pre-miRNA Information
pre-miRNA hsa-mir-744   
Genomic Coordinates chr17: 12081899 - 12081996
Synonyms MIRN744, hsa-mir-744, MIR744
Description Homo sapiens miR-744 stem-loop
Comment This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-744-5p
Sequence 11| UGCGGGGCUAGGGCUAACAGCA |32
Evidence Experimental
Experiments Cloned
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN23015028 1 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs557969425 1 dbSNP
rs748252260 4 dbSNP
rs1470408501 7 dbSNP
rs1178657616 10 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Biomarker Information
Biomarker ID Name Type Discovered From Mode Level Source Testing Methods
B6B8SM miR-744-5p Safety Biomarker (SAF) Clinical/Experimental Data Expression Increase Urine Real-time polymerase chain reaction
Gene Information
Gene Symbol DDX24   
Synonyms -
Description DEAD-box helicase 24
Transcript NM_020414   
Expression
Putative miRNA Targets on DDX24
3'UTR of DDX24
(miRNA target sites are highlighted)
>DDX24|NM_020414|3'UTR
   1 CTGGTCAAGTGTGTCAGTGACTGCACATTGGTTTCTGTTCTCTGGCTATTTGCAAAACCTCTCCCACCCTTGTGTTTCAC
  81 TCCACCACCAACCCCAGGTAAAAAAGTCTCCCTCTCTTCCACTCACACCCATAGCGGGAGAGACCTCATGCAGATTTGCA
 161 TTGTTTTGGAGTAAGAATTCAATGCAGCAGCTTAATTTTTCTGTATTGCAGTGTTTATAGGCTTCTTGTGTGTTAAACTT
 241 GATTTCATAAATTAAAAACAATGGTCAGAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' acGACAAUCGGGAUCG--GGGCGu 5'
            |||||  |:||:||  :::|| 
Target 5' ttCTGTT--CTCTGGCTATTTGCa 3'
33 - 54 84.00 -17.50
2
miRNA  3' acgacaaucgggaUCGGGGCGu 5'
                       ||:|:| | 
Target 5' ccccaggtaaaaaAGTCTCCCt 3'
92 - 113 81.00 -7.40
3
miRNA  3' acGACA-AUCG----GGAU---CGGGGcgu 5'
            |||| | ||    ::||   ||::|   
Target 5' ttCTGTATTGCAGTGTTTATAGGCTTCttg 3'
199 - 228 78.00 -6.84
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN20111636 1 COSMIC
COSN30500830 16 COSMIC
COSN30154948 19 COSMIC
COSN26973046 67 COSMIC
COSN30518088 69 COSMIC
COSN31500908 110 COSMIC
COSN31533986 112 COSMIC
COSN31550667 116 COSMIC
COSN30162561 140 COSMIC
COSN31576603 175 COSMIC
COSN31603632 247 COSMIC
COSN27260194 288 COSMIC
COSN17453863 1592 COSMIC
COSN7034188 2016 COSMIC
COSN22119670 2092 COSMIC
COSN19129411 2121 COSMIC
COSN20111634 2421 COSMIC
COSN5393295 2450 COSMIC
COSN1666808 2786 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1280851603 1 dbSNP
rs374380292 1 dbSNP
rs34699499 3 dbSNP
rs112814907 4 dbSNP
rs201835082 4 dbSNP
rs35895367 4 dbSNP
rs138234118 5 dbSNP
rs1243889107 6 dbSNP
rs143444151 6 dbSNP
rs998367973 8 dbSNP
rs763752831 9 dbSNP
rs762545764 11 dbSNP
rs1411880584 13 dbSNP
rs759436751 15 dbSNP
rs1349094384 16 dbSNP
rs775006297 17 dbSNP
rs1449417324 19 dbSNP
rs1361360759 21 dbSNP
rs181727697 23 dbSNP
rs776446156 25 dbSNP
rs1335071833 28 dbSNP
rs376230067 31 dbSNP
rs1467813142 35 dbSNP
rs765742875 45 dbSNP
rs373461903 48 dbSNP
rs554645559 55 dbSNP
rs888429956 61 dbSNP
rs1442163513 67 dbSNP
rs1019347956 73 dbSNP
rs1048463510 79 dbSNP
rs375942250 92 dbSNP
rs1382647276 93 dbSNP
rs930041589 113 dbSNP
rs1344860204 116 dbSNP
rs1158324784 120 dbSNP
rs1383346441 122 dbSNP
rs1008418864 126 dbSNP
rs889435580 127 dbSNP
rs760390697 130 dbSNP
rs1238068334 134 dbSNP
rs750102270 135 dbSNP
rs536133690 136 dbSNP
rs1238323868 145 dbSNP
rs949263395 148 dbSNP
rs916445995 171 dbSNP
rs1219585660 175 dbSNP
rs575233603 182 dbSNP
rs1459717366 183 dbSNP
rs945538270 184 dbSNP
rs80271596 189 dbSNP
rs538443791 190 dbSNP
rs992234561 194 dbSNP
rs1282800584 197 dbSNP
rs1181795735 204 dbSNP
rs938110356 205 dbSNP
rs1479172074 208 dbSNP
rs1177644077 210 dbSNP
rs936632293 216 dbSNP
rs764464309 220 dbSNP
rs190727067 223 dbSNP
rs977794021 224 dbSNP
rs966824126 228 dbSNP
rs146879573 232 dbSNP
rs534076317 251 dbSNP
rs1331946218 254 dbSNP
rs1233636770 261 dbSNP
rs1282448587 263 dbSNP
rs1026898325 266 dbSNP
rs977297181 273 dbSNP
rs4905150 279 dbSNP
rs762619794 281 dbSNP
rs1193579512 283 dbSNP
rs1198598449 286 dbSNP
rs1347057806 287 dbSNP
rs1248985602 288 dbSNP
rs11849101 295 dbSNP
rs762308853 305 dbSNP
rs1275332998 306 dbSNP
rs34711184 306 dbSNP
rs565547188 306 dbSNP
rs1229942617 307 dbSNP
rs1166248762 314 dbSNP
rs1392761041 315 dbSNP
rs1018477494 321 dbSNP
rs1027954379 322 dbSNP
rs996029108 325 dbSNP
rs1019884465 327 dbSNP
rs35812833 328 dbSNP
rs1007949175 330 dbSNP
rs1379098302 332 dbSNP
rs1325522190 336 dbSNP
rs1224551646 343 dbSNP
rs1158652329 344 dbSNP
rs1007144279 352 dbSNP
rs1266751356 353 dbSNP
rs1359070793 354 dbSNP
rs888733459 359 dbSNP
rs889541114 361 dbSNP
rs193279235 370 dbSNP
rs1027949319 371 dbSNP
rs1027365160 376 dbSNP
rs1262630116 386 dbSNP
rs1428190261 394 dbSNP
rs571492981 405 dbSNP
rs753167260 405 dbSNP
rs1425211277 410 dbSNP
rs1162791800 412 dbSNP
rs772611770 419 dbSNP
rs1000483958 427 dbSNP
rs1421247718 443 dbSNP
rs774835066 444 dbSNP
rs1360811689 451 dbSNP
rs897206077 457 dbSNP
rs1046487061 458 dbSNP
rs903562161 462 dbSNP
rs769317968 464 dbSNP
rs1486228788 467 dbSNP
rs1260095458 473 dbSNP
rs1214669648 476 dbSNP
rs1357948790 477 dbSNP
rs1353280555 495 dbSNP
rs1261718341 501 dbSNP
rs1009797145 503 dbSNP
rs1203674298 504 dbSNP
rs896626276 505 dbSNP
rs548202896 508 dbSNP
rs1183098811 515 dbSNP
rs1383251327 518 dbSNP
rs894982782 522 dbSNP
rs1054919499 523 dbSNP
rs1225605077 524 dbSNP
rs529907627 528 dbSNP
rs562456234 530 dbSNP
rs1344447749 531 dbSNP
rs1451374140 536 dbSNP
rs1304152816 547 dbSNP
rs1406401455 549 dbSNP
rs925205974 554 dbSNP
rs763487521 555 dbSNP
rs1226040833 564 dbSNP
rs926700656 571 dbSNP
rs1282403134 583 dbSNP
rs978138053 591 dbSNP
rs1243756325 597 dbSNP
rs775651823 602 dbSNP
rs1314513325 621 dbSNP
rs1461957347 622 dbSNP
rs1203091637 625 dbSNP
rs769821473 625 dbSNP
rs763257331 631 dbSNP
rs1459032418 637 dbSNP
rs375387159 638 dbSNP
rs1318396882 642 dbSNP
rs972622658 642 dbSNP
rs1401993566 643 dbSNP
rs1412229033 644 dbSNP
rs964495780 657 dbSNP
rs1429521986 662 dbSNP
rs1163150167 663 dbSNP
rs1334113390 665 dbSNP
rs1018444814 667 dbSNP
rs1442320696 676 dbSNP
rs1299179636 679 dbSNP
rs1420406866 680 dbSNP
rs1389981714 686 dbSNP
rs985633907 687 dbSNP
rs1324503024 697 dbSNP
rs952899489 703 dbSNP
rs1191962325 711 dbSNP
rs745953566 712 dbSNP
rs1205346374 713 dbSNP
rs1488085142 715 dbSNP
rs1242973192 716 dbSNP
rs1218014432 721 dbSNP
rs912364834 728 dbSNP
rs532337323 734 dbSNP
rs1269414692 742 dbSNP
rs1027253899 750 dbSNP
rs1425335320 753 dbSNP
rs1410003639 759 dbSNP
rs953942972 765 dbSNP
rs994544146 768 dbSNP
rs776755438 769 dbSNP
rs961384929 779 dbSNP
rs1025437794 786 dbSNP
rs140948828 789 dbSNP
rs1216638004 796 dbSNP
rs540313935 803 dbSNP
rs1364376435 806 dbSNP
rs1215215147 807 dbSNP
rs1272423481 809 dbSNP
rs895244152 819 dbSNP
rs747955816 821 dbSNP
rs572880405 822 dbSNP
rs186604743 823 dbSNP
rs1270454275 829 dbSNP
rs896735169 833 dbSNP
rs903740062 836 dbSNP
rs1042294817 842 dbSNP
rs778642549 853 dbSNP
rs1347565600 856 dbSNP
rs879152222 857 dbSNP
rs1185403968 861 dbSNP
rs1416858246 867 dbSNP
rs542661444 867 dbSNP
rs1002778137 871 dbSNP
rs1427247569 871 dbSNP
rs1366766205 872 dbSNP
rs945309826 877 dbSNP
rs922959986 878 dbSNP
rs1462364414 886 dbSNP
rs1269657819 888 dbSNP
rs1359882597 890 dbSNP
rs371987654 892 dbSNP
rs1040095609 902 dbSNP
rs754918357 903 dbSNP
rs943064644 910 dbSNP
rs528079201 927 dbSNP
rs1358671555 950 dbSNP
rs1219949793 953 dbSNP
rs1286139780 963 dbSNP
rs749124625 965 dbSNP
rs1214708547 968 dbSNP
rs559352746 974 dbSNP
rs868692248 975 dbSNP
rs575147608 979 dbSNP
rs1386379126 981 dbSNP
rs151027121 990 dbSNP
rs919232662 998 dbSNP
rs1410691623 1000 dbSNP
rs372484000 1003 dbSNP
rs1477727903 1018 dbSNP
rs1401662443 1026 dbSNP
rs1317815010 1044 dbSNP
rs1343686553 1050 dbSNP
rs567656813 1060 dbSNP
rs1036372867 1068 dbSNP
rs1420454748 1076 dbSNP
rs973009288 1077 dbSNP
rs1381909040 1086 dbSNP
rs765819835 1088 dbSNP
rs939913218 1088 dbSNP
rs1477175412 1090 dbSNP
rs544627377 1091 dbSNP
rs1462412284 1094 dbSNP
rs577362360 1097 dbSNP
rs1214398692 1113 dbSNP
rs143646557 1114 dbSNP
rs1470695096 1116 dbSNP
rs4905149 1117 dbSNP
rs4905148 1120 dbSNP
rs756921067 1123 dbSNP
rs967783187 1125 dbSNP
rs959426729 1127 dbSNP
rs1273475948 1130 dbSNP
rs1450563866 1131 dbSNP
rs1330736518 1133 dbSNP
rs1215907929 1138 dbSNP
rs1033740061 1141 dbSNP
rs751975942 1146 dbSNP
rs1020541692 1147 dbSNP
rs1223808523 1148 dbSNP
rs1325232669 1148 dbSNP
rs764495305 1150 dbSNP
rs775926513 1155 dbSNP
rs960439868 1157 dbSNP
rs1042653407 1162 dbSNP
rs1438949945 1175 dbSNP
rs1274197609 1181 dbSNP
rs1181498565 1182 dbSNP
rs1250150428 1191 dbSNP
rs1373802675 1193 dbSNP
rs1329961212 1195 dbSNP
rs78067232 1196 dbSNP
rs1009477873 1209 dbSNP
rs1464563921 1218 dbSNP
rs1397082811 1221 dbSNP
rs554506968 1226 dbSNP
rs901764573 1236 dbSNP
rs181774765 1241 dbSNP
rs943031802 1242 dbSNP
rs146814506 1250 dbSNP
rs563356118 1253 dbSNP
rs759580015 1270 dbSNP
rs190110361 1280 dbSNP
rs1195790414 1281 dbSNP
rs75316448 1282 dbSNP
rs920099880 1284 dbSNP
rs8022756 1286 dbSNP
rs149247328 1287 dbSNP
rs761220785 1287 dbSNP
rs1491011885 1288 dbSNP
rs994890379 1289 dbSNP
rs77991212 1296 dbSNP
rs201491987 1297 dbSNP
rs74714986 1297 dbSNP
rs897915717 1297 dbSNP
rs1367404592 1298 dbSNP
rs1425005904 1302 dbSNP
rs1302366676 1304 dbSNP
rs544518987 1310 dbSNP
rs961614154 1313 dbSNP
rs1206447024 1314 dbSNP
rs4900210 1315 dbSNP
rs1279226528 1318 dbSNP
rs1234344496 1322 dbSNP
rs1325297550 1324 dbSNP
rs992092048 1335 dbSNP
rs1295998353 1352 dbSNP
rs1362278295 1356 dbSNP
rs1306481276 1359 dbSNP
rs959353919 1361 dbSNP
rs1391263500 1362 dbSNP
rs1487618266 1365 dbSNP
rs144117428 1368 dbSNP
rs1051432401 1370 dbSNP
rs932601725 1371 dbSNP
rs1033666361 1374 dbSNP
rs1374697422 1375 dbSNP
rs1186777794 1381 dbSNP
rs542600060 1383 dbSNP
rs1300257471 1385 dbSNP
rs1446351313 1388 dbSNP
rs139259023 1390 dbSNP
rs1020752293 1391 dbSNP
rs1289023751 1401 dbSNP
rs1383832728 1412 dbSNP
rs1432206099 1415 dbSNP
rs979241004 1416 dbSNP
rs1174537753 1418 dbSNP
rs1247415657 1429 dbSNP
rs1009816729 1433 dbSNP
rs1436844071 1434 dbSNP
rs901734553 1437 dbSNP
rs1018883461 1446 dbSNP
rs1158131422 1447 dbSNP
rs1418430709 1452 dbSNP
rs1007508993 1459 dbSNP
rs11418786 1459 dbSNP
rs397779509 1459 dbSNP
rs1251231358 1461 dbSNP
rs946593046 1462 dbSNP
rs774147405 1470 dbSNP
rs1159594883 1479 dbSNP
rs913647901 1481 dbSNP
rs8022100 1487 dbSNP
rs1406099793 1491 dbSNP
rs960635590 1504 dbSNP
rs1302736155 1510 dbSNP
rs1256582426 1511 dbSNP
rs749106922 1514 dbSNP
rs1377649305 1519 dbSNP
rs930377297 1529 dbSNP
rs969638325 1534 dbSNP
rs897575027 1536 dbSNP
rs1027786402 1544 dbSNP
rs8003046 1546 dbSNP
rs1203151509 1551 dbSNP
rs898028759 1557 dbSNP
rs1481606037 1566 dbSNP
rs1283178111 1569 dbSNP
rs1015410675 1581 dbSNP
rs34540964 1590 dbSNP
rs11321522 1591 dbSNP
rs398099577 1591 dbSNP
rs58495433 1592 dbSNP
rs71406554 1593 dbSNP
rs33961152 1594 dbSNP
rs927494265 1603 dbSNP
rs1009006098 1607 dbSNP
rs1357896852 1610 dbSNP
rs918114574 1617 dbSNP
rs1464041199 1619 dbSNP
rs1355172460 1622 dbSNP
rs3194654 1635 dbSNP
rs1313886886 1656 dbSNP
rs1350193764 1659 dbSNP
rs1408392646 1666 dbSNP
rs1416786640 1672 dbSNP
rs1346415228 1685 dbSNP
rs1358945585 1694 dbSNP
rs938305873 1696 dbSNP
rs367949925 1707 dbSNP
rs17190876 1716 dbSNP
rs1205057076 1728 dbSNP
rs1273829109 1730 dbSNP
rs1481926987 1745 dbSNP
rs1454417754 1750 dbSNP
rs572959246 1759 dbSNP
rs1021474809 1762 dbSNP
rs1455298572 1765 dbSNP
rs899761160 1766 dbSNP
rs1188948671 1779 dbSNP
rs139614641 1780 dbSNP
rs536393305 1787 dbSNP
rs1370521761 1790 dbSNP
rs988275544 1797 dbSNP
rs568900968 1799 dbSNP
rs1366395860 1801 dbSNP
rs781083826 1802 dbSNP
rs1007476304 1810 dbSNP
rs1215269755 1815 dbSNP
rs1296718497 1816 dbSNP
rs1340027662 1817 dbSNP
rs1247857398 1819 dbSNP
rs1292311699 1823 dbSNP
rs1450672803 1824 dbSNP
rs980466493 1826 dbSNP
rs1204008129 1832 dbSNP
rs969083661 1835 dbSNP
rs1185456120 1841 dbSNP
rs1431663362 1849 dbSNP
rs1485930557 1853 dbSNP
rs1390081575 1857 dbSNP
rs1262005312 1858 dbSNP
rs557110626 1858 dbSNP
rs973679190 1868 dbSNP
rs962186701 1872 dbSNP
rs1386187794 1873 dbSNP
rs1405142849 1883 dbSNP
rs1321781776 1885 dbSNP
rs1347201029 1888 dbSNP
rs1015111024 1899 dbSNP
rs1294290736 1900 dbSNP
rs10137258 1905 dbSNP
rs994932117 1907 dbSNP
rs897545241 1912 dbSNP
rs1029367613 1920 dbSNP
rs996127071 1921 dbSNP
rs1036509406 1924 dbSNP
rs1285860067 1926 dbSNP
rs1295177159 1930 dbSNP
rs150517652 1931 dbSNP
rs766140004 1942 dbSNP
rs1387171111 1947 dbSNP
rs546734685 1950 dbSNP
rs1010798657 1952 dbSNP
rs1056591665 1954 dbSNP
rs938230441 1960 dbSNP
rs1238586370 1964 dbSNP
rs1393730720 1966 dbSNP
rs1161877398 1969 dbSNP
rs1165362353 1970 dbSNP
rs892271639 1973 dbSNP
rs528299066 1984 dbSNP
rs4905147 1985 dbSNP
rs1339828174 1987 dbSNP
rs939060693 1995 dbSNP
rs1191973120 1997 dbSNP
rs751313586 1998 dbSNP
rs549088672 1999 dbSNP
rs1227467902 2001 dbSNP
rs1265851114 2011 dbSNP
rs1325014635 2013 dbSNP
rs1203775726 2016 dbSNP
rs1279924798 2026 dbSNP
rs73348176 2041 dbSNP
rs796092324 2042 dbSNP
rs947687413 2050 dbSNP
rs913930041 2051 dbSNP
rs1189022927 2056 dbSNP
rs920281879 2062 dbSNP
rs988611838 2072 dbSNP
rs1274405798 2074 dbSNP
rs966155622 2077 dbSNP
rs1330626706 2078 dbSNP
rs911696446 2079 dbSNP
rs763833140 2086 dbSNP
rs147368021 2091 dbSNP
rs544703061 2092 dbSNP
rs1273799762 2095 dbSNP
rs1344908826 2096 dbSNP
rs1199185867 2098 dbSNP
rs1328430049 2098 dbSNP
rs907999969 2102 dbSNP
rs987658553 2105 dbSNP
rs1027588201 2109 dbSNP
rs1249865102 2114 dbSNP
rs765681243 2125 dbSNP
rs112083293 2126 dbSNP
rs1377202246 2129 dbSNP
rs1477091506 2136 dbSNP
rs1370123434 2137 dbSNP
rs996241475 2139 dbSNP
rs1428839922 2151 dbSNP
rs968670145 2152 dbSNP
rs1367045042 2157 dbSNP
rs565450663 2170 dbSNP
rs1322488790 2179 dbSNP
rs367629354 2180 dbSNP
rs776581598 2182 dbSNP
rs766392220 2193 dbSNP
rs1394001650 2197 dbSNP
rs1228090140 2198 dbSNP
rs143215460 2198 dbSNP
rs1052821597 2209 dbSNP
rs1056516888 2224 dbSNP
rs1003371154 2240 dbSNP
rs118141241 2245 dbSNP
rs1266974404 2246 dbSNP
rs375924225 2249 dbSNP
rs1191186125 2250 dbSNP
rs1195476944 2257 dbSNP
rs578046911 2259 dbSNP
rs1390674822 2263 dbSNP
rs1448857065 2267 dbSNP
rs1166469090 2271 dbSNP
rs184175725 2276 dbSNP
rs75938204 2284 dbSNP
rs1162238535 2287 dbSNP
rs920229860 2292 dbSNP
rs557288799 2293 dbSNP
rs1195996908 2299 dbSNP
rs1366555274 2300 dbSNP
rs749145276 2302 dbSNP
rs775306730 2309 dbSNP
rs1361960093 2310 dbSNP
rs34896097 2320 dbSNP
rs1246007844 2321 dbSNP
rs940882746 2322 dbSNP
rs908115379 2324 dbSNP
rs988159629 2331 dbSNP
rs1248784976 2335 dbSNP
rs538664373 2337 dbSNP
rs1186523045 2339 dbSNP
rs1196810302 2340 dbSNP
rs913888664 2342 dbSNP
rs1052456293 2347 dbSNP
rs577820439 2350 dbSNP
rs968781719 2356 dbSNP
rs769651426 2358 dbSNP
rs1348629223 2368 dbSNP
rs191920628 2371 dbSNP
rs536496122 2376 dbSNP
rs985935055 2376 dbSNP
rs953177975 2379 dbSNP
rs1396940151 2380 dbSNP
rs920463227 2382 dbSNP
rs956269951 2383 dbSNP
rs1114 2387 dbSNP
rs1230399389 2394 dbSNP
rs1269012335 2399 dbSNP
rs1003893319 2401 dbSNP
rs1206929007 2403 dbSNP
rs867935898 2409 dbSNP
rs75598723 2421 dbSNP
rs397798247 2423 dbSNP
rs58727481 2423 dbSNP
rs1391810882 2425 dbSNP
rs1023486528 2426 dbSNP
rs567451036 2431 dbSNP
rs962021749 2432 dbSNP
rs1420672003 2434 dbSNP
rs1182372756 2437 dbSNP
rs1410813858 2439 dbSNP
rs549223974 2440 dbSNP
rs1011967469 2443 dbSNP
rs1014969215 2447 dbSNP
rs1361399082 2451 dbSNP
rs1013877098 2462 dbSNP
rs1467051740 2466 dbSNP
rs1433740613 2471 dbSNP
rs959758648 2473 dbSNP
rs1395102184 2474 dbSNP
rs1412100514 2475 dbSNP
rs1174979184 2477 dbSNP
rs1034075371 2488 dbSNP
rs1469047965 2489 dbSNP
rs1363784509 2496 dbSNP
rs1303584666 2497 dbSNP
rs1182954933 2502 dbSNP
rs188135371 2507 dbSNP
rs1254184490 2510 dbSNP
rs1481472190 2514 dbSNP
rs1205663328 2516 dbSNP
rs1037492936 2517 dbSNP
rs905348652 2518 dbSNP
rs1210373382 2523 dbSNP
rs886129300 2525 dbSNP
rs183865321 2529 dbSNP
rs1045869 2530 dbSNP
rs892723439 2541 dbSNP
rs1431992027 2544 dbSNP
rs1439927013 2545 dbSNP
rs1309062868 2551 dbSNP
rs1052842877 2553 dbSNP
rs1408298739 2554 dbSNP
rs1295520816 2567 dbSNP
rs1368316170 2568 dbSNP
rs1218756532 2571 dbSNP
rs947595552 2572 dbSNP
rs1344274006 2575 dbSNP
rs914651416 2577 dbSNP
rs1273715903 2579 dbSNP
rs866877307 2583 dbSNP
rs1481957073 2589 dbSNP
rs1223225549 2602 dbSNP
rs1348431924 2604 dbSNP
rs1487845176 2606 dbSNP
rs1278932337 2608 dbSNP
rs944705313 2616 dbSNP
rs774589106 2629 dbSNP
rs988885988 2630 dbSNP
rs1389879867 2633 dbSNP
rs11622635 2636 dbSNP
rs1337260125 2637 dbSNP
rs1036117828 2642 dbSNP
rs777614750 2648 dbSNP
rs1291922944 2651 dbSNP
rs1367265915 2656 dbSNP
rs139217936 2667 dbSNP
rs1296801927 2672 dbSNP
rs1339749983 2685 dbSNP
rs45586440 2688 dbSNP
rs149649233 2692 dbSNP
rs1320797698 2693 dbSNP
rs920416279 2694 dbSNP
rs1269545658 2695 dbSNP
rs1464959162 2699 dbSNP
rs1189706867 2707 dbSNP
rs777957331 2716 dbSNP
rs1398498580 2722 dbSNP
rs1447999146 2725 dbSNP
rs1012081717 2727 dbSNP
rs1414788208 2730 dbSNP
rs940563299 2736 dbSNP
rs1405062247 2737 dbSNP
rs1162957060 2747 dbSNP
rs1390857089 2750 dbSNP
rs899030806 2751 dbSNP
rs1319762515 2752 dbSNP
rs1449927400 2753 dbSNP
rs1284625878 2755 dbSNP
rs1407855528 2759 dbSNP
rs1226191555 2766 dbSNP
rs1159608478 2779 dbSNP
rs1289848028 2780 dbSNP
rs193029502 2790 dbSNP
rs1005060236 2797 dbSNP
rs779274051 2799 dbSNP
rs1268016043 2801 dbSNP
rs1445836703 2801 dbSNP
rs992424561 2810 dbSNP
rs886079267 2811 dbSNP
rs1238347681 2812 dbSNP
rs755457424 2814 dbSNP
rs542827803 2815 dbSNP
rs1414507481 2816 dbSNP
rs575652778 2816 dbSNP
rs563633410 2823 dbSNP
rs1158585619 2827 dbSNP
rs1259939653 2836 dbSNP
rs1416168788 2837 dbSNP
rs1334748794 2840 dbSNP
rs1358299900 2846 dbSNP
rs900760814 2852 dbSNP
rs1446462591 2855 dbSNP
rs1039296679 2859 dbSNP
rs1227216654 2870 dbSNP
rs1285073159 2877 dbSNP
rs1346517229 2880 dbSNP
rs979816890 2880 dbSNP
rs1205588623 2888 dbSNP
rs188979656 2892 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Flp-In T-REx 293-hAGO1 cells
Location of target site CDS
Original Description (Extracted from the article) ... Validation of interactions identified by CLASH suppports their reliability. ...

- Helwak A; Kudla G; Dudnakova T; Tollervey D, 2013, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' acgacaauCGGGAUC-GGGGCGu 5'
                  ||||| | |||:|| 
Target 5' ---atcatGCCCTTGACCCTGCa 3'
1 - 20
Article - Helwak A; Kudla G; Dudnakova T; Tollervey D
- Cell, 2013
MicroRNAs (miRNAs) play key roles in gene regulation, but reliable bioinformatic or experimental identification of their targets remains difficult. To provide an unbiased view of human miRNA targets, we developed a technique for ligation and sequencing of miRNA-target RNA duplexes associated with human AGO1. Here, we report data sets of more than 18,000 high-confidence miRNA-mRNA interactions. The binding of most miRNAs includes the 5' seed region, but around 60% of seed interactions are noncanonical, containing bulged or mismatched nucleotides. Moreover, seed interactions are generally accompanied by specific, nonseed base pairing. 18% of miRNA-mRNA interactions involve the miRNA 3' end, with little evidence for 5' contacts, and some of these were functionally validated. Analyses of miRNA:mRNA base pairing showed that miRNA species systematically differ in their target RNA interactions, and strongly overrepresented motifs were found in the interaction sites of several miRNAs. We speculate that these affect the response of RISC to miRNA-target binding.
LinkOut: [PMID: 23622248]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer 0.66 2.2e-4 0.639 3.9e-4 24 Click to see details
GSE32688 Pancreatic cancer 0.392 1.3e-2 0.368 1.9e-2 32 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.686 2.1e-2 0.600 4.4e-2 9 Click to see details
GSE35602 Colorectal cancer stromal tissue 0.368 3.5e-2 0.348 4.4e-2 25 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.4 4.0e-2 0.579 3.7e-3 20 Click to see details
GSE28260 Renal cortex and medulla 0.429 7.2e-2 0.308 1.5e-1 13 Click to see details
GSE21032 Prostate cancer -0.16 7.4e-2 -0.120 1.4e-1 83 Click to see details
GSE26953 Aortic valvular endothelial cells -0.234 1.4e-1 -0.073 3.7e-1 24 Click to see details
GSE19350 CNS germ cell tumors -0.344 1.4e-1 -0.343 1.4e-1 12 Click to see details
GSE19783 ER+ ER+ breast cancer -0.256 1.4e-1 -0.238 1.6e-1 20 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.202 1.7e-1 0.205 1.6e-1 25 Click to see details
GSE21687 Ependynoma primary tumors -0.101 2.1e-1 -0.135 1.4e-1 64 Click to see details
GSE42095 Differentiated embryonic stem cells -0.158 2.4e-1 -0.251 1.2e-1 23 Click to see details
GSE19536 Breast cancer 0.053 3.0e-1 -0.022 4.1e-1 100 Click to see details
GSE19783 ER- ER- breast cancer 0.059 3.0e-1 0.016 4.4e-1 79 Click to see details
GSE38226 Liver fibrosis -0.072 3.8e-1 -0.028 4.5e-1 21 Click to see details
GSE17498 Multiple myeloma 0.049 3.8e-1 0.051 3.8e-1 40 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
KIRP -0.481 0 -0.457 0 32 Click to see details
KICH -0.357 0.04 -0.333 0.05 25 Click to see details
LIHC 0.247 0.04 0.199 0.09 49 Click to see details
BRCA -0.183 0.05 -0.165 0.07 84 Click to see details
KIRC -0.181 0.07 -0.206 0.05 68 Click to see details
HNSC -0.226 0.08 -0.207 0.09 42 Click to see details
UCEC -0.33 0.08 -0.333 0.08 19 Click to see details
LUAD 0.421 0.09 0.217 0.25 12 Click to see details
COAD 0.483 0.11 0.405 0.16 8 Click to see details
STAD -0.155 0.2 -0.151 0.2 32 Click to see details
THCA 0.107 0.21 0.162 0.11 59 Click to see details
PCPG -0.752 0.23 -1.000 0.5 3 Click to see details
CHOL -0.284 0.23 -0.467 0.1 9 Click to see details
ESCA 0.23 0.25 0.182 0.3 11 Click to see details
BLCA -0.151 0.27 0.115 0.32 18 Click to see details
LUSC -0.093 0.29 0.010 0.48 38 Click to see details
PRAD 0.078 0.3 0.061 0.34 50 Click to see details
CESC 0.458 0.35 0.500 0.33 3 Click to see details
PAAD 0.3 0.35 0.400 0.3 4 Click to see details
PAAD 0.3 0.35 0.400 0.3 4 Click to see details
PAAD 0.3 0.35 0.400 0.3 4 Click to see details
412 hsa-miR-744-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT016085 ARL15 ADP ribosylation factor like GTPase 15 1 1
MIRT016086 AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 1 2
MIRT016087 PPTC7 PTC7 protein phosphatase homolog 2 3
MIRT016088 RASSF1 Ras association domain family member 1 1 1
MIRT016089 IER5 immediate early response 5 1 1
MIRT037383 UFC1 ubiquitin-fold modifier conjugating enzyme 1 1 1
MIRT037384 STAM2 signal transducing adaptor molecule 2 1 1
MIRT037385 SRRM2 serine/arginine repetitive matrix 2 1 1
MIRT037386 DCXR dicarbonyl and L-xylulose reductase 1 1
MIRT037387 TSPAN17 tetraspanin 17 1 1
MIRT037388 ACTB actin beta 1 1
MIRT037389 HIST1H2BC histone cluster 1 H2B family member c 1 1
MIRT037390 ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 1 1
MIRT037391 VDAC1 voltage dependent anion channel 1 1 1
MIRT037392 RNASEK ribonuclease K 1 1
MIRT037393 CDK16 cyclin dependent kinase 16 1 1
MIRT037394 ZCCHC24 zinc finger CCHC-type containing 24 1 1
MIRT037395 ARRDC2 arrestin domain containing 2 1 1
MIRT037396 SGMS1 sphingomyelin synthase 1 1 1
MIRT037397 HSPD1 heat shock protein family D (Hsp60) member 1 1 1
MIRT037398 MRPL46 mitochondrial ribosomal protein L46 1 1
MIRT037399 RHEB Ras homolog, mTORC1 binding 1 1
MIRT037400 ND1 NADH dehydrogenase, subunit 1 (complex I) 1 1
MIRT037401 TP53I13 tumor protein p53 inducible protein 13 1 1
MIRT037402 CD44 CD44 molecule (Indian blood group) 1 1
MIRT037403 USP12 ubiquitin specific peptidase 12 1 1
MIRT037404 AP2B1 adaptor related protein complex 2 beta 1 subunit 1 1
MIRT037405 RPL18A ribosomal protein L18a 1 1
MIRT037406 PPP1CA protein phosphatase 1 catalytic subunit alpha 1 1
MIRT037407 TNRC6B trinucleotide repeat containing 6B 1 1
MIRT037408 PXK PX domain containing serine/threonine kinase like 1 1
MIRT037409 TDRKH tudor and KH domain containing 1 1
MIRT037410 PRRC2A proline rich coiled-coil 2A 1 1
MIRT037411 ATP11A ATPase phospholipid transporting 11A 1 1
MIRT037412 NDE1 nudE neurodevelopment protein 1 1 1
MIRT037413 STK16 serine/threonine kinase 16 1 1
MIRT037414 PSMB2 proteasome subunit beta 2 1 1
MIRT037415 EPN1 epsin 1 1 1
MIRT037416 EN2 engrailed homeobox 2 1 1
MIRT037417 LARP1 La ribonucleoprotein domain family member 1 1 1
MIRT037418 SRCAP Snf2 related CREBBP activator protein 1 1
MIRT037419 SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 1 1
MIRT037420 AP2A2 adaptor related protein complex 2 alpha 2 subunit 1 1
MIRT037421 ACTG1 actin gamma 1 1 1
MIRT037422 PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing 1 1
MIRT037423 UBE2O ubiquitin conjugating enzyme E2 O 1 1
MIRT037424 KLHL15 kelch like family member 15 1 1
MIRT037425 SECISBP2 SECIS binding protein 2 1 1
MIRT037426 KIAA0922 transmembrane 131 like 1 1
MIRT037427 PTMA prothymosin, alpha 1 1
MIRT037428 WDR45B WD repeat domain 45B 1 1
MIRT037429 ZNF282 zinc finger protein 282 1 1
MIRT037430 GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 1 1
MIRT037431 TNKS tankyrase 1 1
MIRT037432 NOP2 NOP2 nucleolar protein 1 1
MIRT037433 GAK cyclin G associated kinase 1 1
MIRT037434 ATP6 ATP synthase F0 subunit 6 1 1
MIRT037435 DIDO1 death inducer-obliterator 1 1 1
MIRT037436 RPL3 ribosomal protein L3 1 1
MIRT037437 AIMP2 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 1 1
MIRT037438 PIGC phosphatidylinositol glycan anchor biosynthesis class C 1 1
MIRT037439 ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 1 1
MIRT037440 USP21 ubiquitin specific peptidase 21 1 1
MIRT037441 NUFIP2 NUFIP2, FMR1 interacting protein 2 1 1
MIRT037442 RPS6 ribosomal protein S6 1 1
MIRT037443 ILKAP ILK associated serine/threonine phosphatase 1 1
MIRT037444 COX1 cytochrome c oxidase subunit I 1 1
MIRT037445 VPS37C VPS37C, ESCRT-I subunit 1 1
MIRT037446 CDK12 cyclin dependent kinase 12 1 1
MIRT037447 RBM8A RNA binding motif protein 8A 1 1
MIRT037448 CKB creatine kinase B 1 1
MIRT037449 DHX57 DExH-box helicase 57 1 1
MIRT037450 DDX23 DEAD-box helicase 23 1 1
MIRT037451 ABI3 ABI family member 3 1 1
MIRT037452 GATAD2B GATA zinc finger domain containing 2B 1 1
MIRT037453 PDPK1 3-phosphoinositide dependent protein kinase 1 1 1
MIRT037454 C17orf70 Fanconi anemia core complex associated protein 100 1 1
MIRT037455 SKI SKI proto-oncogene 1 1
MIRT037456 KCTD11 potassium channel tetramerization domain containing 11 1 1
MIRT037457 GNB2L1 receptor for activated C kinase 1 1 1
MIRT037458 NCOA3 nuclear receptor coactivator 3 1 1
MIRT037459 PAK4 p21 (RAC1) activated kinase 4 2 3
MIRT037460 GDI2 GDP dissociation inhibitor 2 1 1
MIRT037461 SLC2A4RG SLC2A4 regulator 1 1
MIRT037462 SLX4 SLX4 structure-specific endonuclease subunit 1 1
MIRT037463 COPA coatomer protein complex subunit alpha 1 1
MIRT037464 GPRASP2 G protein-coupled receptor associated sorting protein 2 1 1
MIRT037465 GGA3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 1 1
MIRT037466 LIMS1 LIM zinc finger domain containing 1 1 1
MIRT037467 COTL1 coactosin like F-actin binding protein 1 1 1
MIRT037468 CAPNS1 calpain small subunit 1 1 1
MIRT037469 FRZB frizzled-related protein 1 1
MIRT037470 UBQLN4 ubiquilin 4 1 1
MIRT037471 NUP153 nucleoporin 153 1 1
MIRT037472 TMEM175 transmembrane protein 175 1 1
MIRT037473 HIST1H2BD histone cluster 1 H2B family member d 1 1
MIRT037474 SREBF1 sterol regulatory element binding transcription factor 1 1 1
MIRT037475 BCL2L12 BCL2 like 12 1 1
MIRT037476 HIST2H2AA3 histone cluster 2 H2A family member a3 1 1
MIRT037477 MINK1 misshapen like kinase 1 1 1
MIRT037478 PDXK pyridoxal kinase 1 1
MIRT037479 FAM110A family with sequence similarity 110 member A 1 1
MIRT037480 ZNF598 zinc finger protein 598 1 1
MIRT037481 ILK integrin linked kinase 1 1
MIRT037482 HINT1 histidine triad nucleotide binding protein 1 1 1
MIRT037483 WBP2 WW domain binding protein 2 1 1
MIRT037484 CYTB cytochrome b 1 1
MIRT037485 SCAMP2 secretory carrier membrane protein 2 1 1
MIRT037486 TRIM33 tripartite motif containing 33 1 1
MIRT037487 SLC25A3 solute carrier family 25 member 3 1 1
MIRT037488 IRS4 insulin receptor substrate 4 1 1
MIRT037489 TSR1 TSR1, ribosome maturation factor 1 1
MIRT037490 TCOF1 treacle ribosome biogenesis factor 1 1 1
MIRT037491 ATXN2L ataxin 2 like 1 1
MIRT037492 MTOR mechanistic target of rapamycin kinase 1 1
MIRT037493 ZNF318 zinc finger protein 318 1 1
MIRT037494 HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 2 3
MIRT037495 SAMD4B sterile alpha motif domain containing 4B 1 1
MIRT037496 STMN1 stathmin 1 1 1
MIRT037497 SAT1 spermidine/spermine N1-acetyltransferase 1 1 1
MIRT037498 SALL1 spalt like transcription factor 1 1 1
MIRT037499 ZSCAN18 zinc finger and SCAN domain containing 18 1 1
MIRT037500 SLC35D1 solute carrier family 35 member D1 1 1
MIRT037501 TM9SF3 transmembrane 9 superfamily member 3 1 1
MIRT037502 TIAM1 T-cell lymphoma invasion and metastasis 1 1 1
MIRT037503 CHD5 chromodomain helicase DNA binding protein 5 1 1
MIRT037504 BAG6 BCL2 associated athanogene 6 1 1
MIRT037505 MED28 mediator complex subunit 28 1 1
MIRT037506 ANKRD52 ankyrin repeat domain 52 1 1
MIRT037507 MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 1 1
MIRT037508 PPDPF pancreatic progenitor cell differentiation and proliferation factor 1 1
MIRT037509 PRKACA protein kinase cAMP-activated catalytic subunit alpha 1 1
MIRT037510 HPCAL4 hippocalcin like 4 1 1
MIRT037511 ZNF256 zinc finger protein 256 1 1
MIRT037512 CGNL1 cingulin like 1 1 1
MIRT037513 TUBA1B tubulin alpha 1b 1 1
MIRT037514 LNPEP leucyl and cystinyl aminopeptidase 1 1
MIRT037515 PDE4A phosphodiesterase 4A 1 1
MIRT037516 HOXD11 homeobox D11 2 3
MIRT037517 QARS glutaminyl-tRNA synthetase 1 1
MIRT037518 G3BP1 G3BP stress granule assembly factor 1 1 1
MIRT037519 PLEKHM2 pleckstrin homology and RUN domain containing M2 1 1
MIRT037520 POLR2A RNA polymerase II subunit A 1 1
MIRT037521 KIAA1462 junctional cadherin 5 associated 1 1
MIRT037522 SF3A1 splicing factor 3a subunit 1 1 1
MIRT037523 YBX1 Y-box binding protein 1 1 1
MIRT037524 PTGES3 prostaglandin E synthase 3 1 1
MIRT037525 FOXO3 forkhead box O3 1 1
MIRT037526 ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) 1 1
MIRT037527 AARS alanyl-tRNA synthetase 1 1
MIRT037528 ZNF155 zinc finger protein 155 1 1
MIRT037529 NCS1 neuronal calcium sensor 1 1 1
MIRT037530 FKBP4 FK506 binding protein 4 1 1
MIRT037531 ARHGDIA Rho GDP dissociation inhibitor alpha 1 1
MIRT037532 MAPK7 mitogen-activated protein kinase 7 1 1
MIRT037533 AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 1 1
MIRT037534 HIST1H1E histone cluster 1 H1 family member e 1 1
MIRT037535 MLF2 myeloid leukemia factor 2 1 1
MIRT037536 EDC3 enhancer of mRNA decapping 3 1 1
MIRT037537 CHRAC1 chromatin accessibility complex 1 1 1
MIRT037538 WIPF3 WAS/WASL interacting protein family member 3 1 1
MIRT037539 COX2 cytochrome c oxidase subunit II 1 1
MIRT037540 SRSF1 serine and arginine rich splicing factor 1 1 1
MIRT037541 CTNNBIP1 catenin beta interacting protein 1 1 1
MIRT037542 RPL4 ribosomal protein L4 1 1
MIRT037543 COX3 cytochrome c oxidase III 1 1
MIRT037544 DDX54 DEAD-box helicase 54 1 1
MIRT037545 TOB2 transducer of ERBB2, 2 1 1
MIRT037546 MAN2C1 mannosidase alpha class 2C member 1 1 1
MIRT037547 SMCR7L mitochondrial elongation factor 1 1 1
MIRT037548 RPLP1 ribosomal protein lateral stalk subunit P1 1 1
MIRT037549 RAN RAN, member RAS oncogene family 1 1
MIRT037550 NONO non-POU domain containing octamer binding 1 1
MIRT037551 CYB5R3 cytochrome b5 reductase 3 1 1
MIRT037552 SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 1 1
MIRT037553 COLGALT1 collagen beta(1-O)galactosyltransferase 1 1 1
MIRT037554 MGRN1 mahogunin ring finger 1 1 1
MIRT037555 ANAPC1 anaphase promoting complex subunit 1 1 1
MIRT037556 TBX1 T-box 1 1 1
MIRT037557 NXPH4 neurexophilin 4 1 1
MIRT037558 HSPA1B heat shock protein family A (Hsp70) member 1B 1 1
MIRT037559 UBE2A ubiquitin conjugating enzyme E2 A 1 1
MIRT037560 KPNB1 karyopherin subunit beta 1 1 1
MIRT037561 NDUFB10 NADH:ubiquinone oxidoreductase subunit B10 1 1
MIRT037562 SYMPK symplekin 1 1
MIRT037563 SYPL1 synaptophysin like 1 1 1
MIRT037564 LRP3 LDL receptor related protein 3 1 1
MIRT037565 DDX24 DEAD-box helicase 24 1 1
MIRT037566 WDR37 WD repeat domain 37 1 1
MIRT037567 RPS14 ribosomal protein S14 1 1
MIRT037568 FAM53C family with sequence similarity 53 member C 1 1
MIRT037569 NMT1 N-myristoyltransferase 1 1 1
MIRT037570 PAGR1 PAXIP1 associated glutamate rich protein 1 1 1
MIRT037571 AKT2 AKT serine/threonine kinase 2 1 1
MIRT037572 TMEM14C transmembrane protein 14C 1 1
MIRT037573 MEX3D mex-3 RNA binding family member D 1 1
MIRT037574 BRAF B-Raf proto-oncogene, serine/threonine kinase 1 1
MIRT037575 POLR2L RNA polymerase II subunit L 1 1
MIRT037576 SERP1 stress associated endoplasmic reticulum protein 1 1 1
MIRT037577 C8orf33 chromosome 8 open reading frame 33 1 1
MIRT037578 NR1D2 nuclear receptor subfamily 1 group D member 2 1 1
MIRT037579 POLD3 DNA polymerase delta 3, accessory subunit 1 1
MIRT037580 HMGA1 high mobility group AT-hook 1 1 1
MIRT037581 SLC35B4 solute carrier family 35 member B4 1 1
MIRT037582 PELP1 proline, glutamate and leucine rich protein 1 1 1
MIRT037583 PLEKHG2 pleckstrin homology and RhoGEF domain containing G2 1 1
MIRT037584 RPL7A ribosomal protein L7a 1 1
MIRT037585 LAIR1 leukocyte associated immunoglobulin like receptor 1 1 1
MIRT037586 RPL10 ribosomal protein L10 1 1
MIRT037587 MRPS16 mitochondrial ribosomal protein S16 1 1
MIRT037588 SRM spermidine synthase 1 1
MIRT037589 EIF3K eukaryotic translation initiation factor 3 subunit K 1 1
MIRT037590 DESI1 desumoylating isopeptidase 1 1 1
MIRT037591 BET1 Bet1 golgi vesicular membrane trafficking protein 1 1
MIRT037592 HTRA2 HtrA serine peptidase 2 1 1
MIRT037593 LARP6 La ribonucleoprotein domain family member 6 1 1
MIRT037594 NOTCH2 notch 2 1 1
MIRT037595 ADCY9 adenylate cyclase 9 1 1
MIRT037596 C6orf62 chromosome 6 open reading frame 62 1 1
MIRT037597 FBXL19 F-box and leucine rich repeat protein 19 1 1
MIRT037598 L3MBTL2 L3MBTL2, polycomb repressive complex 1 subunit 1 1
MIRT037599 TRIM28 tripartite motif containing 28 1 1
MIRT037600 LGALS3 galectin 3 1 1
MIRT037601 IGSF8 immunoglobulin superfamily member 8 1 1
MIRT037602 LIN37 lin-37 DREAM MuvB core complex component 1 1
MIRT037603 PTPRF protein tyrosine phosphatase, receptor type F 1 1
MIRT037604 MTSS1L MTSS1L, I-BAR domain containing 1 1
MIRT037605 TRMT2A tRNA methyltransferase 2 homolog A 1 1
MIRT037606 DVL1 dishevelled segment polarity protein 1 1 1
MIRT037607 ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B) 1 1
MIRT037608 TOR2A torsin family 2 member A 1 1
MIRT037609 RPS6KA5 ribosomal protein S6 kinase A5 1 1
MIRT037610 SMYD4 SET and MYND domain containing 4 1 1
MIRT037611 TJAP1 tight junction associated protein 1 1 1
MIRT037612 IRAK1 interleukin 1 receptor associated kinase 1 1 1
MIRT037613 PPM1M protein phosphatase, Mg2+/Mn2+ dependent 1M 1 1
MIRT037614 EIF4A2 eukaryotic translation initiation factor 4A2 1 1
MIRT037615 GFER growth factor, augmenter of liver regeneration 1 1
MIRT037616 PKP2 plakophilin 2 1 1
MIRT037617 FARSB phenylalanyl-tRNA synthetase beta subunit 1 1
MIRT037618 OPRD1 opioid receptor delta 1 1 1
MIRT037619 CCNY cyclin Y 1 1
MIRT037620 CNOT1 CCR4-NOT transcription complex subunit 1 1 1
MIRT037621 CXCL16 C-X-C motif chemokine ligand 16 1 1
MIRT037622 CEBPA CCAAT/enhancer binding protein alpha 1 1
MIRT037623 DDX11 DEAD/H-box helicase 11 1 1
MIRT037624 URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) 1 1
MIRT037625 SBF1 SET binding factor 1 1 1
MIRT037626 GNB2 G protein subunit beta 2 1 1
MIRT037627 KMT2D lysine methyltransferase 2D 2 3
MIRT037628 DDX17 DEAD-box helicase 17 1 1
MIRT037629 SORBS3 sorbin and SH3 domain containing 3 1 1
MIRT037630 TAPBP TAP binding protein 1 1
MIRT037631 BCR BCR, RhoGEF and GTPase activating protein 1 1
MIRT037632 RPL18 ribosomal protein L18 1 1
MIRT037633 INTS3 integrator complex subunit 3 1 1
MIRT037634 CDC25B cell division cycle 25B 1 1
MIRT037635 LDOC1L retrotransposon Gag like 6 1 1
MIRT037636 TUB tubby bipartite transcription factor 1 1
MIRT037637 NUDT2 nudix hydrolase 2 1 1
MIRT037638 CDAN1 codanin 1 1 1
MIRT037639 MRS2 MRS2, magnesium transporter 1 1
MIRT037640 PYGB glycogen phosphorylase B 1 1
MIRT037641 LDLRAD3 low density lipoprotein receptor class A domain containing 3 1 1
MIRT037642 COL5A1 collagen type V alpha 1 chain 1 1
MIRT037643 ATF7IP activating transcription factor 7 interacting protein 1 1
MIRT037644 AGO1 argonaute 1, RISC catalytic component 1 1
MIRT037645 ZNF212 zinc finger protein 212 1 1
MIRT037646 TSC2 TSC complex subunit 2 1 1
MIRT037647 FASN fatty acid synthase 1 1
MIRT037648 NOL9 nucleolar protein 9 1 1
MIRT037649 CLUH clustered mitochondria homolog 1 1
MIRT037650 PHF8 PHD finger protein 8 1 1
MIRT037651 EIF4G1 eukaryotic translation initiation factor 4 gamma 1 1 1
MIRT037652 TRAPPC12 trafficking protein particle complex 12 1 1
MIRT037653 HOXC11 homeobox C11 1 1
MIRT037654 DGCR14 ess-2 splicing factor homolog 1 1
MIRT037655 SLC25A1 solute carrier family 25 member 1 1 1
MIRT037656 MEX3C mex-3 RNA binding family member C 1 1
MIRT037657 RAI1 retinoic acid induced 1 1 1
MIRT037658 LY6E lymphocyte antigen 6 family member E 1 1
MIRT037659 SEC16A SEC16 homolog A, endoplasmic reticulum export factor 1 1
MIRT037660 RPL37 ribosomal protein L37 1 1
MIRT037661 CNN2 calponin 2 1 1
MIRT037662 ALDH18A1 aldehyde dehydrogenase 18 family member A1 1 1
MIRT037663 POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1 1
MIRT037664 EIF4A1 eukaryotic translation initiation factor 4A1 1 1
MIRT037665 PIM3 Pim-3 proto-oncogene, serine/threonine kinase 1 1
MIRT037666 PTPMT1 protein tyrosine phosphatase, mitochondrial 1 1 1
MIRT037667 NCEH1 neutral cholesterol ester hydrolase 1 1 1
MIRT037668 ART5 ADP-ribosyltransferase 5 1 1
MIRT037669 MRPS2 mitochondrial ribosomal protein S2 1 1
MIRT037670 NCL nucleolin 1 1
MIRT037671 NCKAP5L NCK associated protein 5 like 1 1
MIRT037672 ZCCHC14 zinc finger CCHC-type containing 14 1 1
MIRT037673 CCDC71 coiled-coil domain containing 71 1 1
MIRT037674 SURF4 surfeit 4 1 1
MIRT037675 RPL13 ribosomal protein L13 1 1
MIRT037676 ACTN4 actinin alpha 4 1 1
MIRT037677 PA2G4 proliferation-associated 2G4 1 1
MIRT037678 MIF macrophage migration inhibitory factor 1 1
MIRT037679 UBE2N ubiquitin conjugating enzyme E2 N 1 1
MIRT037680 LYNX1 Ly6/neurotoxin 1 1 1
MIRT037681 TACC3 transforming acidic coiled-coil containing protein 3 1 1
MIRT037682 GSR glutathione-disulfide reductase 1 1
MIRT037683 GSK3A glycogen synthase kinase 3 alpha 1 1
MIRT037684 ZMYM3 zinc finger MYM-type containing 3 1 1
MIRT037685 ERP29 endoplasmic reticulum protein 29 1 1
MIRT037686 MATR3 matrin 3 1 1
MIRT037687 FANCG Fanconi anemia complementation group G 1 1
MIRT037688 FAM83G family with sequence similarity 83 member G 1 1
MIRT037689 DUSP18 dual specificity phosphatase 18 1 1
MIRT037690 MYC MYC proto-oncogene, bHLH transcription factor 3 2
MIRT037691 TSPAN7 tetraspanin 7 1 1
MIRT037692 ATMIN ATM interactor 1 1
MIRT037693 SEPT2 septin 2 1 1
MIRT037694 FOXRED2 FAD dependent oxidoreductase domain containing 2 1 1
MIRT037695 TECR trans-2,3-enoyl-CoA reductase 1 1
MIRT037696 MRPL11 mitochondrial ribosomal protein L11 1 1
MIRT037697 IP6K1 inositol hexakisphosphate kinase 1 1 1
MIRT037698 PSMD4 proteasome 26S subunit, non-ATPase 4 1 1
MIRT037699 SH3GL1 SH3 domain containing GRB2 like 1, endophilin A2 1 1
MIRT037700 CTNNB1 catenin beta 1 1 1
MIRT037701 TMEM189 transmembrane protein 189 1 1
MIRT037702 LDLR low density lipoprotein receptor 1 1
MIRT037703 OGFR opioid growth factor receptor 1 1
MIRT037704 ADAP2 ArfGAP with dual PH domains 2 1 1
MIRT037705 LIPA lipase A, lysosomal acid type 1 1
MIRT037706 SNAPC4 small nuclear RNA activating complex polypeptide 4 1 1
MIRT037707 FBN2 fibrillin 2 1 1
MIRT037708 ZNF704 zinc finger protein 704 1 1
MIRT037709 EIF3M eukaryotic translation initiation factor 3 subunit M 1 1
MIRT037710 SMC1A structural maintenance of chromosomes 1A 1 1
MIRT037711 FZR1 fizzy and cell division cycle 20 related 1 1 1
MIRT037712 NANOS1 nanos C2HC-type zinc finger 1 1 1
MIRT037713 PRR12 proline rich 12 1 1
MIRT037714 PHC2 polyhomeotic homolog 2 1 1
MIRT037715 NOP9 NOP9 nucleolar protein 1 1
MIRT037716 HM13 histocompatibility minor 13 1 1
MIRT037717 PRDX5 peroxiredoxin 5 1 1
MIRT037718 IRGQ immunity related GTPase Q 1 1
MIRT037719 TGFB1 transforming growth factor beta 1 7 2
MIRT037720 MARCH3 membrane associated ring-CH-type finger 3 1 1
MIRT037721 TBX2 T-box 2 1 1
MIRT037722 TSC22D3 TSC22 domain family member 3 1 1
MIRT037723 DUT deoxyuridine triphosphatase 1 1
MIRT037724 FAM171A2 family with sequence similarity 171 member A2 1 1
MIRT037725 FGFR1 fibroblast growth factor receptor 1 1 1
MIRT037726 FRAT1 FRAT1, WNT signaling pathway regulator 1 1
MIRT037727 PSMD11 proteasome 26S subunit, non-ATPase 11 1 1
MIRT037728 PABPC1 poly(A) binding protein cytoplasmic 1 1 1
MIRT037729 ENO1 enolase 1 1 1
MIRT037730 AP3D1 adaptor related protein complex 3 delta 1 subunit 1 1
MIRT037731 TUBA1A tubulin alpha 1a 1 1
MIRT037732 ULK3 unc-51 like kinase 3 1 1
MIRT037733 PIP5K1A phosphatidylinositol-4-phosphate 5-kinase type 1 alpha 1 1
MIRT037734 SLC25A46 solute carrier family 25 member 46 1 1
MIRT037735 MED15 mediator complex subunit 15 1 1
MIRT037736 IRF2BP1 interferon regulatory factor 2 binding protein 1 1 1
MIRT037737 UBA1 ubiquitin like modifier activating enzyme 1 1 1
MIRT037738 ATHL1 protein-glucosylgalactosylhydroxylysine glucosidase 1 1
MIRT037739 CTNNA1 catenin alpha 1 1 1
MIRT037740 ADRM1 adhesion regulating molecule 1 1 1
MIRT037741 CCDC106 coiled-coil domain containing 106 1 1
MIRT054493 EEF1A2 eukaryotic translation elongation factor 1 alpha 2 3 1
MIRT451195 PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 2 2
MIRT452931 DISC1 disrupted in schizophrenia 1 2 2
MIRT455468 LYPLA2 lysophospholipase II 2 2
MIRT457068 TOR4A torsin family 4 member A 2 2
MIRT464195 VGLL4 vestigial like family member 4 2 4
MIRT483030 KHSRP KH-type splicing regulatory protein 2 4
MIRT486062 CTDNEP1 CTD nuclear envelope phosphatase 1 2 2
MIRT486120 INO80E INO80 complex subunit E 2 2
MIRT486866 DPF1 double PHD fingers 1 2 2
MIRT488343 PAX2 paired box 2 2 2
MIRT488790 POFUT2 protein O-fucosyltransferase 2 2 2
MIRT490249 MFI2 melanotransferrin 2 2
MIRT490264 HAAO 3-hydroxyanthranilate 3,4-dioxygenase 2 2
MIRT490756 SRCIN1 SRC kinase signaling inhibitor 1 2 2
MIRT492321 SETD1B SET domain containing 1B 2 2
MIRT492851 NRGN neurogranin 2 2
MIRT499604 ANKRD45 ankyrin repeat domain 45 2 2
MIRT500189 BARX1 BARX homeobox 1 2 4
MIRT516765 FAM212B family with sequence similarity 212 member B 2 4
MIRT517949 TRIM59 tripartite motif containing 59 2 2
MIRT521182 SCAF4 SR-related CTD associated factor 4 2 2
MIRT526462 OSBPL5 oxysterol binding protein like 5 2 2
MIRT535148 PLEKHG5 pleckstrin homology and RhoGEF domain containing G5 2 2
MIRT569528 AP5Z1 adaptor related protein complex 5 zeta 1 subunit 2 2
MIRT570593 NFIX nuclear factor I X 2 2
MIRT571219 F2R coagulation factor II thrombin receptor 2 2
MIRT574145 MARVELD1 MARVEL domain containing 1 2 2
MIRT608758 CACNA1A calcium voltage-gated channel subunit alpha1 A 2 2
MIRT649509 RAB17 RAB17, member RAS oncogene family 2 2
MIRT692165 RNF207 ring finger protein 207 2 2
MIRT703495 FNDC3B fibronectin type III domain containing 3B 2 2
MIRT711081 NEUROD2 neuronal differentiation 2 2 2
MIRT712090 UNC13A unc-13 homolog A 2 2
MIRT712531 CYTH2 cytohesin 2 2 2
MIRT712755 GMDS GDP-mannose 4,6-dehydratase 2 2
MIRT712893 TGFA transforming growth factor alpha 2 2
MIRT714684 PRX periaxin 2 2
MIRT714723 VPS8 VPS8, CORVET complex subunit 2 2
MIRT714814 NOB1 NIN1/PSMD8 binding protein 1 homolog 2 2
MIRT716774 C1orf229 chromosome 1 open reading frame 229 2 2
MIRT717511 HRNR hornerin 2 2
MIRT717653 THBS2 thrombospondin 2 2 2
MIRT719595 PIAS4 protein inhibitor of activated STAT 4 2 2
MIRT720525 PTGR2 prostaglandin reductase 2 2 2
MIRT724925 VPS18 VPS18, CORVET/HOPS core subunit 2 2
MIRT737146 NOS3 nitric oxide synthase 3 1 0
MIRT756003 SLC7A5 solute carrier family 7 member 5 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-744 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 down-regulated
miR-744 Tert-butyl hydroperoxide (t-BHP) NULL 6410 Microarray mouse auditory cells 20510889 2010 up-regulated
miR-744 Ursodeoxycholic acid (UDCA) approved 31401 Microarray rat Liver 20689055 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-744 Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (SGC-7901)
hsa-mir-744 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-744 Androstenedione 6128 NSC9563 sensitive cell line (MCF-7)
hsa-mir-744 Fluorouracil 3385 NSC19893 approved resistant cell line (OE19)
hsa-mir-744 Fluorouracil 3385 NSC19893 approved resistant cell line (KYSE)
hsa-mir-744 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-mir-744 Cisplatin 5460033 NSC119875 approved resistant cell line (SGC-7901)
hsa-miR-744-5p [1,1'-binaphthalene]-2,2',3,3'-tetrol 316673 NSC245006 sensitive
hsa-miR-744-5p 4-n-[12-[(5-amino-6-chloropyrimidin-4-yl)amino]dodecyl]-6-chloropyrimidine-4,5-diamine 358989 NSC619196 sensitive
hsa-miR-744-5p 5,7-dibromo-2-[(e)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]quinolin-8-ol 135460261 NSC67090 sensitive
hsa-miR-744-5p Benzyl 2-(dibenzylamino)-3-phenylpropanoate 375616 NSC655438 sensitive
hsa-miR-744-5p N'-[(Z)-[(4Z)-2-(1,3-benzodioxol-5-yl)-4-[[4-oxo-4-[2-(trifluoromethyl)anilino]butanoyl]hydrazinylidene]chromen-3-ylidene]amino]-N-[2-(trifluoromethyl)phenyl]butanediamide 6399328 NSC641210 sensitive
hsa-miR-744-5p Paullone analog 47 396411 NSC702373 sensitive
hsa-miR-744-5p Ursa-11,13(18)-dien-28-oic acid-3.beta.-ol 378695 NSC661747 sensitive
hsa-miR-744-5p Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7, LY2)
hsa-miR-744-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (SKOV3)
hsa-miR-744-5p Carboplatin 38904 NSC241240 approved sensitive High Ovarian Cancer tissue and cell line (MDAH-2274, SKOV3)
hsa-miR-744-5p Gefitinib 123631 NSC715055 approved resistant High Lung Adenocarcinoma cell line (A549)
hsa-miR-744-5p Cisplatin 5460033 NSC119875 approved sensitive High Esophageal Squamous Cell Carcinoma cell line (KYSE410)
hsa-miR-744-5p Tamoxifen 2733525 NSC180973 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-744-5p Cisplatin 5460033 NSC119875 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-744-5p Vinorelbine 44424639 approved resistant High Breast Cancer cell line (MDA-MB-231)
hsa-miR-744-5p Epirubicin 41867 NSC256942 approved resistant High Breast Cancer cell line (MDA-MB-231)
hsa-miR-744-5p Erlotinib 176870 NSC718781 approved sensitive High Non-Small Cell Lung Cancer tissue
hsa-miR-744-5p Gefitinib 123631 NSC715055 approved sensitive High Non-Small Cell Lung Cancer tissue
hsa-miR-744-5p Sunitinib 5329102 NSC750690 approved sensitive High Renal Cell Cancer tissue
hsa-miR-744-5p Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (AsPC-1)
hsa-miR-744-5p Sorafenib 216239 NSC747971 approved sensitive Low Hepatocellular Carcinoma cell line (HepG2)
hsa-miR-744-5p Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (SGC-7901, BGC-823)
hsa-miR-744-5p Oxaliplatin 6857599 NSC266046 approved resistant Low Colorectal Cancer cell line (HCT-116)
hsa-miR-744-5p Bortezomib 387447 NSC681239 approved sensitive Low Multiple Myeloma tissue
hsa-miR-744-5p Cisplatin 5460033 NSC119875 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-744-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-744-5p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-744-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (CAL-27) (cytosolic RNA)
hsa-miR-744-5p Doxorubicin 31703 NSC123127 approved sensitive cell line (HS578T)
hsa-miR-744-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-744-5p Fluorouracil 3385 NSC19893 approved sensitive cell line (HCT15)
hsa-miR-744-5p 4-Hydroxytamoxifen+Tamoxifen sensitive cell line (LY2)
hsa-miR-744-5p Ethanol+Tamoxifen sensitive cell line (LY2)
hsa-miR-744-5p Methotrexate 126941 NSC740 approved resistant cell line (HT29)
hsa-miR-744-5p Fluorouracil 3385 NSC19893 approved resistant cell line (KM12C) (72 h)
hsa-miR-744-5p Cisplatin 5460033 NSC119875 approved resistant cell line (RPMI2650)
hsa-miR-744-5p Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-miR-744-5p Gemcitabine 60750 NSC613327 approved resistant cell line (MDA-231)
hsa-miR-744-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (PC3PR20)
hsa-miR-744-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-744-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-744-5p Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)
hsa-miR-744-5p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-744-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (H23)

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