CircNet

General Information

circRNA Basic Information

CircID	chr3:111953930\|111962312
Strand	+
CircType	exon
Host Gene	ENSG00000144824.19;
Algorism	CIRI2;find_circ;DCC;
Sequence	GCCCATCTGCCCCTAGGACAGAGTAACAGCTGTGGAAGTGTGCTCCCTCCCTCACTGGCAGCCATGGCCAAAGACTCAGAATCTCGGAGGATGCTCAGAGGATGATGGTGTAAGTATAAGCCTTAATCAGCACTGTTAATAGAACTGACAGCGTGAGTCGTGCAAAGAACTTTGAGAGGAGAGTTTAAAACAGAGAGCTGAGAAACTCAGCTTCTGAAGTTGGAATGGTTATTGGCTTTTGAACAACTTGTGAACTATTCCTTTGTCAGCTTTAGAATGAATGAAATCTTTGTCCTTTTGTTTTTTGTTAAATACAGGAAAGTCCATTCTTGAGTTTTTCTCTGTAAACTTGGATTTAATCTGAAACTGTGAACATCATACCTTGTTAATTTGCTATTGTAACTAACACCATCAATGAGTGCATGTTGGAAGTGTTGTATGTTTTTCCTGCCCCCTTGTCATCCTTTTTGATCTTGTATCTTTTTCCCTTTCTACAATCATTCTCCCTCTTCATTCCTGACTTGTCCTGTGCCCTCTTCTTCTGGCTGTGGACTGTCATTAGGAAGAATGAATTCCTCAGCAGGAGCAATTAGTAATTCCAAAAGTTCAAGTATCAAAGAGCACGGTGCTCTTTCTTTGATCTTCTTGGCTTCAAAACAAATTAGACCAAGGCCCAAGCTTCATAGGCAGATGTTTCTGGTTGCTGGCTTGTGTCTGTAGATGTTTAAGATTCAAAGACTGAAAAATGAGGCAAACTAACATATTTATGGCTCCTTCCTTAGGTTATAATCACCAACAGATGAGTGAAGGACACAGGCAGAAATCTGAATTTTATAACCGCACAGCATCTGAATCAAATGTCTACTTGAATAGTTTCCATTATCCAGATCACAGCTACAAGGACCAGGCCTTTGATACTCTGAGCCTCGATAGCTCTGATAGCATGGAGACCAGCATCTCTGCTTGCTCACCAGACAACATCTCTAG

circRNA Expression in different cancers

circRNA-miRNA-gene regulatory network

Target miRNAs

CircID	miRNA	miRanda	targetScan
chr3:111953930\|111962312	hsa-miR-127-5p	1	1
chr3:111953930\|111962312	hsa-miR-125b-2-3p	1	1
chr3:111953930\|111962312	hsa-miR-93-3p	1	1
chr3:111953930\|111962312	hsa-miR-181c-3p	1	1
chr3:111953930\|111962312	hsa-miR-148a-5p	1	1

Target Genes

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Target miRNA Expression in different cancers

circRNA Open Reading Frame (ORF)

CircID	chr3:111953930\|111962312
ORF Type	ORF1
Protein Length	80
Nucleotide Length	240
Protein Sequence	MRQTNIFMAPSLGYNHQQMSEGHRQKSEFYNRTASESNVYLNSFHYPDHSYKDQAFDTLSLDSSDSMETSISACSPDNIS
Nucleotide Sequence	ATGAGGCAAACTAACATATTTATGGCTCCTTCCTTAGGTTATAATCACCAACAGATGAGTGAAGGACACAGGCAGAAATCTGAATTTTATAACCGCACAGCATCTGAATCAAATGTCTACTTGAATAGTTTCCATTATCCAGATCACAGCTACAAGGACCAGGCCTTTGATACTCTGAGCCTCGATAGCTCTGATAGCATGGAGACCAGCATCTCTGCTTGCTCACCAGACAACATCTCT

CircID	chr3:111953930\|111962312
ORF Type	ORF2
Protein Length	58
Nucleotide Length	174
Protein Sequence	MTVHSQKKRAQDKSGMKRENDCRKGKRYKIKKDDKGAGKTYNTSNMHSLMVLVTIAN*
Nucleotide Sequence	ATGACAGTCCACAGCCAGAAGAAGAGGGCACAGGACAAGTCAGGAATGAAGAGGGAGAATGATTGTAGAAAGGGAAAAAGATACAAGATCAAAAAGGATGACAAGGGGGCAGGAAAAACATACAACACTTCCAACATGCACTCATTGATGGTGTTAGTTACAATAGCAAATTAA

CircID	chr3:111953930\|111962312
ORF Type	ORF3
Protein Length	57
Nucleotide Length	171
Protein Sequence	MLEVLYVFPAPLSSFLILYLFPFLQSFSLFIPDLSCALFFWLWTVIRKNEFLSRSN*
Nucleotide Sequence	ATGTTGGAAGTGTTGTATGTTTTTCCTGCCCCCTTGTCATCCTTTTTGATCTTGTATCTTTTTCCCTTTCTACAATCATTCTCCCTCTTCATTCCTGACTTGTCCTGTGCCCTCTTCTTCTGGCTGTGGACTGTCATTAGGAAGAATGAATTCCTCAGCAGGAGCAATTAG

CircID	chr3:111953930\|111962312
ORF Type	ORF4
Protein Length	51
Nucleotide Length	153
Protein Sequence	MNSSAGAISNSKSSSIKEHGALSLIFLASKQIRPRPKLHRQMFLVAGLCL*
Nucleotide Sequence	ATGAATTCCTCAGCAGGAGCAATTAGTAATTCCAAAAGTTCAAGTATCAAAGAGCACGGTGCTCTTTCTTTGATCTTCTTGGCTTCAAAACAAATTAGACCAAGGCCCAAGCTTCATAGGCAGATGTTTCTGGTTGCTGGCTTGTGTCTGTAG

CircID	chr3:111953930\|111962312
ORF Type	ORF5
Protein Length	37
Nucleotide Length	111
Protein Sequence	MLVCLIFQSLNLKHLQTQASNQKHLPMKLGPWSNLF*
Nucleotide Sequence	ATGTTAGTTTGCCTCATTTTTCAGTCTTTGAATCTTAAACATCTACAGACACAAGCCAGCAACCAGAAACATCTGCCTATGAAGCTTGGGCCTTGGTCTAATTTGTTTTGA

CircID	chr3:111953930\|111962312
ORF Type	ORF6
Protein Length	33
Nucleotide Length	99
Protein Sequence	MDFPVFNKKQKDKDFIHSKADKGIVHKLFKSQ*
Nucleotide Sequence	ATGGACTTTCCTGTATTTAACAAAAAACAAAAGGACAAAGATTTCATTCATTCTAAAGCTGACAAAGGAATAGTTCACAAGTTGTTCAAAAGCCAATAA

CircID	chr3:111953930\|111962312
ORF Type	ORF7
Protein Length	30
Nucleotide Length	90
Protein Sequence	MIVEREKDTRSKRMTRGQEKHTTLPTCTH*
Nucleotide Sequence	ATGATTGTAGAAAGGGAAAAAGATACAAGATCAAAAAGGATGACAAGGGGGCAGGAAAAACATACAACACTTCCAACATGCACTCATTGA

CircID	chr3:111953930\|111962312
ORF Type	ORF8
Protein Length	68
Nucleotide Length	204
Protein Sequence	QGGRKNIQHFQHALIDGVSYNSKLTRYDVHSFRLNPSLQRKTQEWTFLYLTKNKRTKISFILKLTKE*
Nucleotide Sequence	CAAGGGGGCAGGAAAAACATACAACACTTCCAACATGCACTCATTGATGGTGTTAGTTACAATAGCAAATTAACAAGGTATGATGTTCACAGTTTCAGATTAAATCCAAGTTTACAGAGAAAAACTCAAGAATGGACTTTCCTGTATTTAACAAAAAACAAAAGGACAAAGATTTCATTCATTCTAAAGCTGACAAAGGAATAG

CircID	chr3:111953930\|111962312
ORF Type	ORF9
Protein Length	60
Nucleotide Length	180
Protein Sequence	LGLGLICFEAKKIKERAPCSLILELLELLIAPAEEFILPNDSPQPEEEGTGQVRNEEGE*
Nucleotide Sequence	TTGGGCCTTGGTCTAATTTGTTTTGAAGCCAAGAAGATCAAAGAAAGAGCACCGTGCTCTTTGATACTTGAACTTTTGGAATTACTAATTGCTCCTGCTGAGGAATTCATTCTTCCTAATGACAGTCCACAGCCAGAAGAAGAGGGCACAGGACAAGTCAGGAATGAAGAGGGAGAATGA

RNA Binding Protein (RBP) of circRNA

CircID	RBP	Number of Upstream Sites	Number of Downstream Sites	Number of Circ Exons Sites
chr3:111953930\|111962312	SF3B4	1	0	0
chr3:111953930\|111962312	PRPF8	0	2	2
chr3:111953930\|111962312	TAF15	1	1	0
chr3:111953930\|111962312	SRSF1	3	0	1
chr3:111953930\|111962312	NOP58	0	0	1
chr3:111953930\|111962312	U2AF1	1	0	0
chr3:111953930\|111962312	U2AF2	13	4	5
chr3:111953930\|111962312	SRSF9	1	0	0
chr3:111953930\|111962312	PCBP2	0	0	2
chr3:111953930\|111962312	SF3A3	2	0	0
chr3:111953930\|111962312	HNRNPL	0	1	0
chr3:111953930\|111962312	PTBP1	0	0	2
chr3:111953930\|111962312	HNRNPC	0	1	0
chr3:111953930\|111962312	SMNDC1	1	0	0
chr3:111953930\|111962312	AUH	1	0	0
chr3:111953930\|111962312	MSI1	1	0	0
chr3:111953930\|111962312	ACIN1	0	1	2
chr3:111953930\|111962312	IGF2BP3	1	0	0
chr3:111953930\|111962312	IGF2BP2	0	1	3
chr3:111953930\|111962312	MBNL2	1	0	0
chr3:111953930\|111962312	TARDBP	0	0	1
chr3:111953930\|111962312	YTHDC1	1	0	0
chr3:111953930\|111962312	BUD13	1	0	1
chr3:111953930\|111962312	RBFOX2	2	0	0
chr3:111953930\|111962312	RBM47	0	0	1
chr3:111953930\|111962312	TIA1	0	1	0
chr3:111953930\|111962312	TIAL1	1	1	0
chr3:111953930\|111962312	EWSR1	1	0	0
chr3:111953930\|111962312	EIF4A3	5	3	10
chr3:111953930\|111962312	AGO2	0	0	1

CircRNA Information