miRTarBase - #MIRT006412


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pre-miRNA Information
pre-miRNA hsa-mir-708   
Genomic Coordinates chr11: 79402022 - 79402109
Synonyms MIRN708, hsa-mir-708, MIR708
Description Homo sapiens miR-708 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-708-3p
Sequence 57| CAACUAGACUGUGAGCUUCUAG |78
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 2 11 - 79402052 29233923 MiREDiBase
A-to-I 3 11 - 79402051 29233923 MiREDiBase
A-to-I 6 11 - 79402048 29233923 MiREDiBase
A-to-I 21 11 - 79402033 29233923 MiREDiBase
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN30529329 6 COSMIC
COSN31662869 7 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1433496718 2 dbSNP
rs770860828 5 dbSNP
rs1022837721 6 dbSNP
rs1175971857 8 dbSNP
rs760802299 10 dbSNP
rs1410180708 22 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol N4BP1   
Synonyms -
Description NEDD4 binding protein 1
Transcript NM_153029   
Expression
Putative miRNA Targets on N4BP1
3'UTR of N4BP1
(miRNA target sites are highlighted)		 
>N4BP1|NM_153029|3'UTR
   1 AGATTGTGCTGAGCGCTGAGCTTGCGCTCAGGGCTGGCTGATCAAACTCAAGCTCACACCTGTACCTGATGGGAATGAAC
  81 ATAATGTGAAGAAACTTATTTCCCAGTGTAAACGCAGTTGTACAGAAAAAAAATGTTTTGGGTATAAATCTGGGTTTTCA
 161 AAACCAGCTTTTTTCTATATATAAATTATGCTGCTATTACAGATTTAACATTTTCTGTTAAAGGAAAGTCTACATTTTCT
 241 GCCTGTTCAGAACTGTTTAATAGCAGTTACTCTTGAGTGTATTTACCTTTTTATGTTTTTTAAACTATTTTCCTTAAAGC
 321 CGAAAATATTGACAAATGGATATGGTTAGCCTTTATAAATAAATAAAAAAAAAAGTGTTGCTTTCTTAAGGAAAGCAAGA
 401 CGTCTTAAAGTATATTTTCTTGAGATGAGTATGTCCCATCACTACCATGAAGTGTGCTCACCCTTCCAGCCTCCTCTGCC
 481 CTCACCCCCGGAGTTAAAGTGGGTAAGAGTTGGTTTGTTCTGCAGTCTTTGGTTGGAGTGTTGTGAAAGTGGACCCGCGG
 561 TGCCACTAGATGGCACTTGGTGCCTAGCCATGGTGAATGACCAGGGCGAAGTTAGTCTCACAGAATACCAGGGCTAGAAG
 641 ACATCGTGGAGCCCATGGAGTCCCACCCTCCTTCCCCCTTCCACCCTGCGCAAAAGGGGACGGCCCAGTGTGCACGCCGT
 721 CCGGCCATGCCCACAGCCACAGCCACAGCTGAGGAGTGGCCGGGCAGGCAGCAGGCTCCCCAGCCAGGGCTTGACACGCC
 801 CACAGTCAGGGGCCTCCACATGCCTGGCCTGGCTCTGGAAGTCACGTCTTAGCTTCTGAACACCGTAGCGGGTTATGAGG
 881 AAGTTTAATGAAGAGCCCGGTCACTGTGGCCATCTTGTGTCCCCAACTGCAGGAGACGCCCTGATGTGGAGTTTGTACAG
 961 CTTTGCCAAAAAATGGTTTTCTATTCTCAAAAGTGACCCAAGCCAATAAATAGCATTAGTAGCTTCTGTGGGGGGATCCC
1041 AGAGCCCCTGTATTTATTTTCCCTGTGTTTGTCTCTAGTGTCCTCCTAAACAGCCTTTCCTGTGAGTCTTTCTCAGAATT
1121 GATATCTTAATATTGTCTGTTCTAGGTGTTGCCCAAATTCAGTGTCAGTGAAGTTCTTTTCCTGGGCAATCTTAACATCT
1201 TTACTCTTATTGTCTGGACCTTCAAAGGGCTTTGTATTTTACACCTGCGCCCCCAGGCTGCTCACAGTCGGCTTGCTGCC
1281 TGTCCTGCCTGTCCGGATCTTGTCTCCTAGTCCTGAGGAGCGGAGGCTGAGAACTCAGTGCTGGTTTGTAAATGGTGAGG
1361 GGACTTGGGGGCATCCCAGAGTGCTCCCTCCAGGCCTGCTTCTTGGTTTTGTTTGATCACTGCGTTCTTCAAGGGATGAA
1441 TCCAGAGCCCTCCATGAGGCCAAGCTTGTCCTTCAATCATGTTTCCTCTCAGATGCGTCCGTGATGCCTCCTAATGTGGA
1521 ACTGGTTGTCCATTGTTTGGGCCTATGGCCAAGTCACCCAGCTGTGGAAGCAGAGGTAGAAGACGAGGCCAGCCAGGAGG
1601 GCGACTTCAGTCACAGCTCCCATGCCTCAGCTTTGTACCTGTTTTCAAAAGCACAACTGAGGTGTGCGGGCTGGAGCTGT
1681 CTTGCAGTGATTCTGGCCTTCTGGCTCATGGTTCAGTCCAGCAGCCTGGCTGACCCACTATTTCTCCTCTGCTTCAGAGG
1761 AAACCCAGGAAATGCCCTTACTGCCAGGCTGAGTCTCCACCCATGCTGGTTGGTGCTGGCTAGGCTGAGGGGGCCACCAC
1841 TTTTCCTGGCTAGAAGCTACTTGACCTTTGATGTTTGAGTTCTGTAAGTCTTCGTGTTCTGACTTACTGCTTCAGAGGGA
1921 TTGGCCTGTCCCCTTTCCCTTTCTCGGCTATGGGAAGGAAGGATTGCTCATTGGTTGCCTTCATCAGTTACAGCATGAGA
2001 CGGAATTCATCATTCCTTCCGAAACCCCTGATATTTAATATTTAATATTTAAAAACCCAAATTATCAAACCATTAAGAAC
2081 TCATTACTGGTTCTCAGCCTCCTCCAGTACTAGCCTCAGTGTGGCTGCTGCATAAGTATCTGTAGCCTGTCTACCTCCTG
2161 CAGTGGGGCCGCTCGCCTCTTCCCTGTCTACTGCTCAGGCTCTCCCACTTCGTGGCATCCATGTAAAGTAGGTGGCAGGG
2241 CAGAGATGTCACTCTCATTCAACAGGGAGGATGTCTGTTGCTCAGAGAGGTTGTCCTGAGGGGCTGGGTGATTCCTGGGC
2321 CTACATTCTTCCCGAGGCTCCAGGCCGCTGTCTCTGGAAGTAAAAGAGCCTTGTCTGACCTTAATGCAAGCAGTCTGTTT
2401 GAACCCCTGTAGGCTGCATTCAGGAGACAGAAGGTGTCTGGGCCATCCTGGGCGGCCGGTCAGCGTTGCTAGGCAGGCTC
2481 GGCTGTCTGGCCGGGACTTGGGCCTGGGTGGCTTTTGAGACCAGTGAAGAAGGGAGAGCCGGCCTCATGCCGATGCGGCT
2561 TGTGGCACGGCTGGGATGTGAGGGAGGACTCAGATCTACACACAGAAACCCCTCTTCTCCCCGCCCTCCCCCAGCTCCTA
2641 CCTGCCTCCCACGCCTCAGGTGTGGCTGCCTGTGGGACCATCCCCCAACCCCTTTCCTCGCACCTCCTTGTCCTCACCCA
2721 GTTCCTGCAGTGTCTCTGACCCACGCCTCCCGCCTCCTGGCCGACTTGCCCAGGAGGTGTCTCTGGCTCACCTCCGTCTG
2801 TTCATCACCTTCCTCCCCAGTGTTTCCACTTATCTTGGATGTTTTAGATTGAAACAGCCTGATTCCCGGAAGAATCCTCT
2881 TCATTCATTGCTAGTGCTTCCCCTCACCTCCCACTCTCCACTTCCCAGTTTGCAAATGTGGCTTTCGCCCACCAAGTGAA
2961 AGCGGACTGAGAGCAGCCCTTGGGGACGGCCCGGTGCCTGGCTGCAAGGCCGCGCTGGGGCTCTGTCTTGGTGCACATGG
3041 CTTGACCGGACTTTCCCTGCTTCCCACCACTTCCCTCACTCCCAGACCTCCCTCATTCTTTTTGTCTCTTCTTTTTGCCT
3121 AAAGCCAGTCCTTAACACCCTATTCTTCCTCTGCAGGTGGCTTGCAGACTTTTCCCCACCTTTGGGGCTCGTGGTGGTGG
3201 AGAGGGCAGCTGGTGTTAAGAATGTAGGTTACCGGGCATGACCCGGCAGATGCTTGCCCAGTAGTTCTGGAGGAAGGCCC
3281 GGGAATCTGCAAATGAGCGCATTCCCCAGGCAGTTCCCATGCAGGTGATCCACGGACCACATGTTGAGAAACTGCAGTCA
3361 CCCTTAGGGCCACACCGTCCCTCTCCTCGCTGTCCCCTCTCTGTAGTGACTGGCCCTGACCTTCAGGAGTGCACTTTCCA
3441 CTCTACCAGGAAGCCCTATGACATCCTCAGGCTCCCCAGACCTGCAGCTTGCATGGGGCCCCTCCCTTCTTCCACACCCA
3521 CCCTCCGTATGGTCCCCTGCTCTGCCCTCGTGCTTTGCTGGCCCCTGCCCGCTACTCCCACTCTCAGACACCCAGGGGTG
3601 GTGGGCCCTAACTGGCTGGCCCCTCCCAGCGCTGCCCTCTGCCGTCCAGATGCTGCAGTGTGGCCAGATTTACCTTCCAG
3681 TAACATACTTCTAGTCACCCCTCCTCCTGCGAAGTGATCTGCAGTGGCTGTTTGACCAGACCACAAAGTTCACATCTCCT
3761 GAGCTTAGTGTCCGTGGCTGTCCACCTCCCAGCCATACTTGACTGTCCCCAAACTCTCCCTGCAGCCACATGTTTCCCAT
3841 GACCTGTGGGCTCTGCAGATGGACCTCTCTCCGCTAGAGATGCCCTTCTCCCAAATGGCTTCCCTCCTGGAAGGCCCAGC
3921 CTGAGTCCTCGTCTCCTTTCCAGTGCTTCTGCCAGAAGCATCCCCATGATGTTGTGACCGCACAGCACTTTGTGTCTCGC
4001 TTTGAGCACTTGCCACTCTGGCTGGTGCTGCTGCCACTGATTGTGTACTGTCTTGCTGCCCTTTCTAGACTGTGAGCTCC
4081 TCGTGGGCAGGGACCGCCTGTGTTCTCTGTATTTCCCACGGCGCCTAGCACAGTGCCTTGCACTTGATAGGTGCTTAATA
4161 AATGTCTGCTCAACTGAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gaUCUUCGAGUGUCAGAUCAac 5'
            || | | :||  ||||||  
Target 5' ccAGTAACATAC-TTCTAGTca 3'
 3677 - 3697 131.00 -7.10
2 
miRNA  3' gaucuuCGAGUGUCAGAUCAac 5'
                |:|:::  ||||||  
Target 5' ccctgtGTTTGT-CTCTAGTgt 3'
 1061 - 1081 123.00 -5.40
3 
miRNA  3' gaucuuCGAG-UGUC--AGAUCAAc 5'
                |:|| :|||  |:|:||| 
Target 5' tggtttGTTCTGCAGTCTTTGGTTg 3'
 511 - 535 122.00 -16.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31486436 11 COSMIC
COSN31541301 31 COSMIC
COSN30513173 59 COSMIC
COSN30495857 66 COSMIC
COSN31508384 94 COSMIC
COSN31578999 125 COSMIC
COSN31599928 129 COSMIC
COSN31571447 310 COSMIC
COSN20112853 365 COSMIC
COSN22601541 559 COSMIC
COSN30538642 583 COSMIC
COSN27062293 718 COSMIC
COSN23040166 868 COSMIC
COSN26538085 999 COSMIC
COSN31523742 1020 COSMIC
COSN29882032 1137 COSMIC
COSN15660764 1490 COSMIC
COSN31961201 1669 COSMIC
COSN17595682 1946 COSMIC
COSN21645943 2365 COSMIC
COSN22733965 2460 COSMIC
COSN21319961 2517 COSMIC
COSN15963465 2700 COSMIC
COSN24952877 2744 COSMIC
COSN24567041 2781 COSMIC
COSN21097649 2938 COSMIC
COSN28831396 3387 COSMIC
COSN16036767 3398 COSMIC
COSN2520834 3517 COSMIC
COSN8500389 3784 COSMIC
COSN1699035 3941 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1252841475 2 dbSNP
rs1296028702 5 dbSNP
rs778343070 8 dbSNP
rs758750465 12 dbSNP
rs753035562 13 dbSNP
rs11866667 14 dbSNP
rs372613628 15 dbSNP
rs570902054 18 dbSNP
rs1465567790 21 dbSNP
rs143735071 24 dbSNP
rs760739461 25 dbSNP
rs750417433 26 dbSNP
rs767432062 29 dbSNP
rs761517518 30 dbSNP
rs374398437 33 dbSNP
rs199782053 36 dbSNP
rs1408303743 41 dbSNP
rs762745952 43 dbSNP
rs775254121 49 dbSNP
rs1325437341 51 dbSNP
rs1370042535 53 dbSNP
rs1384421387 56 dbSNP
rs1431134742 58 dbSNP
rs1271891340 62 dbSNP
rs958017324 73 dbSNP
rs1032326222 75 dbSNP
rs1359701001 78 dbSNP
rs999394111 80 dbSNP
rs1182429368 90 dbSNP
rs966634631 91 dbSNP
rs1248341689 99 dbSNP
rs1176059811 107 dbSNP
rs765563693 113 dbSNP
rs780825866 114 dbSNP
rs886107696 120 dbSNP
rs1219849190 127 dbSNP
rs1475406031 133 dbSNP
rs1047899553 134 dbSNP
rs1189261432 134 dbSNP
rs866777172 134 dbSNP
rs949155782 135 dbSNP
rs1008066797 138 dbSNP
rs889511772 139 dbSNP
rs111733638 141 dbSNP
rs1401079777 142 dbSNP
rs1049507170 144 dbSNP
rs995284127 145 dbSNP
rs1319977846 146 dbSNP
rs1057279728 150 dbSNP
rs562047580 152 dbSNP
rs937532753 164 dbSNP
rs749637417 174 dbSNP
rs768052219 177 dbSNP
rs1230877516 180 dbSNP
rs746465465 184 dbSNP
rs1350863300 198 dbSNP
rs779874961 200 dbSNP
rs1282675224 210 dbSNP
rs548637554 223 dbSNP
rs1446751672 239 dbSNP
rs1212286244 248 dbSNP
rs1260166805 250 dbSNP
rs1484750358 253 dbSNP
rs202150105 260 dbSNP
rs979000244 261 dbSNP
rs80099509 266 dbSNP
rs1364718209 270 dbSNP
rs1157044961 275 dbSNP
rs1158869197 275 dbSNP
rs1455155160 276 dbSNP
rs940887903 281 dbSNP
rs1361953086 282 dbSNP
rs1418847185 284 dbSNP
rs913228734 294 dbSNP
rs1480460955 295 dbSNP
rs1377122296 296 dbSNP
rs1270497350 303 dbSNP
rs908126070 305 dbSNP
rs989260468 313 dbSNP
rs954800832 318 dbSNP
rs1030861519 320 dbSNP
rs370169012 321 dbSNP
rs1046975778 322 dbSNP
rs750256086 329 dbSNP
rs374923523 333 dbSNP
rs1016150706 337 dbSNP
rs949592483 339 dbSNP
rs916760926 343 dbSNP
rs1006149217 349 dbSNP
rs778656505 355 dbSNP
rs1262002804 356 dbSNP
rs1207224874 360 dbSNP
rs1485112403 364 dbSNP
rs958153357 365 dbSNP
rs562330817 368 dbSNP
rs377348736 374 dbSNP
rs1232473329 375 dbSNP
rs1396452663 375 dbSNP
rs3833064 375 dbSNP
rs796461419 375 dbSNP
rs1438891091 381 dbSNP
rs1173965762 385 dbSNP
rs545721341 401 dbSNP
rs896222371 402 dbSNP
rs978072172 407 dbSNP
rs1325751796 411 dbSNP
rs1171894460 414 dbSNP
rs1281516962 420 dbSNP
rs1396652971 427 dbSNP
rs532271708 428 dbSNP
rs966561657 429 dbSNP
rs1326480257 431 dbSNP
rs1375614434 442 dbSNP
rs1019549341 444 dbSNP
rs1008451585 448 dbSNP
rs111383244 449 dbSNP
rs906041812 451 dbSNP
rs1233211823 452 dbSNP
rs1252386315 454 dbSNP
rs1341593837 459 dbSNP
rs1028599089 462 dbSNP
rs1272572800 465 dbSNP
rs756384937 471 dbSNP
rs995253055 474 dbSNP
rs1195724966 482 dbSNP
rs553062956 489 dbSNP
rs933330000 490 dbSNP
rs880399 491 dbSNP
rs1373532517 493 dbSNP
rs1476110633 499 dbSNP
rs1165595469 500 dbSNP
rs1036659451 502 dbSNP
rs1398904667 511 dbSNP
rs1003898764 515 dbSNP
rs1461702347 522 dbSNP
rs1327468911 530 dbSNP
rs1392805103 535 dbSNP
rs879318329 537 dbSNP
rs886660929 538 dbSNP
rs539849142 556 dbSNP
rs767722107 557 dbSNP
rs574345729 558 dbSNP
rs1335512754 559 dbSNP
rs1215838854 564 dbSNP
rs1271450624 568 dbSNP
rs554383620 577 dbSNP
rs1208948100 582 dbSNP
rs950594682 583 dbSNP
rs1173549388 588 dbSNP
rs35633615 590 dbSNP
rs1430298291 591 dbSNP
rs544279833 593 dbSNP
rs1013220015 597 dbSNP
rs936723550 601 dbSNP
rs1479843945 607 dbSNP
rs960669120 608 dbSNP
rs111417610 614 dbSNP
rs1427081653 616 dbSNP
rs978042378 619 dbSNP
rs55950580 623 dbSNP
rs1289873184 624 dbSNP
rs1204855240 625 dbSNP
rs879550174 640 dbSNP
rs527798684 642 dbSNP
rs556789756 645 dbSNP
rs758395295 646 dbSNP
rs892019236 647 dbSNP
rs752888707 649 dbSNP
rs1340180060 650 dbSNP
rs1321287192 653 dbSNP
rs767035127 654 dbSNP
rs1272122332 656 dbSNP
rs1261162438 661 dbSNP
rs986717548 668 dbSNP
rs954139731 675 dbSNP
rs1028150487 676 dbSNP
rs1053799039 682 dbSNP
rs973903472 684 dbSNP
rs1294512532 687 dbSNP
rs35793171 687 dbSNP
rs1253663382 689 dbSNP
rs1422943363 692 dbSNP
rs1453104035 696 dbSNP
rs540174490 699 dbSNP
rs763534774 701 dbSNP
rs138897573 702 dbSNP
rs943430815 708 dbSNP
rs1015365277 714 dbSNP
rs554401062 715 dbSNP
rs369163945 716 dbSNP
rs1416714254 718 dbSNP
rs533962968 719 dbSNP
rs866905154 721 dbSNP
rs568410894 722 dbSNP
rs1013828345 723 dbSNP
rs534698051 725 dbSNP
rs755143910 728 dbSNP
rs1285230621 730 dbSNP
rs144562714 730 dbSNP
rs984609743 749 dbSNP
rs1235280288 750 dbSNP
rs1482628982 750 dbSNP
rs950541578 750 dbSNP
rs371877606 751 dbSNP
rs1252177389 759 dbSNP
rs1055182886 761 dbSNP
rs1438461578 762 dbSNP
rs114796388 770 dbSNP
rs1194164090 771 dbSNP
rs1437196173 772 dbSNP
rs1172281695 777 dbSNP
rs1033762762 778 dbSNP
rs1001850483 780 dbSNP
rs903920452 782 dbSNP
rs1444328623 784 dbSNP
rs1246372207 786 dbSNP
rs1308342303 795 dbSNP
rs1371417092 797 dbSNP
rs531809570 798 dbSNP
rs1276355780 801 dbSNP
rs1311134283 810 dbSNP
rs1384781262 814 dbSNP
rs1252714193 816 dbSNP
rs945476697 817 dbSNP
rs1456213292 818 dbSNP
rs762166363 820 dbSNP
rs570569965 821 dbSNP
rs1455838609 824 dbSNP
rs1011676821 832 dbSNP
rs113535394 844 dbSNP
rs551945313 845 dbSNP
rs1330248417 846 dbSNP
rs1172553436 850 dbSNP
rs1053340878 851 dbSNP
rs532136024 864 dbSNP
rs902132030 865 dbSNP
rs1394967852 867 dbSNP
rs552062748 870 dbSNP
rs560036106 877 dbSNP
rs796406028 893 dbSNP
rs189132859 897 dbSNP
rs1049190167 898 dbSNP
rs537283403 899 dbSNP
rs1197677972 905 dbSNP
rs879702493 906 dbSNP
rs1273373599 907 dbSNP
rs1470109155 917 dbSNP
rs1179698306 923 dbSNP
rs774947902 926 dbSNP
rs1188767289 931 dbSNP
rs7197732 937 dbSNP
rs992046592 938 dbSNP
rs1165934610 942 dbSNP
rs1361329338 943 dbSNP
rs1406902359 962 dbSNP
rs1289403553 965 dbSNP
rs1321399819 967 dbSNP
rs560916654 969 dbSNP
rs1431477732 974 dbSNP
rs1290544911 975 dbSNP
rs1351230952 976 dbSNP
rs1337791852 977 dbSNP
rs895378981 983 dbSNP
rs1439335771 992 dbSNP
rs1293560746 998 dbSNP
rs1336425492 1002 dbSNP
rs1033908589 1007 dbSNP
rs1289663068 1015 dbSNP
rs1317887803 1019 dbSNP
rs1349392775 1023 dbSNP
rs1001103375 1029 dbSNP
rs1406452138 1030 dbSNP
rs904011951 1031 dbSNP
rs980377734 1033 dbSNP
rs967706214 1036 dbSNP
rs544019351 1045 dbSNP
rs1401679711 1046 dbSNP
rs112671145 1052 dbSNP
rs1042575284 1056 dbSNP
rs987859356 1057 dbSNP
rs36125839 1064 dbSNP
rs1160387775 1065 dbSNP
rs1358499887 1077 dbSNP
rs945474611 1078 dbSNP
rs536918296 1079 dbSNP
rs1469660371 1080 dbSNP
rs1341704257 1082 dbSNP
rs745791559 1091 dbSNP
rs1351858821 1094 dbSNP
rs575398383 1095 dbSNP
rs997717755 1098 dbSNP
rs902080075 1099 dbSNP
rs1430152026 1102 dbSNP
rs1017882887 1108 dbSNP
rs1007539942 1109 dbSNP
rs887777691 1110 dbSNP
rs1201848719 1114 dbSNP
rs183997007 1119 dbSNP
rs1268456426 1122 dbSNP
rs191517090 1126 dbSNP
rs1174177141 1131 dbSNP
rs1056689242 1139 dbSNP
rs1335933355 1142 dbSNP
rs1448508096 1146 dbSNP
rs1220508173 1151 dbSNP
rs766662339 1176 dbSNP
rs1307584690 1178 dbSNP
rs1376623198 1182 dbSNP
rs1235745041 1183 dbSNP
rs921293561 1186 dbSNP
rs577487150 1189 dbSNP
rs1199901255 1190 dbSNP
rs1286235763 1200 dbSNP
rs548083428 1202 dbSNP
rs941295084 1204 dbSNP
rs1196947029 1205 dbSNP
rs1236205972 1206 dbSNP
rs908365034 1208 dbSNP
rs1438832871 1210 dbSNP
rs982617758 1211 dbSNP
rs971130386 1215 dbSNP
rs368301343 1217 dbSNP
rs757015590 1220 dbSNP
rs529211481 1225 dbSNP
rs1396555665 1236 dbSNP
rs914902988 1248 dbSNP
rs991144333 1249 dbSNP
rs1224824312 1250 dbSNP
rs1400045493 1255 dbSNP
rs1442014093 1258 dbSNP
rs958604818 1269 dbSNP
rs1343210399 1270 dbSNP
rs1292603220 1275 dbSNP
rs1032665693 1287 dbSNP
rs1320084909 1291 dbSNP
rs781302562 1294 dbSNP
rs1257595301 1295 dbSNP
rs1347352397 1296 dbSNP
rs1214041485 1298 dbSNP
rs1316834457 1302 dbSNP
rs1269178413 1303 dbSNP
rs1457236081 1308 dbSNP
rs1449835746 1318 dbSNP
rs968305925 1321 dbSNP
rs150262007 1322 dbSNP
rs1010154185 1334 dbSNP
rs1373206344 1337 dbSNP
rs1478483818 1354 dbSNP
rs1178598158 1355 dbSNP
rs1168100611 1356 dbSNP
rs1479516810 1362 dbSNP
rs746015816 1365 dbSNP
rs1422421223 1368 dbSNP
rs1462313053 1370 dbSNP
rs1017828970 1371 dbSNP
rs891180951 1375 dbSNP
rs1051601708 1379 dbSNP
rs768133597 1387 dbSNP
rs996964217 1388 dbSNP
rs899830884 1399 dbSNP
rs1319536393 1400 dbSNP
rs888062803 1413 dbSNP
rs866589528 1418 dbSNP
rs1475601497 1423 dbSNP
rs1038411685 1424 dbSNP
rs1213400919 1430 dbSNP
rs142618007 1450 dbSNP
rs1267066007 1464 dbSNP
rs1353978186 1471 dbSNP
rs1263711376 1474 dbSNP
rs1263730465 1478 dbSNP
rs908459979 1479 dbSNP
rs1190813807 1491 dbSNP
rs1046869439 1496 dbSNP
rs1475353056 1497 dbSNP
rs949937894 1500 dbSNP
rs1367144710 1506 dbSNP
rs917120398 1507 dbSNP
rs991631806 1525 dbSNP
rs1300125673 1527 dbSNP
rs958488168 1532 dbSNP
rs1214860878 1533 dbSNP
rs554945901 1535 dbSNP
rs1268732121 1538 dbSNP
rs138868971 1540 dbSNP
rs939142548 1545 dbSNP
rs1418388921 1547 dbSNP
rs905042636 1560 dbSNP
rs925614058 1563 dbSNP
rs1356174249 1571 dbSNP
rs1398067972 1578 dbSNP
rs187435686 1584 dbSNP
rs915180961 1585 dbSNP
rs1442207518 1591 dbSNP
rs968233769 1598 dbSNP
rs1339298922 1600 dbSNP
rs1355826396 1602 dbSNP
rs1214318439 1603 dbSNP
rs1284769334 1614 dbSNP
rs1021174761 1615 dbSNP
rs374371592 1619 dbSNP
rs1009848553 1621 dbSNP
rs1253554777 1624 dbSNP
rs1423622893 1625 dbSNP
rs1183051336 1626 dbSNP
rs1382525390 1627 dbSNP
rs1158561367 1630 dbSNP
rs1171392018 1630 dbSNP
rs955708207 1632 dbSNP
rs935025536 1640 dbSNP
rs1467590278 1646 dbSNP
rs1029867744 1648 dbSNP
rs1401706101 1651 dbSNP
rs370502581 1656 dbSNP
rs899925384 1659 dbSNP
rs1038339037 1662 dbSNP
rs1378829954 1664 dbSNP
rs184242566 1667 dbSNP
rs751642569 1668 dbSNP
rs886997057 1682 dbSNP
rs1047410427 1685 dbSNP
rs1211562419 1686 dbSNP
rs372223785 1687 dbSNP
rs1482748909 1697 dbSNP
rs1198882441 1698 dbSNP
rs1448665154 1702 dbSNP
rs1243652664 1707 dbSNP
rs1178575350 1713 dbSNP
rs1185385003 1717 dbSNP
rs966165420 1718 dbSNP
rs3760017 1723 dbSNP
rs986335912 1728 dbSNP
rs1462746530 1730 dbSNP
rs766557599 1740 dbSNP
rs551119151 1741 dbSNP
rs759044617 1756 dbSNP
rs937060331 1757 dbSNP
rs925709684 1761 dbSNP
rs146928987 1774 dbSNP
rs1220848251 1775 dbSNP
rs1204626865 1777 dbSNP
rs945701570 1798 dbSNP
rs993885390 1800 dbSNP
rs1218878807 1808 dbSNP
rs1259518193 1810 dbSNP
rs867104067 1811 dbSNP
rs1308831488 1813 dbSNP
rs1198353590 1819 dbSNP
rs962074794 1821 dbSNP
rs1489777670 1832 dbSNP
rs560438346 1838 dbSNP
rs750976666 1840 dbSNP
rs1424618913 1841 dbSNP
rs1478154291 1855 dbSNP
rs765778276 1865 dbSNP
rs546605978 1866 dbSNP
rs1228067130 1874 dbSNP
rs1421699353 1879 dbSNP
rs1463886307 1882 dbSNP
rs529995047 1884 dbSNP
rs762103765 1885 dbSNP
rs1384057223 1886 dbSNP
rs988794589 1887 dbSNP
rs905327125 1893 dbSNP
rs955680278 1894 dbSNP
rs1317744123 1897 dbSNP
rs1244663669 1903 dbSNP
rs1291657380 1905 dbSNP
rs1010721855 1915 dbSNP
rs1400037152 1919 dbSNP
rs1030210344 1931 dbSNP
rs1052381622 1939 dbSNP
rs1315731460 1945 dbSNP
rs1039341 1946 dbSNP
rs1323864340 1950 dbSNP
rs1220015147 1951 dbSNP
rs370403106 1952 dbSNP
rs1488674741 1957 dbSNP
rs1195870115 1963 dbSNP
rs964100540 1964 dbSNP
rs1477657923 1965 dbSNP
rs1182656485 1970 dbSNP
rs1414278703 1987 dbSNP
rs1406812231 1992 dbSNP
rs763692021 1995 dbSNP
rs1017042965 1996 dbSNP
rs74372789 2001 dbSNP
rs760351561 2002 dbSNP
rs1025683036 2009 dbSNP
rs1337766765 2012 dbSNP
rs1168249175 2016 dbSNP
rs774057803 2020 dbSNP
rs775037861 2021 dbSNP
rs1226921229 2026 dbSNP
rs895743317 2030 dbSNP
rs1055998011 2034 dbSNP
rs986270969 2041 dbSNP
rs1355103386 2048 dbSNP
rs757305050 2053 dbSNP
rs952210565 2053 dbSNP
rs937195960 2055 dbSNP
rs1487972573 2056 dbSNP
rs920807542 2058 dbSNP
rs1239392130 2060 dbSNP
rs1473669393 2065 dbSNP
rs972351039 2067 dbSNP
rs1165376467 2077 dbSNP
rs1421920749 2078 dbSNP
rs1440310263 2080 dbSNP
rs1160369124 2088 dbSNP
rs1255394960 2095 dbSNP
rs771565605 2096 dbSNP
rs1481342693 2098 dbSNP
rs189200899 2101 dbSNP
rs1399541585 2104 dbSNP
rs564996358 2105 dbSNP
rs1334432317 2117 dbSNP
rs1360483928 2118 dbSNP
rs1445323621 2124 dbSNP
rs1314876262 2125 dbSNP
rs1042766941 2128 dbSNP
rs945837299 2138 dbSNP
rs912880233 2147 dbSNP
rs1307630367 2151 dbSNP
rs987162135 2161 dbSNP
rs1353117294 2162 dbSNP
rs1201060656 2165 dbSNP
rs1280803028 2169 dbSNP
rs934196730 2170 dbSNP
rs922896294 2171 dbSNP
rs975549026 2174 dbSNP
rs763724067 2175 dbSNP
rs1308365491 2177 dbSNP
rs1039340 2178 dbSNP
rs1017138601 2179 dbSNP
rs1307648515 2190 dbSNP
rs386790520 2191 dbSNP
rs1405840001 2192 dbSNP
rs1010670950 2194 dbSNP
rs1172703700 2200 dbSNP
rs1426621252 2202 dbSNP
rs1412462579 2207 dbSNP
rs577550906 2211 dbSNP
rs1367692249 2228 dbSNP
rs984202981 2239 dbSNP
rs183841382 2241 dbSNP
rs1449411530 2245 dbSNP
rs1329937773 2252 dbSNP
rs560718571 2254 dbSNP
rs540616730 2255 dbSNP
rs1456230533 2257 dbSNP
rs1052745976 2267 dbSNP
rs1223147667 2270 dbSNP
rs1258880496 2279 dbSNP
rs1026034853 2282 dbSNP
rs1367775060 2306 dbSNP
rs1159809055 2307 dbSNP
rs1236109833 2310 dbSNP
rs1014261410 2315 dbSNP
rs1437203744 2316 dbSNP
rs1199477169 2325 dbSNP
rs895700956 2333 dbSNP
rs1034285354 2334 dbSNP
rs528544383 2335 dbSNP
rs1001429822 2337 dbSNP
rs575068258 2346 dbSNP
rs1466844564 2347 dbSNP
rs770863361 2352 dbSNP
rs1396221554 2361 dbSNP
rs749078244 2369 dbSNP
rs1009905348 2370 dbSNP
rs1326042107 2382 dbSNP
rs1040695436 2389 dbSNP
rs1270634605 2390 dbSNP
rs1404367625 2394 dbSNP
rs1279099312 2395 dbSNP
rs891545788 2404 dbSNP
rs1051843169 2406 dbSNP
rs1320328405 2413 dbSNP
rs1216994533 2415 dbSNP
rs933014389 2417 dbSNP
rs942358431 2424 dbSNP
rs751752916 2434 dbSNP
rs889517916 2434 dbSNP
rs1210366985 2436 dbSNP
rs1048177250 2449 dbSNP
rs376629070 2453 dbSNP
rs551563688 2454 dbSNP
rs1488385927 2457 dbSNP
rs942972763 2458 dbSNP
rs930767180 2464 dbSNP
rs554925056 2465 dbSNP
rs1165541077 2469 dbSNP
rs1241889840 2480 dbSNP
rs547113152 2481 dbSNP
rs775289114 2492 dbSNP
rs928233966 2493 dbSNP
rs1295045538 2495 dbSNP
rs982048271 2497 dbSNP
rs969376760 2505 dbSNP
rs1224204554 2510 dbSNP
rs575198901 2511 dbSNP
rs1357244800 2517 dbSNP
rs1281645840 2531 dbSNP
rs989532173 2540 dbSNP
rs918699497 2541 dbSNP
rs993210571 2542 dbSNP
rs375310011 2544 dbSNP
rs538725183 2546 dbSNP
rs566596378 2548 dbSNP
rs958396341 2552 dbSNP
rs1030830918 2554 dbSNP
rs999787641 2555 dbSNP
rs3743778 2556 dbSNP
rs1019562820 2557 dbSNP
rs1386377353 2564 dbSNP
rs1157686810 2565 dbSNP
rs1480490628 2566 dbSNP
rs1430946591 2567 dbSNP
rs1001397206 2568 dbSNP
rs1432962264 2569 dbSNP
rs1262936988 2580 dbSNP
rs968611138 2582 dbSNP
rs1207271380 2587 dbSNP
rs1463879391 2588 dbSNP
rs1268083581 2590 dbSNP
rs1021374512 2591 dbSNP
rs1245429397 2591 dbSNP
rs1204335285 2593 dbSNP
rs1325818651 2595 dbSNP
rs1254455556 2601 dbSNP
rs1232894989 2602 dbSNP
rs1010088663 2605 dbSNP
rs1006522604 2607 dbSNP
rs1245166701 2611 dbSNP
rs1309804462 2614 dbSNP
rs1355266354 2617 dbSNP
rs533396906 2620 dbSNP
rs372117047 2622 dbSNP
rs1048126973 2623 dbSNP
rs1201812370 2626 dbSNP
rs1319864442 2631 dbSNP
rs1461100373 2633 dbSNP
rs997699438 2634 dbSNP
rs931050416 2640 dbSNP
rs868280307 2641 dbSNP
rs567552833 2652 dbSNP
rs1038753725 2653 dbSNP
rs942896308 2659 dbSNP
rs910141437 2660 dbSNP
rs1483950909 2669 dbSNP
rs1301259219 2674 dbSNP
rs1403639013 2678 dbSNP
rs1170429078 2679 dbSNP
rs1465178011 2682 dbSNP
rs375108940 2685 dbSNP
rs1331983451 2687 dbSNP
rs1379088408 2688 dbSNP
rs1389569388 2690 dbSNP
rs1195725594 2699 dbSNP
rs928212488 2701 dbSNP
rs1312246569 2704 dbSNP
rs1234975677 2713 dbSNP
rs930174570 2716 dbSNP
rs1323303981 2717 dbSNP
rs1199721789 2720 dbSNP
rs1448072836 2727 dbSNP
rs1479982896 2728 dbSNP
rs79562236 2729 dbSNP
rs1268166173 2732 dbSNP
rs1184798182 2737 dbSNP
rs1174584288 2738 dbSNP
rs564860874 2744 dbSNP
rs1171169911 2745 dbSNP
rs1276661555 2750 dbSNP
rs1199957038 2751 dbSNP
rs960432976 2752 dbSNP
rs1253334006 2762 dbSNP
rs927261814 2763 dbSNP
rs1339849410 2764 dbSNP
rs989478565 2769 dbSNP
rs1453358268 2774 dbSNP
rs3743779 2775 dbSNP
rs1280787696 2778 dbSNP
rs1031531659 2782 dbSNP
rs1218856962 2785 dbSNP
rs1260459001 2787 dbSNP
rs1331547083 2789 dbSNP
rs1306070619 2791 dbSNP
rs968583082 2792 dbSNP
rs1021510099 2795 dbSNP
rs111862754 2796 dbSNP
rs955879403 2800 dbSNP
rs1489518283 2801 dbSNP
rs1197423020 2808 dbSNP
rs1268229678 2808 dbSNP
rs758560380 2809 dbSNP
rs1478307334 2810 dbSNP
rs1196095451 2813 dbSNP
rs1428189784 2816 dbSNP
rs997269122 2823 dbSNP
rs560562989 2830 dbSNP
rs186599881 2832 dbSNP
rs1169686657 2833 dbSNP
rs574890197 2835 dbSNP
rs561649723 2839 dbSNP
rs1019509085 2844 dbSNP
rs1300821919 2848 dbSNP
rs1446912231 2856 dbSNP
rs1017242645 2857 dbSNP
rs1005911420 2860 dbSNP
rs888674345 2867 dbSNP
rs1048628758 2868 dbSNP
rs889748641 2869 dbSNP
rs151157712 2877 dbSNP
rs531157882 2890 dbSNP
rs1324066965 2893 dbSNP
rs575263705 2895 dbSNP
rs1291203216 2900 dbSNP
rs779591331 2901 dbSNP
rs1252888748 2903 dbSNP
rs1240527815 2910 dbSNP
rs897312168 2911 dbSNP
rs1037205257 2918 dbSNP
rs1414250194 2920 dbSNP
rs1446439290 2920 dbSNP
rs1273572008 2925 dbSNP
rs1005010429 2927 dbSNP
rs796425351 2933 dbSNP
rs1319902084 2934 dbSNP
rs374271769 2938 dbSNP
rs538785177 2946 dbSNP
rs927399548 2947 dbSNP
rs1282375279 2950 dbSNP
rs980044034 2954 dbSNP
rs1243409246 2955 dbSNP
rs1381778349 2955 dbSNP
rs1244437602 2957 dbSNP
rs573293565 2963 dbSNP
rs916853046 2964 dbSNP
rs914597411 2965 dbSNP
rs553142363 2976 dbSNP
rs1407678644 2983 dbSNP
rs936687311 2987 dbSNP
rs988743218 2990 dbSNP
rs1426984797 2992 dbSNP
rs536467507 2993 dbSNP
rs1030130916 3007 dbSNP
rs1237858439 3009 dbSNP
rs1181713342 3011 dbSNP
rs976324344 3012 dbSNP
rs1470550061 3013 dbSNP
rs1405153741 3014 dbSNP
rs1399812570 3027 dbSNP
rs754201477 3039 dbSNP
rs770941232 3047 dbSNP
rs562835314 3048 dbSNP
rs1450857758 3054 dbSNP
rs1006005072 3055 dbSNP
rs1180125066 3055 dbSNP
rs1378346628 3057 dbSNP
rs1444985187 3058 dbSNP
rs1482811599 3063 dbSNP
rs1349978329 3067 dbSNP
rs1269904524 3070 dbSNP
rs887425627 3079 dbSNP
rs1222886414 3084 dbSNP
rs1026432456 3088 dbSNP
rs994394827 3094 dbSNP
rs1287609134 3095 dbSNP
rs142119700 3098 dbSNP
rs746970305 3108 dbSNP
rs1201585076 3110 dbSNP
rs1350753660 3115 dbSNP
rs1289617878 3117 dbSNP
rs1183881888 3120 dbSNP
rs1230692254 3125 dbSNP
rs1469121948 3139 dbSNP
rs1172831011 3142 dbSNP
rs1430909711 3146 dbSNP
rs1057275074 3148 dbSNP
rs1467875881 3153 dbSNP
rs1176244738 3155 dbSNP
rs1401465860 3159 dbSNP
rs985316607 3161 dbSNP
rs764508116 3169 dbSNP
rs1335283164 3174 dbSNP
rs563782091 3180 dbSNP
rs1285250771 3185 dbSNP
rs1343913862 3186 dbSNP
rs550929725 3190 dbSNP
rs371066972 3191 dbSNP
rs537323964 3193 dbSNP
rs571313743 3194 dbSNP
rs961335058 3196 dbSNP
rs1015307359 3200 dbSNP
rs1323461341 3207 dbSNP
rs1199005510 3208 dbSNP
rs989227865 3212 dbSNP
rs1003025427 3213 dbSNP
rs1479285688 3214 dbSNP
rs79918830 3233 dbSNP
rs78515149 3234 dbSNP
rs1424797504 3237 dbSNP
rs923199438 3244 dbSNP
rs759077669 3245 dbSNP
rs1166688588 3246 dbSNP
rs780004994 3262 dbSNP
rs964530020 3265 dbSNP
rs528035147 3267 dbSNP
rs565771881 3279 dbSNP
rs1017474897 3280 dbSNP
rs773818593 3281 dbSNP
rs1430215048 3298 dbSNP
rs148656106 3299 dbSNP
rs1025938049 3300 dbSNP
rs770820237 3301 dbSNP
rs1478885895 3302 dbSNP
rs1244825941 3305 dbSNP
rs1268172912 3307 dbSNP
rs895371893 3311 dbSNP
rs530351420 3312 dbSNP
rs762931467 3325 dbSNP
rs756427217 3333 dbSNP
rs1447444449 3334 dbSNP
rs1489600683 3335 dbSNP
rs1221326765 3336 dbSNP
rs1036339540 3342 dbSNP
rs1269975769 3344 dbSNP
rs1003101988 3352 dbSNP
rs906038318 3362 dbSNP
rs1191540754 3375 dbSNP
rs1372859093 3376 dbSNP
rs1473443225 3376 dbSNP
rs772944241 3377 dbSNP
rs1011583595 3379 dbSNP
rs9941275 3387 dbSNP
rs1220651459 3388 dbSNP
rs79102905 3389 dbSNP
rs1387476017 3393 dbSNP
rs1380742208 3394 dbSNP
rs912683004 3396 dbSNP
rs934673161 3397 dbSNP
rs1274561332 3398 dbSNP
rs1325577199 3401 dbSNP
rs923328259 3403 dbSNP
rs1246629792 3406 dbSNP
rs780450624 3419 dbSNP
rs1317030413 3423 dbSNP
rs1431966161 3424 dbSNP
rs1244673131 3431 dbSNP
rs1040298443 3438 dbSNP
rs1319190466 3444 dbSNP
rs1456744669 3445 dbSNP
rs1486679203 3450 dbSNP
rs1202988037 3454 dbSNP
rs1407016588 3456 dbSNP
rs943308367 3458 dbSNP
rs919800550 3460 dbSNP
rs1412930199 3464 dbSNP
rs910351183 3471 dbSNP
rs961349684 3472 dbSNP
rs984624177 3474 dbSNP
rs1365593712 3477 dbSNP
rs1015672632 3481 dbSNP
rs1475632533 3485 dbSNP
rs1158144092 3486 dbSNP
rs951749641 3488 dbSNP
rs541053328 3503 dbSNP
rs971868109 3506 dbSNP
rs1380549804 3513 dbSNP
rs1464037502 3517 dbSNP
rs1243157446 3524 dbSNP
rs565195052 3526 dbSNP
rs779031580 3527 dbSNP
rs895327494 3530 dbSNP
rs1206021061 3539 dbSNP
rs145014288 3549 dbSNP
rs778074961 3550 dbSNP
rs1417357157 3557 dbSNP
rs1296044121 3567 dbSNP
rs756484837 3570 dbSNP
rs573124864 3571 dbSNP
rs1178411114 3576 dbSNP
rs891194600 3580 dbSNP
rs1469239363 3581 dbSNP
rs1298607493 3584 dbSNP
rs1374916208 3586 dbSNP
rs1389125792 3590 dbSNP
rs1305646884 3596 dbSNP
rs1345794728 3598 dbSNP
rs1384204816 3599 dbSNP
rs1049841671 3602 dbSNP
rs932437484 3603 dbSNP
rs919745155 3608 dbSNP
rs973970155 3609 dbSNP
rs1205870641 3610 dbSNP
rs939913704 3618 dbSNP
rs531197889 3619 dbSNP
rs1011719207 3620 dbSNP
rs1195344392 3622 dbSNP
rs1269695682 3624 dbSNP
rs1171454589 3629 dbSNP
rs981484089 3630 dbSNP
rs1391840782 3633 dbSNP
rs971054515 3635 dbSNP
rs1432340534 3636 dbSNP
rs1022637297 3637 dbSNP
rs542740884 3643 dbSNP
rs1053602398 3644 dbSNP
rs1297167203 3647 dbSNP
rs991191658 3649 dbSNP
rs1183044629 3652 dbSNP
rs1482015036 3653 dbSNP
rs1236500271 3656 dbSNP
rs1345300814 3658 dbSNP
rs998974938 3665 dbSNP
rs1204858162 3668 dbSNP
rs901839757 3669 dbSNP
rs957158501 3671 dbSNP
rs1272863095 3675 dbSNP
rs1032906530 3681 dbSNP
rs1490841115 3688 dbSNP
rs1220570977 3701 dbSNP
rs1268383918 3702 dbSNP
rs1001071093 3709 dbSNP
rs576846549 3710 dbSNP
rs182699466 3711 dbSNP
rs1426720721 3717 dbSNP
rs910487309 3719 dbSNP
rs1385348321 3721 dbSNP
rs557192046 3725 dbSNP
rs1048894974 3726 dbSNP
rs930458824 3727 dbSNP
rs1348986741 3730 dbSNP
rs142229427 3731 dbSNP
rs1431011413 3731 dbSNP
rs919120453 3735 dbSNP
rs1291063410 3737 dbSNP
rs61399205 3738 dbSNP
rs1214499078 3739 dbSNP
rs1316292850 3745 dbSNP
rs898603596 3746 dbSNP
rs1038598576 3750 dbSNP
rs939881996 3751 dbSNP
rs1317818672 3760 dbSNP
rs1298944709 3764 dbSNP
rs960519931 3767 dbSNP
rs1411836438 3768 dbSNP
rs1484748339 3770 dbSNP
rs571575032 3773 dbSNP
rs558037656 3774 dbSNP
rs368575178 3781 dbSNP
rs970260818 3782 dbSNP
rs908305235 3784 dbSNP
rs915575553 3785 dbSNP
rs1412433564 3786 dbSNP
rs1400949649 3789 dbSNP
rs991139276 3801 dbSNP
rs79435406 3807 dbSNP
rs35325345 3811 dbSNP
rs1434758495 3814 dbSNP
rs1337773595 3817 dbSNP
rs1385670988 3819 dbSNP
rs1451089171 3820 dbSNP
rs1166875758 3826 dbSNP
rs1374075556 3828 dbSNP
rs750413608 3832 dbSNP
rs1282364407 3833 dbSNP
rs71382727 3835 dbSNP
rs1207925144 3838 dbSNP
rs957755092 3839 dbSNP
rs1182290754 3840 dbSNP
rs1462645354 3843 dbSNP
rs1181620640 3850 dbSNP
rs925741206 3860 dbSNP
rs1470159955 3861 dbSNP
rs1178594290 3867 dbSNP
rs1473332838 3870 dbSNP
rs190101666 3872 dbSNP
rs879910927 3872 dbSNP
rs549088339 3873 dbSNP
rs1490629889 3874 dbSNP
rs1021589232 3877 dbSNP
rs901927639 3886 dbSNP
rs767196151 3890 dbSNP
rs1267725162 3891 dbSNP
rs1008475393 3894 dbSNP
rs1018932234 3914 dbSNP
rs955644908 3915 dbSNP
rs1028308125 3929 dbSNP
rs1007576054 3930 dbSNP
rs1307707854 3940 dbSNP
rs1224344635 3943 dbSNP
rs1283706753 3946 dbSNP
rs889147671 3948 dbSNP
rs1348804655 3953 dbSNP
rs1277765594 3966 dbSNP
rs759165494 3968 dbSNP
rs930616192 3972 dbSNP
rs1408955943 3976 dbSNP
rs528975293 3979 dbSNP
rs897643937 3980 dbSNP
rs1391266055 3982 dbSNP
rs1036205697 3986 dbSNP
rs1295203361 3991 dbSNP
rs1172336870 3994 dbSNP
rs1224 3998 dbSNP
rs1412128572 3999 dbSNP
rs1327003925 4005 dbSNP
rs1045581407 4010 dbSNP
rs1349233890 4016 dbSNP
rs927737575 4019 dbSNP
rs949953504 4021 dbSNP
rs773868487 4028 dbSNP
rs947712193 4031 dbSNP
rs915858569 4032 dbSNP
rs1230852805 4036 dbSNP
rs550771564 4040 dbSNP
rs762568325 4042 dbSNP
rs1253246570 4043 dbSNP
rs1216240686 4055 dbSNP
rs990806623 4056 dbSNP
rs1482403724 4060 dbSNP
rs1222799453 4064 dbSNP
rs957681167 4065 dbSNP
rs1198684892 4075 dbSNP
rs1489703039 4075 dbSNP
rs1032224767 4076 dbSNP
rs1458383604 4078 dbSNP
rs1409283862 4080 dbSNP
rs765905870 4082 dbSNP
rs530963763 4083 dbSNP
rs925655565 4085 dbSNP
rs565258063 4086 dbSNP
rs545342070 4087 dbSNP
rs977207903 4088 dbSNP
rs1386418281 4089 dbSNP
rs1322715055 4093 dbSNP
rs1326743685 4094 dbSNP
rs186171697 4096 dbSNP
rs559468063 4099 dbSNP
rs762300104 4108 dbSNP
rs1353894104 4109 dbSNP
rs1028592922 4119 dbSNP
rs1327207918 4120 dbSNP
rs144110527 4122 dbSNP
rs139392025 4123 dbSNP
rs897744894 4131 dbSNP
rs1247998839 4132 dbSNP
rs1333063277 4135 dbSNP
rs1165619824 4139 dbSNP
rs1036581212 4140 dbSNP
rs939213272 4148 dbSNP
rs1457604107 4153 dbSNP
rs1159296000 4162 dbSNP
rs1384897005 4164 dbSNP
rs906405716 4171 dbSNP
rs1366765649 4173 dbSNP
rs1044776015 4174 dbSNP
rs1321195427 4175 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Mo7e
Location of target site 3'UTR
Original Description (Extracted from the article) ... "We observed an up to 80% inhibition of N4BP1 (NEDD4 binding protein 1) ...

- Girardot M; Pecquet C; Boukour S; Knoops L; et al., 2010, Blood.

Article - Girardot M; Pecquet C; Boukour S; Knoops L; et al.
- Blood, 2010
BCR-ABL negative myeloproliferative neoplasms (MPNs; polycythemia vera, essential thrombocythemia, primary myelofibrosis) are malignant diseases arising from a multipotent hematopoietic progenitor, frequently altered by JAK2 V617F or other JAK/STAT activating mutations. The thrombopoietin receptor (TpoR, MPL) is one of the major dimeric cytokine receptors that use JAK2 in the myeloid lineage, and was found to be down-modulated in certain MPN patients. We searched for negative regulators of MPL expression. Here we report that miR-28 targets the 3' untranslated (3'UTR) region of MPL, inhibiting its translation, as well as other proteins potentially involved in megakaryocyte differentiation, such as E2F6. Expression of miR-28 in CD34-derived megakaryocytes inhibited terminal differentiation. miR-28 was found to be overexpressed in platelets of a fraction of MPN patients, while it was expressed at constant low levels in platelets from healthy subjects. Constitutive activation of STAT5 leading to autonomous growth of hematopoietic cell lines was associated with increased miR-28 expression. We discuss how down-modulating MPL and other targets of miR-28, and of related miR-708 and miR-151, could contribute to MPN pathogenicity.
LinkOut: [PMID: 20445018]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28260 Renal cortex and medulla 0.838 1.7e-4 0.786 7.2e-4 13 Click to see details
GSE28544 Breast cancer 0.519 4.7e-3 0.528 4.0e-3 24 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis -0.342 7.0e-2 -0.092 3.5e-1 20 Click to see details
GSE26953 Aortic valvular endothelial cells -0.307 7.2e-2 -0.288 8.6e-2 24 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.299 7.3e-2 -0.502 5.3e-3 25 Click to see details
GSE21687 Ependynoma primary tumors -0.152 1.2e-1 -0.184 7.3e-2 64 Click to see details
GSE38226 Liver fibrosis 0.154 2.5e-1 0.252 1.4e-1 21 Click to see details
GSE17498 Multiple myeloma 0.09 2.9e-1 0.027 4.3e-1 40 Click to see details
GSE42095 Differentiated embryonic stem cells -0.069 3.8e-1 0.051 4.1e-1 23 Click to see details
GSE32688 Pancreatic cancer -0.053 3.9e-1 -0.048 4.0e-1 32 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.297 4.0e-1 -0.500 3.3e-1 3 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.297 4.0e-1 -0.500 3.3e-1 3 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.297 4.0e-1 -0.500 3.3e-1 3 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
ESCA 0.849 0 0.827 0 11 Click to see details
STAD 0.352 0.02 0.322 0.04 32 Click to see details
KIRP 0.304 0.05 0.212 0.12 32 Click to see details
THCA 0.219 0.05 0.328 0.01 59 Click to see details
HNSC 0.242 0.06 0.234 0.07 42 Click to see details
LUAD 0.369 0.12 0.350 0.13 12 Click to see details
LIHC -0.171 0.14 -0.229 0.07 42 Click to see details
PCPG 0.826 0.19 0.500 0.33 3 Click to see details
KIRC 0.083 0.25 0.007 0.48 68 Click to see details
COAD 0.603 0.29 0.500 0.33 3 Click to see details
PAAD -0.392 0.3 -0.400 0.3 4 Click to see details
PRAD 0.074 0.3 0.076 0.3 50 Click to see details
LUSC -0.078 0.32 -0.101 0.27 38 Click to see details
CESC -0.509 0.33 -0.500 0.33 3 Click to see details
BLCA 0.085 0.37 0.309 0.11 18 Click to see details
BRCA 0.022 0.42 0.042 0.35 84 Click to see details
UCEC 0.044 0.43 -0.072 0.38 19 Click to see details
KICH -0.025 0.45 -0.055 0.4 25 Click to see details
CHOL 0.02 0.48 0.133 0.37 9 Click to see details
CHOL 0.02 0.48 0.133 0.37 9 Click to see details
CHOL 0.02 0.48 0.133 0.37 9 Click to see details
39 hsa-miR-708-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT006410 MPL MPL proto-oncogene, thrombopoietin receptor 2 1
MIRT006412 N4BP1 NEDD4 binding protein 1 1 1
MIRT006415 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 1 1
MIRT006417 TEX261 testis expressed 261 1 1
MIRT098750 PHACTR2 phosphatase and actin regulator 2 2 4
MIRT106226 C8ORF44-SGK3 C8orf44-SGK3 readthrough 2 2
MIRT106238 SGK3 serum/glucocorticoid regulated kinase family member 3 2 2
MIRT118987 BCL2L11 BCL2 like 11 2 2
MIRT135257 TMBIM6 transmembrane BAX inhibitor motif containing 6 2 8
MIRT175244 PSAT1 phosphoserine aminotransferase 1 2 6
MIRT215590 SUB1 SUB1 homolog, transcriptional regulator 2 2
MIRT273159 RAD51AP1 RAD51 associated protein 1 2 2
MIRT290312 RNF138 ring finger protein 138 2 2
MIRT344689 CRLF3 cytokine receptor like factor 3 2 4
MIRT441854 KCNJ10 potassium voltage-gated channel subfamily J member 10 2 2
MIRT454894 SEPT8 septin 8 2 16
MIRT476647 G2E3 G2/M-phase specific E3 ubiquitin protein ligase 2 2
MIRT483005 RASGRP3 RAS guanyl releasing protein 3 2 2
MIRT503376 SCAMP1 secretory carrier membrane protein 1 2 2
MIRT506802 KLHL15 kelch like family member 15 2 6
MIRT507255 FGF2 fibroblast growth factor 2 2 8
MIRT512206 C1orf21 chromosome 1 open reading frame 21 2 6
MIRT526269 CCDC169 coiled-coil domain containing 169 2 2
MIRT536797 HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 2 2
MIRT537112 GP5 glycoprotein V platelet 2 4
MIRT537991 DPP8 dipeptidyl peptidase 8 2 2
MIRT544395 SMC5 structural maintenance of chromosomes 5 2 2
MIRT547532 MARCH6 membrane associated ring-CH-type finger 6 2 2
MIRT559095 C18orf25 chromosome 18 open reading frame 25 2 2
MIRT568179 CCDC6 coiled-coil domain containing 6 2 2
MIRT568441 ARPP19 cAMP regulated phosphoprotein 19 2 2
MIRT568543 AKT3 AKT serine/threonine kinase 3 2 2
MIRT571568 WDR26 WD repeat domain 26 2 2
MIRT571877 NCL nucleolin 2 2
MIRT575657 Synpo synaptopodin 2 2
MIRT624649 ASXL3 additional sex combs like 3, transcriptional regulator 2 2
MIRT698454 TM4SF1 transmembrane 4 L six family member 1 2 2
MIRT700268 RAP2B RAP2B, member of RAS oncogene family 2 2
MIRT704283 DENND5B DENN domain containing 5B 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-708 Doxorubicin approved 31703 Microarray heart 22859947 2012 up-regulated
miR-708 Phenethyl isothiocyanate(PEITC) NULL 16741 Microarray neonatal mice liver 20145010 2010 down-regulated
miR-708 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miR-708 Ascorbate approved 54670067 Microarray Metastatic melanoma cell lines 25202679 2014 up-regualted
miR-708 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miR-708 Ursodeoxycholic acid (UDCA) approved 31401 Microarray rat Liver 20689055 2010 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-708 Tamoxifen 2733525 NSC180973 approved sensitive Low Breast Cancer cell line (MCF-7, T47D)
hsa-mir-708 Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-mir-708 Paclitaxel 36314 NSC125973 approved resistant cell line (W1)
hsa-mir-708 Cisplatin 5460033 NSC119875 approved resistant cell line (W1)
hsa-mir-708 Methotrexate 126941 NSC740 approved sensitive cell line (W1)
hsa-mir-708 Topotecan 60699 NSC609699 approved resistant cell line (W1)
hsa-mir-708 Vincristine 5978 approved sensitive cell line (W1)
hsa-mir-708 Tamoxifen 2733525 NSC180973 approved sensitive cell line (MCF7)
hsa-mir-708 Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)
hsa-miR-708-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-708-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-miR-708-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-708-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-708-3p Tamoxifen 2733525 NSC180973 approved sensitive cell line (TamR4)
hsa-miR-708-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-708-3p Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)
hsa-miR-708-3p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)

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