miRTarBase - #MIRT002310


—
pre-miRNA Information
pre-miRNA hsa-mir-29b-1   
Genomic Coordinates chr7: 130877459 - 130877539
Synonyms MIRN29B1, miRNA29B1, MIR29B1
Description Homo sapiens miR-29b-1 stem-loop
Comment Mourelatos et al. identified two copies of this sequence mapping to chromosome 7, and assigned the names mir-102-7.1 and mir-102-7.2 . Subsequent genome assemblies suggest the presence of only one miR-102 locus on chromosome 7. Human miR-102 is a homologue of mouse miR-29b (MIR:MI0000143) and so has been renamed here for consistency.
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-mir-29b-2   
Genomic Coordinates chr1: 207802443 - 207802523
Synonyms MIRN29B2, mir-29b-2, MIR29B2
Description Homo sapiens miR-29b-2 stem-loop
Comment This sequence was named mir-102-1 in reference . Human miR-102 is a homologue of mouse miR-29b (MIR:MI0000143) and so has been renamed here for consistency.
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-29b-3p
Sequence 52| UAGCACCAUUUGAAAUCAGUGUU |74
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 2 7 - 130877488 29233923 MiREDiBase
A-to-I 2 1 - 207802471 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs773555186 20 dbSNP
rs1390817128 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SFPQ   
Synonyms POMP100, PPP1R140, PSF
Description splicing factor proline and glutamine rich
Transcript NM_005066   
Expression
Putative miRNA Targets on SFPQ
3'UTR of SFPQ
(miRNA target sites are highlighted)		 
>SFPQ|NM_005066|3'UTR
   1 ATGTGATATTTAGGCTTTCATTCCAGTTTGTTTTGTTTTTTTGTTTAGATACCAATCTTTTAAATTCTTGCATTTTAGTA
  81 AGAAAGCTATCTTTTTATGGATGTTAGCAGTTTATTGACCTAATATTTGTAAATGGTCTGTTTGGGCAGGTAAAATTATG
 161 TAATGCAGTGTTTGGAACAGGAGAATTTTTTTTTCCTTTTTATTTCTTTATTTTTTCTTTTTTACTGTATAATGTCCCTC
 241 AAGTTTATGGCAGTGTACCTTGTGCCACTGAATTTCCAAAGTGTACCAATTTTTTTTTTTTTACTGTGCTTCAAATAAAT
 321 AGAAAAATAGTTATAATATTGATCTTCAACTTTGCCATTCATGCTTCTATGCATATTAGGCTACGTATTCCACATTGAAA
 401 GCATGAGAGTGTCTAGGCCTTTGAATGGCATATGCCATTTCTGGGAAATGCATCTGGAGGCTAAGTATTGCTTTCTACAA
 481 ATAATTGCCCCCTTTGTTTTAAAAAGAAGAAATGCATATTGAAGTAGTTTGATGATTTGTTTGGCATATAGGAAGCACGC
 561 TGGTGCTAAGTATTTTTTAAATGGTTATGTAAGCAAAGCTGAACTGTAAATCTTCAGGAATATGTATTAAGATTGTGGAA
 641 TGGGTGTAAGACAATTGGTAGGGGGTGAAAGTGGGTTTGATTAAATGGATCTTTTATGGCCCTATGATCTATCCTTTACT
 721 TGAAAGCTTTTGAAAAGTGGAAAGGTCATTTTGTTGCATTTCCCCATTTCTTGTTTTTAAAAGACCAACAAATCTCAAGC
 801 CCTATAAATGGCTTGTATTGAACTTTTACATTTGAATTAAAGATGTTAAACATGAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuGUGACUAAAGU-UUACCACGAu 5'
            :|: |:   || : ||||||| 
Target 5' caTATAGGAAGCACGCTGGTGCTa 3'
 545 - 568 141.00 -12.50
2 
miRNA  3' uugugacUAAA-GUUUACCACGAu 5'
                 |||| :||||||| || 
Target 5' acctaatATTTGTAAATGGT-CTg 3'
 118 - 140 116.00 -10.30
3 
miRNA  3' uugUGACUA-AAGUUUACC-ACGAu 5'
             :|| || ||:  |||| ||:| 
Target 5' aaaGCT-ATCTTTTTATGGATGTTa 3'
 83 - 106 107.00 -7.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30504379 11 COSMIC
COSN28843240 35 COSMIC
COSN19615393 55 COSMIC
COSN31556572 64 COSMIC
COSN30148163 67 COSMIC
COSN19487727 71 COSMIC
COSN20090201 140 COSMIC
COSN30143972 147 COSMIC
COSN31524714 153 COSMIC
COSN30509992 158 COSMIC
COSN31530437 183 COSMIC
COSN22878989 185 COSMIC
COSN28870800 186 COSMIC
COSN29985974 195 COSMIC
COSN31605727 206 COSMIC
COSN28193556 210 COSMIC
COSN20094698 244 COSMIC
COSN31593863 280 COSMIC
COSN27346806 290 COSMIC
COSN31538185 304 COSMIC
COSN31556665 308 COSMIC
COSN31487673 333 COSMIC
COSN31566326 377 COSMIC
COSN26586072 454 COSMIC
COSN31563405 648 COSMIC
COSN31486892 657 COSMIC
COSN28637169 722 COSMIC
COSN30174056 732 COSMIC
COSN31526941 790 COSMIC
COSN30028088 960 COSMIC
COSN21718484 1217 COSMIC
COSN21457070 1381 COSMIC
COSN20568735 1400 COSMIC
COSN20569140 1411 COSMIC
COSN26796920 1485 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs764093695 1 dbSNP
rs1376854521 2 dbSNP
rs1015678949 5 dbSNP
rs760737686 6 dbSNP
rs775602537 7 dbSNP
rs897816529 8 dbSNP
rs1424302196 9 dbSNP
rs1192900596 15 dbSNP
rs766279751 18 dbSNP
rs1259720394 19 dbSNP
rs762835711 20 dbSNP
rs1418147697 25 dbSNP
rs773891977 26 dbSNP
rs769495425 31 dbSNP
rs770406589 33 dbSNP
rs747783087 35 dbSNP
rs764748226 35 dbSNP
rs200083471 38 dbSNP
rs777123036 38 dbSNP
rs768908972 40 dbSNP
rs78648707 42 dbSNP
rs758604468 43 dbSNP
rs780158262 43 dbSNP
rs1217358852 46 dbSNP
rs996993027 47 dbSNP
rs375041933 48 dbSNP
rs370466742 50 dbSNP
rs3768339 55 dbSNP
rs944271852 57 dbSNP
rs565451246 61 dbSNP
rs1314389842 62 dbSNP
rs568697804 62 dbSNP
rs188912845 66 dbSNP
rs1234629740 70 dbSNP
rs913900705 71 dbSNP
rs1429721820 76 dbSNP
rs1273506959 77 dbSNP
rs1420175819 77 dbSNP
rs1232986755 83 dbSNP
rs1327328129 85 dbSNP
rs72908970 87 dbSNP
rs1398653988 88 dbSNP
rs936755746 89 dbSNP
rs958831931 94 dbSNP
rs1034278706 99 dbSNP
rs1293218666 101 dbSNP
rs925382147 106 dbSNP
rs980841748 107 dbSNP
rs183974568 110 dbSNP
rs1313538840 111 dbSNP
rs915753815 117 dbSNP
rs1372184297 123 dbSNP
rs1416439158 126 dbSNP
rs992664875 131 dbSNP
rs1463070480 138 dbSNP
rs1400312801 142 dbSNP
rs1164193731 145 dbSNP
rs1025512524 153 dbSNP
rs960271785 158 dbSNP
rs1418243240 165 dbSNP
rs993553543 173 dbSNP
rs1179103383 175 dbSNP
rs897930646 183 dbSNP
rs1477582293 184 dbSNP
rs1015253542 185 dbSNP
rs549797350 186 dbSNP
rs1424021403 187 dbSNP
rs1195808276 190 dbSNP
rs1337554757 194 dbSNP
rs1040360248 195 dbSNP
rs1274298425 195 dbSNP
rs1304428967 197 dbSNP
rs535909008 197 dbSNP
rs889152253 202 dbSNP
rs554331611 205 dbSNP
rs1324601756 206 dbSNP
rs1377089271 206 dbSNP
rs1261909651 209 dbSNP
rs1396631446 214 dbSNP
rs1050698523 217 dbSNP
rs1452795954 218 dbSNP
rs1361792001 220 dbSNP
rs1161630431 227 dbSNP
rs936275988 233 dbSNP
rs748011205 236 dbSNP
rs1252500393 238 dbSNP
rs200471157 244 dbSNP
rs1443573061 246 dbSNP
rs3835700 247 dbSNP
rs397841092 247 dbSNP
rs386630285 249 dbSNP
rs569929139 253 dbSNP
rs1340543444 258 dbSNP
rs1204996348 271 dbSNP
rs977570329 274 dbSNP
rs1262856254 289 dbSNP
rs1280460651 295 dbSNP
rs11542799 296 dbSNP
rs1302181887 303 dbSNP
rs1324141889 303 dbSNP
rs1353947476 303 dbSNP
rs1382600631 303 dbSNP
rs796763714 303 dbSNP
rs1491298328 304 dbSNP
rs1491180090 305 dbSNP
rs1340439415 306 dbSNP
rs945774081 308 dbSNP
rs1450304490 309 dbSNP
rs548625887 314 dbSNP
rs530174911 322 dbSNP
rs952478044 327 dbSNP
rs1378261110 330 dbSNP
rs992868943 330 dbSNP
rs1333783135 334 dbSNP
rs1445747391 334 dbSNP
rs1026704912 335 dbSNP
rs958391651 337 dbSNP
rs996604276 338 dbSNP
rs559889169 339 dbSNP
rs899959756 343 dbSNP
rs573384308 347 dbSNP
rs113198318 349 dbSNP
rs532587285 357 dbSNP
rs892738766 364 dbSNP
rs1279167981 369 dbSNP
rs565508850 372 dbSNP
rs1349497032 373 dbSNP
rs1274925483 380 dbSNP
rs1226663350 383 dbSNP
rs761095116 384 dbSNP
rs754992414 394 dbSNP
rs984036158 395 dbSNP
rs1297584944 396 dbSNP
rs1052427396 403 dbSNP
rs1400387846 408 dbSNP
rs1374558695 410 dbSNP
rs1172535159 412 dbSNP
rs936643270 415 dbSNP
rs375071701 416 dbSNP
rs1436809212 420 dbSNP
rs1403049315 422 dbSNP
rs1422831201 427 dbSNP
rs1025460112 429 dbSNP
rs1182314832 432 dbSNP
rs543736104 433 dbSNP
rs1474441333 434 dbSNP
rs994004340 437 dbSNP
rs1194949565 440 dbSNP
rs576695055 441 dbSNP
rs1255833841 446 dbSNP
rs1473504096 448 dbSNP
rs115174762 451 dbSNP
rs115809018 452 dbSNP
rs948143269 454 dbSNP
rs1336802814 455 dbSNP
rs915742470 465 dbSNP
rs1438027721 469 dbSNP
rs1260461130 477 dbSNP
rs992656643 479 dbSNP
rs1219149661 486 dbSNP
rs1354654346 490 dbSNP
rs3768338 491 dbSNP
rs1291173648 492 dbSNP
rs889105523 495 dbSNP
rs571762075 496 dbSNP
rs868838925 498 dbSNP
rs1274367803 501 dbSNP
rs1408284749 501 dbSNP
rs1172089111 502 dbSNP
rs1000373238 503 dbSNP
rs1190538377 506 dbSNP
rs1377119693 506 dbSNP
rs1416197739 506 dbSNP
rs553448250 506 dbSNP
rs982730674 509 dbSNP
rs1237700092 512 dbSNP
rs1473306447 512 dbSNP
rs1283651931 514 dbSNP
rs1443275282 516 dbSNP
rs1435627039 518 dbSNP
rs759698809 532 dbSNP
rs904800546 537 dbSNP
rs1041827181 543 dbSNP
rs1334039794 546 dbSNP
rs1229855276 549 dbSNP
rs1356708467 549 dbSNP
rs1279206418 551 dbSNP
rs1379388569 551 dbSNP
rs115671852 552 dbSNP
rs571340612 553 dbSNP
rs770918315 555 dbSNP
rs556353804 558 dbSNP
rs1440887200 562 dbSNP
rs1399208914 563 dbSNP
rs749329192 565 dbSNP
rs1165431747 566 dbSNP
rs537724548 571 dbSNP
rs963822327 572 dbSNP
rs1392956369 582 dbSNP
rs1167644508 586 dbSNP
rs552741792 587 dbSNP
rs1056878950 592 dbSNP
rs937108807 592 dbSNP
rs1468252844 595 dbSNP
rs1239514895 600 dbSNP
rs1178742341 612 dbSNP
rs1019780832 614 dbSNP
rs1467609013 615 dbSNP
rs1251072286 622 dbSNP
rs1223606898 631 dbSNP
rs926950806 633 dbSNP
rs374738445 639 dbSNP
rs1222323381 642 dbSNP
rs952567768 647 dbSNP
rs918515150 649 dbSNP
rs892651688 654 dbSNP
rs548554858 665 dbSNP
rs1176338083 666 dbSNP
rs530112309 680 dbSNP
rs1437795769 691 dbSNP
rs1001133145 698 dbSNP
rs1247615695 702 dbSNP
rs1008971668 704 dbSNP
rs1158807511 709 dbSNP
rs953599306 710 dbSNP
rs566117791 711 dbSNP
rs547893201 713 dbSNP
rs1227383802 714 dbSNP
rs1000152345 721 dbSNP
rs1201943050 726 dbSNP
rs1320431012 727 dbSNP
rs532667232 732 dbSNP
rs1241356061 737 dbSNP
rs1213412672 739 dbSNP
rs1224410057 740 dbSNP
rs1287026671 745 dbSNP
rs1323168394 747 dbSNP
rs193047652 757 dbSNP
rs1045083859 758 dbSNP
rs188729830 768 dbSNP
rs749007193 770 dbSNP
rs1041943894 773 dbSNP
rs904748126 773 dbSNP
rs182747612 774 dbSNP
rs896605503 781 dbSNP
rs1402250190 786 dbSNP
rs1375933735 787 dbSNP
rs1010484277 794 dbSNP
rs1433711275 795 dbSNP
rs1293878527 796 dbSNP
rs1056878093 802 dbSNP
rs1438600905 805 dbSNP
rs1414496170 808 dbSNP
rs1348046491 818 dbSNP
rs190128743 826 dbSNP
rs1057490713 827 dbSNP
rs1478713186 829 dbSNP
rs1381575651 830 dbSNP
rs1263623396 832 dbSNP
rs1156492604 842 dbSNP
rs908377666 844 dbSNP
rs1047382175 845 dbSNP
rs139962757 854 dbSNP
rs758176371 869 dbSNP
rs1193280571 871 dbSNP
rs571698294 872 dbSNP
rs1246649678 873 dbSNP
rs963771610 880 dbSNP
rs912290875 882 dbSNP
rs918298513 888 dbSNP
rs986579237 891 dbSNP
rs1304183866 892 dbSNP
rs145015385 894 dbSNP
rs1353400720 902 dbSNP
rs965319522 910 dbSNP
rs1467092078 912 dbSNP
rs538339314 912 dbSNP
rs912371351 916 dbSNP
rs1163970613 921 dbSNP
rs1474078804 923 dbSNP
rs1258540805 925 dbSNP
rs985713405 928 dbSNP
rs1480383850 932 dbSNP
rs747286844 933 dbSNP
rs1031172823 934 dbSNP
rs1231250019 937 dbSNP
rs1201117906 940 dbSNP
rs1348857940 941 dbSNP
rs1001523462 942 dbSNP
rs968305859 943 dbSNP
rs1023581702 944 dbSNP
rs1220746055 947 dbSNP
rs1323817979 948 dbSNP
rs185469006 949 dbSNP
rs1396244231 950 dbSNP
rs1372032718 954 dbSNP
rs1274208647 959 dbSNP
rs1448283860 964 dbSNP
rs554606319 967 dbSNP
rs1400975874 980 dbSNP
rs577692484 984 dbSNP
rs1325059978 987 dbSNP
rs1400493065 995 dbSNP
rs1456214031 995 dbSNP
rs1369968901 996 dbSNP
rs556051979 998 dbSNP
rs779968284 999 dbSNP
rs556663760 1001 dbSNP
rs1418695159 1007 dbSNP
rs1295797273 1009 dbSNP
rs1378600697 1009 dbSNP
rs182303961 1010 dbSNP
rs968686818 1018 dbSNP
rs1359384437 1019 dbSNP
rs1177712749 1022 dbSNP
rs1212350328 1025 dbSNP
rs527598152 1036 dbSNP
rs1266368435 1045 dbSNP
rs573799139 1048 dbSNP
rs1306578241 1049 dbSNP
rs1315989797 1049 dbSNP
rs190933972 1063 dbSNP
rs1046923880 1065 dbSNP
rs1325208248 1066 dbSNP
rs1385003011 1066 dbSNP
rs1392668244 1072 dbSNP
rs1293879385 1073 dbSNP
rs1452728835 1075 dbSNP
rs1358903897 1081 dbSNP
rs534113855 1082 dbSNP
rs1215983757 1089 dbSNP
rs566056866 1093 dbSNP
rs374508458 1094 dbSNP
rs370214754 1098 dbSNP
rs1268608243 1101 dbSNP
rs149937201 1110 dbSNP
rs536221796 1113 dbSNP
rs1208225390 1114 dbSNP
rs986918122 1116 dbSNP
rs1310252504 1117 dbSNP
rs1262245943 1125 dbSNP
rs1353883052 1127 dbSNP
rs1302025244 1132 dbSNP
rs1035824364 1137 dbSNP
rs965576085 1138 dbSNP
rs956521563 1140 dbSNP
rs924097183 1143 dbSNP
rs1381447366 1154 dbSNP
rs866864336 1155 dbSNP
rs1338080196 1156 dbSNP
rs906067007 1158 dbSNP
rs1276149876 1161 dbSNP
rs979655697 1170 dbSNP
rs547834265 1171 dbSNP
rs1023820652 1174 dbSNP
rs1467613118 1176 dbSNP
rs1378723545 1179 dbSNP
rs1193025191 1181 dbSNP
rs1464200013 1182 dbSNP
rs1012468108 1183 dbSNP
rs896814053 1185 dbSNP
rs960653602 1189 dbSNP
rs1488400824 1190 dbSNP
rs1198265740 1204 dbSNP
rs1036713408 1205 dbSNP
rs1226597721 1209 dbSNP
rs1338192579 1210 dbSNP
rs1035065280 1211 dbSNP
rs1400325164 1213 dbSNP
rs571886437 1213 dbSNP
rs1171820149 1215 dbSNP
rs1467707818 1216 dbSNP
rs1422118609 1217 dbSNP
rs943944161 1222 dbSNP
rs912469007 1223 dbSNP
rs985276029 1225 dbSNP
rs1167916773 1228 dbSNP
rs1464493787 1229 dbSNP
rs1171858813 1231 dbSNP
rs1491405219 1231 dbSNP
rs776963224 1231 dbSNP
rs78294528 1231 dbSNP
rs796105438 1231 dbSNP
rs147051144 1232 dbSNP
rs749351606 1232 dbSNP
rs1316010361 1233 dbSNP
rs200831313 1233 dbSNP
rs758281883 1233 dbSNP
rs774039226 1233 dbSNP
rs1483036190 1235 dbSNP
rs886552136 1236 dbSNP
rs1047317667 1237 dbSNP
rs538722423 1239 dbSNP
rs1341188442 1240 dbSNP
rs1444595506 1242 dbSNP
rs1403131472 1245 dbSNP
rs898342952 1249 dbSNP
rs571722132 1253 dbSNP
rs1461263538 1254 dbSNP
rs1020212872 1255 dbSNP
rs1161134840 1256 dbSNP
rs114634491 1258 dbSNP
rs890793609 1264 dbSNP
rs960285331 1264 dbSNP
rs1321833727 1265 dbSNP
rs1239952990 1272 dbSNP
rs1050816500 1275 dbSNP
rs1199177604 1278 dbSNP
rs906009547 1280 dbSNP
rs1230293230 1285 dbSNP
rs1027186371 1296 dbSNP
rs1393989164 1297 dbSNP
rs531931060 1298 dbSNP
rs1238068570 1299 dbSNP
rs1053946 1301 dbSNP
rs1310708681 1304 dbSNP
rs1381584490 1306 dbSNP
rs1440818061 1311 dbSNP
rs1331531063 1315 dbSNP
rs995228511 1323 dbSNP
rs1325967036 1325 dbSNP
rs1406275329 1328 dbSNP
rs1391004639 1330 dbSNP
rs1157613894 1333 dbSNP
rs935063442 1336 dbSNP
rs923739310 1338 dbSNP
rs1036657987 1341 dbSNP
rs561188193 1342 dbSNP
rs372710318 1352 dbSNP
rs71638655 1352 dbSNP
rs575872799 1362 dbSNP
rs1244860124 1368 dbSNP
rs890829759 1368 dbSNP
rs549250773 1374 dbSNP
rs932608323 1376 dbSNP
rs946858539 1380 dbSNP
rs916748273 1397 dbSNP
rs1214712998 1398 dbSNP
rs528009967 1402 dbSNP
rs1286794634 1414 dbSNP
rs1218670202 1417 dbSNP
rs1366149426 1424 dbSNP
rs960976290 1425 dbSNP
rs979247491 1428 dbSNP
rs1035417364 1432 dbSNP
rs185835547 1433 dbSNP
rs537045387 1440 dbSNP
rs1361958911 1453 dbSNP
rs1236099157 1458 dbSNP
rs1158751145 1481 dbSNP
rs1413367460 1484 dbSNP
rs1422980717 1488 dbSNP
rs913327024 1491 dbSNP
rs1478269244 1497 dbSNP
rs950795672 1500 dbSNP
rs988946549 1500 dbSNP
rs865913563 1502 dbSNP
rs74395940 1503 dbSNP
rs1053947 1504 dbSNP
rs994929816 1506 dbSNP
rs898293732 1509 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions 293
Location of target site 3'UTR
Tools used in this research miRanda , PicTar , TargetScan
Original Description (Extracted from the article) ... The full-length 3'UTR of sfpq was fused to firefly luciferase. //Inhibitors against miR-29b and miR-141 were co-transfected ...

- Beitzinger M; Peters L; Zhu JY; Kremmer E; et al., 2007, RNA biology.

Article - Beitzinger M; Peters L; Zhu JY; Kremmer E; et al.
- RNA biology, 2007
MicroRNAs (miRNAs) constitute a class of small non-coding RNAs that regulate gene expression on the level of translation and/or mRNA stability. Mammalian miRNAs associate with members of the Argonaute (Ago) protein family and bind to partially complementary sequences in the 3' untranslated region (UTR) of specific target mRNAs. Computer algorithms based on factors such as free binding energy or sequence conservation have been used to predict miRNA target mRNAs. Based on such predictions, up to one third of all mammalian mRNAs seem to be under miRNA regulation. However, due to the low degree of complementarity between the miRNA and its target, such computer programs are often imprecise and therefore not very reliable. Here we report the first biochemical identification approach of miRNA targets from human cells. Using highly specific monoclonal antibodies against members of the Ago protein family, we co-immunoprecipitate Ago-bound mRNAs and identify them by cloning. Interestingly, most of the identified targets are also predicted by different computer programs. Moreover, we randomly analyzed six different target candidates and were able to experimentally validate five as miRNA targets. Our data clearly indicate that miRNA targets can be experimentally identified from Ago complexes and therefore provide a new tool to directly analyze miRNA function.
LinkOut: [PMID: 17637574]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer -0.437 1.6e-2 -0.317 6.6e-2 24 Click to see details
GSE19536 Breast cancer 0.181 3.6e-2 0.153 6.4e-2 100 Click to see details
GSE21687 Ependynoma primary tumors -0.213 4.6e-2 -0.148 1.2e-1 64 Click to see details
GSE19783 ER- ER- breast cancer 0.166 7.2e-2 0.087 2.2e-1 79 Click to see details
GSE17306 Multiple myeloma 0.18 1.1e-1 0.216 6.8e-2 49 Click to see details
GSE19350 CNS germ cell tumors 0.38 1.1e-1 0.280 1.9e-1 12 Click to see details
GSE17498 Multiple myeloma 0.195 1.1e-1 0.218 8.8e-2 40 Click to see details
GSE15076 Monocyte-derived dendritic cells -0.572 1.2e-1 -0.714 5.5e-2 6 Click to see details
GSE35602 Colorectal cancer stromal tissue 0.238 1.3e-1 0.176 2.0e-1 25 Click to see details
GSE32688 Pancreatic cancer -0.202 1.3e-1 -0.102 2.9e-1 32 Click to see details
GSE28260 Renal cortex and medulla -0.3 1.6e-1 -0.236 2.2e-1 13 Click to see details
GSE27834 Pluripotent stem cells 0.256 1.7e-1 -0.147 2.9e-1 16 Click to see details
GSE38226 Liver fibrosis 0.208 1.8e-1 0.068 3.8e-1 21 Click to see details
GSE42095 Differentiated embryonic stem cells 0.183 2.0e-1 0.177 2.1e-1 23 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.131 2.9e-1 0.008 4.9e-1 20 Click to see details
GSE21032 Prostate cancer 0.051 3.2e-1 0.023 4.2e-1 83 Click to see details
GSE26953 Aortic valvular endothelial cells -0.06 3.9e-1 -0.118 2.9e-1 24 Click to see details
GSE14794 Lymphoblastoid cells -0.028 4.0e-1 0.045 3.4e-1 90 Click to see details
GSE21849 B cell lymphoma 0.049 4.0e-1 0.012 4.8e-1 29 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.045 4.2e-1 0.020 4.6e-1 25 Click to see details
GSE19783 ER+ ER+ breast cancer 0.002 5.0e-1 0.230 1.6e-1 20 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
ESCA -0.453 0.08 -0.445 0.09 11 Click to see details
LUAD 0.35 0.13 0.455 0.07 12 Click to see details
LUSC -0.175 0.15 -0.210 0.1 38 Click to see details
BRCA -0.103 0.18 -0.107 0.17 84 Click to see details
UCEC -0.186 0.22 -0.175 0.24 19 Click to see details
STAD 0.107 0.28 0.125 0.25 32 Click to see details
CHOL -0.174 0.33 -0.033 0.47 9 Click to see details
HNSC -0.071 0.33 -0.127 0.21 42 Click to see details
CESC 0.506 0.33 0.500 0.33 3 Click to see details
KIRP -0.076 0.34 -0.079 0.33 32 Click to see details
BLCA 0.096 0.35 0.251 0.16 18 Click to see details
PAAD 0.284 0.36 0.200 0.4 4 Click to see details
COAD -0.146 0.37 -0.095 0.41 8 Click to see details
LIHC 0.04 0.39 0.027 0.43 49 Click to see details
KICH -0.047 0.41 -0.051 0.4 25 Click to see details
PRAD 0.019 0.45 0.016 0.46 50 Click to see details
THCA 0.009 0.47 0.037 0.39 59 Click to see details
PCPG 0.079 0.47 0.500 0.33 3 Click to see details
KIRC 0.006 0.48 0.076 0.27 68 Click to see details
KIRC 0.006 0.48 0.076 0.27 68 Click to see details
KIRC 0.006 0.48 0.076 0.27 68 Click to see details
248 hsa-miR-29b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT000095 TGFB3 transforming growth factor beta 3 2 1
MIRT000096 HDAC4 histone deacetylase 4 4 4
MIRT000097 CTNNBIP1 catenin beta interacting protein 1 4 4
MIRT000098 COL5A3 collagen type V alpha 3 chain 2 2
MIRT000099 COL4A2 collagen type IV alpha 2 chain 2 2
MIRT000100 COL1A1 collagen type I alpha 1 chain 8 8
MIRT000101 ACVR2A activin A receptor type 2A 1 1
MIRT000445 SP1 Sp1 transcription factor 5 6
MIRT000684 CDK6 cyclin dependent kinase 6 6 5
MIRT000930 BACE1 beta-secretase 1 3 1
MIRT002310 SFPQ splicing factor proline and glutamine rich 3 1
MIRT002316 DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 3 1
MIRT003026 DNMT3B DNA methyltransferase 3 beta 4 7
MIRT003029 DNMT3A DNA methyltransferase 3 alpha 5 9
MIRT003287 MCL1 MCL1, BCL2 family apoptosis regulator 7 20
MIRT003290 BCL2 BCL2, apoptosis regulator 4 3
MIRT003661 DNMT1 DNA methyltransferase 1 4 2
MIRT003736 S100B S100 calcium binding protein B 3 1
MIRT003813 VEGFA vascular endothelial growth factor A 9 9
MIRT004308 ESR1 estrogen receptor 1 2 1
MIRT004312 NCOA3 nuclear receptor coactivator 3 2 1
MIRT004419 TET1 tet methylcytosine dioxygenase 1 4 2
MIRT004510 TCL1A T-cell leukemia/lymphoma 1A 5 4
MIRT005381 Mmp15 matrix metallopeptidase 15 3 1
MIRT005383 MMP15 matrix metallopeptidase 15 2 1
MIRT005385 MMP24 matrix metallopeptidase 24 4 2
MIRT005387 Mmp24 matrix metallopeptidase 24 2 1
MIRT005486 GRN granulin precursor 4 1
MIRT005522 FGG fibrinogen gamma chain 2 1
MIRT005533 FGA fibrinogen alpha chain 2 1
MIRT005534 FGB fibrinogen beta chain 2 1
MIRT005567 COL3A1 collagen type III alpha 1 chain 5 4
MIRT005568 COL4A1 collagen type IV alpha 1 chain 7 9
MIRT005570 MMP2 matrix metallopeptidase 2 5 8
MIRT005614 BBC3 BCL2 binding component 3 2 2
MIRT005667 ADAM12 ADAM metallopeptidase domain 12 5 3
MIRT005669 NID1 nidogen 1 4 1
MIRT006054 HMGA2 high mobility group AT-hook 2 3 1
MIRT006058 TGFB2 transforming growth factor beta 2 3 2
MIRT006059 TGFB1 transforming growth factor beta 1 2 1
MIRT006060 BMP1 bone morphogenetic protein 1 3 2
MIRT006098 PTEN phosphatase and tensin homolog 7 3
MIRT006251 NASP nuclear autoantigenic sperm protein 2 1
MIRT006486 PPP1R13B protein phosphatase 1 regulatory subunit 13B 2 1
MIRT006488 CDC42 cell division cycle 42 4 2
MIRT006753 GSK3B glycogen synthase kinase 3 beta 1 1
MIRT006815 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 3 1
MIRT006915 NKIRAS2 NFKB inhibitor interacting Ras like 2 5 3
MIRT007011 RAX retina and anterior neural fold homeobox 2 1
MIRT007033 TBX21 T-box 21 1 1
MIRT007034 IFNG interferon gamma 1 1
MIRT007102 DUSP2 dual specificity phosphatase 2 3 3
MIRT007254 FOS Fos proto-oncogene, AP-1 transcription factor subunit 3 3
MIRT027237 PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 2 2
MIRT027238 IMPDH1 inosine monophosphate dehydrogenase 1 2 2
MIRT027239 MYCN MYCN proto-oncogene, bHLH transcription factor 3 3
MIRT048359 SCAF8 SR-related CTD associated factor 8 1 1
MIRT048360 CLDN1 claudin 1 1 1
MIRT048361 MRPS35 mitochondrial ribosomal protein S35 1 1
MIRT048362 RSL24D1 ribosomal L24 domain containing 1 1 1
MIRT048363 LRP10 LDL receptor related protein 10 1 1
MIRT048364 HP1BP3 heterochromatin protein 1 binding protein 3 1 1
MIRT048365 B4GALT5 beta-1,4-galactosyltransferase 5 1 1
MIRT048366 KIAA1671 KIAA1671 1 1
MIRT048367 NNT nicotinamide nucleotide transhydrogenase 1 1
MIRT048368 IFIH1 interferon induced with helicase C domain 1 1 1
MIRT048369 TPT1 tumor protein, translationally-controlled 1 1 1
MIRT048370 RUNDC3B RUN domain containing 3B 1 1
MIRT048371 CECR2 CECR2, histone acetyl-lysine reader 1 1
MIRT048372 TPD52L2 tumor protein D52 like 2 1 1
MIRT048373 NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit 1 1
MIRT048374 CIT citron rho-interacting serine/threonine kinase 1 1
MIRT048375 GNB2L1 receptor for activated C kinase 1 1 1
MIRT048376 SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 1 1
MIRT048377 PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 1 1
MIRT048378 PIGN phosphatidylinositol glycan anchor biosynthesis class N 1 1
MIRT048379 RPS4X ribosomal protein S4, X-linked 1 1
MIRT048380 CCSAP centriole, cilia and spindle associated protein 1 1
MIRT048381 CALU calumenin 1 1
MIRT048382 NREP neuronal regeneration related protein 1 1
MIRT048383 MKI67 marker of proliferation Ki-67 1 1
MIRT053293 TDG thymine DNA glycosylase 5 5
MIRT053581 CCND2 cyclin D2 5 3
MIRT053738 COL4A5 collagen type IV alpha 5 chain 1 1
MIRT053739 COL7A1 collagen type VII alpha 1 chain 1 1
MIRT053740 COL15A1 collagen type XV alpha 1 chain 1 1
MIRT053741 COL2A1 collagen type II alpha 1 chain 1 1
MIRT053742 COL4A6 collagen type IV alpha 6 chain 1 1
MIRT053743 CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 1 1
MIRT053744 SOX12 SRY-box 12 1 1
MIRT053745 MAP2K6 mitogen-activated protein kinase kinase 6 1 1
MIRT053746 TGIF2 TGFB induced factor homeobox 2 1 1
MIRT053747 SERPINH1 serpin family H member 1 2 2
MIRT053748 NOTCH2 notch 2 4 1
MIRT053749 PPARD peroxisome proliferator activated receptor delta 1 1
MIRT054045 SNAI3 snail family transcriptional repressor 3 2 1
MIRT054192 AKT2 AKT serine/threonine kinase 2 4 2
MIRT054574 PER1 period circadian clock 1 3 1
MIRT060983 LAMC1 laminin subunit gamma 1 3 1
MIRT061662 BTG2 BTG anti-proliferation factor 2 2 4
MIRT067385 TMTC3 transmembrane and tetratricopeptide repeat containing 3 2 4
MIRT079942 RNF138 ring finger protein 138 2 2
MIRT080798 SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 2 4
MIRT081893 KCTD15 potassium channel tetramerization domain containing 15 2 8
MIRT082515 CALM3 calmodulin 3 2 2
MIRT085293 CCNT2 cyclin T2 2 6
MIRT102856 INSIG1 insulin induced gene 1 2 2
MIRT207249 TET3 tet methylcytosine dioxygenase 3 2 2
MIRT207755 VHL von Hippel-Lindau tumor suppressor 2 4
MIRT210969 TET2 tet methylcytosine dioxygenase 2 1 1
MIRT211650 ABCE1 ATP binding cassette subfamily E member 1 2 2
MIRT213230 REST RE1 silencing transcription factor 2 10
MIRT225103 GOLGA7 golgin A7 2 2
MIRT250481 MAZ MYC associated zinc finger protein 2 2
MIRT264266 FAM102B family with sequence similarity 102 member B 2 2
MIRT267090 ZFP91 ZFP91 zinc finger protein 2 2
MIRT303363 MXD1 MAX dimerization protein 1 2 1
MIRT316344 ULBP2 UL16 binding protein 2 2 2
MIRT401476 AIM1 crystallin beta-gamma domain containing 1 2 1
MIRT437369 LAMC2 laminin subunit gamma 2 3 1
MIRT437372 ITGA6 integrin subunit alpha 6 3 2
MIRT437552 COL5A2 collagen type V alpha 2 chain 1 1
MIRT437553 COL10A1 collagen type X alpha 1 chain 1 1
MIRT437554 SPARC secreted protein acidic and cysteine rich 1 1
MIRT437555 FBN1 fibrillin 1 1 1
MIRT437556 LOX lysyl oxidase 2 2
MIRT437557 PDGFRB platelet derived growth factor receptor beta 2 2
MIRT437710 PHACTR2 phosphatase and actin regulator 2 2 1
MIRT437713 TUBB2A tubulin beta 2A class IIa 2 1
MIRT437716 EMP1 epithelial membrane protein 1 2 1
MIRT437719 SNX24 sorting nexin 24 2 1
MIRT437722 AMFR autocrine motility factor receptor 2 1
MIRT437725 RIOK3 RIO kinase 3 2 1
MIRT437728 WDR26 WD repeat domain 26 4 3
MIRT437731 DSC2 desmocollin 2 2 1
MIRT437870 IL32 interleukin 32 1 1
MIRT438911 GATA3 GATA binding protein 3 2 1
MIRT438912 PDGFRA platelet derived growth factor receptor alpha 2 1
MIRT438913 PDGFC platelet derived growth factor C 2 1
MIRT438914 PDGFB platelet derived growth factor subunit B 2 1
MIRT438915 PDGFA platelet derived growth factor subunit A 2 1
MIRT438916 MMP9 matrix metallopeptidase 9 2 1
MIRT438917 LOXL4 lysyl oxidase like 4 2 1
MIRT438918 LOXL2 lysyl oxidase like 2 2 1
MIRT438919 ITGB1 integrin subunit beta 1 2 1
MIRT438920 ANGPTL4 angiopoietin like 4 2 1
MIRT454812 NEDD9 neural precursor cell expressed, developmentally down-regulated 9 2 2
MIRT456827 MORF4L2 mortality factor 4 like 2 2 8
MIRT462151 RPL22 ribosomal protein L22 2 2
MIRT465314 TRAM2 translocation associated membrane protein 2 2 2
MIRT467808 SLC2A14 solute carrier family 2 member 14 2 2
MIRT467829 SLC29A2 solute carrier family 29 member 2 2 2
MIRT467971 SLC16A1 solute carrier family 16 member 1 2 4
MIRT468225 SGK1 serum/glucocorticoid regulated kinase 1 2 2
MIRT469448 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT469723 RAB40C RAB40C, member RAS oncogene family 2 2
MIRT469841 R3HDM4 R3H domain containing 4 2 2
MIRT472643 NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit 2 2
MIRT474209 LEPRE1 prolyl 3-hydroxylase 1 1 1
MIRT474576 KLHDC3 kelch domain containing 3 2 2
MIRT475837 HDGF heparin binding growth factor 2 4
MIRT476721 FRK fyn related Src family tyrosine kinase 2 4
MIRT477473 ELMSAN1 ELM2 and Myb/SANT domain containing 1 2 2
MIRT478668 CTC1 CST telomere replication complex component 1 2 14
MIRT478710 CSRNP2 cysteine and serine rich nuclear protein 2 2 2
MIRT478985 COMMD2 COMM domain containing 2 2 2
MIRT479826 CCNA2 cyclin A2 2 8
MIRT479901 CCDC117 coiled-coil domain containing 117 2 2
MIRT480066 CAND1 cullin associated and neddylation dissociated 1 2 2
MIRT482012 AMER1 APC membrane recruitment protein 1 2 8
MIRT489024 C1QTNF6 C1q and TNF related 6 5 2
MIRT492513 RAET1L retinoic acid early transcript 1L 2 2
MIRT493825 FSCN1 fascin actin-bundling protein 1 2 2
MIRT495936 SLC7A5P2 solute carrier family 7 member 5 pseudogene 2 2 2
MIRT496358 PPY pancreatic polypeptide 2 2
MIRT496662 TMEM237 transmembrane protein 237 2 2
MIRT497644 GLDN gliomedin 2 2
MIRT501878 MORF4L1 mortality factor 4 like 1 2 8
MIRT502932 CDC42SE1 CDC42 small effector 1 2 4
MIRT506750 LDOC1L retrotransposon Gag like 6 2 6
MIRT507168 GAS2L3 growth arrest specific 2 like 3 2 2
MIRT514918 MDM2 MDM2 proto-oncogene 2 6
MIRT523962 DYNLT1 dynein light chain Tctex-type 1 2 4
MIRT527675 CASP8 caspase 8 2 2
MIRT536936 HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 2 2
MIRT537359 FJX1 four jointed box 1 2 2
MIRT537687 ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 2 2
MIRT538124 DDX6 DEAD-box helicase 6 2 2
MIRT538813 C21orf91 chromosome 21 open reading frame 91 2 2
MIRT546938 PTP4A1 protein tyrosine phosphatase type IVA, member 1 2 2
MIRT547104 PLAG1 PLAG1 zinc finger 2 2
MIRT547823 ISG20L2 interferon stimulated exonuclease gene 20 like 2 2 2
MIRT548237 FEM1B fem-1 homolog B 2 2
MIRT550036 WWTR1 WW domain containing transcription regulator 1 2 2
MIRT552619 ZBTB5 zinc finger and BTB domain containing 5 2 2
MIRT556562 LIMS1 LIM zinc finger domain containing 1 2 2
MIRT558857 CDC23 cell division cycle 23 2 2
MIRT565485 SPRTN SprT-like N-terminal domain 2 2
MIRT568205 CBX6 chromobox 6 2 2
MIRT576774 Tmem127 transmembrane protein 127 2 2
MIRT576958 Pigs phosphatidylinositol glycan anchor biosynthesis, class S 2 3
MIRT610003 PIGS phosphatidylinositol glycan anchor biosynthesis class S 2 3
MIRT616511 COX7A2L cytochrome c oxidase subunit 7A2 like 2 2
MIRT640887 ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2 2
MIRT641350 RAB11FIP1 RAB11 family interacting protein 1 2 2
MIRT642978 TESPA1 thymocyte expressed, positive selection associated 1 2 2
MIRT643634 YY2 YY2 transcription factor 2 2
MIRT644386 ZNF286A zinc finger protein 286A 2 2
MIRT650749 YAE1D1 Yae1 domain containing 1 2 2
MIRT661585 EPHX2 epoxide hydrolase 2 2 2
MIRT664287 RNMTL1 mitochondrial rRNA methyltransferase 3 2 2
MIRT689393 ZNF850 zinc finger protein 850 2 2
MIRT693815 SEC31A SEC31 homolog A, COPII coat complex component 2 2
MIRT694532 TRIM72 tripartite motif containing 72 2 2
MIRT694628 ZFPM1 zinc finger protein, FOG family member 1 2 2
MIRT695135 PRY2 PTPN13-like, Y-linked 2 2 2
MIRT695152 PRY PTPN13-like, Y-linked 2 2
MIRT703640 FBRS fibrosin 2 2
MIRT704551 CNBP CCHC-type zinc finger nucleic acid binding protein 2 2
MIRT704967 CBX2 chromobox 2 2 2
MIRT705497 ASXL2 additional sex combs like 2, transcriptional regulator 2 2
MIRT707993 OTUD4 OTU deubiquitinase 4 2 2
MIRT708741 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT710621 COLEC10 collectin subfamily member 10 2 2
MIRT713056 IFRD1 interferon related developmental regulator 1 2 2
MIRT715515 MAPKBP1 mitogen-activated protein kinase binding protein 1 2 2
MIRT720770 FAM193A family with sequence similarity 193 member A 2 2
MIRT731925 AQP4 aquaporin 4 3 1
MIRT732673 HMGB1 high mobility group box 1 3 0
MIRT734350 IL6 interleukin 6 1 0
MIRT734351 TP53 tumor protein p53 1 0
MIRT734565 BCL2L11 BCL2 like 11 2 0
MIRT734770 TRIM44 tripartite motif containing 44 2 0
MIRT734771 CCNE1 cyclin E1 2 0
MIRT735260 STAT3 signal transducer and activator of transcription 3 6 1
MIRT735414 HBP1 HMG-box transcription factor 1 3 0
MIRT735537 HIF3A hypoxia inducible factor 3 alpha subunit 3 0
MIRT735639 HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 3 0
MIRT735641 AKT3 AKT serine/threonine kinase 3 3 0
MIRT735943 DNM3OS DNM3 opposite strand/antisense RNA 4 0
MIRT737493 SMAD3 SMAD family member 3 1 0
MIRT737577 SNAI1 snail family transcriptional repressor 1 2 0
MIRT755941 SLMAP sarcolemma associated protein 4 1
MIRT755963 ROBO1 roundabout guidance receptor 1 5 1
MIRT755964 SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 5 1
MIRT756271 YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon 3 1
MIRT756364 LIN7A lin-7 homolog A, crumbs cell polarity complex component 2 1
MIRT756474 COL5A1 collagen type V alpha 1 chain 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-29b 5-aza-2'-deoxycytidine (5-Aza-CdR) approved 451668 Microarray Pancreatic Cancer MiaPACA-2 cells 19407485 2009 up-regulated
miR-29b 5-aza-2'-deoxycytidine (5-Aza-CdR) approved 451668 Microarray Pancreatic Cancer PANC-1 cells 19407485 2009 up-regulated
miR-29b 5-aza-2'-deoxycytidine (5-Aza-CdR) + trichostatin A(TSA) NULL NULL Microarray Pancreatic Cancer MiaPACA-2 cells 19407485 2009 up-regulated
miR-29b 5-aza-2'-deoxycytidine (5-Aza-CdR) + trichostatin A(TSA) NULL NULL Microarray Pancreatic Cancer PANC-1 cells 19407485 2009 up-regulated
miR-29b Trichostatin A (TSA) NULL 444732 Microarray Pancreatic Cancer MiaPACA-2 cells 19407485 2009 up-regulated
miR-29b Trichostatin A (TSA) NULL 444732 Microarray Pancreatic Cancer PANC-1 cells 19407485 2009 up-regulated
miR-29b Glucose NULL 5793 Microarray proximal tubule cell line HK-2 20067797 2010 down-regulated
miR-29b Dihydrotestosterone(DHT) NULL 10635 Microarray prostate cancer 20945501 2011 up-regulated
miR-29b Dihydrotestosterone(DHT) NULL 10635 Quantitative real-time PCR prostate cancer 20945501 2011 up-regulated
miR-29b Formaldehyde NULL 712 Microarray Human lung epithelial cells (A549) 21147603 2011 down-regulated
miR-29b Enoxacin approved 3229 Quantitative real-time PCR HCT-116 and RKO colon cancer cell lines 21368194 2011 up-regulated
miR-29b Ginsenoside Rh2 NULL 119307 Microarray human glioma cells U251 21372826 2011 up-regulated
miR-29b Testosterone + 1,25-Dihydroxyvitamin D3 approved NULL Microarray prostate cancer 21592394 2011 up-regulated
miR-29b Progesterone approved 5994 Microarray Breast cancer 22330642 2012 down-regulated
miR-29b Progesterone approved 5994 Quantitative real-time PCR Breast cancer 22330642 2012 down-regulated
miR-29b Trastuzumab approved NULL Microarray SKBR3 cells. 22384020 2012 up-regulated
miR-29b Glucocorticoid NULL NULL Quantitative real-time PCR Eosinophilic esophagitis 22815788 2012 up-regulated
miR-29b Glucocorticoid NULL NULL TaqMan low-density array Eosinophilic esophagitis 22815788 2012 up-regulated
miR-29b CCl4 NULL 5943 Quantitative real-time PCR liver 22393047 2012 down-regulated
miR-29b Estrogen NULL NULL Quantitative real-time PCR liver 22393047 2012 up-regulated
miR-29b Galactose NULL 6036 Quantitative real-time PCR lens 22736950 2012 down-regulated
miR-29b 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR) NULL 16078949 Microarray hepatocytes 23107762 2013 down-regulated
miR-29b Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 up-regulated
miR-29b Phenethyl isothiocyanate(PEITC) NULL 16741 Microarray neonatal mice liver 20145010 2010 down-regulated
miR-29b Benzo(a)pyrene NULL 2336 Microarray Adult male B6C3F1 mice 21569818 2011 up-regulated
miR-29b Cocaine NULL 446220 Next-generation sequencing ventral striatum 21708909 2011 down-regulated
miR-29b Urethane NULL 5641 Quantitative real-time PCR mouse lung 24361357 2014 down-regulated
miR-29b Ethanol NULL 702 Quantitative real-time PCR Cerebellar Granule Neurons cells 24554719 2014 down-regulated
miR-29b Rapamycin approved 5284616 Quantitative real-time PCR HL-1 cells 25062042 2014 up-regualted
miR-29b Estradiol benzoate (EB) NULL NULL Quantitative real-time PCR adult germ cell 22334722 2012 up-regulated
miR-29b Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 up-regulated
miR-29b-3p Docosahexaenoic acid NULL 445580 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-29b Sorafenib 216239 NSC747971 approved resistant High Hepatocellular Carcinoma cell line (HepG2, SK-HEP-1)
hsa-miR-29b-3p (1S,10R,12R,14R,15S)-15-hydroxyspiro[13,16-dioxapentacyclo[8.5.1.01,10.03,8.012,14]hexadeca-3,5,7-triene-11,3'-2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene]-2,9-dione 388424 NSC683332 resistant
hsa-miR-29b-3p (5Z)-5-[(4-oxothieno[2,3-b]thiochromen-2-yl)methylidene]-2-sulfanylideneimidazolidin-4-one 5468927 NSC679240 resistant
hsa-miR-29b-3p (6aS)-3-[5-[4-(2-diethoxyphosphorylethyl)piperazin-1-yl]pentoxy]-2-methoxy-6a,7,8,9-tetrahydropyrrolo[2,1-c][1,4]benzodiazepin-11-one 25113728 NSC744025 resistant
hsa-miR-29b-3p 1-adamantylmethyl 4-[(2,5-dihydroxyphenyl)methylamino]benzoate 391131 NSC689857 resistant
hsa-miR-29b-3p 2-((5-methyl-3-isoxazolyl)amino)-4-((5-methyl-3-isoxazolyl)imino)-1(4h)-naphthalenone 373420 NSC649750 sensitive
hsa-miR-29b-3p 2-(1-adamantyl)ethyl 4-[(2,5-dihydroxyphenyl)methylamino]benzoate 403758 NSC719177 resistant
hsa-miR-29b-3p 2-(3-(2-methoxy-4-(4-methylene-5-oxotetrahydro-2-furanyl)phenoxy)propyl)-1h-isoindole-1,3(2h)-dione 381521 NSC668277 resistant
hsa-miR-29b-3p 2-[(dimethylamino)methyl]-3-[(Z)-heptadec-10-enyl]-5-methoxybenzene-1,4-diol;hydrochloride 5387959 NSC630004 resistant
hsa-miR-29b-3p 2-[[(E)-3-(2-chlorophenyl)prop-2-enoyl]amino]-5-iodobenzamide 53329762 NSC748148 resistant
hsa-miR-29b-3p 2-acetylimidazo[4,5-b]pyridin 4 tolyl 3 thiosemicarbazone 135440014 NSC674106 resistant
hsa-miR-29b-3p 2-amino-1-N,9-N-bis[10-[(4-hydroxyphenyl)methyl]-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3-propan-2-yl-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]-4,6-dimethyl-3-oxophenoxazine-1,9-dicarboxamide 16129921 NSC684901 resistant
hsa-miR-29b-3p 2-amino-1-N,9-N-bis[10-[(4-methoxyphenyl)methyl]-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3-propan-2-yl-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]-4,6-dimethyl-3-oxophenoxazine-1,9-dicarboxamide 16129907 NSC684908 resistant
hsa-miR-29b-3p 2-amino-9-chloro-3,5-bis(4-chlorophenyl)pyrimido[4,5-c]quinolin-1-one 16126264 NSC741296 resistant
hsa-miR-29b-3p 2,3-bis(4,5-dimethyl-3,6-dioxo-cyclohexa-1,4-dien-1-yl)-5,6-dimethyl-1,4-benzoquinone 394545 NSC698090 sensitive
hsa-miR-29b-3p 3-(4-chlorophenyl)-5-methyl-[1,2]oxazolo[5,4-d]triazin-4-one 399226 NSC709900 resistant
hsa-miR-29b-3p 4-[4-[2,3-bis(hydroxymethyl)pyrrol-1-yl]butanoylamino]-n-[5-[[5-[3-(dimethylamino)propylcarbamoyl]-1-methylpyrrol-3-yl]carbamoyl]-1-methylpyrrol-3-yl]-1-methylpyrrole-2-carboxamide 384021 NSC673131 resistant
hsa-miR-29b-3p 5-(4-methoxyphenyl)-3-(3,4,5-trimethoxyphenyl)-4,5-dihydro-1h-pyrazole 49865894 NSC748404 resistant
hsa-miR-29b-3p 5,11-dimethyl-1h-benzo[a]carbazole-1,4(11h)-dione 372651 NSC648148 resistant
hsa-miR-29b-3p Acetic acid;3-[4-(2-hydroxyethyl)piperidin-1-yl]-N-[6-[3-[4-(2-hydroxyethyl)piperidin-1-yl]propanoylamino]-9,10-dioxoanthracen-2-yl]propanamide 374314 NSC651841 resistant
hsa-miR-29b-3p Beacon red 135421797 NSC12455 resistant
hsa-miR-29b-3p Benzoic acid, 3,4,5-trihydroxy-, phenyl ester 333279 NSC333571 resistant
hsa-miR-29b-3p Csa13 24205348 NSC735211 sensitive
hsa-miR-29b-3p Mefloquine hydrochloride 456309 NSC157387 sensitive
hsa-miR-29b-3p Methyl 3-hydroxy-3-[(15R)-15-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyl]propanedithioate 383730 NSC672159 resistant
hsa-miR-29b-3p Methyl 6-[[(3S,4aR,6aR,6bS,8R,8aR,12aS,14aR,14bR)-8a-[3-[3,4-dihydroxy-6-methyl-5-(3,4,5-trihydroxyoxan-2-yl)oxyoxan-2-yl]oxy-4,5-dihydroxyoxan-2-yl]oxycarbonyl-8-hydroxy-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropi 385532 NSC676788 sensitive
hsa-miR-29b-3p Naphth[2,3-d]oxazol-9-one, 2-methyl-4-(phenylimino)- 160386 NSC650573 sensitive
hsa-miR-29b-3p NSC148077 NSC148077 resistant
hsa-miR-29b-3p NSC175490 NSC175490 resistant
hsa-miR-29b-3p NSC175493 NSC175493 resistant
hsa-miR-29b-3p NSC85701 NSC85701 resistant
hsa-miR-29b-3p Oxin 1923 NSC2039 approved resistant
hsa-miR-29b-3p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-29b-3p Etoposide 36462 NSC141540 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-29b-3p Cisplatin 5460033 NSC119875 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-29b-3p Paclitaxel 36314 NSC125973 approved resistant High Breast Cancer cell line (MDA-435)
hsa-miR-29b-3p Paclitaxel 36314 NSC125973 approved sensitive High Breast Cancer cell line (MDA-MB-435, MDA-MB-436, SKBr3, BT-474, MDA-MB-231, MCF7)
hsa-miR-29b-3p Imatinib 5291 NSC743414 approved resistant High Myelogenous Leukemia cell line (MYL)
hsa-miR-29b-3p Tamoxifen 2733525 NSC180973 approved sensitive High Breast Cancer cell line (MCF-7, LY2)
hsa-miR-29b-3p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (SKOV3)
hsa-miR-29b-3p Cyclopamine 442972 NSC734950 resistant Low Prostate Cancer cell line (DU-145, PC-3)
hsa-miR-29b-3p Paclitaxel 36314 NSC125973 approved resistant Low Prostate Cancer cell line (DU-145, PC-3)
hsa-miR-29b-3p Etoposide 36462 NSC141540 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-29b-3p Decitabine 451668 approved sensitive Low Acute Myeloid Leukemia tissue and cell line (Kasumi-1, NB4, FDC-P1-KITmut)
hsa-miR-29b-3p Gemcitabine 60750 NSC613327 approved resistant High Bladder Cancer cell line (RT4, J82,TCCSUP, UM-UC-3,RT112,CUBIII)
hsa-miR-29b-3p Oxaliplatin 6857599 NSC266046 approved resistant High Colorectal Cancer cell line (RKO)
hsa-miR-29b-3p Gemcitabine 60750 NSC613327 approved sensitive Low Cholangiocarcinoma cell line (HuCCT1, HuH28)
hsa-miR-29b-3p Fluorouracil + Oxaliplatin resistant High Colorectal Cancer tissue
hsa-miR-29b-3p Ethanol 702 NSC85228 approved resistant Low Cerebellum Granule Neuron tissue
hsa-miR-29b-3p Chemotherapy sensitive Low Ovarian Cancer tissue
hsa-miR-29b-3p Paclitaxel 36314 NSC125973 approved sensitive Low Ovarian Cancer cell line (ES2, AMOC2)
hsa-miR-29b-3p Fluorouracil 3385 NSC19893 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-miR-29b-3p Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-miR-29b-3p Bortezomib 387447 NSC681239 approved sensitive Low Melanoma cell line (RPMI8226)
hsa-miR-29b-3p Carfilzomib 11556711 NSC756640 approved sensitive Low Melanoma cell line (RPMI8226)
hsa-miR-29b-3p Ixazomib 25183872 approved sensitive Low Melanoma cell line (RPMI8226)
hsa-miR-29b-3p Interferon-Gamma sensitive Low Colorectal Cancer cell line (HCT-116, HT-29, LS174T, SW480,SW620, HEK293)
hsa-miR-29b-3p Taxane 9548828 sensitive High Prostate Cancer cell line (PC-3, PR200)
hsa-miR-29b-3p Taxane 9548828 sensitive High Prostate Cancer cell line (PC-3, PR70)
hsa-miR-29b-3p Tamoxifen 2733525 NSC180973 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-29b-3p Platinum 23939 resistant Low Ovarian Cancer tissue
hsa-miR-29b-3p Sorafenib 216239 NSC747971 approved resistant High Hepatocellular Carcinoma cell line (Huh-7, PLC)
hsa-miR-29b-3p Imatinib 5291 NSC743414 approved resistant High Gastrointestinal Stromal Tumor cell line (882R-NC, 882R-OE, 882R-KD)
hsa-miR-29b-3p Cisplatin 5460033 NSC119875 approved sensitive Low Non-Small Cell Lung Cancer cell line (A549, H1299)
hsa-miR-29b-3p Cisplatin 5460033 NSC119875 approved sensitive High Gallbladder Cancer cell line (GBC-SD, NOZ)
hsa-miR-29b-3p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-29b-3p Dabrafenib 44462760 NSC764134 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-29b-3p Curcumin 969516 NSC32982 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-29b-3p Doxorubicin 31703 NSC123127 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-29b-3p Paclitaxel 36314 NSC125973 approved sensitive Low Breast Cancer cell line (MCF-7)
hsa-miR-29b-3p Gemcitabine 60750 NSC613327 approved resistant High Cholangiocarcinoma cell line (CCLP-1, MzChA-1)
hsa-miR-29b-3p Oxaliplatin 6857599 NSC266046 approved sensitive Low Colorectal Cancer cell line (SW480)
hsa-miR-29b-3p Paclitaxel 36314 NSC125973 approved sensitive Low Prostate Cancer cell line (PC-3-R)
hsa-miR-29b-3p Methotrexate 126941 NSC740 approved sensitive Low Osteosarcoma tissue and cell line (MG-63, U-2-OS)
hsa-miR-29b-3p Crizotinib 11626560 NSC749005 approved resistant High Non-Small Cell Lung Cancer cell line (NCI-H2228, DFCI032)
hsa-miR-29b-3p Lorlatinib 71731823 NSC780108 approved resistant High Non-Small Cell Lung Cancer cell line (NCI-H2228, DFCI032)
hsa-miR-29b-3p Doxorubicin 31703 NSC123127 approved sensitive Low Osteosarcoma cell line (MG-63)
hsa-miR-29b-3p Gemcitabine 60750 NSC613327 approved sensitive Low Pancreatic Cancer cell line (PANC-1 cell, BXPC-3)
hsa-miR-29b-3p Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7, MCF-7-21)
hsa-miR-29b-3p Cisplatin 5460033 NSC119875 approved sensitive Low Endometrial Cancer cell line (HEC-1-B)
hsa-miR-29b-3p Fluorouracil 3385 NSC19893 approved sensitive High Colorectal Cancer cell line (HT-29)
hsa-miR-29b-3p Oxaliplatin 6857599 NSC266046 approved sensitive Low Colon Cancer cell line (SW480, SW620)
hsa-miR-29b-3p Temozolomide 5394 NSC362856 approved sensitive Low Glioma cell line (LN229, U87MG, U251)
hsa-miR-29b-3p Temozolomide 5394 NSC362856 approved sensitive Low Glioblastoma cell line (U251, U87MG)
hsa-miR-29b-3p Cisplatin 5460033 NSC119875 approved sensitive Low Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-29b-3p Oxaliplatin 6857599 NSC266046 approved sensitive Low Colorectal Cancer cell line (HT-29, DLD1)
hsa-miR-29b-3p Bortezomib 387447 NSC681239 approved resistant Low Multiple Myeloma tissue
hsa-miR-29b-3p Palbociclib 5330286 NSC758247 approved sensitive High Breast Cancer cell line (MDA-MB-231, Hs578t, SKBR3, MCF-7)
hsa-miR-29b-3p Temozolomide 5394 NSC362856 approved sensitive Low Glioma tissue
hsa-miR-29b-3p Cisplatin 5460033 NSC119875 approved sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-29b-3p Fluorouracil 3385 NSC19893 approved resistant Low Colorectal Cancer cell line (HT-29, HCT-116, SW480, SW620, LoVo, SW48, DLD-1, Caco-1, HCT-15)
hsa-miR-29b-3p Sorafenib 216239 NSC747971 approved resistant High Hepatocellular Carcinoma cell line (Huh-7, PLC)
hsa-miR-29b-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-29b-3p Cisplatin 5460033 NSC119875 approved resistant cell line (CAL-27) (mitochondrial RNA)
hsa-miR-29b-3p Cisplatin 5460033 NSC119875 approved resistant cell line (CAL-27) (cytosolic RNA)
hsa-miR-29b-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-miR-29b-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-29b-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (SKVO3ip1)
hsa-miR-29b-3p Paclitaxel 36314 NSC125973 approved resistant cell line (HeyA8)
hsa-miR-29b-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM17)
hsa-miR-29b-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM16)
hsa-miR-29b-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (BAS)
hsa-miR-29b-3p Doxorubicin 31703 NSC123127 approved sensitive cell line (BAS)
hsa-miR-29b-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-29b-3p Exemestane 60198 NSC713563 approved resistant cell line (MCF-7)
hsa-miR-29b-3p Testosterone 6013 NSC9700 approved resistant cell line (MCF-7)
hsa-miR-29b-3p Testosterone+Anastrozole resistant cell line (MCF-7)
hsa-miR-29b-3p Testosterone+Letrozole resistant cell line (MCF-7)
hsa-miR-29b-3p Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-29b-3p Cisplatin 5460033 NSC119875 approved resistant cell line (MGC-803)
hsa-miR-29b-3p 4-Hydroxytamoxifen+Tamoxifen resistant cell line (LY2)
hsa-miR-29b-3p Ethanol+Tamoxifen resistant cell line (LY2)
hsa-miR-29b-3p Paclitaxel 36314 NSC125973 approved resistant cell line (SKOV3)
hsa-miR-29b-3p Pegylated interferon alpha+Ribavirin sensitive tissue (chronic hepatitis C)
hsa-miR-29b-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (HuH28)
hsa-miR-29b-3p Platinum 23939 resistant tissue (non-small cell lung cancer)
hsa-miR-29b-3p Tamoxifen 2733525 NSC180973 approved sensitive cell line (TamR4)
hsa-miR-29b-3p Oxaliplatin 6857599 NSC266046 approved sensitive cell line (IGROV-1)
hsa-miR-29b-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (IGROV-1)
hsa-miR-29b-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (PC3PR200)
hsa-miR-29b-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (PC3PR70)
hsa-miR-29b-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-29b-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM16)
hsa-miR-29b-3p Bortezomib 387447 NSC681239 approved resistant cell line (CCRF-CEM) (100 nM)
hsa-miR-29b-3p Bortezomib 387447 NSC681239 approved sensitive cell line (CCRF-CEM) (200 nM)
hsa-miR-29b-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-29b-3p Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)
hsa-miR-29b-3p Cisplatin 5460033 NSC119875 approved resistant cell line (OVCAR3)
hsa-miR-29b-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (H23)
hsa-miR-29b-3p Cetuximab sensitive tissue (colorectal carcinoma)

Error report submission