miRTarBase - #MIRT004490


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pre-miRNA Information
pre-miRNA hsa-let-7g   
Genomic Coordinates chr3: 52268278 - 52268361
Synonyms LET7G, MIRNLET7G, hsa-let-7g, MIRLET7G
Description Homo sapiens let-7g stem-loop
Comment let-7g-3p cloned in has a 1 nt 3' extension (U), which is incompatible with the genome sequence.
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-let-7g-5p
Sequence 5| UGAGGUAGUAGUUUGUACAGUU |26
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 7 3 - 52268351 18684997 MiREDiBase
A-to-I 10 3 - 52268348 18684997, 29950133, 29233923 MiREDiBase
A-to-I 17 3 - 52268341 29233923 MiREDiBase
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN1278471 5 COSMIC
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol BCL2L1   
Synonyms BCL-XL/S, BCL2L, BCLX, Bcl-X, PPP1R52
Description BCL2 like 1
Transcript NM_138578   
Other Transcripts NM_001191   
Expression
Putative miRNA Targets on BCL2L1
3'UTR of BCL2L1
(miRNA target sites are highlighted)		 
>BCL2L1|NM_138578|3'UTR
   1 CCAGACACTGACCATCCACTCTACCCTCCCACCCCCTTCTCTGCTCCACCACATCCTCCGTCCAGCCGCCATTGCCACCA
  81 GGAGAACCACTACATGCAGCCCATGCCCACCTGCCCATCACAGGGTTGGGCCCAGATCTGGTCCCTTGCAGCTAGTTTTC
 161 TAGAATTTATCACACTTCTGTGAGACCCCCACACCTCAGTTCCCTTGGCCTCAGAATTCACAAAATTTCCACAAAATCTG
 241 TCCAAAGGAGGCTGGCAGGTATGGAAGGGTTTGTGGCTGGGGGCAGGAGGGCCCTACCTGATTGGTGCAACCCTTACCCC
 321 TTAGCCTCCCTGAAAATGTTTTTCTGCCAGGGAGCTTGAAAGTTTTCAGAACCTCTTCCCCAGAAAGGAGACTAGATTGC
 401 CTTTGTTTTGATGTTTGTGGCCTCAGAATTGATCATTTTCCCCCCACTCTCCCCACACTAACCTGGGTTCCCTTTCCTTC
 481 CATCCCTACCCCCTAAGAGCCATTTAGGGGCCACTTTTGACTAGGGATTCAGGCTGCTTGGGATAAAGATGCAAGGACCA
 561 GGACTCCCTCCTCACCTCTGGACTGGCTAGAGTCCTCACTCCCAGTCCAAATGTCCTCCAGAAGCCTCTGGCTAGAGGCC
 641 AGCCCCACCCAGGAGGGAGGGGGCTATAGCTACAGGAAGCACCCCATGCCAAAGCTAGGGTGGCCCTTGCAGTTCAGCAC
 721 CACCCTAGTCCCTTCCCCTCCCTGGCTCCCATGACCATACTGAGGGACCAACTGGGCCCAAGACAGATGCCCCAGAGCTG
 801 TTTATGGCCTCAGCTGCCTCACTTCCTACAAGAGCAGCCTGTGGCATCTTTGCCTTGGGCTGCTCCTCATGGTGGGTTCA
 881 GGGGACTCAGCCCTGAGGTGAAAGGGAGCTATCAGGAACAGCTATGGGAGCCCCAGGGTCTTCCCTACCTCAGGCAGGAA
 961 GGGCAGGAAGGAGAGCCTGCTGCATGGGGTGGGGTAGGGCTGACTAGAAGGGCCAGTCCTGCCTGGCCAGGCAGATCTGT
1041 GCCCCATGCCTGTCCAGCCTGGGCAGCCAGGCTGCCAAGGCCAGAGTGGCCTGGCCAGGAGCTCTTCAGGCCTCCCTCTC
1121 TCTTCTGCTCCACCCTTGGCCTGTCTCATCCCCAGGGGTCCCAGCCACCCCGGGCTCTCTGCTGTACATATTTGAGACTA
1201 GTTTTTATTCCTTGTGAAGATGATATACTATTTTTGTTAAGCGTGTCTGTATTTATGTGTGAGGAGCTGCTGGCTTGCAG
1281 TGCGCGTGCACGTGGAGAGCTGGTGCCCGGAGATTGGACGGCCTGATGCTCCCTCCCCTGCCCTGGTCCAGGGAAGCTGG
1361 CCGAGGGTCCTGGCTCCTGAGGGGCATCTGCCCCTCCCCCAACCCCCACCCCACACTTGTTCCAGCTCTTTGAAATAGTC
1441 TGTGTGAAGGTGAAAGTGCAGTTCAGTAATAAACTGTGTTTACTCAGTGAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuGAC--AUGUUUGA--UGAUGGAGu 5'
            |||  ||::: ||  :||:|||| 
Target 5' agCTGTTTATGGCCTCAGCTGCCTCa 3'
 796 - 821 140.00 -15.60
2 
miRNA  3' uugacauguuugauGAUGGAGu 5'
                        ||||||| 
Target 5' ccccagggtcttccCTACCTCa 3'
 931 - 952 140.00 -12.10
3 
miRNA  3' uuGACAUGUUUGAUGAUGGAGu 5'
            || | ||::|  || |||| 
Target 5' agCTCTTCAGGC--CTCCCTCt 3'
 1100 - 1119 124.00 -9.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30516422 12 COSMIC
COSN30153975 21 COSMIC
COSN30477605 36 COSMIC
COSN30591120 53 COSMIC
COSN30462607 59 COSMIC
COSN30496869 60 COSMIC
COSN24387724 68 COSMIC
COSN31501279 82 COSMIC
COSN31575007 84 COSMIC
COSN30181223 101 COSMIC
COSN30141227 146 COSMIC
COSN31573807 167 COSMIC
COSN31522982 174 COSMIC
COSN26676840 209 COSMIC
COSN15659943 294 COSMIC
COSN31515077 365 COSMIC
COSN32099867 390 COSMIC
COSN31489757 614 COSMIC
COSN24266726 628 COSMIC
COSN31528278 686 COSMIC
COSN1869589 930 COSMIC
COSN1869588 931 COSMIC
COSN30443842 987 COSMIC
COSN1247448 999 COSMIC
COSN31521406 1108 COSMIC
COSN30162334 1179 COSMIC
COSN22782259 1308 COSMIC
COSN5802493 1388 COSMIC
COSN28816001 1401 COSMIC
COSN14563075 1408 COSMIC
COSN28198296 1411 COSMIC
COSN21016819 1414 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs781506995 6 dbSNP
rs757800093 8 dbSNP
rs751808059 11 dbSNP
rs1244379117 18 dbSNP
rs1246086266 19 dbSNP
rs764588065 19 dbSNP
rs1451150656 20 dbSNP
rs1216554681 25 dbSNP
rs754613701 26 dbSNP
rs753539518 27 dbSNP
rs765845311 35 dbSNP
rs1030657544 36 dbSNP
rs769154919 42 dbSNP
rs760138522 44 dbSNP
rs989916889 46 dbSNP
rs1243372307 48 dbSNP
rs1204774379 50 dbSNP
rs554584920 59 dbSNP
rs967769834 60 dbSNP
rs936677262 62 dbSNP
rs926738457 64 dbSNP
rs1401962362 67 dbSNP
rs980839387 68 dbSNP
rs969871111 79 dbSNP
rs1189056795 85 dbSNP
rs1266419496 98 dbSNP
rs1431216831 106 dbSNP
rs536243459 109 dbSNP
rs1022080146 114 dbSNP
rs1378390732 115 dbSNP
rs1456868565 116 dbSNP
rs1024061730 117 dbSNP
rs992719994 121 dbSNP
rs950656912 123 dbSNP
rs11550475 125 dbSNP
rs1366019003 128 dbSNP
rs1388859223 130 dbSNP
rs1439561988 133 dbSNP
rs1012013351 136 dbSNP
rs565690849 141 dbSNP
rs10861 152 dbSNP
rs1026219616 153 dbSNP
rs1227351857 169 dbSNP
rs1469106584 175 dbSNP
rs1035270230 180 dbSNP
rs1265066225 187 dbSNP
rs1219594547 188 dbSNP
rs994947146 189 dbSNP
rs1211389391 191 dbSNP
rs963075237 194 dbSNP
rs1003429993 202 dbSNP
rs1284972258 203 dbSNP
rs1180214408 207 dbSNP
rs886391008 208 dbSNP
rs1007283064 217 dbSNP
rs890642399 245 dbSNP
rs1239403000 248 dbSNP
rs1211982630 251 dbSNP
rs1459857115 254 dbSNP
rs1294518867 257 dbSNP
rs1370266387 264 dbSNP
rs1051910841 282 dbSNP
rs1047719179 288 dbSNP
rs1305403228 290 dbSNP
rs1441336995 293 dbSNP
rs1351870582 294 dbSNP
rs1009721157 298 dbSNP
rs1311981294 300 dbSNP
rs1366585869 302 dbSNP
rs1246818848 305 dbSNP
rs1291463957 314 dbSNP
rs770055952 320 dbSNP
rs34865640 331 dbSNP
rs1203367777 339 dbSNP
rs1254213489 342 dbSNP
rs1481030032 344 dbSNP
rs553661086 346 dbSNP
rs538525918 355 dbSNP
rs899244011 357 dbSNP
rs1345286656 360 dbSNP
rs1039065909 373 dbSNP
rs1390006220 378 dbSNP
rs1428216419 383 dbSNP
rs943451680 393 dbSNP
rs936669303 394 dbSNP
rs912030586 421 dbSNP
rs1301760882 425 dbSNP
rs1175975823 438 dbSNP
rs1230017270 439 dbSNP
rs1315641317 440 dbSNP
rs1341251098 441 dbSNP
rs1434147554 442 dbSNP
rs926610351 445 dbSNP
rs1308337516 446 dbSNP
rs1209595844 452 dbSNP
rs1267028357 456 dbSNP
rs1189703298 467 dbSNP
rs571443689 471 dbSNP
rs1045137100 472 dbSNP
rs988079245 477 dbSNP
rs1247914621 482 dbSNP
rs1264078411 484 dbSNP
rs745601479 485 dbSNP
rs924878889 492 dbSNP
rs549690378 493 dbSNP
rs1449547207 495 dbSNP
rs531471504 499 dbSNP
rs1351481436 502 dbSNP
rs1337370233 510 dbSNP
rs950573836 520 dbSNP
rs977738014 526 dbSNP
rs1364404340 533 dbSNP
rs967674861 537 dbSNP
rs1021986730 549 dbSNP
rs990531438 570 dbSNP
rs1282410414 574 dbSNP
rs959393524 575 dbSNP
rs919209235 576 dbSNP
rs1362322222 581 dbSNP
rs1034853217 586 dbSNP
rs567358983 588 dbSNP
rs1003826513 590 dbSNP
rs1314061712 599 dbSNP
rs886341110 604 dbSNP
rs112085564 610 dbSNP
rs527283085 611 dbSNP
rs994726961 617 dbSNP
rs1017242553 619 dbSNP
rs1190998136 624 dbSNP
rs756689819 628 dbSNP
rs1477903211 631 dbSNP
rs1190313769 639 dbSNP
rs1422598302 648 dbSNP
rs954468617 650 dbSNP
rs1362224634 656 dbSNP
rs1297091899 657 dbSNP
rs1455587429 659 dbSNP
rs116990630 660 dbSNP
rs1009778373 667 dbSNP
rs1376694397 674 dbSNP
rs1039018055 676 dbSNP
rs770813221 678 dbSNP
rs747000648 680 dbSNP
rs1377474392 686 dbSNP
rs905208400 703 dbSNP
rs1045066584 712 dbSNP
rs541725032 717 dbSNP
rs1051918296 718 dbSNP
rs934851519 724 dbSNP
rs1248781577 731 dbSNP
rs924784207 736 dbSNP
rs777327056 738 dbSNP
rs1410656541 743 dbSNP
rs558611326 746 dbSNP
rs1160265045 751 dbSNP
rs914879726 760 dbSNP
rs990927727 766 dbSNP
rs532665035 768 dbSNP
rs1367131681 769 dbSNP
rs1405843973 771 dbSNP
rs560997987 771 dbSNP
rs1348751835 777 dbSNP
rs1230279923 792 dbSNP
rs1280165152 806 dbSNP
rs1356304108 814 dbSNP
rs757916272 816 dbSNP
rs927726767 822 dbSNP
rs116239579 825 dbSNP
rs950577686 829 dbSNP
rs1026123997 832 dbSNP
rs1482879175 835 dbSNP
rs1222853389 837 dbSNP
rs1250570354 840 dbSNP
rs994679279 844 dbSNP
rs755868976 845 dbSNP
rs752260890 855 dbSNP
rs778372909 856 dbSNP
rs963297847 859 dbSNP
rs1254099326 865 dbSNP
rs1161332555 869 dbSNP
rs1386934123 872 dbSNP
rs543647087 876 dbSNP
rs1007995653 877 dbSNP
rs184626287 884 dbSNP
rs1329633220 886 dbSNP
rs1339891380 893 dbSNP
rs1052251835 897 dbSNP
rs1286459966 904 dbSNP
rs957105328 908 dbSNP
rs1216335005 909 dbSNP
rs750779574 911 dbSNP
rs3208680 914 dbSNP
rs998965064 919 dbSNP
rs1272868134 923 dbSNP
rs1312939254 924 dbSNP
rs1339671718 930 dbSNP
rs903310810 931 dbSNP
rs1197113435 932 dbSNP
rs3208681 933 dbSNP
rs3208682 934 dbSNP
rs3208683 938 dbSNP
rs1043257240 943 dbSNP
rs3208684 947 dbSNP
rs554647826 962 dbSNP
rs947612698 966 dbSNP
rs1185381532 967 dbSNP
rs1244872626 975 dbSNP
rs916206720 979 dbSNP
rs1402079072 982 dbSNP
rs1001422125 984 dbSNP
rs768032844 988 dbSNP
rs1463871491 991 dbSNP
rs542672064 993 dbSNP
rs1168703120 1011 dbSNP
rs1401668119 1014 dbSNP
rs192023484 1017 dbSNP
rs1339323713 1023 dbSNP
rs1384208295 1024 dbSNP
rs937704469 1028 dbSNP
rs1013582422 1030 dbSNP
rs553855036 1039 dbSNP
rs1328507787 1042 dbSNP
rs1476932291 1043 dbSNP
rs1251497143 1052 dbSNP
rs1420185462 1053 dbSNP
rs1343735626 1056 dbSNP
rs1188329969 1057 dbSNP
rs927665237 1058 dbSNP
rs758028362 1062 dbSNP
rs1198256055 1064 dbSNP
rs1264420896 1067 dbSNP
rs1187793841 1071 dbSNP
rs745345322 1073 dbSNP
rs1430075342 1074 dbSNP
rs1194212485 1076 dbSNP
rs982246124 1076 dbSNP
rs1477133801 1077 dbSNP
rs1178715471 1078 dbSNP
rs1406832982 1087 dbSNP
rs950479047 1092 dbSNP
rs1457189941 1093 dbSNP
rs919083667 1102 dbSNP
rs1387647930 1107 dbSNP
rs1383104954 1114 dbSNP
rs1047144314 1115 dbSNP
rs930050069 1116 dbSNP
rs1197438126 1120 dbSNP
rs1221237965 1125 dbSNP
rs1284666450 1127 dbSNP
rs1323614461 1128 dbSNP
rs1458073735 1130 dbSNP
rs537018288 1134 dbSNP
rs963245815 1135 dbSNP
rs1196434090 1136 dbSNP
rs1266357342 1145 dbSNP
rs1431661789 1148 dbSNP
rs1336482604 1151 dbSNP
rs1037564035 1155 dbSNP
rs188120954 1159 dbSNP
rs1472302496 1161 dbSNP
rs1007487936 1171 dbSNP
rs1338141277 1172 dbSNP
rs1454727310 1184 dbSNP
rs1311245855 1187 dbSNP
rs1439613768 1188 dbSNP
rs1393578586 1199 dbSNP
rs1378129250 1210 dbSNP
rs368749245 1217 dbSNP
rs910510174 1220 dbSNP
rs954847298 1225 dbSNP
rs1227216518 1226 dbSNP
rs1304169504 1229 dbSNP
rs1331082592 1240 dbSNP
rs1318688259 1242 dbSNP
rs1030332085 1243 dbSNP
rs1239596198 1246 dbSNP
rs1464323762 1249 dbSNP
rs752115367 1251 dbSNP
rs1163963370 1256 dbSNP
rs1457491030 1267 dbSNP
rs1269843260 1273 dbSNP
rs1482823858 1274 dbSNP
rs1180148264 1277 dbSNP
rs1252678512 1278 dbSNP
rs867739143 1281 dbSNP
rs922902117 1283 dbSNP
rs903304395 1284 dbSNP
rs988311854 1285 dbSNP
rs956504890 1286 dbSNP
rs184805060 1291 dbSNP
rs554667741 1292 dbSNP
rs1295947703 1305 dbSNP
rs1011777629 1308 dbSNP
rs979657125 1314 dbSNP
rs537638536 1319 dbSNP
rs1208829342 1322 dbSNP
rs759097020 1322 dbSNP
rs1056422275 1328 dbSNP
rs938965741 1329 dbSNP
rs1292181067 1332 dbSNP
rs1341730541 1335 dbSNP
rs1202627574 1338 dbSNP
rs906153196 1349 dbSNP
rs1261912657 1357 dbSNP
rs1046098430 1362 dbSNP
rs865787655 1363 dbSNP
rs1241808467 1372 dbSNP
rs1446917838 1373 dbSNP
rs929055673 1379 dbSNP
rs567420266 1388 dbSNP
rs1389864939 1392 dbSNP
rs1309042682 1393 dbSNP
rs753679722 1395 dbSNP
rs1325159273 1404 dbSNP
rs1355842491 1408 dbSNP
rs908701953 1408 dbSNP
rs1462023611 1410 dbSNP
rs549105385 1416 dbSNP
rs973197792 1422 dbSNP
rs1380534907 1423 dbSNP
rs1454446190 1424 dbSNP
rs527346866 1450 dbSNP
rs1364181676 1452 dbSNP
rs898608725 1462 dbSNP
rs1324497112 1464 dbSNP
rs1386366488 1466 dbSNP
rs910403008 1467 dbSNP
rs986411458 1474 dbSNP
rs138866312 1475 dbSNP
rs1030742158 1487 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HepG2 , Huh7
Disease 598.0;
Location of target site 3'UTR
Original Description (Extracted from the article) ... "Over-expression of let-7c or let-7g led to a clear decrease of Bcl-xL expression in Huh7 and HepG2 cel lines. Reporter assays revealed direct post-transcriptional regulation involving let-7c or let-7g and the 30-untranslated region of bcl-xl mRNA.//let-7c and let-7g downregulate Bcl-xL expression by directly targeting the 30UTR of bcl-xl mRNA//In conclusion ...

- Shimizu S; Takehara T; Hikita H; Kodama T; et al., 2010, Journal of hepatology.

Article - Shimizu S; Takehara T; Hikita H; Kodama T; et al.
- Journal of hepatology, 2010
BACKGROUND & AIMS: Bcl-xL, an anti-apoptotic member of the Bcl-2 family, is over-expressed in human hepatocellular carcinoma, conferring a survival advantage to tumour cells. The mechanisms underlying its dysregulation have not been clarified. In the present study, we explored the involvement of microRNAs that act as endogenous sequence-specific suppressors of gene expression. METHODS: The expression profiles of microRNAs in Huh7 hepatoma cells and primary human hepatocytes were compared by microarray analysis. The effect of let-7 on Bcl-xL expression was examined by Western blot and a reporter assay. The involvement of let-7 microRNAs in human tissues was analysed by western blot and reverse transcription-PCR. RESULTS: Microarray analysis, followed by in silico target prediction, identified let-7 microRNAs as being downregulated in Huh7 hepatoma cells in comparison with primary human hepatocytes, as well as possessing a putative target site in the bcl-xl mRNA. Over-expression of let-7c or let-7g led to a clear decrease of Bcl-xL expression in Huh7 and HepG2 cell lines. Reporter assays revealed direct post-transcriptional regulation involving let-7c or let-7g and the 3'-untranslated region of bcl-xl mRNA. Human hepatocellular carcinoma tissues with low expression of let-7c displayed higher expression of Bcl-xL protein than those with high expression of let-7c, suggesting that low let-7 microRNA expression contributes to Bcl-xL over-expression. Finally, expression of let-7c enhanced apoptosis of hepatoma cells upon exposure to sorafenib, which downregulates expression of another anti-apoptotic Bcl-2 protein, Mcl-1. CONCLUSIONS: let-7 microRNAs negatively regulate Bcl-xL expression in human hepatocellular carcinomas and induce apoptosis in cooperation with an anti-cancer drug targeting Mcl-1.
LinkOut: [PMID: 20347499]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
STAD 0.607 0 0.608 0 32 Click to see details
BRCA -0.243 0.01 -0.227 0.02 84 Click to see details
BLCA 0.488 0.02 0.439 0.03 18 Click to see details
COAD 0.656 0.04 0.476 0.12 8 Click to see details
KIRC 0.198 0.05 0.230 0.03 68 Click to see details
PAAD -0.846 0.08 -1.000 0.5 4 Click to see details
LIHC 0.206 0.08 0.076 0.3 49 Click to see details
KICH -0.28 0.09 -0.191 0.18 25 Click to see details
LUSC 0.179 0.14 0.072 0.33 38 Click to see details
THCA -0.126 0.17 -0.096 0.23 59 Click to see details
HNSC -0.138 0.19 -0.103 0.26 42 Click to see details
PRAD 0.118 0.21 0.122 0.2 50 Click to see details
ESCA 0.272 0.21 0.200 0.28 11 Click to see details
KIRP -0.109 0.28 -0.167 0.18 32 Click to see details
UCEC -0.127 0.3 -0.139 0.29 19 Click to see details
CHOL -0.194 0.31 -0.250 0.26 9 Click to see details
CESC 0.462 0.35 0.500 0.33 3 Click to see details
PCPG -0.413 0.36 -0.500 0.33 3 Click to see details
LUAD 0.106 0.37 0.070 0.41 12 Click to see details
LUAD 0.106 0.37 0.070 0.41 12 Click to see details
LUAD 0.106 0.37 0.070 0.41 12 Click to see details
310 hsa-let-7g-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT000396 CDK6 cyclin dependent kinase 6 1 1
MIRT000397 CDC25A cell division cycle 25A 1 1
MIRT000399 KRAS KRAS proto-oncogene, GTPase 2 2
MIRT000472 COL1A2 collagen type I alpha 2 chain 4 1
MIRT000475 MYC MYC proto-oncogene, bHLH transcription factor 4 3
MIRT002097 HMGA2 high mobility group AT-hook 2 6 8
MIRT003831 IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 6 4
MIRT004489 CDKN2A cyclin dependent kinase inhibitor 2A 4 1
MIRT004490 BCL2L1 BCL2 like 1 4 1
MIRT006161 GAB2 GRB2 associated binding protein 2 3 1
MIRT006162 FN1 fibronectin 1 3 1
MIRT006399 IL13 interleukin 13 2 1
MIRT024117 DAD1 defender against cell death 1 1 1
MIRT024118 EIF4G2 eukaryotic translation initiation factor 4 gamma 2 3 5
MIRT024119 TBC1D9 TBC1 domain family member 9 2 1
MIRT024120 BMI1 BMI1 proto-oncogene, polycomb ring finger 2 1
MIRT046555 DCAF8 DDB1 and CUL4 associated factor 8 1 1
MIRT046556 EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1 1
MIRT046557 UBE3C ubiquitin protein ligase E3C 1 1
MIRT046558 RPL12 ribosomal protein L12 1 1
MIRT046559 SFT2D1 SFT2 domain containing 1 1 1
MIRT046560 MAP3K1 mitogen-activated protein kinase kinase kinase 1 1 1
MIRT046561 BRD1 bromodomain containing 1 1 1
MIRT046562 AGO1 argonaute 1, RISC catalytic component 4 2
MIRT046563 RAB21 RAB21, member RAS oncogene family 1 1
MIRT046564 HMGB1 high mobility group box 1 1 1
MIRT046565 RRM2 ribonucleotide reductase regulatory subunit M2 2 3
MIRT046566 AKAP11 A-kinase anchoring protein 11 1 1
MIRT046567 RANBP2 RAN binding protein 2 1 1
MIRT046568 SART3 squamous cell carcinoma antigen recognized by T-cells 3 1 1
MIRT054642 CASP3 caspase 3 2 1
MIRT054662 THBS1 thrombospondin 1 5 4
MIRT054663 TGFBR1 transforming growth factor beta receptor 1 3 1
MIRT054664 SMAD2 SMAD family member 2 3 1
MIRT063199 ADIPOR2 adiponectin receptor 2 2 2
MIRT065691 ESPL1 extra spindle pole bodies like 1, separase 2 4
MIRT067403 TMTC3 transmembrane and tetratricopeptide repeat containing 3 2 2
MIRT068157 TXLNA taxilin alpha 2 2
MIRT068532 NHLRC3 NHL repeat containing 3 2 6
MIRT068792 FNDC3A fibronectin type III domain containing 3A 2 2
MIRT073008 ARID3B AT-rich interaction domain 3B 2 6
MIRT073672 IGF1R insulin like growth factor 1 receptor 2 8
MIRT076227 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 6
MIRT080402 ONECUT2 one cut homeobox 2 2 2
MIRT083304 ZCCHC3 zinc finger CCHC-type containing 3 2 2
MIRT084979 BACH1 BTB domain and CNC homolog 1 2 2
MIRT094164 PCGF3 polycomb group ring finger 3 2 6
MIRT094464 SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 2 4
MIRT095770 GRPEL2 GrpE like 2, mitochondrial 2 10
MIRT100096 ABT1 activator of basal transcription 1 2 8
MIRT112245 MDM4 MDM4, p53 regulator 2 4
MIRT118589 STK4 serine/threonine kinase 4 2 2
MIRT120924 PDE12 phosphodiesterase 12 2 8
MIRT123321 CALU calumenin 2 2
MIRT123980 POLR3D RNA polymerase III subunit D 2 2
MIRT152281 TNFSF9 TNF superfamily member 9 2 2
MIRT153856 NCOA3 nuclear receptor coactivator 3 2 2
MIRT168587 HMGA1 high mobility group AT-hook 1 2 4
MIRT180606 CRY2 cryptochrome circadian clock 2 2 2
MIRT187721 SUOX sulfite oxidase 2 2
MIRT191407 NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit 2 2
MIRT193104 MAPK6 mitogen-activated protein kinase 6 2 2
MIRT215724 C5ORF51 chromosome 5 open reading frame 51 2 10
MIRT218816 CDKN1A cyclin dependent kinase inhibitor 1A 2 2
MIRT240333 UBXN2B UBX domain protein 2B 2 2
MIRT243476 TRIM71 tripartite motif containing 71 2 2
MIRT244074 EDN1 endothelin 1 2 2
MIRT252334 SALL3 spalt like transcription factor 3 2 2
MIRT255318 CDV3 CDV3 homolog 2 2
MIRT259280 PGRMC1 progesterone receptor membrane component 1 2 2
MIRT259483 TXLNG taxilin gamma 2 2
MIRT260711 CLDN12 claudin 12 2 6
MIRT264695 C11ORF57 chromosome 11 open reading frame 57 2 4
MIRT266216 PEX11B peroxisomal biogenesis factor 11 beta 2 2
MIRT266629 CHTOP chromatin target of PRMT1 2 2
MIRT268842 C1ORF21 chromosome 1 open reading frame 21 2 2
MIRT284531 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT294449 ZNF264 zinc finger protein 264 2 2
MIRT297445 SLC20A1 solute carrier family 20 member 1 2 4
MIRT300041 BZW1 basic leucine zipper and W2 domains 1 2 4
MIRT300896 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT303323 MXD1 MAX dimerization protein 1 2 2
MIRT309849 NAT8L N-acetyltransferase 8 like 2 2
MIRT322431 PPP2R2A protein phosphatase 2 regulatory subunit Balpha 2 2
MIRT324735 ACER2 alkaline ceramidase 2 2 2
MIRT402061 ATP6V1F ATPase H+ transporting V1 subunit F 2 4
MIRT437976 AKT2 AKT serine/threonine kinase 2 3 1
MIRT438631 TNFRSF10B TNF receptor superfamily member 10b 2 1
MIRT442018 NDUFA4P1 NDUFA4, mitochondrial complex associated pseudogene 1 2 2
MIRT445656 ATP6V1G1 ATPase H+ transporting V1 subunit G1 2 6
MIRT447134 KIF27 kinesin family member 27 2 2
MIRT448256 ZNF774 zinc finger protein 774 2 2
MIRT449009 ANKRD46 ankyrin repeat domain 46 2 2
MIRT449951 FMNL3 formin like 3 2 2
MIRT451153 C19orf53 chromosome 19 open reading frame 53 2 2
MIRT451622 MEIS3P1 Meis homeobox 3 pseudogene 1 2 2
MIRT451691 C1RL complement C1r subcomponent like 2 2
MIRT452090 NUCB2 nucleobindin 2 2 2
MIRT452429 QDPR quinoid dihydropteridine reductase 2 2
MIRT452941 DISC1 disrupted in schizophrenia 1 2 2
MIRT453399 RHD Rh blood group D antigen 2 6
MIRT454162 HIST1H2BK histone cluster 1 H2B family member k 2 2
MIRT454278 FXN frataxin 2 2
MIRT454537 RABL2A RAB, member of RAS oncogene family like 2A 2 2
MIRT454852 ACOT9 acyl-CoA thioesterase 9 2 4
MIRT455674 GLO1 glyoxalase I 2 2
MIRT457246 RABL2B RAB, member of RAS oncogene family like 2B 2 2
MIRT457675 ZNF587 zinc finger protein 587 2 2
MIRT457885 THEM6 thioesterase superfamily member 6 2 4
MIRT458014 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT458277 FUT10 fucosyltransferase 10 2 2
MIRT459734 RRM1 ribonucleotide reductase catalytic subunit M1 2 2
MIRT460451 NOM1 nucleolar protein with MIF4G domain 1 2 4
MIRT460498 FAM105A family with sequence similarity 105 member A 2 6
MIRT460936 NOA1 nitric oxide associated 1 2 4
MIRT461090 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT461167 SLC11A2 solute carrier family 11 member 2 2 4
MIRT461362 COL8A1 collagen type VIII alpha 1 chain 2 2
MIRT462380 YAE1D1 Yae1 domain containing 1 2 2
MIRT462778 ZNF8 zinc finger protein 8 2 2
MIRT463416 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT463660 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT464263 VCL vinculin 2 2
MIRT465128 TSC22D2 TSC22 domain family member 2 2 4
MIRT466187 TMED5 transmembrane p24 trafficking protein 5 2 4
MIRT466723 SYNJ2BP synaptojanin 2 binding protein 2 2
MIRT469100 RNF144B ring finger protein 144B 2 2
MIRT469716 RAB40C RAB40C, member RAS oncogene family 2 2
MIRT470420 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 2
MIRT470681 POLR2D RNA polymerase II subunit D 2 4
MIRT470863 PLXND1 plexin D1 2 2
MIRT471273 PGM2L1 phosphoglucomutase 2 like 1 2 2
MIRT471964 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT472674 NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 2 2
MIRT472734 MTUS1 microtubule associated scaffold protein 1 2 6
MIRT473130 MLLT10 MLLT10, histone lysine methyltransferase DOT1L cofactor 2 2
MIRT473238 SMCR7L mitochondrial elongation factor 1 1 4
MIRT473826 MAP2K7 mitogen-activated protein kinase kinase 7 2 2
MIRT473938 LYN LYN proto-oncogene, Src family tyrosine kinase 2 2
MIRT474026 LRRC20 leucine rich repeat containing 20 2 2
MIRT474503 KLHDC8B kelch domain containing 8B 2 2
MIRT474764 KIAA0930 KIAA0930 2 2
MIRT474909 KCTD21 potassium channel tetramerization domain containing 21 2 2
MIRT475329 IFNLR1 interferon lambda receptor 1 2 2
MIRT475377 ICOSLG inducible T-cell costimulator ligand 2 2
MIRT475731 HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 2 4
MIRT476546 GABPB1 GA binding protein transcription factor beta subunit 1 2 4
MIRT476979 FAM83G family with sequence similarity 83 member G 2 4
MIRT477680 EFHD2 EF-hand domain family member D2 2 2
MIRT479748 CCND1 cyclin D1 2 2
MIRT481191 ATXN7L3B ataxin 7 like 3B 2 4
MIRT481234 ATXN7L3 ataxin 7 like 3 2 2
MIRT481361 ATG9A autophagy related 9A 2 2
MIRT481386 ATG12 autophagy related 12 2 2
MIRT481650 AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 2 2
MIRT481850 AP1S1 adaptor related protein complex 1 sigma 1 subunit 2 2
MIRT482182 AHR aryl hydrocarbon receptor 2 2
MIRT482218 AHCYL2 adenosylhomocysteinase like 2 2 2
MIRT485294 PLAGL2 PLAG1 like zinc finger 2 2 2
MIRT486657 ZNF28 zinc finger protein 28 2 2
MIRT489411 TUBB2A tubulin beta 2A class IIa 2 2
MIRT491858 ZBTB5 zinc finger and BTB domain containing 5 2 8
MIRT492212 SOCS1 suppressor of cytokine signaling 1 2 2
MIRT492627 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2 2
MIRT493327 LIMD2 LIM domain containing 2 2 2
MIRT493899 FAM43A family with sequence similarity 43 member A 2 4
MIRT494261 CEP120 centrosomal protein 120 2 2
MIRT494683 ARID3A AT-rich interaction domain 3A 2 2
MIRT495966 TBC1D19 TBC1 domain family member 19 2 2
MIRT496109 SNX17 sorting nexin 17 2 2
MIRT497873 SLC12A7 solute carrier family 12 member 7 2 2
MIRT498120 PLEKHO1 pleckstrin homology domain containing O1 2 4
MIRT499403 PLCG2 phospholipase C gamma 2 2 4
MIRT499491 GGA3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 2 2
MIRT499651 SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 2 2
MIRT499940 MFSD8 major facilitator superfamily domain containing 8 2 2
MIRT499995 HIST1H2BD histone cluster 1 H2B family member d 2 4
MIRT500905 STRN striatin 2 4
MIRT501114 SLC5A6 solute carrier family 5 member 6 2 4
MIRT501177 SLC10A7 solute carrier family 10 member 7 2 6
MIRT501208 SUMO1 small ubiquitin-like modifier 1 2 2
MIRT501244 SEMA4C semaphorin 4C 2 6
MIRT501330 RNFT1 ring finger protein, transmembrane 1 2 2
MIRT501353 RNF44 ring finger protein 44 2 4
MIRT501391 RBFOX2 RNA binding protein, fox-1 homolog 2 2 10
MIRT501436 RAB11FIP4 RAB11 family interacting protein 4 2 2
MIRT501756 NSD1 nuclear receptor binding SET domain protein 1 2 2
MIRT501947 MBD2 methyl-CpG binding domain protein 2 2 8
MIRT502105 KPNA5 karyopherin subunit alpha 5 2 8
MIRT502131 KMT2D lysine methyltransferase 2D 2 4
MIRT502786 CEP135 centrosomal protein 135 2 2
MIRT502844 CELF1 CUGBP Elav-like family member 1 2 2
MIRT504787 C12orf4 chromosome 12 open reading frame 4 2 2
MIRT505021 ZNF644 zinc finger protein 644 2 2
MIRT505578 SMC1A structural maintenance of chromosomes 1A 2 6
MIRT506363 NUP155 nucleoporin 155 2 6
MIRT506934 IGDCC4 immunoglobulin superfamily DCC subclass member 4 2 6
MIRT507249 FIGN fidgetin, microtubule severing factor 2 8
MIRT507695 COIL coilin 2 6
MIRT508399 C1orf210 chromosome 1 open reading frame 210 2 6
MIRT508663 DIABLO diablo IAP-binding mitochondrial protein 2 4
MIRT508930 AK4 adenylate kinase 4 2 4
MIRT510398 ZNF566 zinc finger protein 566 2 6
MIRT510517 YOD1 YOD1 deubiquitinase 2 6
MIRT511384 IKZF3 IKAROS family zinc finger 3 2 4
MIRT512743 CD59 CD59 molecule (CD59 blood group) 2 4
MIRT515952 C9orf156 tRNA methyltransferase O 2 2
MIRT516081 ZBTB8OS zinc finger and BTB domain containing 8 opposite strand 2 4
MIRT521388 RDX radixin 2 4
MIRT522347 NCKIPSD NCK interacting protein with SH3 domain 2 4
MIRT523624 FZD9 frizzled class receptor 9 2 4
MIRT523731 FBXW2 F-box and WD repeat domain containing 2 2 4
MIRT523988 DVL3 dishevelled segment polarity protein 3 2 2
MIRT524114 DNA2 DNA replication helicase/nuclease 2 2 2
MIRT525725 SOD2 superoxide dismutase 2 2 2
MIRT527761 RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator 2 2
MIRT529725 OPRL1 opioid related nociceptin receptor 1 2 2
MIRT533186 WASL Wiskott-Aldrich syndrome like 2 6
MIRT536376 LEFTY1 left-right determination factor 1 2 2
MIRT543783 RBM12B RNA binding motif protein 12B 2 4
MIRT543866 SLC16A9 solute carrier family 16 member 9 2 2
MIRT545385 PM20D2 peptidase M20 domain containing 2 2 2
MIRT545889 ZNF200 zinc finger protein 200 2 4
MIRT546331 TGFBR3 transforming growth factor beta receptor 3 2 2
MIRT547376 MSI2 musashi RNA binding protein 2 2 2
MIRT547574 LRIG3 leucine rich repeats and immunoglobulin like domains 3 2 4
MIRT547835 IGF2BP3 insulin like growth factor 2 mRNA binding protein 3 2 4
MIRT548263 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT548349 EPHA4 EPH receptor A4 2 2
MIRT548530 DUSP1 dual specificity phosphatase 1 2 2
MIRT548558 DNAL1 dynein axonemal light chain 1 2 2
MIRT548778 COLEC12 collectin subfamily member 12 2 2
MIRT548973 CCNT2 cyclin T2 2 2
MIRT549023 CBX5 chromobox 5 2 2
MIRT549210 BEND4 BEN domain containing 4 2 4
MIRT549761 ZNF611 zinc finger protein 611 2 6
MIRT549797 KIAA0391 KIAA0391 2 2
MIRT549845 ECHDC1 ethylmalonyl-CoA decarboxylase 1 2 2
MIRT550725 PMPCA peptidase, mitochondrial processing alpha subunit 2 4
MIRT550896 ACTA1 actin, alpha 1, skeletal muscle 2 2
MIRT551281 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 6
MIRT551316 GSG2 histone H3 associated protein kinase 2 6
MIRT551930 AKAP8 A-kinase anchoring protein 8 2 4
MIRT552001 RAD18 RAD18, E3 ubiquitin protein ligase 2 2
MIRT552408 ZNF460 zinc finger protein 460 2 4
MIRT553015 USP38 ubiquitin specific peptidase 38 2 2
MIRT555548 PLEKHA3 pleckstrin homology domain containing A3 2 2
MIRT555713 PDZD8 PDZ domain containing 8 2 2
MIRT557379 HAND1 heart and neural crest derivatives expressed 1 2 2
MIRT557963 FAM222B family with sequence similarity 222 member B 2 2
MIRT559083 C19orf47 chromosome 19 open reading frame 47 2 4
MIRT559495 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2 2
MIRT561780 PEG10 paternally expressed 10 2 2
MIRT564400 EMILIN2 elastin microfibril interfacer 2 2 4
MIRT565447 SURF4 surfeit 4 2 2
MIRT566516 PARP16 poly(ADP-ribose) polymerase family member 16 2 2
MIRT567433 GNG5 G protein subunit gamma 5 2 2
MIRT567713 E2F6 E2F transcription factor 6 2 2
MIRT568659 ABHD17C abhydrolase domain containing 17C 2 2
MIRT569496 THYN1 thymocyte nuclear protein 1 2 2
MIRT573818 TGOLN2 trans-golgi network protein 2 2 2
MIRT574361 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT574745 GOLGA4 golgin A4 2 2
MIRT574784 FAM104A family with sequence similarity 104 member A 2 2
MIRT576084 Poteg POTE ankyrin domain family, member G 2 2
MIRT576809 Thbs1 thrombospondin 1 2 3
MIRT616368 RWDD1 RWD domain containing 1 2 2
MIRT617849 FMO4 flavin containing monooxygenase 4 2 2
MIRT642392 ZNF556 zinc finger protein 556 2 2
MIRT680517 PRIM2 DNA primase subunit 2 2 2
MIRT680545 ZNF584 zinc finger protein 584 2 2
MIRT680798 ZNF578 zinc finger protein 578 2 2
MIRT680836 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT681139 INTS7 integrator complex subunit 7 2 2
MIRT681269 RFC2 replication factor C subunit 2 2 2
MIRT681321 ZFAND4 zinc finger AN1-type containing 4 2 4
MIRT681357 BRI3BP BRI3 binding protein 2 2
MIRT681504 STAT2 signal transducer and activator of transcription 2 2 2
MIRT681534 ZNF738 zinc finger protein 738 2 2
MIRT681656 DTX3L deltex E3 ubiquitin ligase 3L 2 2
MIRT681736 RAB19 RAB19, member RAS oncogene family 2 4
MIRT681759 CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 2 2
MIRT681795 EIF4A3 eukaryotic translation initiation factor 4A3 2 2
MIRT681867 DNAH9 dynein axonemal heavy chain 9 2 2
MIRT681939 SLC19A3 solute carrier family 19 member 3 2 2
MIRT682100 ITGA3 integrin subunit alpha 3 2 4
MIRT682179 SLC38A7 solute carrier family 38 member 7 2 2
MIRT682236 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT682382 PHACTR4 phosphatase and actin regulator 4 2 2
MIRT682442 MTX3 metaxin 3 2 2
MIRT682602 CPA4 carboxypeptidase A4 2 2
MIRT682638 COX6B1 cytochrome c oxidase subunit 6B1 2 2
MIRT689325 FPR1 formyl peptide receptor 1 2 2
MIRT689728 ATXN2 ataxin 2 2 2
MIRT691034 ZNF799 zinc finger protein 799 2 2
MIRT691933 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 2
MIRT694882 ZNF417 zinc finger protein 417 2 2
MIRT695253 ZNF443 zinc finger protein 443 2 2
MIRT695411 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2 2
MIRT700591 PRSS22 protease, serine 22 2 2
MIRT701432 NHLRC2 NHL repeat containing 2 2 2
MIRT702482 KIAA1328 KIAA1328 2 2
MIRT702708 IPO9 importin 9 2 2
MIRT704033 EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 2 2
MIRT704421 CTPS1 CTP synthase 1 2 2
MIRT705748 AMD1 adenosylmethionine decarboxylase 1 2 2
MIRT712368 NAP1L1 nucleosome assembly protein 1 like 1 2 2
MIRT713518 PAFAH2 platelet activating factor acetylhydrolase 2 2 2
MIRT732950 HOXB1 homeobox B1 3 0
MIRT735294 MMP16 matrix metallopeptidase 16 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
let-7g Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 up-regulated
let-7g Leptin NULL NULL Quantitative real-time PCR muscles 20800581 2010 down-regulated
let-7g 17beta-estradiol (E2) approved 5757 Microarray MCF-7 breast cancer cells 19528081 2009 up-regulated
let-7g Etoposide approved 36462 Microarray Normal human fibroblasts (AG01522) 19633716 2009 up-regulated
let-7g Bisphenol A NULL 6623 Microarray immortalized cytotrophoblast cell lines 3A 20417706 2010 up-regulated
let-7g Bisphenol A NULL 6623 Microarray immortalized cytotrophoblast cell lines HTR-8 20417706 2010 up-regulated
let-7g Formaldehyde NULL 712 Microarray Human lung epithelial cells (A549) 21147603 2011 down-regulated
let-7g 5-Fluorouracil approved 3385 Microarray MCF-7 breast cancer cells 21506117 2011 down-regulated
let-7g 5-Fluorouracil approved 3385 Quantitative real-time PCR MCF-7 breast cancer cells 21506117 2011 down-regulated
let-7g Arsenic trioxide approved 14888 Quantitative real-time PCR acute promyelocytic leukemia 22072212 2012 up-regulated
let-7g 5-aza-2'-deoxycytidine (5-Aza-CdR) approved 451668 Microarray breast cancer MDA-MB231 22076154 2011 down-regulated
let-7g 5-aza-2'-deoxycytidine (5-Aza-CdR) approved 451668 Microarray breast cancer SKBR3 22076154 2011 down-regulated
let-7g Marine fungal metabolite 1386A NULL NULL Microarray MCF-7 breast cancer cells. 22159329 2012 up-regulated
let-7g 17beta-estradiol (E2) approved 5757 Microarray MCF-7 breast cancer cell line 22403704 2012 down-regulated
let-7g Bisphenol A NULL 6623 Microarray MCF-7 breast cancer cell line 22403704 2012 down-regulated
let-7g Doxorubicin approved 31703 Quantitative real-time PCR myocardial injury 22301161 2012 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-let-7g Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-let-7g Doxorubicin 31703 NSC123127 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-let-7g Verapamil 2520 NSC272366 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-let-7g Cisplatin 5460033 NSC119875 approved resistant High Tongue Squamous Cell Carcinoma cell line (Tca8113)
hsa-let-7g Doxorubicin 31703 NSC123127 approved sensitive High Leukemia cell line (K562)
hsa-let-7g 10-Hydroxycamptothecin 97226 NSC107124 resistant High Gastric Cancer cell line (BGC823, SGC-7901, MGC-803, HGC-27, NCI-N87, AGS)
hsa-let-7g Modified Allic Bfm 2002 Protocol sensitive High Childhood Acute Lymphoblastic Leukemia tissue
hsa-let-7g Fluorouracil 3385 NSC19893 approved resistant High Colon Cancer cell line (DLD-1)
hsa-let-7g Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (SKOV3)
hsa-let-7g Fluorouracil + Oxaliplatin resistant High Colorectal Cancer tissue
hsa-let-7g Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (C13*, A2780, OV2008)
hsa-let-7g Fluorouracil 3385 NSC19893 approved sensitive Low Hepatoma cell line (BEL-7402)
hsa-let-7g Cisplatin 5460033 NSC119875 approved sensitive High Ovarian Cancer cell line (COC1)
hsa-let-7g Paclitaxel 36314 NSC125973 approved sensitive High Lung Adenocarcinoma cell line (A549)
hsa-let-7g Cisplatin 5460033 NSC119875 approved sensitive Low Esophageal Cancer cell line (EC109, TE10)
hsa-let-7g Cisplatin 5460033 NSC119875 approved sensitive Low Esophageal Cancer cell line (EC109, TE10)
hsa-let-7g Cisplatin 5460033 NSC119875 approved sensitive Low Cervical Cancer tissue
hsa-let-7g Cisplatin 5460033 NSC119875 approved sensitive Low Epithelial Ovarian Cancer cell line (OVCAR3, HEY-A8)
hsa-let-7g Oxaliplatin 6857599 NSC266046 approved sensitive Low Colorectal Cancer cell line (HCT-116)
hsa-let-7g Gefitinib 123631 NSC715055 approved sensitive Low Non-Small Cell Lung Cancer cell line (PC-9)
hsa-let-7g Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-let-7g Cisplatin 5460033 NSC119875 approved sensitive cell line (CIS)
hsa-let-7g Testosterone+Letrozole resistant cell line (MCF-7)
hsa-let-7g Testosterone+Tamoxifen resistant cell line (MCF-7)
hsa-let-7g Cisplatin 5460033 NSC119875 approved resistant cell line (RPMI2650)
hsa-let-7g Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-let-7g Paclitaxel 36314 NSC125973 approved resistant cell line (SKOV3)
hsa-let-7g Pegylated interferon alpha+Ribavirin resistant tissue (chronic hepatitis C)
hsa-let-7g Cisplatin 5460033 NSC119875 approved resistant cell line (KYSE)
hsa-let-7g Paclitaxel 36314 NSC125973 approved resistant cell line (PC3PR70)
hsa-let-7g Bortezomib 387447 NSC681239 approved sensitive cell line (CCRF-CEM) (100 nM)
hsa-let-7g Bortezomib 387447 NSC681239 approved resistant cell line (CCRF-CEM) (200 nM)
hsa-let-7g Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-let-7g Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide/Methotrexate/Gemcitabine resistant cell line (Bats-72)
hsa-let-7g-5p 1h-indole-3-methanol, 1-[(4-chlorophenyl)methyl]- 11821732 NSC741909 resistant
hsa-let-7g-5p N'-(cyano(3-hydroxyphenyl)methyl)-2-hydroxybenzohydrazide 375018 NSC653844 resistant
hsa-let-7g-5p N-(5-aminopentyl)-n-(3-aminopropoxy)-2,2,5,7,8-pentamethyl-3,4-dihydrochromene-6-sulfonamide;hydrochloride 396614 NSC703117 sensitive
hsa-let-7g-5p Vfbduqdkojtrni-pknbqfbnsa-n 5468519 NSC671184 sensitive
hsa-let-7g-5p Tamoxifen 2733525 NSC180973 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-let-7g-5p Paclitaxel 36314 NSC125973 approved sensitive High Lung Adenocarcinoma cell line (A549)
hsa-let-7g-5p Platinum 23939 resistant Low Ovarian Cancer tissue
hsa-let-7g-5p Cisplatin 5460033 NSC119875 approved sensitive High Gastric Cancer cell line (SGC7901)
hsa-let-7g-5p Trametinib 11707110 NSC758246 approved resistant High Melanoma cell line (WM266) (1uM)
hsa-let-7g-5p Trametinib 11707110 NSC758246 approved resistant High Melanoma cell line (WM266) (2uM)
hsa-let-7g-5p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (WM266) (1uM)
hsa-let-7g-5p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (WM266) (2uM)
hsa-let-7g-5p Radioactivity Iodine sensitive High Papillary Thyroid Cancer tissue
hsa-let-7g-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780)
hsa-let-7g-5p Paclitaxel 36314 NSC125973 approved sensitive High Endometrial Serous Carcinoma cell line (USPC1)
hsa-let-7g-5p Temozolomide 5394 NSC362856 approved sensitive Low Glioblastoma cell line (U87, U251, HEK)
hsa-let-7g-5p Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer tissue
hsa-let-7g-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780CIS)
hsa-let-7g-5p Docetaxel 148124 NSC628503 approved sensitive High Breast Cancer cell line (MDA-MB-231, MCF-7)
hsa-let-7g-5p Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-let-7g-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-let-7g-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-let-7g-5p Palbociclib 5330286 NSC758247 approved sensitive tissue (breast cancer)
hsa-let-7g-5p Prednisone/Azathioprine/Methotrexate/Cyclophosphamide/Mycophenolate mofetil sensitive tissue (myasthenia gravis)
hsa-let-7g-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM11)
hsa-let-7g-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (BAS)
hsa-let-7g-5p Doxorubicin 31703 NSC123127 approved sensitive cell line (BAS)
hsa-let-7g-5p Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-let-7g-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-let-7g-5p Fluorouracil 3385 NSC19893 approved sensitive cell line (HCT15)
hsa-let-7g-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (MGC-803)
hsa-let-7g-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM16)
hsa-let-7g-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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