miRTarBase - #MIRT027940


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pre-miRNA Information
pre-miRNA hsa-mir-93   
Genomic Coordinates chr7: 100093768 - 100093847
Synonyms MIRN9, MIRN93, hsa-mir-93, miR-93, MIR93
Description Homo sapiens miR-93 stem-loop
Comment Mourelatos et al. identified two copies of this sequence mapping to chromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 . The 5' end of the miRNA may be offset with respect to previous annotations.
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-93-5p
Sequence 11| CAAAGUGCUGUUCGUGCAGGUAG |33
Evidence Experimental
Experiments Cloned
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN1084532 13 COSMIC
COSN30193114 13 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1328828703 6 dbSNP
rs751048634 9 dbSNP
rs1286608125 10 dbSNP
rs779705683 13 dbSNP
rs761414978 14 dbSNP
rs1284084666 17 dbSNP
rs750790187 18 dbSNP
rs765578346 20 dbSNP
rs753843516 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Biomarker Information
Biomarker ID Name Type Discovered From Mode Level Source Testing Methods
BRE8T5 miR-93 Predictive Biomarker (PRD) Clinical/Experimental Data Expression Decrease Tumor tissue Quantitative real-time PCR
BH2WX1 miR-93-5p Safety Biomarker (SAF) Clinical/Experimental Data Expression Increase Urine Real-time polymerase chain reaction
Gene Information
Gene Symbol LDLR   
Synonyms FH, FHC, LDLCQ2
Description low density lipoprotein receptor
Transcript NM_000527   
Expression
Putative miRNA Targets on LDLR
3'UTR of LDLR
(miRNA target sites are highlighted)		 
>LDLR|NM_000527|3'UTR
   1 ACATCTGCCTGGAGTCCCGTCCCTGCCCAGAACCCTTCCTGAGACCTCGCCGGCCTTGTTTTATTCAAAGACAGAGAAGA
  81 CCAAAGCATTGCCTGCCAGAGCTTTGTTTTATATATTTATTCATCTGGGAGGCAGAACAGGCTTCGGACAGTGCCCATGC
 161 AATGGCTTGGGTTGGGATTTTGGTTTCTTCCTTTCCTCGTGAAGGATAAGAGAAACAGGCCCGGGGGGACCAGGATGACA
 241 CCTCCATTTCTCTCCAGGAAGTTTTGAGTTTCTCTCCACCGTGACACAATCCTCAAACATGGAAGATGAAAGGGGAGGGG
 321 ATGTCAGGCCCAGAGAAGCAAGTGGCTTTCAACACACAACAGCAGATGGCACCAACGGGACCCCCTGGCCCTGCCTCATC
 401 CACCAATCTCTAAGCCAAACCCCTAAACTCAGGAGTCAACGTGTTTACCTCTTCTATGCAAGCCTTGCTAGACAGCCAGG
 481 TTAGCCTTTGCCCTGTCACCCCCGAATCATGACCCACCCAGTGTCTTTCGAGGTGGGTTTGTACCTTCCTTAAGCCAGGA
 561 AAGGGATTCATGGCGTCGGAAATGATCTGGCTGAATCCGTGGTGGCACCGAGACCAAACTCATTCACCAAATGATGCCAC
 641 TTCCCAGAGGCAGAGCCTGAGTCACTGGTCACCCTTAATATTTATTAAGTGCCTGAGACACCCGGTTACCTTGGCCGTGA
 721 GGACACGTGGCCTGCACCCAGGTGTGGCTGTCAGGACACCAGCCTGGTGCCCATCCTCCCGACCCCTACCCACTTCCATT
 801 CCCGTGGTCTCCTTGCACTTTCTCAGTTCAGAGTTGTACACTGTGTACATTTGGCATTTGTGTTATTATTTTGCACTGTT
 881 TTCTGTCGTGTGTGTTGGGATGGGATCCCAGGCCAGGGAAAGCCCGTGTCAATGAATGCCGGGGACAGAGAGGGGCAGGT
 961 TGACCGGGACTTCAAAGCCGTGATCGTGAATATCGAGAACTGCCATTGTCGTCTTTATGTCCGCCCACCTAGTGCTTCCA
1041 CTTCTATGCAAATGCCTCCAAGCCATTCACTTCCCCAATCTTGTCGTTGATGGGTATGTGTTTAAAACATGCACGGTGAG
1121 GCCGGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCATGAGGTCAGGAGATCGAG
1201 ACCATCCTGGCTAACACGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGCGGGCACCTGTAG
1281 TCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGTGTGAACCCGGGAAGCGGAGCTTGCAGTGAGCCGAGATTGCGCCA
1361 CTGCAGTCCGCAGTCTGGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAACAAAAAAAAACCATGCATGGTG
1441 CATCAGCAGCCCATGGCCTCTGGCCAGGCATGGCGAGGCTGAGGTGGGAGGATGGTTTGAGCTCAGGCATTTGAGGCTGT
1521 CGTGAGCTATGATTATGCCACTGCTTTCCAGCCTGGGCAACATAGTAAGACCCCATCTCTTAAAAAATGAATTTGGCCAG
1601 ACACAGGTGCCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGCTGGATCACTTGAGTTCAGGAGTTGGAGACCAGG
1681 CCTGAGCAACAAAGCGAGATCCCATCTCTACAAAAACCAAAAAGTTAAAAATCAGCTGGGTACGGTGGCACGTGCCTGTG
1761 ATCCCAGCTACTTGGGAGGCTGAGGCAGGAGGATCGCCTGAGCCCAGGAGGTGGAGGTTGCAGTGAGCCATGATCGAGCC
1841 ACTGCACTCCAGCCTGGGCAACAGATGAAGACCCTATTTCAGAAATACAACTATAAAAAAATAAATAAATCCTCCAGTCT
1921 GGATCGTTTGACGGGACTTCAGGTTCTTTCTGAAATCGCCGTGTTACTGTTGCACTGATGTCCGGAGAGACAGTGACAGC
2001 CTCCGTCAGACTCCCGCGTGAAGATGTCACAAGGGATTGGCAATTGTCCCCAGGGACAAAACACTGTGTCCCCCCCAGTG
2081 CAGGGAACCGTGATAAGCCTTTCTGGTTTCGGAGCACGTAAATGCGTCCCTGTACAGATAGTGGGGATTTTTTGTTATGT
2161 TTGCACTTTGTATATTGGTTGAAACTGTTATCACTTATATATATATATATACACACATATATATAAAATCTATTTATTTT
2241 TGCAAACCCTGGTTGCTGTATTTGTTCAGTGACTATTCTCGGGGCCCTGTGTAGGGGGTTATTGCCTCTGAAATGCCTCT
2321 TCTTTATGTACAAAGATTATTTGCACGAACTGGACTGTGTGCAACGCTTTTTGGGAGAATGATGTCCCCGTTGTATGTAT
2401 GAGTGGCTTCTGGGAGATGGGTGTCACTTTTTAAACCACTGTATAGAAGGTTTTTGTAGCCTGAATGTCTTACTGTGATC
2481 AATTAAATTTCTTAAATGAACCAATTTGTCTAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gaUGGACGUGCUUGUCGUGAAAc 5'
            :||||:|    ||||||||| 
Target 5' acGCCTGTAATCCCAGCACTTTg 3'
 1138 - 1160 165.00 -24.00
2 
miRNA  3' gaUGGACGUGCUUGUCGUGAAAc 5'
            :||||:|    ||||||||| 
Target 5' acGCCTGTAATCCCAGCACTTTg 3'
 1614 - 1636 165.00 -24.00
3 
miRNA  3' gauGGAC-GUGCUUGUCGUGAAAc 5'
             ::|| :|:|  : ||||||| 
Target 5' tttTTTGTTATG-TTTGCACTTTg 3'
 2148 - 2170 143.00 -13.80
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
918887 2 ClinVar
265909 14 ClinVar
630614 20 ClinVar
251226 44 ClinVar
265910 53 ClinVar
328056 142 ClinVar
328057 170 ClinVar
889308 224 ClinVar
889309 288 ClinVar
328058 316 ClinVar
328059 339 ClinVar
328060 373 ClinVar
328061 377 ClinVar
328062 421 ClinVar
328063 504 ClinVar
328064 505 ClinVar
889991 518 ClinVar
328065 524 ClinVar
889992 534 ClinVar
328066 564 ClinVar
328067 580 ClinVar
328068 585 ClinVar
328069 654 ClinVar
328070 667 ClinVar
891550 705 ClinVar
891551 717 ClinVar
328071 768 ClinVar
328072 774 ClinVar
328073 785 ClinVar
684566 804 ClinVar
328074 805 ClinVar
328075 809 ClinVar
891809 850 ClinVar
328076 855 ClinVar
328077 943 ClinVar
328078 947 ClinVar
891810 966 ClinVar
891811 967 ClinVar
328079 980 ClinVar
328080 983 ClinVar
328081 995 ClinVar
891812 996 ClinVar
889364 1041 ClinVar
889365 1131 ClinVar
328082 1132 ClinVar
328083 1134 ClinVar
328084 1141 ClinVar
328085 1154 ClinVar
889366 1168 ClinVar
328086 1169 ClinVar
890058 1174 ClinVar
328087 1216 ClinVar
328088 1218 ClinVar
890059 1228 ClinVar
328089 1232 ClinVar
328090 1257 ClinVar
328091 1263 ClinVar
328092 1269 ClinVar
890060 1270 ClinVar
328093 1293 ClinVar
328094 1333 ClinVar
328095 1337 ClinVar
328096 1341 ClinVar
328097 1355 ClinVar
328098 1357 ClinVar
891604 1370 ClinVar
328099 1377 ClinVar
891605 1378 ClinVar
891606 1394 ClinVar
891873 1418 ClinVar
328100 1420 ClinVar
328101 1431 ClinVar
891874 1431 ClinVar
328102 1454 ClinVar
328103 1511 ClinVar
891875 1551 ClinVar
891876 1559 ClinVar
889426 1562 ClinVar
328104 1601 ClinVar
328105 1610 ClinVar
328106 1744 ClinVar
889427 1745 ClinVar
328107 1753 ClinVar
328108 1763 ClinVar
328109 1794 ClinVar
328110 1832 ClinVar
328111 1859 ClinVar
328112 1896 ClinVar
328113 1917 ClinVar
328114 1918 ClinVar
328115 1932 ClinVar
328116 1961 ClinVar
890101 1962 ClinVar
890102 2005 ClinVar
328117 2017 ClinVar
328118 2055 ClinVar
328119 2070 ClinVar
890103 2112 ClinVar
890104 2127 ClinVar
890105 2133 ClinVar
328120 2174 ClinVar
328121 2196 ClinVar
328122 2196 ClinVar
328123 2209 ClinVar
328124 2211 ClinVar
890680 2211 ClinVar
328125 2252 ClinVar
890681 2283 ClinVar
328126 2320 ClinVar
890682 2351 ClinVar
328127 2366 ClinVar
328128 2367 ClinVar
328129 2385 ClinVar
COSN21051196 12 COSMIC
COSN31975863 36 COSMIC
COSN15304446 53 COSMIC
COSN22375529 64 COSMIC
COSN31599944 87 COSMIC
COSN30524511 114 COSMIC
COSN13779131 115 COSMIC
COSN31561204 126 COSMIC
COSN15634489 142 COSMIC
COSN26569551 146 COSMIC
COSN30137765 200 COSMIC
COSN28725835 316 COSMIC
COSN24572525 445 COSMIC
COSN28658844 667 COSMIC
COSN17037621 763 COSMIC
COSN28673675 774 COSMIC
rs2738464 316 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs773170427 3 dbSNP
rs762784474 4 dbSNP
rs72658871 14 dbSNP
rs371804196 19 dbSNP
rs56270417 20 dbSNP
rs545437018 21 dbSNP
rs766917684 24 dbSNP
rs1234931640 25 dbSNP
rs1185819720 26 dbSNP
rs72658872 29 dbSNP
rs1461282475 34 dbSNP
rs763725187 37 dbSNP
rs966455007 41 dbSNP
rs879254527 44 dbSNP
rs1205723861 47 dbSNP
rs1408117816 49 dbSNP
rs17243004 50 dbSNP
rs755797548 52 dbSNP
rs14158 53 dbSNP
rs746245206 58 dbSNP
rs1315160655 67 dbSNP
rs1398411835 67 dbSNP
rs374945549 69 dbSNP
rs773717642 69 dbSNP
rs758695681 75 dbSNP
rs1414365663 77 dbSNP
rs1280314446 80 dbSNP
rs761573909 81 dbSNP
rs780676892 82 dbSNP
rs747457496 83 dbSNP
rs1243420096 87 dbSNP
rs768828593 89 dbSNP
rs776540572 96 dbSNP
rs748196009 102 dbSNP
rs1039733927 103 dbSNP
rs770159026 113 dbSNP
rs1233039967 115 dbSNP
rs1317252841 119 dbSNP
rs1470882424 129 dbSNP
rs1400966015 131 dbSNP
rs553019832 132 dbSNP
rs773506427 136 dbSNP
rs762842582 141 dbSNP
rs3826810 142 dbSNP
rs774399171 144 dbSNP
rs1374060162 146 dbSNP
rs1434433343 147 dbSNP
rs1038174435 151 dbSNP
rs759363483 153 dbSNP
rs767452364 154 dbSNP
rs1279013982 155 dbSNP
rs1376124751 156 dbSNP
rs1355613354 158 dbSNP
rs1234969609 160 dbSNP
rs1209880267 163 dbSNP
rs1270449809 167 dbSNP
rs1448966538 168 dbSNP
rs886054157 170 dbSNP
rs1305478751 171 dbSNP
rs1287907174 183 dbSNP
rs1487074534 184 dbSNP
rs1047249425 189 dbSNP
rs1345490895 192 dbSNP
rs34890611 192 dbSNP
rs752228709 199 dbSNP
rs529666063 200 dbSNP
rs918630095 202 dbSNP
rs1269103318 205 dbSNP
rs1201882697 207 dbSNP
rs1236996978 208 dbSNP
rs1037491334 211 dbSNP
rs898918795 213 dbSNP
rs755564723 215 dbSNP
rs56263043 218 dbSNP
rs763742059 219 dbSNP
rs775160734 220 dbSNP
rs970591604 222 dbSNP
rs1165817060 223 dbSNP
rs1448226030 223 dbSNP
rs17243011 224 dbSNP
rs758854149 226 dbSNP
rs780257440 229 dbSNP
rs1443125642 231 dbSNP
rs1476427860 240 dbSNP
rs1327851898 242 dbSNP
rs1245265296 243 dbSNP
rs1368694352 245 dbSNP
rs1232340672 246 dbSNP
rs1030770956 247 dbSNP
rs956603752 262 dbSNP
rs1341083516 265 dbSNP
rs1045679023 269 dbSNP
rs568538528 278 dbSNP
rs1468549333 281 dbSNP
rs72658873 282 dbSNP
rs907221420 288 dbSNP
rs1001791219 290 dbSNP
rs1363424890 290 dbSNP
rs1194396386 295 dbSNP
rs1244226939 300 dbSNP
rs1056485811 301 dbSNP
rs1170258709 302 dbSNP
rs1418768334 308 dbSNP
rs1463144392 311 dbSNP
rs781686110 312 dbSNP
rs748248927 313 dbSNP
rs1367545960 314 dbSNP
rs2738464 316 dbSNP
rs1318840516 320 dbSNP
rs773631029 321 dbSNP
rs532336880 324 dbSNP
rs749503077 325 dbSNP
rs1277184654 326 dbSNP
rs1335068442 330 dbSNP
rs1234654805 335 dbSNP
rs1270698036 336 dbSNP
rs17249029 339 dbSNP
rs1206263668 342 dbSNP
rs1481350603 360 dbSNP
rs539448338 361 dbSNP
rs1198738911 367 dbSNP
rs886054158 373 dbSNP
rs1480900329 376 dbSNP
rs35740761 377 dbSNP
rs886054159 377 dbSNP
rs941506263 378 dbSNP
rs13306508 379 dbSNP
rs1029310311 380 dbSNP
rs1479533551 381 dbSNP
rs551455738 383 dbSNP
rs1038947613 388 dbSNP
rs955252041 391 dbSNP
rs1309141874 394 dbSNP
rs1398543830 402 dbSNP
rs1222312035 404 dbSNP
rs1297925918 407 dbSNP
rs1323809323 408 dbSNP
rs111252880 409 dbSNP
rs1225935211 412 dbSNP
rs746014399 421 dbSNP
rs1343748559 426 dbSNP
rs768511996 428 dbSNP
rs962660703 442 dbSNP
rs1470307344 448 dbSNP
rs1431806571 450 dbSNP
rs1030950454 453 dbSNP
rs892384466 456 dbSNP
rs563455497 457 dbSNP
rs566969425 458 dbSNP
rs1010699612 460 dbSNP
rs779622318 470 dbSNP
rs534018759 480 dbSNP
rs13306509 493 dbSNP
rs553181858 502 dbSNP
rs574677226 504 dbSNP
rs2738465 505 dbSNP
rs928645831 515 dbSNP
rs1202555241 517 dbSNP
rs115882455 518 dbSNP
rs1055802884 520 dbSNP
rs886054160 524 dbSNP
rs893357780 530 dbSNP
rs1315922139 531 dbSNP
rs771870462 534 dbSNP
rs1041897795 549 dbSNP
rs1336646731 559 dbSNP
rs1453547662 560 dbSNP
rs886054161 564 dbSNP
rs1197269237 572 dbSNP
rs1376985414 575 dbSNP
rs903377930 576 dbSNP
rs1453346985 577 dbSNP
rs1159146958 578 dbSNP
rs1410473697 579 dbSNP
rs886054162 580 dbSNP
rs144675877 583 dbSNP
rs772754135 585 dbSNP
rs1182885176 586 dbSNP
rs1029858553 597 dbSNP
rs1257702922 598 dbSNP
rs1202805603 599 dbSNP
rs1366656009 600 dbSNP
rs955157314 611 dbSNP
rs545799953 615 dbSNP
rs760162975 625 dbSNP
rs916096453 628 dbSNP
rs947785651 642 dbSNP
rs1247384446 650 dbSNP
rs1044829543 651 dbSNP
rs906199137 652 dbSNP
rs563911564 654 dbSNP
rs1386029294 655 dbSNP
rs1290839082 656 dbSNP
rs1421335501 657 dbSNP
rs1017957205 659 dbSNP
rs1162658526 665 dbSNP
rs1052533174 666 dbSNP
rs1433099 667 dbSNP
rs1427406786 668 dbSNP
rs1011252578 669 dbSNP
rs1022115298 673 dbSNP
rs1489696395 681 dbSNP
rs1291532174 682 dbSNP
rs1350835746 687 dbSNP
rs899706512 696 dbSNP
rs973989333 703 dbSNP
rs1250120157 704 dbSNP
rs918417347 705 dbSNP
rs1292043796 708 dbSNP
rs548236850 710 dbSNP
rs1298047082 711 dbSNP
rs1361400627 714 dbSNP
rs951251390 717 dbSNP
rs17243018 718 dbSNP
rs1424991969 721 dbSNP
rs1392879289 726 dbSNP
rs928671935 727 dbSNP
rs568219285 728 dbSNP
rs561985820 733 dbSNP
rs1373122365 734 dbSNP
rs1172132110 736 dbSNP
rs955445720 737 dbSNP
rs991871021 742 dbSNP
rs1016026241 743 dbSNP
rs1453669343 746 dbSNP
rs1249094145 748 dbSNP
rs886054163 768 dbSNP
rs2738466 774 dbSNP
rs1340632616 776 dbSNP
rs947603051 778 dbSNP
rs1042028681 779 dbSNP
rs903341912 781 dbSNP
rs1221704622 782 dbSNP
rs886054164 785 dbSNP
rs17242677 804 dbSNP
rs886054165 805 dbSNP
rs1405394420 807 dbSNP
rs562862170 809 dbSNP
rs981581812 810 dbSNP
rs1390769729 814 dbSNP
rs1051939027 817 dbSNP
rs927677108 818 dbSNP
rs939122382 823 dbSNP
rs890845080 831 dbSNP
rs1006653969 838 dbSNP
rs533410799 849 dbSNP
rs1052078773 850 dbSNP
rs886054166 855 dbSNP
rs913587655 863 dbSNP
rs1362450495 872 dbSNP
rs946652321 873 dbSNP
rs1018344856 876 dbSNP
rs1374100901 879 dbSNP
rs551784908 883 dbSNP
rs1240502680 887 dbSNP
rs1201927366 888 dbSNP
rs180925667 888 dbSNP
rs534345019 889 dbSNP
rs898190149 893 dbSNP
rs1264042483 905 dbSNP
rs17243025 908 dbSNP
rs567716996 926 dbSNP
rs142953361 927 dbSNP
rs1242375210 938 dbSNP
rs375768277 941 dbSNP
rs981660023 942 dbSNP
rs886054167 943 dbSNP
rs886054168 947 dbSNP
rs370513353 950 dbSNP
rs1449889866 964 dbSNP
rs72658874 966 dbSNP
rs991614293 967 dbSNP
rs368246278 974 dbSNP
rs1004735700 978 dbSNP
rs575645180 979 dbSNP
rs886054169 980 dbSNP
rs539332003 981 dbSNP
rs10409044 983 dbSNP
rs1023137968 986 dbSNP
rs572739101 987 dbSNP
rs189408873 995 dbSNP
rs933578781 998 dbSNP
rs1185663904 1008 dbSNP
rs1368295902 1009 dbSNP
rs561450427 1011 dbSNP
rs928820502 1012 dbSNP
rs1170205444 1023 dbSNP
rs1284296102 1024 dbSNP
rs1398665908 1025 dbSNP
rs1449503624 1027 dbSNP
rs1343143553 1033 dbSNP
rs1317183739 1039 dbSNP
rs1052334287 1041 dbSNP
rs763543379 1043 dbSNP
rs1362812284 1044 dbSNP
rs1464653117 1044 dbSNP
rs889318331 1045 dbSNP
rs960474259 1048 dbSNP
rs574545882 1050 dbSNP
rs1183737046 1056 dbSNP
rs1474459609 1066 dbSNP
rs1241792592 1073 dbSNP
rs1336766327 1075 dbSNP
rs544415188 1076 dbSNP
rs1039489968 1085 dbSNP
rs898258959 1086 dbSNP
rs562725399 1087 dbSNP
rs1290505061 1092 dbSNP
rs1229597170 1093 dbSNP
rs995096461 1095 dbSNP
rs1269271919 1096 dbSNP
rs921160736 1098 dbSNP
rs1341937133 1099 dbSNP
rs932571387 1110 dbSNP
rs1050904721 1111 dbSNP
rs796779445 1113 dbSNP
rs886999810 1115 dbSNP
rs1002822403 1116 dbSNP
rs1229266309 1120 dbSNP
rs1035917105 1124 dbSNP
rs868141515 1125 dbSNP
rs533706213 1128 dbSNP
rs1266961929 1129 dbSNP
rs958607333 1131 dbSNP
rs886054170 1132 dbSNP
rs181377148 1134 dbSNP
rs1247272425 1138 dbSNP
rs1021681712 1140 dbSNP
rs367606490 1141 dbSNP
rs1271708936 1146 dbSNP
rs1305653539 1146 dbSNP
rs886054171 1154 dbSNP
rs1218652926 1157 dbSNP
rs1484260163 1159 dbSNP
rs1199016973 1168 dbSNP
rs17242683 1169 dbSNP
rs1404776098 1173 dbSNP
rs17249379 1174 dbSNP
rs567778029 1183 dbSNP
rs955115279 1184 dbSNP
rs1354401903 1185 dbSNP
rs987763356 1195 dbSNP
rs910707801 1198 dbSNP
rs1477750488 1199 dbSNP
rs1177757604 1203 dbSNP
rs531825277 1204 dbSNP
rs1467247139 1213 dbSNP
rs1430841283 1216 dbSNP
rs34113544 1216 dbSNP
rs376570456 1217 dbSNP
rs3180023 1218 dbSNP
rs1192662925 1219 dbSNP
rs1037555185 1224 dbSNP
rs1301913379 1226 dbSNP
rs1198787723 1227 dbSNP
rs72658875 1228 dbSNP
rs557775030 1229 dbSNP
rs1316099627 1232 dbSNP
rs398059563 1232 dbSNP
rs1303877188 1233 dbSNP
rs1339575612 1235 dbSNP
rs995872272 1236 dbSNP
rs1224095106 1239 dbSNP
rs1022938465 1244 dbSNP
rs1285113710 1250 dbSNP
rs886054172 1257 dbSNP
rs943516725 1258 dbSNP
rs1038278493 1259 dbSNP
rs566711349 1261 dbSNP
rs919654490 1262 dbSNP
rs2915966 1263 dbSNP
rs1261540922 1267 dbSNP
rs2978615 1269 dbSNP
rs573433655 1270 dbSNP
rs1271612690 1274 dbSNP
rs1199328383 1278 dbSNP
rs1257389541 1281 dbSNP
rs1214169810 1282 dbSNP
rs1316676978 1285 dbSNP
rs543880088 1288 dbSNP
rs886800436 1290 dbSNP
rs556381931 1293 dbSNP
rs1314481375 1294 dbSNP
rs1396613898 1299 dbSNP
rs1057085416 1303 dbSNP
rs1381691007 1304 dbSNP
rs1287310026 1305 dbSNP
rs1364042003 1317 dbSNP
rs1003108334 1318 dbSNP
rs1158969365 1320 dbSNP
rs1035802302 1325 dbSNP
rs72658876 1326 dbSNP
rs1186305784 1327 dbSNP
rs1423879019 1332 dbSNP
rs10415069 1333 dbSNP
rs1184378973 1335 dbSNP
rs72658877 1337 dbSNP
rs1219175449 1338 dbSNP
rs186461273 1341 dbSNP
rs1291687824 1347 dbSNP
rs967844018 1349 dbSNP
rs1293472492 1350 dbSNP
rs998968531 1350 dbSNP
rs7258146 1355 dbSNP
rs886054173 1357 dbSNP
rs932540402 1358 dbSNP
rs986757456 1365 dbSNP
rs191796971 1370 dbSNP
rs1162567206 1371 dbSNP
rs55903358 1377 dbSNP
rs563300769 1378 dbSNP
rs13344419 1386 dbSNP
rs1477299436 1387 dbSNP
rs1263372825 1391 dbSNP
rs571673106 1394 dbSNP
rs532985164 1395 dbSNP
rs1023575735 1398 dbSNP
rs766298942 1399 dbSNP
rs931426690 1402 dbSNP
rs1191100844 1403 dbSNP
rs1250670286 1406 dbSNP
rs1249699598 1407 dbSNP
rs1280319707 1407 dbSNP
rs35921663 1407 dbSNP
rs1440999316 1408 dbSNP
rs773647470 1409 dbSNP
rs1487173855 1412 dbSNP
rs1044360829 1415 dbSNP
rs1322607812 1416 dbSNP
rs1176460493 1417 dbSNP
rs1387307471 1417 dbSNP
rs1257290698 1418 dbSNP
rs72658878 1418 dbSNP
rs1464647059 1419 dbSNP
rs751672818 1419 dbSNP
rs1035869546 1420 dbSNP
rs55971831 1420 dbSNP
rs1377444970 1421 dbSNP
rs1425068315 1424 dbSNP
rs1165191772 1429 dbSNP
rs1348068399 1430 dbSNP
rs7254521 1431 dbSNP
rs1260283970 1433 dbSNP
rs1202047501 1435 dbSNP
rs1298648664 1436 dbSNP
rs1374228174 1440 dbSNP
rs1449070328 1443 dbSNP
rs1010798824 1445 dbSNP
rs1332830912 1451 dbSNP
rs190954582 1452 dbSNP
rs1046838059 1453 dbSNP
rs5742911 1454 dbSNP
rs1332734555 1456 dbSNP
rs1467916861 1465 dbSNP
rs938324505 1475 dbSNP
rs566918949 1476 dbSNP
rs375312185 1478 dbSNP
rs1362614662 1480 dbSNP
rs1013261538 1483 dbSNP
rs1042897688 1492 dbSNP
rs1240129401 1494 dbSNP
rs1440807444 1494 dbSNP
rs1181770014 1497 dbSNP
rs953729774 1504 dbSNP
rs904379725 1507 dbSNP
rs17249057 1511 dbSNP
rs1252395608 1512 dbSNP
rs555846154 1522 dbSNP
rs1031793943 1523 dbSNP
rs890539100 1532 dbSNP
rs1008876685 1538 dbSNP
rs1310813684 1539 dbSNP
rs1018036324 1541 dbSNP
rs143587805 1551 dbSNP
rs1339564747 1558 dbSNP
rs1334375934 1559 dbSNP
rs919800171 1562 dbSNP
rs973650803 1564 dbSNP
rs1310942760 1566 dbSNP
rs931380082 1567 dbSNP
rs1420853872 1573 dbSNP
rs1181899443 1574 dbSNP
rs1382631517 1574 dbSNP
rs548005398 1591 dbSNP
rs545290692 1593 dbSNP
rs17249064 1601 dbSNP
rs1238320469 1602 dbSNP
rs950921740 1606 dbSNP
rs886054174 1610 dbSNP
rs572677883 1611 dbSNP
rs1215534822 1616 dbSNP
rs1423023118 1617 dbSNP
rs983594735 1618 dbSNP
rs938645198 1620 dbSNP
rs1354999039 1621 dbSNP
rs1402296149 1629 dbSNP
rs1284234983 1631 dbSNP
rs1057078377 1647 dbSNP
rs1337888656 1651 dbSNP
rs1297979698 1670 dbSNP
rs1400994013 1671 dbSNP
rs1329342489 1675 dbSNP
rs778802644 1677 dbSNP
rs1399615433 1678 dbSNP
rs1453704614 1679 dbSNP
rs1286176511 1690 dbSNP
rs908243897 1694 dbSNP
rs892013126 1697 dbSNP
rs1163270455 1701 dbSNP
rs938446725 1704 dbSNP
rs1022190920 1706 dbSNP
rs1165014973 1707 dbSNP
rs1228052565 1710 dbSNP
rs992476656 1717 dbSNP
rs904726533 1718 dbSNP
rs915589547 1724 dbSNP
rs1192743536 1726 dbSNP
rs1488481188 1734 dbSNP
rs2738467 1744 dbSNP
rs1028044712 1745 dbSNP
rs1289988982 1748 dbSNP
rs561307544 1752 dbSNP
rs886054175 1753 dbSNP
rs1019292134 1756 dbSNP
rs961577206 1759 dbSNP
rs550542566 1763 dbSNP
rs531745927 1765 dbSNP
rs778804960 1772 dbSNP
rs972700165 1775 dbSNP
rs1235369611 1780 dbSNP
rs1325684703 1783 dbSNP
rs758370550 1785 dbSNP
rs1053381325 1786 dbSNP
rs919751976 1788 dbSNP
rs890517388 1792 dbSNP
rs886054176 1794 dbSNP
rs1017587854 1796 dbSNP
rs900543003 1797 dbSNP
rs995044372 1799 dbSNP
rs1247210396 1807 dbSNP
rs927356968 1811 dbSNP
rs1456054976 1814 dbSNP
rs182610727 1819 dbSNP
rs565257190 1824 dbSNP
rs1423094635 1826 dbSNP
rs886054177 1832 dbSNP
rs1057438076 1833 dbSNP
rs1299647076 1836 dbSNP
rs913254371 1837 dbSNP
rs1368984999 1852 dbSNP
rs1277098211 1856 dbSNP
rs1444703766 1857 dbSNP
rs886054178 1859 dbSNP
rs1332064739 1867 dbSNP
rs532600680 1868 dbSNP
rs551318860 1871 dbSNP
rs1357578385 1875 dbSNP
rs563396169 1887 dbSNP
rs570174558 1889 dbSNP
rs560271380 1890 dbSNP
rs1425853363 1891 dbSNP
rs904783005 1895 dbSNP
rs886054179 1896 dbSNP
rs1237059160 1898 dbSNP
rs1278117731 1899 dbSNP
rs1458862093 1903 dbSNP
rs1253866443 1906 dbSNP
rs1323697038 1907 dbSNP
rs1313115828 1911 dbSNP
rs779420644 1912 dbSNP
rs993011316 1913 dbSNP
rs886054180 1917 dbSNP
rs886054181 1918 dbSNP
rs1008010866 1920 dbSNP
rs1311200900 1926 dbSNP
rs527624457 1927 dbSNP
rs1377319352 1929 dbSNP
rs886054182 1932 dbSNP
rs570806765 1933 dbSNP
rs994483607 1934 dbSNP
rs533863963 1936 dbSNP
rs952648324 1940 dbSNP
rs979875703 1944 dbSNP
rs1158781903 1947 dbSNP
rs1420326940 1950 dbSNP
rs746589232 1958 dbSNP
rs1192933878 1959 dbSNP
rs1269444345 1960 dbSNP
rs1239592308 1961 dbSNP
rs8108932 1961 dbSNP
rs567179124 1962 dbSNP
rs975244851 1969 dbSNP
rs992964572 1975 dbSNP
rs1287354272 1981 dbSNP
rs925836285 1983 dbSNP
rs934576650 1984 dbSNP
rs1052943761 1985 dbSNP
rs1423347658 1988 dbSNP
rs946032559 1996 dbSNP
rs1381545519 1997 dbSNP
rs539827046 2005 dbSNP
rs549718129 2006 dbSNP
rs1359874388 2008 dbSNP
rs944805816 2009 dbSNP
rs932236221 2012 dbSNP
rs1050571534 2013 dbSNP
rs192140687 2014 dbSNP
rs900600454 2016 dbSNP
rs72658879 2017 dbSNP
rs567174080 2018 dbSNP
rs554118355 2019 dbSNP
rs1207447487 2020 dbSNP
rs1272623393 2020 dbSNP
rs1343636010 2023 dbSNP
rs1224059331 2034 dbSNP
rs1487765025 2036 dbSNP
rs1287707182 2041 dbSNP
rs1264955085 2042 dbSNP
rs886666162 2044 dbSNP
rs1351258310 2045 dbSNP
rs746880706 2045 dbSNP
rs1216610165 2046 dbSNP
rs1215543312 2049 dbSNP
rs1298529838 2053 dbSNP
rs1035178158 2054 dbSNP
rs28398082 2055 dbSNP
rs1013998032 2058 dbSNP
rs1453203726 2064 dbSNP
rs1023103008 2065 dbSNP
rs1388402980 2065 dbSNP
rs1292505823 2066 dbSNP
rs969813182 2069 dbSNP
rs1034142504 2070 dbSNP
rs545860269 2070 dbSNP
rs886054183 2070 dbSNP
rs374512158 2071 dbSNP
rs925636763 2077 dbSNP
rs955921135 2090 dbSNP
rs1179557985 2091 dbSNP
rs1382339095 2093 dbSNP
rs148054434 2112 dbSNP
rs967887118 2118 dbSNP
rs1158375667 2119 dbSNP
rs1318800359 2126 dbSNP
rs142697277 2127 dbSNP
rs1229335392 2130 dbSNP
rs184187776 2133 dbSNP
rs1386885578 2135 dbSNP
rs769309590 2137 dbSNP
rs1322141149 2138 dbSNP
rs932204930 2139 dbSNP
rs1330061813 2141 dbSNP
rs1170061974 2148 dbSNP
rs530461625 2148 dbSNP
rs912057355 2151 dbSNP
rs1377593430 2152 dbSNP
rs1200234957 2155 dbSNP
rs1455926629 2167 dbSNP
rs886054184 2174 dbSNP
rs1178022092 2175 dbSNP
rs1458435634 2175 dbSNP
rs1311010305 2178 dbSNP
rs753826430 2186 dbSNP
rs1036956819 2190 dbSNP
rs1255156293 2195 dbSNP
rs1315525771 2195 dbSNP
rs1173461249 2196 dbSNP
rs1437128950 2196 dbSNP
rs1477178403 2196 dbSNP
rs397844005 2196 dbSNP
rs3980933 2196 dbSNP
rs368041346 2197 dbSNP
rs371525227 2198 dbSNP
rs778157541 2198 dbSNP
rs1358160675 2199 dbSNP
rs146964476 2204 dbSNP
rs930744516 2204 dbSNP
rs1440373791 2205 dbSNP
rs896873275 2207 dbSNP
rs1211257792 2209 dbSNP
rs886054185 2209 dbSNP
rs1491233508 2211 dbSNP
rs1491585127 2211 dbSNP
rs73925118 2211 dbSNP
rs886054186 2211 dbSNP
rs397762834 2212 dbSNP
rs200039283 2213 dbSNP
rs1289040389 2215 dbSNP
rs80142115 2217 dbSNP
rs17249393 2219 dbSNP
rs1359242501 2221 dbSNP
rs1057153077 2227 dbSNP
rs1034193474 2231 dbSNP
rs1410287571 2234 dbSNP
rs1161479011 2249 dbSNP
rs1178227397 2251 dbSNP
rs886054187 2252 dbSNP
rs1014068352 2259 dbSNP
rs1188466932 2268 dbSNP
rs1486509831 2271 dbSNP
rs1473971795 2279 dbSNP
rs1012789318 2281 dbSNP
rs1023821990 2282 dbSNP
rs969781959 2283 dbSNP
rs1207546191 2285 dbSNP
rs775981249 2287 dbSNP
rs1465721096 2290 dbSNP
rs763224255 2296 dbSNP
rs967477623 2297 dbSNP
rs1032675131 2308 dbSNP
rs1357936896 2309 dbSNP
rs955724167 2315 dbSNP
rs1033009907 2318 dbSNP
rs72658880 2320 dbSNP
rs986139751 2320 dbSNP
rs912109652 2321 dbSNP
rs1321749513 2323 dbSNP
rs911756108 2323 dbSNP
rs944965682 2328 dbSNP
rs1391769773 2332 dbSNP
rs1167406110 2334 dbSNP
rs574560919 2347 dbSNP
rs974955474 2348 dbSNP
rs565264863 2351 dbSNP
rs930712017 2357 dbSNP
rs1218804626 2358 dbSNP
rs886054188 2366 dbSNP
rs886054189 2367 dbSNP
rs1215203964 2376 dbSNP
rs1257831337 2376 dbSNP
rs1260123022 2381 dbSNP
rs1049175551 2382 dbSNP
rs188658294 2383 dbSNP
rs886054190 2385 dbSNP
rs1364777556 2386 dbSNP
rs907874205 2390 dbSNP
rs1436333971 2391 dbSNP
rs1371841315 2397 dbSNP
rs1327938663 2398 dbSNP
rs1464264939 2401 dbSNP
rs113240958 2406 dbSNP
rs1399829240 2408 dbSNP
rs1169553095 2412 dbSNP
rs888202896 2428 dbSNP
rs936967139 2437 dbSNP
rs1061878 2439 dbSNP
rs1198316638 2445 dbSNP
rs1257052904 2455 dbSNP
rs1444499623 2463 dbSNP
rs1253098740 2468 dbSNP
rs1477629738 2468 dbSNP
rs984075081 2474 dbSNP
rs1056470933 2476 dbSNP
rs1055408843 2478 dbSNP
rs1456222441 2480 dbSNP
rs1237177851 2483 dbSNP
rs1205728017 2487 dbSNP
rs1309661507 2488 dbSNP
rs1185822547 2493 dbSNP
rs541509311 2494 dbSNP
rs1305804047 2496 dbSNP
rs1444637007 2497 dbSNP
rs866978192 2502 dbSNP
rs1368424337 2505 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gauGGAC-GUGCUUGUCGUGAAAc 5'
             ::|| :|:|  : ||||||| 
Target 5' uuuUUUGUUAUG-UUUGCACUUU- 3'
 		2 - 23
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 3949.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gauGGAC-GUGCUUGUCGUGAAAc 5'
             ::|| :|:|  : ||||||| 
Target 5' uuuUUUGUUAUG-UUUGCACUUUg 3'
 		11 - 33
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 3949.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
Experimental Support 4 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Jiyoye
Tools used in this research TargetScan
Original Description (Extracted from the article) ... HITS-CLIP data was present in Supplenentary. RNA binding protein: AGO2. ...

- Riley KJ; Rabinowitz GS; Yario TA; Luna JM; et al., 2012, The EMBO journal.

Article - Riley KJ; Rabinowitz GS; Yario TA; Luna JM; et al.
- The EMBO journal, 2012
Epstein-Barr virus (EBV) controls gene expression to transform human B cells and maintain viral latency. High-throughput sequencing and crosslinking immunoprecipitation (HITS-CLIP) identified mRNA targets of 44 EBV and 310 human microRNAs (miRNAs) in Jijoye (Latency III) EBV-transformed B cells. While 25% of total cellular miRNAs are viral, only three viral mRNAs, all latent transcripts, are targeted. Thus, miRNAs do not control the latent/lytic switch by targeting EBV lytic genes. Unexpectedly, 90% of the 1664 human 3'-untranslated regions targeted by the 12 most abundant EBV miRNAs are also targeted by human miRNAs via distinct binding sites. Half of these are targets of the oncogenic miR-17 approximately 92 miRNA cluster and associated families, including mRNAs that regulate transcription, apoptosis, Wnt signalling, and the cell cycle. Reporter assays confirmed the functionality of several EBV and miR-17 family miRNA-binding sites in EBV latent membrane protein 1 (LMP1), EBV BHRF1, and host CAPRIN2 mRNAs. Our extensive list of EBV and human miRNA targets implicates miRNAs in the control of EBV latency and illuminates viral miRNA function in general.
LinkOut: [PMID: 22473208]
Experimental Support 5 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462573. RNA binding protein: AGO2. Condition:TZM-bl BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000558518.1 | 3UTR | AUUUUUUGUUAUGUUUGCACUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000558518.1 | 3UTR | AUAGUGGGGAUUUUUUGUUAUGUUUGCACUUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000558518.1 | 3UTR | UGGGGAUUUUUUGUUAUGUUUGCACUUUGUA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM1462573
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl BaL
Location of target site ENST00000558518.1 | 3UTR | UGGUCUCCUUGCACUUUCUCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE21032 Prostate cancer -0.315 1.9e-3 -0.296 3.3e-3 83 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.512 4.4e-3 0.518 4.0e-3 25 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.747 1.0e-2 0.600 4.4e-2 9 Click to see details
GSE42095 Differentiated embryonic stem cells -0.477 1.1e-2 -0.276 1.0e-1 23 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis -0.425 3.1e-2 -0.630 1.5e-3 20 Click to see details
GSE17498 Multiple myeloma -0.221 8.5e-2 -0.186 1.3e-1 40 Click to see details
GSE38226 Liver fibrosis -0.29 1.0e-1 -0.460 1.8e-2 21 Click to see details
GSE35602 Colorectal cancer stromal tissue 0.256 1.1e-1 0.305 6.9e-2 25 Click to see details
GSE14794 Lymphoblastoid cells 0.128 1.1e-1 0.051 3.2e-1 90 Click to see details
GSE19783 ER- ER- breast cancer 0.132 1.2e-1 0.193 4.4e-2 79 Click to see details
GSE19536 Breast cancer 0.115 1.3e-1 0.156 6.1e-2 100 Click to see details
GSE26953 Aortic valvular endothelial cells -0.222 1.5e-1 -0.273 9.8e-2 24 Click to see details
GSE27834 Pluripotent stem cells 0.277 1.5e-1 0.209 2.2e-1 16 Click to see details
GSE28260 Renal cortex and medulla 0.292 1.7e-1 0.440 6.6e-2 13 Click to see details
GSE28544 Breast cancer 0.196 1.8e-1 -0.014 4.7e-1 24 Click to see details
GSE19350 CNS germ cell tumors -0.261 2.1e-1 0.000 5.0e-1 12 Click to see details
GSE32688 Pancreatic cancer -0.049 3.9e-1 0.062 3.7e-1 32 Click to see details
GSE21687 Ependynoma primary tumors 0.029 4.1e-1 -0.046 3.6e-1 64 Click to see details
GSE19783 ER+ ER+ breast cancer 0.015 4.7e-1 0.226 1.7e-1 20 Click to see details
GSE17306 Multiple myeloma 0.003 4.9e-1 -0.004 4.9e-1 49 Click to see details
GSE17306 Multiple myeloma 0.003 4.9e-1 -0.004 4.9e-1 49 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
KIRP -0.329 0.03 -0.244 0.09 32 Click to see details
THCA -0.231 0.04 -0.152 0.13 59 Click to see details
HNSC 0.23 0.07 0.202 0.1 42 Click to see details
UCEC -0.334 0.08 -0.342 0.08 19 Click to see details
LUAD 0.397 0.1 0.231 0.24 12 Click to see details
KICH 0.228 0.14 0.138 0.26 25 Click to see details
CESC 0.898 0.15 0.500 0.33 3 Click to see details
PRAD 0.145 0.16 0.135 0.17 50 Click to see details
ESCA 0.302 0.18 0.227 0.25 11 Click to see details
BLCA -0.206 0.21 -0.154 0.27 18 Click to see details
STAD 0.15 0.21 0.134 0.23 32 Click to see details
PAAD -0.532 0.23 -0.800 0.1 4 Click to see details
CHOL -0.254 0.25 -0.200 0.3 9 Click to see details
PCPG 0.66 0.27 0.500 0.33 3 Click to see details
LIHC -0.058 0.35 0.011 0.47 49 Click to see details
BRCA -0.042 0.35 0.056 0.31 84 Click to see details
KIRC 0.035 0.39 0.088 0.24 68 Click to see details
LUSC -0.039 0.41 0.018 0.46 38 Click to see details
COAD -0.098 0.41 -0.119 0.39 8 Click to see details
COAD -0.098 0.41 -0.119 0.39 8 Click to see details
COAD -0.098 0.41 -0.119 0.39 8 Click to see details
1196 hsa-miR-93-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT000021 TP53INP1 tumor protein p53 inducible nuclear protein 1 5 3
MIRT000577 CDKN1A cyclin dependent kinase inhibitor 1A 6 5
MIRT002471 TCEAL1 transcription elongation factor A like 1 1 1
MIRT002472 E2F1 E2F transcription factor 1 5 5
MIRT003240 MAPK9 mitogen-activated protein kinase 9 2 1
MIRT004055 VEGFA vascular endothelial growth factor A 2 1
MIRT004104 ITGB8 integrin subunit beta 8 4 1
MIRT004332 KAT2B lysine acetyltransferase 2B 3 1
MIRT004410 TUSC2 tumor suppressor candidate 2 4 3
MIRT004572 BCL2L11 BCL2 like 11 2 9
MIRT006216 PTEN phosphatase and tensin homolog 4 3
MIRT007003 PURA purine rich element binding protein A 1 1
MIRT007185 LATS2 large tumor suppressor kinase 2 3 1
MIRT027939 TAF6L TATA-box binding protein associated factor 6 like 1 1
MIRT027940 LDLR low density lipoprotein receptor 2 9
MIRT027941 PDZD11 PDZ domain containing 11 1 2
MIRT027942 ZNF813 zinc finger protein 813 1 1
MIRT027943 ARSJ arylsulfatase family member J 2 3
MIRT027944 TMEM100 transmembrane protein 100 2 3
MIRT027945 ADARB1 adenosine deaminase, RNA specific B1 1 1
MIRT027946 LIMA1 LIM domain and actin binding 1 2 5
MIRT027947 LUZP1 leucine zipper protein 1 1 1
MIRT027948 AP1G1 adaptor related protein complex 1 gamma 1 subunit 1 2
MIRT027949 TMEM127 transmembrane protein 127 2 9
MIRT027950 ZIC5 Zic family member 5 1 1
MIRT027951 ZNF202 zinc finger protein 202 2 6
MIRT027952 TSN translin 1 1
MIRT027953 TMX3 thioredoxin related transmembrane protein 3 1 2
MIRT027954 SUCO SUN domain containing ossification factor 2 6
MIRT027955 ACIN1 apoptotic chromatin condensation inducer 1 1 1
MIRT027956 RND3 Rho family GTPase 3 1 1
MIRT027957 RYBP RING1 and YY1 binding protein 1 1
MIRT027958 RAB11FIP1 RAB11 family interacting protein 1 2 6
MIRT027959 EPHA4 EPH receptor A4 2 4
MIRT027960 TMEM168 transmembrane protein 168 1 1
MIRT027961 DCTN6 dynactin subunit 6 2 3
MIRT027962 SPTBN1 spectrin beta, non-erythrocytic 1 1 1
MIRT027963 NUPL1 nucleoporin 58 1 1
MIRT027964 HAUS8 HAUS augmin like complex subunit 8 2 3
MIRT027965 GRB2 growth factor receptor bound protein 2 1 1
MIRT027966 CCNG2 cyclin G2 1 1
MIRT027967 KATNAL1 katanin catalytic subunit A1 like 1 2 4
MIRT027968 CAPRIN2 caprin family member 2 2 6
MIRT027969 FAM129A family with sequence similarity 129 member A 2 7
MIRT027970 GNB4 G protein subunit beta 4 1 1
MIRT027971 C5orf22 chromosome 5 open reading frame 22 1 1
MIRT027972 DMKN dermokine 1 1
MIRT027973 SPOPL speckle type BTB/POZ protein like 1 2
MIRT027974 TGFBR2 transforming growth factor beta receptor 2 6 8
MIRT027975 RPA2 replication protein A2 1 2
MIRT027976 ATP5SL distal membrane arm assembly complex 2 1 1
MIRT027977 RAB5B RAB5B, member RAS oncogene family 2 9
MIRT027978 AKAP11 A-kinase anchoring protein 11 2 12
MIRT027979 COQ2 coenzyme Q2, polyprenyltransferase 1 1
MIRT027980 GPR137C G protein-coupled receptor 137C 1 1
MIRT027981 NIN ninein 2 5
MIRT027982 BMPR2 bone morphogenetic protein receptor type 2 1 2
MIRT027983 LIX1L limb and CNS expressed 1 like 1 1
MIRT027984 ARHGAP12 Rho GTPase activating protein 12 2 5
MIRT027985 ZFP91 ZFP91 zinc finger protein 1 1
MIRT027986 PRKACB protein kinase cAMP-activated catalytic subunit beta 2 3
MIRT027987 NACC2 NACC family member 2 2 4
MIRT027988 ATP6V1G2-DDX39B ATP6V1G2-DDX39B readthrough (NMD candidate) 1 1
MIRT027989 YTHDC1 YTH domain containing 1 2 3
MIRT027990 NDEL1 nudE neurodevelopment protein 1 like 1 1 1
MIRT027991 NR2C2AP nuclear receptor 2C2 associated protein 1 1
MIRT027992 HCCS holocytochrome c synthase 1 1
MIRT027993 ZNF417 zinc finger protein 417 2 6
MIRT027994 IRF1 interferon regulatory factor 1 1 1
MIRT027995 SERTAD2 SERTA domain containing 2 1 1
MIRT027996 BNIP2 BCL2 interacting protein 2 2 7
MIRT027997 FMNL2 formin like 2 2 3
MIRT027998 PHC3 polyhomeotic homolog 3 1 1
MIRT027999 SYBU syntabulin 1 1
MIRT028000 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 10
MIRT028001 WDR33 WD repeat domain 33 1 1
MIRT028002 CCND1 cyclin D1 2 12
MIRT028003 PBXIP1 PBX homeobox interacting protein 1 1 1
MIRT028004 SMAD4 SMAD family member 4 2 6
MIRT028005 ZNF805 zinc finger protein 805 2 3
MIRT028006 CRY2 cryptochrome circadian clock 2 1 2
MIRT028007 PBX3 PBX homeobox 3 1 1
MIRT028008 ZADH2 zinc binding alcohol dehydrogenase domain containing 2 1 1
MIRT028009 ZNF264 zinc finger protein 264 2 6
MIRT028010 LRRC58 leucine rich repeat containing 58 1 1
MIRT028011 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 6
MIRT028012 RUNX3 runt related transcription factor 3 2 2
MIRT028013 NUP107 nucleoporin 107 1 1
MIRT028014 SNAPIN SNAP associated protein 1 1
MIRT028015 ACTR2 ARP2 actin related protein 2 homolog 2 6
MIRT028016 SRPK1 SRSF protein kinase 1 1 1
MIRT028017 PBRM1 polybromo 1 1 1
MIRT028018 CD46 CD46 molecule 1 1
MIRT028019 SFXN5 sideroflexin 5 1 1
MIRT028020 USP21 ubiquitin specific peptidase 21 1 1
MIRT028021 ATXN1 ataxin 1 2 4
MIRT028022 ZMIZ1 zinc finger MIZ-type containing 1 1 1
MIRT028023 RNF34 ring finger protein 34 2 3
MIRT028024 ZC3H12C zinc finger CCCH-type containing 12C 2 8
MIRT028025 GRAMD1A GRAM domain containing 1A 1 2
MIRT028026 EGLN3 egl-9 family hypoxia inducible factor 3 2 3
MIRT028027 ZNF180 zinc finger protein 180 2 7
MIRT028028 DDX46 DEAD-box helicase 46 1 1
MIRT028029 KDM3B lysine demethylase 3B 1 1
MIRT028030 ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 1 1
MIRT028031 RMDN3 regulator of microtubule dynamics 3 1 1
MIRT028032 HOOK1 hook microtubule tethering protein 1 1 1
MIRT028033 RB1 RB transcriptional corepressor 1 2 3
MIRT028034 NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit 1 1
MIRT028035 FIGNL1 fidgetin like 1 1 1
MIRT028036 LYST lysosomal trafficking regulator 1 1
MIRT028037 TNFRSF21 TNF receptor superfamily member 21 2 4
MIRT028038 PDRG1 p53 and DNA damage regulated 1 2 10
MIRT028039 OTUD4 OTU deubiquitinase 4 2 2
MIRT028040 DUSP8 dual specificity phosphatase 8 1 1
MIRT028041 STC2 stanniocalcin 2 1 1
MIRT028042 UBXN2A UBX domain protein 2A 2 4
MIRT028043 ANKFY1 ankyrin repeat and FYVE domain containing 1 1 2
MIRT028044 TOLLIP toll interacting protein 1 1
MIRT028045 PPP6R2 protein phosphatase 6 regulatory subunit 2 1 1
MIRT028046 MAP7 microtubule associated protein 7 2 8
MIRT028047 ZBTB21 zinc finger and BTB domain containing 21 1 1
MIRT028048 TNKS1BP1 tankyrase 1 binding protein 1 1 1
MIRT028049 CSNK1G1 casein kinase 1 gamma 1 1 1
MIRT028050 ARID4B AT-rich interaction domain 4B 2 6
MIRT028051 FOXJ3 forkhead box J3 2 4
MIRT028052 VMA21 VMA21, vacuolar ATPase assembly factor 1 1
MIRT028053 BTG3 BTG anti-proliferation factor 3 2 8
MIRT028054 HARS histidyl-tRNA synthetase 1 1
MIRT028055 TAX1BP1 Tax1 binding protein 1 2 5
MIRT028056 NFIB nuclear factor I B 2 5
MIRT028057 REV3L REV3 like, DNA directed polymerase zeta catalytic subunit 1 1
MIRT028058 GPN3 GPN-loop GTPase 3 1 1
MIRT028059 MZT1 mitotic spindle organizing protein 1 1 1
MIRT028060 DDX39B DExD-box helicase 39B 1 1
MIRT028061 RBBP7 RB binding protein 7, chromatin remodeling factor 1 2
MIRT028062 ARCN1 archain 1 1 2
MIRT028063 C16orf70 chromosome 16 open reading frame 70 2 4
MIRT028064 ZBTB33 zinc finger and BTB domain containing 33 2 6
MIRT028065 LAPTM4B lysosomal protein transmembrane 4 beta 1 1
MIRT028066 MYO1E myosin IE 1 1
MIRT028067 TYW5 tRNA-yW synthesizing protein 5 1 1
MIRT028068 LHFPL2 LHFPL tetraspan subfamily member 2 1 1
MIRT028069 ICMT isoprenylcysteine carboxyl methyltransferase 2 5
MIRT028070 C3orf38 chromosome 3 open reading frame 38 2 8
MIRT028071 MYLIP myosin regulatory light chain interacting protein 2 12
MIRT028072 FAM210A family with sequence similarity 210 member A 2 3
MIRT028073 YY1 YY1 transcription factor 1 2
MIRT028074 SGTB small glutamine rich tetratricopeptide repeat containing beta 2 4
MIRT028075 POGK pogo transposable element derived with KRAB domain 1 1
MIRT028076 PLEKHA1 pleckstrin homology domain containing A1 1 1
MIRT028077 MIDN midnolin 2 11
MIRT028078 DDX5 DEAD-box helicase 5 1 2
MIRT028079 EGR2 early growth response 2 1 1
MIRT028080 SUV420H1 lysine methyltransferase 5B 2 3
MIRT028081 MAPRE3 microtubule associated protein RP/EB family member 3 2 8
MIRT028082 CREBRF CREB3 regulatory factor 1 1
MIRT028083 FCHO2 FCH domain only 2 2 4
MIRT028084 PRRG1 proline rich and Gla domain 1 1 1
MIRT028085 SAMD12 sterile alpha motif domain containing 12 2 3
MIRT028086 PKD2 polycystin 2, transient receptor potential cation channel 1 1
MIRT028087 ARHGAP1 Rho GTPase activating protein 1 2 7
MIRT028088 B2M beta-2-microglobulin 2 10
MIRT028089 TBC1D20 TBC1 domain family member 20 1 1
MIRT028090 KLHL28 kelch like family member 28 2 9
MIRT028091 FBXL3 F-box and leucine rich repeat protein 3 1 1
MIRT028092 RHEBL1 RHEB like 1 1 1
MIRT028093 KMT2D lysine methyltransferase 2D 1 2
MIRT028094 ASB1 ankyrin repeat and SOCS box containing 1 1 2
MIRT028095 WDR1 WD repeat domain 1 1 2
MIRT028096 UBE3B ubiquitin protein ligase E3B 1 1
MIRT028097 FBXL5 F-box and leucine rich repeat protein 5 2 13
MIRT028098 GNA12 G protein subunit alpha 12 1 1
MIRT028099 ASF1A anti-silencing function 1A histone chaperone 1 1
MIRT028100 OSR1 odd-skipped related transciption factor 1 1 1
MIRT028101 SH3PXD2A SH3 and PX domains 2A 1 1
MIRT028102 CNOT4 CCR4-NOT transcription complex subunit 4 2 6
MIRT028103 FYCO1 FYVE and coiled-coil domain containing 1 1 2
MIRT028104 DCAF8 DDB1 and CUL4 associated factor 8 2 2
MIRT028105 YOD1 YOD1 deubiquitinase 2 4
MIRT028106 RRN3 RRN3 homolog, RNA polymerase I transcription factor 2 3
MIRT028107 UBR5 ubiquitin protein ligase E3 component n-recognin 5 1 2
MIRT028108 ANKRD52 ankyrin repeat domain 52 2 4
MIRT028109 SAMD8 sterile alpha motif domain containing 8 2 3
MIRT028110 MYO19 myosin XIX 1 1
MIRT028111 ADAR adenosine deaminase, RNA specific 2 5
MIRT028112 BTBD10 BTB domain containing 10 1 1
MIRT028113 SOWAHC sosondowah ankyrin repeat domain family member C 1 1
MIRT028114 REEP3 receptor accessory protein 3 2 4
MIRT028115 SEC23A Sec23 homolog A, coat complex II component 1 2
MIRT028116 PTPN4 protein tyrosine phosphatase, non-receptor type 4 2 9
MIRT028117 MTPAP mitochondrial poly(A) polymerase 2 5
MIRT028118 SPRED1 sprouty related EVH1 domain containing 1 2 3
MIRT028119 KLF9 Kruppel like factor 9 1 1
MIRT028120 DPP8 dipeptidyl peptidase 8 1 1
MIRT028121 FRS2 fibroblast growth factor receptor substrate 2 2 3
MIRT028122 STK11 serine/threonine kinase 11 1 1
MIRT028123 GPATCH2 G-patch domain containing 2 1 1
MIRT028124 NHLRC3 NHL repeat containing 3 1 2
MIRT028125 ANKRD29 ankyrin repeat domain 29 1 1
MIRT028126 STYX serine/threonine/tyrosine interacting protein 1 1
MIRT028127 PAPOLA poly(A) polymerase alpha 1 1
MIRT028128 ACPL2 2-phosphoxylose phosphatase 1 1 1
MIRT028129 MLLT6 MLLT6, PHD finger containing 1 1
MIRT028130 CD164 CD164 molecule 1 1
MIRT028131 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 1 1
MIRT028132 KLF11 Kruppel like factor 11 1 1
MIRT028133 TAF6 TATA-box binding protein associated factor 6 1 1
MIRT028134 SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 2 3
MIRT028135 UBE2J1 ubiquitin conjugating enzyme E2 J1 1 1
MIRT028136 CAV2 caveolin 2 1 1
MIRT028137 VLDLR very low density lipoprotein receptor 1 1
MIRT028138 WIZ widely interspaced zinc finger motifs 1 1
MIRT028139 C1orf63 arginine and serine rich protein 1 1 2
MIRT028140 PHF10 PHD finger protein 10 1 1
MIRT028141 RRAS2 RAS related 2 2 2
MIRT028142 ZBTB41 zinc finger and BTB domain containing 41 1 1
MIRT028143 SRSF2 serine and arginine rich splicing factor 2 2 5
MIRT028144 WDR26 WD repeat domain 26 1 1
MIRT028145 CPPED1 calcineurin like phosphoesterase domain containing 1 1 1
MIRT028146 F3 coagulation factor III, tissue factor 2 8
MIRT028147 MED12L mediator complex subunit 12 like 1 1
MIRT028148 PDE3B phosphodiesterase 3B 1 1
MIRT028149 NUAK1 NUAK family kinase 1 1 1
MIRT028150 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 2 4
MIRT028151 TSG101 tumor susceptibility 101 2 6
MIRT028152 EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 1 2
MIRT028153 ZNF143 zinc finger protein 143 1 1
MIRT028154 ZNF217 zinc finger protein 217 1 1
MIRT028155 ARL1 ADP ribosylation factor like GTPase 1 1 2
MIRT028156 FKBP7 FK506 binding protein 7 1 1
MIRT028157 RNF145 ring finger protein 145 1 1
MIRT028158 CERS2 ceramide synthase 2 1 1
MIRT028159 SLC5A3 solute carrier family 5 member 3 2 4
MIRT028160 TRIP10 thyroid hormone receptor interactor 10 4 4
MIRT028161 AGO1 argonaute 1, RISC catalytic component 1 3
MIRT028162 PCID2 PCI domain containing 2 1 1
MIRT028163 DCTN4 dynactin subunit 4 1 1
MIRT028164 MAN1C1 mannosidase alpha class 1C member 1 1 1
MIRT028165 UBR1 ubiquitin protein ligase E3 component n-recognin 1 1 1
MIRT028166 MED13L mediator complex subunit 13 like 1 1
MIRT028167 PRUNE2 prune homolog 2 1 1
MIRT028168 CALCOCO2 calcium binding and coiled-coil domain 2 1 1
MIRT028169 SGMS1 sphingomyelin synthase 1 2 3
MIRT028170 DSTYK dual serine/threonine and tyrosine protein kinase 1 1
MIRT028171 C18orf32 chromosome 18 open reading frame 32 2 2
MIRT028172 EPHA7 EPH receptor A7 1 1
MIRT028173 PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 1 2
MIRT028174 IKZF4 IKAROS family zinc finger 4 1 1
MIRT028175 HEG1 heart development protein with EGF like domains 1 1 1
MIRT028176 FEM1C fem-1 homolog C 2 9
MIRT028177 CDC37L1 cell division cycle 37 like 1 1 1
MIRT028178 STAT3 signal transducer and activator of transcription 3 1 2
MIRT028179 ZNF148 zinc finger protein 148 1 1
MIRT028180 PGM2L1 phosphoglucomutase 2 like 1 1 2
MIRT028181 EFCAB14 EF-hand calcium binding domain 14 2 3
MIRT048739 ZIC2 Zic family member 2 1 1
MIRT048740 POLR2A RNA polymerase II subunit A 1 1
MIRT048741 SET SET nuclear proto-oncogene 1 1
MIRT048742 MTSS1L MTSS1L, I-BAR domain containing 1 1
MIRT048743 MICALL1 MICAL like 1 1 1
MIRT048744 GRSF1 G-rich RNA sequence binding factor 1 1 1
MIRT048745 RAB8B RAB8B, member RAS oncogene family 1 1
MIRT048746 UBE2M ubiquitin conjugating enzyme E2 M 1 1
MIRT048747 ZC3H7A zinc finger CCCH-type containing 7A 1 1
MIRT048748 PGAM1 phosphoglycerate mutase 1 1 1
MIRT048749 BAZ2A bromodomain adjacent to zinc finger domain 2A 1 1
MIRT048750 DZIP3 DAZ interacting zinc finger protein 3 1 1
MIRT048751 KPNA2 karyopherin subunit alpha 2 2 12
MIRT048752 ITPA inosine triphosphatase 1 1
MIRT048753 FAM3C family with sequence similarity 3 member C 1 1
MIRT048754 ELAVL1 ELAV like RNA binding protein 1 1 1
MIRT048755 TAF8 TATA-box binding protein associated factor 8 1 1
MIRT048756 AP2A2 adaptor related protein complex 2 alpha 2 subunit 1 1
MIRT048757 RPL7A ribosomal protein L7a 1 1
MIRT048758 SAMD4B sterile alpha motif domain containing 4B 1 1
MIRT048759 EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1 1
MIRT048760 ZBTB7A zinc finger and BTB domain containing 7A 2 4
MIRT048761 GAPDH glyceraldehyde-3-phosphate dehydrogenase 1 1
MIRT048762 SEC23IP SEC23 interacting protein 1 1
MIRT048763 ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 1 1
MIRT048764 RPL9 ribosomal protein L9 1 1
MIRT048765 HNRNPM heterogeneous nuclear ribonucleoprotein M 1 1
MIRT048766 MOB1A MOB kinase activator 1A 1 1
MIRT048767 STX16 syntaxin 16 1 1
MIRT048768 CDHR1 cadherin related family member 1 1 1
MIRT048769 C6orf62 chromosome 6 open reading frame 62 1 1
MIRT048770 TRAM1 translocation associated membrane protein 1 1 1
MIRT048771 MFN2 mitofusin 2 1 1
MIRT048772 UBE2L3 ubiquitin conjugating enzyme E2 L3 1 1
MIRT048773 RPL30 ribosomal protein L30 1 1
MIRT048774 CTC1 CST telomere replication complex component 1 1 1
MIRT048775 CAP1 cyclase associated actin cytoskeleton regulatory protein 1 1 1
MIRT048776 NONO non-POU domain containing octamer binding 1 1
MIRT048777 DNMT3B DNA methyltransferase 3 beta 1 1
MIRT048778 EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1 1
MIRT048779 RBM23 RNA binding motif protein 23 1 1
MIRT048780 UBAP2L ubiquitin associated protein 2 like 1 1
MIRT048781 RPL27 ribosomal protein L27 1 1
MIRT048782 HIST3H2A histone cluster 3 H2A 1 1
MIRT048783 HDDC2 HD domain containing 2 1 1
MIRT048784 GRID2IP Grid2 interacting protein 1 1
MIRT048785 PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H 1 1
MIRT048786 PRKCI protein kinase C iota 1 1
MIRT048787 NPEPPS aminopeptidase puromycin sensitive 1 1
MIRT048788 CBX3 chromobox 3 1 1
MIRT048789 FAH fumarylacetoacetate hydrolase 1 1
MIRT048790 RIF1 replication timing regulatory factor 1 1 1
MIRT048791 ZSWIM1 zinc finger SWIM-type containing 1 1 1
MIRT048792 POLE DNA polymerase epsilon, catalytic subunit 1 1
MIRT048793 LRP3 LDL receptor related protein 3 1 1
MIRT048794 CCT8 chaperonin containing TCP1 subunit 8 1 1
MIRT048795 KIAA1191 KIAA1191 2 6
MIRT048796 GPS1 G protein pathway suppressor 1 1 1
MIRT048797 BAG2 BCL2 associated athanogene 2 1 1
MIRT048798 ARHGAP32 Rho GTPase activating protein 32 1 1
MIRT048799 SLC19A1 solute carrier family 19 member 1 1 1
MIRT048800 NUBP1 nucleotide binding protein 1 1 1
MIRT048801 ARL9 ADP ribosylation factor like GTPase 9 1 1
MIRT048802 PSMD11 proteasome 26S subunit, non-ATPase 11 1 1
MIRT048803 UBE2O ubiquitin conjugating enzyme E2 O 1 1
MIRT048804 TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 1 1
MIRT048805 APBB2 amyloid beta precursor protein binding family B member 2 1 1
MIRT048806 BIRC5 baculoviral IAP repeat containing 5 1 1
MIRT048807 H1F0 H1 histone family member 0 1 1
MIRT048808 PRPF8 pre-mRNA processing factor 8 1 1
MIRT048809 DVL3 dishevelled segment polarity protein 3 1 1
MIRT048810 MAP3K13 mitogen-activated protein kinase kinase kinase 13 1 1
MIRT048811 RPS6KA5 ribosomal protein S6 kinase A5 2 5
MIRT048812 TAF4 TATA-box binding protein associated factor 4 1 1
MIRT048813 HIST1H3B histone cluster 1 H3 family member b 1 1
MIRT048814 TBCC tubulin folding cofactor C 1 1
MIRT048815 FASN fatty acid synthase 1 1
MIRT048816 RFC3 replication factor C subunit 3 1 1
MIRT048817 CCDC88C coiled-coil domain containing 88C 1 1
MIRT048818 ZNF384 zinc finger protein 384 1 1
MIRT048819 APLP2 amyloid beta precursor like protein 2 1 1
MIRT048820 NOB1 NIN1/PSMD8 binding protein 1 homolog 1 1
MIRT048821 JUN Jun proto-oncogene, AP-1 transcription factor subunit 1 1
MIRT048822 PGP phosphoglycolate phosphatase 1 1
MIRT048823 XBP1 X-box binding protein 1 1 1
MIRT048824 NBPF15 NBPF member 15 1 1
MIRT048825 VAT1 vesicle amine transport 1 1 1
MIRT048826 PPTC7 PTC7 protein phosphatase homolog 1 1
MIRT048827 IPO5 importin 5 1 1
MIRT048828 HIST2H4B histone cluster 2 H4 family member b 1 1
MIRT048829 IP6K1 inositol hexakisphosphate kinase 1 1 1
MIRT048830 ARPC2 actin related protein 2/3 complex subunit 2 1 1
MIRT048831 KIAA1279 KIF1 binding protein 1 1
MIRT048832 PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 1 1
MIRT048833 SMG7 SMG7, nonsense mediated mRNA decay factor 1 1
MIRT048834 ELAC2 elaC ribonuclease Z 2 1 1
MIRT048835 NUP153 nucleoporin 153 1 1
MIRT048836 NUP205 nucleoporin 205 1 1
MIRT048837 MYO9B myosin IXB 1 1
MIRT048838 MAD2L1 mitotic arrest deficient 2 like 1 1 1
MIRT048839 SND1 staphylococcal nuclease and tudor domain containing 1 1 1
MIRT048840 MCM5 minichromosome maintenance complex component 5 1 1
MIRT048841 RNF44 ring finger protein 44 1 1
MIRT048842 IGF2 insulin like growth factor 2 1 1
MIRT048843 PFAS phosphoribosylformylglycinamidine synthase 1 1
MIRT048844 PI4KA phosphatidylinositol 4-kinase alpha 1 1
MIRT048845 HIST2H3A histone cluster 2 H3 family member a 1 1
MIRT048846 MAP3K4 mitogen-activated protein kinase kinase kinase 4 1 1
MIRT048847 N4BP1 NEDD4 binding protein 1 1 2
MIRT048848 GARS glycyl-tRNA synthetase 1 1
MIRT048849 CLN8 CLN8, transmembrane ER and ERGIC protein 1 1
MIRT048850 PSMD4 proteasome 26S subunit, non-ATPase 4 1 1
MIRT048851 NUP188 nucleoporin 188 1 1
MIRT048852 TRAK1 trafficking kinesin protein 1 1 1
MIRT048853 NR4A1 nuclear receptor subfamily 4 group A member 1 1 1
MIRT048854 DCTN1 dynactin subunit 1 1 1
MIRT048855 PAPD7 poly(A) RNA polymerase D7, non-canonical 1 1
MIRT048856 TRIM65 tripartite motif containing 65 1 1
MIRT048857 UPF1 UPF1, RNA helicase and ATPase 1 1
MIRT048858 SPATA2 spermatogenesis associated 2 1 1
MIRT048859 AP1AR adaptor related protein complex 1 associated regulatory protein 1 1
MIRT048860 NTHL1 nth like DNA glycosylase 1 1 1
MIRT048861 HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 1 1
MIRT048862 MARK2 microtubule affinity regulating kinase 2 1 1
MIRT048863 SLC29A2 solute carrier family 29 member 2 1 1
MIRT048864 ZBTB3 zinc finger and BTB domain containing 3 1 1
MIRT048865 FOXRED2 FAD dependent oxidoreductase domain containing 2 2 3
MIRT048866 SEC16A SEC16 homolog A, endoplasmic reticulum export factor 1 2
MIRT048867 XYLT2 xylosyltransferase 2 1 1
MIRT048868 ZCCHC14 zinc finger CCHC-type containing 14 1 1
MIRT048869 HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 1 1
MIRT048870 UBN1 ubinuclein 1 1 1
MIRT048871 UNC45A unc-45 myosin chaperone A 1 1
MIRT048872 VAMP7 vesicle associated membrane protein 7 1 1
MIRT048873 KIAA1715 lunapark, ER junction formation factor 1 1
MIRT048874 ANAPC5 anaphase promoting complex subunit 5 1 1
MIRT048875 NPM1 nucleophosmin 1 1 1
MIRT048876 SLC9A6 solute carrier family 9 member A6 1 1
MIRT048877 ZNF706 zinc finger protein 706 1 1
MIRT048878 PYGL glycogen phosphorylase L 1 1
MIRT048879 ZNFX1 zinc finger NFX1-type containing 1 2 6
MIRT048880 TLE3 transducin like enhancer of split 3 1 1
MIRT048881 LOXL1 lysyl oxidase like 1 1 1
MIRT048882 MPG N-methylpurine DNA glycosylase 1 1
MIRT048883 IBA57 IBA57 homolog, iron-sulfur cluster assembly 1 1
MIRT048884 KLHDC2 kelch domain containing 2 1 1
MIRT048885 HDGF heparin binding growth factor 1 1
MIRT048886 YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta 1 1
MIRT048887 SH3BP4 SH3 domain binding protein 4 1 1
MIRT048888 DAPK3 death associated protein kinase 3 1 1
MIRT048889 CRELD2 cysteine rich with EGF like domains 2 1 1
MIRT048890 CCDC47 coiled-coil domain containing 47 1 1
MIRT048891 EIF4G2 eukaryotic translation initiation factor 4 gamma 2 1 2
MIRT048892 RMND5B required for meiotic nuclear division 5 homolog B 1 1
MIRT048893 TELO2 telomere maintenance 2 1 1
MIRT048894 HK1 hexokinase 1 1 1
MIRT048895 TYSND1 trypsin domain containing 1 1 1
MIRT048896 ERLIN2 ER lipid raft associated 2 1 1
MIRT048897 TRPC4AP transient receptor potential cation channel subfamily C member 4 associated protein 1 1
MIRT048898 FAM57A family with sequence similarity 57 member A 1 2
MIRT048899 ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 1 1
MIRT048900 ATP6 ATP synthase F0 subunit 6 1 1
MIRT048901 RNF220 ring finger protein 220 1 1
MIRT048902 SMG6 SMG6, nonsense mediated mRNA decay factor 1 1
MIRT048903 KLB klotho beta 1 1
MIRT048904 HPS1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 1 1
MIRT048905 MED21 mediator complex subunit 21 1 1
MIRT048906 NBEAL2 neurobeachin like 2 1 1
MIRT048907 ZNF76 zinc finger protein 76 1 1
MIRT048908 UQCRC1 ubiquinol-cytochrome c reductase core protein I 1 1
MIRT048909 GLI3 GLI family zinc finger 3 1 1
MIRT048910 CDC16 cell division cycle 16 1 1
MIRT048911 EAPP E2F associated phosphoprotein 1 1
MIRT048912 PPAN peter pan homolog (Drosophila) 1 1
MIRT048913 WAC WW domain containing adaptor with coiled-coil 2 7
MIRT048914 TRIM8 tripartite motif containing 8 1 2
MIRT052990 Sp7 Sp7 transcription factor 7 2 1
MIRT053085 SLC2A4 solute carrier family 2 member 4 3 1
MIRT053624 ATG16L1 autophagy related 16 like 1 3 2
MIRT053634 DAB2 DAB2, clathrin adaptor protein 4 1
MIRT053874 SMAD7 SMAD family member 7 3 1
MIRT054116 UNKL unkempt family like zinc finger 1 1
MIRT054255 ZBTB4 zinc finger and BTB domain containing 4 5 8
MIRT055021 TPRG1L tumor protein p63 regulated 1 like 2 3
MIRT055384 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 6
MIRT055650 WDR37 WD repeat domain 37 1 1
MIRT056477 PFKP phosphofructokinase, platelet 2 9
MIRT057385 TNKS2 tankyrase 2 2 3
MIRT057823 SLC30A7 solute carrier family 30 member 7 2 2
MIRT058913 FAM46C family with sequence similarity 46 member C 1 1
MIRT060076 TMEM138 transmembrane protein 138 1 1
MIRT060498 PPP6R3 protein phosphatase 6 regulatory subunit 3 2 2
MIRT060679 KLHL20 kelch like family member 20 1 1
MIRT061182 MED17 mediator complex subunit 17 2 3
MIRT061354 WEE1 WEE1 G2 checkpoint kinase 2 3
MIRT063055 ULK1 unc-51 like autophagy activating kinase 1 2 2
MIRT063436 SKI SKI proto-oncogene 1 1
MIRT064436 GPR137B G protein-coupled receptor 137B 2 4
MIRT064798 ZBTB18 zinc finger and BTB domain containing 18 2 3
MIRT065365 TMBIM6 transmembrane BAX inhibitor motif containing 6 1 1
MIRT065671 ACVR1B activin A receptor type 1B 2 6
MIRT065859 GDF11 growth differentiation factor 11 2 2
MIRT067230 FOXJ2 forkhead box J2 2 2
MIRT070742 HIF1A hypoxia inducible factor 1 alpha subunit 6 3
MIRT070840 EIF2S1 eukaryotic translation initiation factor 2 subunit alpha 2 4
MIRT070996 SMOC1 SPARC related modular calcium binding 1 2 2
MIRT071325 CMPK1 cytidine/uridine monophosphate kinase 1 1 1
MIRT071904 ZFYVE9 zinc finger FYVE-type containing 9 2 2
MIRT072568 USP3 ubiquitin specific peptidase 3 1 1
MIRT073118 UBE2Q2 ubiquitin conjugating enzyme E2 Q2 1 1
MIRT073377 ABHD2 abhydrolase domain containing 2 1 1
MIRT073408 SEMA4B semaphorin 4B 1 1
MIRT074790 CYLD CYLD lysine 63 deubiquitinase 1 1
MIRT074892 CHD9 chromodomain helicase DNA binding protein 9 1 1
MIRT075776 KIAA0513 KIAA0513 2 6
MIRT076178 GID4 GID complex subunit 4 homolog 2 5
MIRT077065 KRT10 keratin 10 2 8
MIRT077832 MINK1 misshapen like kinase 1 2 3
MIRT078812 UNK unkempt family zinc finger 2 2
MIRT079345 CCDC137 coiled-coil domain containing 137 2 3
MIRT079412 FOXK2 forkhead box K2 2 5
MIRT079773 CABLES1 Cdk5 and Abl enzyme substrate 1 2 2
MIRT080849 RAB12 RAB12, member RAS oncogene family 1 1
MIRT082292 FNBP1L formin binding protein 1 like 2 6
MIRT083740 PARD6B par-6 family cell polarity regulator beta 1 1
MIRT083961 RAB22A RAB22A, member RAS oncogene family 2 5
MIRT084345 RRM2 ribonucleotide reductase regulatory subunit M2 2 3
MIRT085868 TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 1 1
MIRT086426 NABP1 nucleic acid binding protein 1 2 7
MIRT088128 SEPT2 septin 2 2 5
MIRT090634 U2SURP U2 snRNP associated SURP domain containing 2 7
MIRT093801 KLF3 Kruppel like factor 3 2 2
MIRT093942 SLAIN2 SLAIN motif family member 2 1 1
MIRT095201 SMAD5 SMAD family member 5 1 1
MIRT095720 ANKH ANKH inorganic pyrophosphate transport regulator 2 8
MIRT095998 ATP6V0E1 ATPase H+ transporting V0 subunit e1 1 1
MIRT096309 SQSTM1 sequestosome 1 1 1
MIRT097604 POLR3G RNA polymerase III subunit G 1 1
MIRT097650 LYSMD3 LysM domain containing 3 1 1
MIRT098786 SASH1 SAM and SH3 domain containing 1 2 1
MIRT098905 SNX9 sorting nexin 9 2 1
MIRT099309 QKI QKI, KH domain containing RNA binding 2 4
MIRT099356 C6ORF120 chromosome 6 open reading frame 120 1 1
MIRT099825 SOX4 SRY-box 4 2 10
MIRT100278 MICB MHC class I polypeptide-related sequence B 1 1
MIRT100455 ZBTB9 zinc finger and BTB domain containing 9 1 1
MIRT100946 CENPQ centromere protein Q 2 4
MIRT102222 HBP1 HMG-box transcription factor 1 2 3
MIRT102295 DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 2 10
MIRT103191 SP4 Sp4 transcription factor 2 6
MIRT104162 PHTF2 putative homeodomain transcription factor 2 2 6
MIRT104397 ANKIB1 ankyrin repeat and IBR domain containing 1 1 1
MIRT108720 XIAP X-linked inhibitor of apoptosis 2 2
MIRT110268 GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 1 1
MIRT112090 TIMM17A translocase of inner mitochondrial membrane 17A 2 6
MIRT115781 CAPN15 calpain 15 2 2
MIRT121801 GRPEL2 GrpE like 2, mitochondrial 1 1
MIRT122364 RGMB repulsive guidance molecule family member b 2 4
MIRT124126 GINS4 GINS complex subunit 4 2 4
MIRT126309 ACADSB acyl-CoA dehydrogenase, short/branched chain 1 1
MIRT126345 ZRANB1 zinc finger RANBP2-type containing 1 1 1
MIRT126551 MASTL microtubule associated serine/threonine kinase like 2 3
MIRT127162 VPS26A VPS26, retromer complex component A 1 1
MIRT130073 TXNIP thioredoxin interacting protein 2 5
MIRT132395 PPP1R12B protein phosphatase 1 regulatory subunit 12B 1 1
MIRT133314 ORAI1 ORAI calcium release-activated calcium modulator 1 1 1
MIRT134276 DNM1L dynamin 1 like 1 1
MIRT135707 PIP4K2C phosphatidylinositol-5-phosphate 4-kinase type 2 gamma 1 1
MIRT135794 GNS glucosamine (N-acetyl)-6-sulfatase 2 7
MIRT136563 TXLNA taxilin alpha 1 1
MIRT138112 BRMS1L breast cancer metastasis-suppressor 1 like 1 1
MIRT138351 FRMD6 FERM domain containing 6 1 1
MIRT138794 SUSD6 sushi domain containing 6 1 1
MIRT140631 PLEKHO2 pleckstrin homology domain containing O2 1 1
MIRT140798 SMAD6 SMAD family member 6 1 1
MIRT141127 SCAMP5 secretory carrier membrane protein 5 1 1
MIRT141699 RCCD1 RCC1 domain containing 1 1 1
MIRT142096 CCP110 centriolar coiled-coil protein 110 1 1
MIRT142384 TNRC6A trinucleotide repeat containing 6A 1 1
MIRT144210 SNTB2 syntrophin beta 2 1 1
MIRT144298 NFAT5 nuclear factor of activated T-cells 5 2 9
MIRT144979 PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 1 1
MIRT145021 TNFAIP1 TNF alpha induced protein 1 1 1
MIRT145598 LASP1 LIM and SH3 protein 1 2 3
MIRT146072 RUNDC1 RUN domain containing 1 1 1
MIRT147119 MAP3K3 mitogen-activated protein kinase kinase kinase 3 1 1
MIRT147922 CAMTA1 calmodulin binding transcription activator 1 1 1
MIRT148869 ANKRD12 ankyrin repeat domain 12 1 1
MIRT151693 CHAF1A chromatin assembly factor 1 subunit A 1 1
MIRT151801 BLOC1S3 biogenesis of lysosomal organelles complex 1 subunit 3 1 1
MIRT151854 ARHGAP35 Rho GTPase activating protein 35 1 1
MIRT151935 TBC1D17 TBC1 domain family member 17 1 1
MIRT152368 ARHGEF18 Rho/Rac guanine nucleotide exchange factor 18 1 1
MIRT152674 POFUT1 protein O-fucosyltransferase 1 1 1
MIRT153328 MAVS mitochondrial antiviral signaling protein 2 4
MIRT153455 TTPAL alpha tocopherol transfer protein like 1 1
MIRT153614 NCOA3 nuclear receptor coactivator 3 1 1
MIRT153970 PRNP prion protein 2 3
MIRT155234 IFNAR2 interferon alpha and beta receptor subunit 2 1 1
MIRT155334 IFNAR1 interferon alpha and beta receptor subunit 1 1 1
MIRT155889 SIK1 salt inducible kinase 1 2 2
MIRT156406 RAPGEF4 Rap guanine nucleotide exchange factor 4 1 1
MIRT156643 C2ORF69 chromosome 2 open reading frame 69 1 1
MIRT157146 FAM117B family with sequence similarity 117 member B 1 1
MIRT157586 MTMR3 myotubularin related protein 3 1 1
MIRT158574 TNRC6B trinucleotide repeat containing 6B 2 2
MIRT159108 NRBP1 nuclear receptor binding protein 1 2 3
MIRT159400 FEZ2 fasciculation and elongation protein zeta 2 1 1
MIRT160005 TET3 tet methylcytosine dioxygenase 3 1 1
MIRT160842 PLXNA1 plexin A1 1 1
MIRT164200 GAB1 GRB2 associated binding protein 1 1 1
MIRT164525 MSMO1 methylsterol monooxygenase 1 4 4
MIRT164660 WHSC1 nuclear receptor binding SET domain protein 2 1 1
MIRT164721 ADD1 adducin 1 1 1
MIRT166063 FAF2 Fas associated factor family member 2 1 1
MIRT167841 HECA hdc homolog, cell cycle regulator 1 1
MIRT168217 BTN3A2 butyrophilin subfamily 3 member A2 1 1
MIRT168279 BTN3A1 butyrophilin subfamily 3 member A1 1 1
MIRT169664 AGFG2 ArfGAP with FG repeats 2 1 1
MIRT170566 CASP2 caspase 2 1 1
MIRT172198 OXR1 oxidation resistance 1 1 1
MIRT173113 E2F5 E2F transcription factor 5 1 1
MIRT173690 PRPF4 pre-mRNA processing factor 4 1 1
MIRT175380 ACSL4 acyl-CoA synthetase long chain family member 4 2 2
MIRT175596 OCRL OCRL, inositol polyphosphate-5-phosphatase 1 1
MIRT175645 PHF6 PHD finger protein 6 1 1
MIRT176083 CHIC1 cysteine rich hydrophobic domain 1 1 1
MIRT182518 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT187473 PCBP2 poly(rC) binding protein 2 2 4
MIRT194850 UBFD1 ubiquitin family domain containing 1 1 1
MIRT199107 ZNF532 zinc finger protein 532 2 2
MIRT205047 CREB1 cAMP responsive element binding protein 1 2 2
MIRT205282 STK11IP serine/threonine kinase 11 interacting protein 2 2
MIRT206193 RAB10 RAB10, member RAS oncogene family 2 4
MIRT208976 SKIL SKI like proto-oncogene 2 10
MIRT213204 REST RE1 silencing transcription factor 2 2
MIRT213322 KIAA0232 KIAA0232 2 2
MIRT216424 SERF1A small EDRK-rich factor 1A 2 2
MIRT216449 SERF1B small EDRK-rich factor 1B 2 2
MIRT216662 F2R coagulation factor II thrombin receptor 2 2
MIRT220120 CAV1 caveolin 1 2 2
MIRT222674 EIF4H eukaryotic translation initiation factor 4H 2 6
MIRT222909 CROT carnitine O-octanoyltransferase 1 1
MIRT224748 DPYSL2 dihydropyrimidinase like 2 2 2
MIRT224886 MAK16 MAK16 homolog 1 1
MIRT227327 TRIM32 tripartite motif containing 32 1 1
MIRT230966 PRRG4 proline rich and Gla domain 4 2 2
MIRT238173 ANKRD33B ankyrin repeat domain 33B 2 10
MIRT242197 TTC9 tetratricopeptide repeat domain 9 2 4
MIRT242658 SALL3 spalt like transcription factor 3 2 4
MIRT243779 AFF1 AF4/FMR2 family member 1 1 1
MIRT244163 E2F3 E2F transcription factor 3 1 1
MIRT244589 HOOK3 hook microtubule tethering protein 3 2 2
MIRT246961 TSKU tsukushi, small leucine rich proteoglycan 2 2
MIRT247080 CEP57 centrosomal protein 57 1 1
MIRT248851 SESN2 sestrin 2 1 1
MIRT250445 NFATC2IP nuclear factor of activated T-cells 2 interacting protein 1 1
MIRT254250 TRAPPC10 trafficking protein particle complex 10 1 1
MIRT257280 FOXC1 forkhead box C1 2 2
MIRT266050 FJX1 four jointed box 1 2 4
MIRT266854 SLC25A44 solute carrier family 25 member 44 2 2
MIRT280208 EIF2B2 eukaryotic translation initiation factor 2B subunit beta 2 2
MIRT283173 C16ORF52 chromosome 16 open reading frame 52 2 2
MIRT286947 SOCS7 suppressor of cytokine signaling 7 2 2
MIRT289573 KDM6B lysine demethylase 6B 6 3
MIRT291932 TPM4 tropomyosin 4 2 2
MIRT293646 PVR poliovirus receptor 2 4
MIRT296869 REV1 REV1, DNA directed polymerase 1 1
MIRT296914 NPAS2 neuronal PAS domain protein 2 2 1
MIRT299338 CYBRD1 cytochrome b reductase 1 1 1
MIRT302435 CLIP4 CAP-Gly domain containing linker protein family member 4 2 2
MIRT303490 NAGK N-acetylglucosamine kinase 2 6
MIRT322521 HMBOX1 homeobox containing 1 2 2
MIRT325511 PTPDC1 protein tyrosine phosphatase domain containing 1 2 2
MIRT363923 UBE2V2 ubiquitin conjugating enzyme E2 V2 2 2
MIRT368883 BCL2L2 BCL2 like 2 2 2
MIRT397685 ATXN7L3B ataxin 7 like 3B 2 2
MIRT400047 ADRBK2 G protein-coupled receptor kinase 3 2 2
MIRT437749 MXD1 MAX dimerization protein 1 2 1
MIRT437750 SLC16A9 solute carrier family 16 member 9 3 2
MIRT437751 MGLL monoglyceride lipase 2 1
MIRT437752 SNX16 sorting nexin 16 2 1
MIRT437753 EREG epiregulin 2 1
MIRT438035 ICAM1 intercellular adhesion molecule 1 1 1
MIRT438036 WNT2B Wnt family member 2B 1 1
MIRT438037 MYC MYC proto-oncogene, bHLH transcription factor 1 2
MIRT438038 HLA-F major histocompatibility complex, class I, F 1 1
MIRT438039 TGFB1 transforming growth factor beta 1 1 1
MIRT438087 IL8 C-X-C motif chemokine ligand 8 2 1
MIRT441876 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 2 2
MIRT442198 CCDC132 VPS50, EARP/GARPII complex subunit 2 2
MIRT442547 SLCO5A1 solute carrier organic anion transporter family member 5A1 2 2
MIRT442765 NRIP3 nuclear receptor interacting protein 3 2 2
MIRT442807 CEP170 centrosomal protein 170 2 4
MIRT443254 A1CF APOBEC1 complementation factor 2 2
MIRT443708 LLPH LLP homolog, long-term synaptic facilitation 2 2
MIRT444307 SREK1IP1 SREK1 interacting protein 1 2 2
MIRT444433 EMC1 ER membrane protein complex subunit 1 2 2
MIRT448320 WNK3 WNK lysine deficient protein kinase 3 2 2
MIRT448368 TSR1 TSR1, ribosome maturation factor 2 6
MIRT448641 NPNT nephronectin 2 2
MIRT448724 ITGA2 integrin subunit alpha 2 2 2
MIRT449169 SORCS2 sortilin related VPS10 domain containing receptor 2 2 2
MIRT450185 TMEM9B TMEM9 domain family member B 2 2
MIRT450918 CADM2 cell adhesion molecule 2 2 2
MIRT450953 ATAD2 ATPase family, AAA domain containing 2 2 2
MIRT458289 FUT10 fucosyltransferase 10 2 2
MIRT462123 AKR7A2 aldo-keto reductase family 7 member A2 2 2
MIRT463550 ZBTB5 zinc finger and BTB domain containing 5 2 4
MIRT464850 RPS27A ribosomal protein S27a 2 12
MIRT465535 PRICKLE4 prickle planar cell polarity protein 4 2 2
MIRT465840 TMEM64 transmembrane protein 64 2 3
MIRT466451 TFAM transcription factor A, mitochondrial 2 8
MIRT467491 SMIM13 small integral membrane protein 13 2 6
MIRT467897 SLC22A23 solute carrier family 22 member 23 2 2
MIRT468157 SGPL1 sphingosine-1-phosphate lyase 1 2 2
MIRT469856 PXK PX domain containing serine/threonine kinase like 2 8
MIRT470057 PTGFRN prostaglandin F2 receptor inhibitor 2 2
MIRT471007 PITPNA phosphatidylinositol transfer protein alpha 2 2
MIRT472057 NPAT nuclear protein, coactivator of histone transcription 2 3
MIRT472343 NETO2 neuropilin and tolloid like 2 2 4
MIRT473166 MLLT1 MLLT1, super elongation complex subunit 2 2
MIRT473810 MAP3K2 mitogen-activated protein kinase kinase kinase 2 5 3
MIRT473911 M6PR mannose-6-phosphate receptor, cation dependent 2 9
MIRT474595 KLF6 Kruppel like factor 6 2 2
MIRT475475 HSPA8 heat shock protein family A (Hsp70) member 8 2 6
MIRT476129 GPR157 G protein-coupled receptor 157 2 6
MIRT477114 FAM160B1 family with sequence similarity 160 member B1 2 6
MIRT477282 ERGIC2 ERGIC and golgi 2 2 2
MIRT478726 CSNK1A1 casein kinase 1 alpha 1 2 4
MIRT479036 COIL coilin 2 10
MIRT479063 CNOT6L CCR4-NOT transcription complex subunit 6 like 2 8
MIRT479264 CHSY1 chondroitin sulfate synthase 1 2 2
MIRT480569 BZW1 basic leucine zipper and W2 domains 1 2 2
MIRT480672 BSCL2 BSCL2, seipin lipid droplet biogenesis associated 2 2
MIRT480783 BMP2 bone morphogenetic protein 2 2 2
MIRT480952 BBX BBX, HMG-box containing 2 8
MIRT481345 ATL3 atlastin GTPase 3 2 3
MIRT481884 ANKRD50 ankyrin repeat domain 50 2 2
MIRT484869 ZNF70 zinc finger protein 70 2 4
MIRT484882 ZNF652 zinc finger protein 652 2 2
MIRT484918 ZFYVE26 zinc finger FYVE-type containing 26 2 4
MIRT485099 SLC30A1 solute carrier family 30 member 1 2 4
MIRT485189 PTP4A1 protein tyrosine phosphatase type IVA, member 1 2 4
MIRT485334 MYO1D myosin ID 2 2
MIRT485584 FOXQ1 forkhead box Q1 2 2
MIRT486025 LPAR2 lysophosphatidic acid receptor 2 2 2
MIRT489603 ZDHHC20 zinc finger DHHC-type containing 20 2 10
MIRT491803 ZFYVE21 zinc finger FYVE-type containing 21 2 8
MIRT492007 UGCG UDP-glucose ceramide glucosyltransferase 2 2
MIRT492379 SEMA7A semaphorin 7A (John Milton Hagen blood group) 2 2
MIRT492785 PDGFB platelet derived growth factor subunit B 2 2
MIRT493126 MKNK2 MAP kinase interacting serine/threonine kinase 2 2 7
MIRT493344 LAPTM4A lysosomal protein transmembrane 4 alpha 2 13
MIRT493614 HMGB3 high mobility group box 3 2 6
MIRT494075 DUSP2 dual specificity phosphatase 2 2 4
MIRT494434 BTG2 BTG anti-proliferation factor 2 5 5
MIRT496060 MORC1 MORC family CW-type zinc finger 1 2 2
MIRT500720 TRIM37 tripartite motif containing 37 2 2
MIRT502053 LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 2 6
MIRT502375 GIGYF1 GRB10 interacting GYF protein 1 2 9
MIRT502401 GATA6 GATA binding protein 6 2 8
MIRT503077 C11orf30 EMSY, BRCA2 interacting transcriptional repressor 2 9
MIRT503219 ACER2 alkaline ceramidase 2 2 2
MIRT503558 MDM2 MDM2 proto-oncogene 2 4
MIRT503606 ZNF780A zinc finger protein 780A 2 2
MIRT503803 ZNF12 zinc finger protein 12 2 7
MIRT503825 TMEM242 transmembrane protein 242 2 4
MIRT504096 C9orf40 chromosome 9 open reading frame 40 2 7
MIRT504637 MFSD8 major facilitator superfamily domain containing 8 2 6
MIRT505863 POLR1B RNA polymerase I subunit B 2 4
MIRT506278 PDPK1 3-phosphoinositide dependent protein kinase 1 2 2
MIRT506548 MORF4L1 mortality factor 4 like 1 2 8
MIRT506618 MARCH6 membrane associated ring-CH-type finger 6 2 8
MIRT506662 MAPK1 mitogen-activated protein kinase 1 2 5
MIRT506682 LZIC leucine zipper and CTNNBIP1 domain containing 2 4
MIRT506852 KIF23 kinesin family member 23 2 5
MIRT506871 KIAA1147 KIAA1147 2 2
MIRT506883 KIAA0101 PCNA clamp associated factor 2 4
MIRT506987 HNRNPR heterogeneous nuclear ribonucleoprotein R 2 2
MIRT507202 FZD9 frizzled class receptor 9 2 6
MIRT507435 ELK4 ELK4, ETS transcription factor 2 4
MIRT507943 BTF3L4 basic transcription factor 3 like 4 2 6
MIRT508572 CEP72 centrosomal protein 72 2 4
MIRT508741 ZNF682 zinc finger protein 682 2 4
MIRT508833 GPR155 G protein-coupled receptor 155 2 2
MIRT509126 BMP8B bone morphogenetic protein 8b 2 6
MIRT509741 EFCAB11 EF-hand calcium binding domain 11 2 4
MIRT510025 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 4
MIRT510875 RAN RAN, member RAS oncogene family 2 9
MIRT511084 NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 2 5
MIRT511260 KLHL36 kelch like family member 36 2 6
MIRT511316 KIAA1551 KIAA1551 2 2
MIRT511552 HMGB1 high mobility group box 1 2 6
MIRT513463 NARS asparaginyl-tRNA synthetase