CircNet

General Information

circRNA Basic Information

CircID	chr4:48684673\|48710698
Strand	-
CircType	exon
Host Gene	ENSG00000075539.13;
Algorism	find_circ;CIRI2;DCC;
Sequence	CCTAGAACATTCCATATTCTGCTTCACACACGGTGACTCACTCACTACTGCTTTGTACCAGTGTGCCCACTCGAGTGCCTGTAAAGTACAAGCTCCAGATCAAAAAAGCTTCTAGATGGATCCTTTCCAAACTTGGTGTCTTTTCTACAAACTCTGTGCCTCAACAACCATTTCTAAGTGATAAAATGTTCTCTGATCAAGTGGAATGAAAATAAAAATTAATCCCATGTTAAGTAATCCATATGGAGACAAGATGAAAAAGTGATTGTCCTGCAAGTAAACAGACGAAAAAGGTCCCAGAAAGACCCACCCCCACCAATCCAGCCCTGCTAAAAAGCTGAAGCCATTTATTGGTATCTTGGATGGTTAACATCTAAATGCTTAATTCCTGAAACCACTCAAGAGTCATAGGATTAGATGATCCAAGTCACCAAGAAATTACTGTCTCAAGTGATACG

circRNA Expression in different cancers

circRNA-miRNA-gene regulatory network

Target miRNAs

CircID	miRNA	PITA	miRanda	targetScan
chr4:48684673\|48710698	hsa-miR-224-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-224-3p	0	0	1
chr4:48684673\|48710698	hsa-miR-377-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-377-3p	0	0	1
chr4:48684673\|48710698	hsa-miR-335-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-335-3p	0	0	1
chr4:48684673\|48710698	hsa-miR-511-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-511-3p	0	0	1
chr4:48684673\|48710698	hsa-miR-432-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-432-3p	0	0	1
chr4:48684673\|48710698	hsa-miR-519e-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-519e-3p	0	0	1
chr4:48684673\|48710698	hsa-miR-558	0	0	1
chr4:48684673\|48710698	hsa-miR-559	0	0	1
chr4:48684673\|48710698	hsa-miR-587	0	0	1
chr4:48684673\|48710698	hsa-miR-640	0	0	1
chr4:48684673\|48710698	hsa-miR-648	0	0	1
chr4:48684673\|48710698	hsa-miR-543	0	0	1
chr4:48684673\|48710698	hsa-miR-1200	0	0	1
chr4:48684673\|48710698	hsa-miR-548j-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-548j-3p	0	0	1
chr4:48684673\|48710698	hsa-miR-548k	0	0	1
chr4:48684673\|48710698	hsa-miR-548l	0	0	1
chr4:48684673\|48710698	hsa-miR-513c-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-513c-3p	0	0	1
chr4:48684673\|48710698	hsa-miR-1283	0	0	1
chr4:48684673\|48710698	hsa-miR-199a-5p	0	1	1
chr4:48684673\|48710698	hsa-miR-501-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-576-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-199b-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-518d-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-519b-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-519c-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-520c-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-515-3p	0	0	1
chr4:48684673\|48710698	hsa-miR-548b-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-548d-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-548c-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-548a-5p	0	0	1
chr4:48684673\|48710698	hsa-miR-548i	0	0	1
chr4:48684673\|48710698	hsa-miR-550	0	0	1
chr4:48684673\|48710698	hsa-miR-526a	0	0	1
chr4:48684673\|48710698	hsa-miR-548h	0	0	1
chr4:48684673\|48710698	hsa-miR-1193	0	1	0
chr4:48684673\|48710698	hsa-miR-8054	0	1	0
chr4:48684673\|48710698	hsa-miR-145-3p	0	1	0
chr4:48684673\|48710698	hsa-miR-127-3p	0	1	0
chr4:48684673\|48710698	hsa-miR-6889-3p	0	1	0
chr4:48684673\|48710698	hsa-miR-3680-5p	0	1	0
chr4:48684673\|48710698	hsa-miR-3664-5p	0	1	0
chr4:48684673\|48710698	hsa-miR-1271-3p	0	1	0
chr4:48684673\|48710698	hsa-miR-550a-3-5p	0	1	0
chr4:48684673\|48710698	hsa-miR-550a-5p	1	1	0
chr4:48684673\|48710698	hsa-miR-485-3p	1	0	0
chr4:48684673\|48710698	hsa-miR-33b-3p	0	1	0
chr4:48684673\|48710698	hsa-miR-433-5p	0	1	0
chr4:48684673\|48710698	hsa-miR-510-3p	0	1	0

Target Genes

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Target miRNA Expression in different cancers

circRNA Open Reading Frame (ORF)

CircID	chr4:48684673\|48710698
ORF Type	ORF1
Protein Length	48
Nucleotide Length	144
Protein Sequence	MLTIQDTNKWLQLFSRAGLVGVGLSGTFFVCLLAGQSLFHLVSIWIT*
Nucleotide Sequence	ATGTTAACCATCCAAGATACCAATAAATGGCTTCAGCTTTTTAGCAGGGCTGGATTGGTGGGGGTGGGTCTTTCTGGGACCTTTTTCGTCTGTTTACTTGCAGGACAATCACTTTTTCATCTTGTCTCCATATGGATTACTTAA

CircID	chr4:48684673\|48710698
ORF Type	ORF2
Protein Length	59
Nucleotide Length	177
Protein Sequence	VTHSLLLCTSVPTRVPVKYKLQIKKASRWILSKLGVFSTNSVPQQPFLSDKMFSDQVE*
Nucleotide Sequence	GTGACTCACTCACTACTGCTTTGTACCAGTGTGCCCACTCGAGTGCCTGTAAAGTACAAGCTCCAGATCAAAAAAGCTTCTAGATGGATCCTTTCCAAACTTGGTGTCTTTTCTACAAACTCTGTGCCTCAACAACCATTTCTAAGTGATAAAATGTTCTCTGATCAAGTGGAATGA

CircID	chr4:48684673\|48710698
ORF Type	ORF1
Protein Length	40
Nucleotide Length	123
Protein Sequence	MLRHRVCRKDTKFGKDPSRSFFDLELVLYRHSSGHTGTKQ
Nucleotide Sequence	TTGTTGAGGCACAGAGTTTGTAGAAAAGACACCAAGTTTGGAAAGGATCCATCTAGAAGCTTTTTTGATCTGGAGCTTGTACTTTACAGGCACTCGAGTGGGCACACTGGTACAAAGCAGTAG

CircID	chr4:48684673\|48710698
ORF Type	ORF2
Protein Length	30
Nucleotide Length	93
Protein Sequence	MERIHLEAFLIWSLYFTGTRVGTLVQSSSE
Nucleotide Sequence	TTGGAAAGGATCCATCTAGAAGCTTTTTTGATCTGGAGCTTGTACTTTACAGGCACTCGAGTGGGCACACTGGTACAAAGCAGTAGTGAGTGA

CircID	chr4:48684673\|48710698
ORF Type	ORF3
Protein Length	55
Nucleotide Length	168
Protein Sequence	MLCTSVPTRVPVKYKLQIKKASRWILSKLGVFSTNSVPQQPFLSELKPFIGILDG
Nucleotide Sequence	CTGCTTTGTACCAGTGTGCCCACTCGAGTGCCTGTAAAGTACAAGCTCCAGATCAAAAAAGCTTCTAGATGGATCCTTTCCAAACTTGGTGTCTTTTCTACAAACTCTGTGCCTCAACAACCATTTCTAAGTGAGCTGAAGCCATTTATTGGTATCTTGGATGGTTAA

RNA Binding Protein (RBP) of circRNA

CircID	RBP	Number of Upstream Sites	Number of Downstream Sites	Number of Circ Exons Sites
chr4:48684673\|48710698	RBFOX2	1	2	0
chr4:48684673\|48710698	NOP58	0	2	2
chr4:48684673\|48710698	FBL	0	1	0
chr4:48684673\|48710698	HNRNPA1	0	3	0
chr4:48684673\|48710698	U2AF2	3	5	0
chr4:48684673\|48710698	CELF2	0	2	0
chr4:48684673\|48710698	NOP56	0	1	0
chr4:48684673\|48710698	CNBP	0	1	0
chr4:48684673\|48710698	FXR2	0	0	1
chr4:48684673\|48710698	HNRNPK	0	1	0
chr4:48684673\|48710698	PTBP1	1	0	1
chr4:48684673\|48710698	IGF2BP2	0	0	9
chr4:48684673\|48710698	AGO2	0	0	1
chr4:48684673\|48710698	EIF4A3	1	2	4
chr4:48684673\|48710698	FUS	0	1	1

CircRNA Information