CircNet

General Information

circRNA Basic Information

CircID	chr4:76996425\|77020670
Strand	+
CircType	exon
Host Gene	ENSG00000138758.11;
Algorism	find_circ;CIRI2;DCC;
Sequence	AATGAAGAGCTTCGAAACTTGTCTTTGTCTGGCCATGTGGGATTTGACAGCCTCCCTGACCAGCTGGTCAACAAGTCTACTTCTCAAGGATTCTGTTTCAACATCCTTTGTGTTGGTGAGACAGGCATTGGCAAATCCACGTTAATGGACACTTTGTTCAACACCAAATTTGAAAGTGACCCAGCTACTCACAATGAACCAGGTGTTCGGTTAAAAGCCAGAAGTTATGAGCTTCAGGAAAGCAATGTACGGCTGAAGTTAACCATTGTTGACACCGTGGGATTTGGAGACCAGATAAATAAAGATGACAGCTATAAGCCGATAGTAGAATATATTGATGCCCAGTTCGAGGCCTACCTGCAAGAGGAATTGAAGATTAAACGTTCTCTCTTCAACTACCATGACACGAGGATCCATGCCTGCCTCTACTTTATTGCCCCTACTGGACATTCACTAAAGTCCCTGGATCTGGTCACCATGAAAAAGCTGGACAGTAAGGTGAACATCATTCCAATAATTGCAAAAGCTGACACCATTGCCAAGAATGAACTGCACAAATTCAAGAGTAAGATCATGAGTGAACTGGTCAGCAATGGGGTCCAGATATATCAGTTTCCCACTGATGAAGAAACGGTGGCAGAGATTAACGCAACAATGAGTGTCCATCTCCCATTTGCAGTGGTTGGCAGCACCGAAGAGGTGAAGATTGGCAACAAGATGGCAAAGGCCAGGCAGTACCCCTGGGGTGTGGTGCAGGTTGAGAATGAAAATCATTGCGATTTTGTGAAACTTCGAGAGATGCTGATCCGCGTGAACATGGAGGACTTGCGAGAGCAGACTCACACCCGCCACTATGAATTGTACCGACGCTGTAAGCTTGAAGAGATGGGGTTCAAGGACACTGACCCTGACAGCAAACCCTTCAG

circRNA Expression in different cancers

circRNA-miRNA-gene regulatory network

Target miRNAs

CircID	miRNA	miRanda	targetScan
chr4:76996425\|77020670	hsa-miR-127-5p	1	1
chr4:76996425\|77020670	hsa-miR-214-5p	1	1
chr4:76996425\|77020670	hsa-miR-182-5p	1	1

Target Genes

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Target miRNA Expression in different cancers

circRNA Open Reading Frame (ORF)

CircID	chr4:76996425\|77020670
ORF Type	ORF1
Protein Length	260
Nucleotide Length	780
Protein Sequence	MDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPF
Nucleotide Sequence	ATGGACACTTTGTTCAACACCAAATTTGAAAGTGACCCAGCTACTCACAATGAACCAGGTGTTCGGTTAAAAGCCAGAAGTTATGAGCTTCAGGAAAGCAATGTACGGCTGAAGTTAACCATTGTTGACACCGTGGGATTTGGAGACCAGATAAATAAAGATGACAGCTATAAGCCGATAGTAGAATATATTGATGCCCAGTTCGAGGCCTACCTGCAAGAGGAATTGAAGATTAAACGTTCTCTCTTCAACTACCATGACACGAGGATCCATGCCTGCCTCTACTTTATTGCCCCTACTGGACATTCACTAAAGTCCCTGGATCTGGTCACCATGAAAAAGCTGGACAGTAAGGTGAACATCATTCCAATAATTGCAAAAGCTGACACCATTGCCAAGAATGAACTGCACAAATTCAAGAGTAAGATCATGAGTGAACTGGTCAGCAATGGGGTCCAGATATATCAGTTTCCCACTGATGAAGAAACGGTGGCAGAGATTAACGCAACAATGAGTGTCCATCTCCCATTTGCAGTGGTTGGCAGCACCGAAGAGGTGAAGATTGGCAACAAGATGGCAAAGGCCAGGCAGTACCCCTGGGGTGTGGTGCAGGTTGAGAATGAAAATCATTGCGATTTTGTGAAACTTCGAGAGATGCTGATCCGCGTGAACATGGAGGACTTGCGAGAGCAGACTCACACCCGCCACTATGAATTGTACCGACGCTGTAAGCTTGAAGAGATGGGGTTCAAGGACACTGACCCTGACAGCAAACCCTTC

CircID	chr4:76996425\|77020670
ORF Type	ORF2
Protein Length	107
Nucleotide Length	321
Protein Sequence	MIFILNLHHTPGVLPGLCHLVANLHLFGAANHCKWEMDTHCCVNLCHRFFISGKLIYLDPIADQFTHDLTLEFVQFILGNGVSFCNYWNDVHLTVQLFHGDQIQGL*
Nucleotide Sequence	ATGATTTTCATTCTCAACCTGCACCACACCCCAGGGGTACTGCCTGGCCTTTGCCATCTTGTTGCCAATCTTCACCTCTTCGGTGCTGCCAACCACTGCAAATGGGAGATGGACACTCATTGTTGCGTTAATCTCTGCCACCGTTTCTTCATCAGTGGGAAACTGATATATCTGGACCCCATTGCTGACCAGTTCACTCATGATCTTACTCTTGAATTTGTGCAGTTCATTCTTGGCAATGGTGTCAGCTTTTGCAATTATTGGAATGATGTTCACCTTACTGTCCAGCTTTTTCATGGTGACCAGATCCAGGGACTTTAG

CircID	chr4:76996425\|77020670
ORF Type	ORF3
Protein Length	64
Nucleotide Length	192
Protein Sequence	MSSRGNKVEAGMDPRVMVVEERTFNLQFLLQVGLELGINIFYYRLIAVIFIYLVSKSHGVNNG*
Nucleotide Sequence	ATGTCCAGTAGGGGCAATAAAGTAGAGGCAGGCATGGATCCTCGTGTCATGGTAGTTGAAGAGAGAACGTTTAATCTTCAATTCCTCTTGCAGGTAGGCCTCGAACTGGGCATCAATATATTCTACTATCGGCTTATAGCTGTCATCTTTATTTATCTGGTCTCCAAATCCCACGGTGTCAACAATGGTTAA

CircID	chr4:76996425\|77020670
ORF Type	ORF4
Protein Length	50
Nucleotide Length	150
Protein Sequence	MILLLNLCSSFLAMVSAFAIIGMMFTLLSSFFMVTRSRDFSECPVGAIK*
Nucleotide Sequence	ATGATCTTACTCTTGAATTTGTGCAGTTCATTCTTGGCAATGGTGTCAGCTTTTGCAATTATTGGAATGATGTTCACCTTACTGTCCAGCTTTTTCATGGTGACCAGATCCAGGGACTTTAGTGAATGTCCAGTAGGGGCAATAAAGTAG

CircID	chr4:76996425\|77020670
ORF Type	ORF5
Protein Length	48
Nucleotide Length	144
Protein Sequence	MKSFETCLCLAMWDLTASLTSWSTSLLLKDSVSTSFVLVRQALANPR*
Nucleotide Sequence	ATGAAGAGCTTCGAAACTTGTCTTTGTCTGGCCATGTGGGATTTGACAGCCTCCCTGACCAGCTGGTCAACAAGTCTACTTCTCAAGGATTCTGTTTCAACATCCTTTGTGTTGGTGAGACAGGCATTGGCAAATCCACGTTAA

CircID	chr4:76996425\|77020670
ORF Type	ORF6
Protein Length	64
Nucleotide Length	192
Protein Sequence	SSIPLAGRPRTGHQYILLSAYSCHLYLSGLQIPRCQQWLTSAVHCFPEAHNFWLLTEHLVHCE*
Nucleotide Sequence	TCTTCAATTCCTCTTGCAGGTAGGCCTCGAACTGGGCATCAATATATTCTACTATCGGCTTATAGCTGTCATCTTTATTTATCTGGTCTCCAAATCCCACGGTGTCAACAATGGTTAACTTCAGCCGTACATTGCTTTCCTGAAGCTCATAACTTCTGGCTTTTAACCGAACACCTGGTTCATTGTGAGTAG

RNA Binding Protein (RBP) of circRNA

CircID	RBP	Number of Upstream Sites	Number of Downstream Sites	Number of Circ Exons Sites
chr4:76996425\|77020670	NOP56	1	1	2
chr4:76996425\|77020670	ELAVL1	2	2	5
chr4:76996425\|77020670	SF3B4	2	0	0
chr4:76996425\|77020670	PRPF8	3	5	2
chr4:76996425\|77020670	UPF1	1	0	0
chr4:76996425\|77020670	SRSF10	1	0	0
chr4:76996425\|77020670	TNRC6A	0	0	1
chr4:76996425\|77020670	CAPRIN1	0	0	1
chr4:76996425\|77020670	FMR1	2	0	20
chr4:76996425\|77020670	CPSF3	0	1	0
chr4:76996425\|77020670	FUS	5	5	0
chr4:76996425\|77020670	DGCR8	1	2	3
chr4:76996425\|77020670	SRSF7	0	0	1
chr4:76996425\|77020670	SRSF1	1	0	4
chr4:76996425\|77020670	NOP58	2	1	10
chr4:76996425\|77020670	U2AF1	2	1	3
chr4:76996425\|77020670	ADAR	0	3	0
chr4:76996425\|77020670	U2AF2	4	5	3
chr4:76996425\|77020670	SRSF9	0	0	1
chr4:76996425\|77020670	DDX54	2	1	26
chr4:76996425\|77020670	EIF3G	1	0	0
chr4:76996425\|77020670	HNRNPM	1	1	0
chr4:76996425\|77020670	SF3A3	1	0	0
chr4:76996425\|77020670	FIP1L1	0	1	0
chr4:76996425\|77020670	PTBP1	4	5	3
chr4:76996425\|77020670	HNRNPC	4	3	2
chr4:76996425\|77020670	HNRNPD	1	0	0
chr4:76996425\|77020670	TRA2A	1	1	8
chr4:76996425\|77020670	ZNF184	0	1	1
chr4:76996425\|77020670	HNRNPA1	0	3	0
chr4:76996425\|77020670	DDX3X	2	0	4
chr4:76996425\|77020670	XRN2	0	1	0
chr4:76996425\|77020670	LARP4B	0	0	1
chr4:76996425\|77020670	ACIN1	0	0	1
chr4:76996425\|77020670	LIN28B	1	0	7
chr4:76996425\|77020670	FXR1	0	1	6
chr4:76996425\|77020670	FXR2	0	0	9
chr4:76996425\|77020670	SND1	0	0	4
chr4:76996425\|77020670	GTF2F1	0	1	0
chr4:76996425\|77020670	IGF2BP3	0	2	2
chr4:76996425\|77020670	IGF2BP2	5	6	22
chr4:76996425\|77020670	TARDBP	3	2	2
chr4:76996425\|77020670	TAF15	1	1	0
chr4:76996425\|77020670	BUD13	2	1	4
chr4:76996425\|77020670	RBM47	0	0	4
chr4:76996425\|77020670	EIF4G2	0	0	5
chr4:76996425\|77020670	DDX42	1	0	0
chr4:76996425\|77020670	CSTF2T	1	0	4
chr4:76996425\|77020670	NONO	1	0	0
chr4:76996425\|77020670	RBM22	0	1	0
chr4:76996425\|77020670	TIAL1	1	0	0
chr4:76996425\|77020670	AGO2	2	0	8
chr4:76996425\|77020670	EIF4A3	5	3	14
chr4:76996425\|77020670	FBL	0	0	9

CircRNA Information