miRTarBase - #MIRT032113


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pre-miRNA Information
pre-miRNA hsa-let-7d   
Genomic Coordinates chr9: 94178834 - 94178920
Synonyms LET7D, MIRNLET7D, hsa-let-7d, let-7d, MIRLET7D
Description Homo sapiens let-7d stem-loop
Comment The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-let-7d-5p
Sequence 8| AGAGGUAGUAGGUUGCAUAGUU |29
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 3 9 + 94178843 27292188 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1462778813 2 dbSNP
rs1467512593 13 dbSNP
rs1329655735 14 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol LARP4B   
Synonyms KIAA0217, LARP5
Description La ribonucleoprotein domain family member 4B
Transcript NM_015155   
Expression
Putative miRNA Targets on LARP4B
3'UTR of LARP4B
(miRNA target sites are highlighted)		 
>LARP4B|NM_015155|3'UTR
   1 AAACCGTACGTCTGGGAGGGGTCGCAGAGCGCTGTGTTAACCACAAACGAGACACTCTCCCACTCAGTGCGAGGGCGAGC
  81 CGCTGGTTAGGAGCTTGCAGTGTCTGAGGCCTGTGGGATCCTCAAGTTGGTTTTCTTCTGTGAGTTGGATTCTCCCCCTC
 161 TTGAAAAAAAATCGATTTTTCAGGATTTAATTAATACAAACCTTATTTTAGGTTGGTGCTTAACTGGAGGTGATGCATAA
 241 GTCTGATTTTTTTTTCCAAGATAGAAAAAGCATTTATCCTAACAAATTGGTATTTTTTATTAAGCCTCCATGTGGCTCTG
 321 AATGCAAGCTATATATAGTGAGTTTTTCTAAATTAAGGGAACTCTGCTTTTTTTTTTTTTTTTTAAGTAACTGGTCTGTA
 401 AGTGCATATCTCTAGAACGTCCCCGCAGATGAATGAGGGCCAGTGGCCTTGGCAGAGGCAGGTGTGGCCTCGTAGAGGCA
 481 GTGCTGGCCGCGCCAGGGCATCAGTGCTGATGTGGGAGCTGTGCTTCCACCTAAGCCGTTGGTAGGGGACTGTGGCATTT
 561 AAGAATGTAGAGAGCGCATCCTTTTTGATCTCCTGGGCGGAGTGAACCTGCAGGGGCCACCCCAGAAACCTTGGTTCTGA
 641 TGCACTGCAAGCAAGTAACCAGCTTCTCACTCCAGTTTCAAGTGGCTATTATGTAATATAAATTCAAAGCACATTGTGAA
 721 TAGAACCTACATGAAAACATACACTTTGTTGCCCACTGACATGTTACCAGAAGTTGTACCATGATGTTGTTTTGACCCCT
 801 GTGAGCTGATGGCCCCGGCCCTGCTCTGTGCACATTTCTGTCCGTGTTCCCCAGCACTCTGGTTGGAGAGAGTCCACATC
 881 TTCAGCTCCGTGTGGACATCTCCCTGTACCTCTGCATCAGCACATGGATTTAAGAGTTATGTAATCGTGAGAGAATGGTG
 961 TTTGTGGTTTTTCCCCCTCTTTGGCTGGTGGAGGATAAAGTTCCTGCTCTTTTACCTCCAAGACGAGGGCCTCATTGATT
1041 CACTTCCAGAAGTGCTGCACTTCTGAAGAACAAGGATGCACTAAAGTTAGCAAGTTTATAATAAAGTTAAATATAAATTA
1121 TTTTGTTTTAAAATGCCTCAAATTTTTCTTTATTCTAAGCAGCAAACATTAAAATAAGAATATTTCCTGCTAAATGTAAC
1201 CATACACTTTATTCCACAAAATGTTATTTAACAAGACTGAGGGTTTTTTTTAAGAAAAAATTATTTCCATCCAATATTTA
1281 AAGACTTGAATTTTATTTAAACTTGAAAATGACTTTGCCTTAACTTTTGTATAAGACAGCTTAGAGTCCATGGAGCCCGG
1361 CCCTGGGTTGGCGTGAGTGGGTCAGAGTTACTCAGTTACTGCGTGGATCTCCTGTCGCTAGTTTTACTGAGTAAGCATAC
1441 TGTAGTACAAGAGCTAGTAGTAGTTTTTGTAATATACCTTAAAGATCTTCAACAGTTGATCTTTTTTCAGAATGTTGGAA
1521 AATCCTGTAAATGCAAATAGTCAATACTGTATTAAATACGTGCACTTGGAGTGTGCTTCGCTTGTACAGTTGTAAATAAT
1601 CAGAACATATGAAAAAGGTACCCTACAGAGAAAATTCTGATACAGATTATTGATATATTATAAATGTTGCTGTTGAGCGG
1681 GATGTAGATAAACTAAATGTTGTGGTTTGAATATTATTTTGATTTGTTGAGATTTTCTTTTTTCTCTTACATCGGTGTGT
1761 TGAACTGATTCTGCCTCTTTGCTGCAAAAGGGAATTGGAAAGTCTTATTAAAAGCCTCCAGATGTTTTCATACTCTTTTA
1841 AAATGTATGTAAATGCATACTAATCATATCTAATGTGAAAGAGTTTTAAAGTATATAGAGAGCAAAAACTGGCAGGATCG
1921 TAAGTGAAGGTGACTAGTAATCTAATTTAAATCACCTGCAGCTAAGCATGATTGACCCTGCCAGAGGAAAACATGCCTAT
2001 TTGACCATTTCCTTTAAAGCAGTTGCCATTATTCAAATACAGAGAAATAGCCACAGGGCTAGTGTTTTTCAAATGCATTT
2081 TAAAGAACATGGGGATTTTTTTTTGTAGTTGTCAGTTCACTGACCAAAAAAAAAAAAAAAATCAGAAATAATTGATCTGT
2161 GAAACCCAAACTCTCAATACTCAGAAAGCTGGGAGGCAACCTCGAGGCCTGGGCCTACGAGCTGCATCTTCGCTACGGAA
2241 GGGCCAGGGCGCCATCAGCCATTCCCAAAACACAAGGCCTGCCCGTCCGCCAGTGAGTCCTTGGTTTTTAATAATGAGAA
2321 GTCCTTTCCCCCAAGGTGTGAGCATTGCAGCGCAGTGTGTGTGTGTGGTTAGAGCCAGCTTAGTCCTTCACTTTGTCGAC
2401 CGAAGTGGGAGCTCAACAGCTGCATGAGGAGGGCAGCGCGTGCATTAGCCAGTCGCCACTGGAGGGCTCTGCTGCCCTCC
2481 GGTCAATACACTGTAGTTACTGCCTAGCCAGCAGCAGTCTTCTGCATCAAGAACTGAAACGTTGCTCGGAGGTGATTTTT
2561 ATAGCATCCTTTTTAATTAAAGGTGAAATACAGATTGCTATATAATGTCTGAAAAAACCTGATACTACTTCAAGAGTTTC
2641 TGCTCAGAAGAAAATGAGAGTTATCATAATAGGAAGCTGTGGCGGTCCATGCCAACTGTGCTGTGTCACATACAGCGATG
2721 AGAGTGGCTTTCATACTTTTTTTTTTTTTAAGTTAACACCCTCCTTTACCCCCAGCAGTATCTCAGGTTATAGAATCAGA
2801 GATGCAGCAGTGACAAATGGCATTTTAACTTGTAAAATCGTGTGATGATGCTTATCATTTTGAAATAGAAGAATAAAAAC
2881 CTGGTCCCGTTTCACCAGACATGAATTTCAAGTGGAGTCGTCGTTCTCTGAGAGTGAGTGTCTTGACATTTTCACCCAGG
2961 CCCTCCTGTCATCACATCACCGGCTGTCACTGGCGGGTGGCCGTAAACGTCCTGCGTTGCTATATTAGGATCTCTGCAGT
3041 TCAGGCTTCAAAACCAGTTCAGTGTATCCGGGCGACGGGTAGTGGTGGTGCATGCCTGTCTGTGTGCCCCGCTGGCGAGC
3121 TGTAGTTGCGGCTTGCGTGCCTCGCGGCCCACTACAGGGCTGCAGACAATCGAGGCGAGGGCGCTGGCCGCCAGCAGCTC
3201 ACAGCGCGGGGGTCATGTGGTCGCTCCTCGAGGGTTTCGTTTTTGTTCTGCTTCATTAAGACTGGAATCAAGCTTACATG
3281 TAAACTATTGGTAATTTAAGTTTCCTTTTGTGTCATTCAGTGTAAAACTGTCTAATTTGAAAAAAAATGTAGGTTATGAA
3361 AATAAAGATTTAGGCACTGTTCAATTTTTCTTTTGATTTTTTTTAAATTAAAATTTCTTCAATAATGCATCTTTTCTAAA
3441 CATAGTTTTTTGTCTGTTCCCATAAGTGCATGAGAAAGAAACACGGGCCTCATATATGATTGGATCCTAAAGCCTTCTCA
3521 CCTACGTGGGGGCTGGCTGTGGCACACGGGGCTCACCCTTTGTGTTTTAGTGGTTCAGAGTGAGCATTAACATCAGATGC
3601 TCATGCGGAGACAGCCATTACTGTGACTGCCAAGATGTACTGCAAAAATACATGTTCCTGTATCAGGACTTTGATTTTGT
3681 TAAAATGGCACTCTCTCCAAAGCTGTGTCCATGAAGCTGTTTGGAGCTAACGTTGGGTCTTCATGGTGATGGACTCATCC
3761 TTAGGCAGCAGTGATGTCTGCACTAGGAAGAGGCTGGCGGGAGGCGGGGCCCCTCCTGTGCCAGGCACCGAGTGGATGGG
3841 GGACTGATTAACATGTTGCTGCCTTCCTCCTCTGTGCATTGCCTTTTCATGTCGTCTTCCCATTTTTACTCTTTTTCTGA
3921 TGGAATTAATATTCTTGATCTGTTAAGGCTATTAATCCTTTGTCATATATGTTACAAATATTTTCTTTCAATCTACCATT
4001 TGTCTTAACTCTTTATTTAGAATAGTATCTTTTACGGTGTTTAATTATTGTGTAGTAAAATCTATCAATCTTCTCCTTTG
4081 TTGAGTGTCTTGGACTTGCTTAAGAAGCCTTTCCCTACTCCAGGGTCATAAAGTTAATAGTGTGTGTGTATGTGTGCGTG
4161 TGTGTGTGTGTGTGCGTGCACACGCACACACACACACACACGCTTTTAATCCAGCTGGGCCTAATCGTGTGTGTGGTGTG
4241 CGTGCTTAGGCAGGAACCCAGTTTTACTTTATGCCATGTGGAAAGTTTCTTTTTCCAGTATCACCAGTGAGTTCACTGTC
4321 TCTCCACTGGTCTGCAGTGCTGCTTCTGTTACTTGCAGACTTCCCACGTGTGCATGGATCTCCACCTGGGGTCTCTAGGG
4401 TCTCTATTCTACACTGCCTATTTCCCTTTCTGTCCTAACACCATAGCATTTAACTCACCCGTCATCCTGTGTTGCTGAGA
4481 ATTTCCTTCATAGAACTCATCAAAGTATGATTAACTGTGCTCCCTGAGGGCAGGAATTATGCCATCTGGATCACCAGCCT
4561 CTCCCTTGTCCTTAGCACGCCATCTGCAAATTAGCAGATACTCGGTAAATGTGTATTAACTCGAAGTATATTTTGTGTCT
4641 TCTCTGTGCACAGCACTGCCCTGGGAAGAACTAGGATGAGGTATTGACTTGCTGTTGCCACATAACAAACCCTGCCAGAA
4721 CTCCCTGGATGGAAGTGACCACCGTGTATCTGTGGATTGTCTGCAGGGCTCTGCTGGGGTCAGCAGGTCCCACAAGAGAG
4801 CCAGGGCTCGGTCTCCTCATGGCTGTCAGAGGTTTACGTATTCCGCCTCCACCCACCAAAGTCTGAAGTTGTTGTATTCC
4881 ATTCCTTGCTATATCCACATCTTTTAATAATGCTAAAATCCCGTGTTTCTCTAAAGCATTGGATTGAACCAACTGAAGAA
4961 GGACCACGTGTGTTGCTGGGCCTGCTTGGGCACAAGCCGTTTCCGATCCAAGTCAACTGCTGGTCTGCTTAGACGAAGGT
5041 GTGTGGGTGTCTCCACCACGGAGAGGAGGGACAGCAGGTGAGACCATAGGCCAGGAAGGAAGGGCACAGCCTAAGCGTGC
5121 AGTGGCTTAGCCAGAGACCCTCGTGCACCAGCCTTCAGGTGCTTATGGAACTTATGTCAGCCCAGGCCATATCCAAGTGT
5201 GTGATGTCTCGGAGCATATATGCCAGGCCAGCCGGAGAGGCTTAGCCCTGCCCTGGTGGAGCTGGAGGGCCGCAGGGCCG
5281 CCCGGTGGGGTCAGGAGGTTGTGAAGAGGATCCTGATACAGGCTGGGCCTCCCTGCAGGCGTGAGCCCCGGAGCACGGGG
5361 TGAGCAGCTCCACCCAGAGGGGCTTGCAGGACCAAGCTGGGACAGCAACCACCAGGCCCTGGGGCAGATCAGTGAGCGTC
5441 CAGGAGATGCAGATGCAGAAGACAGCCAAATTCATTCACCTCTGCGTGGGCCTGTGAGGGCCCACAGAGATGCATTTTCA
5521 TTCACGACCAGGATTTCCTCGGCCGGAGCAGCCGCTTTTCCCAGCCGAAGCTCACTGTGTTTACTACATAGGATGTGAGT
5601 GTATAGAAAGACTCTCTCTAACGTTAGCTACGCGTGCAGAAATGTGGGGCGCTTACAAGTGTGGGCAGCCGCAGCCTGTT
5681 CCTCACCCCTGTCCTAACGGGACATACTCCACGCATGCACATTTAGGATCACCGTGTCTTCTCGTTGGACTGATCTGTCA
5761 TTAGGACCCTGGACCCAAGTAATTGTCTTTGCTCTGAAGTTTTGACAGTAACAAAGGCATTCCAGCTCTTTCTTTTTCAC
5841 TCCTGTCGGTGTAACGTGCCGTTTTTCATCCTTTGACTTTTAGCCCGCCTGTGCCCTGTCTGAAGGGAGTTGTCTGTGGA
5921 CAGCACGGAGTGGTGGGTGTTTGTAATCCACTCTGCCAGCCTCAGTCTTCTAACTGTTGCGTATGGACCAATTACATCTG
6001 CCCTTTCTCTTC
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uugauacgUUGG---AUGAUGGAGa 5'
                  ||||   ||||||:|| 
Target 5' tctgaaaaAACCTGATACTACTTCa 3'
 2608 - 2632 142.00 -13.80
2 
miRNA  3' uugAUACG--UUGG--AUGAUGGAGa 5'
             |:||:  |||:  | ||:|||| 
Target 5' cggTGTGTTGAACTGATTCTGCCTCt 3'
 1753 - 1778 139.00 -15.10
3 
miRNA  3' uugauACGUUGGAUGAUGGAGa 5'
               |||  :|| :|||||| 
Target 5' gttccTGC--TCTTTTACCTCc 3'
 1000 - 1019 137.00 -12.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30113902 6 COSMIC
COSN30116955 6 COSMIC
COSN21982524 15 COSMIC
COSN30499412 24 COSMIC
COSN31501833 27 COSMIC
COSN30450235 31 COSMIC
COSN30192941 50 COSMIC
COSN30152153 65 COSMIC
COSN28843128 70 COSMIC
COSN31494801 86 COSMIC
COSN31518084 163 COSMIC
COSN17075698 193 COSMIC
COSN31575834 245 COSMIC
COSN31603316 246 COSMIC
COSN21317294 264 COSMIC
COSN31569845 270 COSMIC
COSN17902350 325 COSMIC
COSN15661718 366 COSMIC
COSN19657777 367 COSMIC
COSN29019618 368 COSMIC
COSN16284154 472 COSMIC
COSN28399723 692 COSMIC
COSN26565573 727 COSMIC
COSN24680304 752 COSMIC
COSN28650551 844 COSMIC
COSN30542486 888 COSMIC
COSN24719556 972 COSMIC
COSN31609003 1025 COSMIC
COSN21934337 1075 COSMIC
COSN29432549 1091 COSMIC
COSN31563408 1155 COSMIC
COSN31592821 1243 COSMIC
COSN21293759 1303 COSMIC
COSN26563390 1318 COSMIC
COSN31608406 1485 COSMIC
COSN19377664 1535 COSMIC
COSN31610801 1545 COSMIC
COSN1504249 1638 COSMIC
COSN31547630 1687 COSMIC
COSN30540438 1754 COSMIC
COSN5886875 2085 COSMIC
COSN27465519 2126 COSMIC
COSN30005228 2141 COSMIC
COSN21698415 2177 COSMIC
COSN31959510 2203 COSMIC
COSN10074042 2234 COSMIC
COSN4695410 2593 COSMIC
COSN29484581 2663 COSMIC
COSN27315346 2737 COSMIC
COSN25478435 2754 COSMIC
COSN25484887 2766 COSMIC
COSN31545368 3069 COSMIC
COSN8640580 3151 COSMIC
COSN26480563 3271 COSMIC
rs9124 844 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs202103534 4 dbSNP
rs372671338 5 dbSNP
rs1408188382 6 dbSNP
rs766553624 7 dbSNP
rs760903927 8 dbSNP
rs369034490 9 dbSNP
rs1488595101 10 dbSNP
rs1187300171 15 dbSNP
rs767645088 18 dbSNP
rs1192789626 19 dbSNP
rs761712085 22 dbSNP
rs762762869 23 dbSNP
rs375294911 24 dbSNP
rs375228225 30 dbSNP
rs200155088 31 dbSNP
rs758405099 32 dbSNP
rs956028179 33 dbSNP
rs1419645675 34 dbSNP
rs1296825553 38 dbSNP
rs986228945 44 dbSNP
rs746529293 45 dbSNP
rs1222192912 46 dbSNP
rs369739919 48 dbSNP
rs144868339 49 dbSNP
rs755071641 49 dbSNP
rs1377951032 54 dbSNP
rs1009375417 56 dbSNP
rs1243273008 58 dbSNP
rs570638590 59 dbSNP
rs879742470 63 dbSNP
rs1201052302 70 dbSNP
rs1003628506 71 dbSNP
rs199858821 76 dbSNP
rs1479461469 77 dbSNP
rs1237156871 78 dbSNP
rs1231801476 81 dbSNP
rs1381016230 82 dbSNP
rs559713818 82 dbSNP
rs1157450914 83 dbSNP
rs1404965414 86 dbSNP
rs1415444868 96 dbSNP
rs533860961 99 dbSNP
rs1357736555 104 dbSNP
rs1450032380 112 dbSNP
rs752758889 113 dbSNP
rs368748710 120 dbSNP
rs1310914762 124 dbSNP
rs1007330176 125 dbSNP
rs188031987 126 dbSNP
rs1222846287 128 dbSNP
rs1277756069 134 dbSNP
rs1323936465 141 dbSNP
rs1284978377 144 dbSNP
rs1346994408 145 dbSNP
rs1219693587 148 dbSNP
rs1045258289 158 dbSNP
rs1226785333 161 dbSNP
rs1459765117 164 dbSNP
rs1005283789 170 dbSNP
rs1200762441 171 dbSNP
rs56215024 172 dbSNP
rs891139879 172 dbSNP
rs768707171 173 dbSNP
rs145677703 174 dbSNP
rs1478656149 176 dbSNP
rs1172446016 181 dbSNP
rs1423516957 183 dbSNP
rs563584409 192 dbSNP
rs765854340 193 dbSNP
rs2892160 195 dbSNP
rs550258389 204 dbSNP
rs1467511197 214 dbSNP
rs1049236092 216 dbSNP
rs930077727 235 dbSNP
rs1481111870 236 dbSNP
rs1400548696 239 dbSNP
rs868085350 240 dbSNP
rs897309345 241 dbSNP
rs919517189 250 dbSNP
rs1332267693 256 dbSNP
rs565059369 256 dbSNP
rs74115585 257 dbSNP
rs1321241471 258 dbSNP
rs1336603648 262 dbSNP
rs1202646981 271 dbSNP
rs944742050 284 dbSNP
rs910533895 287 dbSNP
rs1194252108 292 dbSNP
rs980363947 293 dbSNP
rs1452184886 297 dbSNP
rs563522995 305 dbSNP
rs986647166 306 dbSNP
rs760078407 310 dbSNP
rs1470592129 311 dbSNP
rs915307189 318 dbSNP
rs1479036665 323 dbSNP
rs1171797276 324 dbSNP
rs17159943 325 dbSNP
rs766630236 338 dbSNP
rs988932274 345 dbSNP
rs1392263553 350 dbSNP
rs1157478799 353 dbSNP
rs1416935317 356 dbSNP
rs955848289 357 dbSNP
rs1343538647 361 dbSNP
rs1401725795 363 dbSNP
rs1392392591 367 dbSNP
rs1225525670 368 dbSNP
rs1339536064 368 dbSNP
rs956494097 368 dbSNP
rs1323907994 369 dbSNP
rs1470850127 383 dbSNP
rs371838932 384 dbSNP
rs1164402577 385 dbSNP
rs1209297227 385 dbSNP
rs1274136923 385 dbSNP
rs58718835 385 dbSNP
rs74828159 385 dbSNP
rs879107294 385 dbSNP
rs1240756620 386 dbSNP
rs1369824484 387 dbSNP
rs1202877400 391 dbSNP
rs1458011725 391 dbSNP
rs1461761501 398 dbSNP
rs78608705 402 dbSNP
rs1034969974 403 dbSNP
rs978588601 405 dbSNP
rs1003459590 406 dbSNP
rs1341264320 412 dbSNP
rs572811759 414 dbSNP
rs1023288189 415 dbSNP
rs761584284 418 dbSNP
rs1225716215 419 dbSNP
rs1376982677 421 dbSNP
rs562383747 424 dbSNP
rs76896344 425 dbSNP
rs1485130293 427 dbSNP
rs55921400 428 dbSNP
rs1453974802 430 dbSNP
rs575994548 433 dbSNP
rs1424061295 436 dbSNP
rs1182539622 459 dbSNP
rs1382859002 462 dbSNP
rs1008832582 463 dbSNP
rs1235683105 464 dbSNP
rs1318916803 470 dbSNP
rs147517439 471 dbSNP
rs7703 472 dbSNP
rs1451412073 478 dbSNP
rs993658568 481 dbSNP
rs144806278 482 dbSNP
rs55861321 489 dbSNP
rs573391637 490 dbSNP
rs368006313 491 dbSNP
rs1315622974 492 dbSNP
rs779971222 504 dbSNP
rs1256967500 509 dbSNP
rs1445138909 518 dbSNP
rs946662599 523 dbSNP
rs906049415 526 dbSNP
rs1202715546 530 dbSNP
rs567984723 537 dbSNP
rs190026923 538 dbSNP
rs1406563586 544 dbSNP
rs1485399726 546 dbSNP
rs535441144 553 dbSNP
rs185518642 561 dbSNP
rs375396945 566 dbSNP
rs570072537 568 dbSNP
rs1290958361 573 dbSNP
rs916891893 574 dbSNP
rs766622512 575 dbSNP
rs927766034 575 dbSNP
rs546364994 576 dbSNP
rs978492152 577 dbSNP
rs969349713 581 dbSNP
rs964488316 587 dbSNP
rs769951770 593 dbSNP
rs1017392786 595 dbSNP
rs983811653 598 dbSNP
rs150639670 599 dbSNP
rs559734981 611 dbSNP
rs571042910 612 dbSNP
rs1222046180 618 dbSNP
rs547977444 619 dbSNP
rs527912314 621 dbSNP
rs1363004741 624 dbSNP
rs1319602227 627 dbSNP
rs1291009811 633 dbSNP
rs1198836451 634 dbSNP
rs370683351 641 dbSNP
rs17293531 659 dbSNP
rs774929589 673 dbSNP
rs1192916499 683 dbSNP
rs1363378456 689 dbSNP
rs117349341 691 dbSNP
rs1424693975 692 dbSNP
rs1005641952 693 dbSNP
rs1425454258 699 dbSNP
rs1466356749 709 dbSNP
rs1352904899 713 dbSNP
rs531202688 715 dbSNP
rs1459499139 721 dbSNP
rs1294681706 723 dbSNP
rs557673381 731 dbSNP
rs1280519782 739 dbSNP
rs1341460292 748 dbSNP
rs889379904 749 dbSNP
rs1051084685 751 dbSNP
rs946736364 754 dbSNP
rs893808764 759 dbSNP
rs1223095461 760 dbSNP
rs1266002128 769 dbSNP
rs1490174584 773 dbSNP
rs896093513 777 dbSNP
rs1265077733 787 dbSNP
rs181401650 798 dbSNP
rs1186207058 801 dbSNP
rs934296890 816 dbSNP
rs778170306 817 dbSNP
rs544316770 822 dbSNP
rs576836085 822 dbSNP
rs935390194 826 dbSNP
rs928011168 827 dbSNP
rs1300512295 831 dbSNP
rs11253452 833 dbSNP
rs577841444 840 dbSNP
rs1359387413 843 dbSNP
rs9124 844 dbSNP
rs1358032224 846 dbSNP
rs910384625 852 dbSNP
rs1288059962 855 dbSNP
rs1447415702 859 dbSNP
rs574301387 862 dbSNP
rs1214770967 864 dbSNP
rs1227259713 871 dbSNP
rs191432904 872 dbSNP
rs983998669 884 dbSNP
rs1182610717 887 dbSNP
rs1384696308 888 dbSNP
rs952403112 890 dbSNP
rs1161031309 891 dbSNP
rs954776734 894 dbSNP
rs1316719113 901 dbSNP
rs1361210563 907 dbSNP
rs1025250388 909 dbSNP
rs972341964 910 dbSNP
rs972409734 912 dbSNP
rs1243110064 916 dbSNP
rs765765251 924 dbSNP
rs538186208 939 dbSNP
rs760253460 940 dbSNP
rs141866145 946 dbSNP
rs1296004883 947 dbSNP
rs1016955875 949 dbSNP
rs2386869 953 dbSNP
rs1204619344 955 dbSNP
rs187040533 958 dbSNP
rs1242741440 967 dbSNP
rs747324029 971 dbSNP
rs1009077425 972 dbSNP
rs749986012 978 dbSNP
rs1415558945 981 dbSNP
rs767203088 993 dbSNP
rs1011145063 994 dbSNP
rs1470093247 997 dbSNP
rs1023534966 1007 dbSNP
rs893841445 1024 dbSNP
rs1052449728 1025 dbSNP
rs999486771 1044 dbSNP
rs906625376 1046 dbSNP
rs1449966192 1072 dbSNP
rs1046908957 1077 dbSNP
rs1332820604 1080 dbSNP
rs947952322 1083 dbSNP
rs1335777457 1100 dbSNP
rs1490904559 1102 dbSNP
rs1277703825 1115 dbSNP
rs1248487307 1137 dbSNP
rs1223870701 1138 dbSNP
rs1262794602 1144 dbSNP
rs916379477 1156 dbSNP
rs1321708519 1164 dbSNP
rs1048326170 1174 dbSNP
rs895985297 1188 dbSNP
rs931240820 1190 dbSNP
rs1251350347 1195 dbSNP
rs1053348766 1197 dbSNP
rs1481235692 1205 dbSNP
rs1248942551 1207 dbSNP
rs1253549792 1211 dbSNP
rs1222260273 1237 dbSNP
rs1323193463 1241 dbSNP
rs1467919544 1252 dbSNP
rs999062889 1252 dbSNP
rs904161719 1257 dbSNP
rs918477952 1259 dbSNP
rs1326826369 1261 dbSNP
rs1332723576 1267 dbSNP
rs1223732358 1272 dbSNP
rs558689465 1274 dbSNP
rs1332528533 1286 dbSNP
rs965383983 1287 dbSNP
rs1042735832 1290 dbSNP
rs943105880 1294 dbSNP
rs1220700409 1309 dbSNP
rs1252105273 1311 dbSNP
rs1419782598 1331 dbSNP
rs777863265 1340 dbSNP
rs1390364045 1342 dbSNP
rs1194121158 1350 dbSNP
rs1292067234 1351 dbSNP
rs761621860 1352 dbSNP
rs985613765 1356 dbSNP
rs910332620 1358 dbSNP
rs1479007041 1359 dbSNP
rs1194962498 1360 dbSNP
rs539466180 1373 dbSNP
rs774270751 1375 dbSNP
rs570930728 1379 dbSNP
rs1366838557 1382 dbSNP
rs764027279 1383 dbSNP
rs1481525744 1393 dbSNP
rs1362332737 1398 dbSNP
rs953595095 1401 dbSNP
rs1181391107 1402 dbSNP
rs971941114 1403 dbSNP
rs547915835 1405 dbSNP
rs1202270559 1406 dbSNP
rs1286044365 1407 dbSNP
rs1011051593 1408 dbSNP
rs1264138086 1409 dbSNP
rs527848786 1411 dbSNP
rs984145084 1412 dbSNP
rs1206052458 1415 dbSNP
rs958295637 1416 dbSNP
rs1031223327 1417 dbSNP
rs1446085334 1427 dbSNP
rs1190502634 1432 dbSNP
rs1277356764 1433 dbSNP
rs1063498 1434 dbSNP
rs1237915831 1437 dbSNP
rs1162915479 1442 dbSNP
rs999560343 1446 dbSNP
rs1455248712 1453 dbSNP
rs1310826974 1469 dbSNP
rs906524506 1469 dbSNP
rs1046496866 1474 dbSNP
rs568713885 1477 dbSNP
rs1450335493 1485 dbSNP
rs1380752366 1496 dbSNP
rs1023020042 1500 dbSNP
rs1336399929 1509 dbSNP
rs1012730567 1513 dbSNP
rs1245316753 1514 dbSNP
rs1313598779 1515 dbSNP
rs1356501259 1518 dbSNP
rs1240324004 1531 dbSNP
rs895200907 1536 dbSNP
rs1337127376 1542 dbSNP
rs1348900410 1548 dbSNP
rs1203077609 1552 dbSNP
rs1244583507 1554 dbSNP
rs1048233335 1559 dbSNP
rs1182479826 1560 dbSNP
rs1240676611 1568 dbSNP
rs1415916255 1572 dbSNP
rs1420822866 1575 dbSNP
rs1382553271 1576 dbSNP
rs1014770142 1577 dbSNP
rs148090139 1579 dbSNP
rs181825779 1580 dbSNP
rs1178909640 1582 dbSNP
rs769706806 1589 dbSNP
rs999053028 1597 dbSNP
rs1175716296 1598 dbSNP
rs1452143351 1617 dbSNP
rs745968296 1618 dbSNP
rs1375553929 1628 dbSNP
rs1392486528 1633 dbSNP
rs1306911700 1634 dbSNP
rs386739778 1637 dbSNP
rs1444532478 1643 dbSNP
rs1315565872 1646 dbSNP
rs1021233879 1660 dbSNP
rs1007154227 1666 dbSNP
rs1323836333 1672 dbSNP
rs776645064 1678 dbSNP
rs771130077 1679 dbSNP
rs1445597554 1688 dbSNP
rs539126583 1690 dbSNP
rs1051485685 1694 dbSNP
rs1249700619 1695 dbSNP
rs1417118395 1705 dbSNP
rs11816921 1715 dbSNP
rs756475199 1718 dbSNP
rs1469497501 1727 dbSNP
rs1036237420 1739 dbSNP
rs1287530981 1750 dbSNP
rs778082233 1751 dbSNP
rs1298155572 1753 dbSNP
rs1358139781 1755 dbSNP
rs1371771169 1771 dbSNP
rs1407241993 1775 dbSNP
rs1284340475 1785 dbSNP
rs953943701 1792 dbSNP
rs1222593271 1797 dbSNP
rs545754876 1802 dbSNP
rs980696341 1804 dbSNP
rs1204564377 1812 dbSNP
rs531983458 1821 dbSNP
rs1450137420 1825 dbSNP
rs1479632437 1830 dbSNP
rs1224559992 1831 dbSNP
rs1269341191 1836 dbSNP
rs1479986670 1838 dbSNP
rs375507274 1840 dbSNP
rs1421889909 1845 dbSNP
rs1317451579 1861 dbSNP
rs915898578 1866 dbSNP
rs1352778769 1868 dbSNP
rs559774507 1875 dbSNP
rs1382987418 1876 dbSNP
rs1403465610 1881 dbSNP
rs538975451 1895 dbSNP
rs1272756403 1896 dbSNP
rs1363671698 1898 dbSNP
rs1031296571 1904 dbSNP
rs1294254604 1911 dbSNP
rs752848685 1918 dbSNP
rs11539831 1919 dbSNP
rs41305671 1920 dbSNP
rs1490139505 1927 dbSNP
rs1007770976 1931 dbSNP
rs1012223702 1934 dbSNP
rs895221882 1936 dbSNP
rs888753778 1940 dbSNP
rs1243594065 1944 dbSNP
rs1030445971 1946 dbSNP
rs1486324189 1946 dbSNP
rs4229 1948 dbSNP
rs1446506185 1951 dbSNP
rs41306306 1960 dbSNP
rs1036183396 1966 dbSNP
rs1423241891 1970 dbSNP
rs1320713671 1974 dbSNP
rs1346102953 1976 dbSNP
rs138109726 1977 dbSNP
rs1036935085 1980 dbSNP
rs1362478207 1981 dbSNP
rs558601324 1998 dbSNP
rs539775453 1999 dbSNP
rs11539832 2006 dbSNP
rs1315693262 2008 dbSNP
rs570871082 2021 dbSNP
rs1044961764 2040 dbSNP
rs1447181322 2050 dbSNP
rs947971652 2051 dbSNP
rs1317287899 2062 dbSNP
rs1215406600 2081 dbSNP
rs1246398029 2087 dbSNP
rs1264824202 2090 dbSNP
rs1184318811 2095 dbSNP
rs1242555083 2096 dbSNP
rs1443345888 2096 dbSNP
rs1219840235 2100 dbSNP
rs915904715 2104 dbSNP
rs1400480520 2105 dbSNP
rs993276400 2105 dbSNP
rs1358028212 2106 dbSNP
rs1291891524 2107 dbSNP
rs1229947921 2108 dbSNP
rs1337445315 2111 dbSNP
rs564168819 2113 dbSNP
rs1269348609 2120 dbSNP
rs796134067 2121 dbSNP
rs1227948908 2122 dbSNP
rs1271989666 2125 dbSNP
rs938768017 2126 dbSNP
rs1301482516 2140 dbSNP
rs1209982608 2142 dbSNP
rs1336845708 2142 dbSNP
rs1381318262 2142 dbSNP
rs201849569 2142 dbSNP
rs34933454 2142 dbSNP
rs537720580 2142 dbSNP
rs1404573224 2144 dbSNP
rs1262598962 2147 dbSNP
rs1366206238 2149 dbSNP
rs554301483 2154 dbSNP
rs1325674442 2160 dbSNP
rs891017109 2173 dbSNP
rs1175880751 2175 dbSNP
rs1419470945 2176 dbSNP
rs1470754312 2178 dbSNP
rs977496554 2179 dbSNP
rs145492562 2183 dbSNP
rs1049880298 2189 dbSNP
rs932297515 2191 dbSNP
rs1412240247 2192 dbSNP
rs1478985876 2199 dbSNP
rs1355070194 2200 dbSNP
rs1021756432 2203 dbSNP
rs1286236367 2207 dbSNP
rs568650702 2209 dbSNP
rs1490101383 2211 dbSNP
rs1246778001 2215 dbSNP
rs989895426 2218 dbSNP
rs548725788 2219 dbSNP
rs1197599357 2221 dbSNP
rs924089926 2224 dbSNP
rs1435987836 2226 dbSNP
rs978253531 2231 dbSNP
rs1029980739 2232 dbSNP
rs971403963 2233 dbSNP
rs961750258 2235 dbSNP
rs1014657893 2236 dbSNP
rs538074932 2237 dbSNP
rs1281155623 2238 dbSNP
rs1005977308 2241 dbSNP
rs1025183996 2250 dbSNP
rs991237022 2251 dbSNP
rs959360211 2252 dbSNP
rs1044950574 2254 dbSNP
rs1302822184 2258 dbSNP
rs1329598846 2259 dbSNP
rs1223116175 2272 dbSNP
rs1270860207 2281 dbSNP
rs569485569 2284 dbSNP
rs756945429 2285 dbSNP
rs897022265 2288 dbSNP
rs148874427 2289 dbSNP
rs531971224 2296 dbSNP
rs1265646479 2298 dbSNP
rs1330066006 2303 dbSNP
rs189254186 2311 dbSNP
rs1404351433 2312 dbSNP
rs891041180 2314 dbSNP
rs924619138 2321 dbSNP
rs138556614 2324 dbSNP
rs1386983527 2328 dbSNP
rs1425492803 2328 dbSNP
rs1425179938 2329 dbSNP
rs1050358 2330 dbSNP
rs1063500 2331 dbSNP
rs932347866 2334 dbSNP
rs947509290 2347 dbSNP
rs1388238432 2351 dbSNP
rs892788133 2352 dbSNP
rs1192593091 2355 dbSNP
rs1468121021 2364 dbSNP
rs986728550 2365 dbSNP
rs1432949240 2368 dbSNP
rs370015613 2368 dbSNP
rs1054235803 2378 dbSNP
rs763935481 2381 dbSNP
rs529773577 2398 dbSNP
rs1353277842 2400 dbSNP
rs953643181 2401 dbSNP
rs560835872 2402 dbSNP
rs544368251 2404 dbSNP
rs961666861 2405 dbSNP
rs1445180743 2411 dbSNP
rs1014604220 2415 dbSNP
rs1366559662 2416 dbSNP
rs1455131909 2428 dbSNP
rs1005964309 2429 dbSNP
rs1388216814 2430 dbSNP
rs1222289753 2431 dbSNP
rs766829231 2433 dbSNP
rs1338792826 2434 dbSNP
rs575354061 2437 dbSNP
rs1452628993 2438 dbSNP
rs1311196298 2440 dbSNP
rs530815261 2445 dbSNP
rs1240172079 2446 dbSNP
rs545017252 2447 dbSNP
rs1449646660 2452 dbSNP
rs79045717 2454 dbSNP
rs918199266 2455 dbSNP
rs1328075066 2457 dbSNP
rs1012466817 2459 dbSNP
rs1206376836 2459 dbSNP
rs896340235 2460 dbSNP
rs1181257666 2463 dbSNP
rs759451125 2465 dbSNP
rs776750269 2466 dbSNP
rs1026929634 2471 dbSNP
rs1471733752 2475 dbSNP
rs771042075 2480 dbSNP
rs78496140 2481 dbSNP
rs1406589893 2483 dbSNP
rs1301650521 2492 dbSNP
rs1399302547 2495 dbSNP
rs1178781923 2500 dbSNP
rs750737938 2503 dbSNP
rs1288132593 2514 dbSNP
rs1348948043 2519 dbSNP
rs1226266436 2524 dbSNP
rs1284779090 2530 dbSNP
rs10795298 2541 dbSNP
rs1241250028 2547 dbSNP
rs1208855668 2548 dbSNP
rs1050544531 2553 dbSNP
rs1481581567 2560 dbSNP
rs932117778 2561 dbSNP
rs1250884729 2565 dbSNP
rs1481940963 2571 dbSNP
rs1201930667 2581 dbSNP
rs1008488019 2583 dbSNP
rs923465998 2589 dbSNP
rs1454198602 2600 dbSNP
rs1174076901 2601 dbSNP
rs955230599 2602 dbSNP
rs976705971 2604 dbSNP
rs1462949162 2605 dbSNP
rs1347045780 2606 dbSNP
rs773444443 2607 dbSNP
rs1483418514 2609 dbSNP
rs1307958914 2610 dbSNP
rs1369158489 2618 dbSNP
rs532272283 2618 dbSNP
rs796842787 2630 dbSNP
rs1239004755 2633 dbSNP
rs1028680793 2635 dbSNP
rs1213896896 2643 dbSNP
rs1316626439 2645 dbSNP
rs1286789971 2650 dbSNP
rs996751372 2656 dbSNP
rs373138421 2664 dbSNP
rs1228135879 2666 dbSNP
rs369673200 2682 dbSNP
rs998482690 2683 dbSNP
rs902941661 2684 dbSNP
rs1045479920 2713 dbSNP
rs1357402786 2715 dbSNP
rs1488288500 2716 dbSNP
rs544265975 2720 dbSNP
rs145650239 2725 dbSNP
rs1264032610 2730 dbSNP
rs538393259 2736 dbSNP
rs1453989641 2737 dbSNP
rs918074219 2738 dbSNP
rs1291414765 2750 dbSNP
rs1349589441 2750 dbSNP
rs1388892812 2750 dbSNP
rs528623709 2750 dbSNP
rs1381721407 2751 dbSNP
rs960790997 2757 dbSNP
rs1363511589 2759 dbSNP
rs1435155093 2760 dbSNP
rs1296178143 2761 dbSNP
rs1340004568 2767 dbSNP
rs1248011421 2769 dbSNP
rs1290335338 2770 dbSNP
rs1320885369 2784 dbSNP
rs1034897143 2787 dbSNP
rs184876726 2798 dbSNP
rs1486293137 2804 dbSNP
rs902463678 2810 dbSNP
rs1188029099 2812 dbSNP
rs938281380 2821 dbSNP
rs559777588 2826 dbSNP
rs1158699644 2834 dbSNP
rs1020229423 2839 dbSNP
rs1413593056 2842 dbSNP
rs1420930476 2851 dbSNP
rs1011504894 2852 dbSNP
rs1162790656 2858 dbSNP
rs113034364 2867 dbSNP
rs1050900928 2882 dbSNP
rs974049737 2887 dbSNP
rs538974658 2888 dbSNP
rs1454578634 2889 dbSNP
rs932092677 2897 dbSNP
rs1378235495 2900 dbSNP
rs961327570 2903 dbSNP
rs1184604223 2909 dbSNP
rs1286024291 2911 dbSNP
rs1485652665 2912 dbSNP
rs1330098908 2915 dbSNP
rs908658847 2920 dbSNP
rs1266383512 2922 dbSNP
rs902001511 2923 dbSNP
rs566116179 2925 dbSNP
rs1472074670 2934 dbSNP
rs1225660792 2938 dbSNP
rs955411668 2939 dbSNP
rs1489860519 2942 dbSNP
rs575802020 2945 dbSNP
rs1409106933 2947 dbSNP
rs1040584341 2957 dbSNP
rs1246147337 2958 dbSNP
rs1157955617 2959 dbSNP
rs1028168405 2961 dbSNP
rs1385879531 2969 dbSNP
rs546154354 2972 dbSNP
rs1334797105 2974 dbSNP
rs996658395 2981 dbSNP
rs908152197 2982 dbSNP
rs957276073 2986 dbSNP
rs529663321 2992 dbSNP
rs998554768 2993 dbSNP
rs930258200 2994 dbSNP
rs1286654619 2995 dbSNP
rs1049307036 2998 dbSNP
rs1325801455 3002 dbSNP
rs902847750 3003 dbSNP
rs1045914436 3008 dbSNP
rs1441209794 3009 dbSNP
rs1207163537 3015 dbSNP
rs763673717 3016 dbSNP
rs894187115 3026 dbSNP
rs1409274644 3032 dbSNP
rs1481184607 3040 dbSNP
rs1363158405 3045 dbSNP
rs375149979 3060 dbSNP
rs1423775111 3061 dbSNP
rs1035247810 3064 dbSNP
rs372965838 3070 dbSNP
rs140759125 3073 dbSNP
rs550414561 3074 dbSNP
rs1305907544 3076 dbSNP
rs879183093 3077 dbSNP
rs748550193 3083 dbSNP
rs940046626 3088 dbSNP
rs1010780436 3091 dbSNP
rs530724975 3094 dbSNP
rs908524896 3102 dbSNP
rs987174798 3110 dbSNP
rs1427662172 3111 dbSNP
rs955499438 3116 dbSNP
rs1196039724 3117 dbSNP
rs1203492761 3119 dbSNP
rs1271421475 3121 dbSNP
rs996659156 3122 dbSNP
rs1268263246 3129 dbSNP
rs921308665 3129 dbSNP
rs1170452351 3130 dbSNP
rs975251100 3132 dbSNP
rs957183780 3136 dbSNP
rs1040549655 3137 dbSNP
rs1032969207 3143 dbSNP
rs977318397 3144 dbSNP
rs886611344 3145 dbSNP
rs967478027 3146 dbSNP
rs1365132745 3152 dbSNP
rs1226746463 3154 dbSNP
rs1318968995 3159 dbSNP
rs1280559183 3162 dbSNP
rs1049308510 3164 dbSNP
rs1220087061 3169 dbSNP
rs564982471 3171 dbSNP
rs180688592 3172 dbSNP
rs894230582 3176 dbSNP
rs977830400 3177 dbSNP
rs1186594250 3179 dbSNP
rs966475730 3182 dbSNP
rs915081707 3183 dbSNP
rs1386799307 3184 dbSNP
rs1034028092 3189 dbSNP
rs1002362582 3190 dbSNP
rs1392299281 3197 dbSNP
rs779211709 3205 dbSNP
rs573138384 3206 dbSNP
rs542888122 3207 dbSNP
rs752793681 3208 dbSNP
rs74115581 3212 dbSNP
rs762555158 3216 dbSNP
rs887332055 3219 dbSNP
rs574748751 3223 dbSNP
rs1019002171 3229 dbSNP
rs775023346 3230 dbSNP
rs555037175 3238 dbSNP
rs975491519 3239 dbSNP
rs1434937573 3245 dbSNP
rs1160162962 3246 dbSNP
rs1388061049 3247 dbSNP
rs184614068 3248 dbSNP
rs1403564214 3250 dbSNP
rs1395896275 3260 dbSNP
rs780814888 3262 dbSNP
rs1332617153 3263 dbSNP
rs1177125661 3269 dbSNP
rs1055800698 3279 dbSNP
rs939008489 3282 dbSNP
rs1458660368 3301 dbSNP
rs9377 3304 dbSNP
rs925764215 3305 dbSNP
rs35401034 3306 dbSNP
rs575771398 3306 dbSNP
rs927634538 3319 dbSNP
rs977224496 3321 dbSNP
rs1226074716 3325 dbSNP
rs1257196292 3328 dbSNP
rs1483546231 3328 dbSNP
rs1199798430 3330 dbSNP
rs1253883891 3332 dbSNP
rs759527624 3334 dbSNP
rs1183208634 3344 dbSNP
rs563996576 3348 dbSNP
rs945160305 3348 dbSNP
rs1178339532 3349 dbSNP
rs1378207041 3349 dbSNP
rs192956857 3352 dbSNP
rs1466038876 3364 dbSNP
rs1171323941 3369 dbSNP
rs1364955014 3371 dbSNP
rs915071573 3374 dbSNP
rs1202229800 3375 dbSNP
rs1307770003 3378 dbSNP
rs1349522790 3379 dbSNP
rs1389267052 3384 dbSNP
rs188098576 3394 dbSNP
rs1232500921 3395 dbSNP
rs749663570 3397 dbSNP
rs967339718 3397 dbSNP
rs1205635119 3398 dbSNP
rs1024606040 3404 dbSNP
rs1482198734 3405 dbSNP
rs921161815 3405 dbSNP
rs992517326 3405 dbSNP
rs966038898 3410 dbSNP
rs1174624361 3415 dbSNP
rs958609719 3417 dbSNP
rs1392608426 3424 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
BRCA 0.289 0 0.270 0.01 84 Click to see details
STAD 0.442 0.01 0.482 0 32 Click to see details
BLCA 0.528 0.01 0.437 0.03 18 Click to see details
KICH -0.279 0.09 -0.225 0.14 25 Click to see details
LIHC 0.186 0.1 0.197 0.09 49 Click to see details
PRAD 0.175 0.11 0.141 0.16 50 Click to see details
PAAD 0.751 0.12 0.800 0.1 4 Click to see details
ESCA 0.298 0.19 0.245 0.23 11 Click to see details
LUAD -0.25 0.22 -0.301 0.17 12 Click to see details
THCA 0.093 0.24 0.134 0.16 59 Click to see details
PCPG 0.635 0.28 0.500 0.33 3 Click to see details
KIRP 0.098 0.3 0.063 0.37 32 Click to see details
LUSC 0.075 0.33 0.024 0.44 38 Click to see details
CHOL -0.172 0.33 0.083 0.42 9 Click to see details
UCEC 0.08 0.37 0.160 0.26 19 Click to see details
CESC -0.328 0.39 -0.500 0.33 3 Click to see details
COAD -0.092 0.41 0.190 0.33 8 Click to see details
KIRC -0.026 0.42 -0.022 0.43 68 Click to see details
HNSC -0.026 0.44 -0.017 0.46 42 Click to see details
HNSC -0.026 0.44 -0.017 0.46 42 Click to see details
HNSC -0.026 0.44 -0.017 0.46 42 Click to see details
370 hsa-let-7d-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT000401 BDNF brain derived neurotrophic factor 1 1
MIRT000402 CDK6 cyclin dependent kinase 6 1 1
MIRT000403 CDC25A cell division cycle 25A 1 1
MIRT000405 BCL2 BCL2, apoptosis regulator 1 1
MIRT000406 KRAS KRAS proto-oncogene, GTPase 1 1
MIRT002005 HMGA2 high mobility group AT-hook 2 6 8
MIRT003901 APP amyloid beta precursor protein 2 1
MIRT004347 DICER1 dicer 1, ribonuclease III 3 1
MIRT004505 SLC11A2 solute carrier family 11 member 2 6 5
MIRT005549 PDGFA platelet derived growth factor subunit A 3 1
MIRT006398 IL13 interleukin 13 2 1
MIRT006406 MPL MPL proto-oncogene, thrombopoietin receptor 1 1
MIRT032101 RABGAP1L RAB GTPase activating protein 1 like 1 1
MIRT032102 DRD3 dopamine receptor D3 1 1
MIRT032103 SMOX spermine oxidase 1 1
MIRT032104 DAD1 defender against cell death 1 1 1
MIRT032105 EIF4G2 eukaryotic translation initiation factor 4 gamma 2 3 5
MIRT032106 CALCOCO2 calcium binding and coiled-coil domain 2 1 1
MIRT032107 GPR63 G protein-coupled receptor 63 1 1
MIRT032108 FAM135A family with sequence similarity 135 member A 1 1
MIRT032109 CPNE1 copine 1 1 1
MIRT032110 NR4A1 nuclear receptor subfamily 4 group A member 1 1 1
MIRT032111 BUB3 BUB3, mitotic checkpoint protein 1 1
MIRT032112 TBC1D9B TBC1 domain family member 9B 1 1
MIRT032113 LARP4B La ribonucleoprotein domain family member 4B 1 1
MIRT032114 NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 2 3
MIRT032115 FBXO3 F-box protein 3 1 1
MIRT032116 ZNF763 zinc finger protein 763 1 1
MIRT032117 PCNP PEST proteolytic signal containing nuclear protein 1 1
MIRT032118 HOMER1 homer scaffolding protein 1 1 1
MIRT032119 RBM12 RNA binding motif protein 12 1 1
MIRT032120 KMT2A lysine methyltransferase 2A 1 1
MIRT032121 CBR4 carbonyl reductase 4 1 1
MIRT032122 THBS1 thrombospondin 1 2 4
MIRT032123 TLE4 transducin like enhancer of split 4 1 1
MIRT032124 TOMM20 translocase of outer mitochondrial membrane 20 1 1
MIRT032125 TMED4 transmembrane p24 trafficking protein 4 1 1
MIRT032126 AKAP8 A-kinase anchoring protein 8 2 4
MIRT032127 TST thiosulfate sulfurtransferase 1 1
MIRT032128 GPR137B G protein-coupled receptor 137B 1 1
MIRT032129 RALGAPB Ral GTPase activating protein non-catalytic beta subunit 1 1
MIRT032130 IGF2BP3 insulin like growth factor 2 mRNA binding protein 3 2 4
MIRT032131 RPUSD2 RNA pseudouridylate synthase domain containing 2 1 1
MIRT032132 ZBTB24 zinc finger and BTB domain containing 24 1 1
MIRT032133 SPATA2 spermatogenesis associated 2 1 1
MIRT032134 GOLT1B golgi transport 1B 1 1
MIRT032135 ERC1 ELKS/RAB6-interacting/CAST family member 1 1 1
MIRT032136 SREK1IP1 SREK1 interacting protein 1 1 1
MIRT032137 RFX5 regulatory factor X5 1 1
MIRT032138 BIN3 bridging integrator 3 1 1
MIRT032139 CEP120 centrosomal protein 120 2 3
MIRT032140 ZNF526 zinc finger protein 526 1 1
MIRT032141 ISL1 ISL LIM homeobox 1 1 1
MIRT032142 POLR2D RNA polymerase II subunit D 2 5
MIRT032143 SMCR7L mitochondrial elongation factor 1 1 4
MIRT032144 TMEM194A nuclear envelope integral membrane protein 1 1 1
MIRT032145 KATNAL1 katanin catalytic subunit A1 like 1 1 1
MIRT032146 C12orf4 chromosome 12 open reading frame 4 2 3
MIRT032147 TMEM2 transmembrane protein 2 1 1
MIRT032148 DLC1 DLC1 Rho GTPase activating protein 1 1
MIRT032149 TMTC3 transmembrane and tetratricopeptide repeat containing 3 2 3
MIRT032150 SREK1 splicing regulatory glutamic acid and lysine rich protein 1 1 1
MIRT032151 ZNF354B zinc finger protein 354B 1 1
MIRT032152 ZNF200 zinc finger protein 200 2 4
MIRT032153 ADCY9 adenylate cyclase 9 1 1
MIRT032154 TNRC6A trinucleotide repeat containing 6A 1 1
MIRT032155 STK40 serine/threonine kinase 40 1 1
MIRT032156 PCGF3 polycomb group ring finger 3 2 6
MIRT032157 ZBTB39 zinc finger and BTB domain containing 39 1 1
MIRT032158 LIN52 lin-52 DREAM MuvB core complex component 1 1
MIRT032159 RAD9A RAD9 checkpoint clamp component A 1 1
MIRT032160 ARRDC4 arrestin domain containing 4 1 1
MIRT032161 SLC30A6 solute carrier family 30 member 6 1 1
MIRT032162 LBR lamin B receptor 1 1
MIRT032163 C9orf41 carnosine N-methyltransferase 1 1 1
MIRT032164 ESPL1 extra spindle pole bodies like 1, separase 2 5
MIRT032165 ABT1 activator of basal transcription 1 2 9
MIRT032166 NHLRC3 NHL repeat containing 3 2 6
MIRT032167 GLMN glomulin, FKBP associated protein 1 1
MIRT032168 IGDCC4 immunoglobulin superfamily DCC subclass member 4 2 6
MIRT032169 ZNF644 zinc finger protein 644 2 3
MIRT032170 C11orf57 chromosome 11 open reading frame 57 2 5
MIRT032171 FAM104A family with sequence similarity 104 member A 2 2
MIRT032172 SPRYD4 SPRY domain containing 4 1 1
MIRT032173 ARID3A AT-rich interaction domain 3A 2 3
MIRT032174 SLC10A7 solute carrier family 10 member 7 2 6
MIRT032175 ONECUT2 one cut homeobox 2 2 3
MIRT032176 USP24 ubiquitin specific peptidase 24 1 1
MIRT032177 SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 2 4
MIRT032178 TGFBR1 transforming growth factor beta receptor 1 1 1
MIRT032179 HAND1 heart and neural crest derivatives expressed 1 2 3
MIRT032180 KPNA5 karyopherin subunit alpha 5 2 8
MIRT032181 IGF1R insulin like growth factor 1 receptor 2 9
MIRT032182 TMEM135 transmembrane protein 135 1 1
MIRT032183 SLC20A1 solute carrier family 20 member 1 2 4
MIRT032184 ZNF280B zinc finger protein 280B 1 1
MIRT032185 LIN28B lin-28 homolog B 1 1
MIRT032186 IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 2 3
MIRT051710 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 1 1
MIRT051711 PRR13 proline rich 13 1 1
MIRT051712 ZNF746 zinc finger protein 746 1 1
MIRT051713 SLC35A4 solute carrier family 35 member A4 1 1
MIRT051714 RPL31 ribosomal protein L31 1 1
MIRT051715 TPD52L2 tumor protein D52 like 2 1 1
MIRT051716 MRPL51 mitochondrial ribosomal protein L51 1 1
MIRT051717 CTDP1 CTD phosphatase subunit 1 1 1
MIRT051718 RPS6 ribosomal protein S6 1 1
MIRT051719 SENP5 SUMO1/sentrin specific peptidase 5 1 1
MIRT051720 PAXBP1 PAX3 and PAX7 binding protein 1 1 1
MIRT051721 DHX57 DExH-box helicase 57 1 1
MIRT051722 H2AFX H2A histone family member X 1 1
MIRT051723 DSC3 desmocollin 3 1 1
MIRT051724 CIZ1 CDKN1A interacting zinc finger protein 1 1 1
MIRT051725 NCOA1 nuclear receptor coactivator 1 1 1
MIRT051726 LRRC42 leucine rich repeat containing 42 1 1
MIRT051727 UTP6 UTP6, small subunit processome component 1 1
MIRT063194 ADIPOR2 adiponectin receptor 2 2 2
MIRT068153 TXLNA taxilin alpha 2 2
MIRT068788 FNDC3A fibronectin type III domain containing 3A 2 2
MIRT073005 ARID3B AT-rich interaction domain 3B 2 6
MIRT076222 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 6
MIRT083299 ZCCHC3 zinc finger CCHC-type containing 3 2 2
MIRT084975 BACH1 BTB domain and CNC homolog 1 4 3
MIRT095765 GRPEL2 GrpE like 2, mitochondrial 2 10
MIRT112241 MDM4 MDM4, p53 regulator 2 4
MIRT118585 STK4 serine/threonine kinase 4 2 2
MIRT120920 PDE12 phosphodiesterase 12 2 8
MIRT123316 CALU calumenin 2 2
MIRT123975 POLR3D RNA polymerase III subunit D 2 2
MIRT152271 TNFSF9 TNF superfamily member 9 2 2
MIRT153846 NCOA3 nuclear receptor coactivator 3 2 2
MIRT168582 HMGA1 high mobility group AT-hook 1 2 4
MIRT180602 CRY2 cryptochrome circadian clock 2 2 2
MIRT187716 SUOX sulfite oxidase 2 2
MIRT191403 NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit 2 2
MIRT193100 MAPK6 mitogen-activated protein kinase 6 2 2
MIRT215719 C5ORF51 chromosome 5 open reading frame 51 2 10
MIRT218814 CDKN1A cyclin dependent kinase inhibitor 1A 2 2
MIRT240329 UBXN2B UBX domain protein 2B 2 2
MIRT243472 TRIM71 tripartite motif containing 71 2 2
MIRT244068 EDN1 endothelin 1 2 2
MIRT252329 SALL3 spalt like transcription factor 3 2 2
MIRT255313 CDV3 CDV3 homolog 2 2
MIRT259276 PGRMC1 progesterone receptor membrane component 1 2 2
MIRT259478 TXLNG taxilin gamma 2 2
MIRT260706 CLDN12 claudin 12 2 6
MIRT266211 PEX11B peroxisomal biogenesis factor 11 beta 2 2
MIRT266625 CHTOP chromatin target of PRMT1 2 2
MIRT268838 C1ORF21 chromosome 1 open reading frame 21 2 2
MIRT284527 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT294445 ZNF264 zinc finger protein 264 2 2
MIRT297012 RRM2 ribonucleotide reductase regulatory subunit M2 2 2
MIRT300036 BZW1 basic leucine zipper and W2 domains 1 2 4
MIRT300892 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT303319 MXD1 MAX dimerization protein 1 2 2
MIRT309845 NAT8L N-acetyltransferase 8 like 2 2
MIRT322427 PPP2R2A protein phosphatase 2 regulatory subunit Balpha 2 2
MIRT324730 ACER2 alkaline ceramidase 2 2 2
MIRT402056 ATP6V1F ATPase H+ transporting V1 subunit F 2 4
MIRT437855 EIF2C1 argonaute 1, RISC catalytic component 3 1
MIRT438633 TNFRSF10B TNF receptor superfamily member 10b 2 1
MIRT439136 ZEB2 zinc finger E-box binding homeobox 2 0 1
MIRT439137 MYC MYC proto-oncogene, bHLH transcription factor 0 1
MIRT442021 NDUFA4P1 NDUFA4, mitochondrial complex associated pseudogene 1 2 2
MIRT445659 ATP6V1G1 ATPase H+ transporting V1 subunit G1 2 6
MIRT447137 KIF27 kinesin family member 27 2 2
MIRT448263 ZNF774 zinc finger protein 774 2 2
MIRT449006 ANKRD46 ankyrin repeat domain 46 2 2
MIRT449954 FMNL3 formin like 3 2 2
MIRT451156 C19orf53 chromosome 19 open reading frame 53 2 2
MIRT451625 MEIS3P1 Meis homeobox 3 pseudogene 1 2 2
MIRT451694 C1RL complement C1r subcomponent like 2 2
MIRT452093 NUCB2 nucleobindin 2 2 2
MIRT452432 QDPR quinoid dihydropteridine reductase 2 2
MIRT452944 DISC1 disrupted in schizophrenia 1 2 2
MIRT453402 RHD Rh blood group D antigen 2 6
MIRT454165 HIST1H2BK histone cluster 1 H2B family member k 2 2
MIRT454281 FXN frataxin 2 2
MIRT454540 RABL2A RAB, member of RAS oncogene family like 2A 2 2
MIRT454855 ACOT9 acyl-CoA thioesterase 9 2 4
MIRT455677 GLO1 glyoxalase I 2 2
MIRT457249 RABL2B RAB, member of RAS oncogene family like 2B 2 2
MIRT457678 ZNF587 zinc finger protein 587 2 2
MIRT457888 THEM6 thioesterase superfamily member 6 2 4
MIRT458017 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT458280 FUT10 fucosyltransferase 10 2 2
MIRT459737 RRM1 ribonucleotide reductase catalytic subunit M1 2 2
MIRT460454 NOM1 nucleolar protein with MIF4G domain 1 2 4
MIRT460501 FAM105A family with sequence similarity 105 member A 2 6
MIRT460939 NOA1 nitric oxide associated 1 2 4
MIRT461093 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT461365 COL8A1 collagen type VIII alpha 1 chain 2 2
MIRT462383 YAE1D1 Yae1 domain containing 1 2 2
MIRT462781 ZNF8 zinc finger protein 8 2 2
MIRT463418 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT463663 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT464266 VCL vinculin 2 2
MIRT465125 TSC22D2 TSC22 domain family member 2 2 4
MIRT466186 TMED5 transmembrane p24 trafficking protein 5 2 4
MIRT466720 SYNJ2BP synaptojanin 2 binding protein 2 2
MIRT469103 RNF144B ring finger protein 144B 2 2
MIRT469713 RAB40C RAB40C, member RAS oncogene family 2 2
MIRT470424 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 2
MIRT470860 PLXND1 plexin D1 2 2
MIRT471270 PGM2L1 phosphoglucomutase 2 like 1 2 2
MIRT471965 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT472738 MTUS1 microtubule associated scaffold protein 1 2 6
MIRT473135 MLLT10 MLLT10, histone lysine methyltransferase DOT1L cofactor 2 2
MIRT473829 MAP2K7 mitogen-activated protein kinase kinase 7 2 2
MIRT473941 LYN LYN proto-oncogene, Src family tyrosine kinase 2 2
MIRT474024 LRRC20 leucine rich repeat containing 20 2 2
MIRT474501 KLHDC8B kelch domain containing 8B 2 2
MIRT474760 KIAA0930 KIAA0930 2 2
MIRT474908 KCTD21 potassium channel tetramerization domain containing 21 2 2
MIRT475332 IFNLR1 interferon lambda receptor 1 2 2
MIRT475380 ICOSLG inducible T-cell costimulator ligand 2 2
MIRT475734 HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 2 4
MIRT476549 GABPB1 GA binding protein transcription factor beta subunit 1 2 4
MIRT476974 FAM83G family with sequence similarity 83 member G 2 4
MIRT477679 EFHD2 EF-hand domain family member D2 2 2
MIRT479750 CCND1 cyclin D1 2 2
MIRT481194 ATXN7L3B ataxin 7 like 3B 2 4
MIRT481239 ATXN7L3 ataxin 7 like 3 2 2
MIRT481364 ATG9A autophagy related 9A 2 2
MIRT481389 ATG12 autophagy related 12 2 2
MIRT481653 AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 2 2
MIRT481853 AP1S1 adaptor related protein complex 1 sigma 1 subunit 2 2
MIRT482185 AHR aryl hydrocarbon receptor 2 2
MIRT482221 AHCYL2 adenosylhomocysteinase like 2 2 2
MIRT485297 PLAGL2 PLAG1 like zinc finger 2 2 2
MIRT486660 ZNF28 zinc finger protein 28 2 2
MIRT489414 TUBB2A tubulin beta 2A class IIa 2 2
MIRT491865 ZBTB5 zinc finger and BTB domain containing 5 2 8
MIRT492211 SOCS1 suppressor of cytokine signaling 1 2 2
MIRT492625 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2 2
MIRT493322 LIMD2 LIM domain containing 2 2 2
MIRT493902 FAM43A family with sequence similarity 43 member A 2 4
MIRT495969 TBC1D19 TBC1 domain family member 19 2 2
MIRT496113 SNX17 sorting nexin 17 2 2
MIRT497876 SLC12A7 solute carrier family 12 member 7 2 2
MIRT498118 PLEKHO1 pleckstrin homology domain containing O1 2 4
MIRT499406 PLCG2 phospholipase C gamma 2 2 4
MIRT499494 GGA3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 2 2
MIRT499654 SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 2 2
MIRT499943 MFSD8 major facilitator superfamily domain containing 8 2 2
MIRT499998 HIST1H2BD histone cluster 1 H2B family member d 2 4
MIRT500899 STRN striatin 2 4
MIRT501113 SLC5A6 solute carrier family 5 member 6 2 4
MIRT501209 SUMO1 small ubiquitin-like modifier 1 2 2
MIRT501247 SEMA4C semaphorin 4C 2 6
MIRT501327 RNFT1 ring finger protein, transmembrane 1 2 2
MIRT501349 RNF44 ring finger protein 44 2 4
MIRT501388 RBFOX2 RNA binding protein, fox-1 homolog 2 2 10
MIRT501442 RAB11FIP4 RAB11 family interacting protein 4 2 2
MIRT501752 NSD1 nuclear receptor binding SET domain protein 1 2 2
MIRT501941 MBD2 methyl-CpG binding domain protein 2 2 8
MIRT502121 KMT2D lysine methyltransferase 2D 2 4
MIRT502783 CEP135 centrosomal protein 135 2 2
MIRT502840 CELF1 CUGBP Elav-like family member 1 2 2
MIRT505579 SMC1A structural maintenance of chromosomes 1A 2 6
MIRT506360 NUP155 nucleoporin 155 2 6
MIRT507243 FIGN fidgetin, microtubule severing factor 2 8
MIRT507689 COIL coilin 2 6
MIRT508402 C1orf210 chromosome 1 open reading frame 210 2 6
MIRT508666 DIABLO diablo IAP-binding mitochondrial protein 2 4
MIRT508933 AK4 adenylate kinase 4 2 4
MIRT510392 ZNF566 zinc finger protein 566 2 6
MIRT510514 YOD1 YOD1 deubiquitinase 2 6
MIRT511387 IKZF3 IKAROS family zinc finger 3 2 4
MIRT512747 CD59 CD59 molecule (CD59 blood group) 2 4
MIRT515955 C9orf156 tRNA methyltransferase O 2 2
MIRT516084 ZBTB8OS zinc finger and BTB domain containing 8 opposite strand 2 4
MIRT521390 RDX radixin 2 4
MIRT522349 NCKIPSD NCK interacting protein with SH3 domain 2 4
MIRT523627 FZD9 frizzled class receptor 9 2 4
MIRT523734 FBXW2 F-box and WD repeat domain containing 2 2 4
MIRT523983 DVL3 dishevelled segment polarity protein 3 2 2
MIRT524115 DNA2 DNA replication helicase/nuclease 2 2 2
MIRT525728 SOD2 superoxide dismutase 2 2 2
MIRT527764 RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator 2 2
MIRT529728 OPRL1 opioid related nociceptin receptor 1 2 2
MIRT533189 WASL Wiskott-Aldrich syndrome like 2 6
MIRT536379 LEFTY1 left-right determination factor 1 2 2
MIRT543786 RBM12B RNA binding motif protein 12B 2 4
MIRT543869 SLC16A9 solute carrier family 16 member 9 2 2
MIRT545388 PM20D2 peptidase M20 domain containing 2 2 2
MIRT546329 TGFBR3 transforming growth factor beta receptor 3 2 2
MIRT547372 MSI2 musashi RNA binding protein 2 2 2
MIRT547573 LRIG3 leucine rich repeats and immunoglobulin like domains 3 2 4
MIRT548266 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT548346 EPHA4 EPH receptor A4 2 2
MIRT548535 DUSP1 dual specificity phosphatase 1 2 2
MIRT548564 DNAL1 dynein axonemal light chain 1 2 2
MIRT548780 COLEC12 collectin subfamily member 12 2 2
MIRT548972 CCNT2 cyclin T2 2 2
MIRT549022 CBX5 chromobox 5 2 2
MIRT549207 BEND4 BEN domain containing 4 2 4
MIRT549764 ZNF611 zinc finger protein 611 2 6
MIRT549800 KIAA0391 KIAA0391 2 2
MIRT549848 ECHDC1 ethylmalonyl-CoA decarboxylase 1 2 2
MIRT550727 PMPCA peptidase, mitochondrial processing alpha subunit 2 4
MIRT550899 ACTA1 actin, alpha 1, skeletal muscle 2 2
MIRT551284 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 6
MIRT551319 GSG2 histone H3 associated protein kinase 2 6
MIRT552004 RAD18 RAD18, E3 ubiquitin protein ligase 2 2
MIRT552411 ZNF460 zinc finger protein 460 2 4
MIRT553018 USP38 ubiquitin specific peptidase 38 2 2
MIRT555551 PLEKHA3 pleckstrin homology domain containing A3 2 2
MIRT555717 PDZD8 PDZ domain containing 8 2 2
MIRT557967 FAM222B family with sequence similarity 222 member B 2 2
MIRT559088 C19orf47 chromosome 19 open reading frame 47 2 4
MIRT559498 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2 2
MIRT561776 PEG10 paternally expressed 10 2 2
MIRT564403 EMILIN2 elastin microfibril interfacer 2 2 4
MIRT565450 SURF4 surfeit 4 2 2
MIRT566519 PARP16 poly(ADP-ribose) polymerase family member 16 2 2
MIRT567430 GNG5 G protein subunit gamma 5 2 2
MIRT567718 E2F6 E2F transcription factor 6 2 2
MIRT568649 ABHD17C abhydrolase domain containing 17C 2 2
MIRT569499 THYN1 thymocyte nuclear protein 1 2 2
MIRT573821 TGOLN2 trans-golgi network protein 2 2 2
MIRT574364 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT574749 GOLGA4 golgin A4 2 2
MIRT576088 Poteg POTE ankyrin domain family, member G 2 2
MIRT576807 Thbs1 thrombospondin 1 2 3
MIRT616371 RWDD1 RWD domain containing 1 2 2
MIRT617852 FMO4 flavin containing monooxygenase 4 2 2
MIRT642395 ZNF556 zinc finger protein 556 2 2
MIRT680520 PRIM2 DNA primase subunit 2 2 2
MIRT680548 ZNF584 zinc finger protein 584 2 2
MIRT680801 ZNF578 zinc finger protein 578 2 2
MIRT680839 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT681142 INTS7 integrator complex subunit 7 2 2
MIRT681272 RFC2 replication factor C subunit 2 2 2
MIRT681324 ZFAND4 zinc finger AN1-type containing 4 2 4
MIRT681360 BRI3BP BRI3 binding protein 2 2
MIRT681507 STAT2 signal transducer and activator of transcription 2 2 2
MIRT681537 ZNF738 zinc finger protein 738 2 2
MIRT681659 DTX3L deltex E3 ubiquitin ligase 3L 2 2
MIRT681739 RAB19 RAB19, member RAS oncogene family 2 4
MIRT681761 CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 2 2
MIRT681798 EIF4A3 eukaryotic translation initiation factor 4A3 2 2
MIRT681870 DNAH9 dynein axonemal heavy chain 9 2 2
MIRT681942 SLC19A3 solute carrier family 19 member 3 2 2
MIRT682103 ITGA3 integrin subunit alpha 3 2 4
MIRT682182 SLC38A7 solute carrier family 38 member 7 2 2
MIRT682239 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT682385 PHACTR4 phosphatase and actin regulator 4 2 2
MIRT682445 MTX3 metaxin 3 2 2
MIRT682605 CPA4 carboxypeptidase A4 2 2
MIRT682641 COX6B1 cytochrome c oxidase subunit 6B1 2 2
MIRT689328 FPR1 formyl peptide receptor 1 2 2
MIRT689731 ATXN2 ataxin 2 2 2
MIRT691037 ZNF799 zinc finger protein 799 2 2
MIRT691936 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 2
MIRT694885 ZNF417 zinc finger protein 417 2 2
MIRT695256 ZNF443 zinc finger protein 443 2 2
MIRT695414 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2 2
MIRT700588 PRSS22 protease, serine 22 2 2
MIRT701425 NHLRC2 NHL repeat containing 2 2 2
MIRT702485 KIAA1328 KIAA1328 2 2
MIRT702714 IPO9 importin 9 2 2
MIRT704030 EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 2 2
MIRT704422 CTPS1 CTP synthase 1 2 2
MIRT705751 AMD1 adenosylmethionine decarboxylase 1 2 2
MIRT712372 NAP1L1 nucleosome assembly protein 1 like 1 2 2
MIRT713521 PAFAH2 platelet activating factor acetylhydrolase 2 2 2
MIRT734116 Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 3 0
MIRT734252 OPRM1 opioid receptor mu 1 3 0
MIRT735524 CD274 CD274 molecule 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
let-7d Benzene NULL 241 MiRNA PCR array white blood cell 24780745 2014 up-regulated
let-7d Benzene NULL 241 MiRNA PCR array blood mononuclear cells 24780745 2014 up-regulated
let-7d Hydroxamic acid HDACi LAQ824 NULL NULL Microarray breast cancer cell line SKBr3 16452179 2006 down-regulated
let-7d Gemcitabine approved 60750 Northern blot Mz-ChA-1 human cholangiocarcinoma cell lines 16762633 2006 up-regulated
let-7d All-trans-retinoic acid (ATRA) approved 444795 Microarray acute promyelocytic leukemia 17260024 2008 up-regulated
let-7d 17beta-estradiol (E2) approved 5757 Microarray MCF-7 breast cancer cells 19528081 2009 up-regulated
let-7d Cocaine NULL 446220 Quantitative real-time PCR HEK293 cells or rat brain parts 19703567 2009 down-regulated
let-7d Formaldehyde NULL 712 Microarray Human lung epithelial cells (A549) 21147603 2011 down-regulated
let-7d Ginsenoside Rh2 NULL 119307 Microarray human glioma cells U251 21372826 2011 up-regulated
let-7d 5-Fluorouracil approved 3385 Microarray MCF-7 breast cancer cells 21506117 2011 up-regulated
let-7d Arsenic trioxide approved 14888 Quantitative real-time PCR acute promyelocytic leukemia 22072212 2012 up-regulated
let-7d CDF(analogues of curcumin) NULL NULL Quantitative real-time PCR pancreatic cancer cells 22108826 2012 up-regulated
let-7d Marine fungal metabolite 1386A NULL NULL Microarray MCF-7 breast cancer cells. 22159329 2012 down-regulated
let-7d 1,2,6-Tri-O-galloyl-beta-D-glucopyranose NULL NULL Microarray HepG2 hepatocarcinoma cells. 22506400 2011 down-regulated
let-7d Vitamin D3 approved 5280795 Quantitative real-time PCR Plasma 22594500 2012 up-regulated
let-7d Olea europaea leaf extract NULL NULL Quantitative real-time PCR glioblastoma cells. 22722712 2012 up-regulated
let-7d Temozolomide approved 5394 Quantitative real-time PCR glioblastoma cells. 22722712 2012 up-regulated
let-7d Ginsenoside Rh2 NULL 119307 Microarray NSCLC cell line A549 23152132 2013 up-regulated
let-7d Sevoflurane approved 5206 Quantitative real-time PCR lung cell 23124245 2012 down-regulated
let-7d Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse liver 19270793 2009 down-regulated
let-7d Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 down-regulated
let-7d Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-let-7d Doxorubicin 31703 NSC123127 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-let-7d Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (MIA-PaCa-2, PANC-1, Aspc-1, L3.6pl, Colo357, BXPC-3, HPAC)
hsa-let-7d Cisplatin 5460033 NSC119875 approved resistant High Tongue Squamous Cell Carcinoma cell line (Tca8113)
hsa-let-7d Imatinib 5291 NSC743414 approved resistant High Myelogenous Leukemia cell line (MYL)
hsa-let-7d Cisplatin 5460033 NSC119875 approved sensitive Low Oral Cancer Oral Cancer Tumor Initiating Cells
hsa-let-7d Paclitaxel 36314 NSC125973 approved sensitive Low Oral Cancer Oral Cancer Tumor Initiating Cells
hsa-let-7d Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (SKOV3)
hsa-let-7d Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer cell line (HCT-116)
hsa-let-7d Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (C13*, A2780, OV2008)
hsa-let-7d Fluorouracil 3385 NSC19893 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-let-7d Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-let-7d Imatinib 5291 NSC743414 approved resistant High Gastrointestinal Stromal Tumor tissue
hsa-let-7d Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780)
hsa-let-7d Cisplatin 5460033 NSC119875 approved sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-let-7d Mitoxantrone 4212 NSC279836 approved resistant High Breast Cancer cell line (MCF-7)
hsa-let-7d Gefitinib 123631 NSC715055 approved sensitive High Non-Small Cell Lung Cancer cell line (HCC827)
hsa-let-7d 7-Difluoromethoxyl-5,4’-Di-N-Octylgenistein sensitive Low Ovarian Cancer cell line (SKOV3, OVCAR)
hsa-let-7d Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-let-7d Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7)
hsa-let-7d Gefitinib 123631 NSC715055 approved sensitive Low Non-Small Cell Lung Cancer cell line (PC-9)
hsa-let-7d Dabrafenib 44462760 NSC764134 approved sensitive High Melanoma cell line (A375)
hsa-let-7d Osimertinib 71496458 NSC779217 approved sensitive Low Non-Small Cell Lung Cancer cell line (H1975)
hsa-let-7d Doxorubicin 31703 NSC123127 approved sensitive cell line (W1)
hsa-let-7d Vincristine 5978 approved sensitive cell line (W1)
hsa-let-7d Ribavirin+Pegylated IFNa-2b resistant tissue (chronic hepatitis C)
hsa-let-7d Methotrexate 126941 NSC740 approved sensitive cell line (HT29)
hsa-let-7d Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-let-7d Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-let-7d Paclitaxel 36314 NSC125973 approved resistant cell line (SKOV3)
hsa-let-7d Paclitaxel 36314 NSC125973 approved resistant cell line (PC3PR70)
hsa-let-7d Paclitaxel 36314 NSC125973 approved resistant cell line (PC3PR200)
hsa-let-7d Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-let-7d Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-let-7d Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-let-7d-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780)
hsa-let-7d-5p Tamoxifen 2733525 NSC180973 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-let-7d-5p Platinum 23939 resistant Low Ovarian Cancer tissue
hsa-let-7d-5p Imatinib 5291 NSC743414 approved resistant High Gastrointestinal Stromal Tumor cell line (882R-NC, 882R-OE, 882R-KD)
hsa-let-7d-5p Cisplatin 5460033 NSC119875 approved sensitive Low Cervical Cancer tissue
hsa-let-7d-5p Paclitaxel 36314 NSC125973 approved sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-let-7d-5p Trametinib 11707110 NSC758246 approved resistant High Melanoma cell line (WM266) (1uM)
hsa-let-7d-5p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (WM266) (1uM)
hsa-let-7d-5p Trametinib 11707110 NSC758246 approved resistant High Melanoma cell line (WM266) (2uM)
hsa-let-7d-5p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (WM266) (2uM)
hsa-let-7d-5p Cisplatin 5460033 NSC119875 approved sensitive Low Ovarian Cancer cell line (SKOV3, A2780, OVCAR-3, CaOV3)
hsa-let-7d-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780)
hsa-let-7d-5p Tivantinib 11494412 NSC758242 sensitive High Breast Cancer cell line (BT-20, BT-474, BT-549, CAMA-1, HCC1143, HCC1395, HCC1569, HCC1806, HCC-1937, HCC1954, HCC202, HCC38, HCC70, Hs578T, MCF-7, MDA-MB-175VII, MDA-MB-231, MDA-MB-361, MDA-MB-415, MDA-MB-436, MDA-MB-468, SKBR3, T47D, UACC812, EVSA-T, MPE-600 , SK-BR-
hsa-let-7d-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780CP20)
hsa-let-7d-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780CIS)
hsa-let-7d-5p Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-let-7d-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-let-7d-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-let-7d-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM11)
hsa-let-7d-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM17)
hsa-let-7d-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-let-7d-5p Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-let-7d-5p Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-let-7d-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-let-7d-5p Fluorouracil 3385 NSC19893 approved sensitive cell line (HCT15)
hsa-let-7d-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM16)
hsa-let-7d-5p Neoadjuvant chemotherapy resistant tissue (breast cancer)
hsa-let-7d-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-let-7d-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (OVSAHO)

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