miRTarBase - #MIRT006140


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pre-miRNA Information
pre-miRNA hsa-mir-708   
Genomic Coordinates chr11: 79402022 - 79402109
Synonyms MIRN708, hsa-mir-708, MIR708
Description Homo sapiens miR-708 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-708-5p
Sequence 11| AAGGAGCUUACAAUCUAGCUGGG |33
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 2 11 - 79402098 29233923 MiREDiBase
A-to-I 5 11 - 79402095 29233923 MiREDiBase
A-to-I 13 11 - 79402087 29233923 MiREDiBase
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN16303180 8 COSMIC
COSN23012351 21 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1295953344 6 dbSNP
rs1274646751 17 dbSNP
rs775403619 21 dbSNP
rs1454969794 23 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol ZEB2   
Synonyms HSPC082, SIP-1, SIP1, SMADIP1, ZFHX1B
Description zinc finger E-box binding homeobox 2
Transcript NM_001171653   
Other Transcripts NM_014795   
Expression
Putative miRNA Targets on ZEB2
3'UTR of ZEB2
(miRNA target sites are highlighted)		 
>ZEB2|NM_001171653|3'UTR
   1 TAAACTACTGCATTTTAAGCTTCCTATTTTTTTTTCCAGTAGTATTGTTACCTGCTTGAAAACACTGCTGTGTTAAGCTG
  81 TTCATGCACGTGCCTGACGCTTCCAGGAAGCTGTAGAGAGGGACAGAAGGGGCGGTTCAGCCAAGACAGATGTAGACGGA
 161 GTTGGAGCTGGGTATTGTTAAAAACTGCATTATGCAAAAATTTTGTACAGTGTTAAGGCCTAAAAACTGTGTGGTTCAGA
 241 GACTAATTCCTGTGTTTAATAGCATTTATACTTTAAGCACAACTAGAAAATTGTAAGAATTGCACTCTACTTATGTATCA
 321 CTACAAACTTTAAAAAACTATGTCTAATTTATATTAATACATTTTAAAAAGGTGCCCGCACTACCATACATCAGTATTTT
 401 TATTATTATTATTGTTATTCCTTTTTAATTTAATGTGCTCGCACTACAATGCATCAGTATTATGATTCCTCTGTACTTTC
 481 CTTTCGCTATTCATCAATTTCCCATTTTTTTTTTCAGCTTAAGTAACCACACAATTTTAGGCCTCAATTTTTTTTTTTTT
 561 CTGTGAAGGAACTTGAAGTGATGCATGTGTGAATTTAAGATACCGAAGTCTTAAAGTGACCTGGACGTGAAGGAAAAAGT
 641 AAGATGAGAAATAAAGAAAGCCTTTGTAAGGTGGTTTTAAAAGCCTTATATGCAAACCTTTTAATCTGTGTTTCTGCAAG
 721 TGCCATCCTTGTACAGTGTTAAGAGGGTAACATGGGTTACCTTTGCACCAGCTTCAGTGTTAAGCTCACCCTGTTCTTTG
 801 AAGCACCCATGTCAGTATTAGAAGAATAGGCAGCAGTTCCTTAGTTTACATATGTTTGTGCAATTATTTTCTGTACTTTT
 881 TTGTTCATTAATTTTGTCAGTATTACACCAAACTGTTTTTGCAACAAAAAAATTTTTTTTGCATTCATTTAATTTTAGGT
 961 CAAATAACATTTTATTTATGTGGCTCATTTTATATTTCCTAATTTTATTTATTTCATACTGTAGTGTACAGTATTATAGT
1041 TCTTCAATATATAGATATATTTTAGTAAAAAAGGAACATGACGTTGATCATTTGGGCAAATTTTACGTAAAGAGAAGAGC
1121 ATTTATTGTGTTTTGGAACATTAATTGTGAGATGGGATTTTTCAATTTTATTATTTTATTTTTGTTTTTTTCCAATTACT
1201 GGAAATTCCAAATTTGGGAACTTTTGATACGATCTTGTGAAAACACTGTATTTTCGACTGAAAATTCCACTTTCTTCATC
1281 TTGTTTTTTAGCTAAAAAGAGGGACTGTTAAATACAATGTATGATACCATGACAAAAATCTTTCCTGAATTGTCTTTGTA
1361 AAAGTATTATTGAATTTTCAATTTGTAATTTCTTTTGAAAATGACCATGCTCGAATAAAAATGTAGCCAAACTAAGAATG
1441 TAGTTAATGAGTTCTGTACTTTTAGAGAGTTTTCCTTCAATGACCATTAACATGTAACATGCTTTATGCTTATAATAATG
1521 CTAATTATGTTTTTTTCATATAATTTTAGTTTAGCAATAATTTTGACTGGTACCAATAACTGTTTTTTAAAATTCCATAC
1601 CTATGTACAGCAATTTTACAGCTTTTCTCAACTGATCCTGATTCCAGATTGTGTATTTTTATGTGAGGTTATATTATTCA
1681 AATTTAGTCTATTTACTTTACAGACATTTCTACTTTTGCATTACGAGTATTTAGAGATTATGTGTTAAAAATTCACTTCT
1761 CTGTCCAAGGGGTCTTTGTGATTTATTCAAAAAAAAGTCTAATTTCAAAAAGACAGCTATTATTCAGTGTTATTTATAAT
1841 ATGTAACCTTTTTTAAAGGATTGGGATAGTTTATCTCACTTTTTGAAATGCAGACAGTAGTTTACCGTTTATCTGAAACT
1921 AGAAGGCGTGGGTGGGAGAGGAAAAGCTAAAAGCAAATGCTAACAAAAATAACCGTGATTTTCTAAGACAGTTTTTCAGT
2001 TTTTACAAGATGACCCTAATATTCAGAATATGAATGTATTCGTAGGTTTTACATAATGACTTTTATCAAGAAACTAGATT
2081 CTGCTTCTTAAATCTAATTGCCAAGTGAAGAATAACAGAAAAAACAGATTACCTTATCAAATTTACAGCTCTTGAATATA
2161 CAGAACTATAATATAGTAGCTGTCCATGTATTTTTTCTACTTTAGAATCAAAGAAGAAAAGCATCATTTTGCTATTAAAT
2241 TTGCTAAAATTTTGAGTATGATATTTCCAGTTGGCAAGAACAACATATTTATATTTATTCCTTAGCCATAATACCACTTT
2321 CCTAAATTTCACAAAAGTCATTCTTTGCAACTTGAAACTCAATAGAAAGTGTGTATGTGTGTGTGTGTATATATATATAT
2401 ATATACACACACACACATACACAGAAAGGATGTAATGAAGATACAGTAATAGTTGAGCAGACCTTTTTAGAAAAACATGT
2481 TTTTAGCTCTATCTTCAAACTTTCTGGCAGAGGGGGTGGGGGGGGCAGGGGGAGGAGTGGCATCAAAATGCTATGCCTCC
2561 TGTTATCCACAGCCTAGAGTTTTTATATTTGGAAAGTTTAGAAAATTCTATCCTCGTTTCTCCTTCTTTGAATGGCACAA
2641 ATAAATACACTACATAAATTTTTCTGGTTTGAAAGGCTCTAGGCGATAACTTTATTAATTCAACCTGAAAATATCAAGCC
2721 ATTAAATTTTGTCCGGGTAGAATAAATCCCTGTGGCCTCTTTTAAAGCAATGTAGGTCTCTGTTGCCCATGGGGCATATC
2801 TGTGTCCCAATCCACAAGAGATAGGACCAACAAACAATGAATGTGCAACCTAACTCTTTCTCCTTGGAAAGAAGAAAGTG
2881 TGCACGAAGTAGAGGAGGGTGGGCAGACCCTGCCTTGCCCCTCCTGTTACCCCCTTCTCTGTCATTTGTTCCTAACTCCA
2961 TTTCATAGGCAGGCTCAGAATACCTGAGTCTGAAAATATCAGGATAACACTTGTGAATTGTGACAATCACTACAATGTCC
3041 CATATCTGAGGAGTTTTTTTTAATGCTATTTATCCGCTGGACACGATTGCACATTAGGGCTGCATAATCCTCTAACTCTA
3121 GGGAAAAATAAAAACTTTTGATTTGTCTTAAGATTCTTCTCCAAGGTCGCAAACAAGAAATTCCCCTCCACAACCAAGAG
3201 ATGTGCATTTTAGTAACATCAGATGTGTTCTTCTGTTTTATCAACTACTTACTCTTCCCACACGCTTAGTTCTAAATCTA
3281 ACCTTTCCCCCCTCGAATAGGGGGCAGGGGAGGATGAGGAAACACTGGAACAACTGAACACCCCTGCCCATTTTCTCCAA
3361 GAGCCTTTTGTATTCTAGCATATCTGTGCAATCTTTTCTTTTTTCTTCACATGACACTGTAAGCTTAGGCCTGAAATAAC
3441 TGGGAAGAGAGATGCGTATCAGAATTTCTCCGCAAGAGCTAAACAAAACATACATCTTCCTTAGCATGAATTGGACTGGG
3521 GGCGGAGTGGGAGGGCTTGGAGGAAAGGGGAAAGAAGGGACTATATTTGAATAAATATGAATAAATGTATTAGATACTTT
3601 TCACAATCAGATAACTTTTAAAAAGGTCATTTTTTATCTTTCTAATAATGTAAGCCTTAATAAAAGCAAATCTTAGTCAC
3681 AAATTTGAGGAGACTGCCCAATAATAAGTTTACATGTATTTGAACTGAAAAATTGTTAACCATGCTTTTGCTCCAAGATG
3761 TGTGAGGCCATTCAGGGGCTGTAGGGCCCTGGATATACACACAAACAAGTGTGTGTATATCTGGAGCCCCACACATTGTA
3841 ATAAACACAGCTGCATTTATTTGACTATGTGATCCCATGTACATGTAAAAACATTCAAACAAACACACTCAGCGGATTTA
3921 TTTATTGTGCAATGGGGCAATTATTCAAATAAACATGCTCAATGCAATTATTTGAATCTCACATTGCATGTTCATCAATC
4001 ATAGCACTAAAAAAAGAGGGGGAAAAAACACCAAAGAATTCACATGGGGAAAAAATATATATATGAAAACCACCTTATTA
4081 TAGATTTTATAGGGCAGCTGAGGTTATGGCTCCCTTCTTAACTGTAACTCAACTATTCTGTATTCAATGACATTTGTTTC
4161 TAATGATTAATTGGTTCACTCACTTGATCATATAATAGCAAACTTTATAAACCTGTATTGTGTAGAGATGTGAAATCTCT
4241 ATATTTCAAGAGCAGAAGAGTTCTTTCTAGACACCTTACATCAAGGGACACTGGTCCAATTATTATCGCTTATATAAGCA
4321 CTCCTATAAATTCTGAAAAATTTTATACATGCAACAAAACATTCCTACATTTGAAGACATTAAGAAAAATCACAGGTGAC
4401 TCATCTGATCATTCTATATATTAATAAATATTATGACATATATGTGAACACATCACAAATCATATTGGTGTACCAAGAGG
4481 CAATTTATGCCTCTCTTAAGTATGTACTGACATAACCTAATATACTAAAATGGGAAGGGGCTTTTAGTCACTGAAATATG
4561 CATCGTGTAACAAAGATGAAGAAAATACATGGCTTGTGCCCATCATAAAAAAAGATTCAGACTGAAGGCTTAGCTTTGGT
4641 TTTTTCAATTAAATTGTTAAACTGTGCACAGTGATTTTTTTTTAGAACTTGAGACATTTGTGATGTTGGCTGTTTAAATC
4721 TTTGTTACCTTCGCTGTGAATTGAAATTGTACATATTTAGTAAATCATGCAGACAAAACAAACTTTTTAGACAATATTTT
4801 TATTGGAGAGTTTTCTTTTCCTGTATCCATGTTAAAAAAAAAAAAGACCTCCTTTCCCAAAATAAAAATGTCAATACTAA
4881 ATTTAAAGAAGTATAAAGGAATGATTGCTTCCTTTAGAGCAAAATATTTAAATAAACATGGAGATAATTGGCAACATGTT
4961 CTTTTTGGGCTAGTAGGCTGTGTCCAATTTTTTGGGTCTGATGTTTCAGAGGGCCTCTGTTTCAGGGTTGAAGATGATAT
5041 ATTAATCTCGGAATTAAACAAATGCTATTAAATAAC
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gggucGAUCUAACAUUCG-AGGAa 5'
               ||: ||| ||||| |||| 
Target 5' aactaCTGCATTTTAAGCTTCCTa 3'
 3 - 26 138.00 -12.60
2 
miRNA  3' ggGUCGA-UCUAACAUUCGAGGaa 5'
            ||||| ||:|| | :|||||  
Target 5' ggCAGCTGAGGTTAT-GGCTCCct 3'
 4093 - 4115 136.00 -18.40
3 
miRNA  3' gggucgaUCUAACAU-UCGAGGAa 5'
                 | ||| || |||||:| 
Target 5' ccttatcAAATT-TACAGCTCTTg 3'
 2132 - 2154 135.00 -6.65
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
387314 6 ClinVar
331297 36 ClinVar
331291 515 ClinVar
331292 515 ClinVar
331289 561 ClinVar
331290 561 ClinVar
331286 1120 ClinVar
331278 1797 ClinVar
331274 1946 ClinVar
331271 1985 ClinVar
331265 2389 ClinVar
331263 2397 ClinVar
331259 2406 ClinVar
331260 2406 ClinVar
331261 2406 ClinVar
331262 2406 ClinVar
331258 2517 ClinVar
331256 2526 ClinVar
331228 4846 ClinVar
331229 4846 ClinVar
331230 4846 ClinVar
COSN21017571 16 COSMIC
COSN27005638 44 COSMIC
COSN30447075 52 COSMIC
COSN30118719 64 COSMIC
COSN30114347 68 COSMIC
COSN31483775 82 COSMIC
COSN31514589 105 COSMIC
COSN30512904 120 COSMIC
COSN31612512 133 COSMIC
COSN15951507 165 COSMIC
COSN31524630 245 COSMIC
COSN31961723 319 COSMIC
COSN26643355 356 COSMIC
COSN21784498 378 COSMIC
COSN31583081 400 COSMIC
COSN19593039 425 COSMIC
COSN30137170 427 COSMIC
COSN8759968 468 COSMIC
COSN9861837 480 COSMIC
COSN31553248 487 COSMIC
COSN1225773 504 COSMIC
COSN31542597 506 COSMIC
COSN31517250 511 COSMIC
COSN30175151 524 COSMIC
COSN30117980 540 COSMIC
COSN30143797 543 COSMIC
COSN30142652 551 COSMIC
COSN30120034 568 COSMIC
COSN20050777 580 COSMIC
COSN31516677 605 COSMIC
COSN31520343 605 COSMIC
COSN31520353 610 COSMIC
COSN13939537 626 COSMIC
COSN30118880 630 COSMIC
COSN30529387 640 COSMIC
COSN20056027 654 COSMIC
COSN24299239 663 COSMIC
COSN19371280 687 COSMIC
COSN9066030 702 COSMIC
COSN30533099 723 COSMIC
COSN31597438 734 COSMIC
COSN31543270 765 COSMIC
COSN31595458 791 COSMIC
COSN8759967 827 COSMIC
COSN19005564 875 COSMIC
COSN31523405 907 COSMIC
COSN22654394 932 COSMIC
COSN31483212 1054 COSMIC
COSN9066029 1077 COSMIC
COSN17759038 1082 COSMIC
COSN31608215 1213 COSMIC
COSN31565239 1231 COSMIC
COSN31520336 1287 COSMIC
COSN21724596 1413 COSMIC
COSN20629085 1487 COSMIC
COSN29414834 1509 COSMIC
COSN1794856 1519 COSMIC
COSN15991197 1673 COSMIC
COSN21451011 1806 COSMIC
COSN9066028 1975 COSMIC
COSN15212893 2254 COSMIC
COSN6677808 2387 COSMIC
COSN18927195 2388 COSMIC
COSN20195821 2404 COSMIC
COSN21483769 2514 COSMIC
COSN7345013 2555 COSMIC
COSN22868459 3054 COSMIC
COSN29393402 3564 COSMIC
COSN6194665 3898 COSMIC
COSN9066027 4216 COSMIC
COSN24436869 4307 COSMIC
COSN24037957 4335 COSMIC
COSN7345012 4347 COSMIC
COSN5782697 4415 COSMIC
COSN15836051 4450 COSMIC
COSN14823780 4456 COSMIC
COSN9228312 4619 COSMIC
COSN1794854 4630 COSMIC
COSN1794853 4648 COSMIC
COSN29593645 4675 COSMIC
COSN27339723 4834 COSMIC
COSN29422042 4834 COSMIC
COSN21624460 5223 COSMIC
COSN8270336 5295 COSMIC
rs79710863 1965 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1057522759 6 dbSNP
rs1300620293 7 dbSNP
rs1423228755 20 dbSNP
rs1365495240 26 dbSNP
rs1301719814 27 dbSNP
rs760638171 30 dbSNP
rs956837501 35 dbSNP
rs567229506 36 dbSNP
rs767414356 36 dbSNP
rs775544700 38 dbSNP
rs772085577 39 dbSNP
rs1327738532 43 dbSNP
rs759246452 44 dbSNP
rs774259900 45 dbSNP
rs1024046441 63 dbSNP
rs1360111638 66 dbSNP
rs1012279489 67 dbSNP
rs1263469141 69 dbSNP
rs1407695241 83 dbSNP
rs896568335 85 dbSNP
rs1264109676 98 dbSNP
rs1445401073 106 dbSNP
rs1187970003 107 dbSNP
rs886054896 116 dbSNP
rs940761801 122 dbSNP
rs1162164017 123 dbSNP
rs1470574152 124 dbSNP
rs1454616056 125 dbSNP
rs1289135454 134 dbSNP
rs1386638176 153 dbSNP
rs774457208 157 dbSNP
rs771297035 159 dbSNP
rs531395694 172 dbSNP
rs1382811131 178 dbSNP
rs1171174781 193 dbSNP
rs1454515760 202 dbSNP
rs1310481647 234 dbSNP
rs1048904059 248 dbSNP
rs1239477709 252 dbSNP
rs1262759157 273 dbSNP
rs1327386805 277 dbSNP
rs1208295194 290 dbSNP
rs1373796308 293 dbSNP
rs930525890 309 dbSNP
rs1180680334 312 dbSNP
rs1462659834 312 dbSNP
rs1192788923 340 dbSNP
rs1420090917 344 dbSNP
rs1463561513 346 dbSNP
rs1245021031 358 dbSNP
rs921900462 360 dbSNP
rs1455327093 375 dbSNP
rs974360520 377 dbSNP
rs1406257062 379 dbSNP
rs944410468 381 dbSNP
rs1460811873 388 dbSNP
rs1276487172 390 dbSNP
rs190200609 392 dbSNP
rs1391857705 399 dbSNP
rs760953941 411 dbSNP
rs955835380 412 dbSNP
rs1263988709 414 dbSNP
rs1339834644 414 dbSNP
rs551537387 421 dbSNP
rs1208066000 429 dbSNP
rs1255446297 431 dbSNP
rs979655517 432 dbSNP
rs1179402504 435 dbSNP
rs150808707 440 dbSNP
rs1384600680 441 dbSNP
rs1023927713 449 dbSNP
rs1429527818 453 dbSNP
rs376158913 459 dbSNP
rs141707372 467 dbSNP
rs1012243678 479 dbSNP
rs896452444 480 dbSNP
rs1462447922 481 dbSNP
rs34428991 482 dbSNP
rs1299752205 483 dbSNP
rs1035019255 486 dbSNP
rs1408965885 489 dbSNP
rs886054895 496 dbSNP
rs1347651535 500 dbSNP
rs1004946924 502 dbSNP
rs1332777008 504 dbSNP
rs1308081896 514 dbSNP
rs558553086 515 dbSNP
rs886054894 515 dbSNP
rs1195768464 525 dbSNP
rs1489855101 534 dbSNP
rs1268086198 539 dbSNP
rs1222997488 543 dbSNP
rs1323261451 545 dbSNP
rs1271174979 546 dbSNP
rs1214161411 547 dbSNP
rs1340156886 548 dbSNP
rs930516484 554 dbSNP
rs55711724 557 dbSNP
rs1189045027 561 dbSNP
rs533637050 561 dbSNP
rs765427791 561 dbSNP
rs776839248 561 dbSNP
rs769004459 562 dbSNP
rs1310789481 563 dbSNP
rs1345481078 564 dbSNP
rs1444006140 565 dbSNP
rs1304258784 566 dbSNP
rs1439083509 568 dbSNP
rs769850418 570 dbSNP
rs1388208559 577 dbSNP
rs900410529 578 dbSNP
rs1326454609 582 dbSNP
rs1408954846 584 dbSNP
rs1423876410 600 dbSNP
rs748374819 601 dbSNP
rs567717982 602 dbSNP
rs911535836 604 dbSNP
rs1199999297 610 dbSNP
rs1489358765 618 dbSNP
rs1230896704 620 dbSNP
rs1216382125 623 dbSNP
rs1438134130 626 dbSNP
rs146793389 632 dbSNP
rs1342115986 645 dbSNP
rs1247290739 646 dbSNP
rs1294423252 648 dbSNP
rs1450167887 653 dbSNP
rs988451889 656 dbSNP
rs1485929808 661 dbSNP
rs869206626 661 dbSNP
rs925752534 674 dbSNP
rs980008683 680 dbSNP
rs968277146 690 dbSNP
rs916755135 693 dbSNP
rs1415777386 712 dbSNP
rs1271991744 741 dbSNP
rs1202849486 743 dbSNP
rs1345980224 743 dbSNP
rs991030187 745 dbSNP
rs1318648222 753 dbSNP
rs1364476652 754 dbSNP
rs1361137570 770 dbSNP
rs867687507 789 dbSNP
rs1453993447 794 dbSNP
rs1315331554 795 dbSNP
rs1403619787 810 dbSNP
rs1285339890 827 dbSNP
rs1317162205 831 dbSNP
rs1210140137 833 dbSNP
rs756632437 834 dbSNP
rs1244519667 837 dbSNP
rs1245668522 852 dbSNP
rs960964115 853 dbSNP
rs62169203 858 dbSNP
rs1034989604 860 dbSNP
rs1376382997 871 dbSNP
rs1282893252 877 dbSNP
rs1471711439 879 dbSNP
rs1181100622 881 dbSNP
rs1408382126 900 dbSNP
rs1459037478 906 dbSNP
rs1157135014 915 dbSNP
rs1388089700 916 dbSNP
rs1470339236 921 dbSNP
rs1336777640 927 dbSNP
rs541011980 932 dbSNP
rs1447876613 933 dbSNP
rs529571252 933 dbSNP
rs1352640645 941 dbSNP
rs1027777794 942 dbSNP
rs780717462 944 dbSNP
rs562043405 955 dbSNP
rs995339152 959 dbSNP
rs1203715377 966 dbSNP
rs1280079081 970 dbSNP
rs1440653273 971 dbSNP
rs1307805410 997 dbSNP
rs900295151 1016 dbSNP
rs1411486489 1028 dbSNP
rs1428283277 1029 dbSNP
rs1367619827 1044 dbSNP
rs754471199 1050 dbSNP
rs544037596 1055 dbSNP
rs1164453180 1074 dbSNP
rs1428276017 1077 dbSNP
rs1400081004 1082 dbSNP
rs1008741216 1083 dbSNP
rs1330136326 1087 dbSNP
rs890402517 1088 dbSNP
rs1372852840 1092 dbSNP
rs1408363199 1096 dbSNP
rs1404795206 1099 dbSNP
rs1411741214 1106 dbSNP
rs751200033 1107 dbSNP
rs1179071535 1112 dbSNP
rs1342180250 1113 dbSNP
rs1199871047 1117 dbSNP
rs1052703427 1119 dbSNP
rs534438826 1120 dbSNP
rs925688118 1124 dbSNP
rs1250732817 1132 dbSNP
rs576521612 1150 dbSNP
rs1490577800 1185 dbSNP
rs1201185884 1192 dbSNP
rs1376058527 1194 dbSNP
rs1042775988 1209 dbSNP
rs1179679807 1213 dbSNP
rs1169047701 1221 dbSNP
rs570280023 1230 dbSNP
rs550711574 1231 dbSNP
rs56015719 1237 dbSNP
rs916724243 1246 dbSNP
rs990997836 1255 dbSNP
rs765985290 1256 dbSNP
rs545544880 1276 dbSNP
rs1285713287 1283 dbSNP
rs983855107 1287 dbSNP
rs1298297152 1290 dbSNP
rs1344272590 1292 dbSNP
rs1226003636 1316 dbSNP
rs1223920159 1318 dbSNP
rs1374671090 1326 dbSNP
rs1356778443 1327 dbSNP
rs869146174 1333 dbSNP
rs1211914772 1339 dbSNP
rs62169202 1370 dbSNP
rs1451148014 1380 dbSNP
rs886054893 1405 dbSNP
rs1028072325 1412 dbSNP
rs1408312978 1413 dbSNP
rs761449636 1454 dbSNP
rs1168433684 1456 dbSNP
rs910719372 1466 dbSNP
rs745421150 1470 dbSNP
rs1303932090 1474 dbSNP
rs1435995901 1493 dbSNP
rs180857599 1499 dbSNP
rs967763276 1510 dbSNP
rs1385841911 1518 dbSNP
rs1320651315 1519 dbSNP
rs1366652577 1522 dbSNP
rs1021991513 1526 dbSNP
rs1432889380 1529 dbSNP
rs1296762317 1537 dbSNP
rs987787711 1540 dbSNP
rs1008710167 1541 dbSNP
rs535437890 1549 dbSNP
rs1156897284 1550 dbSNP
rs1355940503 1551 dbSNP
rs890372851 1566 dbSNP
rs956845111 1574 dbSNP
rs1269308802 1589 dbSNP
rs878997586 1591 dbSNP
rs999184812 1599 dbSNP
rs537106016 1602 dbSNP
rs1043132571 1611 dbSNP
rs1425971943 1613 dbSNP
rs1185911608 1614 dbSNP
rs1368212075 1622 dbSNP
rs1457096413 1632 dbSNP
rs948468404 1633 dbSNP
rs1487298232 1636 dbSNP
rs886054892 1637 dbSNP
rs1243544813 1639 dbSNP
rs915691461 1644 dbSNP
rs1379837514 1646 dbSNP
rs1055279522 1654 dbSNP
rs1034978994 1661 dbSNP
rs574826307 1665 dbSNP
rs371597487 1670 dbSNP
rs1310317743 1681 dbSNP
rs556143599 1691 dbSNP
rs1315817386 1692 dbSNP
rs756337689 1692 dbSNP
rs761671531 1704 dbSNP
rs1184863113 1714 dbSNP
rs1023411835 1724 dbSNP
rs1326338995 1725 dbSNP
rs1012967328 1731 dbSNP
rs1208159551 1734 dbSNP
rs1284289376 1739 dbSNP
rs920579229 1751 dbSNP
rs1219071782 1752 dbSNP
rs1199191784 1754 dbSNP
rs887839277 1761 dbSNP
rs1049052683 1765 dbSNP
rs1182503947 1766 dbSNP
rs192270522 1769 dbSNP
rs886054891 1770 dbSNP
rs929287417 1774 dbSNP
rs1157812791 1777 dbSNP
rs753802772 1788 dbSNP
rs1040666861 1792 dbSNP
rs1300996315 1794 dbSNP
rs886054890 1797 dbSNP
rs964749903 1797 dbSNP
rs1290494714 1799 dbSNP
rs987261219 1803 dbSNP
rs74583908 1817 dbSNP
rs1302072133 1820 dbSNP
rs1314014596 1823 dbSNP
rs1231796920 1825 dbSNP
rs1255894365 1826 dbSNP
rs1470899272 1831 dbSNP
rs886054889 1839 dbSNP
rs1250017841 1846 dbSNP
rs1481872034 1847 dbSNP
rs1176210337 1853 dbSNP
rs370864625 1861 dbSNP
rs1431240473 1866 dbSNP
rs1021277438 1873 dbSNP
rs946453175 1880 dbSNP
rs539580957 1887 dbSNP
rs1368395110 1895 dbSNP
rs1012611270 1902 dbSNP
rs1409511085 1906 dbSNP
rs796295921 1907 dbSNP
rs1186771177 1908 dbSNP
rs768430700 1918 dbSNP
rs1035080775 1919 dbSNP
rs982080371 1926 dbSNP
rs187376396 1927 dbSNP
rs1231172614 1928 dbSNP
rs1023442876 1930 dbSNP
rs1005302630 1931 dbSNP
rs1272950457 1939 dbSNP
rs547434217 1943 dbSNP
rs886054888 1946 dbSNP
rs1341879991 1959 dbSNP
rs1245640194 1962 dbSNP
rs79710863 1965 dbSNP
rs141141594 1974 dbSNP
rs897847759 1975 dbSNP
rs547033833 1982 dbSNP
rs1450006407 1983 dbSNP
rs10179925 1984 dbSNP
rs771457697 1985 dbSNP
rs886054887 1985 dbSNP
rs889334336 1988 dbSNP
rs558354594 1992 dbSNP
rs946903717 1997 dbSNP
rs1456548960 1998 dbSNP
rs1293023083 2005 dbSNP
rs1365949612 2024 dbSNP
rs1364786715 2026 dbSNP
rs1295492951 2037 dbSNP
rs531956200 2041 dbSNP
rs1052216211 2042 dbSNP
rs935062147 2052 dbSNP
rs112075123 2055 dbSNP
rs886054886 2060 dbSNP
rs745578574 2065 dbSNP
rs1356081092 2073 dbSNP
rs1190482564 2082 dbSNP
rs954809289 2083 dbSNP
rs1031473446 2086 dbSNP
rs1170940409 2093 dbSNP
rs1415611366 2100 dbSNP
rs1448467887 2110 dbSNP
rs1388006875 2113 dbSNP
rs1164462217 2115 dbSNP
rs767629274 2116 dbSNP
rs1444723840 2118 dbSNP
rs1257436537 2133 dbSNP
rs1200412677 2142 dbSNP
rs1482591336 2150 dbSNP
rs977685244 2166 dbSNP
rs982161132 2168 dbSNP
rs780639220 2173 dbSNP
rs969279963 2177 dbSNP
rs1021999455 2180 dbSNP
rs886054885 2181 dbSNP
rs559933124 2182 dbSNP
rs546354893 2184 dbSNP
rs983994066 2186 dbSNP
rs1226310058 2197 dbSNP
rs1377351172 2197 dbSNP
rs375576732 2203 dbSNP
rs1292265232 2213 dbSNP
rs1329306902 2219 dbSNP
rs1012580156 2220 dbSNP
rs1265654124 2231 dbSNP
rs894112213 2246 dbSNP
rs1210660647 2248 dbSNP
rs952584966 2249 dbSNP
rs1471685969 2256 dbSNP
rs1025878143 2262 dbSNP
rs1187549991 2264 dbSNP
rs1412944779 2269 dbSNP
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rs572214712 2274 dbSNP
rs1035374459 2278 dbSNP
rs1336699854 2281 dbSNP
rs962417041 2281 dbSNP
rs866753388 2283 dbSNP
rs1272767800 2284 dbSNP
rs1308967544 2287 dbSNP
rs1350764179 2291 dbSNP
rs1229781499 2294 dbSNP
rs189175137 2300 dbSNP
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rs1219810402 2315 dbSNP
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rs779311047 2843 dbSNP
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rs1344071991 2900 dbSNP
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rs1016371292 2931 dbSNP
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rs912379812 2956 dbSNP
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rs953413895 2990 dbSNP
rs181137747 2998 dbSNP
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rs1391082156 3000 dbSNP
rs1157389006 3002 dbSNP
rs903143214 3002 dbSNP
rs989441097 3004 dbSNP
rs886054879 3010 dbSNP
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rs958322556 3018 dbSNP
rs1412617766 3024 dbSNP
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rs568496975 3262 dbSNP
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rs556327734 3264 dbSNP
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rs1451485131 3282 dbSNP
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rs1356193268 3310 dbSNP
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rs1001561801 4023 dbSNP
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rs940242232 4312 dbSNP
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rs1382426213 5000 dbSNP
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rs965319710 5334 dbSNP
rs1437523191 5342 dbSNP
rs573540313 5345 dbSNP
rs1276856701 5350 dbSNP
rs1343081182 5360 dbSNP
rs1218721664 5362 dbSNP
rs992703837 5365 dbSNP
rs1273727715 5368 dbSNP
rs566205203 5369 dbSNP
rs1197297115 5371 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HK2 , A-498 , Caki-2
Disease Renal cell carcinoma
Location of target site 3'UTR
Tools used in this research miRanda
Original Description (Extracted from the article) ... 3'UTR of ZEB2 and BMI1 are functional targets of miR-708 in renal cancer ...

- Saini S; Yamamura S; Majid S; Shahryari V; et al., 2011, Cancer research.

Article - Saini S; Yamamura S; Majid S; Shahryari V; et al.
- Cancer research, 2011
Cancer pathogenesis is restricted by stresses that compromise cell division and survival. In this study, we identify miR-708, a little studied member of a set of microRNAs that have been implicated in stress control, as an important tumor suppressor in renal cell carcinoma (RCC). miR-708 expression was attenuated widely in human RCC specimens. Restoration of miR-708 expression in RCC cell lines decreased cell growth, clonability, invasion, and migration and elicited a dramatic increase in apoptosis. Moreover, intratumoral delivery of miR-708 was sufficient to trigger in vivo regression of established tumors in murine xenograft models of human RCC. Investigation of the targets of miR-708 identified the inhibitor of apoptosis protein survivin as important. siRNA-mediated knockdown of survivin partially phenocopied miR-708 overexpression suggesting that the proapoptotic role of miR-708 may be mediated primarily through survivin regulation. Additionally, we identified the E-cadherin regulators ZEB2 and BMI1 as likely miR-708 targets. Taken together, our findings define a major tumor suppressive role for miR-708, which may offer an attractive new target for prognostic and therapeutic intervention in RCC.
LinkOut: [PMID: 21852381]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE38226 Liver fibrosis 0.654 6.5e-4 0.710 1.6e-4 21 Click to see details
GSE21687 Ependynoma primary tumors 0.295 9.0e-3 0.230 3.4e-2 64 Click to see details
GSE28544 Breast cancer -0.477 9.2e-3 -0.462 1.2e-2 24 Click to see details
GSE35602 Colorectal cancer stromal tissue -0.453 1.1e-2 0.196 1.7e-1 25 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.432 1.6e-2 -0.193 1.8e-1 25 Click to see details
GSE19350 CNS germ cell tumors 0.482 5.6e-2 0.497 5.0e-2 12 Click to see details
GSE32688 Pancreatic cancer 0.2 1.4e-1 0.071 3.5e-1 32 Click to see details
GSE19536 Breast cancer 0.099 1.6e-1 0.094 1.8e-1 100 Click to see details
GSE19783 ER+ ER+ breast cancer 0.199 2.0e-1 0.143 2.7e-1 20 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.698 2.5e-1 0.500 3.3e-1 3 Click to see details
GSE28260 Renal cortex and medulla 0.128 3.4e-1 -0.016 4.8e-1 13 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.097 3.4e-1 -0.376 5.1e-2 20 Click to see details
GSE19783 ER- ER- breast cancer -0.025 4.1e-1 -0.001 5.0e-1 79 Click to see details
GSE26953 Aortic valvular endothelial cells -0.044 4.2e-1 -0.214 1.6e-1 24 Click to see details
GSE17498 Multiple myeloma -0.03 4.3e-1 0.005 4.9e-1 40 Click to see details
GSE42095 Differentiated embryonic stem cells 0.017 4.7e-1 -0.088 3.4e-1 23 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
LIHC 0.531 0 0.537 0 41 Click to see details
CHOL 0.75 0.02 0.881 0 8 Click to see details
HNSC -0.323 0.02 -0.328 0.02 42 Click to see details
PRAD -0.248 0.04 -0.206 0.08 50 Click to see details
BLCA -0.401 0.05 -0.375 0.06 18 Click to see details
BRCA 0.17 0.06 0.211 0.03 84 Click to see details
THCA 0.181 0.09 0.058 0.33 59 Click to see details
LUSC -0.217 0.1 -0.180 0.14 38 Click to see details
KIRP 0.218 0.12 0.190 0.15 32 Click to see details
LUAD 0.288 0.18 0.336 0.14 12 Click to see details
PAAD -0.583 0.21 -0.600 0.2 4 Click to see details
ESCA -0.272 0.21 -0.327 0.16 11 Click to see details
UCEC 0.194 0.21 0.195 0.21 19 Click to see details
KIRC 0.096 0.22 0.057 0.32 68 Click to see details
PCPG -0.765 0.22 -0.500 0.33 3 Click to see details
KICH -0.155 0.23 -0.217 0.15 24 Click to see details
CESC -0.482 0.34 -0.500 0.33 3 Click to see details
STAD -0.011 0.48 -0.095 0.3 32 Click to see details
STAD -0.011 0.48 -0.095 0.3 32 Click to see details
STAD -0.011 0.48 -0.095 0.3 32 Click to see details
STAD -0.011 0.48 -0.095 0.3 32 Click to see details
82 hsa-miR-708-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT006139 BMI1 BMI1 proto-oncogene, polycomb ring finger 4 1
MIRT006140 ZEB2 zinc finger E-box binding homeobox 2 4 1
MIRT006141 BIRC5 baculoviral IAP repeat containing 5 4 1
MIRT006473 AKT2 AKT serine/threonine kinase 2 2 1
MIRT006474 CD44 CD44 molecule (Indian blood group) 2 1
MIRT006941 TMEM88 transmembrane protein 88 2 1
MIRT037743 RANBP2 RAN binding protein 2 1 1
MIRT037744 RNF41 ring finger protein 41 1 1
MIRT037745 SMG5 SMG5, nonsense mediated mRNA decay factor 1 1
MIRT037746 FAM92A1 family with sequence similarity 92 member A 1 1
MIRT037747 COX1 cytochrome c oxidase subunit I 1 1
MIRT037748 KMT2C lysine methyltransferase 2C 1 1
MIRT037749 YKT6 YKT6 v-SNARE homolog 1 1
MIRT037750 C14orf93 chromosome 14 open reading frame 93 1 1
MIRT037751 VPS29 VPS29, retromer complex component 1 1
MIRT037752 TUBB tubulin beta class I 1 1
MIRT037753 NRCAM neuronal cell adhesion molecule 1 1
MIRT037754 MARCKSL1 MARCKS like 1 1 1
MIRT037755 SEC14L1 SEC14 like lipid binding 1 1 1
MIRT037756 TOP2A DNA topoisomerase II alpha 1 1
MIRT037757 CPSF3 cleavage and polyadenylation specific factor 3 1 1
MIRT037758 SMAP2 small ArfGAP2 1 1
MIRT053062 EYA3 EYA transcriptional coactivator and phosphatase 3 3 1
MIRT054899 NNAT neuronatin 1 1
MIRT255134 SMYD1 SET and MYND domain containing 1 2 4
MIRT317837 CCND3 cyclin D3 2 2
MIRT367648 ARHGAP42 Rho GTPase activating protein 42 2 4
MIRT437386 AKT1 AKT serine/threonine kinase 1 2 1
MIRT437387 CCND1 cyclin D1 2 1
MIRT437388 MMP2 matrix metallopeptidase 2 2 1
MIRT437389 EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2 1
MIRT437390 PARP1 poly(ADP-ribose) polymerase 1 2 1
MIRT437391 BCL2 BCL2, apoptosis regulator 2 1
MIRT437789 CASP2 caspase 2 3 1
MIRT438400 CD274 CD274 molecule 2 1
MIRT438715 CNTFR ciliary neurotrophic factor receptor 3 1
MIRT443875 DDTL D-dopachrome tautomerase like 2 2
MIRT447542 RNF165 ring finger protein 165 2 2
MIRT447609 PCYOX1 prenylcysteine oxidase 1 2 2
MIRT447836 CTIF cap binding complex dependent translation initiation factor 2 2
MIRT448192 FAM168A family with sequence similarity 168 member A 2 2
MIRT448711 KLHL11 kelch like family member 11 2 2
MIRT450177 KLF7 Kruppel like factor 7 2 2
MIRT450310 DRAXIN dorsal inhibitory axon guidance protein 2 2
MIRT460790 VPS37B VPS37B, ESCRT-I subunit 2 2
MIRT466329 THRA thyroid hormone receptor, alpha 2 2
MIRT467608 SLC7A5 solute carrier family 7 member 5 2 2
MIRT471607 PAQR5 progestin and adipoQ receptor family member 5 2 2
MIRT472142 NKIRAS2 NFKB inhibitor interacting Ras like 2 2 4
MIRT476589 G3BP1 G3BP stress granule assembly factor 1 2 4
MIRT486263 LINC00346 long intergenic non-protein coding RNA 346 2 4
MIRT486478 TSC22D1 TSC22 domain family member 1 2 2
MIRT487976 IQSEC2 IQ motif and Sec7 domain 2 2 2
MIRT489426 TUBB2A tubulin beta 2A class IIa 2 2
MIRT500779 TMED4 transmembrane p24 trafficking protein 4 2 6
MIRT501233 SEMA4C semaphorin 4C 2 6
MIRT511043 NRF1 nuclear respiratory factor 1 2 2
MIRT512835 IER3 immediate early response 3 2 2
MIRT513089 USP9X ubiquitin specific peptidase 9, X-linked 2 2
MIRT513541 PRDM2 PR/SET domain 2 2 4
MIRT532389 UMPS uridine monophosphate synthetase 2 2
MIRT535844 MSI2 musashi RNA binding protein 2 2 2
MIRT537890 EDA2R ectodysplasin A2 receptor 2 2
MIRT552768 YIPF6 Yip1 domain family member 6 2 2
MIRT553547 TMEM167A transmembrane protein 167A 2 4
MIRT557227 HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 2 2
MIRT566754 MORF4L1 mortality factor 4 like 1 2 2
MIRT567503 FOXJ3 forkhead box J3 2 2
MIRT568163 CCDC6 coiled-coil domain containing 6 2 2
MIRT570261 PRSS16 protease, serine 16 2 2
MIRT614728 TEAD3 TEA domain transcription factor 3 2 2
MIRT668892 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT691019 CRTC3 CREB regulated transcription coactivator 3 2 2
MIRT697419 ZFP91 ZFP91 zinc finger protein 2 2
MIRT711472 SRD5A1 steroid 5 alpha-reductase 1 2 2
MIRT720188 CMC4 C-X9-C motif containing 4 2 2
MIRT720620 PIANP PILR alpha associated neural protein 2 2
MIRT731442 SMAD3 SMAD family member 3 1 1
MIRT736023 TNF tumor necrosis factor 2 0
MIRT736512 DSPP dentin sialophosphoprotein 3 0
MIRT736513 DMP1 dentin matrix acidic phosphoprotein 1 3 0
MIRT756044 SSRP1 structure specific recognition protein 1 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-708 Doxorubicin approved 31703 Microarray heart 22859947 2012 up-regulated
miR-708 Phenethyl isothiocyanate(PEITC) NULL 16741 Microarray neonatal mice liver 20145010 2010 down-regulated
miR-708 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miR-708 Ascorbate approved 54670067 Microarray Metastatic melanoma cell lines 25202679 2014 up-regualted
miR-708 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miR-708 Ursodeoxycholic acid (UDCA) approved 31401 Microarray rat Liver 20689055 2010 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-708 Tamoxifen 2733525 NSC180973 approved sensitive Low Breast Cancer cell line (MCF-7, T47D)
hsa-mir-708 Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-mir-708 Paclitaxel 36314 NSC125973 approved resistant cell line (W1)
hsa-mir-708 Cisplatin 5460033 NSC119875 approved resistant cell line (W1)
hsa-mir-708 Methotrexate 126941 NSC740 approved sensitive cell line (W1)
hsa-mir-708 Topotecan 60699 NSC609699 approved resistant cell line (W1)
hsa-mir-708 Vincristine 5978 approved sensitive cell line (W1)
hsa-mir-708 Tamoxifen 2733525 NSC180973 approved sensitive cell line (MCF7)
hsa-mir-708 Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)
hsa-miR-708-5p Cisplatin 5460033 NSC119875 approved sensitive High Germ Cell Tumor cell line (NTERA-2)
hsa-miR-708-5p Modified Allic Bfm 2002 Protocol resistant High Childhood Acute Lymphoblastic Leukemia tissue
hsa-miR-708-5p Etoposide 36462 NSC141540 approved sensitive Low Ewing Sarcoma cell line (A673)
hsa-miR-708-5p Doxorubicin 31703 NSC123127 approved sensitive Low Ewing Sarcoma cell line (A673)
hsa-miR-708-5p Gemcitabine 60750 NSC613327 approved resistant High Cholangiocarcinoma cell line (HuCCT1, HuH28)
hsa-miR-708-5p Chemotherapy sensitive High Epithelial Ovarian Cancer tissue
hsa-miR-708-5p Doxorubicin 31703 NSC123127 approved sensitive High Hepatocellular Carcinoma tissue and cell line (HepG2)
hsa-miR-708-5p Doxorubicin 31703 NSC123127 approved sensitive Low Renal Cell Cancer cell line (Caki)
hsa-miR-708-5p Thapsigargin 446378 sensitive Low Renal Cell Cancer cell line (Caki)
hsa-miR-708-5p Cisplatin 5460033 NSC119875 approved sensitive Low Cervical Cancer tissue
hsa-miR-708-5p Tamoxifen 2733525 NSC180973 approved sensitive High Breast Cancer cell line (TAMR4)
hsa-miR-708-5p Aromatase Inhibitor sensitive Low Breast Cancer cell line (MCF-7)
hsa-miR-708-5p Cisplatin 5460033 NSC119875 approved sensitive High Gallbladder Cancer cell line (GBC-SD, NOZ)
hsa-miR-708-5p Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-708-5p Dabrafenib 44462760 NSC764134 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-708-5p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-708-5p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-708-5p Paclitaxel 36314 NSC125973 approved sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-708-5p Cisplatin 5460033 NSC119875 approved sensitive Low Ovarian Cancer cell line (SKOV3, A2780)
hsa-miR-708-5p Cisplatin 5460033 NSC119875 approved resistant Low Urothelial Bladder Cancer cell line (T24)
hsa-miR-708-5p Gemcitabine 60750 NSC613327 approved resistant Low Urothelial Bladder Cancer cell line (T24)
hsa-miR-708-5p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (WM266) (200nM)
hsa-miR-708-5p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (WM266) (2uM)
hsa-miR-708-5p Trametinib 11707110 NSC758246 approved sensitive High Melanoma cell line (WM266) (2uM)
hsa-miR-708-5p Trametinib 11707110 NSC758246 approved sensitive High Melanoma cell line (WM266) (200nM)
hsa-miR-708-5p Cisplatin 5460033 NSC119875 approved sensitive High Non-Small Cell Lung Cancer cell line (A549, HCC827)
hsa-miR-708-5p Gefitinib 123631 NSC715055 approved sensitive High Non-Small Cell Lung Cancer cell line (A549, HCC827)
hsa-miR-708-5p Trail + R428 sensitive Low Renal Cell Cancer cell line (Caki, ACHN, A498, A549, HepG2)
hsa-miR-708-5p Platinum 23939 resistant High High-Grade Serous Ovarian Cancer tissue
hsa-miR-708-5p Cyclophosphamide 2907 NSC26271 approved sensitive High Diffuse Large B-Cell Lymphoma cell line (DB, NU-DHL-1, NU-DUL-1, MC-116, SU-DHL-4, SU-DHL-5, FARAGE, HBL-1, OCI-Ly3, OCI-Ly7, OCI-Ly8, OCI-Ly19, RIVA, SU-DHL-8, U2932)
hsa-miR-708-5p Rituximab resistant High Diffuse Large B-Cell Lymphoma cell line (DB, NU-DHL-1, NU-DUL-1, MC-116, SU-DHL-4, SU-DHL-5, FARAGE, HBL-1, OCI-Ly3, OCI-Ly7, OCI-Ly8, OCI-Ly19, RIVA, SU-DHL-8, U2932)
hsa-miR-708-5p Doxorubicin 31703 NSC123127 approved sensitive High Diffuse Large B-Cell Lymphoma cell line (DB, NU-DHL-1, NU-DUL-1, MC-116, SU-DHL-4, SU-DHL-5, FARAGE, HBL-1, OCI-Ly3, OCI-Ly7, OCI-Ly8, OCI-Ly19, RIVA, SU-DHL-8, U2932)
hsa-miR-708-5p Vincristine 5978 approved sensitive High Diffuse Large B-Cell Lymphoma cell line (DB, NU-DHL-1, NU-DUL-1, MC-116, SU-DHL-4, SU-DHL-5, FARAGE, HBL-1, OCI-Ly3, OCI-Ly7, OCI-Ly8, OCI-Ly19, RIVA, SU-DHL-8, U2932)
hsa-miR-708-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (W1)
hsa-miR-708-5p Cisplatin 5460033 NSC119875 approved sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-708-5p Temozolomide 5394 NSC362856 approved sensitive cell line (U251)
hsa-miR-708-5p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-708-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-708-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-miR-708-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-708-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-708-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (SKVO3ip1)
hsa-miR-708-5p Paclitaxel 36314 NSC125973 approved resistant cell line (HeyA8)
hsa-miR-708-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (BAS)
hsa-miR-708-5p Doxorubicin 31703 NSC123127 approved sensitive cell line (BAS)
hsa-miR-708-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-708-5p Tamoxifen+Fulvestrant resistant cell line (LCC9)
hsa-miR-708-5p Ethanol+Tamoxifen sensitive cell line (LY2)
hsa-miR-708-5p Methotrexate 126941 NSC740 approved resistant cell line (HT29)
hsa-miR-708-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (RPMI2650)
hsa-miR-708-5p Gemcitabine 60750 NSC613327 approved resistant cell line (HuH28)
hsa-miR-708-5p Tamoxifen 2733525 NSC180973 approved sensitive cell line (TamR4)
hsa-miR-708-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (IGROV-1)
hsa-miR-708-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-708-5p Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)
hsa-miR-708-5p Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)
hsa-miR-708-5p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)
hsa-miR-708-5p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide/Methotrexate/Gemcitabine resistant cell line (Bats-72)

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