miRTarBase - #MIRT004443


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pre-miRNA Information
pre-miRNA hsa-mir-383   
Genomic Coordinates chr8: 14853438 - 14853510
Synonyms MIRN383, hsa-mir-383, MIR383
Description Homo sapiens miR-383 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-383-5p
Sequence 7| AGAUCAGAAGGUGAUUGUGGCU |28
Evidence Experimental
Experiments Cloned
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN26994512 7 COSMIC
COSN30109318 22 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs112302475 1 dbSNP
rs756858316 1 dbSNP
rs757040124 3 dbSNP
rs1419085595 4 dbSNP
rs912771170 5 dbSNP
rs1190491141 6 dbSNP
rs986831934 7 dbSNP
rs1471946963 9 dbSNP
rs1237080909 10 dbSNP
rs757526216 11 dbSNP
rs1431645579 13 dbSNP
rs763747200 13 dbSNP
rs184836993 15 dbSNP
rs913343525 17 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol VEGFA   
Synonyms MVCD1, VEGF, VPF
Description vascular endothelial growth factor A
Transcript NM_001025369   
Other Transcripts NM_001025367 , NM_001025368 , NM_001025366 , NM_001025370 , NM_001033756 , NM_001171622 , NM_001171623 , NM_001171624 , NM_001171625 , NM_001171626 , NM_001171627 , NM_001171628 , NM_001171629 , NM_001171630 , NM_003376   
Expression
Putative miRNA Targets on VEGFA
3'UTR of VEGFA
(miRNA target sites are highlighted)		 
>VEGFA|NM_001025369|3'UTR
   1 CAAGCCGAGGCGGTGAGCCGGGCAGGAGGAAGGAGCCTCCCTCAGGGTTTCGGGAACCAGATCTCTCACCAGGAAAGACT
  81 GATACAGAACGATCGATACAGAAACCACGCTGCCGCCACCACACCATCACCATCGACAGAACAGTCCTTAATCCAGAAAC
 161 CTGAAATGAAGGAAGAGGAGACTCTGCGCAGAGCACTTTGGGTCCGGAGGGCGAGACTCCGGCGGAAGCATTCCCGGGCG
 241 GGTGACCCAGCACGGTCCCTCTTGGAATTGGATTCGCCATTTTATTTTTCTTGCTGCTAAATCACCGAGCCCGGAAGATT
 321 AGAGAGTTTTATTTCTGGGATTCCTGTAGACACACCCACCCACATACATACATTTATATATATATATATTATATATATAT
 401 AAAAATAAATATCTCTATTTTATATATATAAAATATATATATTCTTTTTTTAAATTAACAGTGCTAATGTTATTGGTGTC
 481 TTCACTGGATGTATTTGACTGCTGTGGACTTGAGTTGGGAGGGGAATGTTCCCACTCAGATCCTGACAGGGAAGAGGAGG
 561 AGATGAGAGACTCTGGCATGATCTTTTTTTTGTCCCACTTGGTGGGGCCAGGGTCCTCTCCCCTGCCCAGGAATGTGCAA
 641 GGCCAGGGCATGGGGGCAAATATGACCCAGTTTTGGGAACACCGACAAACCCAGCCCTGGCGCTGAGCCTCTCTACCCCA
 721 GGTCAGACGGACAGAAAGACAGATCACAGGTACAGGGATGAGGACACCGGCTCTGACCAGGAGTTTGGGGAGCTTCAGGA
 801 CATTGCTGTGCTTTGGGGATTCCCTCCACATGCTGCACGCGCATCTCGCCCCCAGGGGCACTGCCTGGAAGATTCAGGAG
 881 CCTGGGCGGCCTTCGCTTACTCTCACCTGCTTCTGAGTTGCCCAGGAGACCACTGGCAGATGTCCCGGCGAAGAGAAGAG
 961 ACACATTGTTGGAAGAAGCAGCCCATGACAGCTCCCCTTCCTGGGACTCGCCCTCATCCTCTTCCTGCTCCCCTTCCTGG
1041 GGTGCAGCCTAAAAGGACCTATGTCCTCACACCATTGAAACCACTAGTTCTGTCCCCCCAGGAGACCTGGTTGTGTGTGT
1121 GTGAGTGGTTGACCTTCCTCCATCCCCTGGTCCTTCCCTTCCCTTCCCGAGGCACAGAGAGACAGGGCAGGATCCACGTG
1201 CCCATTGTGGAGGCAGAGAAAAGAGAAAGTGTTTTATATACGGTACTTATTTAATATCCCTTTTTAATTAGAAATTAAAA
1281 CAGTTAATTTAATTAAAGAGTAGGGTTTTTTTTCAGTATTCTTGGTTAATATTTAATTTCAACTATTTATGAGATGTATC
1361 TTTTGCTCTCTCTTGCTCTCTTATTTGTACCGGTTTTTGTATATAAAATTCATGTTTCCAATCTCTCTCTCCCTGATCGG
1441 TGACAGTCACTAGCTTATCTTGAACAGATATTTAATTTTGCTAACACTCAGCTCTGCCCTCCCCGATCCCCTGGCTCCCC
1521 AGCACACATTCCTTTGAAATAAGGTTTCAATATACATCTACATACTATATATATATTTGGCAACTTGTATTTGTGTGTAT
1601 ATATATATATATATGTTTATGTATATATGTGATTCTGATAAAATAGACATTGCTATTCTGTTTTTTATATGTAAAAACAA
1681 AACAAGAAAAAATAGAGAATTCTACATACTAAATCTCTCTCCTTTTTTAATTTTAATATTTGTTATCATTTATTTATTGG
1761 TGCTACTGTTTATCCGTAATAATTGTGGGGAAAAGATATTAACATCACGTCTTTGTCTCTAGTGCAGTTTTTCGAGATAT
1841 TCCGTAGTACATATTTATTTTTAAACAACGACAAAGAAATACAGATATATCTTAAAAAAAAAAAAGCATTTTGTATTAAA
1921 GAATTTAATTCTGATCTCAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ucggUGUUAGUGGAAGACUAGa 5'
              | |||:   |||||||| 
Target 5' ttaaAGAATTTAATTCTGATCt 3'
 1916 - 1937 154.00 -11.90
2 
miRNA  3' ucgGUGU-UAGUGGAAGACUAga 5'
             :|:| ||    |||||||  
Target 5' atgTATATATGTGATTCTGATaa 3'
 1619 - 1641 127.00 -7.20
3 
miRNA  3' ucgguGUUAGUG---GA-AGACUAGa 5'
               ||||| |   ||  |||||| 
Target 5' gtttcCAATCTCTCTCTCCCTGATCg 3'
 1414 - 1439 125.00 -11.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM6846710 7 COSMIC
COSM6819794 11 COSMIC
COSM7497899 13 COSMIC
COSM7701081 13 COSMIC
COSM3627761 14 COSMIC
COSM7659088 16 COSMIC
COSN26958505 21 COSMIC
COSN30524014 29 COSMIC
COSN27004587 41 COSMIC
COSM9012089 52 COSMIC
COSM3352182 64 COSMIC
COSM3411133 77 COSMIC
COSM7974398 79 COSMIC
COSN30143001 88 COSMIC
COSN30102404 95 COSMIC
COSN31508134 96 COSMIC
COSN31596624 99 COSMIC
COSN30455964 114 COSMIC
COSN4893933 129 COSMIC
COSN30153771 136 COSMIC
COSN30476233 148 COSMIC
COSN30456378 154 COSMIC
COSN30133882 169 COSMIC
COSN30171185 169 COSMIC
COSN30584487 207 COSMIC
COSN31567017 221 COSMIC
COSN30158763 245 COSMIC
COSN167777 254 COSMIC
COSN30632779 277 COSMIC
COSN31485413 294 COSMIC
COSN31564704 314 COSMIC
COSN30541187 426 COSMIC
COSN31593685 466 COSMIC
COSN31522262 489 COSMIC
COSN31594835 539 COSMIC
COSN20274509 584 COSMIC
COSN21290319 729 COSMIC
COSN28703738 769 COSMIC
COSN30164957 927 COSMIC
COSN31545074 950 COSMIC
COSN2162691 1024 COSMIC
COSN24614414 1129 COSMIC
COSN31533515 1166 COSMIC
COSN31524418 1170 COSMIC
COSN31563310 1188 COSMIC
COSN28249886 1314 COSMIC
COSN31606167 1314 COSMIC
COSN7883560 1375 COSMIC
COSN8514383 1428 COSMIC
COSN31548668 1559 COSMIC
COSN28017862 1576 COSMIC
COSN7883561 1598 COSMIC
COSN23225630 1614 COSMIC
COSN31486284 1638 COSMIC
COSN31530820 1667 COSMIC
COSN31480000 1720 COSMIC
COSN31610033 1741 COSMIC
COSN31516478 1759 COSMIC
COSN30175512 1810 COSMIC
COSN19503017 1819 COSMIC
COSN20213960 1825 COSMIC
COSN31522645 1827 COSMIC
COSN31551365 1870 COSMIC
COSN27224860 1906 COSMIC
COSN31568751 1922 COSMIC
rs3025053 1043 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs748984440 1 dbSNP
rs371208770 4 dbSNP
rs1272402969 6 dbSNP
rs768366559 7 dbSNP
rs778358844 8 dbSNP
rs144772480 11 dbSNP
rs771561387 12 dbSNP
rs374253522 13 dbSNP
rs367809801 20 dbSNP
rs201575061 21 dbSNP
rs1159309955 27 dbSNP
rs769516531 28 dbSNP
rs1410335572 29 dbSNP
rs1046219704 37 dbSNP
rs1423738097 39 dbSNP
rs1459938559 39 dbSNP
rs1383348581 40 dbSNP
rs1169570968 41 dbSNP
rs775856114 42 dbSNP
rs1395831641 44 dbSNP
rs775012448 45 dbSNP
rs374044063 52 dbSNP
rs1335475234 56 dbSNP
rs917813568 62 dbSNP
rs202125661 64 dbSNP
rs774432825 65 dbSNP
rs1269130764 67 dbSNP
rs762001063 68 dbSNP
rs767672556 72 dbSNP
rs750489567 75 dbSNP
rs756142052 84 dbSNP
rs1249577551 87 dbSNP
rs1438175455 88 dbSNP
rs201001455 91 dbSNP
rs753667339 92 dbSNP
rs200439877 95 dbSNP
rs201676874 96 dbSNP
rs1418611973 99 dbSNP
rs1404175496 100 dbSNP
rs1347884113 106 dbSNP
rs372384354 108 dbSNP
rs770300127 109 dbSNP
rs775795841 110 dbSNP
rs111933757 112 dbSNP
rs1330516915 113 dbSNP
rs369043844 115 dbSNP
rs1413732811 116 dbSNP
rs1481115447 123 dbSNP
rs1293381502 126 dbSNP
rs1336225539 130 dbSNP
rs1216787567 131 dbSNP
rs774672415 132 dbSNP
rs376707517 135 dbSNP
rs1234890403 136 dbSNP
rs1205870489 140 dbSNP
rs753429817 143 dbSNP
rs931623857 146 dbSNP
rs187429037 156 dbSNP
rs891362263 166 dbSNP
rs1284892129 175 dbSNP
rs987423086 176 dbSNP
rs1222127052 182 dbSNP
rs578148161 186 dbSNP
rs112005313 187 dbSNP
rs1182403544 188 dbSNP
rs1377053612 196 dbSNP
rs1353903332 199 dbSNP
rs965161532 206 dbSNP
rs978846445 207 dbSNP
rs1406104557 209 dbSNP
rs112256643 213 dbSNP
rs936479141 214 dbSNP
rs988080022 218 dbSNP
rs1210630136 219 dbSNP
rs149179279 221 dbSNP
rs913819452 222 dbSNP
rs563703669 224 dbSNP
rs1232786789 225 dbSNP
rs1461834731 234 dbSNP
rs578064053 236 dbSNP
rs543089337 237 dbSNP
rs561490568 239 dbSNP
rs937769907 240 dbSNP
rs529074549 241 dbSNP
rs3025039 254 dbSNP
rs559522706 255 dbSNP
rs963141368 260 dbSNP
rs1382924269 263 dbSNP
rs1335433160 265 dbSNP
rs993623699 269 dbSNP
rs1026557481 276 dbSNP
rs973226910 277 dbSNP
rs1159368851 279 dbSNP
rs1400549113 282 dbSNP
rs1378787222 289 dbSNP
rs1185964647 290 dbSNP
rs778163655 307 dbSNP
rs890715188 308 dbSNP
rs533046584 313 dbSNP
rs551692177 314 dbSNP
rs1479430148 316 dbSNP
rs570044029 318 dbSNP
rs964713658 321 dbSNP
rs1215263426 323 dbSNP
rs537491073 325 dbSNP
rs1042624192 339 dbSNP
rs1033082420 343 dbSNP
rs549490546 345 dbSNP
rs902787596 349 dbSNP
rs1333377740 351 dbSNP
rs936794448 361 dbSNP
rs1363433630 372 dbSNP
rs1053987330 375 dbSNP
rs1289097615 375 dbSNP
rs895212897 375 dbSNP
rs567722917 377 dbSNP
rs1425661285 381 dbSNP
rs368441324 389 dbSNP
rs1186179862 390 dbSNP
rs1262436004 390 dbSNP
rs371875161 390 dbSNP
rs535119313 391 dbSNP
rs553262626 392 dbSNP
rs578135072 400 dbSNP
rs982021226 403 dbSNP
rs538948863 414 dbSNP
rs963275334 416 dbSNP
rs973196202 423 dbSNP
rs1028824123 430 dbSNP
rs1295623940 432 dbSNP
rs1213458290 434 dbSNP
rs1304581618 440 dbSNP
rs937671499 440 dbSNP
rs1238203994 443 dbSNP
rs1467779736 445 dbSNP
rs557256799 445 dbSNP
rs987593914 452 dbSNP
rs1191406667 462 dbSNP
rs1037894818 463 dbSNP
rs757492858 464 dbSNP
rs1169886788 467 dbSNP
rs1476863432 477 dbSNP
rs1378985785 479 dbSNP
rs1478270034 500 dbSNP
rs911648535 502 dbSNP
rs1266320765 506 dbSNP
rs1208019685 510 dbSNP
rs945680828 516 dbSNP
rs1251789402 522 dbSNP
rs1226146309 526 dbSNP
rs1315522300 528 dbSNP
rs929023157 540 dbSNP
rs1047886858 543 dbSNP
rs1299582804 568 dbSNP
rs1401171836 574 dbSNP
rs36001252 575 dbSNP
rs924176625 581 dbSNP
rs1440234937 583 dbSNP
rs1324204022 584 dbSNP
rs890601547 594 dbSNP
rs1333044240 601 dbSNP
rs1009117670 609 dbSNP
rs1437635641 611 dbSNP
rs559477981 617 dbSNP
rs1376875253 626 dbSNP
rs936930305 636 dbSNP
rs1039274565 643 dbSNP
rs560963332 644 dbSNP
rs1420652852 649 dbSNP
rs1251234417 650 dbSNP
rs1053956091 660 dbSNP
rs111590525 661 dbSNP
rs1203931487 663 dbSNP
rs1259234032 665 dbSNP
rs1000200646 684 dbSNP
rs1211266484 700 dbSNP
rs1269022481 702 dbSNP
rs185294556 703 dbSNP
rs956118182 710 dbSNP
rs1385119736 712 dbSNP
rs747321252 723 dbSNP
rs1187263279 728 dbSNP
rs771331791 729 dbSNP
rs906635173 730 dbSNP
rs1240099342 732 dbSNP
rs573628689 735 dbSNP
rs1364096972 742 dbSNP
rs530287018 745 dbSNP
rs1171357298 746 dbSNP
rs1437697716 748 dbSNP
rs1244871227 752 dbSNP
rs541137949 767 dbSNP
rs3025040 769 dbSNP
rs899086791 770 dbSNP
rs1206466612 771 dbSNP
rs1351851092 778 dbSNP
rs926554562 779 dbSNP
rs528762513 795 dbSNP
rs1238634262 803 dbSNP
rs750478984 806 dbSNP
rs959332666 808 dbSNP
rs973099534 816 dbSNP
rs920222087 826 dbSNP
rs1338721383 836 dbSNP
rs533184854 839 dbSNP
rs746442886 840 dbSNP
rs1019082216 841 dbSNP
rs912091383 842 dbSNP
rs769164425 848 dbSNP
rs1417601085 852 dbSNP
rs1039732235 853 dbSNP
rs114607160 855 dbSNP
rs563616137 859 dbSNP
rs1194914456 862 dbSNP
rs1447164963 869 dbSNP
rs1165908869 881 dbSNP
rs530836187 886 dbSNP
rs1054465756 888 dbSNP
rs891771619 889 dbSNP
rs778009175 892 dbSNP
rs1266641860 895 dbSNP
rs1228190758 896 dbSNP
rs1354375361 908 dbSNP
rs958268348 909 dbSNP
rs989696266 915 dbSNP
rs1204225098 920 dbSNP
rs190588351 921 dbSNP
rs1281668721 929 dbSNP
rs10434 930 dbSNP
rs1194111230 933 dbSNP
rs1046569871 935 dbSNP
rs1024374658 939 dbSNP
rs1474152384 947 dbSNP
rs970585789 948 dbSNP
rs1370228735 950 dbSNP
rs762477558 951 dbSNP
rs940800585 956 dbSNP
rs528542280 959 dbSNP
rs1802040 965 dbSNP
rs780389723 965 dbSNP
rs1458449719 966 dbSNP
rs542812735 967 dbSNP
rs1033895355 969 dbSNP
rs1158265666 984 dbSNP
rs959320221 985 dbSNP
rs41430645 994 dbSNP
rs1421982497 996 dbSNP
rs571724503 1010 dbSNP
rs1196527327 1011 dbSNP
rs889053103 1013 dbSNP
rs539264549 1015 dbSNP
rs1375393155 1025 dbSNP
rs950374975 1032 dbSNP
rs983187952 1033 dbSNP
rs911639125 1034 dbSNP
rs1347195644 1042 dbSNP
rs3025053 1043 dbSNP
rs1315397399 1049 dbSNP
rs1018802888 1052 dbSNP
rs1330804662 1060 dbSNP
rs1465703676 1061 dbSNP
rs1398840917 1066 dbSNP
rs1168139170 1073 dbSNP
rs1340601909 1074 dbSNP
rs1237683119 1076 dbSNP
rs182317842 1082 dbSNP
rs967528845 1082 dbSNP
rs1355323511 1083 dbSNP
rs1235155844 1085 dbSNP
rs974949193 1092 dbSNP
rs780075986 1095 dbSNP
rs536572716 1096 dbSNP
rs936286611 1099 dbSNP
rs1054700031 1101 dbSNP
rs1278142103 1107 dbSNP
rs1218494807 1110 dbSNP
rs747174244 1112 dbSNP
rs750140926 1112 dbSNP
rs891823874 1114 dbSNP
rs554910999 1117 dbSNP
rs946026389 1118 dbSNP
rs1045881192 1129 dbSNP
rs1328747281 1133 dbSNP
rs916787221 1141 dbSNP
rs552833857 1147 dbSNP
rs969693893 1152 dbSNP
rs907293552 1156 dbSNP
rs1424533026 1162 dbSNP
rs1001985161 1167 dbSNP
rs573618781 1169 dbSNP
rs1236857244 1176 dbSNP
rs1185538685 1177 dbSNP
rs767407432 1178 dbSNP
rs1378708490 1181 dbSNP
rs894943055 1191 dbSNP
rs994796268 1198 dbSNP
rs540750016 1199 dbSNP
rs1286032880 1205 dbSNP
rs1027510808 1224 dbSNP
rs950427338 1229 dbSNP
rs1305169953 1237 dbSNP
rs930617155 1239 dbSNP
rs1403528948 1242 dbSNP
rs553079671 1243 dbSNP
rs183460308 1261 dbSNP
rs188186771 1266 dbSNP
rs1301900924 1282 dbSNP
rs563477755 1282 dbSNP
rs1445303928 1284 dbSNP
rs889012828 1288 dbSNP
rs781756914 1289 dbSNP
rs1379071045 1295 dbSNP
rs1419446054 1295 dbSNP
rs1040602724 1306 dbSNP
rs540841861 1306 dbSNP
rs902983990 1306 dbSNP
rs1240373198 1315 dbSNP
rs1302201612 1316 dbSNP
rs1310273438 1317 dbSNP
rs1235131035 1319 dbSNP
rs1256590703 1322 dbSNP
rs1480233272 1325 dbSNP
rs1195320768 1326 dbSNP
rs530796133 1328 dbSNP
rs1242885426 1344 dbSNP
rs1217153992 1362 dbSNP
rs141683858 1366 dbSNP
rs1487833118 1367 dbSNP
rs566144283 1375 dbSNP
rs998690665 1377 dbSNP
rs1236385878 1384 dbSNP
rs561110106 1392 dbSNP
rs1179547642 1393 dbSNP
rs1394687532 1404 dbSNP
rs974876708 1412 dbSNP
rs1012981736 1420 dbSNP
rs1022651742 1422 dbSNP
rs1399841886 1428 dbSNP
rs922150020 1430 dbSNP
rs936146834 1431 dbSNP
rs866177519 1433 dbSNP
rs1035686035 1434 dbSNP
rs990438125 1439 dbSNP
rs41282644 1440 dbSNP
rs1378733321 1447 dbSNP
rs1424680592 1447 dbSNP
rs1461877796 1455 dbSNP
rs373941416 1458 dbSNP
rs1260712972 1495 dbSNP
rs972219770 1500 dbSNP
rs946247119 1502 dbSNP
rs920667200 1505 dbSNP
rs1049160 1506 dbSNP
rs1251883361 1511 dbSNP
rs986535970 1516 dbSNP
rs1217593105 1517 dbSNP
rs1338934938 1522 dbSNP
rs1285640131 1523 dbSNP
rs910587281 1526 dbSNP
rs907173870 1527 dbSNP
rs1390734609 1529 dbSNP
rs1292281454 1532 dbSNP
rs1463605064 1535 dbSNP
rs1401040618 1537 dbSNP
rs944711139 1544 dbSNP
rs181069410 1548 dbSNP
rs796446173 1551 dbSNP
rs895003063 1556 dbSNP
rs934450906 1557 dbSNP
rs1054316295 1563 dbSNP
rs1189338814 1568 dbSNP
rs1458715708 1570 dbSNP
rs1258090828 1590 dbSNP
rs1216761169 1592 dbSNP
rs994627281 1595 dbSNP
rs1259885197 1596 dbSNP
rs34241255 1598 dbSNP
rs370654536 1598 dbSNP
rs532477681 1598 dbSNP
rs147035281 1600 dbSNP
rs1377770130 1608 dbSNP
rs3025054 1613 dbSNP
rs549547019 1616 dbSNP
rs150363719 1618 dbSNP
rs995961655 1628 dbSNP
rs1173361780 1630 dbSNP
rs1466371933 1631 dbSNP
rs1029155433 1634 dbSNP
rs972188375 1639 dbSNP
rs1428258842 1653 dbSNP
rs1441524268 1657 dbSNP
rs553136985 1661 dbSNP
rs952122946 1669 dbSNP
rs1456063452 1670 dbSNP
rs1257856744 1676 dbSNP
rs1426397353 1679 dbSNP
rs1344793774 1681 dbSNP
rs957591908 1684 dbSNP
rs1242737371 1687 dbSNP
rs1355091784 1692 dbSNP
rs1309159530 1705 dbSNP
rs990322138 1707 dbSNP
rs1385009536 1709 dbSNP
rs1335108170 1714 dbSNP
rs1395626761 1715 dbSNP
rs913363312 1729 dbSNP
rs1163501700 1740 dbSNP
rs967640594 1744 dbSNP
rs796725834 1745 dbSNP
rs1380903852 1747 dbSNP
rs910629028 1749 dbSNP
rs1459081462 1766 dbSNP
rs944700713 1769 dbSNP
rs1187844012 1774 dbSNP
rs1293719095 1776 dbSNP
rs1253602433 1777 dbSNP
rs773067982 1786 dbSNP
rs778075982 1796 dbSNP
rs1219330561 1807 dbSNP
rs866951594 1809 dbSNP
rs937321687 1810 dbSNP
rs1280090418 1811 dbSNP
rs934586127 1812 dbSNP
rs1284907566 1818 dbSNP
rs567150308 1824 dbSNP
rs371781236 1834 dbSNP
rs931363788 1835 dbSNP
rs1401635629 1844 dbSNP
rs1048886254 1849 dbSNP
rs1320176024 1855 dbSNP
rs1360859863 1864 dbSNP
rs1297542595 1869 dbSNP
rs1417734801 1870 dbSNP
rs948564402 1871 dbSNP
rs1266240172 1888 dbSNP
rs1044129922 1894 dbSNP
rs1366408341 1894 dbSNP
rs869136464 1894 dbSNP
rs886252251 1895 dbSNP
rs1191952751 1896 dbSNP
rs1004772225 1897 dbSNP
rs1262868047 1899 dbSNP
rs1040674850 1900 dbSNP
rs1215113355 1901 dbSNP
rs901547945 1902 dbSNP
rs76989981 1905 dbSNP
rs534658089 1914 dbSNP
rs1209378776 1921 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Cos-7
Location of target site 3'UTR
Tools used in this research FindTar
Original Description (Extracted from the article) ... {This MTI is shown in Fig. 1 and Fig. 2} ...

- Ye W; Lv Q; Wong CK; Hu S; Fu C; Hua Z; Cai et al., 2008, PloS one.

Article - Ye W; Lv Q; Wong CK; Hu S; Fu C; Hua Z; Cai et al.
- PloS one, 2008
MicroRNAs (miRNAs) guide posttranscriptional repression of mRNAs. Hundreds of miRNAs have been identified but the target identification of mammalian mRNAs is still a difficult task due to a poor understanding of the interaction between miRNAs and the miRNA recognizing element (MRE). In recent research, the importance of the 5' end of the miRNA:MRE duplex has been emphasized and the effect of the tail region addressed, but the role of the central loop has largely remained unexplored. Here we examined the effect of the loop region in miRNA:MRE duplexes and found that the location of the central loop is one of the important factors affecting the efficiency of gene regulation mediated by miRNAs. It was further determined that the addition of a loop score combining both location and size as a new criterion for predicting MREs and their cognate miRNAs significantly decreased the false positive rates and increased the specificity of MRE prediction.
LinkOut: [PMID: 18320040]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
CHOL 0.603 0.1 0.543 0.13 6 Click to see details
LIHC -0.215 0.14 -0.264 0.09 28 Click to see details
HNSC 0.339 0.15 0.300 0.19 11 Click to see details
PRAD 0.123 0.21 0.121 0.22 44 Click to see details
PAAD -0.742 0.23 -0.500 0.33 3 Click to see details
UCEC -0.392 0.3 -0.400 0.3 4 Click to see details
BLCA 0.065 0.42 -0.045 0.45 11 Click to see details
BRCA -0.028 0.44 -0.076 0.34 30 Click to see details
LUSC 0.054 0.47 0.300 0.31 5 Click to see details
STAD -0.012 0.48 -0.038 0.44 18 Click to see details
STAD -0.012 0.48 -0.038 0.44 18 Click to see details
STAD -0.012 0.48 -0.038 0.44 18 Click to see details
STAD -0.012 0.48 -0.038 0.44 18 Click to see details
STAD -0.012 0.48 -0.038 0.44 18 Click to see details
STAD -0.012 0.48 -0.038 0.44 18 Click to see details
STAD -0.012 0.48 -0.038 0.44 18 Click to see details
STAD -0.012 0.48 -0.038 0.44 18 Click to see details
96 hsa-miR-383-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT004443 VEGFA vascular endothelial growth factor A 5 2
MIRT006137 DIO1 iodothyronine deiodinase 1 3 1
MIRT006535 IRF1 interferon regulatory factor 1 3 1
MIRT007246 IGF1R insulin like growth factor 1 receptor 1 1
MIRT007305 PRDX3 peroxiredoxin 3 1 1
MIRT054359 CCND1 cyclin D1 4 2
MIRT057087 DDIT4 DNA damage inducible transcript 4 2 2
MIRT086536 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 2
MIRT086544 MOB4 MOB family member 4, phocein 2 2
MIRT438194 PPP1R10 protein phosphatase 1 regulatory subunit 10 3 1
MIRT448282 ZMYM2 zinc finger MYM-type containing 2 2 2
MIRT451601 TRPM7 transient receptor potential cation channel subfamily M member 7 2 2
MIRT453387 RHD Rh blood group D antigen 2 2
MIRT458521 C5orf22 chromosome 5 open reading frame 22 2 2
MIRT459720 SGK494 uncharacterized serine/threonine-protein kinase SgK494 2 2
MIRT461491 KIAA1009 centrosomal protein 162 1 1
MIRT463261 ZIC5 Zic family member 5 2 2
MIRT464237 VCP valosin containing protein 2 2
MIRT465320 TRAF5 TNF receptor associated factor 5 2 2
MIRT465774 TMOD3 tropomodulin 3 2 2
MIRT467879 SLC22A23 solute carrier family 22 member 23 2 2
MIRT469636 RAD21 RAD21 cohesin complex component 2 6
MIRT472041 NPAT nuclear protein, coactivator of histone transcription 2 2
MIRT476568 GABARAPL1 GABA type A receptor associated protein like 1 2 2
MIRT478586 CTDSPL2 CTD small phosphatase like 2 2 2
MIRT478870 CREBRF CREB3 regulatory factor 2 2
MIRT482202 AHR aryl hydrocarbon receptor 2 2
MIRT484237 IER2 immediate early response 2 2 2
MIRT487480 NRF1 nuclear respiratory factor 1 2 6
MIRT493746 GRAP2 GRB2-related adaptor protein 2 2 2
MIRT496836 ZNF460 zinc finger protein 460 2 2
MIRT497234 APOL2 apolipoprotein L2 2 2
MIRT499424 PLCG2 phospholipase C gamma 2 2 9
MIRT500598 UBN2 ubinuclein 2 2 10
MIRT502859 CHEK2 checkpoint kinase 2 2 6
MIRT507727 CLIC4 chloride intracellular channel 4 2 4
MIRT510509 YOD1 YOD1 deubiquitinase 2 6
MIRT511901 FNBP1L formin binding protein 1 like 2 6
MIRT514393 CLUAP1 clusterin associated protein 1 2 2
MIRT520180 WBP2 WW domain binding protein 2 2 4
MIRT531214 PLA2G4D phospholipase A2 group IVD 2 2
MIRT532846 ZNF699 zinc finger protein 699 2 2
MIRT533461 TRIM71 tripartite motif containing 71 2 2
MIRT539263 ANKRD44 ankyrin repeat domain 44 2 2
MIRT539380 ADSS adenylosuccinate synthase 2 6
MIRT548129 GAS1 growth arrest specific 1 2 2
MIRT550662 ZFP37 ZFP37 zinc finger protein 2 2
MIRT551499 CENPN centromere protein N 2 2
MIRT553778 TAF13 TATA-box binding protein associated factor 13 2 2
MIRT554376 SFPQ splicing factor proline and glutamine rich 2 2
MIRT555821 PCDH11Y protocadherin 11 Y-linked 2 4
MIRT557558 GOSR1 golgi SNAP receptor complex member 1 2 2
MIRT557694 GATA6 GATA binding protein 6 2 2
MIRT561383 TWF1 twinfilin actin binding protein 1 2 2
MIRT561414 TSN translin 2 2
MIRT561867 MSH6 mutS homolog 6 2 2
MIRT567383 GTPBP3 GTP binding protein 3, mitochondrial 2 2
MIRT569272 PCDH11X protocadherin 11 X-linked 2 2
MIRT569556 UNC119B unc-119 lipid binding chaperone B 2 2
MIRT569760 RIMBP3C RIMS binding protein 3C 2 5
MIRT573387 GGA2 golgi associated, gamma adaptin ear containing, ARF binding protein 2 2 2
MIRT573456 RPL41 ribosomal protein L41 2 2
MIRT573968 DDX21 DExD-box helicase 21 2 2
MIRT574163 ATG10 autophagy related 10 2 2
MIRT574659 KLHL15 kelch like family member 15 2 2
MIRT574907 Plcg2 phospholipase C, gamma 2 2 6
MIRT607496 HEBP2 heme binding protein 2 2 2
MIRT612840 KCNJ12 potassium voltage-gated channel subfamily J member 12 2 4
MIRT613962 TMEM59 transmembrane protein 59 2 2
MIRT621125 PCNXL2 pecanex homolog 2 2 2
MIRT625216 SH3TC2 SH3 domain and tetratricopeptide repeats 2 2 2
MIRT643337 MICA MHC class I polypeptide-related sequence A 2 2
MIRT646342 CLIC6 chloride intracellular channel 6 2 2
MIRT647361 WDR5B WD repeat domain 5B 2 2
MIRT650308 SLC35E2 solute carrier family 35 member E2 2 2
MIRT651372 ZBTB21 zinc finger and BTB domain containing 21 2 2
MIRT655301 PEAR1 platelet endothelial aggregation receptor 1 2 2
MIRT681918 SLC11A2 solute carrier family 11 member 2 2 2
MIRT684165 ALDH1B1 aldehyde dehydrogenase 1 family member B1 2 2
MIRT688053 GLUL glutamate-ammonia ligase 2 2
MIRT690210 C5orf45 MRN complex interacting protein 2 2
MIRT691024 CRTC3 CREB regulated transcription coactivator 3 2 2
MIRT697699 WAC WW domain containing adaptor with coiled-coil 2 2
MIRT698201 TMEM30A transmembrane protein 30A 2 2
MIRT698857 SRSF2 serine and arginine rich splicing factor 2 2 2
MIRT702292 LDHA lactate dehydrogenase A 4 2
MIRT703341 GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2 2
MIRT704082 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 2 2
MIRT713729 SUCO SUN domain containing ossification factor 2 2
MIRT719487 RBM27 RNA binding motif protein 27 2 2
MIRT722080 SMC2 structural maintenance of chromosomes 2 2 2
MIRT724102 TMEM199 transmembrane protein 199 2 2
MIRT725124 SYNRG synergin gamma 2 2
MIRT725601 CAPN6 calpain 6 2 2
MIRT737186 RBM3 RNA binding motif (RNP1, RRM) protein 3 4 0
MIRT755379 NOS3 nitric oxide synthase 3 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-383 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miR-383 Vorinostat (SAHA) approved 5311 Microarray A549 human non-small cell lung cancer cells 19513533 2009 up-regulated
miR-383 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miR-383 Doxorubicin approved 31703 Microarray heart 22859947 2012 up-regulated
miR-383 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 down-regulated
miR-383 Tert-butyl hydroperoxide (t-BHP) NULL 6410 Microarray mouse auditory cells 20510889 2010 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-383-5p Vincristine 5978 approved resistant High Lymphoblastic Leukemia tissue
hsa-miR-383-5p Daunorubicin 30323 NSC82151 approved resistant High Lymphoblastic Leukemia tissue
hsa-miR-383-5p Prednisolone 5755 NSC9120 approved resistant High Lymphoblastic Leukemia tissue
hsa-miR-383-5p L-Asparaginase resistant High Lymphoblastic Leukemia tissue
hsa-miR-383-5p Cisplatin 5460033 NSC119875 approved resistant High Germ Cell Tumor cell line (NTERA-2)
hsa-miR-383-5p Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer cell line (RKO)
hsa-miR-383-5p Oxaliplatin 6857599 NSC266046 approved resistant High Colorectal Cancer cell line (HT-29)
hsa-miR-383-5p Cisplatin 5460033 NSC119875 approved sensitive High Ovarian Cancer cell line (SKOV3)
hsa-miR-383-5p Docetaxel 148124 NSC628503 approved sensitive High Prostate Cancer cell line (PC-3)
hsa-miR-383-5p Cetuximab sensitive High Colon Cancer cell line
hsa-miR-383-5p Paclitaxel 36314 NSC125973 approved sensitive Low Ovarian Cancer cell line (OVCAR3, A2780)
hsa-miR-383-5p Doxorubicin 31703 NSC123127 approved sensitive Low Hepatocellular Carcinoma cell line (BT-474, SKBR3)
hsa-miR-383-5p Cetuximab + Folfox(Fluorouracil + Leucovorin + Oxaliplatin) resistant High Metastatic Colorectal Cancer tissue
hsa-miR-383-5p Gemcitabine 60750 NSC613327 approved sensitive Low Pancreatic Ductal Adenocarcinoma tissue
hsa-miR-383-5p Fluorouracil 3385 NSC19893 approved sensitive Low Gastric Cancer cell line (AGS)
hsa-miR-383-5p Oxaliplatin 6857599 NSC266046 approved resistant Low Hepatocellular Carcinoma cell line (Hep3B, Huh-7)
hsa-miR-383-5p Cisplatin 5460033 NSC119875 approved sensitive Low Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-383-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-383-5p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-383-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-383-5p Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-383-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-383-5p Fluorouracil 3385 NSC19893 approved resistant cell line (KM12C) (72 h)
hsa-miR-383-5p Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-miR-383-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-383-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-383-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-383-5p Cetuximab resistant tissue (colorectal carcinoma)

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