	1
chr13:41358304\|41367652	SMNDC1	0	0	2
chr13:41358304\|41367652	ACIN1	0	0	1
chr13:41358304\|41367652	LIN28B	0	2	3
chr13:41358304\|41367652	IGF2BP1	0	0	1
chr13:41358304\|41367652	IGF2BP3	0	0	1
chr13:41358304\|41367652	IGF2BP2	0	0	8
chr13:41358304\|41367652	NPM1	0	0	1
chr13:41358304\|41367652	FTO	0	0	1
chr13:41358304\|41367652	TARDBP	0	4	1
chr13:41358304\|41367652	BUD13	1	0	1
chr13:41358304\|41367652	RBFOX2	1	0	0
chr13:41358304\|41367652	PRPF8	0	0	1
chr13:41358304\|41367652	RBM47	0	0	2
chr13:41358304\|41367652	CSTF2T	3	0	3
chr13:41358304\|41367652	RBM22	0	0	1
chr13:41358304\|41367652	WDR33	1	0	0
chr13:41358304\|41367652	DKC1	0	1	1
chr13:41358304\|41367652	AGO2	0	0	4
chr13:41358304\|41367652	ATXN2	0	3	0
chr13:41358304\|41367652	EIF4A3	0	0	11
chr13:41358304\|41367652	FBL	0	2	5

CircRNA Information