CircNet

General Information

circRNA Basic Information

CircID	chr17:4085670\|4109863
Strand	-
CircType	exon
Host Gene	ENSG00000074755.14;
Algorism	find_circ;CIRI2;DCC;
Sequence	ATGTCCAGATTAACATAAAGCGTTGTCTTAGCGATGGCTGCGACACTAGAATTCATGGTCTCAGGGCTGTTGGCTTTCAGAGAGTTAAGAAGTCTGGGGTCTCAGTCTCAGATGCTTCTGCAATATGGTATTGGTCTCTGCTGACATCTCTGGTGACGGCTTCTATGGAGACAAATCCCGCCTTTGTCCAGACAGTGCTGCACAATACTCAGAAGGCGCTGCGGCACATGCCTCCACTCTCTCTCTCACCAGGATCTACAGATTTCTCAACTTTCCTCTCCCCTAATGTGCTGGAAGAAGTGGACAGTTTCCTCATAAGGATAACTAGCTGCTGTTCTACCCCAGAGGTAGAACTGACTCTTCTGGCTTTTGCTCTCGCAAGAGGAAGTGTTGCCAAAGTCATGAGCTCTCTATGCACCATCACTGACCATCTGGACACGCAGTATGATGCCTCATCCCTCATCTTGTCCATGGCGTCAGTCAGACAGAACCTGCTCCTCAAATATGGTAAACCTCTCCAGTTGACTCTTCAGGCATGTGATGTCAAAGGAAAAGAAGATAAGTCTGGACCCGAAAACCTCCTTGTTGAACCGTGGACAAGGGATGGTTTTCTTACGGAAACTGGAAAAACCAGAGCCAGCACTATTTTTTCTACCGGAACTGAATCTGCCTTCCAAGTTACACAGATAAGAATTATGGTTCGACGTGGTGGCATTGGTGCCCAGTGTGGGTTGGTGTTTGCCTATAACTCATCTTCAGATAAATTTTGTGCGGAAGAACACTTCAAAAGGTTTGAAAAATATGACAAATGGAAGCTTCAGGAGCTCAGGCAATTTGTAAAAAGCAGGATTGGTTGCTCATCTGATGACCTTGGAGAGGATGATCCTATTGGCTGGTTTGAACTGGAAGAAGAATGGGATGAAGCAGATGTGAAGCTGCAACAGTGCAGAGTTGCCAAATATTTGATGGTGAAGTTCCTCTGCACCCGTCAGGAGTCAGCAGAGCGCTTGGGAGTGCAAGGCTTGACCATCAGTGGGTACCTCCGGCCTGCAAGAGCAGAAGCAGAACAGAGCGTCACCTGTGCACACTGCAGAAAGGACACAGAGGAGAGTGTCTGTGGGGCCACGTTGCTCCTCAGGACCCTTCAGTTTATCCAGCAGCTCGCCCATGACCTGGTGCAGCAGAAGGAAAGTGGCTTAAAATATAAATCTTTTCTGGACTTCGCGGGTCTTGATTTGCAGATCTTCTGGAATTTTTACAGTAAATTAAAGCAAAACCCGAGGGAAGAATGCGTCTCTGCCCAAACCCTGCTTCTGCAGCTACTCCAGAGCTGCTTCTCTGTGCTGCAGGGAGATGTACTGGCTGCTTCTGAGGAGGAAAAGGCTCCAATCCAAAGCCCTAAAGGAGTAGAGGCTGCCAAGGAGCTGTACACACACTTGTGTGATGTGGTGGACAAGGTGGATGGAGACTCTGTGCCCATGGAGATACTAAAACAAGAAGTCAGGAATACCCTTCTCAATGGGGCTGCCATCTTCTTTCCTAATCGACAGACCCGACGGAACCATCTCTTCACCATGATG

circRNA Expression in different cancers

circRNA-miRNA-gene regulatory network

Target miRNAs

CircID	miRNA	PITA	miRanda	targetScan
chr17:4085670\|4109863	hsa-miR-637	1	1	1
chr17:4085670\|4109863	hsa-miR-892b	1	1	1
chr17:4085670\|4109863	hsa-miR-147b-5p	1	1	1
chr17:4085670\|4109863	hsa-miR-147b-3p	1	1	1
chr17:4085670\|4109863	hsa-miR-3138	1	1	1
chr17:4085670\|4109863	hsa-miR-3154	1	1	1
chr17:4085670\|4109863	hsa-miR-4268	1	1	1
chr17:4085670\|4109863	hsa-miR-3621	1	1	1
chr17:4085670\|4109863	hsa-miR-4428	1	1	1
chr17:4085670\|4109863	hsa-miR-4462	1	1	1
chr17:4085670\|4109863	hsa-miR-4487	1	1	1
chr17:4085670\|4109863	hsa-miR-4642	1	1	1
chr17:4085670\|4109863	hsa-miR-4656	1	1	1
chr17:4085670\|4109863	hsa-miR-4686	1	1	1
chr17:4085670\|4109863	hsa-miR-4739	1	1	1
chr17:4085670\|4109863	hsa-miR-5192	1	1	1
chr17:4085670\|4109863	hsa-miR-6124	1	1	1
chr17:4085670\|4109863	hsa-miR-6131	1	1	1
chr17:4085670\|4109863	hsa-miR-29b-1-5p	1	1	1
chr17:4085670\|4109863	hsa-miR-134-3p	1	1	1
chr17:4085670\|4109863	hsa-miR-143-3p	1	1	1
chr17:4085670\|4109863	hsa-miR-504-3p	1	1	1
chr17:4085670\|4109863	hsa-miR-4433a-3p	1	1	1
chr17:4085670\|4109863	hsa-miR-671-5p	1	1	1
chr17:4085670\|4109863	hsa-miR-6894-5p	1	1	1
chr17:4085670\|4109863	hsa-miR-4687-3p	1	1	1
chr17:4085670\|4109863	hsa-miR-29b-2-5p	1	1	1
chr17:4085670\|4109863	hsa-miR-6728-5p	1	1	1
chr17:4085670\|4109863	hsa-miR-8071	1	1	1
chr17:4085670\|4109863	hsa-miR-766-5p	1	1	1
chr17:4085670\|4109863	hsa-miR-139-3p	1	1	1
chr17:4085670\|4109863	hsa-miR-5187-5p	1	1	1
chr17:4085670\|4109863	hsa-miR-4459	1	1	1
chr17:4085670\|4109863	hsa-miR-6890-5p	1	1	1
chr17:4085670\|4109863	hsa-miR-145-5p	1	1	1
chr17:4085670\|4109863	hsa-miR-6762-3p	1	1	1
chr17:4085670\|4109863	hsa-miR-3928-3p	1	1	1
chr17:4085670\|4109863	hsa-miR-8069	1	1	1
chr17:4085670\|4109863	hsa-miR-6873-3p	1	1	1
chr17:4085670\|4109863	hsa-miR-432-5p	1	1	1
chr17:4085670\|4109863	hsa-miR-7110-3p	1	1	1
chr17:4085670\|4109863	hsa-miR-6871-5p	1	1	1
chr17:4085670\|4109863	hsa-miR-185-3p	1	1	1
chr17:4085670\|4109863	hsa-miR-6829-5p	1	1	1
chr17:4085670\|4109863	hsa-miR-6760-5p	1	1	1
chr17:4085670\|4109863	hsa-miR-6850-5p	1	1	1
chr17:4085670\|4109863	hsa-miR-6772-3p	1	1	1
chr17:4085670\|4109863	hsa-miR-3127-5p	1	1	1
chr17:4085670\|4109863	hsa-miR-194-3p	1	1	1
chr17:4085670\|4109863	hsa-miR-4800-5p	1	1	1
chr17:4085670\|4109863	hsa-miR-593-3p	1	1	1
chr17:4085670\|4109863	hsa-miR-3681-5p	1	1	1
chr17:4085670\|4109863	hsa-miR-1238-3p	1	1	1
chr17:4085670\|4109863	hsa-miR-3664-3p	1	1	1
chr17:4085670\|4109863	hsa-miR-1229-3p	1	1	1

Target Genes

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Target miRNA Expression in different cancers

circRNA Open Reading Frame (ORF)

CircID	chr17:4085670\|4109863
ORF Type	ORF1
Protein Length	472
Nucleotide Length	1416
Protein Sequence	METNPAFVQTVLHNTQKALRHMPPLSLSPGSTDFSTFLSPNVLEEVDSFLIRITSCCSTPEVELTLLAFALARGSVAKVMSSLCTITDHLDTQYDASSLILSMASVRQNLLLKYGKPLQLTLQACDVKGKEDKSGPENLLVEPWTRDGFLTETGKTRASTIFSTGTESAFQVTQIRIMVRRGGIGAQCGLVFAYNSSSDKFCAEEHFKRFEKYDKWKLQELRQFVKSRIGCSSDDLGEDDPIGWFELEEEWDEADVKLQQCRVAKYLMVKFLCTRQESAERLGVQGLTISGYLRPARAEAEQSVTCAHCRKDTEESVCGATLLLRTLQFIQQLAHDLVQQKESGLKYKSFLDFAGLDLQIFWNFYSKLKQNPREECVSAQTLLLQLLQSCFSVLQGDVLAASEEEKAPIQSPKGVEAAKELYTHLCDVVDKVDGDSVPMEILKQEVRNTLLNGAAIFFPNRQTRRNHLFTMM
Nucleotide Sequence	ATGGAGACAAATCCCGCCTTTGTCCAGACAGTGCTGCACAATACTCAGAAGGCGCTGCGGCACATGCCTCCACTCTCTCTCTCACCAGGATCTACAGATTTCTCAACTTTCCTCTCCCCTAATGTGCTGGAAGAAGTGGACAGTTTCCTCATAAGGATAACTAGCTGCTGTTCTACCCCAGAGGTAGAACTGACTCTTCTGGCTTTTGCTCTCGCAAGAGGAAGTGTTGCCAAAGTCATGAGCTCTCTATGCACCATCACTGACCATCTGGACACGCAGTATGATGCCTCATCCCTCATCTTGTCCATGGCGTCAGTCAGACAGAACCTGCTCCTCAAATATGGTAAACCTCTCCAGTTGACTCTTCAGGCATGTGATGTCAAAGGAAAAGAAGATAAGTCTGGACCCGAAAACCTCCTTGTTGAACCGTGGACAAGGGATGGTTTTCTTACGGAAACTGGAAAAACCAGAGCCAGCACTATTTTTTCTACCGGAACTGAATCTGCCTTCCAAGTTACACAGATAAGAATTATGGTTCGACGTGGTGGCATTGGTGCCCAGTGTGGGTTGGTGTTTGCCTATAACTCATCTTCAGATAAATTTTGTGCGGAAGAACACTTCAAAAGGTTTGAAAAATATGACAAATGGAAGCTTCAGGAGCTCAGGCAATTTGTAAAAAGCAGGATTGGTTGCTCATCTGATGACCTTGGAGAGGATGATCCTATTGGCTGGTTTGAACTGGAAGAAGAATGGGATGAAGCAGATGTGAAGCTGCAACAGTGCAGAGTTGCCAAATATTTGATGGTGAAGTTCCTCTGCACCCGTCAGGAGTCAGCAGAGCGCTTGGGAGTGCAAGGCTTGACCATCAGTGGGTACCTCCGGCCTGCAAGAGCAGAAGCAGAACAGAGCGTCACCTGTGCACACTGCAGAAAGGACACAGAGGAGAGTGTCTGTGGGGCCACGTTGCTCCTCAGGACCCTTCAGTTTATCCAGCAGCTCGCCCATGACCTGGTGCAGCAGAAGGAAAGTGGCTTAAAATATAAATCTTTTCTGGACTTCGCGGGTCTTGATTTGCAGATCTTCTGGAATTTTTACAGTAAATTAAAGCAAAACCCGAGGGAAGAATGCGTCTCTGCCCAAACCCTGCTTCTGCAGCTACTCCAGAGCTGCTTCTCTGTGCTGCAGGGAGATGTACTGGCTGCTTCTGAGGAGGAAAAGGCTCCAATCCAAAGCCCTAAAGGAGTAGAGGCTGCCAAGGAGCTGTACACACACTTGTGTGATGTGGTGGACAAGGTGGATGGAGACTCTGTGCCCATGGAGATACTAAAACAAGAAGTCAGGAATACCCTTCTCAATGGGGCTGCCATCTTCTTTCCTAATCGACAGACCCGACGGAACCATCTCTTCACCATGATG

CircID	chr17:4085670\|4109863
ORF Type	ORF2
Protein Length	107
Nucleotide Length	321
Protein Sequence	MVKRWFRRVCRLGKKMAAPLRRVFLTSCFSISMGTESPSTLSTTSHKCVYSSLAASTPLGLWIGAFSSSEAASTSPCSTEKQLWSSCRSRVWAETHSSLGFCFNLL*
Nucleotide Sequence	ATGGTGAAGAGATGGTTCCGTCGGGTCTGTCGATTAGGAAAGAAGATGGCAGCCCCATTGAGAAGGGTATTCCTGACTTCTTGTTTTAGTATCTCCATGGGCACAGAGTCTCCATCCACCTTGTCCACCACATCACACAAGTGTGTGTACAGCTCCTTGGCAGCCTCTACTCCTTTAGGGCTTTGGATTGGAGCCTTTTCCTCCTCAGAAGCAGCCAGTACATCTCCCTGCAGCACAGAGAAGCAGCTCTGGAGTAGCTGCAGAAGCAGGGTTTGGGCAGAGACGCATTCTTCCCTCGGGTTTTGCTTTAATTTACTGTAA

CircID	chr17:4085670\|4109863
ORF Type	ORF3
Protein Length	88
Nucleotide Length	264
Protein Sequence	MDKMRDEASYCVSRWSVMVHRELMTLATLPLARAKARRVSSTSGVEQQLVILMRKLSTSSSTLGERKVEKSVDPGERESGGMCRSAF*
Nucleotide Sequence	ATGGACAAGATGAGGGATGAGGCATCATACTGCGTGTCCAGATGGTCAGTGATGGTGCATAGAGAGCTCATGACTTTGGCAACACTTCCTCTTGCGAGAGCAAAAGCCAGAAGAGTCAGTTCTACCTCTGGGGTAGAACAGCAGCTAGTTATCCTTATGAGGAAACTGTCCACTTCTTCCAGCACATTAGGGGAGAGGAAAGTTGAGAAATCTGTAGATCCTGGTGAGAGAGAGAGTGGAGGCATGTGCCGCAGCGCCTTCTGA

CircID	chr17:4085670\|4109863
ORF Type	ORF4
Protein Length	62
Nucleotide Length	186
Protein Sequence	MPPRRTIILICVTWKADSVPVEKIVLALVFPVSVRKPSLVHGSTRRFSGPDLSSFPLTSHA*
Nucleotide Sequence	ATGCCACCACGTCGAACCATAATTCTTATCTGTGTAACTTGGAAGGCAGATTCAGTTCCGGTAGAAAAAATAGTGCTGGCTCTGGTTTTTCCAGTTTCCGTAAGAAAACCATCCCTTGTCCACGGTTCAACAAGGAGGTTTTCGGGTCCAGACTTATCTTCTTTTCCTTTGACATCACATGCCTGA

CircID	chr17:4085670\|4109863
ORF Type	ORF5
Protein Length	58
Nucleotide Length	174
Protein Sequence	MGELLDKLKGPEEQRGPTDTLLCVLSAVCTGDALFCFCSCRPEVPTDGQALHSQALC*
Nucleotide Sequence	ATGGGCGAGCTGCTGGATAAACTGAAGGGTCCTGAGGAGCAACGTGGCCCCACAGACACTCTCCTCTGTGTCCTTTCTGCAGTGTGCACAGGTGACGCTCTGTTCTGCTTCTGCTCTTGCAGGCCGGAGGTACCCACTGATGGTCAAGCCTTGCACTCCCAAGCGCTCTGCTGA

CircID	chr17:4085670\|4109863
ORF Type	ORF6
Protein Length	54
Nucleotide Length	162
Protein Sequence	MVLVSADISGDGFYGDKSRLCPDSAAQYSEGAAAHASTLSLTRIYRFLNFPLP*
Nucleotide Sequence	ATGGTATTGGTCTCTGCTGACATCTCTGGTGACGGCTTCTATGGAGACAAATCCCGCCTTTGTCCAGACAGTGCTGCACAATACTCAGAAGGCGCTGCGGCACATGCCTCCACTCTCTCTCTCACCAGGATCTACAGATTTCTCAACTTTCCTCTCCCCTAA

CircID	chr17:4085670\|4109863
ORF Type	ORF7
Protein Length	50
Nucleotide Length	150
Protein Sequence	MSKEKKISLDPKTSLLNRGQGMVFLRKLEKPEPALFFLPELNLPSKLHR*
Nucleotide Sequence	ATGTCAAAGGAAAAGAAGATAAGTCTGGACCCGAAAACCTCCTTGTTGAACCGTGGACAAGGGATGGTTTTCTTACGGAAACTGGAAAAACCAGAGCCAGCACTATTTTTTCTACCGGAACTGAATCTGCCTTCCAAGTTACACAGATAA

CircID	chr17:4085670\|4109863
ORF Type	ORF8
Protein Length	37
Nucleotide Length	111
Protein Sequence	MAATLEFMVSGLLAFRELRSLGSQSQMLLQYGIGLC*
Nucleotide Sequence	ATGGCTGCGACACTAGAATTCATGGTCTCAGGGCTGTTGGCTTTCAGAGAGTTAAGAAGTCTGGGGTCTCAGTCTCAGATGCTTCTGCAATATGGTATTGGTCTCTGCTGA

CircID	chr17:4085670\|4109863
ORF Type	ORF9
Protein Length	80
Nucleotide Length	240
Protein Sequence	LEPFPPQKQPVHLPAAQRSSSGVAAEAGFGQRRILPSGFALIYCKNSRRSANQDPRSPEKIYILSHFPSAAPGHGRAAG*
Nucleotide Sequence	TTGGAGCCTTTTCCTCCTCAGAAGCAGCCAGTACATCTCCCTGCAGCACAGAGAAGCAGCTCTGGAGTAGCTGCAGAAGCAGGGTTTGGGCAGAGACGCATTCTTCCCTCGGGTTTTGCTTTAATTTACTGTAAAAATTCCAGAAGATCTGCAAATCAAGACCCGCGAAGTCCAGAAAAGATTTATATTTTAAGCCACTTTCCTTCTGCTGCACCAGGTCATGGGCGAGCTGCTGGATAA

CircID	chr17:4085670\|4109863
ORF Type	ORF10
Protein Length	76
Nucleotide Length	228
Protein Sequence	VQSCQIFDGEVPLHPSGVSRALGSARLDHQWVPPACKSRSRTERHLCTLQKGHRGECLWGHVAPQDPSVYPAARP*
Nucleotide Sequence	GTGCAGAGTTGCCAAATATTTGATGGTGAAGTTCCTCTGCACCCGTCAGGAGTCAGCAGAGCGCTTGGGAGTGCAAGGCTTGACCATCAGTGGGTACCTCCGGCCTGCAAGAGCAGAAGCAGAACAGAGCGTCACCTGTGCACACTGCAGAAAGGACACAGAGGAGAGTGTCTGTGGGGCCACGTTGCTCCTCAGGACCCTTCAGTTTATCCAGCAGCTCGCCCATGA

CircID	chr17:4085670\|4109863
ORF Type	ORF11
Protein Length	67
Nucleotide Length	201
Protein Sequence	LEGRFSSGRKNSAGSGFSSFRKKTIPCPRFNKEVFGSRLIFFSFDITCLKSQLERFTIFEEQVLSD*
Nucleotide Sequence	TTGGAAGGCAGATTCAGTTCCGGTAGAAAAAATAGTGCTGGCTCTGGTTTTTCCAGTTTCCGTAAGAAAACCATCCCTTGTCCACGGTTCAACAAGGAGGTTTTCGGGTCCAGACTTATCTTCTTTTCCTTTGACATCACATGCCTGAAGAGTCAACTGGAGAGGTTTACCATATTTGAGGAGCAGGTTCTGTCTGACTGA

CircID	chr17:4085670\|4109863
ORF Type	ORF12
Protein Length	56
Nucleotide Length	168
Protein Sequence	VQRNFTIKYLATLHCCSFTSASSHSSSSSNQPIGSSSPRSSDEQPILLFTNCLSS*
Nucleotide Sequence	GTGCAGAGGAACTTCACCATCAAATATTTGGCAACTCTGCACTGTTGCAGCTTCACATCTGCTTCATCCCATTCTTCTTCCAGTTCAAACCAGCCAATAGGATCATCCTCTCCAAGGTCATCAGATGAGCAACCAATCCTGCTTTTTACAAATTGCCTGAGCTCCTGA

RNA Binding Protein (RBP) of circRNA

CircID	RBP	Number of Upstream Sites	Number of Downstream Sites	Number of Circ Exons Sites
chr17:4085670\|4109863	KHSRP	3	0	0
chr17:4085670\|4109863	ELAVL1	3	3	3
chr17:4085670\|4109863	FAM120A	0	0	2
chr17:4085670\|4109863	CELF2	1	0	0
chr17:4085670\|4109863	PRPF8	2	3	0
chr17:4085670\|4109863	TAF15	0	1	0
chr17:4085670\|4109863	FMR1	2	1	9
chr17:4085670\|4109863	CPSF3	0	0	1
chr17:4085670\|4109863	FUS	2	0	0
chr17:4085670\|4109863	DGCR8	0	1	2
chr17:4085670\|4109863	CPSF7	1	0	0
chr17:4085670\|4109863	SRSF1	0	1	13
chr17:4085670\|4109863	NOP58	1	0	14
chr17:4085670\|4109863	U2AF1	0	0	4
chr17:4085670\|4109863	U2AF2	11	6	8
chr17:4085670\|4109863	SRSF9	0	0	1
chr17:4085670\|4109863	NOP56	1	0	0
chr17:4085670\|4109863	DDX54	0	0	39
chr17:4085670\|4109863	RBM10	1	1	0
chr17:4085670\|4109863	PTBP1	2	0	5
chr17:4085670\|4109863	HNRNPC	4	1	9
chr17:4085670\|4109863	TRA2A	0	0	4
chr17:4085670\|4109863	ZNF184	0	0	1
chr17:4085670\|4109863	DDX3X	4	0	1
chr17:4085670\|4109863	SMNDC1	0	0	2
chr17:4085670\|4109863	LIN28B	0	0	8
chr17:4085670\|4109863	RANGAP1	0	0	1
chr17:4085670\|4109863	FXR1	0	0	5
chr17:4085670\|4109863	FXR2	0	0	6
chr17:4085670\|4109863	SND1	0	0	2
chr17:4085670\|4109863	IGF2BP1	0	0	9
chr17:4085670\|4109863	IGF2BP3	0	0	4
chr17:4085670\|4109863	IGF2BP2	0	1	21
chr17:4085670\|4109863	NPM1	0	0	1
chr17:4085670\|4109863	FBL	0	0	5
chr17:4085670\|4109863	BUD13	0	0	5
chr17:4085670\|4109863	RBFOX2	0	0	1
chr17:4085670\|4109863	CNBP	1	0	0
chr17:4085670\|4109863	SLTM	0	0	1
chr17:4085670\|4109863	EIF4G2	0	0	1
chr17:4085670\|4109863	CSTF2T	1	0	8
chr17:4085670\|4109863	BCCIP	0	0	2
chr17:4085670\|4109863	RBM27	0	0	1
chr17:4085670\|4109863	XRN2	0	0	2
chr17:4085670\|4109863	HNRNPK	0	2	0
chr17:4085670\|4109863	ALKBH5	0	0	1
chr17:4085670\|4109863	AGO1	0	0	1
chr17:4085670\|4109863	EIF4A3	0	2	23
chr17:4085670\|4109863	AGO2	0	0	3

CircRNA Information