miRTarBase - #MIRT007110


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pre-miRNA Information
pre-miRNA mmu-mir-183   
Genomic Coordinates chr6: 30169668 - 30169737
Synonyms Mirn183, mmu-mir-183, Mir183
Description Mus musculus miR-183 stem-loop
Comment The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies .
RNA Secondary Structure

Mature miRNA Information
Mature miRNA mmu-miR-183-5p
Sequence 6| UAUGGCACUGGUAGAAUUCACU |27
Evidence Experimental
Experiments Cloned
Putative Targets

Biomarker Information
Biomarker ID Name Type Discovered From Mode Level Source Testing Methods
B9GR6X miR-183 Safety Biomarker (SAF) Clinical/Experimental Data Expression Increase Plasma Quantitative reverse transcription PCR
B1I4RW miR-183-5p Safety Biomarker (SAF) Clinical/Experimental Data Expression Increase Urine Real-time polymerase chain reaction
Gene Information
Gene Symbol Taok1   
Synonyms 2810468K05Rik, AU020252, D130018F14Rik, Map3k16, Markk, Psk2, mKIAA1361
Description TAO kinase 1
Transcript NM_144825   
Expression
Putative miRNA Targets on Taok1
3'UTR of Taok1
(miRNA target sites are highlighted)		 
>Taok1|NM_144825|3'UTR
   1 TAATTGAAAGTGGCAATTCCTCTGGAGCTGTCTGCCAAAAGAAACTGCCTACAGACATCATCACAGCAGCCTCCTCACTT
  81 GGGTACTACCGTGTGGAAGCTGTGCATATGGTATATTTTATTTGTCTTTGTAAAGCGTTATGTTTTGTGTTTACTAATTG
 161 GGATGTCATAGTATTTGGCTGCCGGGGTTTTTGTGGTTGGCTTTTTGTTTTTGTTTAACTTTTGGAAAATTTTTAAAGTG
 241 ATAATAGATAAGTATTTCATGTATGTGGCAAAAAAAAAAAATTGGCTTAATTAGAAGGGGTATTATCTGAACAATATAAA
 321 AACAGAATGAAGCAAGCTAATCTGAATCATCACTTTAGGGTATCCATAGCCTAAGAAATGTGTCAGAAGATCTAAAGCCT
 401 TCCTTCATATTCCAGTTCTGTGAGTCCCTAACAGCAGGCAGCATCCATGCTGAAGCACATACACCTCCGCTCCTCACCAG
 481 TGGGTTTTCTTTATTTATGAATTGATCTGATTTCTCAACCTCATTTGAACTAAAAAACAAGACCATGAACATTAAAAGAT
 561 TGCATTTACCTTTTCAGTGGTAGAAAATCATTTAGTTCTTTGCTATAAATGATTCAGAATTTTGTCAGATTTTGTAGGTT
 641 GTATCATCGTAAGACGGAGTTGCATAAGGAGATCATAAGCTGTGTGGCTATTGCACTAACAAGCCTGTGAGCTTTCAGAG
 721 GGGAAAAACTAGAGGGCGAGAGGGGCCCCTGAAAGTTCCTGTGACAGGGATGCTCAGCAGGGAGGAGGGAAAGCCTGTAT
 801 AGCTAGCCTGACATTTTGTTTCTTGTACAATATCTCATGTGACCCAAACTTGAGACTCCAAACAGTACCTTTGCTTTGTT
 881 TGTACAAAAATGAAGACCTATAGCCAACACAAAGCAAATGCCAGAGGTATTGGATGATGCCATATTTGAACTGCCATCTA
 961 TTAGCATATTCATCACACTACATAGACATAGTTTTACTGCCCCCTTTTTAGCTCATGGGATTTCCTGTTTACAGGTAGCA
1041 ATAGTCAATTATTTAACTACTTAGTTGCCACCAGGAGTCACTGAGCCAATGACTATCAGCTGCTGACTAATCTTCACACT
1121 GTAGTTATTGCTTCATTTACAGGTCCTCTGTGCTTAATTGCTGTTTTTGTTGCTGTAGTACCTTATGAATTCTTAATTCA
1201 TTGAGACTTAGTGACCATCTGGGTCCATGTTAATATCATATAATAGCAAATTCCTTTCAGAAGTCTCTAGCTTTAGTGCT
1281 AAAATACTACTGAGAAAGGAACTAGGTAGTTTGGTGAATGAAAGAAAACAAAATTTGAAGATATTATGTAGTGGTCAAGG
1361 ACCACTAATATTTGGGGAGTGTGTTTTGTCTGTTCTTCAATGAAGGATCAATCCAGTGTTCTTCATCAATGTTAGTTAAT
1441 ATCCCATTGCTTGTGTGGCGCCTTGAGTTGGTGGTAGACTAGGGCAAATGCCCTCTTTAGTGAGAGACCAGAGGTTTTGT
1521 ATAAGTTATTGTCCTGCTCCCTTTTCAGTTGTCTTGAAGAGCTCTTGCTACTAACTTTGGGTCCTGCTTTTCATTTAGGT
1601 AGATGGTAAGCATTCTCTTAATCATAATTAGAACAAACTAGTGACCAAATTGTCATCTGCTAGTATGGAAGTTCTTAGTT
1681 TTCTTAACCATGCTTTATGTCTTGTCCAGGTATGTCAGTCCAGTTTCCATGACGTACCCCCTTCAGAAGTTTCTGACATT
1761 GGTTTGAGGTTTTCTGACACTAATTAAAAGAAAAATTAGATCAGGGTGTGGTAGCAAATGCCTATAATCCCAGCATTTAG
1841 GAGGCAGGGATAGGAATCTCAGGTTCAAGGCTGCCTACAAGTGTCTCAAAAAAGAAAGAACAAAAGAAAGGTAGATGCTA
1921 TAGTATAGGTCCTTTGAAAATCCAATAGAAGGTTAATAGTATTCACACACAGGTCTAGGCAGGGTTTTAAACATATTCCC
2001 CATCAGTTTTTAGGTTAACATATACTTGCTATAGCTAATGAAAAGGGCTTTTCTTTTTTCTTTTTCTTTCTCTTTTTTTC
2081 CTTTTTCACTCAAAATACTATTAAGGAGTTTCTCAGACAAATTGAAAATTCTATATGTTTTGAGGAAATAAGGGGAAGCT
2161 TTAGAGTTTAATAGGATATTCAAAACTATAAAAGAATATCATCTTAAAAAACTGTTCTGGCAACTATCTGCTACCAGAAG
2241 GTTAGATTGAGAAAGCAGATCCAATATATGCAAGACATTTCTTCAAACTCCAAACTACTACCAGAAACACATTTTATCAC
2321 CCATTGTGAGAGTCACTTGGTCAAATTTAGTTAATGAGTCCATTTTGATCATAATGCACTCACACTAGTGTGTTTGAATA
2401 CTGACTGTCTGTCTGTCCAGTAAGGATTTCTGCCCCCATCTAATTGTGTGGCACCCAGTTTTTCCATGTAGGTCATTATA
2481 CCTGGATGATAACATCAATTTAGTTACAATGCATGTAGTTTGCACAATGATTAAAATGAATAGGTTTGTGTTTATAGCCT
2561 ATAATAACTCTAGTTGAATCATGTACACAGCAGGAGTGGTCACAGTAAAAACTGGTAGCAGGAAAATTTGAAAGGGTTTG
2641 AAATGCCCTGAAATCAGGGCAAGTACTTAATGGGGAAAAAAAAGCAGAAATGTCAACATTTGACCAAATTAACACTACCT
2721 CCTCCCCAGTTGTTGGTATTCATTCATTATATGTGTGTTTAACAGGATGAGAGCATGGCGAGCTTGTAGCACACCAGAGG
2801 TTGTAGACCTATATCTGGTATCCAGAACCTGACAGGGAAACAGTTCTTGGTCCCCCTTTTTTGGGGTCAGCATTTTAAAA
2881 ATGCAAAGCCTATATGTTGAGACATTGTATTCCTAATTAGATTCTCTGTCCTTTGCACATAACTTTCTTTTAAACTTAGT
2961 TCTAACCCTAAATCTTGACATCAGAAAGTGTTTGCACTGTATAAACAATGTTAGCTGAAAGCATGTTTATTTTTTAAGGA
3041 GCTCCTGCTCTTCTGCACATTTCCATATCTAGAGATGGATAGTCCTGAACTTGACGTCACACCCACAGGTGAAACAGCCC
3121 GAAGTCAAGGCCTTGCTAGTAAATGGAGCTTTGTACATAGTCATTGTGATGTCTTGGCTGCCCGGACACCACGTAAACAT
3201 AACACTAAAGAAACTGTCCTGGAGATCCCATCCTGCTACTAAGAAGTTTTCTGTACATCACTTCCAAACATTGGAAACTT
3281 TCAGATCATAAGGCAGAATTTAGTAATTTTGTGCTTCTGTTAATGTCTAGCATTTTAAACATAGGATAACATTGTTTTGG
3361 ACACTGGAATAATATGATTTATTTTCACCTGTAAAAATGACTTCATTGTACTTGAACACCTTTGCATTTCTCCATTTGTG
3441 CCATTTACAAGTGGAAATAAATTTTATTATACCATGATCTACTGGCGTTTTAAAACTGTTAAATGTGCACATTTTGGGTA
3521 TAGCTATTTTCACTTGTATGTATATATTGTATATACATATAAGTGTCTGTATGTGTGTATAGATGGATTGGTATAACTCA
3601 TTCTAAACGTGTCTGCCAGGGCTCAAGTTTTATTGTTCTTGCCCCACTCCCACCCCATGTTACAGCAAGACTGGTCTTAC
3681 AGAGTGAGTACTCTGGGTGATGCTTACGGGAAGGAGATTGGTAGATGCAGTCTTTTTTTCCCCCTTAGCACTTGTATGAG
3761 TGAGGAGAAAGTTAGGTAAAGATTGAAACTATAAATTACAGTGCAGTAAACTGTGCTAGGGAAGGAATCAGTTACTATTT
3841 AAGTTTGTTTTACAATGCAATAAAAGATACAAGCTGCAGAGAAAAGTAAACTCTGCAAAGAACACTGGTAATAATTGTTC
3921 TGCAAAGGTTAAGAAAGCCACTGAGTCACAGTCTTCATGGACTTTTGGGGTTTCTTAGTGTTGGATTTTTGGGGTTTCTC
4001 ATTTACTTTTTACTCTTAATACTAATGCTTATGTGTTTCACTGAGTATCAAAACTGCCAAGAAGGGTAACTAAGGTTCCT
4081 AAACTGTAAGATGAGCAGGAGATGATCACTGGGAGAGAAAGCATACTGGATTGAAGGAAGGGCTGTCTCCTTTTAACTTC
4161 TTGTTGATAGTTGCAAGTTCTTTATGCACCTTCTACCCCTTCTGAGCCACTACTATTCAAGCAGAGATTTTGTCTAATAG
4241 AACATGCCTTTCTTGCTTTTGCTTCTTTTCTTTTGAGACATGTACCCTTTCTGATTGGATAATTGATGTTTAGCCAAGGC
4321 TGGCCTCAAAATACTAGTAATCTTTCTGTAAGCCTCTCAAGTACTGGGATTACAGGCATGAACCACCATGCCTATAGCCA
4401 CAGCAACCCATTCTTTTGGAGGTTTTATAGTTCTCCATTTGTCTCATGTTCCGAATGTGAAGTGTCCTAATGTGTATTAA
4481 AGTCAGAAAATAATATATTTAAGGTATACTAAGTATGAATCTGCTATGATAAAAGAAATTCTCACTTCTCAAATAGTCTT
4561 CTTGTAAGGAGCATTGGGCTGTCATCTTTGAGCTGCTTATCAAAATACAGATCATTATTGCATATATGCAAATTCTGTTT
4641 TATTTTATCCCTAATAACAGAAGTCTCCCTTCCATGGTTTTAGCGTTGCCTTTTTAAAAAGGCACTCACCCTGAGTTGTT
4721 AAGAACTGGACCTGCCCCACCCTCAGATTCCTTAAAGGATGAAGAGTGTGCTGTACACTCAGCATATGTGCCTCTTGTAT
4801 GCAAGGACTACTGATTGAAGTCTGTTTTGCTGTGTCTGGTTATGTTGTCTGCACTTTTATGAAATCACTACAATAGATCT
4881 ACGTTGGAAATAACTATCAATTTGTAAAGAAATTTTTATTAAACACTGTAGAAAAAGTGAAGCTGAGAACTCTTTTGTGC
4961 ATTTATATTTCCTACTGAATTCTGGTAGCCCACTTTTAACATTGTATTGACTTTTTTTTTTTTTTTTTGATTATATTCAG
5041 ATTTCCAAACAAGTGCTGGCCTTCAGATCATAAGTATAAGAAATATGCATCATATCTGCCTATTGCAGGCTTCTGAAACT
5121 TGCACTGCCCATCCATGCAAAAATAAGTATCTTAAATAAAAGCAGAGAGCAAAAACTGGGGAGCCATGTACTATGTCACC
5201 ACATCTGTTAACTGTTTCCTGCAATCTAAACTGAAGTGTGTGTGTGGGTGTGTGTATGTGTATTGGGGGTTTTGTTTTGC
5281 TTTGCTTTTAAATATACAAGGGGTTCTTCTTTAAATAGAGGAAAAGGTTAATCCTCTCCAGCAGGATGCCCACTGGATAT
5361 ATTAACATCTGTAGGTAGTTGGAAGTGTAGAGAGAAGAGAAGGTAAGACTTCTCAGTGAATGGAAGGATGTCTTGATGCT
5441 CAAGAGTCCCCGCCCCCAAAGTACGGGTAATTCAGCCTGCACAGTTTCCTTTCACTCATAGTTTCACAATTACGAGTGAA
5521 AAATCATGTAATTATCTGTAAATATGTAGCTAACAAATTGACCTAGTTTCTGTACTTTTTTGGTTTTGTACTAAAGTTTA
5601 TAGGTCTGTGCCAGCTAGAGAGGAGTTGCTGTCATTGCTAGTCGTGCTCTAGCATACAACCCTGAAACCATCCTAGGTGA
5681 CATTTTAGAATTAATACTTAAGTGTTGTTAAATGGGGACATGGAGCTTAATCATTGGTCAGGTTTGAAGTCTTTTGAAGC
5761 TAAGTAATTTTATTTAATATGATTACATGTCGTCAGTCATGAGTGAGGTGTAGGGAGTCTCCCTCCCCAAGTGGCCATGT
5841 TTACAGAGTGTTGTCTACAAAGTGCAAGTGTGTTAATGTTTATGTAAATTATGCAGGTGATAACTTTATGGTTTGGGACT
5921 GTTTATGGGCTCTTTTAAGTGAATTTTCAAATGAAATGAACTATGCTTATTGCTGGCACATTGATCCCATTTCTGGAACA
6001 TTTCCTACTTCCAGAATTCCGTATGTTCCTTAGACATTACCCCCACTTAACCTCCCTTCCTCTGATATGCCTTGTAGCTA
6081 AGATTTAAAAGACTGTTGAACATAGATGAGGGGTATGCATTTCTTAAAAATCCATGAACCCTCAATTGTATGCTTTCAGT
6161 ATTGTGTTATATGTTTCTATGGCAACTTTGAAGTCAGTGGTTTAGAAATGAGATACCAATGTTAATGAAAAGTATGTACT
6241 CTTTGCTTTTGCATGGCTTGGCTTAGTATCCAAGGTATATTAGAGCCACTTGAAAGCATGAAGACCAGTTATATGGAAAC
6321 AGGTTTCTCTCAGTGGCACATTTTGCTTTTTCTTAGCCCTCAAATACATTGCCTCGGCATGAACATTATTGTTAATATAA
6401 ATTGCACATGGTCATCGAGTGAATTATAAAATTTTGAAAAGATGCAGCTGCCCAATATTAACAGTTTTAGTTGGTCTCTA
6481 TCTCAAATAACAGTGTAGGTATTGGAACCCTTGTAGCCCTTTTGGGGGTCAAACAGGTATATGGATTTATCAAGGAGGGC
6561 ATTGGCTGCCCCTGGGGTATTGCCACGCTGTTGTCTTGCTGCCCATTCACTCCATGTGCTGCTGTCCTTCCTTCACTTCA
6641 TACTCTCAAAGAAACCATCACCCTTTCTTCCTATTTTTTTTTGTCTTTTATTCCACATTAAATGGGAATTGTGCCTATTT
6721 AGATTGCCCCTCCAGTTAAATACACATGTAATCCAAGCCAGAGATAAGATGGAAGAACATTTTTTTTTCAAGTTCACTTG
6801 GCCAGTAACTTATCTAACAAACTGTTTTACCACACTATCTTGACACTTGATAGAAGAGCCTATTAGGAGTCACAGTGGTT
6881 TCGTAGAGTAAAACCCAAGTGAGGAGGGATGTGTGGGGTTTCCATTAGGAAATAATTTCGTTCTTGGTTTACTCTTTAAG
6961 ATCCTTCTCTGCTAGTTTAGAATAGGTTAATTTTTTTTTAATTTTTTTAGGGAAATTTTTACAAAAATAATGGTCTGATG
7041 TAAATACCATTTTAAAGTACAGTGCACATAACTCCCTAGGCTGTTCCAACCTGACTATTTGTAAATGCTTTAGAGTTTTA
7121 AATTAACACTTCTGTTGCTAAATACTATTTATGTAAGTCTGAAAAGGTTTTTAACCCATATAAAACATTTAAATAATGCA
7201 GGTTATTATGAGCAAGTTAGCTTTGAGAACCCTCCTTTTAGTATATGAAAAAGCCTAATGCGCATTCATGAGGTTGGAGA
7281 GACTATGAGAAATATGTATAGTGTATATTTTAAACAGCTTTGCTTGTATTGTGAAGATTTAAGAACAAACTTGAGATTTT
7361 TAAAGTTAACTATTAACACAGTTTTAACATAAGTTATCCCACTGGGTTTAAAAGCATCTTGAATGTATAACCCTTCTGTA
7441 ACCCAGGCTGGTCTTTGCTTTTACTGAACATCCAAACGTTATTTATATTTTAATTTTATGTACTCATTTCTTTTTGTTTT
7521 CCTCAAACAGCATGTTGTTGTTGGGGTGTTTTGTTTTGTTTTTGTTTGTTTTGGGTTTTTTTTTTTTTTTGCACATGTAG
7601 AAATTTTTTAAAAGAAGGAAATTAAGACATGATTTTTCTCTAGATTTTCTTCACTTCAGTCTTTCTACTAACCTCGTAAA
7681 AACCATGGCTTCCATTTGCTTTATTTGTGCAAATGCCAGGGTTGGTTTTTATTTTTATTTTTGCTATTTACCTAAAAAGA
7761 AAAAGAGACAATGCTTCAGTCAACTGCTTTTTTATTTAAAATTTAAAGAAAAAAAAAAGAAAAAAAAAGCTGTAACCTTA
7841 TCATTTCTGAGTAGACCATTAAGAGAAATGCACACCTGTCAGCCCAGGACCAGCTTTGGTGGCTAAAGGGAATATTTTAA
7921 CTCGCAAGGTGATGTTCTGTACAAAACGTGGTATATGTTACCCACAGTCCATTTCAGTTATTCCCACAAGTCAGGTCCAG
8001 ATAAATGAGGGTTATCAGCTAACTGATATGTTATCATTGAGGTTCGTCAATGAATTTGTACATTTCTAGTTCCCTTTGGT
8081 GAAGGGAAAAATGATTTTGCAAGACCTAGATTTTGGCTTGGTTTCTTGCCTCCTTTTTTGGCAGCCTTCATCTTTTCCTA
8161 AAGCCCTTGAGCCTGTAGGGTTTTCATAGTGGACAAAGGACTTAAATGGTCTTTTAAAACTGGGATAGTTTTTGGGGAAA
8241 GGGCAAAAGATTATCATATTGAACATGTAGTATCCCAATACTCTCAACAGTGGATAATTATGAGTAAACCCGGTCCTTTC
8321 GATGTTTAGAGTAAGCAGAGGCCCACAGTGGAGGCTTACCAAAGGTTGCAATGAGGAAGAGGCCTCTCCCTCACTGTCAG
8401 CACCAGCTGGTAAAGGTGACTGTGCAGATGTGCATTTTCCTTTTGGTAGAAATGGTCCACAGCACTAACTGGTAAGGCTT
8481 ATTGTACAGTATATTGTCAGTATTCTTCTGGTTCAGCATACCTTATAGTTCGTATATAACCTGTATTAATTGTATAGATT
8561 GTGCATTTAAAGCTGTTACCAAGTTGTCAGAACCCTAAGAATGAAAACAGGTCATATGTAATATTTTGTTTGTAAGTATC
8641 CTTTGTATCATAGCAAAGGAAATGTTTAAAAGATCAACTGTAATAAAAGTAATTTTAGTACACAGAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ucACUUAAGAUGGU---CACGGUAu 5'
            || |||:  |||   ||||||| 
Target 5' ttTGCATTTCTCCATTTGTGCCATt 3'
 3421 - 3445 160.00 -13.50
2 
miRNA  3' ucACUUAAGAU----GGUCACGGUau 5'
            | || |:||    :| ||||||  
Target 5' acTAAAGTTTATAGGTCTGTGCCAgc 3'
 5590 - 5615 134.00 -10.80
3 
miRNA  3' ucacuUAAGAU----GGUCACG-GUAu 5'
               |||:||     |||||| ||| 
Target 5' ataccATTTTAAAGTACAGTGCACATa 3'
 7044 - 7070 127.00 -13.10
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions Cochlear Sensory Epithelia
Disease 216965.0
Tools used in this research DAVID , TargetScan
Original Description (Extracted from the article) ... "Verification of the predicted targets revealed a significant upregulation of Taok1 ...

- Patel M; Cai Q; Ding D; Salvi R; Hu Z; Hu BH, 2013, PloS one.

Article - Patel M; Cai Q; Ding D; Salvi R; Hu Z; Hu BH
- PloS one, 2013
Acoustic trauma, one of the leading causes of sensorineural hearing loss, induces sensory hair cell damage in the cochlea. Identifying the molecular mechanisms involved in regulating sensory hair cell death is critical towards developing effective treatments for preventing hair cell damage. Recently, microRNAs (miRNAs) have been shown to participate in the regulatory mechanisms of inner ear development and homeostasis. However, their involvement in cochlear sensory cell degeneration following acoustic trauma is unknown. Here, we profiled the expression pattern of miRNAs in the cochlear sensory epithelium, defined miRNA responses to acoustic overstimulation, and explored potential mRNA targets of miRNAs that may be responsible for the stress responses of the cochlea. Expression analysis of miRNAs in the cochlear sensory epithelium revealed constitutive expression of 176 miRNAs, many of which have not been previously reported in cochlear tissue. Exposure to intense noise caused significant threshold shift and apoptotic activity in the cochleae. Gene expression analysis of noise-traumatized cochleae revealed time-dependent transcriptional changes in the expression of miRNAs. Target prediction analysis revealed potential target genes of the significantly downregulated miRNAs, many of which had cell death- and apoptosis-related functions. Verification of the predicted targets revealed a significant upregulation of Taok1, a target of miRNA-183. Moreover, inhibition of miR-183 with morpholino antisense oligos in cochlear organotypic cultures revealed a negative correlation between the expression levels of miR-183 and Taok1, suggesting the presence of a miR-183/Taok1 target pair. Together, miRNA profiling as well as the target analysis and validation suggest the involvement of miRNAs in the regulation of the degenerative process of the cochlea following acoustic overstimulation. The miR-183/Taok1 target pair is likely to play a role in this regulatory process.
LinkOut: [PMID: 23472202]
13 mmu-miR-183-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT007110 Taok1 TAO kinase 1 1 1
MIRT052910 Zeb2 zinc finger E-box binding homeobox 2 1 1
MIRT054441 Lrp6 low density lipoprotein receptor-related protein 6 3 1
MIRT578108 Nudcd3 NudC domain containing 3 1 2
MIRT578204 Naaa N-acylethanolamine acid amidase 1 1
MIRT580025 Whsc1 nuclear receptor binding SET domain protein 2 1 1
MIRT581640 Prex2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 1 2
MIRT583410 Fzd1 frizzled class receptor 1 1 1
MIRT585851 Slc35a1 solute carrier family 35 (CMP-sialic acid transporter), member 1 1 1
MIRT600846 Gatsl2 GATS protein-like 2 1 1
MIRT605738 Gm10778 predicted gene 10778 1 1
MIRT605995 Kalrn kalirin, RhoGEF kinase 1 1
MIRT735197 Foxo1 forkhead box O1 2 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-183 (S)-3,5-dihydroxyphenylglycine (DHPG) NULL 443586 Quantitative real-time PCR mouse brain 22309833 2012 up-regulated
miR-183 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 down-regulated
miR-183 Hydroxamic acid HDACi LAQ824 NULL NULL Microarray breast cancer cell line SKBr3 16452179 2006 down-regulated
miR-183 5-aza-2'-deoxycytidine (5-Aza-CdR) + 4-phenylbutyric acid (PBA) NULL NULL Microarray T24 human bladder cancer cells 16766263 2006 up-regulated
miR-183 Vorinostat (SAHA) approved 5311 Microarray A549 human non-small cell lung cancer cells 19513533 2009 up-regulated
miR-183 Mistletoe lectin-I NULL NULL Microarray colorectal cancer cells CLY cells 20955366 2011 down-regulated
miR-183 Mistletoe lectin-I NULL NULL Microarray colorectal cancer cells HT-29 cells 20955366 2011 down-regulated
miR-183 Arsenic trioxide approved 14888 Quantitative real-time PCR acute promyelocytic leukemia 22072212 2012 up-regulated
miR-183 Ethanol NULL 702 Quantitative real-time PCR CIE10 22141737 2012 down-regulated
miR-183 Piceatannol NULL 667639 Quantitative real-time PCR leukemia U937 cells 22705645 2012 down-regulated
miR-183 Comfrey NULL 6440495 Microarray rat liver 21370286 2011 up-regulated
miR-183 ACTH approved 16132265 Quantitative real-time PCR adrenals and granulosa cells 24205079 2014 up-regulated
miR-183 Dexamethasone approved 5743 Quantitative real-time PCR adrenals and granulosa cells 24205079 2014 up-regulated
miR-183 Aristolochic acid NULL 2236 Microarray kidney 25106556 2014 up-regualted
miR-183 Perfluorooctane sulfonate NULL 74483 Microarray zebrafish embryos 20878907 2011 up-regulated
miR-183 Ethanol NULL 702 Quantitative real-time PCR zebrafish embryos 22298809 2012 up-regulated

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