CircNet

General Information

circRNA Basic Information

CircID	chr22:41160642\|41173784
Strand	+
CircType	exon
Host Gene	ENSG00000100393.11;
Algorism	CIRI2;
Sequence	GTATCATTTCTGTGAGAAGTGTTTCAATGAGATCCAAGGGGAGAGCGTTTCTTTGGGGGATGACCCTTCCCAGCCTCAAACTACAATAAATAAAGAACAATTTTCCAAGAGAAAAAATGACACACTGGATCCTGAACTGTTTGTTGAATGTACAGAGTGCGGAAGAAAGATGCATCAGATCTGTGTCCTTCACCATGAGATCATCTGGCCTGCTGGATTCGTCTGTGATGGCTGTTTAAAGAAAAGTGCACGAACTAGGAAAGAAAATAAGTTTTCTGCTAAAACTGCTTTAATAGCACATGTATTAAAATTAGAATGATATGAAGATTAGCATGTTCCCTGCACTCATATGACATGTAAATCTGCAAAGTAGTGACTACTTTGGGTTGCCATCTACCAGACTTGGCACCTTTCTAGAGAATCGTGTGAATGACTTTCTGAGGCGACAGAATCACCCTGAGTCAGGAGAGGTCACTGTTAGAGTAGTTCATGCTTCTGACAAAACCGTGGAAGTAAAACCAGGCATGAAAGCAAGGTTTGTGGACAGTGGAGAGATGGCAGAATCCTTTCCATACCGAACCAAAGCCCTCTTTGCCTTTGAAGAAATTGATGGTGTTGACCTGTGCTTCTTTGGCATGCATGTTCAAGAGTATGGCTCTGACTGCCCTCCACCCAACCAGAGTCGGGTGGGAATTTCTTTTCTCCAAAAATAGTATAAAGGCAATAATAAAAACGTATAGGGATCACCAAATACTGATTGATGTGTATGTGCCAGGCACTGCTAGTTACTACAAATAGAAGGAAACCACAGGCTCACTGAACTTCCCTGAAGGGTTCACGGCGGAGTCGCCTACCTGCCTGTGATGAGCTTCACAAATAACGATGTGAGCAAAGAGCGAGAGTATACATATCTTACCTCGATAGTGTTCATTTCTTCCGTCCTAAATGCTTGAGGACTGCAGTCTATCATGAAATCCTAATTGGATATTTAGAATATGTCAAGAAATTAGGTTACACAACAGGGCATATTTGGGCATGTCCACCAAGTGAGGGAGATGATTATATCTTCCATTGCCATCCTCCTGACCAGAAGATACCCAAGCCCAAGCGACTGCAGGAATGGTACAAAAAAATGCTTGACAAGGCTGTATCAGAGCGTATTGTCCATGACTACAAGGATATTTTTAAACAAGCTACTGAAGATAGATTAACAAGTGCAAAGGAATTGCCTTATTTCGAGGGTGATTTCTGGCCCAATGTTCTGGAAGAAAGCATTAAGGAACTGGAACAGGAGGAAGAAGAGAGAAAACGAGAGGAAAACACCAGCAATGAAAGCACAGATGTGACCAAGGGAGACAGCAAAAATGCTAAAAAGAAGAATAATAAGAAAACCAGCAAAAATAAGAGCAGCCTGAGTAGGGGCAACAAGAAGAAACCCGGGATGCCCAATGTATCTAACGACCTCTCACAGAAACTATATGCCACCATGGAGAAGCATAAAGAG

circRNA Expression in different cancers

circRNA-miRNA-gene regulatory network

Target miRNAs

CircID	miRNA	PITA	miRanda	targetScan
chr22:41160642\|41173784	hsa-miR-718	1	1	1
chr22:41160642\|41173784	hsa-miR-3665	1	1	1
chr22:41160642\|41173784	hsa-miR-6124	1	1	1
chr22:41160642\|41173784	hsa-miR-6131	1	1	1
chr22:41160642\|41173784	hsa-miR-6165	1	1	1
chr22:41160642\|41173784	hsa-miR-7703	1	1	1
chr22:41160642\|41173784	hsa-miR-127-5p	1	1	1
chr22:41160642\|41173784	hsa-miR-138-5p	1	1	1
chr22:41160642\|41173784	hsa-miR-4433a-3p	1	1	1
chr22:41160642\|41173784	hsa-miR-1972	1	1	1
chr22:41160642\|41173784	hsa-miR-7114-5p	1	1	1
chr22:41160642\|41173784	hsa-miR-6515-5p	1	1	1
chr22:41160642\|41173784	hsa-miR-6880-5p	1	1	1
chr22:41160642\|41173784	hsa-miR-7847-3p	1	1	1
chr22:41160642\|41173784	hsa-miR-4459	1	1	1
chr22:41160642\|41173784	hsa-miR-6875-3p	1	1	1
chr22:41160642\|41173784	hsa-miR-6873-3p	1	1	1
chr22:41160642\|41173784	hsa-miR-432-5p	1	1	1
chr22:41160642\|41173784	hsa-miR-6868-3p	1	1	1
chr22:41160642\|41173784	hsa-miR-1229-5p	1	1	1
chr22:41160642\|41173784	hsa-miR-4640-5p	1	1	1
chr22:41160642\|41173784	hsa-miR-5001-3p	1	1	1
chr22:41160642\|41173784	hsa-miR-4690-5p	1	1	1
chr22:41160642\|41173784	hsa-miR-6821-3p	1	1	1
chr22:41160642\|41173784	hsa-miR-6818-3p	1	1	1
chr22:41160642\|41173784	hsa-miR-6809-3p	1	1	1
chr22:41160642\|41173784	hsa-miR-7111-3p	1	1	1
chr22:41160642\|41173784	hsa-miR-6780a-3p	1	1	1
chr22:41160642\|41173784	hsa-miR-6739-3p	1	1	1
chr22:41160642\|41173784	hsa-miR-1184	1	1	1
chr22:41160642\|41173784	hsa-miR-7152-3p	1	1	1
chr22:41160642\|41173784	hsa-miR-4661-3p	1	1	1
chr22:41160642\|41173784	hsa-miR-3944-5p	1	1	1
chr22:41160642\|41173784	hsa-miR-6801-5p	1	1	1
chr22:41160642\|41173784	hsa-miR-1245b-3p	1	1	1
chr22:41160642\|41173784	hsa-miR-214-3p	1	1	1
chr22:41160642\|41173784	hsa-miR-541-5p	1	1	1
chr22:41160642\|41173784	hsa-miR-6800-3p	1	1	1

Target Genes

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Target miRNA Expression in different cancers

circRNA Open Reading Frame (ORF)

CircID	chr22:41160642\|41173784
ORF Type	ORF1
Protein Length	185
Nucleotide Length	555
Protein Sequence	LRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESTDVTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKE
Nucleotide Sequence	TTGAGGACTGCAGTCTATCATGAAATCCTAATTGGATATTTAGAATATGTCAAGAAATTAGGTTACACAACAGGGCATATTTGGGCATGTCCACCAAGTGAGGGAGATGATTATATCTTCCATTGCCATCCTCCTGACCAGAAGATACCCAAGCCCAAGCGACTGCAGGAATGGTACAAAAAAATGCTTGACAAGGCTGTATCAGAGCGTATTGTCCATGACTACAAGGATATTTTTAAACAAGCTACTGAAGATAGATTAACAAGTGCAAAGGAATTGCCTTATTTCGAGGGTGATTTCTGGCCCAATGTTCTGGAAGAAAGCATTAAGGAACTGGAACAGGAGGAAGAAGAGAGAAAACGAGAGGAAAACACCAGCAATGAAAGCACAGATGTGACCAAGGGAGACAGCAAAAATGCTAAAAAGAAGAATAATAAGAAAACCAGCAAAAATAAGAGCAGCCTGAGTAGGGGCAACAAGAAGAAACCCGGGATGCCCAATGTATCTAACGACCTCTCACAGAAACTATATGCCACCATGGAGAAGCATAAAGAG

CircID	chr22:41160642\|41173784
ORF Type	ORF2
Protein Length	86
Nucleotide Length	258
Protein Sequence	MVAYSFCERSLDTLGIPGFFLLPLLRLLLFLLVFLLFFFLAFLLSPLVTSVLSLLVFSSRFLSSSSCSSSLMLSSRTLGQKSPSK*
Nucleotide Sequence	ATGGTGGCATATAGTTTCTGTGAGAGGTCGTTAGATACATTGGGCATCCCGGGTTTCTTCTTGTTGCCCCTACTCAGGCTGCTCTTATTTTTGCTGGTTTTCTTATTATTCTTCTTTTTAGCATTTTTGCTGTCTCCCTTGGTCACATCTGTGCTTTCATTGCTGGTGTTTTCCTCTCGTTTTCTCTCTTCTTCCTCCTGTTCCAGTTCCTTAATGCTTTCTTCCAGAACATTGGGCCAGAAATCACCCTCGAAATAA

CircID	chr22:41160642\|41173784
ORF Type	ORF3
Protein Length	65
Nucleotide Length	195
Protein Sequence	MVKDTDLMHLSSALCTFNKQFRIQCVIFSLGKLFFIYCSLRLGRVIPQRNALPLDLIETLLTEMI
Nucleotide Sequence	ATGGTGAAGGACACAGATCTGATGCATCTTTCTTCCGCACTCTGTACATTCAACAAACAGTTCAGGATCCAGTGTGTCATTTTTTCTCTTGGAAAATTGTTCTTTATTTATTGTAGTTTGAGGCTGGGAAGGGTCATCCCCCAAAGAAACGCTCTCCCCTTGGATCTCATTGAAACACTTCTCACAGAAATGATA

CircID	chr22:41160642\|41173784
ORF Type	ORF4
Protein Length	63
Nucleotide Length	189
Protein Sequence	MKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQSRVGISFLQK*
Nucleotide Sequence	ATGAAAGCAAGGTTTGTGGACAGTGGAGAGATGGCAGAATCCTTTCCATACCGAACCAAAGCCCTCTTTGCCTTTGAAGAAATTGATGGTGTTGACCTGTGCTTCTTTGGCATGCATGTTCAAGAGTATGGCTCTGACTGCCCTCCACCCAACCAGAGTCGGGTGGGAATTTCTTTTCTCCAAAAATAG

CircID	chr22:41160642\|41173784
ORF Type	ORF5
Protein Length	63
Nucleotide Length	189
Protein Sequence	MVLTCASLACMFKSMALTALHPTRVGWEFLFSKNSIKAIIKTYRDHQILIDVYVPGTASYYK*
Nucleotide Sequence	ATGGTGTTGACCTGTGCTTCTTTGGCATGCATGTTCAAGAGTATGGCTCTGACTGCCCTCCACCCAACCAGAGTCGGGTGGGAATTTCTTTTCTCCAAAAATAGTATAAAGGCAATAATAAAAACGTATAGGGATCACCAAATACTGATTGATGTGTATGTGCCAGGCACTGCTAGTTACTACAAATAG

CircID	chr22:41160642\|41173784
ORF Type	ORF6
Protein Length	60
Nucleotide Length	180
Protein Sequence	MHAKEAQVNTINFFKGKEGFGSVWKGFCHLSTVHKPCFHAWFYFHGFVRSMNYSNSDLS*
Nucleotide Sequence	ATGCATGCCAAAGAAGCACAGGTCAACACCATCAATTTCTTCAAAGGCAAAGAGGGCTTTGGTTCGGTATGGAAAGGATTCTGCCATCTCTCCACTGTCCACAAACCTTGCTTTCATGCCTGGTTTTACTTCCACGGTTTTGTCAGAAGCATGAACTACTCTAACAGTGACCTCTCCTGA

CircID	chr22:41160642\|41173784
ORF Type	ORF7
Protein Length	52
Nucleotide Length	156
Protein Sequence	MIISSIAILLTRRYPSPSDCRNGTKKCLTRLYQSVLSMTTRIFLNKLLKID*
Nucleotide Sequence	ATGATTATATCTTCCATTGCCATCCTCCTGACCAGAAGATACCCAAGCCCAAGCGACTGCAGGAATGGTACAAAAAAATGCTTGACAAGGCTGTATCAGAGCGTATTGTCCATGACTACAAGGATATTTTTAAACAAGCTACTGAAGATAGATTAA

CircID	chr22:41160642\|41173784
ORF Type	ORF8
Protein Length	50
Nucleotide Length	150
Protein Sequence	MPKKHRSTPSISSKAKRALVRYGKDSAISPLSTNLAFMPGFTSTVLSEA*
Nucleotide Sequence	ATGCCAAAGAAGCACAGGTCAACACCATCAATTTCTTCAAAGGCAAAGAGGGCTTTGGTTCGGTATGGAAAGGATTCTGCCATCTCTCCACTGTCCACAAACCTTGCTTTCATGCCTGGTTTTACTTCCACGGTTTTGTCAGAAGCATGA

CircID	chr22:41160642\|41173784
ORF Type	ORF9
Protein Length	50
Nucleotide Length	150
Protein Sequence	MHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKTALIAHVLKLE*
Nucleotide Sequence	ATGCATCAGATCTGTGTCCTTCACCATGAGATCATCTGGCCTGCTGGATTCGTCTGTGATGGCTGTTTAAAGAAAAGTGCACGAACTAGGAAAGAAAATAAGTTTTCTGCTAAAACTGCTTTAATAGCACATGTATTAAAATTAGAATGA

CircID	chr22:41160642\|41173784
ORF Type	ORF10
Protein Length	91
Nucleotide Length	273
Protein Sequence	LVIPIRFYYCLYTIFGEKKFPPDSGWVEGSQSHTLEHACQRSTGQHHQFLQRQRGLWFGMERILPSLHCPQTLLSCLVLLPRFCQKHELL*
Nucleotide Sequence	TTGGTGATCCCTATACGTTTTTATTATTGCCTTTATACTATTTTTGGAGAAAAGAAATTCCCACCCGACTCTGGTTGGGTGGAGGGCAGTCAGAGCCATACTCTTGAACATGCATGCCAAAGAAGCACAGGTCAACACCATCAATTTCTTCAAAGGCAAAGAGGGCTTTGGTTCGGTATGGAAAGGATTCTGCCATCTCTCCACTGTCCACAAACCTTGCTTTCATGCCTGGTTTTACTTCCACGGTTTTGTCAGAAGCATGAACTACTCTAA

CircID	chr22:41160642\|41173784
ORF Type	ORF11
Protein Length	41
Nucleotide Length	123
Protein Sequence	MTHWILNCLLNVQSAEERCIRSVSFTMRSSGLLDSSVMAV*
Nucleotide Sequence	ATGACACACTGGATCCTGAACTGTTTGTTGAATGTACAGAGTGCGGAAGAAAGATGCATCAGATCTGTGTCCTTCACCATGAGATCATCTGGCCTGCTGGATTCGTCTGTGATGGCTGTTTAA

CircID	chr22:41160642\|41173784
ORF Type	ORF12
Protein Length	40
Nucleotide Length	120
Protein Sequence	MIDCSPQAFRTEEMNTIEVRYVYSRSLLTSLFVKLITGR*
Nucleotide Sequence	ATGATAGACTGCAGTCCTCAAGCATTTAGGACGGAAGAAATGAACACTATCGAGGTAAGATATGTATACTCTCGCTCTTTGCTCACATCGTTATTTGTGAAGCTCATCACAGGCAGGTAG

CircID	chr22:41160642\|41173784
ORF Type	ORF13
Protein Length	86
Nucleotide Length	258
Protein Sequence	EVVRYIGHPGFLLVAPTQAALIFAGFLIILLFSIFAVSLGHICAFIAGVFLSFSLFFLLFQFLNAFFQNIGPEITLEIRQFLCTC*
Nucleotide Sequence	GAGGTCGTTAGATACATTGGGCATCCCGGGTTTCTTCTTGTTGCCCCTACTCAGGCTGCTCTTATTTTTGCTGGTTTTCTTATTATTCTTCTTTTTAGCATTTTTGCTGTCTCCCTTGGTCACATCTGTGCTTTCATTGCTGGTGTTTTCCTCTCGTTTTCTCTCTTCTTCCTCCTGTTCCAGTTCCTTAATGCTTTCTTCCAGAACATTGGGCCAGAAATCACCCTCGAAATAAGGCAATTCCTTTGCACTTGTTAA

CircID	chr22:41160642\|41173784
ORF Type	ORF14
Protein Length	30
Nucleotide Length	90
Protein Sequence	MFWKKALRNWNRRKKRENERKTPAMKAQM*
Nucleotide Sequence	ATGTTCTGGAAGAAAGCATTAAGGAACTGGAACAGGAGGAAGAAGAGAGAAAACGAGAGGAAAACACCAGCAATGAAAGCACAGATGTGA

CircID	chr22:41160642\|41173784
ORF Type	ORF15
Protein Length	30
Nucleotide Length	90
Protein Sequence	MSFTNNDVSKEREYTYLTSIVFISSVLNA*
Nucleotide Sequence	ATGAGCTTCACAAATAACGATGTGAGCAAAGAGCGAGAGTATACATATCTTACCTCGATAGTGTTCATTTCTTCCGTCCTAAATGCTTGA

RNA Binding Protein (RBP) of circRNA

CircID	RBP	Number of Upstream Sites	Number of Downstream Sites	Number of Circ Exons Sites
chr22:41160642\|41173784	U2AF2	17	8	5
chr22:41160642\|41173784	MOV10	0	0	2
chr22:41160642\|41173784	ELAVL1	5	4	7
chr22:41160642\|41173784	SF3B4	3	0	0
chr22:41160642\|41173784	FAM120A	0	0	2
chr22:41160642\|41173784	CELF2	3	0	0
chr22:41160642\|41173784	CNBP	0	0	1
chr22:41160642\|41173784	TAF15	0	1	0
chr22:41160642\|41173784	FMR1	0	0	28
chr22:41160642\|41173784	CPSF6	0	0	2
chr22:41160642\|41173784	GNL3	0	0	1
chr22:41160642\|41173784	DGCR8	1	1	1
chr22:41160642\|41173784	SRSF7	0	0	1
chr22:41160642\|41173784	SRSF1	0	1	2
chr22:41160642\|41173784	NOP58	0	0	15
chr22:41160642\|41173784	NOP56	0	4	1
chr22:41160642\|41173784	DDX54	0	0	28
chr22:41160642\|41173784	RBM10	5	0	0
chr22:41160642\|41173784	PCBP2	1	0	0
chr22:41160642\|41173784	SF3A3	1	0	0
chr22:41160642\|41173784	PTBP1	0	0	8
chr22:41160642\|41173784	HNRNPC	1	1	1
chr22:41160642\|41173784	TRA2A	0	0	6
chr22:41160642\|41173784	ZNF184	0	0	2
chr22:41160642\|41173784	HNRNPA1	0	1	0
chr22:41160642\|41173784	ZC3H7B	0	0	1
chr22:41160642\|41173784	LARP7	0	0	1
chr22:41160642\|41173784	MSI2	0	0	1
chr22:41160642\|41173784	ACIN1	0	0	14
chr22:41160642\|41173784	LIN28B	0	0	7
chr22:41160642\|41173784	FXR2	0	0	2
chr22:41160642\|41173784	SND1	0	0	1
chr22:41160642\|41173784	IGF2BP1	0	0	3
chr22:41160642\|41173784	BUD13	1	0	0
chr22:41160642\|41173784	IGF2BP3	0	0	7
chr22:41160642\|41173784	IGF2BP2	1	2	19
chr22:41160642\|41173784	FTO	1	0	0
chr22:41160642\|41173784	TARDBP	1	0	1
chr22:41160642\|41173784	GTF2F1	1	0	0
chr22:41160642\|41173784	PRPF8	0	4	1
chr22:41160642\|41173784	EIF4G2	0	0	2
chr22:41160642\|41173784	RBM47	0	0	2
chr22:41160642\|41173784	CSTF2T	0	0	7
chr22:41160642\|41173784	BCCIP	0	0	1
chr22:41160642\|41173784	DKC1	1	1	0
chr22:41160642\|41173784	HNRNPK	1	0	0
chr22:41160642\|41173784	FBL	1	1	15
chr22:41160642\|41173784	EIF4A3	0	3	19
chr22:41160642\|41173784	AGO2	0	0	11

CircRNA Information