miRTarBase - #MIRT620091 -
pre-miRNA Information
pre-miRNA hsa-mir-122   
Genomic Coordinates chr18: 58451074 - 58451158
Synonyms MIR122A, MIRN122, MIRN122A, hsa-mir-122, miRNA122, miRNA122A, MIR122
Description Homo sapiens miR-122 stem-loop
Comment The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-122-5p
Sequence 15| UGGAGUGUGACAAUGGUGUUUG |36
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 4 18 + 58451091 29233923 MiREDiBase
C-to-U 11 18 + 58451098 28550310 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1258166649 1 dbSNP
rs1426570658 6 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles

Circulating MicroRNA Expression Profiling
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol YME1L1   
Synonyms FTSH, MEG4, OPA11, PAMP, YME1L
Description YME1 like 1 ATPase
Transcript NM_014263   
Other Transcripts NM_139312   
Expression
Putative miRNA Targets on YME1L1
3'UTR of YME1L1
(miRNA target sites are highlighted)
>YME1L1|NM_014263|3'UTR
   1 TAACTCTCTTGATATGGATGCTTGCTGGTTTTATTGCAAGAATACAAGTAGCATTGCAGTAGTCTACTTTTACAACGCTT
  81 TCCCCTCATTCTTGATGTGGTGTAATTGAAGGGTGTGAAATGCTTTGTCAATCATTTGTCACATTTATCCAGTTTGGGTT
 161 ATTCTCATTATGACACCTATTGCAAATTAGCATCCCATGGCAAATATATTTTGAAAAAATAAAGAACTATCAGGATTGAA
 241 AACAGCTCTTTTGAGGAATGTCAATTAGTTATTAAGTTGAAAGTAATTAATGATTTTATGTTTGGTTACTCTACTAGATT
 321 TGATAAAAATTGTGCCTTTAGCCTTCTATATACATCAGTGGAAACTTAAGATGCAGTAATTATGTTCCAGATTGACCATG
 401 AATAAAATATTTTTTAATCTAAATGTAGAGAAGTTGGGATTAAAAGCAGTCTCGGAAACACAGAGCCAGGAATATAGCCT
 481 TTTGGCATGGTGCCATGGCTCACATCTGTAATCCCAGCACTTTTGGAGGCTGAGGCGGGTGGATTGCTTGAGGCCAGGAG
 561 TTCGAGACCAGCCTGGCCAACGTGGTGAAACGCTGTCTCTACTAAAATACAAAAAAATAGGGCTGGGCGCGGTTGCTCAC
 641 GCCTGTAATCCCAGCACTTTTCAGAGGCCAAGGCGGGCAAATCACCTGAGGTCAAGAGTTTGAGACCAGCCTGGCCAACA
 721 TGGTGAAACCCCATCTCTACTAAACATGCAAAAATTACCTGGGCATGGTGGCAGGTGCTTATAATCCCAGCTACTCTGGG
 801 GGCCAAGGCAGGAGAATTGCTTGAGCCTGGGAGATGGAGGTTGCAGTGAGCTGAGATCATGCCACTGCACTCCAGCCTGG
 881 GCAACAGAGCAAGACTCTGCCTCAAAAAAAAATTAAAATAAATTTAAATACAAAAAAAAATAGCCAGGTGTGGGGTGCAT
 961 GCCTGGAATCCCAGCTACTTGAGAGGCTGAGGCACGAGAATTGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGA
1041 TCACAGGAGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCTGTCTCAAAAAAAAATTAAATAAATTATTATAACC
1121 TTTCAGAAATGCTGTGTGCATTTTCATGTTCTTTTTTTTAGCATTACTGTCACTCTCCCTAATGAAATGTACTTCAGAGA
1201 AGCAGTATTTTGTTAAATAAATACATAACCTCATTCTGAATAATGTCCCTCATTTTGACTATAACTGTGCTTGGTTTCAA
1281 AAGCAAAATTAAACAAAAATCTCAGTCCCCTCCGAAGTGAACTTTGTGTTACCCTGCGTCAGAAATGCCAAGTTGTGTTT
1361 ACTTTTCATTCAGATTTTGTGAATATGAACATGCTGTTATAGGATCTACAGATGAATATTTAACTCAATAGAAAAATTAT
1441 TTTAGAACACATTGTATTGGTATTACAACCAGATTATATTCTTGACGTTGACTTCATTAAAATTATCTACAATTTCCTAA
1521 TAATTTAAGCTGTATATGGTCTTCATTGAAAAAAGATAGATATTGTTACAGGAAGCTTGTTACATTATATTCTTGACCTT
1601 TTGGTTGATAATCTTAAATCTTAATGTAATTTCAAACTGGCAGAAATGTTGCCAGCATAATACATGGATGTCTCATATAC
1681 CCTGCATCCAGATTTACCAGTTGTTATCATTCTGCCCGTTTTTTATTGCCCCAAACCTGTTCTGTCTCCCTCTCTGTATG
1761 TACATACATACACGTATAAAATATTGATAAAGTCTTATCTGTCTTAAATTTTTTTACATATTTGTTGAGGTATAATTTAC
1841 ATATGATAAAATTCATTTTAAATGTAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions (Predicted by miRanda)
IDDuplex structurePositionScoreMFE
1
miRNA  3' guUUGUGGUAACAGUGUGAGGu 5'
            |:||::| |||||| |||| 
Target 5' ttAGCATTACTGTCACTCTCCc 3'
1158 - 1179 148.00 -19.80
2
miRNA  3' guuUGUGGUAACAGUGUGAGGu 5'
             |::||| |   :|||||| 
Target 5' atcATGCCACT---GCACTCCa 3'
856 - 874 136.00 -13.60
3
miRNA  3' guuugUGGUAACAGUGUGAGGu 5'
               :||| |   :|||||| 
Target 5' caggaGCCACT---GCACTCCa 3'
1044 - 1062 130.00 -16.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30186403 6 COSMIC
COSN31507128 8 COSMIC
COSN31576377 31 COSMIC
COSN18735250 51 COSMIC
COSN31597824 77 COSMIC
COSN30514784 83 COSMIC
COSN30450587 84 COSMIC
COSN31586971 91 COSMIC
COSN30147620 108 COSMIC
COSN30744152 164 COSMIC
COSN31594953 185 COSMIC
COSN30494393 192 COSMIC
COSN30108805 197 COSMIC
COSN30119171 200 COSMIC
COSN30109840 207 COSMIC
COSN19692779 245 COSMIC
COSN15063755 292 COSMIC
COSN23712366 532 COSMIC
COSN29610086 903 COSMIC
COSN15382306 1101 COSMIC
COSN19370901 1827 COSMIC
COSN23394269 1859 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1353711002 2 dbSNP
rs774948359 5 dbSNP
rs372643666 6 dbSNP
rs771306278 8 dbSNP
rs1289878820 10 dbSNP
rs749672706 14 dbSNP
rs117518425 15 dbSNP
rs761196682 16 dbSNP
rs781363362 17 dbSNP
rs755135572 18 dbSNP
rs747010042 19 dbSNP
rs972714917 20 dbSNP
rs1487162412 24 dbSNP
rs780070492 25 dbSNP
rs758202433 27 dbSNP
rs1451302118 35 dbSNP
rs1313073946 36 dbSNP
rs537167844 40 dbSNP
rs1243906546 43 dbSNP
rs9833 45 dbSNP
rs757110240 48 dbSNP
rs990450618 51 dbSNP
rs1278321917 52 dbSNP
rs1418417039 54 dbSNP
rs558362373 55 dbSNP
rs1376956657 59 dbSNP
rs763812795 61 dbSNP
rs1466366449 62 dbSNP
rs760266097 63 dbSNP
rs763366731 66 dbSNP
rs1464231311 70 dbSNP
rs773714686 71 dbSNP
rs1171286873 73 dbSNP
rs763429309 76 dbSNP
rs1319949067 77 dbSNP
rs1338191290 77 dbSNP
rs773704254 80 dbSNP
rs762144404 83 dbSNP
rs1462060244 84 dbSNP
rs776859533 87 dbSNP
rs41282202 88 dbSNP
rs747115958 91 dbSNP
rs779938525 94 dbSNP
rs1229061463 97 dbSNP
rs772175527 102 dbSNP
rs201488273 106 dbSNP
rs778960693 109 dbSNP
rs1384765473 110 dbSNP
rs757163645 112 dbSNP
rs753648531 113 dbSNP
rs758495001 114 dbSNP
rs777575733 114 dbSNP
rs755668104 115 dbSNP
rs1205936530 117 dbSNP
rs752385557 123 dbSNP
rs535007166 128 dbSNP
rs759055844 131 dbSNP
rs750979852 143 dbSNP
rs765685897 145 dbSNP
rs1179991389 151 dbSNP
rs780312971 167 dbSNP
rs1042792629 169 dbSNP
rs997742808 173 dbSNP
rs1160092552 175 dbSNP
rs1483078675 176 dbSNP
rs1413583844 179 dbSNP
rs1253960594 181 dbSNP
rs1312919600 194 dbSNP
rs945372905 198 dbSNP
rs966696890 206 dbSNP
rs1017591807 207 dbSNP
rs1324129112 222 dbSNP
rs1007580795 224 dbSNP
rs756258177 231 dbSNP
rs1240137712 232 dbSNP
rs1277527462 239 dbSNP
rs1281664649 243 dbSNP
rs3758438 245 dbSNP
rs549711028 246 dbSNP
rs1056456765 249 dbSNP
rs937876573 251 dbSNP
rs191101370 253 dbSNP
rs41282200 254 dbSNP
rs1037280634 259 dbSNP
rs746552203 260 dbSNP
rs930563249 264 dbSNP
rs1173941116 268 dbSNP
rs1335071483 277 dbSNP
rs949292822 282 dbSNP
rs1427189543 284 dbSNP
rs917844437 291 dbSNP
rs1471173017 292 dbSNP
rs779920577 295 dbSNP
rs1392512823 298 dbSNP
rs1170550209 317 dbSNP
rs1331257215 319 dbSNP
rs1054704404 322 dbSNP
rs550674915 333 dbSNP
rs1477153927 340 dbSNP
rs139799744 353 dbSNP
rs1350333818 360 dbSNP
rs972177977 373 dbSNP
rs1226204630 374 dbSNP
rs925029846 380 dbSNP
rs879000681 390 dbSNP
rs979185212 411 dbSNP
rs1197530820 412 dbSNP
rs546698059 427 dbSNP
rs1442005670 433 dbSNP
rs966869813 436 dbSNP
rs965682685 449 dbSNP
rs1018732436 453 dbSNP
rs1254364588 459 dbSNP
rs1167374217 474 dbSNP
rs181519151 475 dbSNP
rs1462925533 478 dbSNP
rs953082196 479 dbSNP
rs1461579944 483 dbSNP
rs564922613 484 dbSNP
rs1028910350 487 dbSNP
rs1389025834 488 dbSNP
rs1440544287 495 dbSNP
rs1327015037 496 dbSNP
rs966292779 501 dbSNP
rs1341470320 504 dbSNP
rs1294910823 510 dbSNP
rs1001009242 513 dbSNP
rs147349217 517 dbSNP
rs4749227 518 dbSNP
rs1009549005 520 dbSNP
rs748986474 521 dbSNP
rs1214036979 524 dbSNP
rs1274849247 531 dbSNP
rs559180877 537 dbSNP
rs189982973 538 dbSNP
rs1407269028 539 dbSNP
rs1054216681 540 dbSNP
rs993564563 557 dbSNP
rs897909527 560 dbSNP
rs1408704429 563 dbSNP
rs573667716 564 dbSNP
rs1168523387 568 dbSNP
rs563366934 573 dbSNP
rs896386711 578 dbSNP
rs138697144 581 dbSNP
rs1288575727 585 dbSNP
rs1362924279 591 dbSNP
rs4749226 592 dbSNP
rs1354699739 597 dbSNP
rs924915467 598 dbSNP
rs780471192 601 dbSNP
rs1043786465 610 dbSNP
rs1214631059 618 dbSNP
rs764986203 618 dbSNP
rs1185632804 629 dbSNP
rs557976172 630 dbSNP
rs1445530778 631 dbSNP
rs1237336992 636 dbSNP
rs945121710 640 dbSNP
rs930490374 641 dbSNP
rs919191024 645 dbSNP
rs535180914 651 dbSNP
rs1273656444 664 dbSNP
rs572568998 675 dbSNP
rs556069528 686 dbSNP
rs781318824 696 dbSNP
rs1455566410 710 dbSNP
rs536184177 732 dbSNP
rs755035090 733 dbSNP
rs953258495 749 dbSNP
rs1374979856 766 dbSNP
rs1415309305 768 dbSNP
rs751620368 777 dbSNP
rs925720070 778 dbSNP
rs972494450 782 dbSNP
rs1348566077 783 dbSNP
rs980051104 786 dbSNP
rs1375772136 787 dbSNP
rs1307473374 788 dbSNP
rs968227972 789 dbSNP
rs567255465 791 dbSNP
rs1338012941 796 dbSNP
rs1021654420 800 dbSNP
rs1485748841 801 dbSNP
rs1212404914 805 dbSNP
rs1260156050 825 dbSNP
rs1482373559 826 dbSNP
rs1176943964 832 dbSNP
rs1405346174 835 dbSNP
rs1009787624 845 dbSNP
rs1421086240 846 dbSNP
rs371212669 847 dbSNP
rs960922373 850 dbSNP
rs1034988274 858 dbSNP
rs1165622832 865 dbSNP
rs1435350405 870 dbSNP
rs1314859419 873 dbSNP
rs1024832815 878 dbSNP
rs1013415445 885 dbSNP
rs1379930595 886 dbSNP
rs550636393 897 dbSNP
rs1298510112 899 dbSNP
rs1175216972 902 dbSNP
rs1384707012 912 dbSNP
rs1033481663 913 dbSNP
rs896355473 913 dbSNP
rs550919429 914 dbSNP
rs1306236600 918 dbSNP
rs1204500212 923 dbSNP
rs1233805932 929 dbSNP
rs1481863347 934 dbSNP
rs1002036930 939 dbSNP
rs1207223401 941 dbSNP
rs1252550563 941 dbSNP
rs1454891677 941 dbSNP
rs1471056343 942 dbSNP
rs1409284796 943 dbSNP
rs903797672 955 dbSNP
rs1002151574 963 dbSNP
rs1449850360 966 dbSNP
rs1456141961 974 dbSNP
rs766922737 986 dbSNP
rs536744003 987 dbSNP
rs995107226 992 dbSNP
rs540926473 995 dbSNP
rs1283483392 996 dbSNP
rs1036172399 1011 dbSNP
rs910691863 1012 dbSNP
rs763565330 1015 dbSNP
rs911776624 1020 dbSNP
rs373505309 1025 dbSNP
rs376847194 1027 dbSNP
rs1272984799 1030 dbSNP
rs931665629 1031 dbSNP
rs117419561 1032 dbSNP
rs2480716 1037 dbSNP
rs1360088057 1044 dbSNP
rs12247435 1045 dbSNP
rs10829185 1047 dbSNP
rs1408422692 1049 dbSNP
rs988230697 1064 dbSNP
rs960953371 1065 dbSNP
rs1035231403 1069 dbSNP
rs1033450450 1073 dbSNP
rs1002182672 1075 dbSNP
rs1395007317 1075 dbSNP
rs1491331021 1077 dbSNP
rs903766525 1077 dbSNP
rs1491490230 1078 dbSNP
rs1271455919 1084 dbSNP
rs1364653560 1087 dbSNP
rs1232048003 1098 dbSNP
rs11015537 1100 dbSNP
rs1336001149 1101 dbSNP
rs1487660686 1101 dbSNP
rs1009233691 1111 dbSNP
rs1446656610 1113 dbSNP
rs1216537021 1114 dbSNP
rs1243954688 1116 dbSNP
rs1239914548 1117 dbSNP
rs768218027 1118 dbSNP
rs1187205125 1121 dbSNP
rs541871884 1126 dbSNP
rs563330055 1137 dbSNP
rs181618870 1152 dbSNP
rs760194560 1153 dbSNP
rs528180056 1154 dbSNP
rs1050556730 1160 dbSNP
rs189272390 1163 dbSNP
rs770546925 1172 dbSNP
rs1008730504 1173 dbSNP
rs184997769 1182 dbSNP
rs1312729762 1188 dbSNP
rs1285786144 1190 dbSNP
rs920852428 1191 dbSNP
rs370743602 1205 dbSNP
rs1350185441 1208 dbSNP
rs1339907274 1220 dbSNP
rs1037053445 1221 dbSNP
rs1050317823 1225 dbSNP
rs1484770865 1227 dbSNP
rs1433144284 1229 dbSNP
rs1346013280 1245 dbSNP
rs774986975 1247 dbSNP
rs1486625067 1248 dbSNP
rs1333191594 1256 dbSNP
rs150116466 1261 dbSNP
rs1431217408 1270 dbSNP
rs1392880172 1273 dbSNP
rs1433491665 1282 dbSNP
rs746003741 1298 dbSNP
rs1376549766 1300 dbSNP
rs1177047502 1301 dbSNP
rs992806897 1303 dbSNP
rs904202810 1307 dbSNP
rs1043091259 1314 dbSNP
rs980555826 1319 dbSNP
rs945819636 1325 dbSNP
rs1233597844 1326 dbSNP
rs1236558283 1333 dbSNP
rs559274827 1337 dbSNP
rs988307574 1338 dbSNP
rs1349930149 1340 dbSNP
rs1194059253 1341 dbSNP
rs1009865106 1344 dbSNP
rs956655768 1349 dbSNP
rs1183734810 1352 dbSNP
rs141502663 1354 dbSNP
rs1250696980 1355 dbSNP
rs939502558 1362 dbSNP
rs1265441742 1371 dbSNP
rs1193678922 1372 dbSNP
rs1396410162 1375 dbSNP
rs1468017368 1377 dbSNP
rs1019005180 1379 dbSNP
rs1204850870 1379 dbSNP
rs1396418295 1396 dbSNP
rs1307486361 1400 dbSNP
rs1333818747 1400 dbSNP
rs1008583253 1401 dbSNP
rs888856157 1407 dbSNP
rs1293438151 1411 dbSNP
rs556030860 1415 dbSNP
rs994994054 1428 dbSNP
rs1283789026 1429 dbSNP
rs981059984 1429 dbSNP
rs1250630125 1437 dbSNP
rs1450795511 1438 dbSNP
rs970018882 1440 dbSNP
rs1197290342 1448 dbSNP
rs1271079323 1456 dbSNP
rs148345658 1457 dbSNP
rs545498270 1470 dbSNP
rs1254328618 1471 dbSNP
rs973776271 1479 dbSNP
rs940916371 1482 dbSNP
rs778861197 1485 dbSNP
rs116622573 1486 dbSNP
rs749057940 1487 dbSNP
rs1015015475 1490 dbSNP
rs1173236328 1508 dbSNP
rs1008761565 1510 dbSNP
rs781434511 1512 dbSNP
rs978850407 1514 dbSNP
rs968839944 1517 dbSNP
rs1028803697 1519 dbSNP
rs1294982619 1522 dbSNP
rs1326919408 1529 dbSNP
rs1220447615 1541 dbSNP
rs1291195712 1546 dbSNP
rs1333977012 1548 dbSNP
rs1410072089 1564 dbSNP
rs1412493842 1565 dbSNP
rs755156881 1579 dbSNP
rs956806215 1580 dbSNP
rs1261870172 1586 dbSNP
rs904399994 1592 dbSNP
rs537009315 1595 dbSNP
rs1475048935 1599 dbSNP
rs953057374 1612 dbSNP
rs1028669809 1618 dbSNP
rs994953962 1619 dbSNP
rs898932319 1620 dbSNP
rs1036909364 1624 dbSNP
rs781435835 1625 dbSNP
rs1480558251 1634 dbSNP
rs1250147622 1636 dbSNP
rs1310923586 1647 dbSNP
rs1207296275 1655 dbSNP
rs192191520 1668 dbSNP
rs75444919 1670 dbSNP
rs891569694 1678 dbSNP
rs1056794329 1680 dbSNP
rs1260792289 1682 dbSNP
rs1043041387 1684 dbSNP
rs938405465 1689 dbSNP
rs1208112430 1690 dbSNP
rs928154655 1691 dbSNP
rs913331482 1695 dbSNP
rs780264631 1701 dbSNP
rs143360619 1704 dbSNP
rs1299782081 1706 dbSNP
rs948336362 1706 dbSNP
rs920835433 1708 dbSNP
rs189588318 1715 dbSNP
rs1348780285 1717 dbSNP
rs962022348 1718 dbSNP
rs987350641 1725 dbSNP
rs1171873243 1732 dbSNP
rs1374730567 1735 dbSNP
rs1385485907 1736 dbSNP
rs1028637282 1739 dbSNP
rs141418676 1741 dbSNP
rs973105754 1742 dbSNP
rs1390461249 1744 dbSNP
rs1418833042 1748 dbSNP
rs529060561 1750 dbSNP
rs963444315 1752 dbSNP
rs1472025091 1756 dbSNP
rs1015047964 1757 dbSNP
rs1279037972 1758 dbSNP
rs1347760101 1764 dbSNP
rs1179454333 1768 dbSNP
rs1258129080 1771 dbSNP
rs544551319 1773 dbSNP
rs73598020 1774 dbSNP
rs1220368519 1786 dbSNP
rs7477806 1789 dbSNP
rs906143776 1795 dbSNP
rs377501077 1798 dbSNP
rs548559971 1801 dbSNP
rs781288296 1808 dbSNP
rs947441909 1809 dbSNP
rs1461249033 1811 dbSNP
rs968699298 1815 dbSNP
rs1314884996 1816 dbSNP
rs1438317276 1816 dbSNP
rs1308954705 1818 dbSNP
rs146649115 1824 dbSNP
rs754189037 1840 dbSNP
rs1220455872 1841 dbSNP
rs1053248836 1846 dbSNP
rs1300677781 1854 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084079. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_AbnovaAb HITS-CLIP data was present in GSM1084065. RNA binding protein: AGO2. Condition:CLIP_emetine_AbnovaAb HITS-CLIP data was present in GSM1084064. RNA binding protein: AGO2. Condition:CLIP_noemetine_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084064
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_AbnovaAb
Location of target site ENST00000326799.3 | 3UTR | CACAGGAGCCACUGCACUCCAGCCUGGGUGAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084065
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_AbnovaAb
Location of target site ENST00000326799.3 | 3UTR | CAGGAGCCACUGCACUCCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1084079
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_AbnovaAb
Location of target site ENST00000326799.3 | 3UTR | CACAGGAGCCACUGCACUCCAGCCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer -0.761 7.9e-6 -0.712 4.8e-5 24 Click to see details
GSE27834 Pluripotent stem cells 0.392 6.7e-2 0.324 1.1e-1 16 Click to see details
GSE21687 Ependynoma primary tumors -0.17 9.0e-2 -0.063 3.1e-1 64 Click to see details
GSE28260 Renal cortex and medulla 0.386 9.6e-2 0.418 7.8e-2 13 Click to see details
GSE19350 CNS germ cell tumors -0.387 1.1e-1 0.024 4.7e-1 12 Click to see details
GSE21849 B cell lymphoma 0.223 1.2e-1 0.445 7.8e-3 29 Click to see details
GSE35602 Colorectal cancer stromal tissue -0.224 1.4e-1 -0.223 1.4e-1 25 Click to see details
GSE42095 Differentiated embryonic stem cells -0.222 1.5e-1 -0.403 2.8e-2 23 Click to see details
GSE38226 Liver fibrosis 0.222 1.7e-1 0.263 1.2e-1 21 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.197 1.7e-1 -0.248 1.2e-1 25 Click to see details
GSE26953 Aortic valvular endothelial cells 0.182 2.0e-1 0.180 2.0e-1 24 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.389 2.2e-1 0.657 7.8e-2 6 Click to see details
GSE17306 Multiple myeloma -0.096 2.6e-1 -0.021 4.4e-1 49 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.101 3.4e-1 -0.137 2.8e-1 20 Click to see details
GSE32688 Pancreatic cancer 0.029 4.4e-1 0.162 1.9e-1 32 Click to see details
GSE17498 Multiple myeloma 0.014 4.7e-1 -0.175 1.4e-1 40 Click to see details
GSE14794 Lymphoblastoid cells 0.009 4.7e-1 0.033 3.8e-1 90 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
KIRC 0.349 0.03 0.256 0.09 29 Click to see details
KIRP -0.426 0.13 -0.033 0.47 9 Click to see details
KICH -0.399 0.16 -0.333 0.21 8 Click to see details
ESCA 0.44 0.23 0.600 0.14 5 Click to see details
STAD 0.242 0.28 0.333 0.21 8 Click to see details
HNSC -0.597 0.3 -0.500 0.33 3 Click to see details
THCA 0.304 0.31 0.600 0.14 5 Click to see details
LIHC -0.034 0.41 -0.299 0.02 49 Click to see details
CHOL 0.064 0.44 0.200 0.3 9 Click to see details
CHOL 0.064 0.44 0.200 0.3 9 Click to see details
CHOL 0.064 0.44 0.200 0.3 9 Click to see details
CHOL 0.064 0.44 0.200 0.3 9 Click to see details
CHOL 0.064 0.44 0.200 0.3 9 Click to see details
CHOL 0.064 0.44 0.200 0.3 9 Click to see details
MiRNA Regulatory Network:
Functional analysis:
Strong evidence (reporter assay, western blot, qRT-PCR or qPCR) Other evidence
Transcription factor regulation Circular RNA sponge
534 hsa-miR-122-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT000012 CYP7A1 cytochrome P450 family 7 subfamily A member 1 3 1
MIRT006421 WNT1 Wnt family member 1 3 1
MIRT000364 IGF1R insulin like growth factor 1 receptor 4 3
MIRT000365 SRF serum response factor 4 1
MIRT000663 RAC1 Rac family small GTPase 1 5 2
MIRT000717 RHOA ras homolog family member A 2 2
MIRT006123 PRKRA protein activator of interferon induced protein kinase EIF2AK2 4 1
MIRT003006 CCNG1 cyclin G1 4 4
MIRT003081 ANK2 ankyrin 2 3 1
MIRT003082 NFATC2IP nuclear factor of activated T-cells 2 interacting protein 3 1
MIRT003083 ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 3 1
MIRT003084 ANXA11 annexin A11 4 2
MIRT003085 ALDOA aldolase, fructose-bisphosphate A 3 2
MIRT003086 RAB6B RAB6B, member RAS oncogene family 3 1
MIRT003087 RAB11FIP1 RAB11 family interacting protein 1 4 2
MIRT003088 FOXP1 forkhead box P1 3 1
MIRT003089 MECP2 methyl-CpG binding protein 2 3 2
MIRT003090 NCAM1 neural cell adhesion molecule 1 4 3
MIRT003091 UBAP2 ubiquitin associated protein 2 3 1
MIRT003092 TBX19 T-box 19 3 1
MIRT003093 AACS acetoacetyl-CoA synthetase 3 1
MIRT003094 DUSP2 dual specificity phosphatase 2 3 1
MIRT003095 ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 3 1
MIRT003097 MAPK11 mitogen-activated protein kinase 11 3 1
MIRT003098 FUNDC2 FUN14 domain containing 2 3 1
MIRT003099 AKT3 AKT serine/threonine kinase 3 3 3
MIRT003100 TPD52L2 tumor protein D52 like 2 4 3
MIRT003102 GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 4 2
MIRT003103 G6PC3 glucose-6-phosphatase catalytic subunit 3 4 2
MIRT003104 AP3M2 adaptor related protein complex 3 mu 2 subunit 3 1
MIRT003105 SLC7A1 solute carrier family 7 member 1 4 4
MIRT003106 XPO6 exportin 6 3 1
MIRT003107 FOXJ3 forkhead box J3 3 1
MIRT003108 SLC7A11 solute carrier family 7 member 11 3 1
MIRT003109 TRIB1 tribbles pseudokinase 1 3 1
MIRT003110 EGLN3 egl-9 family hypoxia inducible factor 3 3 1
MIRT003111 NUMBL NUMB like, endocytic adaptor protein 3 1
MIRT003112 ADAM17 ADAM metallopeptidase domain 17 3 5
MIRT003727 DSTYK dual serine/threonine and tyrosine protein kinase 3 2
MIRT003728 FAM117B family with sequence similarity 117 member B 3 1
MIRT004364 BCL2L2 BCL2 like 2 4 2
MIRT004527 PRKAB1 protein kinase AMP-activated non-catalytic subunit beta 1 2 1
MIRT004879 ADAM10 ADAM metallopeptidase domain 10 4 1
MIRT005782 ACVR1C activin A receptor type 1C 1 1
MIRT007007 PTPN1 protein tyrosine phosphatase, non-receptor type 1 1 1
MIRT007081 NT5C3A 5'-nucleotidase, cytosolic IIIA 1 1
MIRT007082 P4HA1 prolyl 4-hydroxylase subunit alpha 1 1 1
MIRT007083 ZNF395 zinc finger protein 395 1 1
MIRT007084 SOCS1 suppressor of cytokine signaling 1 1 1
MIRT023396 PKM pyruvate kinase, muscle 5 3
MIRT023398 CLIC4 chloride intracellular channel 4 4 4
MIRT023403 CDK4 cyclin dependent kinase 4 2 2
MIRT438005 MEF2D myocyte enhancer factor 2D 1 2
MIRT438639 AXL AXL receptor tyrosine kinase 1 1
MIRT438655 NOD2 nucleotide binding oligomerization domain containing 2 3 1
MIRT438734 FUT8 fucosyltransferase 8 3 1
MIRT003079 GTF2B general transcription factor IIB 2 1
MIRT003080 GYS1 glycogen synthase 1 4 2
MIRT023217 SSR3 signal sequence receptor subunit 3 1 1
MIRT023218 PHOX2A paired like homeobox 2a 1 1
MIRT023219 DZIP1L DAZ interacting zinc finger protein 1 like 1 1
MIRT023220 GSTM2 glutathione S-transferase mu 2 1 1
MIRT023221 RAI14 retinoic acid induced 14 1 1
MIRT023222 STARD13 StAR related lipid transfer domain containing 13 1 1
MIRT023223 CNN3 calponin 3 1 1
MIRT023224 A2M alpha-2-macroglobulin 1 1
MIRT023225 EFCAB6 EF-hand calcium binding domain 6 1 1
MIRT023226 GLOD4 glyoxalase domain containing 4 1 1
MIRT023227 CALR calreticulin 1 1
MIRT023228 POFUT1 protein O-fucosyltransferase 1 1 1
MIRT023229 PYGO1 pygopus family PHD finger 1 1 1
MIRT023230 CDY2B chromodomain Y-linked 2B 1 1
MIRT023231 CDC42EP3 CDC42 effector protein 3 1 1
MIRT023232 CS citrate synthase 2 2
MIRT023233 RNF170 ring finger protein 170 2 2
MIRT023234 GTF3C6 general transcription factor IIIC subunit 6 1 1
MIRT023235 ZNF321P zinc finger protein 321, pseudogene 1 1
MIRT023236 LAMP1 lysosomal associated membrane protein 1 1 1
MIRT023237 SLC52A2 solute carrier family 52 member 2 1 1
MIRT023238 ZNF658 zinc finger protein 658 1 1
MIRT023239 ATP13A3 ATPase 13A3 1 1
MIRT023240 CPNE5 copine 5 1 1
MIRT023241 KATNAL1 katanin catalytic subunit A1 like 1 1 1
MIRT023242 TMEM136 transmembrane protein 136 1 1
MIRT023243 ATP11A ATPase phospholipid transporting 11A 1 1
MIRT023244 TMEM74 transmembrane protein 74 1 1
MIRT023245 ANKRD10 ankyrin repeat domain 10 1 1
MIRT023246 TBL1XR1 transducin beta like 1 X-linked receptor 1 1 1
MIRT023247 USP10 ubiquitin specific peptidase 10 1 1
MIRT023248 AKAP11 A-kinase anchoring protein 11 1 1
MIRT023249 BACH2 BTB domain and CNC homolog 2 1 1
MIRT023250 HCCS holocytochrome c synthase 1 1
MIRT023251 Slc7a1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 1 1
MIRT023252 GTDC2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) 1 1
MIRT023253 CTPS1 CTP synthase 1 1 1
MIRT023254 SLC44A1 solute carrier family 44 member 1 1 1
MIRT023255 CLSPN claspin 1 1
MIRT023256 RABGEF1 RAB guanine nucleotide exchange factor 1 1 1
MIRT023257 FBXO7 F-box protein 7 1 1
MIRT023258 NCDN neurochondrin 1 1
MIRT023259 SOX2 SRY-box 2 1 1
MIRT023260 ZNF618 zinc finger protein 618 1 1
MIRT023261 ABLIM1 actin binding LIM protein 1 1 1
MIRT023262 ZBTB4 zinc finger and BTB domain containing 4 1 1
MIRT023263 LUZP1 leucine zipper protein 1 1 1
MIRT023264 NLGN3 neuroligin 3 1 1
MIRT023265 PRR11 proline rich 11 1 1
MIRT023266 HHAT hedgehog acyltransferase 1 1
MIRT023267 UBE2L3 ubiquitin conjugating enzyme E2 L3 1 1
MIRT023268 DNAJC18 DnaJ heat shock protein family (Hsp40) member C18 1 1
MIRT023269 FAM102A family with sequence similarity 102 member A 1 1
MIRT023270 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 1 1
MIRT023271 DENND2C DENN domain containing 2C 1 1
MIRT023272 HMOX1 heme oxygenase 1 3 2
MIRT023273 USP28 ubiquitin specific peptidase 28 1 1
MIRT023274 KRT18 keratin 18 1 1
MIRT023275 BPGM bisphosphoglycerate mutase 1 1
MIRT023276 ZNF233 zinc finger protein 233 1 1
MIRT023277 SLC25A30 solute carrier family 25 member 30 1 1
MIRT023278 ANKRD9 ankyrin repeat domain 9 2 2
MIRT023279 RLN1 relaxin 1 1 1
MIRT023280 DDIT3 DNA damage inducible transcript 3 1 1
MIRT023281 TRIM65 tripartite motif containing 65 1 1
MIRT023282 B4GALT1 beta-1,4-galactosyltransferase 1 1 1
MIRT023283 ANXA7 annexin A7 1 1
MIRT023284 SLC19A2 solute carrier family 19 member 2 1 1
MIRT023285 MARCKS myristoylated alanine rich protein kinase C substrate 1 1
MIRT023286 CLEC11A C-type lectin domain containing 11A 1 1
MIRT023287 CENPF centromere protein F 1 1
MIRT023288 CLDN18 claudin 18 1 1
MIRT023289 PFDN1 prefoldin subunit 1 1 1
MIRT023290 SPAG9 sperm associated antigen 9 1 1
MIRT023291 CEACAM8 carcinoembryonic antigen related cell adhesion molecule 8 1 1
MIRT023292 KRT10 keratin 10 1 1
MIRT023293 SET SET nuclear proto-oncogene 1 1
MIRT023294 SLC11A2 solute carrier family 11 member 2 1 1
MIRT023295 MYCBP MYC binding protein 2 2
MIRT023296 GPHB5 glycoprotein hormone beta 5 1 1
MIRT023297 STAU2 staufen double-stranded RNA binding protein 2 1 1
MIRT023298 NFATC1 nuclear factor of activated T-cells 1 1 1
MIRT023299 ERP29 endoplasmic reticulum protein 29 1 1
MIRT023300 MEP1A meprin A subunit alpha 1 1
MIRT023301 SPTLC1 serine palmitoyltransferase long chain base subunit 1 1 1
MIRT023302 GTF2H2 general transcription factor IIH subunit 2 1 1
MIRT023303 C14orf39 chromosome 14 open reading frame 39 1 1
MIRT023304 UBE2K ubiquitin conjugating enzyme E2 K 1 1
MIRT023305 PPP1R9B protein phosphatase 1 regulatory subunit 9B 1 1
MIRT023306 PSMD10 proteasome 26S subunit, non-ATPase 10 1 1
MIRT023307 CALD1 caldesmon 1 1 1
MIRT023308 TTYH3 tweety family member 3 1 1
MIRT023309 NMNAT2 nicotinamide nucleotide adenylyltransferase 2 1 1
MIRT023310 SCN4B sodium voltage-gated channel beta subunit 4 1 1
MIRT023311 C1orf122 chromosome 1 open reading frame 122 1 1
MIRT023312 PAK1 p21 (RAC1) activated kinase 1 1 1
MIRT023313 DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 1 1
MIRT023314 DMXL1 Dmx like 1 1 1
MIRT023315 ZNF160 zinc finger protein 160 1 1
MIRT023316 CSRP1 cysteine and glycine rich protein 1 1 1
MIRT023317 PHKA1 phosphorylase kinase regulatory subunit alpha 1 1 1
MIRT023318 RBBP5 RB binding protein 5, histone lysine methyltransferase complex subunit 1 1
MIRT023319 ANKRD13C ankyrin repeat domain 13C 1 1
MIRT023320 SUCLA2 succinate-CoA ligase ADP-forming beta subunit 1 1
MIRT023321 PEA15 phosphoprotein enriched in astrocytes 15 1 1
MIRT023322 MTPN myotrophin 1 1
MIRT023323 YKT6 YKT6 v-SNARE homolog 1 1
MIRT023324 MOB3B MOB kinase activator 3B 1 1
MIRT023325 FAM118A family with sequence similarity 118 member A 1 1
MIRT023326 ZNF264 zinc finger protein 264 1 1
MIRT023327 HECTD3 HECT domain E3 ubiquitin protein ligase 3 1 1
MIRT023328 BATF2 basic leucine zipper ATF-like transcription factor 2 1 1
MIRT023329 PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha 1 1
MIRT023330 MAPRE1 microtubule associated protein RP/EB family member 1 1 1
MIRT023331 TBC1D22B TBC1 domain family member 22B 1 1
MIRT023332 SLC9A1 solute carrier family 9 member A1 2 2
MIRT023333 NPEPPS aminopeptidase puromycin sensitive 1 1
MIRT023334 BCL2L1 BCL2 like 1 2 1
MIRT023335 OSMR oncostatin M receptor 1 1
MIRT023336 CALU calumenin 1 1
MIRT023337 BRI3BP BRI3 binding protein 1 1
MIRT023338 PSPH phosphoserine phosphatase 1 1
MIRT023339 APMAP adipocyte plasma membrane associated protein 1 1
MIRT023340 WASF1 WAS protein family member 1 1 1
MIRT023341 LCA5 LCA5, lebercilin 1 1
MIRT023342 NODAL nodal growth differentiation factor 1 1
MIRT023343 CASP7 caspase 7 1 1
MIRT023344 CPA3 carboxypeptidase A3 1 1
MIRT023345 PALM paralemmin 1 1
MIRT023346 TCP11 t-complex 11 1 1
MIRT023347 NALCN sodium leak channel, non-selective 1 1
MIRT023348 PLAGL2 PLAG1 like zinc finger 2 1 1
MIRT023349 IDS iduronate 2-sulfatase 2 2
MIRT023350 PARP11 poly(ADP-ribose) polymerase family member 11 1 1
MIRT023351 MAZ MYC associated zinc finger protein 1 1
MIRT023352 CPNE4 copine 4 1 1
MIRT023353 FAM19A3 family with sequence similarity 19 member A3, C-C motif chemokine like 1 1
MIRT023354 KRT14 keratin 14 1 1
MIRT023355 DYNC1H1 dynein cytoplasmic 1 heavy chain 1 1 1
MIRT023356 GNL3L G protein nucleolar 3 like 1 1
MIRT023357 HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1 1
MIRT023358 EYA4 EYA transcriptional coactivator and phosphatase 4 1 1
MIRT023359 GNPDA2 glucosamine-6-phosphate deaminase 2 1 1
MIRT023360 BRCA2 BRCA2, DNA repair associated 1 1
MIRT023361 ZSCAN4 zinc finger and SCAN domain containing 4 1 1
MIRT023362 HSPA5 heat shock protein family A (Hsp70) member 5 1 1
MIRT023363 SERAC1 serine active site containing 1 1 1
MIRT023364 SLC15A2 solute carrier family 15 member 2 1 1
MIRT023365 RABIF RAB interacting factor 1 1
MIRT023366 ART3 ADP-ribosyltransferase 3 1 1
MIRT023367 EP400 E1A binding protein p400 1 1
MIRT023368 MT4 metallothionein 4 1 1
MIRT023369 TRAM2 translocation associated membrane protein 2 1 1
MIRT023370 PHPT1 phosphohistidine phosphatase 1 1 1
MIRT023371 KIAA0101 PCNA clamp associated factor 1 1
MIRT023372 VHL von Hippel-Lindau tumor suppressor 1 1
MIRT023373 IFNA1 interferon alpha 1 1 1
MIRT023374 FSTL3 follistatin like 3 1 1
MIRT023375 PHF14 PHD finger protein 14 1 1
MIRT023376 ZCCHC2 zinc finger CCHC-type containing 2 1 1
MIRT023377 GSTM3 glutathione S-transferase mu 3 1 1
MIRT023378 DCTN5 dynactin subunit 5 1 1
MIRT023379 CHST3 carbohydrate sulfotransferase 3 1 1
MIRT023380 HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 1 1
MIRT023381 ADO 2-aminoethanethiol dioxygenase 1 1
MIRT023382 POMZP3 POM121 and ZP3 fusion 1 1
MIRT023383 CHST12 carbohydrate sulfotransferase 12 1 1
MIRT023384 ARSB arylsulfatase B 1 1
MIRT023385 ATP7A ATPase copper transporting alpha 1 1
MIRT023386 PMP22 peripheral myelin protein 22 1 1
MIRT023387 TGFBRAP1 transforming growth factor beta receptor associated protein 1 1 1
MIRT023388 ORC2 origin recognition complex subunit 2 1 1
MIRT023389 CREB1 cAMP responsive element binding protein 1 1 1
MIRT023390 CD83 CD83 molecule 1 1
MIRT023391 TOB2 transducer of ERBB2, 2 2 3
MIRT023392 LRP11 LDL receptor related protein 11 1 1
MIRT023393 MPV17 MPV17, mitochondrial inner membrane protein 1 1
MIRT023394 TRIM29 tripartite motif containing 29 1 1
MIRT023395 OSBP2 oxysterol binding protein 2 1 1
MIRT023397 FOXK2 forkhead box K2 2 2
MIRT023399 ST6GALNAC4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 1 1
MIRT023400 SMURF2 SMAD specific E3 ubiquitin protein ligase 2 1 1
MIRT023401 LMNB2 lamin B2 2 3
MIRT023402 BAX BCL2 associated X, apoptosis regulator 2 2
MIRT054362 Cux1 cut-like homeobox 1 1 1
MIRT074336 TNRC6A trinucleotide repeat containing 6A 1 1
MIRT109185 VMA21 VMA21, vacuolar ATPase assembly factor 1 2
MIRT324745 ACER2 alkaline ceramidase 2 1 1
MIRT325564 HIATL1 major facilitator superfamily domain containing 14B 1 2
MIRT438206 TGFB1 transforming growth factor beta 1 1 1
MIRT449879 CYP3A5 cytochrome P450 family 3 subfamily A member 5 2 1
MIRT451716 OLR1 oxidized low density lipoprotein receptor 1 1 1
MIRT453274 EFTUD2 elongation factor Tu GTP binding domain containing 2 1 1
MIRT454113 MRPL52 mitochondrial ribosomal protein L52 1 1
MIRT454232 OSBPL10 oxysterol binding protein like 10 1 7
MIRT454344 CDKL1 cyclin dependent kinase like 1 1 1
MIRT455826 ZSWIM1 zinc finger SWIM-type containing 1 1 1
MIRT459903 PIGO phosphatidylinositol glycan anchor biosynthesis class O 1 6
MIRT461654 G6PC glucose-6-phosphatase catalytic subunit 1 1
MIRT461934 TNFSF14 TNF superfamily member 14 1 1
MIRT463834 WSB1 WD repeat and SOCS box containing 1 1 1
MIRT468615 SUMO1 small ubiquitin-like modifier 1 1 1
MIRT469456 REL REL proto-oncogene, NF-kB subunit 1 3
MIRT469637 RAD21 RAD21 cohesin complex component 1 3
MIRT473432 MDM4 MDM4, p53 regulator 1 1
MIRT473872 MAFK MAF bZIP transcription factor K 1 3
MIRT476861 FHL2 four and a half LIM domains 2 1 2
MIRT476893 FBXO21 F-box protein 21 1 1
MIRT479880 CCDC43 coiled-coil domain containing 43 1 1
MIRT488848 UBTF upstream binding transcription factor, RNA polymerase I 1 1
MIRT491164 LRP3 LDL receptor related protein 3 1 1
MIRT497662 PRMT3 protein arginine methyltransferase 3 1 1
MIRT499314 ZNF485 zinc finger protein 485 1 5
MIRT499759 CIRH1A UTP4, small subunit processome component 1 5
MIRT500014 ABCF2 ATP binding cassette subfamily F member 2 1 4
MIRT501090 SLC7A5 solute carrier family 7 member 5 1 2
MIRT509646 ZNF354B zinc finger protein 354B 1 5
MIRT509945 TOMM70A translocase of outer mitochondrial membrane 70 1 3
MIRT510320 SLC2A3 solute carrier family 2 member 3 1 2
MIRT515505 GTF2F1 general transcription factor IIF subunit 1 1 1
MIRT516410 COPA coatomer protein complex subunit alpha 1 1
MIRT517861 NCAPD2 non-SMC condensin I complex subunit D2 1 2
MIRT522558 MCAM melanoma cell adhesion molecule 1 2
MIRT523525 GLUL glutamate-ammonia ligase 1 1
MIRT523764 FBXO27 F-box protein 27 1 2
MIRT524517 CDK19 cyclin dependent kinase 19 1 1
MIRT524753 BIRC5 baculoviral IAP repeat containing 5 1 3
MIRT529366 YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta 1 2
MIRT531189 SIGLEC12 sialic acid binding Ig like lectin 12 (gene/pseudogene) 1 1
MIRT531639 C19orf52 translocase of inner mitochondrial membrane 29 1 2
MIRT531913 SLC4A1 solute carrier family 4 member 1 (Diego blood group) 1 1
MIRT532678 PATZ1 POZ/BTB and AT hook containing zinc finger 1 1 1
MIRT533115 YIPF4 Yip1 domain family member 4 1 2
MIRT534740 RBM47 RNA binding motif protein 47 1 1
MIRT535471 PARVB parvin beta 1 2
MIRT536742 HSPA4L heat shock protein family A (Hsp70) member 4 like 1 1
MIRT537237 GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 1 1
MIRT539523 ABCF1 ATP binding cassette subfamily F member 1 1 2
MIRT540438 RBM43 RNA binding motif protein 43 1 1
MIRT542982 ERC1 ELKS/RAB6-interacting/CAST family member 1 1 1
MIRT544674 AP1S1 adaptor related protein complex 1 sigma 1 subunit 1 1
MIRT549514 HDDC2 HD domain containing 2 1 1
MIRT549663 ORC6 origin recognition complex subunit 6 1 2
MIRT555420 PPIC peptidylprolyl isomerase C 1 1
MIRT564701 ZNF322P1 zinc finger protein 322 pseudogene 1 1 1
MIRT570046 PKNOX1 PBX/knotted 1 homeobox 1 1 1
MIRT570257 PRSS16 protease, serine 16 1 1
MIRT571143 HM13 histocompatibility minor 13 1 1
MIRT575202 Entpd4 ectonucleoside triphosphate diphosphohydrolase 4 1 1
MIRT575282 Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 1 1
MIRT575302 Osbpl10 oxysterol binding protein-like 10 1 1
MIRT575323 Fbxo6 F-box protein 6 1 1
MIRT575377 Ang angiogenin, ribonuclease, RNase A family, 5 1 1
MIRT575614 Zswim1 zinc finger SWIM-type containing 1 1 1
MIRT575671 Map1b microtubule-associated protein 1B 1 1
MIRT607065 POM121L7 POM121 transmembrane nucleoporin like 7 pseudogene 1 1
MIRT607490 HEBP2 heme binding protein 2 1 1
MIRT607522 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 1 1
MIRT607655 BTN3A2 butyrophilin subfamily 3 member A2 1 1
MIRT607795 RHBDL2 rhomboid like 2 1 1
MIRT607842 PHLDA3 pleckstrin homology like domain family A member 3 1 1
MIRT607927 ANG angiogenin 1 1
MIRT607966 SNX22 sorting nexin 22 1 1
MIRT608074 ZFP14 ZFP14 zinc finger protein 1 1
MIRT608141 SYAP1 synapse associated protein 1 1 1
MIRT612620 RABL3 RAB, member of RAS oncogene family like 3 1 1
MIRT617444 CCS copper chaperone for superoxide dismutase 1 1
MIRT617552 MTO1 mitochondrial tRNA translation optimization 1 1 1
MIRT618772 HLA-E major histocompatibility complex, class I, E 1 1
MIRT618926 MEAF6 MYST/Esa1 associated factor 6 1 1
MIRT619247 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 1 1
MIRT620091 YME1L1 YME1 like 1 ATPase 1 1
MIRT620483 XKR6 XK related 6 1 1
MIRT620570 WBSCR27 methyltransferase like 27 1 2
MIRT622977 ORAI2 ORAI calcium release-activated calcium modulator 2 1 1
MIRT623169 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 1 1
MIRT624165 DGKE diacylglycerol kinase epsilon 1 1
MIRT625268 AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 1 1
MIRT625396 AKR7L aldo-keto reductase family 7 like (gene/pseudogene) 1 1
MIRT625694 OPTN optineurin 1 1
MIRT626093 MKLN1 muskelin 1 1 1
MIRT626431 CHDH choline dehydrogenase 1 1
MIRT627013 FIG4 FIG4 phosphoinositide 5-phosphatase 1 1
MIRT627077 SF3A1 splicing factor 3a subunit 1 1 1
MIRT627140 HS3ST1 heparan sulfate-glucosamine 3-sulfotransferase 1 1 1
MIRT627347 TSHZ2 teashirt zinc finger homeobox 2 1 1
MIRT627420 THAP2 THAP domain containing 2 1 1
MIRT627441 TAS2R5 taste 2 receptor member 5 1 1
MIRT628078 KAT7 lysine acetyltransferase 7 1 2
MIRT628276 CYB5D1 cytochrome b5 domain containing 1 1 1
MIRT629094 F2RL1 F2R like trypsin receptor 1 1 1
MIRT629236 CINP cyclin dependent kinase 2 interacting protein 1 1
MIRT629286 UNC13A unc-13 homolog A 1 1
MIRT629407 ADM2 adrenomedullin 2 1 1
MIRT629584 RFC2 replication factor C subunit 2 1 1
MIRT629635 WDR31 WD repeat domain 31 1 1
MIRT629874 NOM1 nucleolar protein with MIF4G domain 1 1 1
MIRT629984 NARS asparaginyl-tRNA synthetase 1 1
MIRT630043 TERF2 telomeric repeat binding factor 2 1 1
MIRT630061 NIP7 NIP7, nucleolar pre-rRNA processing protein 1 1
MIRT630127 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 1
MIRT630155 ZBTB8A zinc finger and BTB domain containing 8A 1 1
MIRT630252 SMTNL2 smoothelin like 2 1 1
MIRT630278 PSMB5 proteasome subunit beta 5 1 1
MIRT630347 NKAP NFKB activating protein 1 1
MIRT630497 CYP20A1 cytochrome P450 family 20 subfamily A member 1 1 1
MIRT631264 CENPM centromere protein M 1 1
MIRT631403 IL2RA interleukin 2 receptor subunit alpha 1 1
MIRT632470 RPS15A ribosomal protein S15a 1 1
MIRT632596 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 1 1
MIRT632994 DUSP18 dual specificity phosphatase 18 1 1
MIRT633082 CXorf21 chromosome X open reading frame 21 1 1
MIRT633239 ZNF573 zinc finger protein 573 1 1
MIRT633286 SLC1A5 solute carrier family 1 member 5 1 1
MIRT633536 PGBD5 piggyBac transposable element derived 5 1 1
MIRT634338 SGOL1 shugoshin 1 1 1
MIRT634600 KIAA1919 major facilitator superfamily domain containing 4B 1 1
MIRT635050 MYH11 myosin heavy chain 11 1 1
MIRT635236 QPRT quinolinate phosphoribosyltransferase 1 1
MIRT635322 BMS1 BMS1, ribosome biogenesis factor 1 1
MIRT636268 RNF157 ring finger protein 157 1 1
MIRT636450 LRCH3 leucine rich repeats and calponin homology domain containing 3 1 1
MIRT636516 FMN1 formin 1 1 1
MIRT636755 SLC16A5 solute carrier family 16 member 5 1 1
MIRT637134 BAMBI BMP and activin membrane bound inhibitor 1 1
MIRT637188 ROMO1 reactive oxygen species modulator 1 1 1
MIRT637287 IBA57 IBA57 homolog, iron-sulfur cluster assembly 1 1
MIRT637532 RGS9BP regulator of G protein signaling 9 binding protein 1 1
MIRT637693 CEP89 centrosomal protein 89 1 1
MIRT637788 OLA1 Obg like ATPase 1 1 1
MIRT637925 LILRA2 leukocyte immunoglobulin like receptor A2 1 1
MIRT638449 PLXDC2 plexin domain containing 2 1 1
MIRT640871 ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 1 1
MIRT642643 PTGR2 prostaglandin reductase 2 1 1
MIRT643082 PTPLAD2 3-hydroxyacyl-CoA dehydratase 4 1 1
MIRT643123 FAM71F2 family with sequence similarity 71 member F2 1 1
MIRT644236 SLC35E3 solute carrier family 35 member E3 1 1
MIRT644665 TMCO1 transmembrane and coiled-coil domains 1 1 1
MIRT645092 SLC35E2B solute carrier family 35 member E2B 1 1
MIRT645993 ACP6 acid phosphatase 6, lysophosphatidic 1 1
MIRT646508 FAM217B family with sequence similarity 217 member B 1 1
MIRT647013 ADCY2 adenylate cyclase 2 1 1
MIRT647095 SEC23B Sec23 homolog B, coat complex II component 1 1
MIRT647714 NFX1 nuclear transcription factor, X-box binding 1 1 2
MIRT648040 FADS6 fatty acid desaturase 6 1 1
MIRT648510 PIGG phosphatidylinositol glycan anchor biosynthesis class G 1 1
MIRT648865 ABCA6 ATP binding cassette subfamily A member 6 1 1
MIRT649182 DNPEP aspartyl aminopeptidase 1 1
MIRT649660 TEP1 telomerase associated protein 1 1 1
MIRT651465 XIAP X-linked inhibitor of apoptosis 1 1
MIRT652398 TMEM40 transmembrane protein 40 1 1
MIRT653691 SLC25A33 solute carrier family 25 member 33 1 1
MIRT654122 RPS6KA5 ribosomal protein S6 kinase A5 1 1
MIRT654577 PXMP4 peroxisomal membrane protein 4 1 1
MIRT656470 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 1 1
MIRT658905 DPY19L4 dpy-19 like 4 1 1
MIRT660878 ADRBK2 G protein-coupled receptor kinase 3 1 2
MIRT661101 SPIB Spi-B transcription factor 1 1
MIRT661238 ARL17B ADP ribosylation factor like GTPase 17B 1 1
MIRT661291 LIN52 lin-52 DREAM MuvB core complex component 1 1
MIRT662235 PGBD4 piggyBac transposable element derived 4 1 1
MIRT662544 MTAP methylthioadenosine phosphorylase 1 1
MIRT662736 LRRC3C leucine rich repeat containing 3C 1 1
MIRT662844 OMD osteomodulin 1 1
MIRT662907 MED18 mediator complex subunit 18 1 1
MIRT662956 JPH2 junctophilin 2 1 1
MIRT663340 ZNF74 zinc finger protein 74 1 1
MIRT663496 IYD iodotyrosine deiodinase 1 1
MIRT663523 MASTL microtubule associated serine/threonine kinase like 1 1
MIRT663542 CCR6 C-C motif chemokine receptor 6 1 1
MIRT663903 MRI1 methylthioribose-1-phosphate isomerase 1 1 1
MIRT663973 ZNF786 zinc finger protein 786 1 1
MIRT664350 C16orf45 chromosome 16 open reading frame 45 1 1
MIRT664417 TIGD6 tigger transposable element derived 6 1 1
MIRT664468 ZYG11B zyg-11 family member B, cell cycle regulator 1 1
MIRT664957 PTCD3 pentatricopeptide repeat domain 3 1 1
MIRT664970 TDRD1 tudor domain containing 1 1 1
MIRT665199 ESF1 ESF1 nucleolar pre-rRNA processing protein homolog 1 1
MIRT665359 XKR4 XK related 4 1 1
MIRT665454 WDR17 WD repeat domain 17 1 1
MIRT665486 VPS53 VPS53, GARP complex subunit 1 1
MIRT666078 SSTR2 somatostatin receptor 2 1 1
MIRT666258 SLC31A1 solute carrier family 31 member 1 1 1
MIRT666324 SLC16A10 solute carrier family 16 member 10 1 1
MIRT666486 SBNO1 strawberry notch homolog 1 1 1
MIRT666696 RBM23 RNA binding motif protein 23 1 1
MIRT666712 RBL1 RB transcriptional corepressor like 1 1 1
MIRT666762 RAB10 RAB10, member RAS oncogene family 1 1
MIRT666931 PNRC1 proline rich nuclear receptor coactivator 1 1 1
MIRT667226 NFE2L1 nuclear factor, erythroid 2 like 1 1 1
MIRT667359 MPLKIP M-phase specific PLK1 interacting protein 1 1
MIRT667474 MAPK1 mitogen-activated protein kinase 1 1 1
MIRT667558 LRAT lecithin retinol acyltransferase 1 1
MIRT667748 KDELR1 KDEL endoplasmic reticulum protein retention receptor 1 1 1
MIRT668088 GMEB1 glucocorticoid modulatory element binding protein 1 1 1
MIRT668119 GK5 glycerol kinase 5 (putative) 1 1
MIRT668166 GDE1 glycerophosphodiester phosphodiesterase 1 1 1
MIRT668346 STXBP2 syntaxin binding protein 2 1 1
MIRT668509 ESYT2 extended synaptotagmin 2 1 1
MIRT669291 C17orf85 nuclear cap binding subunit 3 1 1
MIRT669547 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 1 1
MIRT669778 CNDP1 carnosine dipeptidase 1 1 1
MIRT669858 BROX BRO1 domain and CAAX motif containing 1 2
MIRT670017 TECPR1 tectonin beta-propeller repeat containing 1 1 1
MIRT670177 CCDC142 coiled-coil domain containing 142 1 1
MIRT671107 ZNF841 zinc finger protein 841 1 1
MIRT671351 SMG1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 1 1
MIRT671476 FLYWCH2 FLYWCH family member 2 1 1
MIRT671492 SLC38A9 solute carrier family 38 member 9 1 1
MIRT671554 LIMS1 LIM zinc finger domain containing 1 1 1
MIRT671925 PLEKHS1 pleckstrin homology domain containing S1 1 2
MIRT672196 F2 coagulation factor II, thrombin 1 1
MIRT672217 DCAF7 DDB1 and CUL4 associated factor 7 1 1
MIRT672252 SIK2 salt inducible kinase 2 1 1
MIRT672290 GP2 glycoprotein 2 1 1
MIRT672430 POLR2D RNA polymerase II subunit D 1 1
MIRT672597 NKPD1 NTPase KAP family P-loop domain containing 1 1 1
MIRT672901 KRBA2 KRAB-A domain containing 2 1 1
MIRT672958 ZNF655 zinc finger protein 655 1 1
MIRT673096 SYNPO2L synaptopodin 2 like 1 1
MIRT673171 TMEM56 transmembrane protein 56 1 1
MIRT673251 INO80 INO80 complex subunit 1 1
MIRT673296 RNF19B ring finger protein 19B 1 1
MIRT673574 KDELC2 KDEL motif containing 2 1 1
MIRT673586 KIF1C kinesin family member 1C 1 1
MIRT673737 TCF23 transcription factor 23 1 1
MIRT673767 MRPL17 mitochondrial ribosomal protein L17 1 1
MIRT674215 FAM120AOS family with sequence similarity 120A opposite strand 1 1
MIRT674283 NAGK N-acetylglucosamine kinase 1 1
MIRT674338 KCMF1 potassium channel modulatory factor 1 1 1
MIRT674517 PRR23A proline rich 23A 1 1
MIRT675100 SNTB2 syntrophin beta 2 1 1
MIRT675144 MOGAT1 monoacylglycerol O-acyltransferase 1 1 2
MIRT675223 CLK4 CDC like kinase 4 1 1
MIRT675263 ZNF431 zinc finger protein 431 1 1
MIRT675577 WWC1 WW and C2 domain containing 1 1 1
MIRT676025 C9orf69 transmembrane protein 250 1 1
MIRT676430 PLEKHM3 pleckstrin homology domain containing M3 1 1
MIRT676560 VSIG1 V-set and immunoglobulin domain containing 1 1 1
MIRT676596 ARIH2OS ariadne RBR E3 ubiquitin protein ligase 2 opposite strand 1 1
MIRT678576 TMEM168 transmembrane protein 168 1 1
MIRT678756 ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 1 1
MIRT680344 ZNF281 zinc finger protein 281 1 1
MIRT680467 C3 complement C3 1 1
MIRT682826 FLG2 filaggrin family member 2 1 1
MIRT682881 SAR1A secretion associated Ras related GTPase 1A 1 1
MIRT684404 TMEM180 major facilitator superfamily domain containing 13A 1 1
MIRT685275 KIAA1143 KIAA1143 1 1
MIRT686061 KCNA7 potassium voltage-gated channel subfamily A member 7 1 1
MIRT687526 NASP nuclear autoantigenic sperm protein 1 1
MIRT691760 BCL2L15 BCL2 like 15 1 1
MIRT693890 C3orf62 chromosome 3 open reading frame 62 1 1
MIRT699342 SLC35E1 solute carrier family 35 member E1 1 1
MIRT699909 RUNDC1 RUN domain containing 1 1 1
MIRT700536 PTPDC1 protein tyrosine phosphatase domain containing 1 1 1
MIRT701807 MRPS25 mitochondrial ribosomal protein S25 1 1
MIRT702174 LYRM4 LYR motif containing 4 1 1
MIRT706205 ACOT9 acyl-CoA thioesterase 9 1 1
MIRT706659 RNF216 ring finger protein 216 1 1
MIRT706682 COL13A1 collagen type XIII alpha 1 chain 1 1
MIRT706705 GPR155 G protein-coupled receptor 155 1 1
MIRT706777 ANKRD36 ankyrin repeat domain 36 1 1
MIRT706844 DNAJB13 DnaJ heat shock protein family (Hsp40) member B13 1 1
MIRT706863 MAFF MAF bZIP transcription factor F 1 1
MIRT706896 ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 1 1
MIRT706916 THAP6 THAP domain containing 6 1 1
MIRT706962 FANCC Fanconi anemia complementation group C 1 1
MIRT706980 XPO5 exportin 5 1 1
MIRT707015 RRP36 ribosomal RNA processing 36 1 1
MIRT707032 ACTR5 ARP5 actin related protein 5 homolog 1 1
MIRT707072 MED29 mediator complex subunit 29 1 1
MIRT709368 SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 1 1
MIRT720092 SPTLC3 serine palmitoyltransferase long chain base subunit 3 1 1
MIRT721330 IFNAR2 interferon alpha and beta receptor subunit 2 1 1
MIRT724198 MED7 mediator complex subunit 7 1 1
MIRT725403 KIF6 kinesin family member 6 1 1
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