miRTarBase - #MIRT016671


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pre-miRNA Information
pre-miRNA hsa-mir-425   
Genomic Coordinates chr3: 49020148 - 49020234
Synonyms MIRN425, hsa-mir-425, MIR425
Description Homo sapiens miR-425 stem-loop
Comment The mature sequences were previously named miR-425-5p and miR-425-3p in .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-425-5p
Sequence 14| AAUGACACGAUCACUCCCGUUGA |36
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 7 3 - 49020215 27298257 MiREDiBase
A-to-I 10 3 - 49020212 26028588, 27298257 MiREDiBase
C-to-U 8 3 - 49020214 25692236, 27298257, 28550310 MiREDiBase
C-to-U 12 3 - 49020210 25692236, 27298257, 28550310 MiREDiBase
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN31612894 6 COSMIC
COSN30467646 18 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1023872187 3 dbSNP
rs991519440 6 dbSNP
rs1258514883 9 dbSNP
rs778093756 14 dbSNP
rs1481930136 18 dbSNP
rs960897691 19 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TAOK1   
Synonyms KFC-B, MAP3K16, MARKK, PSK-2, PSK2, TAO1, hKFC-B, hTAOK1
Description TAO kinase 1
Transcript NM_020791   
Expression
Putative miRNA Targets on TAOK1
3'UTR of TAOK1
(miRNA target sites are highlighted)		 
>TAOK1|NM_020791|3'UTR
   1 CTTAATAATTGAGAGTGGCAATTCCGCTGGAGCTGTCTGCCAAAAGAAACTGCCTACAGACATCATCACAGCAGCCTCCT
  81 CACTTGGGTACTACAGTGTGGAAGCTGAGTGCATATGGTATATTTTATTCATTTTTGTAAAGCGTTCTGTTTTGTGTTTA
 161 CTAATTGGGATGTCATAGTACTTGGCTGCCGGGTTTGTTTGTTTTTGGGGAAATTTTGAAAAGTGGAGTTGATATTAAAA
 241 ATAAATGTGTATGTGTGTACATATATATACACACACATACACATATATTATGCATGTGGTGAAAAGAATTGGCTAGATAG
 321 GGGATTTTTCTGAACACTGCAAAAATAGAACGTAGCAAAATGGCTTCAGTTATCACTTTTGGGTGTCTGTATCCTAAGAA
 401 GTTTCTGAAAAGATCTAAAGCCTTTTTATCCCATATCCCAAATTCTTATGAGCCACTCACAGCAGGCAGCATATGTTGAA
 481 ATAAGTTATTACTGGTACACACCTGCATTGCCTCACCAGTGTATTTATTTGTTATTAAATTGATCTGACTTCTCAGCCTC
 561 ATTTGGACTAAAAAAAGAAAGCAGAAATCCATGAACACATTGCTTCTCGGCCTTTTGGCTAAGATCAAGTGTAGAAATCC
 641 ATGAACACTAAAGGACTTCATTGATTTTTTCAGAGAGTAGAAAACAACTTAGTTTTTCTTTTTTCCTGAATGCGTCATAG
 721 GCTTGTGAGTGATTTTTGTCCATTCAATTGTGCCTTCTTTGTATTATGATAAGATGGGGGTACTTAAGGAGATCACAAGT
 801 TGTGTGAGGATTGCATTAACAAACCTATGAGCCTTCAATGGGGAAGACCAGAAGGGTGAGAGGGGCCCTGAAAGTTCATA
 881 TGGTGGGTATGTCCCGCAGCAGAGTGAGGAGATGAAGCTTACGTGTCCTGACGTTTTGTTGCTTATACTGTGATATCTCA
 961 TCCTAGCTAAGCTCTATAATGCCCAAGACCCCAAACAGTACTTTTACTTTGTTTGTACAAAAACAAAGACATATAGCCAA
1041 TACAAATCAAATGCCGGAGGTGTTTGATGCCATATTTGCAAATTGCCATCTATTGAAATTCTCGTCACACTACATAGACA
1121 TAATTGTTATCTCCTTTTGGCTTATGTGATTTTCTGTTTACAAGTAGAATAGCCAATTATTTAAATGTTTAGTTGCCACA
1201 GTGAACCAGGAGTCACTGAGCCAATGACTTTACCAGCTGCTGACTAATCTTCATCACCACTGTAGATTTTGCTGCATGTG
1281 CAGGTCCTCTATTTTTAATTGCTGTTTTCGTTGCTGCAGTACTTTACAAACTTCTAGTTCGTTGAGACTTAGTGACCATT
1361 TGGCATCAAGTTAACATCACACAATAGGAAACACCACTTCCACAAGTCTCAAGCCTCAGTGCTAAAGTACTACTGAAAAG
1441 GAACTAGGAAGTTTGGCCAATTAAAAAAAAAAAGTAAAATAAGTTATAGTGGTCAGGGAATCTCTTGACGAAAGCTAACT
1521 CTTATTTTTCAGGGGGCACATGTTTTGTTTTGTTATGTTTTGTTGTACAATGAAGGATGAACCCAATGCTAAAAAGTCAG
1601 TTATTTTCTTGGTTTTCCATTTCTTGTATATAAATTGTGTTGGAGGTGGGTAGGAAGCTGTGAGTATGACTTGAAGAAAA
1681 ATATCCTTTTCAGTGACAAATCAGAGTTTCTTACAAGTTATTGTCCTGCTCCCTTCCAAGTTGTCTTGAAGAATCCTTGC
1761 TGCTAACTCTGGATCCTGCTTTTCCTATAGTCAGAGGGCTCCAAGGTAGAACTCTCTAAGTCCCTCTCAATGGCACTCTT
1841 TGCCTAGACCAAACTAATGACCAAACAGTAATCAATCTATCACTGTTGAAGTCCTGGTTTTCTCAACCAAATTTTAAGTC
1921 TTTCCCAGGTATGTCAGTCGAGTTGCCATGAATCCTCACCTGTAGGAGTTTCTGGGATTCATTTTAAGGAAACTGGAAGA
2001 AAATTAATGTTTTAATGTAAATGTTTTTAAAACCAAGATCACCATAGAGTTCACACAAAATTTTAGGCAGTGTTTCAAGA
2081 AGCACTCTTATGTGTTGTTCTTTCAGCCCATGCTCCAGGTCACCGGTTTTTAGGTAAACATGACATGACATGTACTTGTA
2161 ATATCAGTGAAAGGGGCTTTTAGTCGTCTCAGTATCTTTTTTGCATTCAGGTATTATAGCGTTTCCAACAAATTGAGAAA
2241 TTACTTATTTGGTGTAAAATGACGAGAGAGCTTTAGAATTTAATAAAATGTCAAAAATACAATTTGATACCCTTAAAAAT
2321 TATTCATAGATCTGGCTGCTCTGTACTACTGGATGGGTGGAATAGGGAAGCAGATCACTTTTGCATACAAAAACTCTTTC
2401 AAACCCAAAATATTATTGGTGGTACATTTTAAAGTCCAATTGTGGACTTAAATTAGTCAAATTGAGAGTTACTGAGTCCA
2481 TTCAGATCTCCAGTAGGGTTTTGTATCTAATGTATTTGGCCACCAGTTTTACATGTAGGTCATGACTATACCTGGATTTT
2561 ATCATTAAGTTAACTTTAAAGTATATACAGTTTGCAAAAAATGATTCAAATTAATTGGTTTGTATATGTTTGTGAGATCT
2641 AGCTTCTGAGGAATCTCATACATAGTAGGAACCATCATAGAGTAAAGCTTGTAGCAGAAAAATTGGAAGGGTTTTGAGAT
2721 ATCCTAGAGAAAGAGCAAGCACTTTCTGAATCAGTGGGGAAATATCAATATTTGATCAAATTAACACTACCTCCTTCCCA
2801 GTGTTGGTGTTCACTCACTATATGTCTTTAAGAAAATTAAAACTATGGAAAATTTGTCTAGCATATCAGAAGTTGTAAAT
2881 GCTATATCTGGTATCCAGAGGCTGGCTGTAAAAAGTTCCTTGGGGTCACTCTATCTCACATTTTTTTTGGTTAGCATTTT
2961 AAAAATGCAAAGCCACATACTTTGAAATATATTATTCCAAATTGAGCTCCCTTCCCTTTGCACATATTTTTTCCTCCCCT
3041 TATTGAAGTCAGCTCTAACCCCAAATTCTAGTATCCAAAAGTATTTTTATTTGTATAATGCTATCTGAAAAATGTGTTTA
3121 TATTATATTTTCAGAGCTGCAATTCTTATTCGCCATTTCAATACCTAGAGATAGAGAGTCTTGTATTTGAAGCCACACAC
3201 ACTGGTGTAATATGCTTAGTACTCTAGGTCAAGGATTTGTTGGTAAATGGAACATTTTAGCATAGTCATGATTTTTGGTT
3281 GCCTAGACATCAGGTAAACATTCAGTACACTAAAGAAACTATCCTGGACACTCCCTCCTGCTTCCACCAATTTTTTTCTC
3361 ACCCCCTTTTCAAAAATTGAAAACTCTATGAGTGTCTTTTTGAGACCATAAAGCAGACTTTAGTAACTTTCTATTTCTGT
3441 AAGTACTAAATGTCTGGCATTTTAAACTTTTGTAGAATACATTATGTTGGACACTGGAATAATACTATTTATTTTCACCT
3521 GTGAAAAATGACTTCATTGTACTTGAAACACCTCCTTTGCATTTCTCCATTTGTGCCATTCACTAGTGGAAATAAATTGT
3601 ATTATACCATGATCTACTGGCTTTTTAAAACTGTATTAAATATGCACATTTTTGGTATAGCTATTATCATTTGTATGTAT
3681 ATATTGTATATACATATGAGTGTCTGTATGTGTGTATAGATGGATGGATGTAACTCATACTGTACATTTCCATCAGGGCA
3761 CTTAAAAGTTCTGTTATTTTTGTTTGGTTTTGTTATTTCAGTCCTCAGTTAAGGCAAGAATGCATGTGTTTCTTAAGAAT
3841 GAGTACTCTGCGTTGATGTTTATGAGAAGGTGGTCATTAGATGCAGTCTTTTCCTTTTTAATCCCCTCTTAGCACTTCTG
3921 TGAGTGGAGAGGACATTAAGTAAAATTTGGAATCATAAGTTGCAATGCAGTAAAATGGTGCTGGGGAAGGAGCCAGTTAG
4001 TGTTTCTGTGAGTTTGTGTTGTGATGCAATAAGAGATAAGTAATGCAGAGAGAAATGAACCATGGAAAGTAAGAACACTG
4081 ATGGTGATTCCTCTGCAAAGATGATAAGAAAAAGAACCAATAAATCACACAATCTTTATGTGCTTTCTATATGTATTTCT
4161 TAGTAGTGATACCATTGATCCTCTTACTTTTTTTACTCCATTAATACTAATAATTATATACTTTGCTGAGGATCAAAACA
4241 GCCAAGAAAGGAATTACTGCTAAAGCATCTAAGATTCTCCTGAACTGTAAAATCAACAGGAAATGGCCACTGGGAGAGAA
4321 GGATTTGGTATTGGGTGAGGGGCTTTCTCCCTTTACCTGCCTCTTCTTGCTTGCTAATAGTAAGTTCTTTGTGCACCTTC
4401 CACCACTTCTGAGCCACTACTATTCAAGTAGAGATTTGCCCCAACACATTAACTTTTTCCTTGGAGATTTATATGGTCCT
4481 GCATTTTGTCCTGTGCTCACAATGTGAAGTGTCTTCTGTATTCAAATCAAAAAATAATATATTTAAGGTATATAAGTGTG
4561 AATCTCCTATAATGATGGAAGAAGAGGTTCTCTTGTCTTAGATAGAAAAGAGCCTTCTCCAAGAGCAATGTCAAAACTTG
4641 GGCTGTCATCTTTGAGCTGTTTACCAAAATACAGACCATTATTGAAGAAAAACAAATTATCTATTTTGTTTTCCCCCATC
4721 TAACATGATAGTGCCCCCAACCAGGTTGTAGCATTGCCTTTTAAAAGAGACTCACTCACTCTTAGTTTTTAAGAACTGGA
4801 AATTTCCCATCCTCAGATCCCTTAAAGGATGAAGAGTTGGCTGTACACTTAGCGGACTTGCCTCTTGTATGCAAGGACTA
4881 CTGATTGAAGTCTGTTTTGCTGTGTCTGGTTATGTTGTCTGCACTTTTATGAAATCACTACAATAGGTCTGCATTGGAAA
4961 TGACTATTAATTTGTAAAGAAGTAAGTTTTATTAAACACTGTCTAGAAAAAGAAAGTGAAGCTGAGAACTCTTCCTTTAT
5041 TGTGCATTTATATTTTCTGCTGAATTCCGGTAGTTCCCTTTAAAGTCATGTTGACTAATGTTTTCCTCCTTGTTTGTATT
5121 CAGATTTCCAAAATTTCACTCATACAAGGGAAGAGACTCCATTTAGCTTAACGGTAGTCTTTAGATCATAAGAAATATAT
5201 AAATTAGTATGCACCTTATCTGCCTGTTGTGGGTTTCTTAAACTTGCACTTCCTACCCACCCAAAGATAGATATCCTTTA
5281 AAGAAAATAAAGGCAGAGAATTAAAACTGGGGAGCCATTTACTATGTCACCATCACTGTTAACTGTTTCCCAGCAATCTA
5361 AACTTTTTGAAGTTTCAGAGGTGTATTTTTTTTTTGTATATATGTCTGTGTGATTGTATTGTTTTGTTTCTAAATATACA
5441 AGGAATTCTTTAAATAGAGAAAAAGGTTAATCCTCACTGAAACACCAGGATGCCCACTGGATATACTAATCTGAACATCT
5521 GTAGGTAGTTTGTCATGAAAAAGTGGAGAGAAGATGAGACTTTTGAATGAATGAAAAAGGGTATCTTGATACCCAGAATT
5601 CCCCCCAAAGTACGGGTAATTCAACCTGCACAGTTTTCTTTCACTCAAAGTGTTCAGCACTTGTGAGTGAAAAATCATGT
5681 AATTATCTGTAAATATGTAGCTAACAAATTGACCTAGTTTCTGTATTTTTTTGTTTTTGTACTAAAGTTTATAGGTCTGT
5761 GCCAGCTAGAGAGAAGTTGCTGTCATTACCAGTTGTGGTCCTAGCATCTAACCCTGAAACCATCCTAGGTGACATTTTTA
5841 GAATTAATACTTAAATGTTAAACAGGGGGAAATGAAGCTTAATCATGGTCAGGTTTGAGATCTTTTGCAGTGAAATAATT
5921 TTATTTAATATAAATGATCACATGTCCTCAATCATGAATGAGGTAGGGAGCCTCTCTCCCCCAGTGGCCATGTTTACAAA
6001 AGTGTGTTTTGTCTATAAAGTGCAAGTGTTTTAATGTTTATGTAAATTATGCAGGTGATAACATGGTTTGGAACTGTTTA
6081 TTGGGCTCTTTAACTGAATTTTCAAATGAAATGAACTATGCTTATTGCTGGCACATTGATCCCATTTCTGGAACATTTTT
6161 CCTATTTCCAGAGTTACATATGTTCTTTTGTCATTACCCAATTTAACCTCCCTTTCTCTGATATGCCTTGTAGCCAAAGT
6241 ATTAAAGGCTGATGAACATAGACAAGGGAAATGCATTTCTTAGAAATCCGTGAACCCTCAGTTGTATGCTTTCAGTACTC
6321 GTGTTAATATGTTTCTATGGCAACTCTGAGGTCAGTGGTTTAGAAATGAGATACCAGTGTTAATGAAAAGTGTGTGCTCT
6401 TTGCTTTTGCATGGCTTGGCTTAGTATCCAAGGTATATTAGGGCCACTTGAAAGCATGAAGACCAGTTATATAGGGAACA
6481 GGTTTCTCTCAGTGGCACATTTTGCTTTTTCTGAGCCCCAAATACATTGCCTGGGCATGAACATTGTTACCGTAAATTGC
6561 ACATGGTCATGGACTGAATTATGTGACTTTAAAGGATGTAACTGCCCAACATTTGCAGATTCTGGGTGGTCTATGTGACC
6641 ATTTGTCTCGTATCCAAAAACCCCGGGGCTATTGGAACCCTTCCAACACTTTTTCCTTTGTCATAGACAAGTTTATATAT
6721 AACTTACCAAGATGTTGGCTGTCCTGGTGTATTGCCAGACAGCTCTCTTTTGGTTCCCATTCCAAATGTGCTGCTGTCCT
6801 TCTTTGCATTTCACAATATCAAAGAAACCACCACCCTTCTTCCTAACAGCATTTTATGCCTTTTATTCCACATTAAATGG
6881 GAATTGTGCCTACTTAGGAGTGCCCCTCCAATTAATTACATGTGTCCAAGAATAATCCAAGCTAGAGACACAAGGTGGGA
6961 AAACATTTCAAAAAAAAAAAGTCCTCTTAAGGCCAGTAATTTATCTGAAAAGGTATTTTATCACACCTTGACACCTTATA
7041 TATGAGCCTATTAGGAGCTGCAGGTGGTTTCATAGGGTAAAATCCAAGAAAAGAGAAGGATGTGTGGGGTTTCTATTAGA
7121 AGATAATTTTGTTCTCATTTTACCTTTTCTTTTATGATCCTTCTCTGCTAGAACAGGTTAATTCTCCAAATTTGTTTTGT
7201 TTTGTTTTGTTATTTTTTAGGGAACTCTTTTGCAAAAGCAATGGTCGGATGTAAATAACATTTAAAGTATAGTGCACATA
7281 ACTTCCCCGGACTGTTCCAATCTGATAATTTGTAAATGCTTTAGAGTTTTTTTAATTAACACTTGTGTTGCTAAATTCTA
7361 TTTATGTAAGTCTGCTAAAGTTTTTTAGCCCACTTAAAACTTAAGACAACCATTTAAAATAATGGATGGGTTACTATGAG
7441 CAATTTCGCTTTCAGAACCCCCTTGTTTTAGTATATGAAAAAGCCTAATGCGCATTAATGAGGTTGAAGAGACTATGAGA
7521 AATATGTATAGTGTATATTTTAAAACAGCTTTGCTTGTATTGTGAAGATTTAAAAACAAACTTGAGATTTTTAACGTAAC
7601 TATTAACACAGTTTTAACATAAGTTATCCCACTGGGTTTAAGAGCATCTTGAATGTATAATCCTTTTTGTAACCCAGGTT
7681 GGTTTCTACTTTTACCAGTCACCCAAACATATTTATGTTTTTAGTTTTATGTACTCATTTCCCTTTGTTTTCCTCAAACA
7761 GCATGATTTTTTTGCACATGTAGAAATTTTTTAAAAGAAAGAAATTAGTACATCATTTTCTCTGGATTTTCTTCACTTCC
7841 CTCTTCCTTTCTACTAACTCCTTCCTTAAAGGCCATATCACTCCATTTGCATTATTTGTGCAAATGCCAGGGTTGGTTTT
7921 TATTTTTATTTTTGCTATTTACCTAAAAAAAGAAAATGCTTCAGTCAATTGCTTTTTTATTTAAAAAAAAAAAGAAAAAA
8001 AGCTGTAACCTTATCATTTCTGAGTAGACCATTGAGCGATGAATGCACACCTGTAGTAGCCCAGGACCAGCTGTGGTGGC
8081 TAAAGGGAATATGTTAATTAAGCAAGAGGTTCTTTTCTAAAAGTGGTATCTGTTATCCACAATGTATTTTAGTTATTCCC
8161 ACAAGTCAGGGGTCCAGATAAAATGAGGGTTATCAGCTAACTGATATGCTATCATTGAGGTTCATCAATGAATTTGTACA
8241 TTTCTAGTTCCCTTTGGTGAAGGGAAAAATGATGATTTTGCAAGACCTAGATTTTGGCTTGGTTTCTTGCCTCCTTTTTT
8321 GGCAGCCTTCATCTTCTCATCTCCCAAACCCCCTGAGCCCGTAGGGTTTTCATAGTGGACAAAGAACTTGTGGTCTTTTA
8401 AAACTGGGACTGATACTTTTTTGAGAGAGTATCGTGTCGAAAGTGTGATGTTCTACCACTTTACCAATAACTAATTTTAA
8481 ATACACATTGTCCTCTCGATTTTTGGACCAAACAGACGCTCACAGTGGAGGCTTATCAAGGGTTGCATTGGGGAAGAAGC
8561 CTCTCCCTCTCTGTCAGCACCAGCTGGTAAAGGTGACTGTACAGATGTGCATTTTCCTTTTGGTATAAATGGTCCACAGC
8641 ACTAACTGGTAAGGCTTATTGTACAGTATATTGTCAGTATTCTTCTGGTTCAGCATACCTTATAGTTCATATATAACCTG
8721 TATTAATTGTATAGATTGTGCATTAAAAGCTGTTACCAAGTTGTCAGAACATAAGAGCGAAAACAAGGTCATATGTAATA
8801 TTTTGTTTGTAAGTATCCTTTGTATCATAGCAAAGGAAATGTTTAAAAAAATCAACTGTAATAAAGTAATTTTAGTACAC
8881 AAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aguugCCCUCACUAGCACAGUaa 5'
               | |||| ||||||||:  
Target 5' tttgaGAGAGT-ATCGTGTCGaa 3'
 8420 - 8441 133.00 -17.00
2 
miRNA  3' agUUGCCCUCACU--AGC-ACAGUAa 5'
            |:|  ||| ||  |:| |||||| 
Target 5' ccAGCTAGAGAGAAGTTGCTGTCATt 3'
 5762 - 5787 131.00 -13.80
3 
miRNA  3' agUUGC-CCUC-ACU----A-GCACAGUAa 5'
            |::| |||| |||    | |||||| | 
Target 5' agAGTGAGGAGATGAAGCTTACGTGTCCTg 3'
 901 - 930 127.00 -15.82
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN28104893 11 COSMIC
COSN30114165 47 COSMIC
COSN30133044 72 COSMIC
COSN30544289 144 COSMIC
COSN8241426 271 COSMIC
COSN31562185 319 COSMIC
COSN31549798 341 COSMIC
COSN31480797 368 COSMIC
COSN31611063 376 COSMIC
COSN28830630 933 COSMIC
COSN25471547 1104 COSMIC
COSN31555469 1105 COSMIC
COSN31593984 1105 COSMIC
COSN8602844 1108 COSMIC
COSN6548052 1192 COSMIC
COSN8602845 1227 COSMIC
COSN31549799 1340 COSMIC
COSN31520869 1368 COSMIC
COSN15657408 1472 COSMIC
COSN15657380 1473 COSMIC
COSN15657325 1474 COSMIC
COSN28994098 1474 COSMIC
COSN24151383 1793 COSMIC
COSN24152402 1905 COSMIC
COSN24150280 1940 COSMIC
COSN21122094 1998 COSMIC
COSN26235666 2218 COSMIC
COSN25387246 2618 COSMIC
COSN26531219 3814 COSMIC
COSN24973498 3920 COSMIC
COSN1716147 3929 COSMIC
COSN22894978 4195 COSMIC
COSN21299548 4281 COSMIC
COSN7163298 4349 COSMIC
COSN16066565 4725 COSMIC
COSN24149762 4778 COSMIC
COSN1195113 4983 COSMIC
COSN6101381 5359 COSMIC
COSN27200642 5396 COSMIC
COSN5415243 5690 COSMIC
COSN1716148 5803 COSMIC
COSN21470657 5950 COSMIC
COSN27250538 6124 COSMIC
COSN21085315 6369 COSMIC
COSN33025 6647 COSMIC
COSN29190842 6697 COSMIC
COSN20699846 6745 COSMIC
COSN16068674 6835 COSMIC
COSN28419458 6852 COSMIC
COSN6101382 6864 COSMIC
COSN27501632 6981 COSMIC
COSN28979241 6981 COSMIC
COSN31582839 7771 COSMIC
COSN31528406 7779 COSMIC
COSN26643828 7835 COSMIC
COSN5415245 7886 COSMIC
COSN7163299 7912 COSMIC
COSN16232484 7936 COSMIC
COSN27114475 8004 COSMIC
COSN16162867 8083 COSMIC
COSN20331266 8213 COSMIC
COSN4768753 8266 COSMIC
COSN24701695 8489 COSMIC
COSN31561643 8518 COSMIC
COSN5415246 8548 COSMIC
COSN31550681 8667 COSMIC
COSN26586728 8735 COSMIC
COSN26573089 8768 COSMIC
COSN31597453 8852 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs771986402 2 dbSNP
rs780822346 2 dbSNP
rs1024696137 3 dbSNP
rs1217153139 4 dbSNP
rs535568453 8 dbSNP
rs1331065082 9 dbSNP
rs553541204 13 dbSNP
rs1307510982 17 dbSNP
rs1445073555 22 dbSNP
rs139171312 26 dbSNP
rs1441723178 27 dbSNP
rs780081881 31 dbSNP
rs1238667236 36 dbSNP
rs1479397826 38 dbSNP
rs995367505 40 dbSNP
rs779684261 47 dbSNP
rs377624136 48 dbSNP
rs1176490589 50 dbSNP
rs980492477 57 dbSNP
rs1459198577 61 dbSNP
rs1027049703 70 dbSNP
rs1199798358 73 dbSNP
rs1181798959 74 dbSNP
rs1278251612 80 dbSNP
rs1218944369 87 dbSNP
rs1354639395 96 dbSNP
rs1308835367 99 dbSNP
rs952699434 100 dbSNP
rs951149015 106 dbSNP
rs1445491406 110 dbSNP
rs1313972711 113 dbSNP
rs983097755 114 dbSNP
rs1395944123 116 dbSNP
rs908427110 123 dbSNP
rs986538697 126 dbSNP
rs943857874 140 dbSNP
rs866054805 144 dbSNP
rs1165177225 145 dbSNP
rs1415700272 148 dbSNP
rs1459179999 150 dbSNP
rs1407945128 176 dbSNP
rs772532856 182 dbSNP
rs923365041 191 dbSNP
rs1195878807 192 dbSNP
rs975080287 193 dbSNP
rs1285499313 194 dbSNP
rs1203612801 202 dbSNP
rs914840070 203 dbSNP
rs1334150612 207 dbSNP
rs1354058267 223 dbSNP
rs1381354592 223 dbSNP
rs932039111 224 dbSNP
rs1400008460 225 dbSNP
rs746725443 232 dbSNP
rs1050487208 235 dbSNP
rs775782408 236 dbSNP
rs1295868342 246 dbSNP
rs1406715847 248 dbSNP
rs761483788 250 dbSNP
rs1391049053 252 dbSNP
rs569040318 252 dbSNP
rs1285534918 269 dbSNP
rs752830421 269 dbSNP
rs936649445 271 dbSNP
rs1337925046 275 dbSNP
rs539104272 277 dbSNP
rs1214346321 279 dbSNP
rs1171309177 283 dbSNP
rs1477493996 284 dbSNP
rs977601054 288 dbSNP
rs1052639268 298 dbSNP
rs1453513247 299 dbSNP
rs1259317168 304 dbSNP
rs892695103 310 dbSNP
rs938818974 325 dbSNP
rs1013719977 328 dbSNP
rs1025084673 331 dbSNP
rs894536692 339 dbSNP
rs557733327 340 dbSNP
rs1002359526 341 dbSNP
rs1438023962 349 dbSNP
rs538065602 352 dbSNP
rs1322493470 353 dbSNP
rs1438361496 369 dbSNP
rs1402195814 374 dbSNP
rs554827285 374 dbSNP
rs898429797 387 dbSNP
rs187989356 392 dbSNP
rs772721367 396 dbSNP
rs1003845173 397 dbSNP
rs1240558871 416 dbSNP
rs1015540512 421 dbSNP
rs1198417962 432 dbSNP
rs762509946 434 dbSNP
rs1240386048 443 dbSNP
rs765804272 446 dbSNP
rs1199703993 449 dbSNP
rs1185680885 450 dbSNP
rs751556020 464 dbSNP
rs1271537045 468 dbSNP
rs1220399493 472 dbSNP
rs1424304123 475 dbSNP
rs1273805894 480 dbSNP
rs1231609805 487 dbSNP
rs1378719585 498 dbSNP
rs1331754588 502 dbSNP
rs1008023704 506 dbSNP
rs1352632274 507 dbSNP
rs921093808 519 dbSNP
rs1019798310 522 dbSNP
rs1415038246 524 dbSNP
rs1402983936 525 dbSNP
rs1172112225 532 dbSNP
rs1174100754 564 dbSNP
rs149537132 570 dbSNP
rs953521667 570 dbSNP
rs543276951 571 dbSNP
rs759369805 573 dbSNP
rs1439488613 604 dbSNP
rs1212860789 609 dbSNP
rs936684265 609 dbSNP
rs1443560743 610 dbSNP
rs1021290512 634 dbSNP
rs1335854939 636 dbSNP
rs1324289864 637 dbSNP
rs1208155934 639 dbSNP
rs1052357190 642 dbSNP
rs1355359317 660 dbSNP
rs914183667 664 dbSNP
rs1370903601 665 dbSNP
rs753405469 665 dbSNP
rs949621431 666 dbSNP
rs767370912 671 dbSNP
rs1339842781 694 dbSNP
rs113458784 700 dbSNP
rs76598043 714 dbSNP
rs1002342635 729 dbSNP
rs1048622631 731 dbSNP
rs1282466270 739 dbSNP
rs80278783 739 dbSNP
rs1400418653 740 dbSNP
rs776202355 743 dbSNP
rs1003897065 748 dbSNP
rs1217575032 750 dbSNP
rs1015257458 751 dbSNP
rs1473394651 754 dbSNP
rs1263639487 756 dbSNP
rs1478649414 757 dbSNP
rs567098557 758 dbSNP
rs992982513 776 dbSNP
rs998092440 777 dbSNP
rs1197263589 780 dbSNP
rs1428513064 781 dbSNP
rs1291717453 784 dbSNP
rs1213940735 785 dbSNP
rs868667486 786 dbSNP
rs1378285201 790 dbSNP
rs1291377031 792 dbSNP
rs1412943935 795 dbSNP
rs1342449863 796 dbSNP
rs1298948182 805 dbSNP
rs916009829 812 dbSNP
rs1478092673 821 dbSNP
rs1430255364 824 dbSNP
rs1028208445 826 dbSNP
rs1343696163 833 dbSNP
rs1167298664 836 dbSNP
rs1173800178 838 dbSNP
rs954013596 839 dbSNP
rs978594286 850 dbSNP
rs143107440 855 dbSNP
rs1399783343 857 dbSNP
rs1163395320 871 dbSNP
rs1479121553 880 dbSNP
rs958134936 884 dbSNP
rs1038146551 888 dbSNP
rs533883859 890 dbSNP
rs78836924 892 dbSNP
rs1248115015 894 dbSNP
rs138152422 896 dbSNP
rs1046639768 897 dbSNP
rs1283281780 903 dbSNP
rs1332145624 909 dbSNP
rs182966257 919 dbSNP
rs1271113254 923 dbSNP
rs1277874457 924 dbSNP
rs754105756 926 dbSNP
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rs550470246 934 dbSNP
rs888223664 938 dbSNP
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rs149550134 947 dbSNP
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rs1021760985 957 dbSNP
rs968359724 960 dbSNP
rs1426229748 965 dbSNP
rs1426748844 973 dbSNP
rs998454126 980 dbSNP
rs1467802003 984 dbSNP
rs17766675 986 dbSNP
rs1452134401 989 dbSNP
rs1200864069 993 dbSNP
rs576821852 999 dbSNP
rs1028676064 1001 dbSNP
rs889680856 1006 dbSNP
rs545476061 1008 dbSNP
rs1158934506 1018 dbSNP
rs1381775633 1019 dbSNP
rs200361074 1025 dbSNP
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rs565686111 1032 dbSNP
rs1000466247 1035 dbSNP
rs539498650 1037 dbSNP
rs557482787 1042 dbSNP
rs1302897737 1046 dbSNP
rs1449489421 1057 dbSNP
rs920637424 1063 dbSNP
rs1032826839 1065 dbSNP
rs958403184 1073 dbSNP
rs1391842957 1078 dbSNP
rs1360378656 1079 dbSNP
rs1176223054 1086 dbSNP
rs1044996 1087 dbSNP
rs908485850 1093 dbSNP
rs1392914652 1104 dbSNP
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rs575603133 1115 dbSNP
rs1193989680 1121 dbSNP
rs1335312982 1131 dbSNP
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rs773820139 1145 dbSNP
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rs1347359903 1157 dbSNP
rs187490359 1161 dbSNP
rs899674860 1187 dbSNP
rs1378103292 1188 dbSNP
rs1020962155 1189 dbSNP
rs1306813591 1214 dbSNP
rs970705615 1227 dbSNP
rs1390149449 1235 dbSNP
rs1245461289 1239 dbSNP
rs555200669 1241 dbSNP
rs997045305 1245 dbSNP
rs1433585461 1246 dbSNP
rs573587123 1267 dbSNP
rs1420005484 1269 dbSNP
rs1362985593 1279 dbSNP
rs778832962 1284 dbSNP
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rs982056578 1292 dbSNP
rs11545088 1295 dbSNP
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rs1485386464 1298 dbSNP
rs938267115 1304 dbSNP
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rs984721175 1312 dbSNP
rs746408031 1316 dbSNP
rs1351737602 1335 dbSNP
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rs910041193 1341 dbSNP
rs758791078 1342 dbSNP
rs1323978653 1349 dbSNP
rs184778846 1351 dbSNP
rs960319643 1364 dbSNP
rs1178677953 1390 dbSNP
rs1413560217 1392 dbSNP
rs1353020568 1393 dbSNP
rs1299551120 1402 dbSNP
rs940134161 1403 dbSNP
rs1400194200 1411 dbSNP
rs1239668351 1420 dbSNP
rs1036783662 1435 dbSNP
rs1014499304 1439 dbSNP
rs572483186 1454 dbSNP
rs933657698 1457 dbSNP
rs1023603567 1459 dbSNP
rs1195990341 1463 dbSNP
rs1255465948 1463 dbSNP
rs970251695 1463 dbSNP
rs189204707 1464 dbSNP
rs1369426310 1474 dbSNP
rs1203699502 1476 dbSNP
rs920688099 1477 dbSNP
rs192369727 1487 dbSNP
rs747315645 1488 dbSNP
rs1000113999 1510 dbSNP
rs1033293229 1511 dbSNP
rs891638500 1514 dbSNP
rs911891137 1515 dbSNP
rs944671787 1515 dbSNP
rs1227544600 1523 dbSNP
rs1325430081 1525 dbSNP
rs563232792 1530 dbSNP
rs1447674948 1532 dbSNP
rs867114900 1538 dbSNP
rs1325033546 1541 dbSNP
rs1459782840 1542 dbSNP
rs1021014522 1551 dbSNP
rs1161605165 1551 dbSNP
rs1172845789 1552 dbSNP
rs768995912 1571 dbSNP
rs1380626666 1577 dbSNP
rs1452199345 1596 dbSNP
rs1313634860 1606 dbSNP
rs772916518 1609 dbSNP
rs1191302033 1612 dbSNP
rs1435193384 1626 dbSNP
rs748863766 1627 dbSNP
rs959922178 1638 dbSNP
rs541008847 1640 dbSNP
rs984394105 1647 dbSNP
rs796667969 1651 dbSNP
rs1195803641 1660 dbSNP
rs1199136805 1665 dbSNP
rs1052751934 1668 dbSNP
rs910084272 1674 dbSNP
rs564349154 1677 dbSNP
rs972866008 1680 dbSNP
rs1234930703 1703 dbSNP
rs1459534616 1714 dbSNP
rs531693085 1715 dbSNP
rs773688782 1722 dbSNP
rs1023234126 1724 dbSNP
rs139374009 1726 dbSNP
rs1409377806 1729 dbSNP
rs1395851354 1731 dbSNP
rs933710115 1736 dbSNP
rs544137489 1742 dbSNP
rs1166279906 1747 dbSNP
rs1479104897 1748 dbSNP
rs906078176 1754 dbSNP
rs562408736 1757 dbSNP
rs995042438 1758 dbSNP
rs1027824118 1774 dbSNP
rs950813911 1784 dbSNP
rs79364688 1788 dbSNP
rs1270237831 1789 dbSNP
rs1201708980 1805 dbSNP
rs1466632138 1807 dbSNP
rs144113586 1813 dbSNP
rs1348094988 1814 dbSNP
rs935632406 1815 dbSNP
rs1404016433 1818 dbSNP
rs966090944 1822 dbSNP
rs1469342736 1823 dbSNP
rs566229617 1825 dbSNP
rs1303709871 1826 dbSNP
rs1054382106 1829 dbSNP
rs891690932 1831 dbSNP
rs1010039221 1832 dbSNP
rs1436671512 1837 dbSNP
rs1376215119 1838 dbSNP
rs1045530454 1839 dbSNP
rs1173245281 1839 dbSNP
rs184270664 1851 dbSNP
rs1003630734 1853 dbSNP
rs1382532309 1862 dbSNP
rs551409337 1865 dbSNP
rs569319714 1870 dbSNP
rs145992224 1876 dbSNP
rs1219172104 1884 dbSNP
rs959401161 1909 dbSNP
rs1188953845 1927 dbSNP
rs1256280097 1932 dbSNP
rs1320884766 1934 dbSNP
rs370634234 1940 dbSNP
rs561953636 1941 dbSNP
rs567248913 1942 dbSNP
rs1484042733 1946 dbSNP
rs1285884423 1971 dbSNP
rs1415391234 1989 dbSNP
rs527830373 1995 dbSNP
rs961606874 2003 dbSNP
rs373757886 2005 dbSNP
rs1347213000 2010 dbSNP
rs922763172 2024 dbSNP
rs139889568 2034 dbSNP
rs376870648 2038 dbSNP
rs985235217 2043 dbSNP
rs1052805248 2044 dbSNP
rs547529362 2045 dbSNP
rs76062881 2046 dbSNP
rs189166882 2050 dbSNP
rs1416500702 2051 dbSNP
rs1185214043 2059 dbSNP
rs1489037162 2064 dbSNP
rs1242349226 2065 dbSNP
rs1360914161 2068 dbSNP
rs1445058224 2070 dbSNP
rs1451931894 2072 dbSNP
rs36099080 2083 dbSNP
rs1334117023 2088 dbSNP
rs1359675546 2091 dbSNP
rs913181369 2092 dbSNP
rs995082251 2105 dbSNP
rs602056 2108 dbSNP
rs115413537 2125 dbSNP
rs760609884 2126 dbSNP
rs1462400289 2127 dbSNP
rs1218525494 2138 dbSNP
rs549883205 2139 dbSNP
rs1429776753 2150 dbSNP
rs1005032233 2151 dbSNP
rs1185553987 2162 dbSNP
rs1474250058 2163 dbSNP
rs907050876 2165 dbSNP
rs1001733215 2170 dbSNP
rs1019043199 2177 dbSNP
rs181528676 2186 dbSNP
rs763945690 2187 dbSNP
rs1055232986 2195 dbSNP
rs1029405210 2200 dbSNP
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rs543884069 2202 dbSNP
rs978655644 2206 dbSNP
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rs562041827 2212 dbSNP
rs1016925920 2216 dbSNP
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rs142108370 2219 dbSNP
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rs1267439744 2222 dbSNP
rs988573634 2222 dbSNP
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rs1407816185 2261 dbSNP
rs386385870 2262 dbSNP
rs200275614 2264 dbSNP
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rs67346866 2265 dbSNP
rs75254343 2265 dbSNP
rs1336307719 2271 dbSNP
rs1233477286 2276 dbSNP
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rs1480949048 2293 dbSNP
rs867440096 2301 dbSNP
rs1282742337 2303 dbSNP
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rs1235380306 2304 dbSNP
rs1370695473 2308 dbSNP
rs1417333446 2313 dbSNP
rs570003760 2322 dbSNP
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rs930258142 2376 dbSNP
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rs1176621728 2397 dbSNP
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rs534203711 2519 dbSNP
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rs534636125 2602 dbSNP
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rs1297266007 2633 dbSNP
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rs1286938762 2638 dbSNP
rs994130430 2640 dbSNP
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rs1032902831 2645 dbSNP
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rs114883092 2663 dbSNP
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rs1207262027 2698 dbSNP
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rs1378973744 2771 dbSNP
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rs1325132253 2800 dbSNP
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rs1027481243 2808 dbSNP
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rs1187009176 2849 dbSNP
rs540487247 2859 dbSNP
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rs989853894 2891 dbSNP
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rs897221507 3024 dbSNP
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rs1016608704 3758 dbSNP
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rs987300307 3852 dbSNP
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rs1254460562 3862 dbSNP
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rs1392039059 3994 dbSNP
rs907154126 4006 dbSNP
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rs750410265 4054 dbSNP
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rs903364648 4070 dbSNP
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rs1228775319 4089 dbSNP
rs1341160858 4100 dbSNP
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rs1252101376 4161 dbSNP
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rs963323022 4179 dbSNP
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rs1370217579 4216 dbSNP
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rs528170201 4218 dbSNP
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rs988258371 4280 dbSNP
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rs1333949405 4326 dbSNP
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rs1276208099 4391 dbSNP
rs937971230 4392 dbSNP
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rs1236629553 4399 dbSNP
rs1316832863 4404 dbSNP
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rs887664517 4410 dbSNP
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rs1328542042 4439 dbSNP
rs765318262 4442 dbSNP
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rs1230194584 4450 dbSNP
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rs1257321889 4499 dbSNP
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rs894244237 4557 dbSNP
rs1463508907 4566 dbSNP
rs953092909 4570 dbSNP
rs1223872509 4571 dbSNP
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rs1289414927 4577 dbSNP
rs1226886408 4584 dbSNP
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rs1032587613 4591 dbSNP
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rs72353361 4599 dbSNP
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rs567772991 4602 dbSNP
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rs575950625 4647 dbSNP
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rs780848891 4695 dbSNP
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rs909152298 4704 dbSNP
rs369283573 4710 dbSNP
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rs638730 4725 dbSNP
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rs1197400284 4754 dbSNP
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rs924889397 4761 dbSNP
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rs1051537084 4764 dbSNP
rs1258191587 4770 dbSNP
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rs58207204 4775 dbSNP
rs377286027 4778 dbSNP
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rs1367999516 8498 dbSNP
rs1294674158 8499 dbSNP
rs919806022 8502 dbSNP
rs949549436 8509 dbSNP
rs1046158934 8510 dbSNP
rs1422576405 8514 dbSNP
rs1477943379 8514 dbSNP
rs148425817 8518 dbSNP
rs1355549809 8519 dbSNP
rs1481332470 8535 dbSNP
rs937684005 8536 dbSNP
rs1267936386 8549 dbSNP
rs1209219320 8557 dbSNP
rs1444778162 8560 dbSNP
rs1047317666 8564 dbSNP
rs1263790357 8565 dbSNP
rs1048076396 8567 dbSNP
rs1311648382 8571 dbSNP
rs1318854380 8592 dbSNP
rs1277877176 8593 dbSNP
rs1217147101 8599 dbSNP
rs1333237507 8600 dbSNP
rs764602200 8605 dbSNP
rs575788385 8615 dbSNP
rs1387863147 8619 dbSNP
rs1299401767 8624 dbSNP
rs762333594 8631 dbSNP
rs1465745388 8648 dbSNP
rs1399093544 8659 dbSNP
rs943781321 8660 dbSNP
rs1004129677 8662 dbSNP
rs1378013579 8668 dbSNP
rs1337515668 8679 dbSNP
rs1037315021 8683 dbSNP
rs1214271443 8694 dbSNP
rs1431373275 8701 dbSNP
rs1273936557 8703 dbSNP
rs996439759 8714 dbSNP
rs901021258 8722 dbSNP
rs1257636127 8730 dbSNP
rs1197006674 8745 dbSNP
rs544311386 8752 dbSNP
rs541681963 8753 dbSNP
rs953452394 8760 dbSNP
rs999074633 8766 dbSNP
rs1032250878 8768 dbSNP
rs1446847672 8769 dbSNP
rs960203427 8771 dbSNP
rs1485309392 8779 dbSNP
rs992914021 8780 dbSNP
rs1402563333 8782 dbSNP
rs1171769185 8788 dbSNP
rs1464414857 8792 dbSNP
rs1259079750 8795 dbSNP
rs1007550515 8802 dbSNP
rs1032303200 8806 dbSNP
rs973386854 8807 dbSNP
rs957993088 8828 dbSNP
rs1237676798 8837 dbSNP
rs1176927959 8840 dbSNP
rs1185615516 8842 dbSNP
rs1257202903 8845 dbSNP
rs1444353540 8845 dbSNP
rs562687872 8846 dbSNP
rs1343365065 8853 dbSNP
rs111883953 8859 dbSNP
rs1288758573 8876 dbSNP
rs1241536847 8877 dbSNP
rs530185915 8882 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.859 6.2e-7 0.826 3.6e-6 20 Click to see details
GSE35602 Colorectal cancer stromal tissue 0.529 3.3e-3 0.485 7.0e-3 25 Click to see details
GSE19536 Breast cancer 0.198 2.4e-2