miRTarBase - #MIRT026027


—
pre-miRNA Information
pre-miRNA hsa-mir-196a-1   
Genomic Coordinates chr17: 48632490 - 48632559
Synonyms MIRN196-1, MIRN196A1, MIR196A1
Description Homo sapiens miR-196a-1 stem-loop
Comment Lagos-Quintana et al. .
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-mir-196a-2   
Genomic Coordinates chr12: 53991738 - 53991847
Synonyms MIRN196-2, MIRN196A2, MIR196A2
Description Homo sapiens miR-196a-2 stem-loop
Comment This human miRNA was predicted by computational methods using conservation with mouse and Fugu rubripes sequences .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-196a-5p
Sequence 25| UAGGUAGUUUCAUGUUGUUGGG |46
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 6 17 - 48632548 29233923 MiREDiBase
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN30188818 11 COSMIC
COSN30130427 18 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1449318187 1 dbSNP
rs1167097656 4 dbSNP
rs767877229 4 dbSNP
rs750731061 10 dbSNP
rs756640169 12 dbSNP
rs931027203 13 dbSNP
rs185070757 13 dbSNP
rs569910454 16 dbSNP
rs190478598 17 dbSNP
rs755062780 17 dbSNP
rs751887895 18 dbSNP
rs1422312414 20 dbSNP
rs372978481 21 dbSNP
rs1289240119 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol PDCD4   
Synonyms H731
Description programmed cell death 4
Transcript NM_014456   
Other Transcripts NM_145341   
Expression
Putative miRNA Targets on PDCD4
3'UTR of PDCD4
(miRNA target sites are highlighted)		 
>PDCD4|NM_014456|3'UTR
   1 ATATAAGAACTCTTGCAGTCTTAGATGTTATAAAAATATATATCTGAATTGTAAGAGTTGTTAGCACAAGTTTTTTTTTT
  81 TTTTTTTTTTAAGCACTTGTTTTGGGTACAAGGCATTTCTGACATTTTATAAACCTACATTTAAGGGGAATTTTTAAAGG
 161 AAATGTTTTTTCTTTTTTTTTTGTTTTTCGAGGGGGCAAGGAGGGACAGAAAAGTAACCTCTTCTTAAGTGGAATATTCT
 241 AATAAGCTACCTTTTGTAAGTGCCATGTTTATTATCTAATCATTCCAAGTTTTGCATTGATGTCTGACTGCCACTCCTTT
 321 CTTTCAAGGACAGTGTTTTTTGTAGTAAAATCACTGGTTTATACAAAGCTTTATTTAGGGGGTAAAGTTAAGCTGCTAAA
 401 ACCCCATGTTGGCTGCTGCTGTTGAGATACTGTGCTTTGGGAGTAAAAAAAGAAAGTTATTTCTTTGTCTTAAAGAATTT
 481 TTAAAAAATTAGTCATGAGACTTATTCATCTTTCCAGGGAACATACTGATTGGTCTTAAAAGACTAGACAGTTAAGTAAA
 561 AGGTGGCTGGAACATCTATTTTTCTACAAAACTGGAAAAATGAACCTGGTTCTAGAAGAATGTACACCAAAATAAAACAT
 641 GTGAAGCAGTATTGATTCTTTATTGGGAGTACATTTTTTTAGGTCTCTTAAACTTTAATTTCACACAGTAAATTTTGAAT
 721 CTCATAAGGAAGCATATTTGAACCTAGTCAATTTAATCTTAGTGTTCCCTTGAAAACTTTTTTTCCCTACAAAATTTTAA
 801 GTGAAAAATACAATAGTAAATTAAGATTACACTGGGGAAAAAAATGCAGGTATCACTTTACTCCATTGTTATCTGACCTA
 881 GAGCTTAATTAAGTTTTAGAAATATGTAATACCTTCCATCATTCCATCATCCTTAAATTCTGTTACCAAATAATGGCTAA
 961 TGTTACAAAAAGTTATACTCCAGAGACCCAAAGCTTGACATTTACCTAATGTATGAGAAAATATTACCAATTAACAATAA
1041 AGAATGATCATATTTTTAACCTCTTTTACATAGCCTAATAACTCAGCAAGGCCTCAACGTCTGTGCTAATTTAAACTGCC
1121 AAATATTGACTGCAGCAAACAAGAATTATATTCAGAATTTATGAGGGTACTGTTAGGAGTATACTGCTTACAGGTTTAGA
1201 TATAGTCTGTTAGAATTAAAACCAAGTTTAGTGTTCATATTTACCTCATGGGCTTTATCAAGCCCATATTACCTCAGCTT
1281 ATATATAGTTACCATTTTTAGGTTTTTAATTGTTTGACACTTGGATGATAAATGCAGTCATTTTATTCTCAAGTGCTTAA
1361 AATTAATGTAATTAAAAGCTTAGCTGACTACAGAATAGGTGAGGGTTTCTTAAAAATGAGATTTAAGGGCTGGGCACGGT
1441 GGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGAGGTTGGGAGTTCATGACCAGCTTGA
1521 CCAACATGAAGAAACCCTGTCTCTATTAAAAATACAAAAGTAGCCAGGCATGGTGGCGCATGCGTGTAATCCCAGCTACT
1601 TGGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGCAGAGGTTGCAGTGAGTCGAGATGGTGCCATTGCTCTCGTT
1681 TGGGCAACAAGAGTGAAACTCTTGTCTCAAAAAAAAAAAAAAATGAGGTTTAAGACAGTTTTGTCATTACTGGTGGGATC
1761 TGGTCACACAAGATAGCATTAAACGTGACATGGCACATAAAATTGGTTAAAAAATTTTGTTTTTTAATTACGTAATGTAA
1841 AAGCCCAACAAACACTTTATGCAAGATTGGAATGTATCTTCAAATTCAGATTTAATAAACATGTAAAGATCCTCTGTAAA
1921 AAAAAAAAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gggUUGUUG---UACUUUGAUGGAu 5'
             ||:| :   || ||:|||||| 
Target 5' tggAATATTCTAAT-AAGCTACCTt 3'
 230 - 253 138.00 -11.20
2 
miRNA  3' ggGUUGUUGUACUUUGAUGGAu 5'
            |||   |||   |:||||| 
Target 5' atCAAGCCCAT---ATTACCTc 3'
 1257 - 1275 133.00 -10.00
3 
miRNA  3' ggGUUGUUGUACUUUGAUGGAu 5'
            :|: ||:|||  | ||||| 
Target 5' ttTAGAAATATG-TAATACCTt 3'
 895 - 915 127.00 -10.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30513930 41 COSMIC
COSN20077120 61 COSMIC
COSN31586225 62 COSMIC
COSN20107546 90 COSMIC
COSN20077167 91 COSMIC
COSN1112386 124 COSMIC
COSN31586717 163 COSMIC
COSN29083098 183 COSMIC
COSN6056641 348 COSMIC
COSN31589683 369 COSMIC
COSN1112388 373 COSMIC
COSN31577787 380 COSMIC
COSN31569900 453 COSMIC
COSN31534635 476 COSMIC
COSN8149300 579 COSMIC
COSN27555657 1066 COSMIC
COSN6056642 1123 COSMIC
COSN29854732 1331 COSMIC
COSN1471208 1485 COSMIC
COSN20788217 1516 COSMIC
COSN8149301 1520 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs780773533 1 dbSNP
rs192041921 4 dbSNP
rs372012361 5 dbSNP
rs1274530692 8 dbSNP
rs780271274 11 dbSNP
rs1461423681 13 dbSNP
rs749729920 14 dbSNP
rs1252920446 16 dbSNP
rs201739274 17 dbSNP
rs774971106 25 dbSNP
rs748132091 28 dbSNP
rs773643180 28 dbSNP
rs1235425484 29 dbSNP
rs1473481400 31 dbSNP
rs1034503022 32 dbSNP
rs1389478794 33 dbSNP
rs12263197 36 dbSNP
rs1427668941 37 dbSNP
rs376964203 40 dbSNP
rs760994347 41 dbSNP
rs1293533284 50 dbSNP
rs766763981 52 dbSNP
rs1177722312 54 dbSNP
rs1481462408 57 dbSNP
rs945794629 59 dbSNP
rs1254056882 60 dbSNP
rs775140901 61 dbSNP
rs762843302 63 dbSNP
rs763911359 65 dbSNP
rs1296880355 66 dbSNP
rs751537495 68 dbSNP
rs1491521147 70 dbSNP
rs759575771 70 dbSNP
rs761257424 70 dbSNP
rs771292422 70 dbSNP
rs1375667883 71 dbSNP
rs397716645 71 dbSNP
rs5787876 71 dbSNP
rs763160233 71 dbSNP
rs775747835 71 dbSNP
rs776805156 71 dbSNP
rs977086596 71 dbSNP
rs1175129960 74 dbSNP
rs767018039 75 dbSNP
rs750018222 76 dbSNP
rs1344721798 79 dbSNP
rs779798593 81 dbSNP
rs1014210812 87 dbSNP
rs1186940826 91 dbSNP
rs1276051599 91 dbSNP
rs1489992836 91 dbSNP
rs757243971 91 dbSNP
rs1222273709 92 dbSNP
rs1269984987 97 dbSNP
rs1002808943 100 dbSNP
rs749594671 103 dbSNP
rs1192500325 105 dbSNP
rs755392885 106 dbSNP
rs1427468584 107 dbSNP
rs779252577 110 dbSNP
rs1170528262 112 dbSNP
rs556498033 114 dbSNP
rs577882072 115 dbSNP
rs1311283326 130 dbSNP
rs72819730 134 dbSNP
rs1032781331 139 dbSNP
rs1314276292 146 dbSNP
rs1397780523 148 dbSNP
rs1383835412 152 dbSNP
rs554044351 153 dbSNP
rs373862908 158 dbSNP
rs749268636 160 dbSNP
rs1366639391 161 dbSNP
rs1164132811 163 dbSNP
rs1475380272 166 dbSNP
rs1010397344 167 dbSNP
rs1190280165 169 dbSNP
rs1205781530 173 dbSNP
rs1261363981 173 dbSNP
rs138010548 173 dbSNP
rs1486930275 173 dbSNP
rs550230568 173 dbSNP
rs1213640065 180 dbSNP
rs1052550 182 dbSNP
rs1421546024 183 dbSNP
rs1225757702 184 dbSNP
rs966695346 184 dbSNP
rs543153032 190 dbSNP
rs976398998 191 dbSNP
rs1418147360 201 dbSNP
rs1387967989 207 dbSNP
rs12248739 215 dbSNP
rs1167597601 219 dbSNP
rs548643783 219 dbSNP
rs1396652128 220 dbSNP
rs1168248170 240 dbSNP
rs953420949 242 dbSNP
rs1461752056 244 dbSNP
rs1194177840 249 dbSNP
rs1299250990 257 dbSNP
rs1251247168 258 dbSNP
rs1399213623 261 dbSNP
rs1469284066 263 dbSNP
rs1394389347 268 dbSNP
rs146211346 270 dbSNP
rs1339142667 276 dbSNP
rs1251468960 285 dbSNP
rs529863924 287 dbSNP
rs1229185213 293 dbSNP
rs921091660 294 dbSNP
rs768075579 298 dbSNP
rs61469604 303 dbSNP
rs940800810 309 dbSNP
rs1306720036 310 dbSNP
rs756545115 311 dbSNP
rs1409090372 323 dbSNP
rs1396971995 332 dbSNP
rs1168667096 333 dbSNP
rs1463689523 335 dbSNP
rs368483051 336 dbSNP
rs746143494 364 dbSNP
rs1454815676 365 dbSNP
rs1255365411 369 dbSNP
rs1036344767 374 dbSNP
rs1209586899 379 dbSNP
rs1437561198 380 dbSNP
rs1257563402 382 dbSNP
rs1345268277 386 dbSNP
rs1476020013 387 dbSNP
rs1191038232 388 dbSNP
rs1279237536 398 dbSNP
rs1394888963 406 dbSNP
rs899189743 408 dbSNP
rs1349430458 409 dbSNP
rs1277645062 419 dbSNP
rs1336314793 420 dbSNP
rs1441424023 420 dbSNP
rs1330610619 425 dbSNP
rs1373862892 431 dbSNP
rs995078972 442 dbSNP
rs1435356761 448 dbSNP
rs1396989471 451 dbSNP
rs1157300179 460 dbSNP
rs72819732 470 dbSNP
rs905502907 476 dbSNP
rs958946663 476 dbSNP
rs11548764 485 dbSNP
rs1184412616 489 dbSNP
rs1171507735 501 dbSNP
rs1375338553 502 dbSNP
rs1256289038 504 dbSNP
rs1433368499 506 dbSNP
rs796971952 518 dbSNP
rs1376130997 519 dbSNP
rs1281481400 520 dbSNP
rs1054152305 524 dbSNP
rs1351290183 531 dbSNP
rs1416634506 540 dbSNP
rs1231152880 548 dbSNP
rs1354595918 550 dbSNP
rs1312449120 557 dbSNP
rs1361159956 560 dbSNP
rs1415660391 560 dbSNP
rs1316288062 569 dbSNP
rs1400255863 574 dbSNP
rs892875475 579 dbSNP
rs1162010579 587 dbSNP
rs1010030514 588 dbSNP
rs1361479457 599 dbSNP
rs1214962786 606 dbSNP
rs1297423318 610 dbSNP
rs1020458751 613 dbSNP
rs1240057210 614 dbSNP
rs1214449027 619 dbSNP
rs1447082126 619 dbSNP
rs1286187826 621 dbSNP
rs1211765099 626 dbSNP
rs1467628372 629 dbSNP
rs1333829858 635 dbSNP
rs759553259 639 dbSNP
rs1233463322 641 dbSNP
rs1381601649 646 dbSNP
rs1280489142 647 dbSNP
rs998150940 650 dbSNP
rs1268710457 659 dbSNP
rs1430030649 662 dbSNP
rs1486371655 672 dbSNP
rs1029257908 674 dbSNP
rs1323085965 677 dbSNP
rs1460370318 681 dbSNP
rs1394452365 686 dbSNP
rs953785133 691 dbSNP
rs1407499706 711 dbSNP
rs1416863901 713 dbSNP
rs984736615 716 dbSNP
rs1024492157 718 dbSNP
rs1016256413 725 dbSNP
rs761358804 727 dbSNP
rs967132003 729 dbSNP
rs532537004 734 dbSNP
rs139237079 738 dbSNP
rs972129810 745 dbSNP
rs1173577363 746 dbSNP
rs565963166 750 dbSNP
rs1214233230 758 dbSNP
rs957299247 762 dbSNP
rs866368294 765 dbSNP
rs1299886324 770 dbSNP
rs975301420 775 dbSNP
rs1438870762 778 dbSNP
rs949933576 778 dbSNP
rs1436694386 782 dbSNP
rs1353143165 786 dbSNP
rs1169261968 787 dbSNP
rs1156949087 790 dbSNP
rs921142646 791 dbSNP
rs1391686042 793 dbSNP
rs1171185490 804 dbSNP
rs1453342679 810 dbSNP
rs933920544 814 dbSNP
rs1253476559 815 dbSNP
rs1192866878 825 dbSNP
rs981737163 826 dbSNP
rs1431710867 829 dbSNP
rs1205013967 834 dbSNP
rs1050859596 839 dbSNP
rs56875008 858 dbSNP
rs1232087130 860 dbSNP
rs940770586 862 dbSNP
rs1347260445 865 dbSNP
rs1439811981 872 dbSNP
rs1304743483 877 dbSNP
rs1304112024 878 dbSNP
rs1389067216 879 dbSNP
rs1054121612 885 dbSNP
rs1297941842 888 dbSNP
rs376183497 890 dbSNP
rs72377323 890 dbSNP
rs747522218 890 dbSNP
rs549069926 894 dbSNP
rs1036886771 901 dbSNP
rs1237391718 919 dbSNP
rs1310703143 926 dbSNP
rs899161298 927 dbSNP
rs1433500110 932 dbSNP
rs1395185722 950 dbSNP
rs373508013 960 dbSNP
rs1407235544 961 dbSNP
rs1417208347 961 dbSNP
rs994799070 962 dbSNP
rs531826405 968 dbSNP
rs1282905790 970 dbSNP
rs1317214605 977 dbSNP
rs796147119 981 dbSNP
rs1244565042 986 dbSNP
rs1485361887 990 dbSNP
rs1341930842 995 dbSNP
rs1256632329 1007 dbSNP
rs1041503944 1008 dbSNP
rs901977228 1011 dbSNP
rs571420900 1013 dbSNP
rs894701212 1014 dbSNP
rs1413826408 1019 dbSNP
rs537866454 1029 dbSNP
rs1269091786 1039 dbSNP
rs1304061122 1039 dbSNP
rs1344463009 1043 dbSNP
rs1175594613 1050 dbSNP
rs1014533843 1059 dbSNP
rs1415433303 1061 dbSNP
rs1473421423 1061 dbSNP
rs1407340708 1067 dbSNP
rs796343911 1072 dbSNP
rs1257198173 1073 dbSNP
rs1202245029 1076 dbSNP
rs1484937899 1078 dbSNP
rs1315592630 1080 dbSNP
rs367711802 1080 dbSNP
rs568306693 1080 dbSNP
rs1331622994 1081 dbSNP
rs962020555 1097 dbSNP
rs745440231 1098 dbSNP
rs972098737 1099 dbSNP
rs1355688308 1100 dbSNP
rs1314431931 1105 dbSNP
rs1161567474 1106 dbSNP
rs967980002 1109 dbSNP
rs1379965358 1111 dbSNP
rs2146544 1119 dbSNP
rs143977617 1132 dbSNP
rs1392260035 1141 dbSNP
rs1458719530 1141 dbSNP
rs1033217144 1146 dbSNP
rs1461828075 1153 dbSNP
rs1369205435 1158 dbSNP
rs1326311133 1161 dbSNP
rs957148553 1166 dbSNP
rs1373154558 1179 dbSNP
rs971248810 1180 dbSNP
rs1261170021 1189 dbSNP
rs1189344889 1190 dbSNP
rs975018707 1191 dbSNP
rs981281339 1193 dbSNP
rs1278505215 1197 dbSNP
rs1213381496 1201 dbSNP
rs1373445108 1202 dbSNP
rs115021775 1204 dbSNP
rs958605891 1205 dbSNP
rs990076859 1207 dbSNP
rs914204576 1210 dbSNP
rs1333642953 1227 dbSNP
rs1436718766 1233 dbSNP
rs775616314 1241 dbSNP
rs1325145977 1244 dbSNP
rs1441291023 1250 dbSNP
rs116669104 1252 dbSNP
rs1165182596 1258 dbSNP
rs1460632964 1259 dbSNP
rs572244618 1264 dbSNP
rs1451409709 1269 dbSNP
rs923025458 1277 dbSNP
rs1193579254 1279 dbSNP
rs532881191 1285 dbSNP
rs1194487317 1286 dbSNP
rs1050607723 1289 dbSNP
rs117501349 1292 dbSNP
rs973935747 1293 dbSNP
rs1345137187 1294 dbSNP
rs576331563 1300 dbSNP
rs1470554249 1303 dbSNP
rs1233923377 1310 dbSNP
rs1302527597 1310 dbSNP
rs920641886 1313 dbSNP
rs1326585305 1316 dbSNP
rs1416027735 1319 dbSNP
rs1390666987 1320 dbSNP
rs897802703 1326 dbSNP
rs1474987377 1330 dbSNP
rs571704165 1345 dbSNP
rs1165468211 1348 dbSNP
rs930727918 1351 dbSNP
rs1396393823 1355 dbSNP
rs535870892 1357 dbSNP
rs1055780881 1358 dbSNP
rs894504715 1363 dbSNP
rs950268884 1364 dbSNP
rs993447482 1365 dbSNP
rs1379939259 1366 dbSNP
rs543427963 1367 dbSNP
rs1328106739 1369 dbSNP
rs1437682329 1369 dbSNP
rs1206910800 1371 dbSNP
rs768527963 1372 dbSNP
rs903350635 1374 dbSNP
rs760414646 1376 dbSNP
rs1278939229 1377 dbSNP
rs184164741 1385 dbSNP
rs763246128 1393 dbSNP
rs958532831 1397 dbSNP
rs532647939 1403 dbSNP
rs1290877178 1404 dbSNP
rs1289189660 1405 dbSNP
rs892861715 1410 dbSNP
rs914476331 1417 dbSNP
rs1233514747 1419 dbSNP
rs996573900 1423 dbSNP
rs867314467 1429 dbSNP
rs541373922 1434 dbSNP
rs146414879 1438 dbSNP
rs188713884 1439 dbSNP
rs922962287 1448 dbSNP
rs1184824515 1452 dbSNP
rs1473991969 1453 dbSNP
rs1475087791 1457 dbSNP
rs1256381142 1464 dbSNP
rs1210122140 1465 dbSNP
rs1443703773 1476 dbSNP
rs1258448635 1477 dbSNP
rs1015886528 1484 dbSNP
rs1272955212 1485 dbSNP
rs961325608 1486 dbSNP
rs974284621 1489 dbSNP
rs774549387 1492 dbSNP
rs910691078 1499 dbSNP
rs919788416 1503 dbSNP
rs930696809 1510 dbSNP
rs991600931 1517 dbSNP
rs1316811264 1522 dbSNP
rs548773635 1522 dbSNP
rs915907321 1527 dbSNP
rs950071375 1532 dbSNP
rs1037856868 1536 dbSNP
rs1188942375 1537 dbSNP
rs1412609944 1538 dbSNP
rs1182140294 1539 dbSNP
rs1420208111 1539 dbSNP
rs1473478135 1544 dbSNP
rs1474322629 1545 dbSNP
rs898068979 1554 dbSNP
rs1045735530 1556 dbSNP
rs1465247978 1561 dbSNP
rs993744051 1569 dbSNP
rs903401797 1575 dbSNP
rs377721423 1578 dbSNP
rs1289403011 1582 dbSNP
rs906527793 1585 dbSNP
rs1310614704 1588 dbSNP
rs934945278 1591 dbSNP
rs1414802660 1592 dbSNP
rs1366467780 1599 dbSNP
rs1034191190 1600 dbSNP
rs561051882 1606 dbSNP
rs958134628 1607 dbSNP
rs1165971583 1613 dbSNP
rs55858908 1618 dbSNP
rs1324275923 1620 dbSNP
rs192265483 1623 dbSNP
rs1021504349 1627 dbSNP
rs1191722221 1629 dbSNP
rs149734425 1632 dbSNP
rs1269951480 1647 dbSNP
rs1247026005 1648 dbSNP
rs1340769730 1649 dbSNP
rs1453481319 1654 dbSNP
rs182879722 1656 dbSNP
rs1227752499 1658 dbSNP
rs1278743357 1659 dbSNP
rs1028068006 1660 dbSNP
rs11548763 1664 dbSNP
rs145626064 1678 dbSNP
rs1232697157 1679 dbSNP
rs1211639143 1685 dbSNP
rs1258557671 1686 dbSNP
rs1445472299 1687 dbSNP
rs1192252744 1689 dbSNP
rs1367550079 1689 dbSNP
rs1294429727 1691 dbSNP
rs187023714 1694 dbSNP
rs1476382871 1695 dbSNP
rs1171696543 1701 dbSNP
rs985875614 1702 dbSNP
rs1307089275 1703 dbSNP
rs1394327171 1705 dbSNP
rs1429801064 1708 dbSNP
rs1434828084 1708 dbSNP
rs1491333548 1708 dbSNP
rs754057095 1708 dbSNP
rs1204760448 1709 dbSNP
rs1249869792 1709 dbSNP
rs1420323869 1709 dbSNP
rs1483525287 1709 dbSNP
rs200583503 1709 dbSNP
rs201736448 1709 dbSNP
rs537232273 1709 dbSNP
rs1015272907 1711 dbSNP
rs1382380498 1712 dbSNP
rs961565790 1723 dbSNP
rs1318149006 1724 dbSNP
rs1475634434 1725 dbSNP
rs941813166 1726 dbSNP
rs973533031 1729 dbSNP
rs1301926492 1730 dbSNP
rs1410013506 1737 dbSNP
rs919464628 1742 dbSNP
rs1396238820 1750 dbSNP
rs974041950 1752 dbSNP
rs565692123 1759 dbSNP
rs929534218 1770 dbSNP
rs1047092035 1771 dbSNP
rs1348891381 1773 dbSNP
rs558844759 1780 dbSNP
rs554731075 1785 dbSNP
rs1182664658 1786 dbSNP
rs577554924 1794 dbSNP
rs1254253150 1797 dbSNP
rs1180188349 1804 dbSNP
rs1191469549 1807 dbSNP
rs1252318986 1815 dbSNP
rs1454637875 1816 dbSNP
rs1212911329 1818 dbSNP
rs991569865 1822 dbSNP
rs915959835 1826 dbSNP
rs1267842582 1828 dbSNP
rs754084731 1832 dbSNP
rs576468849 1833 dbSNP
rs1394930265 1835 dbSNP
rs757693138 1837 dbSNP
rs1021430769 1838 dbSNP
rs1451482480 1839 dbSNP
rs569691826 1841 dbSNP
rs998754097 1845 dbSNP
rs1386634026 1852 dbSNP
rs537134116 1859 dbSNP
rs558527459 1861 dbSNP
rs1163010892 1875 dbSNP
rs1423286685 1879 dbSNP
rs764810501 1879 dbSNP
rs34559036 1881 dbSNP
rs986187058 1892 dbSNP
rs1463887438 1901 dbSNP
rs1247952586 1912 dbSNP
rs1209742766 1915 dbSNP
rs1263288517 1917 dbSNP
rs1331728099 1917 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE14794 Lymphoblastoid cells -0.278 4.0e-3 -0.229 1.5e-2 90 Click to see details
GSE17498 Multiple myeloma -0.242 6.6e-2 -0.096 2.8e-1 40 Click to see details
GSE21849 B cell lymphoma 0.253 9.3e-2 0.265 8.2e-2 29 Click to see details
GSE19536 Breast cancer 0.133 9.4e-2 0.109 1.4e-1 100 Click to see details
GSE28260 Renal cortex and medulla -0.383 9.8e-2 -0.280 1.8e-1 13 Click to see details
GSE19783 ER+ ER+ breast cancer 0.301 9.9e-2 0.277 1.2e-1 20 Click to see details
GSE27834 Pluripotent stem cells 0.323 1.1e-1 0.197 2.3e-1 16 Click to see details
GSE19350 CNS germ cell tumors -0.37 1.2e-1 -0.259 2.1e-1 12 Click to see details
GSE19783 ER- ER- breast cancer 0.115 1.6e-1 0.080 2.4e-1 79 Click to see details
GSE42095 Differentiated embryonic stem cells 0.174 2.1e-1 0.407 2.7e-2 23 Click to see details
GSE28544 Breast cancer 0.167 2.2e-1 0.029 4.5e-1 24 Click to see details
GSE38226 Liver fibrosis 0.142 2.7e-1 0.327 7.4e-2 21 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.13 2.9e-1 -0.314 8.9e-2 20 Click to see details
GSE21032 Prostate cancer -0.059 3.0e-1 -0.035 3.8e-1 83 Click to see details
GSE17306 Multiple myeloma -0.07 3.2e-1 0.072 3.1e-1 49 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.1 3.2e-1 0.028 4.5e-1 25 Click to see details
GSE35602 Colorectal cancer stromal tissue 0.074 3.6e-1 0.118 2.9e-1 25 Click to see details
GSE26953 Aortic valvular endothelial cells -0.068 3.8e-1 0.139 2.6e-1 24 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.1 4.0e-1 0.050 4.5e-1 9 Click to see details
GSE32688 Pancreatic cancer -0.028 4.4e-1 -0.033 4.3e-1 32 Click to see details
GSE21687 Ependynoma primary tumors 0.015 4.5e-1 0.235 3.1e-2 64 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
BRCA 0.249 0.01 0.232 0.02 84 Click to see details
HNSC -0.3 0.03 -0.273 0.04 42 Click to see details
PAAD -0.906 0.05 -0.200 0.4 4 Click to see details
STAD -0.246 0.09 -0.292 0.06 31 Click to see details
COAD 0.518 0.09 0.357 0.19 8 Click to see details
THCA -0.171 0.13 -0.199 0.09 47 Click to see details
KIRC -0.121 0.16 -0.070 0.29 68 Click to see details
LUSC -0.163 0.16 -0.250 0.07 38 Click to see details
BLCA -0.24 0.17 -0.195 0.22 18 Click to see details
ESCA -0.318 0.17 -0.264 0.22 11 Click to see details
LUAD -0.246 0.23 -0.091 0.4 11 Click to see details
LIHC 0.087 0.3 0.153 0.18 37 Click to see details
CESC 0.523 0.32 0.500 0.33 3 Click to see details
KIRP -0.075 0.34 0.030 0.44 32 Click to see details
PRAD 0.046 0.38 0.075 0.3 50 Click to see details
UCEC -0.038 0.44 -0.014 0.48 19 Click to see details
CHOL 0.008 0.49 -0.095 0.41 8 Click to see details
KICH -0.003 0.49 -0.072 0.37 25 Click to see details
PCPG -1 0.5 -1.000 0.5 3 Click to see details
PCPG -1 0.5 -1.000 0.5 3 Click to see details
PCPG -1 0.5 -1.000 0.5 3 Click to see details
301 hsa-miR-196a-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT000218 BMP4 bone morphogenetic protein 4 1 1
MIRT000219 SPRR2C small proline rich protein 2C (pseudogene) 3 2
MIRT000220 S100A9 S100 calcium binding protein A9 3 2
MIRT000221 KRT5 keratin 5 3 2
MIRT000709 ANXA1 annexin A1 4 2
MIRT002266 HOXB8 homeobox B8 5 7
MIRT002940 HOXA7 homeobox A7 4 5
MIRT002941 HOXD8 homeobox D8 3 3
MIRT002942 HOXC8 homeobox C8 6 15
MIRT004244 HOXB7 homeobox B7 4 1
MIRT004718 BACH1 BTB domain and CNC homolog 1 6 3
MIRT004719 HMOX1 heme oxygenase 1 4 1
MIRT005065 CDKN1B cyclin dependent kinase inhibitor 1B 6 7
MIRT006802 HMGA1 high mobility group AT-hook 1 5 5
MIRT006803 HMGA2 high mobility group AT-hook 2 5 7
MIRT006906 HOXA5 homeobox A5 5 3
MIRT026026 IKBKB inhibitor of nuclear factor kappa B kinase subunit beta 1 1
MIRT026027 PDCD4 programmed cell death 4 1 1
MIRT026028 SRRT serrate, RNA effector molecule 2 9
MIRT026029 DIEXF digestive organ expansion factor homolog (zebrafish) 1 1
MIRT026030 ZBTB24 zinc finger and BTB domain containing 24 1 1
MIRT026031 NR4A1 nuclear receptor subfamily 4 group A member 1 1 1
MIRT026032 ABT1 activator of basal transcription 1 1 1
MIRT026033 SPATA2 spermatogenesis associated 2 1 1
MIRT026034 NHLRC3 NHL repeat containing 3 1 1
MIRT026035 RPUSD2 RNA pseudouridylate synthase domain containing 2 1 1
MIRT026036 CEP120 centrosomal protein 120 1 1
MIRT026037 PHC3 polyhomeotic homolog 3 1 1
MIRT026038 ZBTB6 zinc finger and BTB domain containing 6 1 1
MIRT026039 C9orf41 carnosine N-methyltransferase 1 1 1
MIRT026040 PNP purine nucleoside phosphorylase 1 1
MIRT026041 COPS3 COP9 signalosome subunit 3 1 1
MIRT026042 NUP50 nucleoporin 50 1 1
MIRT026043 ZNF763 zinc finger protein 763 1 1
MIRT026044 FOXJ3 forkhead box J3 1 1
MIRT026045 BIN3 bridging integrator 3 1 1
MIRT026046 C12orf4 chromosome 12 open reading frame 4 1 1
MIRT026047 RAD9A RAD9 checkpoint clamp component A 1 1
MIRT026048 PCGF3 polycomb group ring finger 3 1 1
MIRT026049 KATNAL1 katanin catalytic subunit A1 like 1 1 1
MIRT026050 SLC10A7 solute carrier family 10 member 7 1 1
MIRT026051 LBR lamin B receptor 1 1
MIRT026052 BCL11A B-cell CLL/lymphoma 11A 1 1
MIRT026053 GLMN glomulin, FKBP associated protein 1 1
MIRT026054 STK40 serine/threonine kinase 40 1 1
MIRT026055 TMEM135 transmembrane protein 135 1 1
MIRT026056 GGA3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 2 3
MIRT026057 POLR2D RNA polymerase II subunit D 2 5
MIRT026058 LGR4 leucine rich repeat containing G protein-coupled receptor 4 1 1
MIRT026059 IGF2BP3 insulin like growth factor 2 mRNA binding protein 3 2 4
MIRT026060 ESPL1 extra spindle pole bodies like 1, separase 1 1
MIRT026061 RFX5 regulatory factor X5 1 1
MIRT026062 SYT9 synaptotagmin 9 1 1
MIRT026063 PEX13 peroxisomal biogenesis factor 13 1 1
MIRT026064 IGF1R insulin like growth factor 1 receptor 1 1
MIRT026065 SMCR7L mitochondrial elongation factor 1 1 4
MIRT026066 SLC30A6 solute carrier family 30 member 6 2 3
MIRT026067 RAB31 RAB31, member RAS oncogene family 1 1
MIRT026068 KPNA5 karyopherin subunit alpha 5 1 1
MIRT026069 SLC20A1 solute carrier family 20 member 1 1 1
MIRT026070 TIMM23 translocase of inner mitochondrial membrane 23 1 1
MIRT026071 IGDCC4 immunoglobulin superfamily DCC subclass member 4 2 6
MIRT026072 SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 1 1
MIRT026073 CCNT2 cyclin T2 1 1
MIRT026074 CCND2 cyclin D2 1 1
MIRT026075 USP24 ubiquitin specific peptidase 24 1 1
MIRT026076 TRPC3 transient receptor potential cation channel subfamily C member 3 2 4
MIRT026077 SMC3 structural maintenance of chromosomes 3 1 1
MIRT026078 TMEM2 transmembrane protein 2 1 1
MIRT026079 RDH10 retinol dehydrogenase 10 1 1
MIRT026080 C11orf57 chromosome 11 open reading frame 57 2 5
MIRT026081 FAM127A retrotransposon Gag like 8C 2 4
MIRT026082 PRUNE2 prune homolog 2 2 3
MIRT026083 SPRYD4 SPRY domain containing 4 1 1
MIRT026084 TMEM161B transmembrane protein 161B 1 1
MIRT026085 CPEB3 cytoplasmic polyadenylation element binding protein 3 1 1
MIRT026086 FAM104A family with sequence similarity 104 member A 2 2
MIRT026087 RAB7L1 RAB29, member RAS oncogene family 1 1
MIRT026088 ITGAV integrin subunit alpha V 1 1
MIRT026089 CPD carboxypeptidase D 1 1
MIRT026090 ZNF354B zinc finger protein 354B 1 1
MIRT026091 TMEM194A nuclear envelope integral membrane protein 1 1 1
MIRT026092 EPHA7 EPH receptor A7 1 1
MIRT026093 KIAA1804 mitogen-activated protein kinase kinase kinase 21 1 1
MIRT026094 DFFA DNA fragmentation factor subunit alpha 2 2
MIRT026095 TSPAN12 tetraspanin 12 1 1
MIRT026096 LIN28B lin-28 homolog B 1 1
MIRT026097 ARHGAP28 Rho GTPase activating protein 28 1 1
MIRT026098 IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 1 1
MIRT026099 CCDC47 coiled-coil domain containing 47 1 1
MIRT026100 HAND1 heart and neural crest derivatives expressed 1 4 2
MIRT026101 LLGL1 LLGL1, scribble cell polarity complex component 1 1
MIRT048150 PGAM1 phosphoglycerate mutase 1 1 1
MIRT048151 PSMC3 proteasome 26S subunit, ATPase 3 1 1
MIRT048152 TMX2 thioredoxin related transmembrane protein 2 1 1
MIRT048153 KLHL7 kelch like family member 7 1 1
MIRT048154 RFC2 replication factor C subunit 2 1 1
MIRT048155 GLUL glutamate-ammonia ligase 1 1
MIRT048156 NRXN1 neurexin 1 1 1
MIRT048157 GSTK1 glutathione S-transferase kappa 1 1 1
MIRT048158 HIST2H4B histone cluster 2 H4 family member b 1 1
MIRT048159 SPEN spen family transcriptional repressor 1 1
MIRT048160 TAF15 TATA-box binding protein associated factor 15 1 1
MIRT048161 SAP18 Sin3A associated protein 18 1 1
MIRT048162 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 1 1
MIRT048163 MSL3 MSL complex subunit 3 1 1
MIRT048164 TSKU tsukushi, small leucine rich proteoglycan 1 1
MIRT048165 KMT2C lysine methyltransferase 2C 1 1
MIRT048166 LYRM2 LYR motif containing 2 1 1
MIRT048167 UBE2Z ubiquitin conjugating enzyme E2 Z 1 1
MIRT048168 C19orf55 proline and serine rich 3 1 1
MIRT048169 LRP2 LDL receptor related protein 2 1 1
MIRT048170 ND4L NADH dehydrogenase, subunit 4L (complex I) 1 1
MIRT048171 NKX6-1 NK6 homeobox 1 1 1
MIRT048172 BRMS1L breast cancer metastasis-suppressor 1 like 1 1
MIRT048173 RPS2 ribosomal protein S2 1 1
MIRT048174 RBMX RNA binding motif protein, X-linked 1 1
MIRT048175 ZFP64 ZFP64 zinc finger protein 1 1
MIRT048176 REEP2 receptor accessory protein 2 1 1
MIRT048177 MED13 mediator complex subunit 13 1 1
MIRT048178 MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 1 1
MIRT048179 TRAPPC9 trafficking protein particle complex 9 1 1
MIRT048180 DNTTIP2 deoxynucleotidyltransferase terminal interacting protein 2 1 1
MIRT048181 VDAC3 voltage dependent anion channel 3 1 1
MIRT048182 ZNF529 zinc finger protein 529 1 1
MIRT048183 EWSR1 EWS RNA binding protein 1 1 1
MIRT048184 ATP6V1B2 ATPase H+ transporting V1 subunit B2 1 1
MIRT048185 RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 1 1
MIRT048186 APP amyloid beta precursor protein 1 1
MIRT048187 PROSER1 proline and serine rich 1 1 1
MIRT048188 HIST1H2BB histone cluster 1 H2B family member b 1 1
MIRT048189 TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 1 1
MIRT048190 TUBA1B tubulin alpha 1b 1 1
MIRT048191 USP19 ubiquitin specific peptidase 19 1 1
MIRT048192 COX3 cytochrome c oxidase III 1 1
MIRT048193 PSMD8 proteasome 26S subunit, non-ATPase 8 1 1
MIRT048194 TRA2B transformer 2 beta homolog 1 1
MIRT048195 MRPL35 mitochondrial ribosomal protein L35 1 1
MIRT048196 KCTD1 potassium channel tetramerization domain containing 1 1 1
MIRT048197 UBE2C ubiquitin conjugating enzyme E2 C 1 1
MIRT048198 ZNF581 zinc finger protein 581 1 1
MIRT048199 CNOT11 CCR4-NOT transcription complex subunit 11 1 1
MIRT048200 POTEG POTE ankyrin domain family member G 1 1
MIRT048201 MTRF1L mitochondrial translational release factor 1 like 1 1
MIRT048202 SRP9 signal recognition particle 9 2 5
MIRT048203 BCORL1 BCL6 corepressor like 1 1 1
MIRT048204 NRBP1 nuclear receptor binding protein 1 1 1
MIRT048205 LRRC41 leucine rich repeat containing 41 1 1
MIRT048206 ATP6 ATP synthase F0 subunit 6 1 1
MIRT048207 FKTN fukutin 1 1
MIRT048208 RANBP9 RAN binding protein 9 1 1
MIRT048209 SYVN1 synoviolin 1 1 1
MIRT048210 NR2F6 nuclear receptor subfamily 2 group F member 6 1 1
MIRT048211 ATG16L1 autophagy related 16 like 1 1 1
MIRT048212 EIF2S3 eukaryotic translation initiation factor 2 subunit gamma 1 1
MIRT048213 ECHDC1 ethylmalonyl-CoA decarboxylase 1 1 1
MIRT048214 HAUS6 HAUS augmin like complex subunit 6 1 1
MIRT048215 CKAP2L cytoskeleton associated protein 2 like 1 1
MIRT048216 IFNGR1 interferon gamma receptor 1 1 1
MIRT048217 ANXA7 annexin A7 1 1
MIRT048218 ENAH ENAH, actin regulator 1 1
MIRT048219 FOXO1 forkhead box O1 9 3
MIRT048220 NDFIP1 Nedd4 family interacting protein 1 1 1
MIRT048221 LSM14A LSM14A, mRNA processing body assembly factor 1 1
MIRT048222 ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 1 1
MIRT048223 SLC25A17 solute carrier family 25 member 17 1 1
MIRT048224 ZNF398 zinc finger protein 398 1 1
MIRT048225 RASSF7 Ras association domain family member 7 1 1
MIRT048226 SBF1 SET binding factor 1 1 1
MIRT048227 TP53RK TP53 regulating kinase 1 1
MIRT048228 MED12 mediator complex subunit 12 1 1
MIRT048229 FLNA filamin A 1 1
MIRT048230 CCNE2 cyclin E2 1 1
MIRT048231 CANX calnexin 1 1
MIRT048232 PRPF8 pre-mRNA processing factor 8 1 1
MIRT048233 FRS2 fibroblast growth factor receptor substrate 2 1 1
MIRT048234 KIF18B kinesin family member 18B 1 1
MIRT048235 U2AF2 U2 small nuclear RNA auxiliary factor 2 1 1
MIRT048236 SH3GL3 SH3 domain containing GRB2 like 3, endophilin A3 1 1
MIRT048237 VCP valosin containing protein 1 1
MIRT048238 ETV3 ETS variant 3 1 1
MIRT048239 BCS1L BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone 1 1
MIRT048240 ND5 NADH dehydrogenase, subunit 5 (complex I) 1 1
MIRT048241 ZCCHC11 zinc finger CCHC-type containing 11 1 1
MIRT048242 RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 1 1
MIRT048243 HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 1 1
MIRT048244 ACTB actin beta 1 1
MIRT048245 UQCRC2 ubiquinol-cytochrome c reductase core protein II 1 1
MIRT048246 EIF2B4 eukaryotic translation initiation factor 2B subunit delta 1 1
MIRT048247 GMFB glia maturation factor beta 1 1
MIRT048248 PALLD palladin, cytoskeletal associated protein 1 1
MIRT048249 CASP3 caspase 3 1 1
MIRT048250 VCL vinculin 1 1
MIRT048251 IPO5 importin 5 1 1
MIRT048252 PATL1 PAT1 homolog 1, processing body mRNA decay factor 1 1
MIRT048253 NAP1L4 nucleosome assembly protein 1 like 4 1 1
MIRT048254 RUFY2 RUN and FYVE domain containing 2 2 1
MIRT048255 TUBB tubulin beta class I 1 1
MIRT048256 CCND1 cyclin D1 1 1
MIRT048257 GID8 GID complex subunit 8 homolog 1 1
MIRT048258 VDAC2 voltage dependent anion channel 2 1 1
MIRT048259 SLC6A8 solute carrier family 6 member 8 1 1
MIRT048260 FXR2 FMR1 autosomal homolog 2 1 1
MIRT048261 SCN11A sodium voltage-gated channel alpha subunit 11 1 1
MIRT048262 AHSA1 activator of HSP90 ATPase activity 1 1 1
MIRT048263 ATG9A autophagy related 9A 1 1
MIRT048264 NOTCH2 notch 2 1 1
MIRT048265 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 1 1
MIRT048266 ND4 NADH dehydrogenase, subunit 4 (complex I) 2 1
MIRT048267 OAT ornithine aminotransferase 1 1
MIRT048268 TRAP1 TNF receptor associated protein 1 1 1
MIRT048269 SKI SKI proto-oncogene 1 1
MIRT048270 GLTP glycolipid transfer protein 1 1
MIRT048271 EEF2 eukaryotic translation elongation factor 2 1 1
MIRT048272 LSM3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated 1 1
MIRT048273 GRIK4 glutamate ionotropic receptor kainate type subunit 4 1 1
MIRT048274 PDE6D phosphodiesterase 6D 1 1
MIRT048275 MPP2 membrane palmitoylated protein 2 1 1
MIRT048276 SAR1B secretion associated Ras related GTPase 1B 2 3
MIRT048277 MAP4 microtubule associated protein 4 1 1
MIRT048278 RAB21 RAB21, member RAS oncogene family 1 1
MIRT048279 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 1 1
MIRT048280 OGFRL1 opioid growth factor receptor like 1 1 1
MIRT048281 GOT2 glutamic-oxaloacetic transaminase 2 1 1
MIRT048282 NRDE2 NRDE-2, necessary for RNA interference, domain containing 1 1
MIRT048283 SBNO1 strawberry notch homolog 1 1 1
MIRT053067 NTN4 netrin 4 2 1
MIRT054025 RDX radixin 5 5
MIRT056750 ARID5B AT-rich interaction domain 5B 2 2
MIRT057645 LCOR ligand dependent nuclear receptor corepressor 2 4
MIRT076226 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 6
MIRT083303 ZCCHC3 zinc finger CCHC-type containing 3 2 2
MIRT095769 GRPEL2 GrpE like 2, mitochondrial 2 10
MIRT187720 SUOX sulfite oxidase 2 2
MIRT191923 CALM1 calmodulin 1 2 2
MIRT205504 SP100 SP100 nuclear antigen 2 2
MIRT209857 ACVR2B activin A receptor type 2B 2 2
MIRT229841 YIPF6 Yip1 domain family member 6 2 2
MIRT230833 TBRG1 transforming growth factor beta regulator 1 2 2
MIRT235376 CALM3 calmodulin 3 2 2
MIRT251626 KCNJ2 potassium voltage-gated channel subfamily J member 2 2 2
MIRT252333 SALL3 spalt like transcription factor 3 2 2
MIRT255317 CDV3 CDV3 homolog 2 2
MIRT324734 ACER2 alkaline ceramidase 2 4 3
MIRT386075 ZNF609 zinc finger protein 609 2 2
MIRT402060 ATP6V1F ATPase H+ transporting V1 subunit F 2 4
MIRT437422 NFKBIA NFKB inhibitor alpha 4 2
MIRT437980 TYMS thymidylate synthetase 1 1
MIRT437981 NRP2 neuropilin 2 1 1
MIRT437982 LSP1 lymphocyte-specific protein 1 1 1
MIRT439104 MYC MYC proto-oncogene, bHLH transcription factor 0 1
MIRT447143 KIF27 kinesin family member 27 2 2
MIRT447559 C14orf37 chromosome 14 open reading frame 37 2 2
MIRT449961 FMNL3 formin like 3 2 2
MIRT465087 TSPAN3 tetraspanin 3 2 2
MIRT470426 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 2
MIRT472726 MTUS1 microtubule associated scaffold protein 1 2 6
MIRT473801 MAP3K2 mitogen-activated protein kinase kinase kinase 2 2 2
MIRT474507 KLHDC8B kelch domain containing 8B 2 2
MIRT474917 KCTD21 potassium channel tetramerization domain containing 21 2 2
MIRT486549 DCTN4 dynactin subunit 4 2 2
MIRT492430 RGL2 ral guanine nucleotide dissociation stimulator like 2 2 2
MIRT493925 FAM127B retrotransposon Gag like 8A 2 4
MIRT500972 SPTSSA serine palmitoyltransferase small subunit A 2 2
MIRT501431 RAB11FIP4 RAB11 family interacting protein 4 2 2
MIRT502410 GATA6 GATA binding protein 6 2 8
MIRT506368 NUP155 nucleoporin 155 2 6
MIRT507497 E2F7 E2F transcription factor 7 2 6
MIRT520041 YOD1 YOD1 deubiquitinase 2 6
MIRT522366 NAP1L1 nucleosome assembly protein 1 like 1 2 4
MIRT531281 SLC7A7 solute carrier family 7 member 7 2 2
MIRT543674 FAM135A family with sequence similarity 135 member A 2 2
MIRT545199 HIST1H2BD histone cluster 1 H2B family member d 2 2
MIRT546336 TGFBR3 transforming growth factor beta receptor 3 2 2
MIRT546452 SLC9A7 solute carrier family 9 member A7 2 2
MIRT546787 RCC2 regulator of chromosome condensation 2 2 4
MIRT547253 NXPE3 neurexophilin and PC-esterase domain family member 3 2 2
MIRT547454 MBD4 methyl-CpG binding domain 4, DNA glycosylase 2 2
MIRT547581 LRIG3 leucine rich repeats and immunoglobulin like domains 3 2 4
MIRT547902 HOXA9 homeobox A9 2 4
MIRT549503 ABHD2 abhydrolase domain containing 2 2 2
MIRT549583 ZNF850 zinc finger protein 850 2 2
MIRT551888 MMS22L MMS22 like, DNA repair protein 2 2
MIRT552125 MED10 mediator complex subunit 10 2 2
MIRT554188 SLC35E2B solute carrier family 35 member E2B 2 2
MIRT555552 PLEKHA3 pleckstrin homology domain containing A3 2 2
MIRT556285 MAPK1 mitogen-activated protein kinase 1 2 2
MIRT556980 HSPA4L heat shock protein family A (Hsp70) member 4 like 2 2
MIRT559183 BRAP BRCA1 associated protein 2 2
MIRT561215 ZSWIM1 zinc finger SWIM-type containing 1 2 2
MIRT562352 EXOC8 exocyst complex component 8 2 2
MIRT565603 SLC35G1 solute carrier family 35 member G1 2 2
MIRT575599 Gnl1 guanine nucleotide binding protein-like 1 2 3
MIRT610363 GNL1 G protein nucleolar 1 (putative) 2 3
MIRT617860 FMO4 flavin containing monooxygenase 4 2 2
MIRT698193 TMEM66 store-operated calcium entry associated regulatory factor 1 1
MIRT704411 CTPS1 CTP synthase 1 2 2
MIRT732864 NARS asparaginyl-tRNA synthetase 3 0
MIRT732867 AJAP1 adherens junctions associated protein 1 3 0
MIRT732868 COL24A1 collagen type XXIV alpha 1 chain 3 0
MIRT735738 RASSF4 Ras association domain family member 4 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-196a Curcumin NULL 969516 Microarray BxPC-3 human pancreatic carcinoma cell line 18347134 2008 down-regulated
miR-196a Diethylstilbestrol approved 448537 Microarray mammosphere-derived epithelial cells (MDEC) 19549897 2009 down-regulated
miR-196a Polylysine NULL 162282 Quantitative real-time PCR 293T(FLAG AGO2) cells 20529860 2010 down-regulated
miR-196a Trypaflavine NULL NULL Quantitative real-time PCR 293T(FLAG AGO2) cells 20529860 2010 down-regulated
miR-196a Arsenic trioxide approved 14888 Quantitative real-time PCR acute promyelocytic leukemia 22072212 2012 up-regulated
miR-196a 1,2,6-Tri-O-galloyl-beta-D-glucopyranose NULL NULL Microarray HepG2 hepatocarcinoma cells. 22506400 2011 down-regulated
miR-196a Curcumin NULL 969516 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-196a Narangin NULL 442428 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-196a Proanthocyanin NULL 108065 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-196a (S)-3,5-dihydroxyphenylglycine (DHPG) NULL 443586 Quantitative real-time PCR mouse brain 22309833 2012 up-regulated
miR-196a (S)-3,5-dihydroxyphenylglycine (DHPG) NULL 443586 Quantitative real-time PCR mouse brain 22309833 2012 up-regulated
miR-196a 17beta-estradiol (E2) approved 5757 Microarray rat breast 17700064 2007 down-regulated
miR-196a (S)-3,5-dihydroxyphenylglycine (DHPG) NULL 443586 Quantitative real-time PCR mouse brain 22309833 2012 up-regulated
miR-196a Galactose NULL 6036 Quantitative real-time PCR lens 22736950 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-196a-5p (e)-2-methyl-1-[2-(2-methyl-1h-indol-3-yl)indolin-1-yl]but-2-en-1-one 5388204 NSC633484 resistant
hsa-miR-196a-5p (E)-3-[2-(4-methoxyphenyl)imidazo[1,2-a]pyridin-3-yl]-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one 54613570 NSC750335 sensitive
hsa-miR-196a-5p 1-[4-(5,6-diphenyl-1,2,4-triazin-3-yl)piperazin-1-yl]-2-[4-(4-methoxyphenyl)piperazin-1-yl]ethanone 54612996 NSC749161 sensitive
hsa-miR-196a-5p 2-[(e)-[6-(4-chloro-3-nitrophenyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl]methylideneamino]guanidine;hydrochloride 16099315 NSC728901 resistant
hsa-miR-196a-5p 2-amino-6-(benzylamino)-4-(2-chlorophenyl)pyridine-3,5-dicarbonitrile 24205132 NSC734396 resistant
hsa-miR-196a-5p 7-[(3,4-dimethoxyphenyl)methyl]-6-phenyl-4,5-dihydropyrrolo[3,4-g][1,2]benzoxazole 60148271 NSC754077 sensitive
hsa-miR-196a-5p Bisarylpurine 45028308 NSC742146 resistant
hsa-miR-196a-5p Camptothecin derivative 97226 NSC107124 sensitive
hsa-miR-196a-5p Dimethylarsinothious acid, 2,4-pyrimidinediyl ester 294741 NSC163664 resistant
hsa-miR-196a-5p Ethyl 5-(2,4-dichlorobenzoyl)oxy-4-oxo-1,3-diphenyl-2-thioxo-thieno[2,3-d]pyrimidine-6-carboxylate 383097 NSC671141 resistant
hsa-miR-196a-5p Gw620972x 766949 NSC756282 sensitive
hsa-miR-196a-5p Methyl 11h-pyrido[2,3-a]carbazole-5-carboxylate 13776879 NSC740203 sensitive
hsa-miR-196a-5p Methyl 6-[2-(diethylamino)ethoxy]-7-[(E)-3-(4-methoxyphenyl)prop-2-enoyl]-3-methyl-1-benzofuran-2-carboxylate;hydrochloride 24204523 NSC732112 resistant
hsa-miR-196a-5p N'-[2-(1,3-benzoxazol-2-ylamino)-6-methylpyrimidin-4-yl]-2-hydroxybenzohydrazide 24205702 NSC736401 resistant
hsa-miR-196a-5p N-(1,3-benzothiazol-2-yl)-2-[4-[(Z)-(3-oxo-1-benzofuran-2-ylidene)methyl]phenoxy]acetamide 45028625 NSC743506 resistant
hsa-miR-196a-5p N,n'-bis[(z)-(2-hydroxyphenyl)methylideneamino]decanediamide 135408549 NSC49488 resistant
hsa-miR-196a-5p NSC617562 NSC617562 resistant
hsa-miR-196a-5p NSC756998 NSC756998 sensitive
hsa-miR-196a-5p Tellurium, trichloro[1,2-hexanedioato(2-)-o,o']-, ammonium 498945 NSC641009 resistant
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (SKOV3, 2008, OVCAR10, OVCAR3, HeLa, MCF7, MDA-MB-468)
hsa-miR-196a-5p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-196a-5p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-196a-5p Sorafenib 216239 NSC747971 approved resistant High Hepatocellular Carcinoma cell line (HepG2, Hep-394, Hep-SWX, Huh-7)
hsa-miR-196a-5p Imatinib 5291 NSC743414 approved resistant High Myelogenous Leukemia cell line (MYL)
hsa-miR-196a-5p 10-Hydroxycamptothecin 97226 NSC107124 sensitive High Gastric Cancer cell line (BGC823, SGC-7901, MGC-803, HGC-27, NCI-N87, AGS)
hsa-miR-196a-5p Tamoxifen 2733525 NSC180973 approved sensitive High Breast Cancer cell line (MCF-7, LY2)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved sensitive High Ovarian Cancer cell line (A2780)
hsa-miR-196a-5p Fulvestrant 17756771 NSC719276 approved resistant Low Breast Cancer cell line (MCF-7)
hsa-miR-196a-5p Tamoxifen 2733525 NSC180973 approved resistant Low Breast Cancer cell line (MCF-7)
hsa-miR-196a-5p Doxorubicin 31703 NSC123127 approved resistant High Hepatocellular Carcinoma cell line (HepG2)
hsa-miR-196a-5p Docetaxel 148124 NSC628503 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-196a-5p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-196a-5p Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer cell line (RKO)
hsa-miR-196a-5p Docetaxel 148124 NSC628503 approved resistant Low Breast Cancer tissue and cell line (MCF-7)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved resistant Low Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved resistant Low Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-196a-5p Tamoxifen 2733525 NSC180973 approved sensitive Low Breast Cancer cell line (MCF-7)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-196a-5p Doxorubicin 31703 NSC123127 approved sensitive High Chronic Myelogenous Leukemia cell line (K562)
hsa-miR-196a-5p Tamoxifen 2733525 NSC180973 approved sensitive Low Breast Cancer cell line (TAMR1, TAMR4, TAMR8)
hsa-miR-196a-5p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-196a-5p Dabrafenib 44462760 NSC764134 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-196a-5p Cytoxan + Doxorubicin + Fluorouracil resistant High Breast Cancer tissue
hsa-miR-196a-5p Cytoxan + Epirubicin + Fluorouracil resistant High Breast Cancer tissue
hsa-miR-196a-5p Cytoxan + Pirarubicin + Fluorouracil resistant High Breast Cancer tissue
hsa-miR-196a-5p Doxorubicin + Taxol resistant High Breast Cancer tissue
hsa-miR-196a-5p Ceritinib 57379345 NSC776422 approved sensitive High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-196a-5p Gefitinib 123631 NSC715055 approved resistant High Non-Small Cell Lung Cancer cell line (PC-9)
hsa-miR-196a-5p Yuanhuadine 6440572 resistant High Non-Small Cell Lung Cancer cell line (PC-9)
hsa-miR-196a-5p Paclitaxel 36314 NSC125973 approved sensitive Low Prostate Cancer cell line (DU-145R)
hsa-miR-196a-5p Paclitaxel + Cisplatin sensitive Low Esophageal Squamous Cell Carcinoma tissue
hsa-miR-196a-5p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (WM266) (2uM)
hsa-miR-196a-5p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (WM266) (1uM)
hsa-miR-196a-5p Trametinib 11707110 NSC758246 approved sensitive High Melanoma cell line (WM266) (2uM)
hsa-miR-196a-5p Trametinib 11707110 NSC758246 approved sensitive High Melanoma cell line (WM266) (1uM)
hsa-miR-196a-5p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-196a-5p Paclitaxel 36314 NSC125973 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-196a-5p Trastuzumab resistant High Breast Cancer cell line (MDA‐MB‐231, SKBR3, HEK‐293T)
hsa-miR-196a-5p Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (AsPC-1)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780CIS)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved resistant High Hypopharyngeal Cancer cell line (FaDu)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved resistant High Epithelial Ovarian Cancer cell line (SKOV3)
hsa-miR-196a-5p Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-miR-196a-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-196a-5p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-196a-5p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (CAL-27) (cytosolic RNA)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (CAL-27) (total RNA)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-196a-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-196a-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM17)
hsa-miR-196a-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM16)
hsa-miR-196a-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (BAS)
hsa-miR-196a-5p Doxorubicin 31703 NSC123127 approved sensitive cell line (BAS)
hsa-miR-196a-5p Tamoxifen 2733525 NSC180973 approved resistant cell line (LCC2)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-miR-196a-5p Testosterone+Exemestane sensitive cell line (MCF-7)
hsa-miR-196a-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-196a-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (MGC-803)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (RPMI2650)
hsa-miR-196a-5p Paclitaxel 36314 NSC125973 approved resistant cell line (SKOV3)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-196a-5p Tamoxifen 2733525 NSC180973 approved sensitive cell line (TamR8)
hsa-miR-196a-5p Tamoxifen 2733525 NSC180973 approved sensitive cell line (TamR1)
hsa-miR-196a-5p Oxaliplatin 6857599 NSC266046 approved resistant cell line (IGROV-1)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved resistant cell line (IGROV-1)
hsa-miR-196a-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (PC3PR70)
hsa-miR-196a-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (PC3PR200)
hsa-miR-196a-5p Neoadjuvant chemotherapy resistant tissue (breast cancer)
hsa-miR-196a-5p Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR3)
hsa-miR-196a-5p Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)
hsa-miR-196a-5p Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (H460)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved resistant cell line (OVCAR3)
hsa-miR-196a-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (TOV-112D)

Error report submission