miRTarBase - #MIRT005808


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pre-miRNA Information
pre-miRNA hsa-mir-155   
Genomic Coordinates chr21: 25573980 - 25574044
Description Homo sapiens miR-155 stem-loop
Comment Human mir-155 is predicted based on homology to a cloned miR from mouse (MIR:MI0000177) .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-155-3p
Sequence 43| CUCCUACAUAUUAGCAUUAACA |64
Evidence Experimental
Experiments Cloned
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1181188719 6 dbSNP
rs759895287 7 dbSNP
rs200351615 8 dbSNP
rs377265631 10 dbSNP
rs1038360714 20 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Biomarker Information
Biomarker ID Name Type Discovered From Mode Level Source Testing Methods
BA4I1F miR-155 Safety Biomarker (SAF) Clinical/Experimental Data Expression Decrease Blood and urinary supernatants Quantitative real-time PCR
BA4I1F miR-155 Safety Biomarker (SAF) Clinical/Experimental Data Expression Increase Kidney tissue Quantitative real-time PCR
Gene Information
Gene Symbol IRAK3   
Synonyms ASRT5, IRAKM
Description interleukin 1 receptor associated kinase 3
Transcript NM_001142523   
Other Transcripts NM_007199   
Expression
Putative miRNA Targets on IRAK3
3'UTR of IRAK3
(miRNA target sites are highlighted)		 
>IRAK3|NM_001142523|3'UTR
   1 ATTCTACCAGAAGATAAAGAAAAAAGCAAGTATTGCATAGGCACCTGAGCATAGGTATGACCTTGGGAAGACATTGGCTC
  81 CATAAGCAATGCCAAGAGAATGATCAATAGTGAGTTTGGGTGATGCAGATAAACAATCTGGATAATTCCATTTCTTTTTT
 161 CCCAAACCCTCAAACAGAGTGCCTTAAAAAATTGTTTTATCAGGATAATTGTCTCATGACCAAATCCACGCTCAATTAGA
 241 GCCATTCAAAATTCCTTAAGATCATGGGTTCTGACTTCAGCCAAACAAAACAATCAAAACCTACCAAAAAGGGACTGGAT
 321 TGTAATGTCCTCTCCATCATCCTCAGTGTGAGTCCTCAGAGCCTCCATCTGCCAAGAACATTCAGTTGGATTCCATCGTT
 401 TGGTTTAGCTTGCTTGCACGGGTTGTAGGAAATGTCTAATTTGTAAATGTTAATAGATACCTTTGGAAAGAATCACCTTG
 481 TTATTCTGATTGACCCCTCTTGTTTTTTGGTTAATCCCTGACTAGCCTGCTTGTCTGAAAATGAGCCAGGTTCACCCTTA
 561 GCTACGGCATGCTCTGGGTTGAAAGGGGATTTCTTCCCAAGATCTATCCTAAACTCTTAGGACAGTTTATCCTGTATTGA
 641 CTATTATTACAGCTTTTTAAAAACAGACTTAGTGACCTATTATATCTTAAGGAGACTATGTGAAATGTCCATCAAGTAAT
 721 TTTTATTCCTGAGAAAATGGCTGGTCAAGGGCCTAGGTCAGCTTTTTGTTTAATCTACACCTTTCAACTCTGGGCCTTCA
 801 TTCCTGCTGTTTCTTGGATCTCCCTCTTTTGAAATCCTACCAATCATCAGAGCTCTACAAAACAGCCACCTCCTGGAAGC
 881 TTCCCTAATCTCTACAACCAGAAGTACTCCCTTTATCAGTATTTCCACAGCAATTTCTTTGTATTTCTATTTTATATTTA
 961 TCACTTTCTGAATTATATCAAAGCTGCTTGTCTTATCTCTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCATCCAGGCT
1041 GGAGTGCAGTGGCACAATCTCGGCTCACCGCAAGGTCTGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAG
1121 TAAAGGTGGGACTACAGGCGCCCGCCACTACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTT
1201 AGGCAGGATGGTCTCGATCTCCTGACCTCATGATCCGCCTGCCTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCA
1281 CCGCGCCCAGCCTTCATCTCTTTTACTAGGTTGTAAACTCCCTATATTAGTTTTCTATTGTTTTTGTAACACATTATCAC
1361 AAATTTAGTGACTTAAAGTAACATAAATTAATTATTTTGCAGTTCTGGAGGTCAGAATTCCTTAGCATTCTTTCTGGAGG
1441 CTGTTGGGGAGAACTCACTGCCTTGCCTTTTCCAGCTTCTAGAGGCCACCTGCCTTCTTTGGCTCATGGCCTCTTCCTCC
1521 GTCTTCAAAGCCAGCAACGTGACATTTCAGATCTCCCTCTCTCTGTCTGTCTCACCGCATCTCTTCACTACCCTCTTCCT
1601 CTCATTCTGGCCCTTCTGCATGTCTTTTATAAAGACCTTTGTGATTTCACTGGGCCCACTCATATAAGCCAGGAAAATCT
1681 CTGTGTCTCAGATCCTTAATTTAATTACACCTGCAAAGTCCGTTTTCTCGTGTAAAGTAACATATTCACAGGTTTCTGGA
1761 ATTGGGACGTGGACATCTTCGGGGGACCATTACTCTGTCTGTCATACTCCCTGAGTGTGTAAGGGCCATCTCTTCAGAGC
1841 CTAATGTGTCATCCTACACAGAGCAGGTGTTTCCTTATAAATTAAGTTGAATTAAATTACCCCTATGAAGCCACATAATC
1921 AATAATTCAGCTATAATAAACATTGCCGAATAAATTAACAAAGGGAGGATAATGACTCCTTATGATGATGGATAGAAACA
2001 CTGAAGAAAACCATTTTCAGAGGATTTACTGAATTTTCCTCTCCAAGGAGCTTGTAATAGAAGGGTAAACCTCTAGTTTC
2081 TTGTCCAGCAGAGGAATAGGCTCATGTCTTTTGTTTTATTTTATTTTTTTGGTGAGTCAGTATGGTTGGGTTAATCATAT
2161 TCACATTAGATTCCATGTTGAAGAACAACTAATCAAAGAAGAAAATCATCAGGAATCAGGGTGAGATTAACAGACCAAGG
2241 TCAGAAACATGGAGTTACAATTTTCCAAAAAAGCACGAAGTGAGATTAAAACCACAGTAAGTCTTAGTCTGACTGACAGG
2321 CTTTATACAGGCCCTCGGTAAGCAGTTGGGAGAACCCATGCCCACCACTGCTCTGTACGGTATCTGGCTGCTCAGAGCTC
2401 TCTGATTCACAAAAGAGATCATCAAGAATTGACTCTGTGTTAAACTGTTTTTCACTTAGAATATGGACCCCCACCAATAC
2481 ATTCAATGAAGGGTCATTAAGGAAGCTCTGATTAACACCAGGCCCATGCAGTTACTCCGCACATATAATCTGTGGGTATT
2561 ATGTTGATTTGAACTTGCTTAGCTGACTTAAAGCAGGGTTTCTCAAACTGTAGTATGCATCAGAATGACTTGGAAAGCTG
2641 GTTAAAAACGCAGATTGCTGGGTCCACCCAGCTTCTGATGCAATAGGTCTGGGGTTAGAAATTTTGCTTTCTAATGAGTT
2721 CCCAGGTGATGCTGATGCCAATGATGTGAAGCCCGCTCTTCACATCCGTGAAAATCGCTGCCTTAAGGTGCTCTTAAATT
2801 GTTATAGATTGGTAGATCCTACCTTTCCATCACTGGTATGTTTTTTGAGAAAAGGATCCTTTCTTTTCATTCTGTTATAT
2881 TCATCCTATTACATAGGATGTTGGTTAGCACAGAGTGGGAGCTCTAGAAAGATTGTTGACCAATCATCTTATTGACTAGA
2961 CCATCTTTCTAGAGTATAACTATTTTGGACACCTCAAAGATGAAGTCAGATAAGCTGGCAGTGACCTGATTAACGTTGTG
3041 GTAAGCAGATGCCACTGTGGCTGGGAAGTACCAAATCTTCTGTTGAGTGATTCAGTCTTCCTGACTAGATTTGCCTTCTA
3121 GTGGGTGTATTAATAAGCGTTAGTTGATATGAATTAAATGTTGCAACTTTCTATGGGTAATAAGAGGATACCTTTATAGT
3201 TTCATGATGTGGAGACCAAGATACATAAGAAAGCAAGAATGAGTCTCCGGGTGTTCCCTCTGATCAGCAAACATGAATTC
3281 ATAATTTCATTTACTCTCATTTTTGTAATGCACTCTGAGCAATCCTCCAGGCAGATCCTATTTACTAAGCTTCAGGCTTT
3361 TGTCCCATTTTATAATGCCCAAACACATGGAGAAAACATTTTGTTGTTTTTAAAAACAGGTATGGGATTTCTGATATAAT
3441 CAATTTTATTGACTTCTTGGGAGTTGTAATGATCTGTGACTCACTGCATAATATTGTAGTTTTATAGGGTGGCACATCAC
3521 CCTGTGTAAAACAACTTTAATGACCTGAGGACTGATGAGTACAGGAAGTGAGGTTTATCATGAGTAGCATTTATTAAGCA
3601 TCTGCTAGAATCAAAGCACTGCATTAGCTACTAAGGTACAAAGTAAGACACAGTTTAATAAGGAAGACAGGGCATCTACC
3681 CAAGTCAACAGTTCAGTGACATCTGTTATTTGAACCACACACCAATGCAACCGAAGTAAATGCTGAAAGGGTGAGAAGAA
3761 GGAATAGATTACTATGCATTTTTGAGAGGATGAAGAAGGCTTCTTGGAGAAGGTTTCTGAAAAGAGATACGGAATTAAGA
3841 GAAATAGAAAAGAGCACTGACGAAGCACTCAGGATGGCTATTCAAGGAATTGGGGATCCACAGCAGCTGTGCACAACCAT
3921 CCCTAATGCCAGAAAAATGGGGTAAGGGTGAAGGGAACTGGGTCTAGAGCTTTGCATGTTTTTTTCTGGTTAACCCTTAG
4001 AGTCACCCTGAAGGTGTGGATCCCATCTTATAATAAGGTGAGGACACTGAGTCAGGAAACTAACTTGCTAAAATCAAGTC
4081 CTCCCAGTCCTCCCATCAGGTCCTTCCAGATCTGGAGGAGCCAGGATTTGAACTCACATTTGTCTGACTTCAAAATCCAT
4161 GCTTTTTCTTGTGTTCCAAATTGCACAATGGAGTCACTGCCAGTTCAAGCTCCTATGAAAAGGGATGGATGTGAAAAGTC
4241 ATTTGTTGATTCCACAGATTTTTAGTAGGTACCATGTCTCCTGCCTTTATCACTATCCTACTCCTCTGCTACAACTTCTC
4321 TGCTACAGGCACCCACTGCAGTTACTTGATATGAGTTAAATGAATCCATCCATCCAAACTTCCATTCATTGAATAAATAC
4401 TTAGCAATGGCTTCCTTTGTATCAGGCACTATTCTAGGAGCTGGGGCTACAGTGCAGATGGAAACCAGCAAAGCTCACTG
4481 CCCTCATGGAGCTTATATGTAAGTGAATAAATCTCAGGGTGGTTCTCCTGTCATAGGTCCTGGCTCCTCTGCCAGCTCTT
4561 CCAAATGGGTTCAGAGAGGTTTTCTCCTTGTCCTGTTGTGTAACTGATAATCCCATGGTGGACCTCACTTTGCTATTCAT
4641 ATGCACTAAGTAGTTTATGGTGTGCTTTGTGGCTGGCAATTGTGACAGATTCTATTCTTCTATTGGTATGTGGTTTCTTT
4721 GGGGCATTTGTTTGGATACTGATGGCATCTTCCGGGGGTCTGAGGCACCTACACAAACCTCAGGTCACTATCACGTGATA
4801 CTGGAGTTGCCTGTTAAATTATATTTCTTCTTCCACAAAACTGCAGGTTCCCTGAGGGAAAGGTCTATGTCCTGCTCATT
4881 TTTGGATCCCTAATGGCTGGCACAGTACCTGGTGCATAATATGGTTCAACAAATATTTGTAAAATGAATGAATCAAATAG
4961 TCCTTCAAAGCATCTTCAGAATCAAGATTGTCATCTAGATTGCACCCGAAGTTTATCTTTCTAGTATTCAGAATATAATC
5041 AATCATTGCTTAAATTATTCCATTTCATCATTCTTGAATAAAAGCTACTAATTTTAAATACTAATATCTGAGATATCTTC
5121 GAAAAGAAGATTAGTCGTTGTATGTGTTGCTTATAAATTTTCTCTATGGTGGAAAATATTCCCAAACCATGTCTAAGCAA
5201 TGAAAAACCAGTGTTCTGGCAGGAAATAAACTGATGTTTGTTGTGTTTTGTATCTGTCTTCCCGTTCCAAATCATTTATA
5281 TATACTTGATGGTCTGTGGGCTTGACTTGCAAGTATTTTCCTGGGAGACATTTTTATTCAAAAGACCTGTATTGCCTGCC
5361 AAACCTTCATTTAAGAGACTCATTATGGATGTCATCTGCATCATTGCAAACTTTTCTGGTCGTCTCTATAAATAGCAAGA
5441 TAATATTTACAGAGTTTTACATTGGCTCTTGAATTTTAAAATATTCTTATAGACAAACATTAATTGGAATGGGGGGTAAG
5521 GAGGTAGGAATGGCTTACTTGCGGAAATGCAGGCTCATTGTTGTGTCTAGTAGGTGCTAGGTGCATTCACACATCTCTTA
5601 AGCTTTAAACAACCTATTGAGCCGGTTTCCATTTCCTTGATCTATTAGATTTAAAAAAATGAAGCATAAAGGAGTTGGCT
5681 CTTGCCCTAAGTCATACTACTGATGGAATGAGAATACAAACCAAAAACACTTTATTCAAGTCCAGGAAATATCTGCCTTG
5761 AAAAAGAATAACTTAAAAATTAAAAGTGTCCTCTATTTGAACATGAAAACAGCTAATAAAGATGTGTTATTTTATTTTAT
5841 TATTATTAATTTTGTCCTCCCATATTGGCAAAGATAAAGCAATTGACAAAAATGGAATTCTTGTTCAATACTGGCAGGAG
5921 TGAAAATTGGTAGAACCTTTCTAGAAGGCAATTTGGCAACATGTATGAAAACCTAAATGTTGATACACCTTTACCCAGCA
6001 GTTTGTTTAGGAATTTATCCTAATGAATAAAAGTTGTCCAAGTCTTCAAACATGAGCCCAAAGGTATATTTCATGATGTT
6081 TATGATATTAAAACATTGGAAACAACTGAAACATCCTTCAGTAAAAGATGGATTAAATAAATTCCATGCAGTTGTCATTT
6161 AAAAATATTTAGATATATGTTTATTGCTATGGATATATGTTCCCAAAATATTATTGAATCAAAAAGTAGACTACAGGATA
6241 TATGTTGAATATGAGCTCATTTATAACATTGAATATTTTAAGATAATGTATGTTTCATAGAGAGATCTTCACCAAATGTT
6321 AAGGATTTTTTTTTCTGGGCTGTGGTATTTGGGTGATCTTTACATTCTTCAGACTCATGTGTGTTTGAAACTTTTTATAA
6401 TGAACATATATCATTTTTATTAGAAAAGAATAAAGTTTTTGAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' acAAUU--ACGAUUAU-----ACAUCCUc 5'
            |||:  |||| : |     ||||||| 
Target 5' gtTTAGCTTGCTTGCACGGGTTGTAGGAa 3'
 403 - 431 150.00 -9.10
2 
miRNA  3' acAAUUACG-AUUAU-ACAUCcuc 5'
            | | ||| ||||| |||||   
Target 5' acTCACTGCATAATATTGTAGttt 3'
 3479 - 3502 128.00 -6.72
3 
miRNA  3' acAAUUA--CG-----AUUAUACAUCCuc 5'
            ||| |  ||     |||| |||:||  
Target 5' agTTACTCCGCACATATAATCTGTGGGta 3'
 2530 - 2558 122.00 -8.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM1363682 1 COSMIC
COSN31525487 5 COSMIC
COSN30185608 21 COSMIC
COSN30136158 31 COSMIC
COSN30471785 59 COSMIC
COSN30113204 78 COSMIC
COSN30178583 82 COSMIC
COSN30511602 82 COSMIC
COSN30514677 118 COSMIC
COSN30102297 142 COSMIC
COSN30146879 172 COSMIC
COSN24968004 231 COSMIC
COSN9754060 403 COSMIC
COSN23221952 954 COSMIC
COSN4730997 997 COSMIC
COSN26194564 1063 COSMIC
COSN9568215 1253 COSMIC
COSN20473637 1582 COSMIC
COSN1581362 1847 COSMIC
COSN23066705 1942 COSMIC
COSN29001568 2170 COSMIC
COSN1581363 2220 COSMIC
COSN26217615 2610 COSMIC
COSN5326096 3368 COSMIC
COSN23858009 3551 COSMIC
COSN9568216 3903 COSMIC
COSN32137818 3980 COSMIC
COSN5950151 4273 COSMIC
COSN24862789 4760 COSMIC
COSN4703525 4855 COSMIC
COSN5950152 5000 COSMIC
COSN4703526 5203 COSMIC
COSN4730998 5625 COSMIC
COSN17287873 5658 COSMIC
COSN7618395 5693 COSMIC
COSN1151000 5746 COSMIC
COSN16418858 5797 COSMIC
COSN16811218 5821 COSMIC
COSN9568217 5942 COSMIC
COSN2481295 5973 COSMIC
COSN1581364 6089 COSMIC
COSN9084123 6293 COSMIC
COSN1581365 6396 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs754861149 5 dbSNP
rs781139086 9 dbSNP
rs747906482 10 dbSNP
rs755951556 11 dbSNP
rs1217050969 16 dbSNP
rs7135413 25 dbSNP
rs749537577 27 dbSNP
rs541950313 37 dbSNP
rs778798204 38 dbSNP
rs745978500 42 dbSNP
rs190307343 45 dbSNP
rs1269621896 50 dbSNP
rs976395494 51 dbSNP
rs772663185 52 dbSNP
rs1266482301 53 dbSNP
rs1238019569 62 dbSNP
rs1349707716 70 dbSNP
rs984619333 75 dbSNP
rs1479102951 76 dbSNP
rs1014790297 77 dbSNP
rs1358398499 81 dbSNP
rs1193567002 94 dbSNP
rs1480836579 99 dbSNP
rs1399572640 108 dbSNP
rs1269525666 115 dbSNP
rs1313743422 118 dbSNP
rs945783538 120 dbSNP
rs1208324616 126 dbSNP
rs79110985 132 dbSNP
rs543849745 137 dbSNP
rs564040733 147 dbSNP
rs1198976451 149 dbSNP
rs937171870 150 dbSNP
rs1276304670 151 dbSNP
rs1055697068 155 dbSNP
rs895740996 164 dbSNP
rs1302727784 169 dbSNP
rs1384751667 171 dbSNP
rs577491389 175 dbSNP
rs1299115728 177 dbSNP
rs1046824749 183 dbSNP
rs1398537173 184 dbSNP
rs879047011 194 dbSNP
rs781545982 203 dbSNP
rs931602391 230 dbSNP
rs1215376814 231 dbSNP
rs546434554 234 dbSNP
rs1379473929 236 dbSNP
rs897195820 239 dbSNP
rs559521007 248 dbSNP
rs914821195 250 dbSNP
rs528657105 256 dbSNP
rs1180740907 269 dbSNP
rs1458971148 270 dbSNP
rs1184853688 271 dbSNP
rs1236830722 275 dbSNP
rs947660877 279 dbSNP
rs548313832 281 dbSNP
rs1041853849 296 dbSNP
rs114967671 297 dbSNP
rs1230366602 299 dbSNP
rs1330156631 302 dbSNP
rs530962084 308 dbSNP
rs1448502245 312 dbSNP
rs1057452554 314 dbSNP
rs1007013596 325 dbSNP
rs1331047305 332 dbSNP
rs1397145310 335 dbSNP
rs77221348 349 dbSNP
rs373139482 351 dbSNP
rs1170897660 352 dbSNP
rs570789637 368 dbSNP
rs755555896 375 dbSNP
rs1364444359 377 dbSNP
rs777514168 379 dbSNP
rs1236168874 380 dbSNP
rs1394347684 390 dbSNP
rs887675998 394 dbSNP
rs541571803 396 dbSNP
rs748884885 398 dbSNP
rs1198661052 399 dbSNP
rs1286066988 404 dbSNP
rs978889965 404 dbSNP
rs1014857350 413 dbSNP
rs1350984272 414 dbSNP
rs925744463 418 dbSNP
rs182531161 420 dbSNP
rs991331280 421 dbSNP
rs917123193 426 dbSNP
rs975945453 433 dbSNP
rs1361294360 442 dbSNP
rs185335126 455 dbSNP
rs949948170 462 dbSNP
rs11465989 473 dbSNP
rs1157788559 479 dbSNP
rs985759592 481 dbSNP
rs914265514 484 dbSNP
rs968366334 495 dbSNP
rs548994592 503 dbSNP
rs897118102 517 dbSNP
rs1235526773 518 dbSNP
rs11465990 526 dbSNP
rs1263294690 527 dbSNP
rs1218092325 538 dbSNP
rs1487106603 539 dbSNP
rs1284950280 557 dbSNP
rs1228521765 558 dbSNP
rs1048917012 566 dbSNP
rs1346767430 568 dbSNP
rs1282755751 570 dbSNP
rs1244743856 575 dbSNP
rs924889765 586 dbSNP
rs888537923 592 dbSNP
rs1280191870 599 dbSNP
rs555536889 603 dbSNP
rs1198377490 607 dbSNP
rs1006963060 609 dbSNP
rs1359980367 618 dbSNP
rs1277224200 621 dbSNP
rs1407258856 633 dbSNP
rs1392649979 634 dbSNP
rs1457841465 639 dbSNP
rs1474845832 644 dbSNP
rs1180392476 658 dbSNP
rs1195744915 659 dbSNP
rs1476587821 667 dbSNP
rs938813497 678 dbSNP
rs1039844514 681 dbSNP
rs1057334082 683 dbSNP
rs1438831249 688 dbSNP
rs901373675 695 dbSNP
rs998831803 699 dbSNP
rs1288197966 702 dbSNP
rs1319220446 703 dbSNP
rs915978703 704 dbSNP
rs948806367 711 dbSNP
rs1217325802 712 dbSNP
rs1048412848 716 dbSNP
rs1275466583 719 dbSNP
rs1438902424 720 dbSNP
rs1464670470 721 dbSNP
rs1329499778 722 dbSNP
rs772091770 726 dbSNP
rs1460786944 732 dbSNP
rs1397239208 736 dbSNP
rs1400742523 738 dbSNP
rs1007778452 746 dbSNP
rs888420090 780 dbSNP
rs1467275549 792 dbSNP
rs1463973793 794 dbSNP
rs1020549452 797 dbSNP
rs967425596 800 dbSNP
rs1376874437 801 dbSNP
rs1004235633 807 dbSNP
rs1442095836 808 dbSNP
rs1478814722 815 dbSNP
rs1244557281 820 dbSNP
rs1192616590 827 dbSNP
rs1303778274 830 dbSNP
rs999868295 834 dbSNP
rs1230554492 843 dbSNP
rs575390186 844 dbSNP
rs1036650412 846 dbSNP
rs1317963626 849 dbSNP
rs1200039561 856 dbSNP
rs1317788964 860 dbSNP
rs897751363 864 dbSNP
rs189846286 868 dbSNP
rs1220950223 869 dbSNP
rs1342955162 873 dbSNP
rs184072059 880 dbSNP
rs1210360160 882 dbSNP
rs997753380 891 dbSNP
rs1447767103 895 dbSNP
rs1269125983 896 dbSNP
rs1030206012 899 dbSNP
rs1333072871 901 dbSNP
rs1444505088 905 dbSNP
rs879061844 911 dbSNP
rs917071171 916 dbSNP
rs953116914 941 dbSNP
rs1478830717 944 dbSNP
rs1168692781 987 dbSNP
rs1007232960 995 dbSNP
rs73127474 997 dbSNP
rs919182493 998 dbSNP
rs1438426459 1000 dbSNP
rs1491550362 1000 dbSNP
rs370945705 1000 dbSNP
rs754028210 1000 dbSNP
rs1491218739 1001 dbSNP
rs80035682 1011 dbSNP
rs1462372162 1012 dbSNP
rs1356062556 1016 dbSNP
rs551521714 1017 dbSNP
rs1388978187 1018 dbSNP
rs1048382217 1021 dbSNP
rs1303419428 1024 dbSNP
rs143962121 1024 dbSNP
rs968314210 1025 dbSNP
rs1340811388 1027 dbSNP
rs1419940102 1028 dbSNP
rs80070238 1034 dbSNP
rs559606920 1038 dbSNP
rs942769578 1041 dbSNP
rs977121107 1048 dbSNP
rs1418918875 1049 dbSNP
rs1414948401 1059 dbSNP
rs148647533 1060 dbSNP
rs1316762951 1062 dbSNP
rs1245362300 1063 dbSNP
rs960357564 1070 dbSNP
rs1267178376 1071 dbSNP
rs1456973970 1072 dbSNP
rs1489397019 1076 dbSNP
rs993387654 1084 dbSNP
rs1209070648 1085 dbSNP
rs1316177794 1086 dbSNP
rs189000081 1086 dbSNP
rs948879637 1094 dbSNP
rs1048485565 1095 dbSNP
rs909971582 1101 dbSNP
rs1489355296 1105 dbSNP
rs903445464 1113 dbSNP
rs1292135459 1116 dbSNP
rs939970562 1118 dbSNP
rs11613359 1119 dbSNP
rs1296013629 1128 dbSNP
rs897735558 1129 dbSNP
rs1350864063 1131 dbSNP
rs1422949616 1135 dbSNP
rs549672330 1139 dbSNP
rs1032678558 1140 dbSNP
rs1195031948 1141 dbSNP
rs1478878334 1142 dbSNP
rs1261098374 1144 dbSNP
rs1186192673 1145 dbSNP
rs553497484 1151 dbSNP
rs1488909076 1153 dbSNP
rs1265820810 1154 dbSNP
rs1167492527 1155 dbSNP
rs561918102 1156 dbSNP
rs1272530167 1157 dbSNP
rs1457711316 1160 dbSNP
rs1299268409 1162 dbSNP
rs1292769716 1171 dbSNP
rs1381322337 1176 dbSNP
rs1362846607 1178 dbSNP
rs530924630 1185 dbSNP
rs1024076751 1186 dbSNP
rs142687190 1188 dbSNP
rs1007348877 1189 dbSNP
rs1433983453 1197 dbSNP
rs1269816778 1204 dbSNP
rs1021294389 1207 dbSNP
rs1252112847 1216 dbSNP
rs919117695 1216 dbSNP
rs12822383 1217 dbSNP
rs998923394 1218 dbSNP
rs77111803 1220 dbSNP
rs1312262698 1222 dbSNP
rs546956726 1227 dbSNP
rs192954453 1237 dbSNP
rs1023241664 1238 dbSNP
rs752326687 1249 dbSNP
rs1332418944 1258 dbSNP
rs183752554 1271 dbSNP
rs984297836 1273 dbSNP
rs576646936 1274 dbSNP
rs1466664790 1278 dbSNP
rs1379420721 1282 dbSNP
rs371467551 1282 dbSNP
rs539152739 1282 dbSNP
rs1483608087 1283 dbSNP
rs774763846 1284 dbSNP
rs1041884057 1285 dbSNP
rs187246519 1286 dbSNP
rs922658818 1287 dbSNP
rs549223791 1290 dbSNP
rs569001192 1292 dbSNP
rs537544851 1293 dbSNP
rs936250617 1297 dbSNP
rs1231668586 1299 dbSNP
rs1346648890 1300 dbSNP
rs1382505881 1301 dbSNP
rs1242849805 1318 dbSNP
rs1418291864 1319 dbSNP
rs889037822 1325 dbSNP
rs759788177 1330 dbSNP
rs1054742504 1339 dbSNP
rs1042909431 1347 dbSNP
rs1434352123 1350 dbSNP
rs545391943 1352 dbSNP
rs1361336453 1353 dbSNP
rs1160677362 1358 dbSNP
rs1156428906 1365 dbSNP
rs1441376993 1402 dbSNP
rs1344291380 1421 dbSNP
rs1181050726 1429 dbSNP
rs768117268 1437 dbSNP
rs1424287669 1441 dbSNP
rs1448107964 1443 dbSNP
rs1208032777 1448 dbSNP
rs557827677 1449 dbSNP
rs1304146203 1452 dbSNP
rs753094657 1457 dbSNP
rs1286354693 1471 dbSNP
rs998644232 1474 dbSNP
rs894120387 1493 dbSNP
rs1349033468 1507 dbSNP
rs1309922302 1512 dbSNP
rs1279294968 1516 dbSNP
rs1012588417 1517 dbSNP
rs1342725138 1521 dbSNP
rs1031851158 1522 dbSNP
rs577604429 1524 dbSNP
rs1361230821 1535 dbSNP
rs191708369 1539 dbSNP
rs1285560180 1540 dbSNP
rs993691465 1543 dbSNP
rs1370185938 1544 dbSNP
rs758044916 1552 dbSNP
rs1185690211 1554 dbSNP
rs1474620929 1556 dbSNP
rs77530321 1557 dbSNP
rs1195429281 1568 dbSNP
rs746563941 1569 dbSNP
rs1254271624 1576 dbSNP
rs970333654 1577 dbSNP
rs573221061 1578 dbSNP
rs34594620 1580 dbSNP
rs369954307 1580 dbSNP
rs397850898 1580 dbSNP
rs200087870 1581 dbSNP
rs147522004 1582 dbSNP
rs149763274 1584 dbSNP
rs1358892837 1592 dbSNP
rs542083974 1593 dbSNP
rs1233175898 1594 dbSNP
rs73327350 1599 dbSNP
rs781629990 1602 dbSNP
rs746392004 1609 dbSNP
rs770133699 1611 dbSNP
rs1406787011 1612 dbSNP
rs74802631 1614 dbSNP
rs1326004846 1618 dbSNP
rs922678991 1622 dbSNP
rs933970557 1630 dbSNP
rs924793124 1637 dbSNP
rs1460815462 1643 dbSNP
rs1423759760 1649 dbSNP
rs936170422 1654 dbSNP
rs1474230464 1656 dbSNP
rs763219584 1663 dbSNP
rs1054671579 1671 dbSNP
rs1199126567 1674 dbSNP
rs1453725625 1677 dbSNP
rs1251497705 1678 dbSNP
rs1402443874 1678 dbSNP
rs1319160651 1682 dbSNP
rs894736574 1684 dbSNP
rs150970923 1686 dbSNP
rs1275710442 1694 dbSNP
rs1338826083 1694 dbSNP
rs1438852152 1699 dbSNP
rs564597153 1708 dbSNP
rs906885941 1711 dbSNP
rs1221110088 1714 dbSNP
rs1400869232 1715 dbSNP
rs753385801 1719 dbSNP
rs993248196 1723 dbSNP
rs183809844 1730 dbSNP
rs887595053 1731 dbSNP
rs904331685 1734 dbSNP
rs934492086 1743 dbSNP
rs1199405954 1748 dbSNP
rs1260539492 1750 dbSNP
rs1456876521 1751 dbSNP
rs1198577196 1752 dbSNP
rs1193319436 1762 dbSNP
rs757039156 1769 dbSNP
rs895567296 1770 dbSNP
rs1235153470 1773 dbSNP
rs540612726 1781 dbSNP
rs1192536839 1782 dbSNP
rs1017442047 1783 dbSNP
rs1279367601 1794 dbSNP
rs1422678991 1798 dbSNP
rs1022659263 1805 dbSNP
rs560483814 1808 dbSNP
rs541530917 1811 dbSNP
rs1300999949 1820 dbSNP
rs1233369939 1823 dbSNP
rs1377358722 1834 dbSNP
rs1401846359 1836 dbSNP
rs1463942793 1840 dbSNP
rs955589993 1844 dbSNP
rs1353436764 1845 dbSNP
rs977507471 1846 dbSNP
rs1005839247 1847 dbSNP
rs1438398318 1859 dbSNP
rs778680836 1862 dbSNP
rs1291981934 1873 dbSNP
rs924690572 1877 dbSNP
rs936117990 1879 dbSNP
rs1440746098 1882 dbSNP
rs1410595722 1884 dbSNP
rs990307348 1890 dbSNP
rs1280102209 1891 dbSNP
rs1017203777 1895 dbSNP
rs1316158391 1902 dbSNP
rs916119774 1904 dbSNP
rs1291272540 1906 dbSNP
rs961546329 1907 dbSNP
rs994759477 1915 dbSNP
rs538854585 1916 dbSNP
rs1213043947 1920 dbSNP
rs1484724867 1921 dbSNP
rs1244614759 1923 dbSNP
rs955668184 1924 dbSNP
rs112606488 1928 dbSNP
rs569001546 1932 dbSNP
rs1286024495 1940 dbSNP
rs745729365 1944 dbSNP
rs978609834 1948 dbSNP
rs1284287719 1949 dbSNP
rs1425084945 1951 dbSNP
rs1416147836 1956 dbSNP
rs760087181 1962 dbSNP
rs925879970 1968 dbSNP
rs1047434701 1984 dbSNP
rs1167233656 1990 dbSNP
rs1157295792 1994 dbSNP
rs887532676 2001 dbSNP
rs934481959 2004 dbSNP
rs531520828 2010 dbSNP
rs758081966 2014 dbSNP
rs1005960637 2015 dbSNP
rs1038841789 2020 dbSNP
rs1364741595 2025 dbSNP
rs1474290441 2030 dbSNP
rs900369245 2034 dbSNP
rs1168288 2036 dbSNP
rs866572676 2039 dbSNP
rs1216641147 2040 dbSNP
rs1030678536 2042 dbSNP
rs916986150 2051 dbSNP
rs1285286182 2062 dbSNP
rs999266911 2064 dbSNP
rs949819160 2074 dbSNP
rs1235023522 2076 dbSNP
rs1332063722 2081 dbSNP
rs561405126 2094 dbSNP
rs1359153826 2097 dbSNP
rs571297125 2098 dbSNP
rs957437248 2102 dbSNP
rs540660007 2113 dbSNP
rs990256458 2118 dbSNP
rs1286744923 2121 dbSNP
rs1430547042 2123 dbSNP
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rs970227325 2124 dbSNP
rs1291419350 2138 dbSNP
rs1460292378 2145 dbSNP
rs188336372 2146 dbSNP
rs959201864 2157 dbSNP
rs10506481 2161 dbSNP
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rs1216840093 2175 dbSNP
rs1259980559 2176 dbSNP
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rs1005243082 2178 dbSNP
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rs1253592099 3214 dbSNP
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rs779654004 3341 dbSNP
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rs547132538 3355 dbSNP
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rs1245064764 4000 dbSNP
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rs1002403958 4415 dbSNP
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rs1444125225 5273 dbSNP
rs1276414453 5275 dbSNP
rs1042146274 5276 dbSNP
rs906159170 5281 dbSNP
rs574618581 5285 dbSNP
rs1401447365 5288 dbSNP
rs938306691 5290 dbSNP
rs1056517630 5291 dbSNP
rs917630573 5295 dbSNP
rs543227387 5299 dbSNP
rs1339293562 5301 dbSNP
rs1055354570 5308 dbSNP
rs1330460413 5313 dbSNP
rs1333690519 5328 dbSNP
rs1390876412 5331 dbSNP
rs1441034452 5333 dbSNP
rs1400285297 5341 dbSNP
rs1414783815 5345 dbSNP
rs1283306518 5349 dbSNP
rs1325109431 5352 dbSNP
rs1473639785 5356 dbSNP
rs1241257240 5365 dbSNP
rs748394229 5366 dbSNP
rs772211082 5368 dbSNP
rs895426964 5375 dbSNP
rs1182864513 5382 dbSNP
rs762491192 5387 dbSNP
rs1464979387 5401 dbSNP
rs557088552 5404 dbSNP
rs994996503 5405 dbSNP
rs1221578978 5410 dbSNP
rs576879388 5412 dbSNP
rs898294872 5422 dbSNP
rs146789934 5423 dbSNP
rs1264644081 5424 dbSNP
rs1290141139 5429 dbSNP
rs538185441 5434 dbSNP
rs1005338427 5435 dbSNP
rs1197402266 5439 dbSNP
rs765995634 5442 dbSNP
rs1314994426 5458 dbSNP
rs559393069 5462 dbSNP
rs1049602782 5466 dbSNP
rs751173541 5468 dbSNP
rs974744381 5475 dbSNP
rs889686745 5482 dbSNP
rs1008168077 5490 dbSNP
rs1167154859 5494 dbSNP
rs1406904490 5495 dbSNP
rs1248151630 5497 dbSNP
rs1019358796 5499 dbSNP
rs1028177870 5508 dbSNP
rs1184324949 5511 dbSNP
rs901853926 5511 dbSNP
rs1485240945 5514 dbSNP
rs541596001 5515 dbSNP
rs1246974602 5517 dbSNP
rs1488348019 5520 dbSNP
rs375097876 5524 dbSNP
rs954139785 5536 dbSNP
rs1271094312 5537 dbSNP
rs989320233 5543 dbSNP
rs1021070531 5544 dbSNP
rs528088886 5548 dbSNP
rs968181211 5551 dbSNP
rs1192391268 5552 dbSNP
rs1229583151 5553 dbSNP
rs1425051801 5554 dbSNP
rs1214114096 5555 dbSNP
rs915023222 5557 dbSNP
rs979584773 5557 dbSNP
rs1434492594 5558 dbSNP
rs1363498251 5561 dbSNP
rs1302371580 5563 dbSNP
rs945232515 5565 dbSNP
rs773492139 5571 dbSNP
rs1391990574 5575 dbSNP
rs1168202552 5577 dbSNP
rs555202201 5582 dbSNP
rs1408963135 5583 dbSNP
rs927709079 5584 dbSNP
rs767232621 5594 dbSNP
rs938984505 5617 dbSNP
rs561407629 5624 dbSNP
rs577578480 5625 dbSNP
rs1303423707 5626 dbSNP
rs550130611 5631 dbSNP
rs895395591 5632 dbSNP
rs140692704 5633 dbSNP
rs919689359 5650 dbSNP
rs931092113 5650 dbSNP
rs200709557 5652 dbSNP
rs1058222 5653 dbSNP
rs543588682 5653 dbSNP
rs78816928 5653 dbSNP
rs889664441 5653 dbSNP
rs115134383 5654 dbSNP
rs1182393241 5659 dbSNP
rs1223468805 5666 dbSNP
rs1177145849 5669 dbSNP
rs777736900 5671 dbSNP
rs1258278581 5675 dbSNP
rs1018972161 5680 dbSNP
rs565784981 5681 dbSNP
rs750518684 5684 dbSNP
rs1322884455 5695 dbSNP
rs775531250 5697 dbSNP
rs901824078 5711 dbSNP
rs534691371 5723 dbSNP
rs1009586182 5730 dbSNP
rs1230420234 5736 dbSNP
rs1430756203 5736 dbSNP
rs1304675642 5737 dbSNP
rs1020997122 5738 dbSNP
rs996131925 5742 dbSNP
rs1338601646 5749 dbSNP
rs548103317 5753 dbSNP
rs1404674669 5761 dbSNP
rs1159457496 5774 dbSNP
rs1458432598 5780 dbSNP
rs1028985887 5787 dbSNP
rs957400467 5790 dbSNP
rs758458785 5794 dbSNP
rs1158918158 5798 dbSNP
rs1424729505 5803 dbSNP
rs1034255208 5805 dbSNP
rs568283526 5810 dbSNP
rs1367123216 5814 dbSNP
rs989763343 5816 dbSNP
rs1248649790 5822 dbSNP
rs959575669 5823 dbSNP
rs1348892891 5827 dbSNP
rs1260332662 5837 dbSNP
rs1322051251 5847 dbSNP
rs1422361254 5857 dbSNP
rs1301924448 5861 dbSNP
rs762610077 5862 dbSNP
rs183086382 5866 dbSNP
rs747165880 5868 dbSNP
rs1320707218 5877 dbSNP
rs1383405205 5878 dbSNP
rs537117219 5880 dbSNP
rs557112076 5881 dbSNP
rs1382372332 5892 dbSNP
rs1293400381 5894 dbSNP
rs1325619990 5895 dbSNP
rs556884381 5896 dbSNP
rs1370521949 5900 dbSNP
rs977946676 5900 dbSNP
rs972358651 5902 dbSNP
rs1357470045 5904 dbSNP
rs1444500411 5911 dbSNP
rs1391321852 5912 dbSNP
rs143831827 5921 dbSNP
rs1445333181 5933 dbSNP
rs1261329707 5935 dbSNP
rs539583718 5936 dbSNP
rs985259673 5942 dbSNP
rs1293593775 5943 dbSNP
rs1243487159 5950 dbSNP
rs1358731080 5963 dbSNP
rs990475631 5966 dbSNP
rs1203874300 5967 dbSNP
rs148068641 5972 dbSNP
rs553101675 5972 dbSNP
rs1261709259 5977 dbSNP
rs1445615608 5979 dbSNP
rs916194948 5980 dbSNP
rs1041333104 5985 dbSNP
rs930346112 5989 dbSNP
rs1424389295 5992 dbSNP
rs1371767050 5995 dbSNP
rs913141003 6000 dbSNP
rs1474484625 6002 dbSNP
rs781726324 6003 dbSNP
rs756974888 6016 dbSNP
rs1383786333 6018 dbSNP
rs1435186888 6028 dbSNP
rs554945381 6033 dbSNP
rs886724032 6034 dbSNP
rs868820894 6037 dbSNP
rs903889698 6042 dbSNP
rs113579370 6053 dbSNP
rs1055217943 6055 dbSNP
rs1363837803 6059 dbSNP
rs1040559732 6062 dbSNP
rs1336886409 6077 dbSNP
rs1269021337 6078 dbSNP
rs1454942069 6086 dbSNP
rs901928591 6097 dbSNP
rs1280946751 6107 dbSNP
rs996184113 6109 dbSNP
rs1029079739 6116 dbSNP
rs1013766498 6119 dbSNP
rs1384252402 6128 dbSNP
rs1396386050 6130 dbSNP
rs1025591762 6131 dbSNP
rs1470980939 6134 dbSNP
rs1427524854 6144 dbSNP
rs997798299 6147 dbSNP
rs1198912481 6149 dbSNP
rs1480006978 6150 dbSNP
rs1233178683 6151 dbSNP
rs1436068652 6154 dbSNP
rs1453292971 6165 dbSNP
rs893102765 6173 dbSNP
rs1200583617 6178 dbSNP
rs369608267 6179 dbSNP
rs1338391770 6180 dbSNP
rs1380338864 6182 dbSNP
rs572903734 6182 dbSNP
rs1011590229 6185 dbSNP
rs1325006843 6190 dbSNP
rs961587981 6193 dbSNP
rs148131886 6194 dbSNP
rs1351500123 6199 dbSNP
rs1281696338 6203 dbSNP
rs966673226 6206 dbSNP
rs1026598195 6209 dbSNP
rs1335731714 6209 dbSNP
rs1335428542 6223 dbSNP
rs111268666 6228 dbSNP
rs1403953183 6233 dbSNP
rs1034883391 6234 dbSNP
rs575051405 6235 dbSNP
rs753932137 6237 dbSNP
rs1457914527 6243 dbSNP
rs563681377 6244 dbSNP
rs141036331 6245 dbSNP
rs984497469 6246 dbSNP
rs976596972 6247 dbSNP
rs577218230 6251 dbSNP
rs945939394 6253 dbSNP
rs1241640914 6254 dbSNP
rs1461175928 6257 dbSNP
rs1180903356 6270 dbSNP
rs1250869153 6276 dbSNP
rs1420348645 6280 dbSNP
rs1329505686 6283 dbSNP
rs940982474 6284 dbSNP
rs1156233764 6288 dbSNP
rs1043002903 6299 dbSNP
rs1350353924 6301 dbSNP
rs1285337807 6310 dbSNP
rs1040613397 6323 dbSNP
rs925235715 6325 dbSNP
rs1299998300 6326 dbSNP
rs1347224816 6326 dbSNP
rs1470213726 6326 dbSNP
rs531909406 6326 dbSNP
rs1055589522 6327 dbSNP
rs1178541830 6327 dbSNP
rs1406887674 6328 dbSNP
rs1164145071 6329 dbSNP
rs1403597449 6335 dbSNP
rs1447086757 6336 dbSNP
rs1298953509 6337 dbSNP
rs1383295937 6338 dbSNP
rs895217246 6339 dbSNP
rs1375710630 6341 dbSNP
rs1014109897 6377 dbSNP
rs11541076 6378 dbSNP
rs373375003 6379 dbSNP
rs994343492 6380 dbSNP
rs932168501 6383 dbSNP
rs868622816 6393 dbSNP
rs1050911023 6395 dbSNP
rs1018382680 6398 dbSNP
rs1229258525 6406 dbSNP
rs1364121297 6410 dbSNP
rs1205746750 6413 dbSNP
rs1430205066 6414 dbSNP
rs1234967410 6422 dbSNP
rs886448900 6424 dbSNP
rs1162803667 6442 dbSNP
rs1350670999 6442 dbSNP
rs1426278558 6442 dbSNP
rs201562622 6442 dbSNP
rs893249137 6443 dbSNP
rs1184422544 6450 dbSNP
rs748769787 6450 dbSNP
rs1474912537 6452 dbSNP
rs187366448 6452 dbSNP
rs978651781 6452 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HeLa
Disease 11213.0
Location of target site 3'UTR
Tools used in this research TargetScan
Original Description (Extracted from the article) ... "We have shown that miR-155* and miR-155 are differentially regulated by KHSRP and type I IFN. The type I IFN also causes more KHSRP activation by TLR7 through its induction of KHSRP expression ...

- Zhou H; Huang X; Cui H; Luo X; Tang Y; Chen et al., 2010, Blood.

Article - Zhou H; Huang X; Cui H; Luo X; Tang Y; Chen et al.
- Blood, 2010
The recent discovery of microRNAs (miRNAs) has revealed a new layer of gene expression regulation, affecting the immune system. Here, we identify their roles in regulating human plasmacytoid dendritic cell (PDC) activation. miRNA profiling showed the significantly differential expression of 19 miRNAs in PDCs after Toll-like receptor 7 (TLR7) stimulation, among which miR-155* and miR-155 were the most highly induced. Although they were processed from a single precursor and were both induced by TLR7 through the c-Jun N-terminal kinase pathway, miR-155* and miR-155 had opposite effects on the regulation of type I interferon production by PDC. Further study indicated that miR-155* augmented interferon-alpha/beta expression by suppressing IRAKM, whereas miR-155 inhibited their expression by targeting TAB2. Kinetic analysis of miR-155* and miR-155 induction revealed that miR-155* was mainly induced in the early stage of stimulation, and that miR-155 was mainly induced in the later stage, suggesting their cooperative involvement in PDC activation. Finally, we demonstrated that miR-155* and miR-155 were inversely regulated by autocrine/paracrine type I interferon and TLR7-activated KHSRP at the posttranscriptional level, which led to their different dynamic induction by TLR7. Thus, our study identified and validated novel miRNA-protein networks involved in regulating PDC activation.
LinkOut: [PMID: 20852130]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE38226 Liver fibrosis 0.669 4.6e-4 0.603 1.9e-3 21 Click to see details
GSE42095 Differentiated embryonic stem cells 0.527 4.9e-3 0.401 2.9e-2 23 Click to see details
GSE28544 Breast cancer 0.459 1.2e-2 0.523 4.4e-3 24 Click to see details
GSE19783 ER+ ER+ breast cancer 0.368 5.5e-2 0.316 8.7e-2 20 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.307 6.8e-2 0.312 6.4e-2 25 Click to see details
GSE28260 Renal cortex and medulla -0.389 9.4e-2 -0.423 7.5e-2 13 Click to see details
GSE21687 Ependynoma primary tumors -0.13 1.5e-1 -0.138 1.4e-1 64 Click to see details
GSE15076 Monocyte-derived dendritic cells -0.469 1.7e-1 -0.771 3.6e-2 6 Click to see details
GSE26953 Aortic valvular endothelial cells -0.179 2.0e-1 -0.204 1.7e-1 24 Click to see details
GSE19783 ER- ER- breast cancer -0.073 2.6e-1 -0.141 1.1e-1 79 Click to see details
GSE17498 Multiple myeloma 0.086 3.0e-1 0.298 3.1e-2 40 Click to see details
GSE19536 Breast cancer 0.029 3.9e-1 0.006 4.8e-1 100 Click to see details
GSE19350 CNS germ cell tumors -0.023 4.7e-1 0.407 9.5e-2 12 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis -0.014 4.8e-1 -0.564 4.8e-3 20 Click to see details
GSE32688 Pancreatic cancer 0.003 4.9e-1 0.042 4.1e-1 32 Click to see details
GSE32688 Pancreatic cancer 0.003 4.9e-1 0.042 4.1e-1 32 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
KIRP 0.794 0.05 0.900 0.02 5 Click to see details
PRAD -0.739 0.08 -0.600 0.14 5 Click to see details
LUSC 0.227 0.17 0.334 0.08 20 Click to see details
HNSC -0.255 0.17 -0.300 0.13 16 Click to see details
BRCA 0.248 0.19 0.293 0.14 15 Click to see details
PAAD 0.524 0.24 0.400 0.3 4 Click to see details
CHOL -0.526 0.32 -0.500 0.33 3 Click to see details
UCEC -0.241 0.35 0.100 0.44 5 Click to see details
KIRC -0.122 0.37 -0.236 0.26 10 Click to see details
THCA 0.048 0.41 -0.014 0.47 23 Click to see details
ESCA -0.126 0.44 0.400 0.3 4 Click to see details
STAD -0.026 0.47 -0.119 0.36 12 Click to see details
LIHC 0.01 0.49 0.066 0.42 13 Click to see details
LIHC 0.01 0.49 0.066 0.42 13 Click to see details
LIHC 0.01 0.49 0.066 0.42 13 Click to see details
LIHC 0.01 0.49 0.066 0.42 13 Click to see details
73 hsa-miR-155-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT005808 IRAK3 interleukin 1 receptor associated kinase 3 4 1
MIRT082844 ZNF460 zinc finger protein 460 2 4
MIRT256047 UBE2K ubiquitin conjugating enzyme E2 K 2 4
MIRT437787 PTEN phosphatase and tensin homolog 2 1
MIRT456168 ZDHHC6 zinc finger DHHC-type containing 6 2 2
MIRT464916 TXNIP thioredoxin interacting protein 2 4
MIRT475559 HNRNPF heterogeneous nuclear ribonucleoprotein F 2 2
MIRT499608 DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 2 8
MIRT504220 MYO6 myosin VI 2 4
MIRT504256 C1orf147 chromosome 1 open reading frame 147 2 4
MIRT507642 CREBRF CREB3 regulatory factor 2 2
MIRT522858 KIAA1551 KIAA1551 2 2
MIRT527505 MYD88 myeloid differentiation primary response 88 5 2
MIRT530713 ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 2 2
MIRT532851 ZNF699 zinc finger protein 699 2 2
MIRT535952 MIA3 MIA family member 3, ER export factor 2 2
MIRT539041 ATXN1L ataxin 1 like 2 4
MIRT556391 LUC7L LUC7 like 2 2
MIRT558617 CNOT6L CCR4-NOT transcription complex subunit 6 like 2 2
MIRT559869 ATXN3 ataxin 3 2 2
MIRT569208 SHC3 SHC adaptor protein 3 2 2
MIRT573122 C18orf25 chromosome 18 open reading frame 25 2 2
MIRT575076 Ddit4 DNA-damage-inducible transcript 4 2 2
MIRT607597 ABCF3 ATP binding cassette subfamily F member 3 2 6
MIRT609386 PHEX phosphate regulating endopeptidase homolog X-linked 2 2
MIRT610550 MDN1 midasin AAA ATPase 1 2 2
MIRT612390 TCF7L2 transcription factor 7 like 2 2 2
MIRT612910 GTDC1 glycosyltransferase like domain containing 1 2 6
MIRT613314 ARL5C ADP ribosylation factor like GTPase 5C 2 2
MIRT613356 ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 2 4
MIRT613541 CLMP CXADR like membrane protein 2 2
MIRT617029 SYT6 synaptotagmin 6 2 2
MIRT618044 MRVI1 murine retrovirus integration site 1 homolog 2 2
MIRT619307 KIRREL kirre like nephrin family adhesion molecule 1 2 2
MIRT623209 MTFR1L mitochondrial fission regulator 1 like 2 2
MIRT625448 RANGAP1 Ran GTPase activating protein 1 2 2
MIRT634551 MACC1 MACC1, MET transcriptional regulator 2 2
MIRT640740 EPB41 erythrocyte membrane protein band 4.1 2 2
MIRT640906 RAB13 RAB13, member RAS oncogene family 2 2
MIRT644025 ZNF792 zinc finger protein 792 2 2
MIRT651489 WT1 Wilms tumor 1 2 2
MIRT652037 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT669093 CDK6 cyclin dependent kinase 6 2 2
MIRT696720 WNT3 Wnt family member 3 2 2
MIRT698085 TPM1 tropomyosin 1 2 2
MIRT703284 GID4 GID complex subunit 4 homolog 2 2
MIRT707183 ARHGEF33 Rho guanine nucleotide exchange factor 33 2 2
MIRT710362 CREB5 cAMP responsive element binding protein 5 2 2
MIRT713501 DCAF17 DDB1 and CUL4 associated factor 17 2 2
MIRT717153 LRRC3C leucine rich repeat containing 3C 2 2
MIRT719038 ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 2 2
MIRT719489 LSG1 large 60S subunit nuclear export GTPase 1 2 2
MIRT720284 DPYSL3 dihydropyrimidinase like 3 2 2
MIRT732474 NLRP3 NLR family pyrin domain containing 3 2 0
MIRT732620 MS multiple sclerosis 1 0
MIRT732968 TGFBR2 transforming growth factor beta receptor 2 3 0
MIRT733063 AGTR1 angiotensin II receptor type 1 3 0
MIRT733206 ADAM10 ADAM metallopeptidase domain 10 1 0
MIRT733302 CRP C-reactive protein 2 0
MIRT734202 PDCD4 programmed cell death 4 3 0
MIRT734467 SIRT1 sirtuin 1 2 0
MIRT734701 Foxo3 forkhead box O3 1 0
MIRT734889 SP4 Sp4 transcription factor 2 0
MIRT735047 BATF basic leucine zipper ATF-like transcription factor 1 0
MIRT735048 SPI1 Spi-1 proto-oncogene 1 0
MIRT735734 PICALM phosphatidylinositol binding clathrin assembly protein 3 0
MIRT735944 TNF tumor necrosis factor 1 0
MIRT736131 MYLK myosin light chain kinase 2 0
MIRT736780 FOXP3 forkhead box P3 1 0
MIRT736781 CEBPB CCAAT/enhancer binding protein beta 1 0
MIRT736858 WEE1 WEE1 G2 checkpoint kinase 2 0
MIRT736873 TLR3 toll like receptor 3 2 0
MIRT736902 CFH complement factor H 2 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-155 Curcumin NULL 969516 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-155 Cyclophosphamide approved 2907 Quantitative real-time PCR p53+/+ pregnant mice 20170545 2010 down-regulated
miR-155 Estrogen NULL NULL Microarray mouse uterus 20720260 2010 up-regulated
miR-155 Estrogen NULL NULL Quantitative real-time PCR mouse uterus 20720260 2010 up-regulated
miR-155 Camptothecin NULL 24360 Microarray human cancer cells 24252850 2014 down-regulated
miR-155 Cocaine NULL 446220 Quantitative real-time PCR monocyte derived dendritic cells 24391808 2014 down-regulated
miR-155 Glucose NULL 5793 Microarray endothelial cells 24394957 2014 up-regulated
miR-155 Triptolide NULL 107985 Quantitative real-time PCR peripheral blood mononuclear cells (PBMCs) of RA (rheumatoid arthritis) 24909288 2014 down-regulated
miR-155 Medpor NULL NULL Microarray osteoblast-like cells line (MG-63) 18408260 2008 up-regulated
miR-155 Lithium (Li) approved 3028194 Quantitative real-time PCR lymphoblastoid cell lines (LCLs) 19254429 2009 up-regulated
miR-155 Vorinostat (SAHA) approved 5311 Microarray A549 human non-small cell lung cancer cells 19513533 2009 down-regulated
miR-155 Bisphenol A NULL 6623 Microarray immortalized cytotrophoblast cell lines HTR-8 20417706 2010 up-regulated
miR-155 Ginsenoside Rh2 NULL 119307 Microarray human glioma cells U251 21372826 2011 down-regulated
miR-155 Aidi injection NULL NULL Microarray human breast cancer cells 21563499 2011 down-regulated
miR-155 Gemcitabine approved 60750 Quantitative real-time PCR pancreatic cancer 21738581 2011 down-regulated
miR-155 Trichostatin A (TSA) NULL 444732 Microarray apoptosis-resistant breast cancer cells 21971930 2011 up-regulated
miR-155 Arsenic trioxide approved 14888 Quantitative real-time PCR acute promyelocytic leukemia 22072212 2012 up-regulated
miR-155 5-aza-2'-deoxycytidine (5-Aza-CdR) approved 451668 Microarray breast cancer HB2 22076154 2011 down-regulated
miR-155 5-aza-2'-deoxycytidine (5-Aza-CdR) approved 451668 Microarray breast cancer HB2 22076154 2011 up-regulated
miR-155 5-aza-2'-deoxycytidine (5-Aza-CdR) approved 451668 Microarray breast cancer SKBR3 22076154 2011 up-regulated
miR-155 Glucocorticoid NULL NULL Microarray RAW264.7 cells 22326887 2012 down-regulated
miR-155 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miR-155 Temozolomide approved 5394 Quantitative real-time PCR glioblastoma cells. 22722712 2012 up-regulated
miR-155 Glucocorticoid NULL NULL TaqMan low-density array Eosinophilic esophagitis 22815788 2012 up-regulated
miR-155 Adrenaline approved 5816 Quantitative real-time PCR colon cancer HT29 cells 23036199 2012 up-regulated
miR-155 Leptin NULL NULL Quantitative real-time PCR muscles 20800581 2010 down-regulated
miR-155 Morphine approved 5288826 Microarray human monocyte-derived macrophages (h-mdms) infection with HIV-1 20564181 2010 up-regulated
miR-155 Sinomenine NULL 5459308 Quantitative real-time PCR Colitis 24066068 2013 down-regualted
miR-155 Praziquantel approved 4891 Quantitative real-time PCR liver cell lines 25051829 2014 down-regualted
miR-155 Uric acid NULL 1175 Quantitative real-time PCR endothelial cells 23996753 2013 up-regualted
miR-155 Hydroxychloroquine approved 3652 Microarray mesangial cells 24121037 2013 down-regualted
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-155 Tripterygium wilfordii Hook F resistant tissue
hsa-mir-155 Doxorubicin 31703 NSC123127 approved resistant cell line (W1)
hsa-mir-155 Vincristine 5978 approved resistant cell line (W1)
hsa-mir-155 Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)
hsa-miR-155-3p Cisplatin 5460033 NSC119875 approved sensitive High Lung Adenocarcinoma cell line (A549)
hsa-miR-155-3p Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer cell line (HCT-116)
hsa-miR-155-3p Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (H358, H1993)
hsa-miR-155-3p Paclitaxel 36314 NSC125973 approved sensitive Low Breast Cancer cell line (MCF-7, SKBR3, MDA-MB-231)
hsa-miR-155-3p Temozolomide 5394 NSC362856 approved resistant Low Glioblastoma cell line (A172, U87)
hsa-miR-155-3p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-155-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-155-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-155-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-155-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-155-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-155-3p Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-155-3p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide sensitive cell line (Bads-200)

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