miRTarBase - #MIRT626431 -
pre-miRNA Information
pre-miRNA hsa-mir-122   
Genomic Coordinates chr18: 58451074 - 58451158
Synonyms MIR122A, MIRN122, MIRN122A, hsa-mir-122, miRNA122, miRNA122A, MIR122
Description Homo sapiens miR-122 stem-loop
Comment The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-122-5p
Sequence 15| UGGAGUGUGACAAUGGUGUUUG |36
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 4 18 + 58451091 29233923 MiREDiBase
C-to-U 11 18 + 58451098 28550310 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1258166649 1 dbSNP
rs1426570658 6 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles

Circulating MicroRNA Expression Profiling
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol CHDH   
Synonyms -
Description choline dehydrogenase
Transcript NM_018397   
Expression
Putative miRNA Targets on CHDH
3'UTR of CHDH
(miRNA target sites are highlighted)
>CHDH|NM_018397|3'UTR
   1 GACAGTTGCTGCTGGAGGATGACCAGGGAAGCCCCCTGATAAGCCAAGAGGGCCAGCACAGCCCTTGCTCCCAGGCTCCT
  81 GCCTGAAACTATCTAGCACACTAGGACCCAGGTGGTACCCTACTCAGTGGCTGAGAATTGGATAAAGTCTTGGGAAATGA
 161 GACAAGTACTGGGCAGTGAATCCAGCTCCTTTTCCCCAGCCTTTCCCTGTGGGCCATTTGGGGAAGGCCAGCATTCAGCC
 241 TGAGATGTTCCTCCCTGCCTCCTGGAGGGACAGAAGGGGAGGATGGTTAACTCCTGCCGCATCCTTTTTCTTGTGTTCAC
 321 GTGGCATTCTCTAACCCAGGGCAGTGGTTCCTTCCCAGGCCATGCACAGAGGCTGGGTGCCTGCCAGACCCACGGAGGGT
 401 TCGCGAAGGAAGGGGCATCCTCCTTCTTGAGCTGCAAGCTTTAGCTGAGGCAGTAAGTCACACAGTAGTTAGTTCAGCCT
 481 GGGCTGGCACATAAGTCCCCAGTGTCCCTGTTGAGAGGGGAAAGTTGCCTGCTGGTTGAAAAACTGGCTTTTCCTTTCTC
 561 GCTGCCTAATTTCACTCTCAGAGTGAGGCAGGTAACTGGGGCTCCACTGGGTCACTCTGAGAGGGTTGTGGCTCTGGTTC
 641 TTATTAAACCAGGGCCAGGTGCAGGGCTCACACCTGTAATCCCAGCACTTTGGGAAGGTCACTTGAGCTCAGGAGTTCAA
 721 GACCAGCCTGGGCAACATAGTGAGACCTTGTCTCTGGAAAACAATTAGCTGGGCATGGTGGTACACACCTGTAGTCCCAG
 801 CTACTTGGGAGGCTGAGGCGGGAGGATGGCTTTAGCCCAGGAGGTTGAGGCTCCTGTGAACCCTGATGGCACCACTGCAC
 881 TCCAGCCTGGGTGACAGGGTGAGACCCTGTCTCAAAAAAAAAAAAAAAAAAAAAAACCTGAGATTTTTTTGGACCTTATT
 961 CAAGGGGAGAGGAGTCTGGAGGGAATGCCGCTTGGCTTCACTACCAAAGGTTTTATGACTTAGCATTTTAAAAGGTTTTC
1041 CTTTTACCAAGAAATGCAGAAACCAAGAGCAAACCCCACGTACCAGATCACTGATTCCTACTGAAGCAGCTAGCCCGAGA
1121 AAGGACTCTCTCATACTGGTCTTGGGAAATGACTTGGCAGCCTGAGCCATCCCAGCAGTGGACAAGGATGGTTAATTCTT
1201 ATTCTGTAGACGTCCACAGGAACAGACTAGGATGGAAAACACAGTTAAGCACAGCCATGCACCCTGTGGCTGTAGAAATG
1281 CCCCTGTGTGAAAGAAAAATAAATTCAAGACTGGAGTTTTGGAGGAAAAAAAATACAAGTAGCATTTACAACAGCTCTTT
1361 GCTCTTTAAATTTCTTACCATTCAATAAAGTGATCCAGTCACTCACATTTGAACTGAGATGCCTTCTCCAGACTGTTCTG
1441 ACAAGGTAATGAAAATAAAATGCACTTGGATTTTTCCAGAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions (Predicted by miRanda)
IDDuplex structurePositionScoreMFE
1
miRNA  3' guUUGUGGUAACAGUGUGAGGu 5'
            ::||||| |   :|||||| 
Target 5' atGGCACCACT---GCACTCCa 3'
866 - 884 141.00 -18.40
2
miRNA  3' guUUGUGGUAACAGUGUGAGGu 5'
            ::||: :| || |||| || 
Target 5' tgGGCATGGTGGT-ACACACCt 3'
770 - 790 123.00 -11.60
3
miRNA  3' guUUGUGGUA-ACAGUGUGAggu 5'
            :| ||:|| |  ||||||   
Target 5' ctGAAACTATCTAGCACACTagg 3'
83 - 105 120.00 -9.82
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30101518 14 COSMIC
COSN19728387 17 COSMIC
COSN30100133 18 COSMIC
COSN30100151 21 COSMIC
COSN31574581 61 COSMIC
COSN31512375 85 COSMIC
COSN9721641 119 COSMIC
COSN30213323 188 COSMIC
COSN229055 299 COSMIC
COSN7763157 302 COSMIC
COSN16404822 303 COSMIC
COSN24371969 393 COSMIC
COSN22574638 967 COSMIC
COSN17037449 1194 COSMIC
COSN9554088 1651 COSMIC
COSN15162570 1703 COSMIC
COSN17215777 2496 COSMIC
COSN1952779 3177 COSMIC
COSN7763156 3187 COSMIC
COSN7763155 3364 COSMIC
COSN23870440 3673 COSMIC
COSN9721639 3729 COSMIC
COSN6770213 3904 COSMIC
COSN1952777 3987 COSMIC
COSN1952775 4311 COSMIC
COSN30271530 4363 COSMIC
COSN27319649 4439 COSMIC
COSN6770212 4456 COSMIC
COSN28552586 4645 COSMIC
COSN18891216 4742 COSMIC
COSN8312208 4880 COSMIC
COSN29111323 4946 COSMIC
COSN21657929 5119 COSMIC
COSN9721638 5221 COSMIC
COSN31962071 5328 COSMIC
COSN23690517 5431 COSMIC
COSN9554087 5439 COSMIC
rs145601829 299 GWAS
rs11130381 1799 GWAS
rs14165 4396 GWAS
rs893363 4742 GWAS
rs877483 5063 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs769815478 1 dbSNP
rs1055835048 2 dbSNP
rs759630876 3 dbSNP
rs111450925 4 dbSNP
rs1221599129 12 dbSNP
rs1369725714 23 dbSNP
rs1294049550 26 dbSNP
rs557223892 32 dbSNP
rs1342950842 37 dbSNP
rs201355737 38 dbSNP
rs746797465 45 dbSNP
rs568422934 47 dbSNP
rs888547015 51 dbSNP
rs1054224326 53 dbSNP
rs1047190029 55 dbSNP
rs764063975 55 dbSNP
rs930144488 59 dbSNP
rs1427290228 70 dbSNP
rs147713779 78 dbSNP
rs759548864 79 dbSNP
rs535087835 82 dbSNP
rs942961896 89 dbSNP
rs1340328235 91 dbSNP
rs1436689698 94 dbSNP
rs1276260285 100 dbSNP
rs1211073075 102 dbSNP
rs912808207 108 dbSNP
rs566179071 122 dbSNP
rs552358378 123 dbSNP
rs1355822329 127 dbSNP
rs1222658431 129 dbSNP
rs930155735 135 dbSNP
rs910857863 136 dbSNP
rs989122741 140 dbSNP
rs529254855 143 dbSNP
rs963147097 147 dbSNP
rs1248743504 148 dbSNP
rs1365955106 153 dbSNP
rs927315231 159 dbSNP
rs1381439993 163 dbSNP
rs567394748 167 dbSNP
rs1388372439 169 dbSNP
rs1360222835 171 dbSNP
rs1406323410 174 dbSNP
rs1325106010 182 dbSNP
rs977900259 183 dbSNP
rs1458156899 184 dbSNP
rs970966596 185 dbSNP
rs1351263006 186 dbSNP
rs1166266655 191 dbSNP
rs1024839952 192 dbSNP
rs1012158581 194 dbSNP
rs1237801864 199 dbSNP
rs1024658225 201 dbSNP
rs1390222906 236 dbSNP
rs1010050179 241 dbSNP
rs1191106698 245 dbSNP
rs762489699 246 dbSNP
rs955839313 247 dbSNP
rs1213338765 258 dbSNP
rs1238814770 259 dbSNP
rs1441638695 264 dbSNP
rs563519708 269 dbSNP
rs1267181834 279 dbSNP
rs181591871 284 dbSNP
rs1339961554 298 dbSNP
rs145601829 299 dbSNP
rs17053530 301 dbSNP
rs1272777052 304 dbSNP
rs1165409541 308 dbSNP
rs1047583222 313 dbSNP
rs1388088692 313 dbSNP
rs1460553769 314 dbSNP
rs1204647229 318 dbSNP
rs540693420 320 dbSNP
rs1038657673 321 dbSNP
rs1230599012 322 dbSNP
rs1246676895 324 dbSNP
rs1282172894 326 dbSNP
rs1355405840 337 dbSNP
rs901336149 341 dbSNP
rs1329272911 354 dbSNP
rs140389543 360 dbSNP
rs1459139890 363 dbSNP
rs571761850 365 dbSNP
rs911475226 366 dbSNP
rs1443535817 370 dbSNP
rs564649668 372 dbSNP
rs776799178 380 dbSNP
rs1190256940 382 dbSNP
rs1367028969 385 dbSNP
rs1475090115 386 dbSNP
rs930248970 387 dbSNP
rs897314640 389 dbSNP
rs1463588069 391 dbSNP
rs115082746 393 dbSNP
rs1402336166 394 dbSNP
rs936325005 398 dbSNP
rs923667403 403 dbSNP
rs552403370 404 dbSNP
rs550982256 405 dbSNP
rs941416916 409 dbSNP
rs1320329971 415 dbSNP
rs1216839463 425 dbSNP
rs927379984 427 dbSNP
rs768579589 428 dbSNP
rs1169931200 429 dbSNP
rs1202636109 434 dbSNP
rs1254777476 439 dbSNP
rs1485543466 441 dbSNP
rs978229335 441 dbSNP
rs1194910047 443 dbSNP
rs1264844515 447 dbSNP
rs1228643805 455 dbSNP
rs747556740 464 dbSNP
rs1377568426 466 dbSNP
rs1169335514 475 dbSNP
rs1177359866 483 dbSNP
rs917730564 489 dbSNP
rs990672186 491 dbSNP
rs1400355670 495 dbSNP
rs34378181 496 dbSNP
rs10626142 497 dbSNP
rs397731445 497 dbSNP
rs559280966 497 dbSNP
rs1250031795 498 dbSNP
rs1295136969 502 dbSNP
rs917279165 510 dbSNP
rs988714456 513 dbSNP
rs1254750468 525 dbSNP
rs1483498986 527 dbSNP
rs1016197114 531 dbSNP
rs1218027044 545 dbSNP
rs62250930 559 dbSNP
rs952803246 560 dbSNP
rs147577429 561 dbSNP
rs1025671562 566 dbSNP
rs1434383205 574 dbSNP
rs1196190393 575 dbSNP
rs1394367297 581 dbSNP
rs371719937 583 dbSNP
rs772624553 594 dbSNP
rs979004465 601 dbSNP
rs1358324273 623 dbSNP
rs964457752 628 dbSNP
rs189477345 630 dbSNP
rs1288499090 633 dbSNP
rs1368639872 640 dbSNP
rs1388562540 649 dbSNP
rs994630812 652 dbSNP
rs901283843 659 dbSNP
rs1019699639 661 dbSNP
rs1309403812 670 dbSNP
rs537737347 680 dbSNP
rs145132052 696 dbSNP
rs1215592948 702 dbSNP
rs1265640238 712 dbSNP
rs1443780268 715 dbSNP
rs554900274 718 dbSNP
rs1007018568 720 dbSNP
rs1207729954 722 dbSNP
rs534714175 738 dbSNP
rs1008539513 739 dbSNP
rs1180431171 740 dbSNP
rs1400820074 742 dbSNP
rs1173710073 745 dbSNP
rs889985543 746 dbSNP
rs1054442379 751 dbSNP
rs936964937 752 dbSNP
rs902165421 760 dbSNP
rs1324154801 768 dbSNP
rs1393745490 772 dbSNP
rs1158890221 773 dbSNP
rs994369693 786 dbSNP
rs746202900 788 dbSNP
rs1371869948 792 dbSNP
rs1042070972 804 dbSNP
rs1223545344 817 dbSNP
rs949094153 819 dbSNP
rs574269765 820 dbSNP
rs990619613 838 dbSNP
rs1272151162 839 dbSNP
rs937820031 839 dbSNP
rs1185631880 844 dbSNP
rs1200039295 847 dbSNP
rs560464699 850 dbSNP
rs148394206 851 dbSNP
rs1441948037 864 dbSNP
rs909085663 875 dbSNP
rs985098683 887 dbSNP
rs771610223 890 dbSNP
rs539162367 894 dbSNP
rs1415622663 898 dbSNP
rs1421840376 901 dbSNP
rs1201022751 905 dbSNP
rs1163046682 910 dbSNP
rs1462593039 911 dbSNP
rs1266094789 912 dbSNP
rs1172956339 913 dbSNP
rs1227569079 913 dbSNP
rs1352864737 914 dbSNP
rs1442046454 914 dbSNP
rs1303945149 915 dbSNP
rs1329536616 916 dbSNP
rs1280956002 917 dbSNP
rs1242119598 918 dbSNP
rs1318207643 919 dbSNP
rs1220127098 922 dbSNP
rs941540976 925 dbSNP
rs1334236974 926 dbSNP
rs1306427296 927 dbSNP
rs1210650037 929 dbSNP
rs905926334 929 dbSNP
rs1044857540 930 dbSNP
rs1320402570 931 dbSNP
rs950675890 932 dbSNP
rs1026041634 933 dbSNP
rs1391240398 934 dbSNP
rs972760809 936 dbSNP
rs1177417901 937 dbSNP
rs1202163646 937 dbSNP
rs1210115755 937 dbSNP
rs1268052274 937 dbSNP
rs1341549922 937 dbSNP
rs1360656638 937 dbSNP
rs1361461238 937 dbSNP
rs1409455064 937 dbSNP
rs1417391624 937 dbSNP
rs1429734788 937 dbSNP
rs1433216285 937 dbSNP
rs3079411 937 dbSNP
rs1472583872 938 dbSNP
rs1286399717 941 dbSNP
rs1369195930 941 dbSNP
rs1489153896 942 dbSNP
rs1195511240 944 dbSNP
rs11714712 949 dbSNP
rs1019647176 953 dbSNP
rs1006967696 955 dbSNP
rs144461528 961 dbSNP
rs1361498625 967 dbSNP
rs1032541604 972 dbSNP
rs1001497491 973 dbSNP
rs1286056000 974 dbSNP
rs1315773659 981 dbSNP
rs1207762767 982 dbSNP
rs777451247 986 dbSNP
rs529972455 989 dbSNP
rs4563403 990 dbSNP
rs779938438 994 dbSNP
rs925867134 998 dbSNP
rs1284357338 1001 dbSNP
rs374540464 1020 dbSNP
rs1233394204 1022 dbSNP
rs964920875 1022 dbSNP
rs1355574450 1023 dbSNP
rs1362339134 1023 dbSNP
rs547329133 1024 dbSNP
rs558250205 1030 dbSNP
rs1328612133 1033 dbSNP
rs1222620500 1046 dbSNP
rs184612853 1047 dbSNP
rs1254908885 1050 dbSNP
rs1321981611 1056 dbSNP
rs896187788 1058 dbSNP
rs993134117 1067 dbSNP
rs1165168354 1073 dbSNP
rs544684173 1079 dbSNP
rs149740306 1080 dbSNP
rs1005827146 1093 dbSNP
rs1187900462 1097 dbSNP
rs1439606504 1116 dbSNP
rs530025974 1117 dbSNP
rs1379078527 1134 dbSNP
rs563875458 1146 dbSNP
rs1449995097 1150 dbSNP
rs1356808628 1156 dbSNP
rs984659273 1161 dbSNP
rs766298003 1170 dbSNP
rs1450767169 1172 dbSNP
rs929175113 1178 dbSNP
rs1213201052 1186 dbSNP
rs1239285594 1187 dbSNP
rs919187338 1200 dbSNP
rs1180313877 1209 dbSNP
rs895907879 1211 dbSNP
rs543655401 1212 dbSNP
rs1415283366 1222 dbSNP
rs1460443895 1225 dbSNP
rs1339504194 1231 dbSNP
rs1401876154 1232 dbSNP
rs74840452 1233 dbSNP
rs762986986 1242 dbSNP
rs1229869951 1244 dbSNP
rs912584298 1246 dbSNP
rs1364704459 1249 dbSNP
rs1450027427 1254 dbSNP
rs1295328569 1256 dbSNP
rs985499288 1258 dbSNP
rs554953502 1260 dbSNP
rs925836320 1261 dbSNP
rs954143350 1266 dbSNP
rs1341578232 1269 dbSNP
rs139666092 1272 dbSNP
rs754647663 1287 dbSNP
rs1190572768 1305 dbSNP
rs1255888500 1314 dbSNP
rs4234642 1329 dbSNP
rs910367740 1334 dbSNP
rs987359893 1334 dbSNP
rs192184790 1342 dbSNP
rs1370089299 1354 dbSNP
rs1402887179 1356 dbSNP
rs554131598 1377 dbSNP
rs919021402 1380 dbSNP
rs187834555 1387 dbSNP
rs1354604317 1390 dbSNP
rs1169300932 1392 dbSNP
rs971683181 1393 dbSNP
rs1013884952 1398 dbSNP
rs1421588771 1400 dbSNP
rs1320849814 1406 dbSNP
rs1328266667 1408 dbSNP
rs896136850 1415 dbSNP
rs1251220173 1422 dbSNP
rs1346371926 1432 dbSNP
rs1213673540 1444 dbSNP
rs1170694563 1446 dbSNP
rs1015960480 1460 dbSNP
rs1485554587 1465 dbSNP
rs1216885620 1480 dbSNP
rs1054807511 1481 dbSNP
rs534651912 1484 dbSNP
rs1006210350 1487 dbSNP
rs1001929710 1494 dbSNP
rs1310141284 1495 dbSNP
rs1171697776 1501 dbSNP
rs1201197732 1508 dbSNP
rs374232544 1524 dbSNP
rs970375936 1524 dbSNP
rs1049336541 1525 dbSNP
rs929145060 1532 dbSNP
rs114149895 1538 dbSNP
rs567510100 1544 dbSNP
rs1237059751 1551 dbSNP
rs764248477 1559 dbSNP
rs895873796 1562 dbSNP
rs1040247557 1563 dbSNP
rs1053212131 1564 dbSNP
rs4687744 1565 dbSNP
rs1308696489 1567 dbSNP
rs1484667344 1579 dbSNP
rs1277156766 1583 dbSNP
rs1219121347 1591 dbSNP
rs1469419762 1592 dbSNP
rs4687588 1594 dbSNP
rs12485510 1595 dbSNP
rs1226867144 1596 dbSNP
rs879457748 1596 dbSNP
rs374057050 1599 dbSNP
rs1395306381 1600 dbSNP
rs1443273304 1612 dbSNP
rs1308808097 1614 dbSNP
rs1444492203 1615 dbSNP
rs925400665 1615 dbSNP
rs1357462107 1623 dbSNP
rs1332159987 1626 dbSNP
rs1369294631 1627 dbSNP
rs1413820118 1628 dbSNP
rs370435714 1629 dbSNP
rs1056296802 1631 dbSNP
rs1248074712 1632 dbSNP
rs12485507 1632 dbSNP
rs1158641914 1633 dbSNP
rs1443486900 1634 dbSNP
rs1458760899 1634 dbSNP
rs1293504791 1635 dbSNP
rs570896488 1635 dbSNP
rs1459086574 1636 dbSNP
rs796907732 1636 dbSNP
rs1021158895 1637 dbSNP
rs1186095207 1637 dbSNP
rs1013834008 1638 dbSNP
rs1461769426 1638 dbSNP
rs1181613676 1639 dbSNP
rs1357780962 1639 dbSNP
rs1471623300 1640 dbSNP
rs910471572 1640 dbSNP
rs1052005493 1641 dbSNP
rs531280770 1641 dbSNP
rs933175202 1642 dbSNP
rs1182399205 1643 dbSNP
rs1174828620 1644 dbSNP
rs1428390466 1644 dbSNP
rs1433316475 1644 dbSNP
rs59971943 1644 dbSNP
rs377576647 1645 dbSNP
rs796609986 1645 dbSNP
rs1286564340 1646 dbSNP
rs1305618888 1646 dbSNP
rs1345450697 1646 dbSNP
rs202031062 1646 dbSNP
rs547477516 1646 dbSNP
rs67976825 1646 dbSNP
rs766390909 1646 dbSNP
rs1218238344 1647 dbSNP
rs1447758440 1647 dbSNP
rs1491558973 1647 dbSNP
rs200856406 1648 dbSNP
rs960965591 1649 dbSNP
rs142483411 1650 dbSNP
rs71617780 1650 dbSNP
rs1397483130 1651 dbSNP
rs1443491555 1652 dbSNP
rs1265475569 1654 dbSNP
rs1226961329 1656 dbSNP
rs1452928628 1659 dbSNP
rs1033305928 1676 dbSNP
rs192124229 1680 dbSNP
rs1315795077 1681 dbSNP
rs1344084804 1682 dbSNP
rs370260005 1683 dbSNP
rs1327809028 1684 dbSNP
rs908868403 1684 dbSNP
rs887472376 1692 dbSNP
rs1048798477 1693 dbSNP
rs980466368 1698 dbSNP
rs970683228 1704 dbSNP
rs187538003 1707 dbSNP
rs1225612082 1712 dbSNP
rs1282493349 1716 dbSNP
rs1328550194 1720 dbSNP
rs1214441926 1724 dbSNP
rs1447290907 1727 dbSNP
rs897643243 1730 dbSNP
rs1198799353 1732 dbSNP
rs530225982 1737 dbSNP
rs1040198377 1738 dbSNP
rs1233744883 1742 dbSNP
rs753626295 1745 dbSNP
rs992971570 1745 dbSNP
rs1410827151 1755 dbSNP
rs1461476122 1756 dbSNP
rs1031873328 1759 dbSNP
rs1406748470 1768 dbSNP
rs910474520 1772 dbSNP
rs183350848 1780 dbSNP
rs139620672 1781 dbSNP
rs191567030 1781 dbSNP
rs1455472106 1784 dbSNP
rs762150203 1789 dbSNP
rs1439818582 1790 dbSNP
rs764171787 1792 dbSNP
rs11130381 1799 dbSNP
rs1234160162 1800 dbSNP
rs945483175 1803 dbSNP
rs1420485865 1804 dbSNP
rs187855848 1812 dbSNP
rs1180774442 1814 dbSNP
rs1444655302 1817 dbSNP
rs1439894982 1819 dbSNP
rs1180151879 1821 dbSNP
rs373210184 1833 dbSNP
rs1207346550 1836 dbSNP
rs576442085 1837 dbSNP
rs1269138486 1838 dbSNP
rs1218285028 1842 dbSNP
rs1168406085 1849 dbSNP
rs1398600198 1860 dbSNP
rs746488435 1868 dbSNP
rs1408170190 1875 dbSNP
rs941746177 1876 dbSNP
rs1375854329 1884 dbSNP
rs981467450 1885 dbSNP
rs556374475 1890 dbSNP
rs1027761072 1893 dbSNP
rs182941898 1894 dbSNP
rs1385031854 1897 dbSNP
rs1271252447 1898 dbSNP
rs1342032992 1901 dbSNP
rs917596960 1906 dbSNP
rs758358616 1910 dbSNP
rs1432777515 1911 dbSNP
rs993066406 1919 dbSNP
rs1289223216 1922 dbSNP
rs1455088339 1927 dbSNP
rs1347774582 1940 dbSNP
rs567327739 1941 dbSNP
rs1018696651 1944 dbSNP
rs1031839081 1945 dbSNP
rs1187280936 1947 dbSNP
rs1193225830 1948 dbSNP
rs553587101 1955 dbSNP
rs765085555 1957 dbSNP
rs969172381 1958 dbSNP
rs756945737 1966 dbSNP
rs1314975010 1975 dbSNP
rs888985555 1976 dbSNP
rs533805131 1979 dbSNP
rs1400382262 1981 dbSNP
rs1050302878 1992 dbSNP
rs935940839 1996 dbSNP
rs1319002541 1997 dbSNP
rs903841230 2000 dbSNP
rs1265115224 2003 dbSNP
rs1297596524 2008 dbSNP
rs1008082485 2011 dbSNP
rs889111918 2013 dbSNP
rs1030325888 2014 dbSNP
rs145996783 2015 dbSNP
rs142519847 2017 dbSNP
rs1263143777 2019 dbSNP
rs1444851308 2029 dbSNP
rs1187841867 2035 dbSNP
rs1036122058 2041 dbSNP
rs1455394048 2042 dbSNP
rs80065999 2042 dbSNP
rs531195762 2044 dbSNP
rs939495210 2048 dbSNP
rs1044801253 2051 dbSNP
rs947824115 2065 dbSNP
rs202170783 2068 dbSNP
rs1387225831 2081 dbSNP
rs926799841 2093 dbSNP
rs1341373141 2101 dbSNP
rs1320435643 2102 dbSNP
rs1372312571 2107 dbSNP
rs1443786236 2122 dbSNP
rs760885444 2126 dbSNP
rs917582966 2136 dbSNP
rs1296133193 2138 dbSNP
rs1239315920 2140 dbSNP
rs991861717 2146 dbSNP
rs981032199 2153 dbSNP
rs1365180155 2162 dbSNP
rs568879406 2167 dbSNP
rs775732833 2169 dbSNP
rs972145042 2170 dbSNP
rs968897064 2178 dbSNP
rs914756651 2185 dbSNP
rs1366960628 2205 dbSNP
rs986227310 2208 dbSNP
rs878953766 2211 dbSNP
rs190603176 2212 dbSNP
rs1428468381 2215 dbSNP
rs1455871893 2221 dbSNP
rs1030250587 2225 dbSNP
rs1395329697 2226 dbSNP
rs529017716 2231 dbSNP
rs1292363859 2232 dbSNP
rs1008641381 2248 dbSNP
rs1367332956 2255 dbSNP
rs1392389504 2256 dbSNP
rs1173111854 2260 dbSNP
rs888931555 2261 dbSNP
rs561289951 2262 dbSNP
rs1029272899 2263 dbSNP
rs1000090787 2268 dbSNP
rs904440768 2277 dbSNP
rs4687587 2294 dbSNP
rs1267081357 2299 dbSNP
rs945362084 2306 dbSNP
rs1264852315 2308 dbSNP
rs769087963 2310 dbSNP
rs1006573722 2314 dbSNP
rs887604792 2324 dbSNP
rs1045336828 2329 dbSNP
rs1204537499 2335 dbSNP
rs1418663170 2336 dbSNP
rs527942238 2337 dbSNP
rs1251852570 2339 dbSNP
rs1349852606 2344 dbSNP
rs896236987 2346 dbSNP
rs1369108146 2358 dbSNP
rs565587047 2360 dbSNP
rs1293599795 2362 dbSNP
rs1056541780 2365 dbSNP
rs1226166355 2368 dbSNP
rs1229482560 2377 dbSNP
rs939442843 2379 dbSNP
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rs975463351 5347 dbSNP
rs942830060 5348 dbSNP
rs1156694997 5353 dbSNP
rs4261872 5358 dbSNP
rs747919708 5363 dbSNP
rs912525385 5366 dbSNP
rs1268962640 5368 dbSNP
rs1045882939 5373 dbSNP
rs986773364 5382 dbSNP
rs1436588373 5387 dbSNP
rs1374742410 5388 dbSNP
rs1225786391 5393 dbSNP
rs1305328777 5393 dbSNP
rs1352445306 5394 dbSNP
rs139267150 5402 dbSNP
rs1293292855 5409 dbSNP
rs1489658843 5416 dbSNP
rs951299553 5417 dbSNP
rs1233337239 5418 dbSNP
rs1471127063 5429 dbSNP
rs781612090 5435 dbSNP
rs192628351 5443 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084078. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep2_AbnovaAb HITS-CLIP data was present in GSM1084068. RNA binding protein: AGO2. Condition:CLIP_noemetine_SigmaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

miRNA-target interactions (Provided by authors)
IDDuplex structurePosition
1
miRNA  3' guUUGUGGUAACAGUGUGAGGu 5'
            ::||||| |   :|||||| 
Target 5' auGGCACCACU---GCACUCCa 3'
3 - 21
Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084068
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_SigmaAb
Location of target site ENST00000315251.6 | 3UTR | UGAUGGCACCACUGCACUCCAGCCUGGGUGAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084078
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep2_AbnovaAb
Location of target site ENST00000315251.6 | 3UTR | UGAUGGCACCACUGCACUCCAGCCUGGGUGAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
MiRNA-Target Expression Profile (TCGA)
MiRNA Regulatory Network:
Functional analysis:
Strong evidence (reporter assay, western blot, qRT-PCR or qPCR) Other evidence
Transcription factor regulation Circular RNA sponge
534 hsa-miR-122-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT000012 CYP7A1 cytochrome P450 family 7 subfamily A member 1 3 1
MIRT000364 IGF1R insulin like growth factor 1 receptor 4 3
MIRT000365 SRF serum response factor 4 1
MIRT000663 RAC1 Rac family small GTPase 1 5 2
MIRT000717 RHOA ras homolog family member A 2 2
MIRT003006 CCNG1 cyclin G1 4 4
MIRT003079 GTF2B general transcription factor IIB 2 1
MIRT003080 GYS1 glycogen synthase 1 4 2
MIRT003081 ANK2 ankyrin 2 3 1
MIRT003082 NFATC2IP nuclear factor of activated T-cells 2 interacting protein 3 1
MIRT003083 ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 3 1
MIRT003084 ANXA11 annexin A11 4 2
MIRT003085 ALDOA aldolase, fructose-bisphosphate A 3 2
MIRT003086 RAB6B RAB6B, member RAS oncogene family 3 1
MIRT003087 RAB11FIP1 RAB11 family interacting protein 1 4 2
MIRT003088 FOXP1 forkhead box P1 3 1
MIRT003089 MECP2 methyl-CpG binding protein 2 3 2
MIRT003090 NCAM1 neural cell adhesion molecule 1 4 3
MIRT003091 UBAP2 ubiquitin associated protein 2 3 1
MIRT003092 TBX19 T-box 19 3 1
MIRT003093 AACS acetoacetyl-CoA synthetase 3 1
MIRT003094 DUSP2 dual specificity phosphatase 2 3 1
MIRT003095 ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 3 1
MIRT003097 MAPK11 mitogen-activated protein kinase 11 3 1
MIRT003098 FUNDC2 FUN14 domain containing 2 3 1
MIRT003099 AKT3 AKT serine/threonine kinase 3 3 3
MIRT003100 TPD52L2 tumor protein D52 like 2 4 3
MIRT003102 GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 4 2
MIRT003103 G6PC3 glucose-6-phosphatase catalytic subunit 3 4 2
MIRT003104 AP3M2 adaptor related protein complex 3 mu 2 subunit 3 1
MIRT003105 SLC7A1 solute carrier family 7 member 1 4 4
MIRT003106 XPO6 exportin 6 3 1
MIRT003107 FOXJ3 forkhead box J3 3 1
MIRT003108 SLC7A11 solute carrier family 7 member 11 3 1
MIRT003109 TRIB1 tribbles pseudokinase 1 3 1
MIRT003110 EGLN3 egl-9 family hypoxia inducible factor 3 3 1
MIRT003111 NUMBL NUMB like, endocytic adaptor protein 3 1
MIRT003112 ADAM17 ADAM metallopeptidase domain 17 3 5
MIRT003727 DSTYK dual serine/threonine and tyrosine protein kinase 3 2
MIRT003728 FAM117B family with sequence similarity 117 member B 3 1
MIRT004364 BCL2L2 BCL2 like 2 4 2
MIRT004527 PRKAB1 protein kinase AMP-activated non-catalytic subunit beta 1 2 1
MIRT004879 ADAM10 ADAM metallopeptidase domain 10 4 1
MIRT005782 ACVR1C activin A receptor type 1C 1 1
MIRT006123 PRKRA protein activator of interferon induced protein kinase EIF2AK2 4 1
MIRT006421 WNT1 Wnt family member 1 3 1
MIRT007007 PTPN1 protein tyrosine phosphatase, non-receptor type 1 1 1
MIRT007081 NT5C3A 5'-nucleotidase, cytosolic IIIA 1 1
MIRT007082 P4HA1 prolyl 4-hydroxylase subunit alpha 1 1 1
MIRT007083 ZNF395 zinc finger protein 395 1 1
MIRT007084 SOCS1 suppressor of cytokine signaling 1 1 1
MIRT023217 SSR3 signal sequence receptor subunit 3 1 1
MIRT023218 PHOX2A paired like homeobox 2a 1 1
MIRT023219 DZIP1L DAZ interacting zinc finger protein 1 like 1 1
MIRT023220 GSTM2 glutathione S-transferase mu 2 1 1
MIRT023221 RAI14 retinoic acid induced 14 1 1
MIRT023222 STARD13 StAR related lipid transfer domain containing 13 1 1
MIRT023223 CNN3 calponin 3 1 1
MIRT023224 A2M alpha-2-macroglobulin 1 1
MIRT023225 EFCAB6 EF-hand calcium binding domain 6 1 1
MIRT023226 GLOD4 glyoxalase domain containing 4 1 1
MIRT023227 CALR calreticulin 1 1
MIRT023228 POFUT1 protein O-fucosyltransferase 1 1 1
MIRT023229 PYGO1 pygopus family PHD finger 1 1 1
MIRT023230 CDY2B chromodomain Y-linked 2B 1 1
MIRT023231 CDC42EP3 CDC42 effector protein 3 1 1
MIRT023232 CS citrate synthase 2 2
MIRT023233 RNF170 ring finger protein 170 2 2
MIRT023234 GTF3C6 general transcription factor IIIC subunit 6 1 1
MIRT023235 ZNF321P zinc finger protein 321, pseudogene 1 1
MIRT023236 LAMP1 lysosomal associated membrane protein 1 1 1
MIRT023237 SLC52A2 solute carrier family 52 member 2 1 1
MIRT023238 ZNF658 zinc finger protein 658 1 1
MIRT023239 ATP13A3 ATPase 13A3 1 1
MIRT023240 CPNE5 copine 5 1 1
MIRT023241 KATNAL1 katanin catalytic subunit A1 like 1 1 1
MIRT023242 TMEM136 transmembrane protein 136 1 1
MIRT023243 ATP11A ATPase phospholipid transporting 11A 1 1
MIRT023244 TMEM74 transmembrane protein 74 1 1
MIRT023245 ANKRD10 ankyrin repeat domain 10 1 1
MIRT023246 TBL1XR1 transducin beta like 1 X-linked receptor 1 1 1
MIRT023247 USP10 ubiquitin specific peptidase 10 1 1
MIRT023248 AKAP11 A-kinase anchoring protein 11 1 1
MIRT023249 BACH2 BTB domain and CNC homolog 2 1 1
MIRT023250 HCCS holocytochrome c synthase 1 1
MIRT023251 Slc7a1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 1 1
MIRT023252 GTDC2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) 1 1
MIRT023253 CTPS1 CTP synthase 1 1 1
MIRT023254 SLC44A1 solute carrier family 44 member 1 1 1
MIRT023255 CLSPN claspin 1 1
MIRT023256 RABGEF1 RAB guanine nucleotide exchange factor 1 1 1
MIRT023257 FBXO7 F-box protein 7 1 1
MIRT023258 NCDN neurochondrin 1 1
MIRT023259 SOX2 SRY-box 2 1 1
MIRT023260 ZNF618 zinc finger protein 618 1 1
MIRT023261 ABLIM1 actin binding LIM protein 1 1 1
MIRT023262 ZBTB4 zinc finger and BTB domain containing 4 1 1
MIRT023263 LUZP1 leucine zipper protein 1 1 1
MIRT023264 NLGN3 neuroligin 3 1 1
MIRT023265 PRR11 proline rich 11 1 1
MIRT023266 HHAT hedgehog acyltransferase 1 1
MIRT023267 UBE2L3 ubiquitin conjugating enzyme E2 L3 1 1
MIRT023268 DNAJC18 DnaJ heat shock protein family (Hsp40) member C18 1 1
MIRT023269 FAM102A family with sequence similarity 102 member A 1 1
MIRT023270 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 1 1
MIRT023271 DENND2C DENN domain containing 2C 1 1
MIRT023272 HMOX1 heme oxygenase 1 3 2
MIRT023273 USP28 ubiquitin specific peptidase 28 1 1
MIRT023274 KRT18 keratin 18 1 1
MIRT023275 BPGM bisphosphoglycerate mutase 1 1
MIRT023276 ZNF233 zinc finger protein 233 1 1
MIRT023277 SLC25A30 solute carrier family 25 member 30 1 1
MIRT023278 ANKRD9 ankyrin repeat domain 9 2 2
MIRT023279 RLN1 relaxin 1 1 1
MIRT023280 DDIT3 DNA damage inducible transcript 3 1 1
MIRT023281 TRIM65 tripartite motif containing 65 1 1
MIRT023282 B4GALT1 beta-1,4-galactosyltransferase 1 1 1
MIRT023283 ANXA7 annexin A7 1 1
MIRT023284 SLC19A2 solute carrier family 19 member 2 1 1
MIRT023285 MARCKS myristoylated alanine rich protein kinase C substrate 1 1
MIRT023286 CLEC11A C-type lectin domain containing 11A 1 1
MIRT023287 CENPF centromere protein F 1 1
MIRT023288 CLDN18 claudin 18 1 1
MIRT023289 PFDN1 prefoldin subunit 1 1 1
MIRT023290 SPAG9 sperm associated antigen 9 1 1
MIRT023291 CEACAM8 carcinoembryonic antigen related cell adhesion molecule 8 1 1
MIRT023292 KRT10 keratin 10 1 1
MIRT023293 SET SET nuclear proto-oncogene 1 1
MIRT023294 SLC11A2 solute carrier family 11 member 2 1 1
MIRT023295 MYCBP MYC binding protein 2 2
MIRT023296 GPHB5 glycoprotein hormone beta 5 1 1
MIRT023297 STAU2 staufen double-stranded RNA binding protein 2 1 1
MIRT023298 NFATC1 nuclear factor of activated T-cells 1 1 1
MIRT023299 ERP29 endoplasmic reticulum protein 29 1 1
MIRT023300 MEP1A meprin A subunit alpha 1 1
MIRT023301 SPTLC1 serine palmitoyltransferase long chain base subunit 1 1 1
MIRT023302 GTF2H2 general transcription factor IIH subunit 2 1 1
MIRT023303 C14orf39 chromosome 14 open reading frame 39 1 1
MIRT023304 UBE2K ubiquitin conjugating enzyme E2 K 1 1
MIRT023305 PPP1R9B protein phosphatase 1 regulatory subunit 9B 1 1
MIRT023306 PSMD10 proteasome 26S subunit, non-ATPase 10 1 1
MIRT023307 CALD1 caldesmon 1 1 1
MIRT023308 TTYH3 tweety family member 3 1 1
MIRT023309 NMNAT2 nicotinamide nucleotide adenylyltransferase 2 1 1
MIRT023310 SCN4B sodium voltage-gated channel beta subunit 4 1 1
MIRT023311 C1orf122 chromosome 1 open reading frame 122 1 1
MIRT023312 PAK1 p21 (RAC1) activated kinase 1 1 1
MIRT023313 DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 1 1
MIRT023314 DMXL1 Dmx like 1 1 1
MIRT023315 ZNF160 zinc finger protein 160 1 1
MIRT023316 CSRP1 cysteine and glycine rich protein 1 1 1
MIRT023317 PHKA1 phosphorylase kinase regulatory subunit alpha 1 1 1
MIRT023318 RBBP5 RB binding protein 5, histone lysine methyltransferase complex subunit 1 1
MIRT023319 ANKRD13C ankyrin repeat domain 13C 1 1
MIRT023320 SUCLA2 succinate-CoA ligase ADP-forming beta subunit 1 1
MIRT023321 PEA15 phosphoprotein enriched in astrocytes 15 1 1
MIRT023322 MTPN myotrophin 1 1
MIRT023323 YKT6 YKT6 v-SNARE homolog 1 1
MIRT023324 MOB3B MOB kinase activator 3B 1 1
MIRT023325 FAM118A family with sequence similarity 118 member A 1 1
MIRT023326 ZNF264 zinc finger protein 264 1 1
MIRT023327 HECTD3 HECT domain E3 ubiquitin protein ligase 3 1 1
MIRT023328 BATF2 basic leucine zipper ATF-like transcription factor 2 1 1
MIRT023329 PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha 1 1
MIRT023330 MAPRE1 microtubule associated protein RP/EB family member 1 1 1
MIRT023331 TBC1D22B TBC1 domain family member 22B 1 1
MIRT023332 SLC9A1 solute carrier family 9 member A1 2 2
MIRT023333 NPEPPS aminopeptidase puromycin sensitive 1 1
MIRT023334 BCL2L1 BCL2 like 1 2 1
MIRT023335 OSMR oncostatin M receptor 1 1
MIRT023336 CALU calumenin 1 1
MIRT023337 BRI3BP BRI3 binding protein 1 1
MIRT023338 PSPH phosphoserine phosphatase 1 1
MIRT023339 APMAP adipocyte plasma membrane associated protein 1 1
MIRT023340 WASF1 WAS protein family member 1 1 1
MIRT023341 LCA5 LCA5, lebercilin 1 1
MIRT023342 NODAL nodal growth differentiation factor 1 1
MIRT023343 CASP7 caspase 7 1 1
MIRT023344 CPA3 carboxypeptidase A3 1 1
MIRT023345 PALM paralemmin 1 1
MIRT023346 TCP11 t-complex 11 1 1
MIRT023347 NALCN sodium leak channel, non-selective 1 1
MIRT023348 PLAGL2 PLAG1 like zinc finger 2 1 1
MIRT023349 IDS iduronate 2-sulfatase 2 2
MIRT023350 PARP11 poly(ADP-ribose) polymerase family member 11 1 1
MIRT023351 MAZ MYC associated zinc finger protein 1 1
MIRT023352 CPNE4 copine 4 1 1
MIRT023353 FAM19A3 family with sequence similarity 19 member A3, C-C motif chemokine like 1 1
MIRT023354 KRT14 keratin 14 1 1
MIRT023355 DYNC1H1 dynein cytoplasmic 1 heavy chain 1 1 1
MIRT023356 GNL3L G protein nucleolar 3 like 1 1
MIRT023357 HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1 1
MIRT023358 EYA4 EYA transcriptional coactivator and phosphatase 4 1 1
MIRT023359 GNPDA2 glucosamine-6-phosphate deaminase 2 1 1
MIRT023360 BRCA2 BRCA2, DNA repair associated 1 1
MIRT023361 ZSCAN4 zinc finger and SCAN domain containing 4 1 1
MIRT023362 HSPA5 heat shock protein family A (Hsp70) member 5 1 1
MIRT023363 SERAC1 serine active site containing 1 1 1
MIRT023364 SLC15A2 solute carrier family 15 member 2 1 1
MIRT023365 RABIF RAB interacting factor 1 1
MIRT023366 ART3 ADP-ribosyltransferase 3 1 1
MIRT023367 EP400 E1A binding protein p400 1 1
MIRT023368 MT4 metallothionein 4 1 1
MIRT023369 TRAM2 translocation associated membrane protein 2 1 1
MIRT023370 PHPT1 phosphohistidine phosphatase 1 1 1
MIRT023371 KIAA0101 PCNA clamp associated factor 1 1
MIRT023372 VHL von Hippel-Lindau tumor suppressor 1 1
MIRT023373 IFNA1 interferon alpha 1 1 1
MIRT023374 FSTL3 follistatin like 3 1 1
MIRT023375 PHF14 PHD finger protein 14 1 1
MIRT023376 ZCCHC2 zinc finger CCHC-type containing 2 1 1
MIRT023377 GSTM3 glutathione S-transferase mu 3 1 1
MIRT023378 DCTN5 dynactin subunit 5 1 1
MIRT023379 CHST3 carbohydrate sulfotransferase 3 1 1
MIRT023380 HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 1 1
MIRT023381 ADO 2-aminoethanethiol dioxygenase 1 1
MIRT023382 POMZP3 POM121 and ZP3 fusion 1 1
MIRT023383 CHST12 carbohydrate sulfotransferase 12 1 1
MIRT023384 ARSB arylsulfatase B