miRTarBase - #MIRT038287


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pre-miRNA Information
pre-miRNA hsa-mir-130b   
Genomic Coordinates chr22: 21653304 - 21653385
Synonyms MIRN130B, mir-130b, MIR130B
Description Homo sapiens miR-130b stem-loop
Comment This sequence is the predicted human homologue of mouse miR-130b cloned from mouse embryonic stem cells .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-130b-5p
Sequence 13| ACUCUUUCCCUGUUGCACUAC |33
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 1 22 + 21653316 18684997, 29233923 MiREDiBase
A-to-I 20 22 + 21653335 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs774584516 1 dbSNP
rs1174814901 2 dbSNP
rs761813865 7 dbSNP
rs1414195475 8 dbSNP
rs1435758272 12 dbSNP
rs767568985 16 dbSNP
rs1371968909 20 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol DDX3X   
Synonyms CAP-Rf, DBX, DDX14, DDX3, HLP2, MRX102
Description DEAD-box helicase 3, X-linked
Transcript NM_001356   
Expression
Putative miRNA Targets on DDX3X
3'UTR of DDX3X
(miRNA target sites are highlighted)		 
>DDX3X|NM_001356|3'UTR
   1 GCCTGCTTTGCAGTAGGTCACCCTGCCAAACAAGCTAATATGGAAACCACATGTAACTTAGCCAGACTATACCTTGTGTA
  81 GCTTCAAGAACTCGCAGTACATTACCAGCTGTGATTCTCCACTGAAATTTTTTTTTTAAGGGAGCTCAAGGTCACAAGAA
 161 GAAATGAAAGGAACAATCAGCAGCCCTGTTCAGAAGGTGGTTTGAAGACTTCATTGCTGTAGTTTGGATTAACTCCCCTC
 241 CCGCCTACCCCCATCCCAAACTGCATTTATAATTTTGTGACTGAGGATCATTTGTTTGTTAATGTACTGTGCCTTTAACT
 321 TTAGACAACTTTTTATTTTGATGTCCTGTTGGCTCAGTAATGCTCAAGATATCAATTGTTTTGACAAAATAAATTTACTG
 401 AACTTGGGCTAAAATCAAACCTTGGCACACAGGTGTGATACAACTTAACAGGAATCATCGATTCATCCATAAATAATATA
 481 AGGAAAAACTTATGCGGTAGCCTGCATTAGGGCTTTTTGATACTTGCAGATTGGGGGAAAACAACAAATGTCTTGAAGCA
 561 TATTAATGGAATTAGTTTCTAATGTGGCAAACTGTATTAAGTTAAAGTTCTGATTTGCTCACTCTATCCTGGATAGGTAT
 641 TTAGAACCTGATAGTCTTTAAGCCATTCCAGTCATGATGAGGTGATGTATGAATACATGCATACATTCAAAGCACTGTTT
 721 TCAAAGTTAATGCAAGTAAATACAGCAATTCCTCTTTCAACGTTTAGGCAGATCATTAATTATGAGCTAGCCAAATGTGG
 801 GCATACTATTACAGGGAAAGTTTAAAGGTCTGATAACTTGAAATAGGTTTTTAGGAGAATTCATCTACTTAGACTTTTTA
 881 AATGCCTGCCATAAATGAAATTGAAATGGTAGAATGGCTGACCACAGCAATGACCAGCCCTCATTAGGGCCCTGGATGAT
 961 TTTTGGTCTAATAACGCATGCTAGTGTTGATGTTTTTTGGTCAAGAGGGTATGAACAGGAAGAATTAAATGCAGCAGGCT
1041 TTATTTTAAATGCCGATTCACATTACTCTGTTCAAGCTGCGTTGAGATGTTAAACTGGCTTACTATAGACTTCGTAAAAA
1121 TGGCTCCAGAAGAGTAACAAACTGAAATCTTTGAGATCACACAGGTTGGAAATATGTACATAACTGCACAAGGTGTCAAT
1201 TCTGCTCTACAGTGCAGTTTTAGTCAGTTTTAGTTGCATAGGTTTCCATTGTATTTATAGTCTGTTTATGCTAAATCTGG
1281 CCAAAGATGAGCATTGTCCACCACTAAAATGCCTCTGCCACTTTGAATTCTGTGCTAATTTTGTGGCCAGAATGCGGTGA
1361 TCAAAACGCTCCATCTTTTTACAGTGGCATAGGAAGACGGCAAAAATTTCCTAAAGTGCAATAGATTTTCAAGTGTATTG
1441 TGCCTTGTTCTAAAACTTTTATTAAGTAGGTGCACTTGACAGTATTGAGGTCATTTGTTATGGTGCTATTTCAATTAGTC
1521 TAGGTTTAGGCCCTTGTACATTTTGCCCATAACTTTTTACAAAGTACTTCTTTTATTGCACATTCAGAGAATTTTATATA
1601 TATGTCTTGTGTGCGTGTCCTTAAACTTCCAATCTTACTTTGTCTCTTGGAGATTGTTGAACGCAGCTTGTCTAGGAAGG
1681 GGATGGGACTAGATTCTAAAATTTATTTGGGACCATGGGAATGATAGTTGGGAAGAAAACTATTTGCACACGACAGATTT
1761 CTAGATACTTTTTGCTGCTAGTTTTATGTAATATTTATTGAACATTTTGACAAATATTTATTTTTGTAAGCCTAAAAGTG
1841 ATTCTTTGAAAGTTTAAAGAAACTTGACCAAAAGACAGTACAAAAACACTGGCACTTGAATGTTGAATGTCACCGTATGC
1921 GTGAAATTATATATTTCGGGGTAGTGTGAGCTTTTAATGTTTAAGTCATATTAAACTCTTAAGTCAAATTAAGCAGACCC
2001 GGCGTTGGCAGTGTAGCCATAACTTTCTGATGTTAGTAAAAACAAAATTGGCGACTTGAAATTAAATCATGCCAAGGTTT
2081 TGATACACTTGTCTTAAGATATTAATGAAACACTTCAAAACACTGATGTGAAGTGTCCAGATTCTCAGATGTTTGTTGTG
2161 TGGATTTTGTTTAGTTGTGTGTTTTTTTTTTTTTTTCAGTGAATGTCTGGCACATTGCAATCCTCAAACATGTGGTTATC
2241 TTTGTTGTATTGGCATAATCAGTGACTTGTACATTCAGCAATAGCATTTGAGCAAGTTTTATCAGCAAGCAATATTTTCA
2321 GTTAATAAGGTTTCAAAAATCATGTAAGGATTTAAACTTGCTGAATGTAAAGATTGAACCTCAAGTCACTGTAGCTTTAG
2401 TAATTGCTTATTGTATTAGTTTAGATGCTAGCACTGCATGTGCTGTGCATATTCTGATTTTATTAAAATAAAAAGTTGAA
2481 CTGCACAGTCTCCTTTGTTGTTGTCAATTGTGGTTTATTTTCAGAGGTGTAAATAAAGTGCTCTTGCCTGAAAAATTGTA
2561 AAATGTTAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' caUCACGUUGUCCCUUUCuca 5'
            | | : ||||||||||   
Target 5' atACTATTACAGGGAAAGttt 3'
 803 - 823 127.00 -15.12
2 
miRNA  3' caUCACGUUGUCCCUUUCUca 5'
            ||||  :||  |:||||  
Target 5' acAGTG--GCATAGGAAGAcg 3'
 1381 - 1399 119.00 -9.50
3 
miRNA  3' caucacGUUGUC--CCUUUCUca 5'
                ::|:||  ||:||||  
Target 5' tgggaaTGATAGTTGGGAAGAaa 3'
 1716 - 1738 117.00 -8.00
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs761187616 2 dbSNP
rs746863718 3 dbSNP
rs768473702 4 dbSNP
rs776609516 7 dbSNP
rs1204081529 8 dbSNP
rs1348074660 14 dbSNP
rs748100931 21 dbSNP
rs769230915 22 dbSNP
rs1236954563 23 dbSNP
rs772742027 24 dbSNP
rs762467559 29 dbSNP
rs1349058942 32 dbSNP
rs1424227581 40 dbSNP
rs766101073 42 dbSNP
rs972463796 52 dbSNP
rs1169127900 54 dbSNP
rs754064835 56 dbSNP
rs952501851 81 dbSNP
rs1328229472 94 dbSNP
rs985040046 95 dbSNP
rs755187450 96 dbSNP
rs1383054324 102 dbSNP
rs1175831941 107 dbSNP
rs943507901 118 dbSNP
rs1300181162 127 dbSNP
rs1171639212 128 dbSNP
rs962482657 128 dbSNP
rs1242684681 138 dbSNP
rs1388757094 139 dbSNP
rs1191831062 147 dbSNP
rs1039183098 151 dbSNP
rs778745778 152 dbSNP
rs1259101086 161 dbSNP
rs923443460 162 dbSNP
rs933365420 165 dbSNP
rs764539353 166 dbSNP
rs1280101517 175 dbSNP
rs1053633235 177 dbSNP
rs1347355771 192 dbSNP
rs1342056503 197 dbSNP
rs939247104 198 dbSNP
rs1216762770 221 dbSNP
rs992871072 223 dbSNP
rs754205996 230 dbSNP
rs1415649893 241 dbSNP
rs1205924505 243 dbSNP
rs1012020929 244 dbSNP
rs372583916 252 dbSNP
rs1167270173 258 dbSNP
rs1474110199 277 dbSNP
rs1419423041 290 dbSNP
rs1041784596 291 dbSNP
rs1209653125 316 dbSNP
rs1485120176 323 dbSNP
rs905828369 329 dbSNP
rs1208440542 336 dbSNP
rs936191108 373 dbSNP
rs1001408656 374 dbSNP
rs141148280 384 dbSNP
rs1316089939 386 dbSNP
rs1295171475 399 dbSNP
rs1234032480 406 dbSNP
rs1355048552 410 dbSNP
rs1423538754 415 dbSNP
rs1478190157 436 dbSNP
rs1282711044 441 dbSNP
rs1172545984 445 dbSNP
rs1366957515 446 dbSNP
rs1039895211 453 dbSNP
rs1035452036 459 dbSNP
rs998833215 460 dbSNP
rs750738573 461 dbSNP
rs1056357 466 dbSNP
rs993854773 470 dbSNP
rs747950068 479 dbSNP
rs952397173 480 dbSNP
rs1204392224 481 dbSNP
rs1397898932 484 dbSNP
rs1456807873 487 dbSNP
rs1297512247 490 dbSNP
rs1275665342 494 dbSNP
rs1340989779 496 dbSNP
rs984225088 497 dbSNP
rs191078702 502 dbSNP
rs1225710948 503 dbSNP
rs183543802 516 dbSNP
rs1215839614 521 dbSNP
rs1309911956 524 dbSNP
rs1278700251 528 dbSNP
rs772040867 538 dbSNP
rs773176719 540 dbSNP
rs964925651 545 dbSNP
rs975005455 556 dbSNP
rs1460405668 580 dbSNP
rs1033916495 584 dbSNP
rs1160780260 585 dbSNP
rs777617499 587 dbSNP
rs960671126 591 dbSNP
rs1406857452 593 dbSNP
rs1178397139 595 dbSNP
rs1438303306 596 dbSNP
rs1255370095 598 dbSNP
rs747067311 599 dbSNP
rs1194820364 600 dbSNP
rs1468053596 602 dbSNP
rs1245093163 625 dbSNP
rs1218093395 634 dbSNP
rs992462951 642 dbSNP
rs12838867 647 dbSNP
rs1283892673 649 dbSNP
rs1237677834 659 dbSNP
rs923410846 660 dbSNP
rs917260646 666 dbSNP
rs933499622 675 dbSNP
rs945996989 682 dbSNP
rs28364818 693 dbSNP
rs977414349 695 dbSNP
rs1056358 714 dbSNP
rs1364826739 717 dbSNP
rs775642389 718 dbSNP
rs754909334 720 dbSNP
rs189047420 722 dbSNP
rs1161240185 733 dbSNP
rs913342647 741 dbSNP
rs1344233505 744 dbSNP
rs192439219 746 dbSNP
rs1418196022 749 dbSNP
rs770374177 750 dbSNP
rs1174774836 758 dbSNP
rs370210510 759 dbSNP
rs150291427 761 dbSNP
rs937228791 762 dbSNP
rs1188388874 770 dbSNP
rs1262661204 775 dbSNP
rs1056992853 776 dbSNP
rs1486500970 781 dbSNP
rs759161501 784 dbSNP
rs1280820902 809 dbSNP
rs1254214422 811 dbSNP
rs1233343628 812 dbSNP
rs1423294486 814 dbSNP
rs1164511172 818 dbSNP
rs994435964 821 dbSNP
rs1214578256 829 dbSNP
rs770595846 831 dbSNP
rs769385297 833 dbSNP
rs772848431 838 dbSNP
rs934261141 841 dbSNP
rs1416281268 842 dbSNP
rs1051748158 847 dbSNP
rs1313850389 849 dbSNP
rs774766683 869 dbSNP
rs776206800 880 dbSNP
rs1003873359 887 dbSNP
rs1429134732 898 dbSNP
rs1361127563 904 dbSNP
rs1432857432 929 dbSNP
rs1037982553 936 dbSNP
rs1191726249 941 dbSNP
rs1476291761 944 dbSNP
rs1258545901 946 dbSNP
rs1199657920 949 dbSNP
rs898278507 969 dbSNP
rs1252943624 976 dbSNP
rs1001879814 977 dbSNP
rs1300989799 982 dbSNP
rs1306376509 988 dbSNP
rs1275726222 1007 dbSNP
rs184422133 1020 dbSNP
rs1355677530 1029 dbSNP
rs1292364226 1035 dbSNP
rs770503392 1036 dbSNP
rs1395739193 1053 dbSNP
rs1400529378 1053 dbSNP
rs188053707 1055 dbSNP
rs1462971011 1056 dbSNP
rs1400264049 1059 dbSNP
rs1168594661 1063 dbSNP
rs1316727676 1065 dbSNP
rs1418762091 1066 dbSNP
rs758990835 1066 dbSNP
rs1350972903 1076 dbSNP
rs764675036 1082 dbSNP
rs1421784852 1107 dbSNP
rs1252448891 1111 dbSNP
rs966617551 1114 dbSNP
rs1238454753 1118 dbSNP
rs1457248666 1125 dbSNP
rs1256149144 1132 dbSNP
rs977445435 1141 dbSNP
rs1215008588 1143 dbSNP
rs925932716 1154 dbSNP
rs1264435519 1155 dbSNP
rs1285703279 1156 dbSNP
rs1317862541 1158 dbSNP
rs1218617373 1162 dbSNP
rs1271314799 1163 dbSNP
rs1339031638 1164 dbSNP
rs957456713 1176 dbSNP
rs1236216499 1181 dbSNP
rs750904417 1188 dbSNP
rs761286900 1200 dbSNP
rs921448167 1202 dbSNP
rs777316498 1203 dbSNP
rs144966805 1210 dbSNP
rs1159553230 1212 dbSNP
rs1051267844 1214 dbSNP
rs773809766 1215 dbSNP
rs1195434209 1222 dbSNP
rs908822334 1227 dbSNP
rs1266088065 1243 dbSNP
rs1207592176 1249 dbSNP
rs940263723 1258 dbSNP
rs1261007980 1263 dbSNP
rs764737853 1263 dbSNP
rs752012524 1265 dbSNP
rs1402223957 1266 dbSNP
rs1038012318 1269 dbSNP
rs1477104618 1279 dbSNP
rs1443796906 1287 dbSNP
rs762261667 1289 dbSNP
rs1322951376 1291 dbSNP
rs1385223672 1306 dbSNP
rs1387415525 1316 dbSNP
rs1289675436 1322 dbSNP
rs1001964578 1325 dbSNP
rs766527316 1332 dbSNP
rs1378279923 1338 dbSNP
rs5963957 1339 dbSNP
rs1338065735 1344 dbSNP
rs750762642 1348 dbSNP
rs1377052415 1350 dbSNP
rs1445631205 1354 dbSNP
rs755214981 1357 dbSNP
rs896229208 1358 dbSNP
rs765441946 1363 dbSNP
rs1013879402 1364 dbSNP
rs763165535 1369 dbSNP
rs1277123651 1372 dbSNP
rs1284281935 1389 dbSNP
rs1237018292 1390 dbSNP
rs1312074178 1393 dbSNP
rs1346307635 1399 dbSNP
rs966648040 1400 dbSNP
rs1328293693 1404 dbSNP
rs1204422229 1430 dbSNP
rs768052807 1455 dbSNP
rs1399665379 1456 dbSNP
rs1265125033 1457 dbSNP
rs750774419 1459 dbSNP
rs1033012566 1460 dbSNP
rs1435167324 1461 dbSNP
rs1401404636 1462 dbSNP
rs957322741 1467 dbSNP
rs1476080456 1476 dbSNP
rs1198318500 1483 dbSNP
rs1233665628 1488 dbSNP
rs766544623 1515 dbSNP
rs1476621875 1516 dbSNP
rs1471044263 1521 dbSNP
rs1259249406 1523 dbSNP
rs1213454767 1530 dbSNP
rs975429362 1532 dbSNP
rs1278470517 1558 dbSNP
rs1189189198 1562 dbSNP
rs1424396370 1563 dbSNP
rs1341516122 1565 dbSNP
rs1480697833 1565 dbSNP
rs1178458916 1570 dbSNP
rs1218146846 1586 dbSNP
rs780315155 1589 dbSNP
rs1295422189 1590 dbSNP
rs1397559593 1595 dbSNP
rs1464635469 1598 dbSNP
rs921385613 1601 dbSNP
rs1329207075 1603 dbSNP
rs955465927 1603 dbSNP
rs1355852126 1604 dbSNP
rs987403766 1607 dbSNP
rs191556194 1609 dbSNP
rs1273403070 1610 dbSNP
rs1169323377 1611 dbSNP
rs1367309661 1616 dbSNP
rs1419480709 1617 dbSNP
rs908687069 1631 dbSNP
rs1473304674 1634 dbSNP
rs1224718275 1639 dbSNP
rs1285739322 1647 dbSNP
rs940294830 1649 dbSNP
rs755064861 1657 dbSNP
rs1259335126 1663 dbSNP
rs1198019387 1671 dbSNP
rs1273994778 1684 dbSNP
rs1275228800 1694 dbSNP
rs1439722700 1698 dbSNP
rs758067575 1715 dbSNP
rs781079886 1739 dbSNP
rs752699164 1741 dbSNP
rs1219142762 1743 dbSNP
rs1282187881 1744 dbSNP
rs755892218 1746 dbSNP
rs937707942 1747 dbSNP
rs1054796685 1748 dbSNP
rs1421382643 1751 dbSNP
rs1477212035 1752 dbSNP
rs1396065129 1757 dbSNP
rs754009150 1767 dbSNP
rs896250715 1769 dbSNP
rs949152601 1814 dbSNP
rs1161816279 1815 dbSNP
rs1411247556 1815 dbSNP
rs1442006822 1837 dbSNP
rs1167931443 1856 dbSNP
rs1421246939 1875 dbSNP
rs1042259619 1897 dbSNP
rs746905097 1908 dbSNP
rs1456468480 1921 dbSNP
rs1254933570 1926 dbSNP
rs1403287060 1930 dbSNP
rs902325961 1932 dbSNP
rs1288068646 1938 dbSNP
rs1225189619 1939 dbSNP
rs1354161625 1946 dbSNP
rs757222373 1963 dbSNP
rs1032293764 1965 dbSNP
rs1293584333 1979 dbSNP
rs1373154570 1979 dbSNP
rs1435205657 1993 dbSNP
rs780661126 2005 dbSNP
rs1219175866 2014 dbSNP
rs143157550 2023 dbSNP
rs1319885604 2024 dbSNP
rs1421844874 2027 dbSNP
rs1365411949 2032 dbSNP
rs1405933685 2034 dbSNP
rs997275515 2050 dbSNP
rs1028310821 2051 dbSNP
rs745431132 2053 dbSNP
rs1427934263 2054 dbSNP
rs1191839083 2084 dbSNP
rs1488198721 2087 dbSNP
rs749041943 2088 dbSNP
rs184335138 2100 dbSNP
rs986879731 2106 dbSNP
rs1226808944 2111 dbSNP
rs1285010983 2118 dbSNP
rs1270808165 2119 dbSNP
rs1349952545 2129 dbSNP
rs1301978236 2138 dbSNP
rs1218060905 2139 dbSNP
rs1341527904 2140 dbSNP
rs1015716120 2144 dbSNP
rs778479330 2153 dbSNP
rs974204784 2154 dbSNP
rs879175688 2155 dbSNP
rs920217454 2161 dbSNP
rs1224354767 2169 dbSNP
rs1260954973 2173 dbSNP
rs1177439884 2174 dbSNP
rs1423187461 2176 dbSNP
rs1425058200 2176 dbSNP
rs1432613395 2176 dbSNP
rs1478259866 2180 dbSNP
rs1487898852 2180 dbSNP
rs1193769456 2181 dbSNP
rs1275915491 2182 dbSNP
rs1304619885 2182 dbSNP
rs1339439427 2182 dbSNP
rs1491236593 2182 dbSNP
rs201921813 2182 dbSNP
rs745349949 2182 dbSNP
rs745437857 2182 dbSNP
rs1398473587 2183 dbSNP
rs201313897 2183 dbSNP
rs771773583 2184 dbSNP
rs1465956341 2185 dbSNP
rs1471514984 2187 dbSNP
rs1172895256 2196 dbSNP
rs1162351215 2197 dbSNP
rs866735665 2198 dbSNP
rs769484966 2199 dbSNP
rs1165804525 2201 dbSNP
rs188774286 2204 dbSNP
rs1425284066 2214 dbSNP
rs1256634640 2217 dbSNP
rs1359224895 2221 dbSNP
rs1382198766 2230 dbSNP
rs1240020679 2240 dbSNP
rs1198652508 2245 dbSNP
rs762349811 2267 dbSNP
rs181503639 2270 dbSNP
rs1445909834 2272 dbSNP
rs1321986986 2279 dbSNP
rs772277504 2291 dbSNP
rs917563452 2296 dbSNP
rs1333959339 2300 dbSNP
rs1314639250 2303 dbSNP
rs1383729009 2304 dbSNP
rs14554 2313 dbSNP
rs1283670483 2323 dbSNP
rs1369328336 2334 dbSNP
rs949178489 2339 dbSNP
rs1421837483 2340 dbSNP
rs1205703952 2342 dbSNP
rs1042124013 2367 dbSNP
rs902255490 2369 dbSNP
rs773582897 2373 dbSNP
rs1456898193 2376 dbSNP
rs763252865 2381 dbSNP
rs708452 2389 dbSNP
rs1211169031 2390 dbSNP
rs1488597996 2390 dbSNP
rs766604206 2392 dbSNP
rs751771731 2409 dbSNP
rs1244440369 2411 dbSNP
rs1053597919 2412 dbSNP
rs1243394799 2416 dbSNP
rs1312039890 2424 dbSNP
rs1064198 2434 dbSNP
rs900446674 2446 dbSNP
rs996079824 2448 dbSNP
rs3209046 2455 dbSNP
rs1329380276 2464 dbSNP
rs878952279 2467 dbSNP
rs1388665300 2470 dbSNP
rs1391636539 2471 dbSNP
rs1446035893 2473 dbSNP
rs1028759725 2475 dbSNP
rs1456150414 2475 dbSNP
rs1381971534 2481 dbSNP
rs1438979404 2484 dbSNP
rs185737091 2484 dbSNP
rs767643733 2487 dbSNP
rs1200372174 2493 dbSNP
rs1378471289 2493 dbSNP
rs1433273788 2494 dbSNP
rs1266159951 2495 dbSNP
rs752787065 2495 dbSNP
rs1489950380 2497 dbSNP
rs1378910915 2501 dbSNP
rs1288563214 2503 dbSNP
rs891087653 2510 dbSNP
rs1008275330 2511 dbSNP
rs1015666690 2518 dbSNP
rs961438951 2530 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Flp-In T-REx 293-hAGO1 cells
Location of target site 3'UTR
Original Description (Extracted from the article) ... Validation of interactions identified by CLASH suppports their reliability. ...

- Helwak A; Kudla G; Dudnakova T; Tollervey D, 2013, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' caUCACGUUGUCCCUUUCuca 5'
            | | : ||||||||||   
Target 5' --ACTATTACAGGGAAAGttt 3'
 		1 - 19
2 
miRNA  3' caUCACGUUGU--CCCUUUCUCa 5'
            :|| ::|:|    |||| || 
Target 5' aaGGTCTGATAACTTGAAATAGg 3'
 		21 - 43
Article - Helwak A; Kudla G; Dudnakova T; Tollervey D
- Cell, 2013
MicroRNAs (miRNAs) play key roles in gene regulation, but reliable bioinformatic or experimental identification of their targets remains difficult. To provide an unbiased view of human miRNA targets, we developed a technique for ligation and sequencing of miRNA-target RNA duplexes associated with human AGO1. Here, we report data sets of more than 18,000 high-confidence miRNA-mRNA interactions. The binding of most miRNAs includes the 5' seed region, but around 60% of seed interactions are noncanonical, containing bulged or mismatched nucleotides. Moreover, seed interactions are generally accompanied by specific, nonseed base pairing. 18% of miRNA-mRNA interactions involve the miRNA 3' end, with little evidence for 5' contacts, and some of these were functionally validated. Analyses of miRNA:mRNA base pairing showed that miRNA species systematically differ in their target RNA interactions, and strongly overrepresented motifs were found in the interaction sites of several miRNAs. We speculate that these affect the response of RISC to miRNA-target binding.
LinkOut: [PMID: 23622248]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28260 Renal cortex and medulla 0.716 3.0e-3 0.791 6.4e-4 13 Click to see details
GSE19350 CNS germ cell tumors -0.667 8.9e-3 -0.497 5.0e-2 12 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.805 1.4e-2 0.857 6.9e-3 7 Click to see details
GSE19783 ER+ ER+ breast cancer -0.422 3.2e-2 -0.429 3.0e-2 20 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.318 6.1e-2 -0.315 6.3e-2 25 Click to see details
GSE19783 ER- ER- breast cancer -0.161 7.8e-2 -0.146 1.0e-1 79 Click to see details
GSE38226 Liver fibrosis -0.303 9.1e-2 -0.346 6.2e-2 21 Click to see details
GSE19536 Breast cancer -0.13 9.9e-2 -0.108 1.4e-1 100 Click to see details
GSE21687 Ependynoma primary tumors -0.163 9.9e-2 -0.104 2.1e-1 64 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.276 1.2e-1 0.641 1.2e-3 20 Click to see details
GSE42095 Differentiated embryonic stem cells -0.235 1.4e-1 -0.166 2.2e-1 23 Click to see details
GSE32688 Pancreatic cancer -0.153 2.0e-1 -0.121 2.5e-1 32 Click to see details
GSE28544 Breast cancer 0.159 2.3e-1 0.345 4.9e-2 24 Click to see details
GSE17498 Multiple myeloma 0.083 3.1e-1 0.136 2.0e-1 40 Click to see details
GSE35602 Colorectal cancer stromal tissue 0.077 3.6e-1 0.501 5.4e-3 25 Click to see details
GSE26953 Aortic valvular endothelial cells -0.013 4.8e-1 -0.091 3.4e-1 24 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
BRCA -0.206 0.03 -0.180 0.05 84 Click to see details
ESCA -0.554 0.04 -0.745 0 11 Click to see details
CESC -0.975 0.07 -0.500 0.33 3 Click to see details
COAD -0.567 0.07 -0.643 0.04 8 Click to see details
HNSC -0.153 0.17 -0.146 0.18 42 Click to see details
KIRC -0.111 0.18 -0.121 0.16 68 Click to see details
STAD -0.155 0.2 -0.160 0.19 31 Click to see details
KIRP -0.141 0.22 -0.280 0.06 32 Click to see details
CHOL 0.291 0.22 0.333 0.19 9 Click to see details
PCPG 0.72 0.24 1.000 0.5 3 Click to see details
LIHC 0.076 0.3 0.075 0.3 49 Click to see details
UCEC 0.107 0.33 0.247 0.15 19 Click to see details
KICH 0.078 0.36 0.088 0.34 25 Click to see details
LUAD -0.112 0.36 -0.329 0.15 12 Click to see details
PRAD -0.045 0.38 -0.052 0.36 50 Click to see details
BLCA -0.07 0.39 -0.027 0.46 17 Click to see details
PAAD -0.189 0.41 0.200 0.4 4 Click to see details
LUSC 0.036 0.42 0.007 0.48 38 Click to see details
THCA 0.023 0.43 0.073 0.29 59 Click to see details
THCA 0.023 0.43 0.073 0.29 59 Click to see details
THCA 0.023 0.43 0.073 0.29 59 Click to see details
337 hsa-miR-130b-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT038280 ASF1B anti-silencing function 1B histone chaperone 1 1
MIRT038281 MACC1 MACC1, MET transcriptional regulator 1 1
MIRT038282 ADPRHL2 ADP-ribosylhydrolase like 2 1 1
MIRT038283 MYBPC1 myosin binding protein C, slow type 1 1
MIRT038284 NCOR2 nuclear receptor corepressor 2 1 1
MIRT038285 DPYSL5 dihydropyrimidinase like 5 1 1
MIRT038286 EMC1 ER membrane protein complex subunit 1 1 1
MIRT038287 DDX3X DEAD-box helicase 3, X-linked 1 1
MIRT038288 CDC5L cell division cycle 5 like 1 1
MIRT038289 OGDHL oxoglutarate dehydrogenase like 1 1
MIRT038290 SRCAP Snf2 related CREBBP activator protein 1 1
MIRT038291 POLD3 DNA polymerase delta 3, accessory subunit 1 1
MIRT038292 PDS5A PDS5 cohesin associated factor A 1 1
MIRT038293 COX6B1 cytochrome c oxidase subunit 6B1 1 1
MIRT038294 COPB1 coatomer protein complex subunit beta 1 1 1
MIRT038295 BRAT1 BRCA1 associated ATM activator 1 1 1
MIRT038296 NOTCH2 notch 2 2 3
MIRT038297 RPL8 ribosomal protein L8 1 1
MIRT038298 HBS1L HBS1 like translational GTPase 1 1
MIRT038299 MFSD6 major facilitator superfamily domain containing 6 1 1
MIRT038300 SSH2 slingshot protein phosphatase 2 1 1
MIRT038301 PTPN11 protein tyrosine phosphatase, non-receptor type 11 1 1
MIRT038302 PAGR1 PAXIP1 associated glutamate rich protein 1 2 3
MIRT038303 ALDH1B1 aldehyde dehydrogenase 1 family member B1 1 1
MIRT038304 TTC3 tetratricopeptide repeat domain 3 1 1
MIRT038305 EP300 E1A binding protein p300 1 1
MIRT038306 PCDHGB4 protocadherin gamma subfamily B, 4 1 1
MIRT038307 CDC37L1 cell division cycle 37 like 1 1 1
MIRT038308 HELZ helicase with zinc finger 1 1
MIRT038309 JMY junction mediating and regulatory protein, p53 cofactor 1 1
MIRT038310 MEIS3 Meis homeobox 3 1 1
MIRT038311 SMG5 SMG5, nonsense mediated mRNA decay factor 1 1
MIRT038312 FAM72A family with sequence similarity 72 member A 1 1
MIRT038313 CGNL1 cingulin like 1 1 1
MIRT038314 HNRNPR heterogeneous nuclear ribonucleoprotein R 1 1
MIRT038315 WEE1 WEE1 G2 checkpoint kinase 1 1
MIRT038316 HSPA8 heat shock protein family A (Hsp70) member 8 1 1
MIRT038317 CHD1 chromodomain helicase DNA binding protein 1 1 1
MIRT038318 FASN fatty acid synthase 1 1
MIRT038319 PDHA1 pyruvate dehydrogenase E1 alpha 1 subunit 1 1
MIRT038320 DZIP3 DAZ interacting zinc finger protein 3 1 1
MIRT038321 CSE1L chromosome segregation 1 like 1 1
MIRT038322 VCL vinculin 1 1
MIRT038323 RNF10 ring finger protein 10 1 1
MIRT038324 AAMP angio associated migratory cell protein 1 1
MIRT038325 SMIM12 small integral membrane protein 12 1 1
MIRT038326 IKZF2 IKAROS family zinc finger 2 1 1
MIRT038327 RPL36AL ribosomal protein L36a like 1 1
MIRT038328 MID1 midline 1 1 1
MIRT038329 MTPN myotrophin 1 1
MIRT038330 ND6 NADH dehydrogenase, subunit 6 (complex I) 1 1
MIRT038331 HSPA1B heat shock protein family A (Hsp70) member 1B 1 1
MIRT038332 PSD3 pleckstrin and Sec7 domain containing 3 1 1
MIRT038333 TMEM167A transmembrane protein 167A 1 1
MIRT038334 SECISBP2 SECIS binding protein 2 1 1
MIRT038335 PTMA prothymosin, alpha 1 1
MIRT038336 PPP1R12C protein phosphatase 1 regulatory subunit 12C 1 1
MIRT097680 ARRDC3 arrestin domain containing 3 2 2
MIRT120585 ANKRD28 ankyrin repeat domain 28 2 2
MIRT134442 KDM5A lysine demethylase 5A 2 2
MIRT162005 TFRC transferrin receptor 2 2
MIRT211714 OTUD4 OTU deubiquitinase 4 2 4
MIRT287594 KANSL1 KAT8 regulatory NSL complex subunit 1 2 2
MIRT333938 TMCO1 transmembrane and coiled-coil domains 1 2 4
MIRT339811 ZIC5 Zic family member 5 2 2
MIRT370983 SCOC short coiled-coil protein 2 2
MIRT404962 COA4 cytochrome c oxidase assembly factor 4 homolog 2 2
MIRT442925 TFDP2 transcription factor Dp-2 2 2
MIRT444887 TMEM196 transmembrane protein 196 2 2
MIRT447218 ATXN7 ataxin 7 2 2
MIRT450592 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 2 2
MIRT450608 HLA-DOA major histocompatibility complex, class II, DO alpha 2 2
MIRT462474 FIZ1 FLT3 interacting zinc finger 1 2 2
MIRT471095 PIK3C2B phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta 2 2
MIRT471562 PATL1 PAT1 homolog 1, processing body mRNA decay factor 2 6
MIRT482059 ALG9 ALG9, alpha-1,2-mannosyltransferase 2 2
MIRT486040 UBBP4 ubiquitin B pseudogene 4 2 2
MIRT500478 ZC3H11A zinc finger CCCH-type containing 11A 2 2
MIRT500538 XPO4 exportin 4 2 2
MIRT505896 RIMS3 regulating synaptic membrane exocytosis 3 2 6
MIRT512067 DEK DEK proto-oncogene 2 6
MIRT512542 ZNF793 zinc finger protein 793 2 4
MIRT524872 ARID3A AT-rich interaction domain 3A 2 4
MIRT529391 NSFL1C NSFL1 cofactor 2 2
MIRT530542 SYNPO synaptopodin 2 2
MIRT533816 TIMM17A translocase of inner mitochondrial membrane 17A 2 6
MIRT536729 IGF1 insulin like growth factor 1 2 2
MIRT549717 NUP37 nucleoporin 37 2 2
MIRT550783 VAV3 vav guanine nucleotide exchange factor 3 2 2
MIRT551510 PLP1 proteolipid protein 1 2 2
MIRT553360 TRIM8 tripartite motif containing 8 2 2
MIRT555321 PPP2CB protein phosphatase 2 catalytic subunit beta 2 2
MIRT556293 MAP3K5 mitogen-activated protein kinase kinase kinase 5 2 2
MIRT556816 KIAA1161 myogenesis regulating glycosidase (putative) 2 4
MIRT558194 EIF2S1 eukaryotic translation initiation factor 2 subunit alpha 2 4
MIRT572484 PRR14L proline rich 14 like 2 2
MIRT607361 TNS1 tensin 1 2 6
MIRT609536 ADPRH ADP-ribosylarginine hydrolase 2 2
MIRT609689 EMX2 empty spiracles homeobox 2 2 2
MIRT609769 PLCL1 phospholipase C like 1 (inactive) 2 2
MIRT609846 ZNF557 zinc finger protein 557 2 2
MIRT611396 ATP9A ATPase phospholipid transporting 9A (putative) 2 2
MIRT611989 WDR59 WD repeat domain 59 2 2
MIRT612747 MYOCD myocardin 2 2
MIRT613417 GOSR2 golgi SNAP receptor complex member 2 2 4
MIRT613455 ZFX zinc finger protein, X-linked 2 2
MIRT613568 YY2 YY2 transcription factor 2 2
MIRT613694 QPRT quinolinate phosphoribosyltransferase 2 2
MIRT613740 GK5 glycerol kinase 5 (putative) 2 4
MIRT614178 FAM53B family with sequence similarity 53 member B 2 2
MIRT614195 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 2 2
MIRT614852 PLEKHA6 pleckstrin homology domain containing A6 2 2
MIRT615318 MLXIPL MLX interacting protein like 2 2
MIRT615683 NAV2 neuron navigator 2 2 2
MIRT615745 PRIM1 DNA primase subunit 1 2 2
MIRT615864 HSPA6 heat shock protein family A (Hsp70) member 6 2 2
MIRT615972 ASCL1 achaete-scute family bHLH transcription factor 1 2 2
MIRT617213 CERS4 ceramide synthase 4 2 2
MIRT617654 RWDD1 RWD domain containing 1 2 2
MIRT617762 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT618224 CST3 cystatin C 2 2
MIRT618405 AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 2 2
MIRT618610 SHOX short stature homeobox 2 2
MIRT618662 ATP6AP1L ATPase H+ transporting accessory protein 1 like 2 2
MIRT619266 QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 2 2
MIRT619363 CFHR5 complement factor H related 5 2 2
MIRT619924 NLRP9 NLR family pyrin domain containing 9 2 2
MIRT620138 ZNF283 zinc finger protein 283 2 2
MIRT620176 EGFLAM EGF like, fibronectin type III and laminin G domains 2 2
MIRT620366 CD55 CD55 molecule (Cromer blood group) 2 2
MIRT620637 RFT1 RFT1 homolog 2 2
MIRT620735 CCL16 C-C motif chemokine ligand 16 2 2
MIRT620846 ATG10 autophagy related 10 2 2
MIRT620904 MUT methylmalonyl-CoA mutase 2 2
MIRT621212 SULT1C4 sulfotransferase family 1C member 4 2 2
MIRT621842 TGFBR3 transforming growth factor beta receptor 3 2 2
MIRT622034 STAT5A signal transducer and activator of transcription 5A 2 2
MIRT622118 SPRY3 sprouty RTK signaling antagonist 3 2 2
MIRT622291 SH3PXD2A SH3 and PX domains 2A 2 2
MIRT622592 PRRG4 proline rich and Gla domain 4 2 4
MIRT622604 PROM1 prominin 1 2 2
MIRT622690 PLSCR1 phospholipid scramblase 1 2 2
MIRT622774 PGM2L1 phosphoglucomutase 2 like 1 2 2
MIRT622853 PDGFA platelet derived growth factor subunit A 2 2
MIRT623017 ONECUT3 one cut homeobox 3 2 2
MIRT623102 NLGN4X neuroligin 4, X-linked 2 2
MIRT623420 KMT2A lysine methyltransferase 2A 2 2
MIRT623423 KLHL28 kelch like family member 28 2 2
MIRT623535 KCNJ6 potassium voltage-gated channel subfamily J member 6 2 2
MIRT623958 FBXL16 F-box and leucine rich repeat protein 16 2 2
MIRT624042 ELAVL3 ELAV like RNA binding protein 3 2 2
MIRT624117 DNAH10OS dynein axonemal heavy chain 10 opposite strand 2 2
MIRT624147 DIAPH1 diaphanous related formin 1 2 2
MIRT624368 CDK12 cyclin dependent kinase 12 2 2
MIRT624408 CCDC171 coiled-coil domain containing 171 2 2
MIRT624459 CALCOCO2 calcium binding and coiled-coil domain 2 2 2
MIRT624854 ABI2 abl interactor 2 2 2
MIRT625452 RANGAP1 Ran GTPase activating protein 1 2 2
MIRT625938 SCYL3 SCY1 like pseudokinase 3 2 2
MIRT625949 OLIG3 oligodendrocyte transcription factor 3 2 2
MIRT626291 ZNF85 zinc finger protein 85 2 2
MIRT626907 NRN1 neuritin 1 2 2
MIRT627003 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT627031 TMEM109 transmembrane protein 109 2 2
MIRT628152 HIP1 huntingtin interacting protein 1 2 2
MIRT628990 PITPNM3 PITPNM family member 3 2 2
MIRT630432 LHX9 LIM homeobox 9 2 2
MIRT631541 AS3MT arsenite methyltransferase 2 2
MIRT635194 NFKBID NFKB inhibitor delta 2 2
MIRT635814 KCNK6 potassium two pore domain channel subfamily K member 6 2 2
MIRT636226 SLC5A12 solute carrier family 5 member 12 2 2
MIRT636304 PSMB5 proteasome subunit beta 5 2 2
MIRT636504 GDAP1L1 ganglioside induced differentiation associated protein 1 like 1 2 2
MIRT636830 FSIP2 fibrous sheath interacting protein 2 2 2
MIRT636857 ZSCAN2 zinc finger and SCAN domain containing 2 2 2
MIRT637017 TRABD2A TraB domain containing 2A 2 2
MIRT638338 RCAN1 regulator of calcineurin 1 2 2
MIRT638911 CBLN2 cerebellin 2 precursor 2 2
MIRT639353 TBXA2R thromboxane A2 receptor 2 2
MIRT639416 FAM26E calcium homeostasis modulator family member 5 2 4
MIRT639532 CD86 CD86 molecule 2 2
MIRT639805 AHCY adenosylhomocysteinase 2 2
MIRT640375 UQCRB ubiquinol-cytochrome c reductase binding protein 2 2
MIRT640605 PPARA peroxisome proliferator activated receptor alpha 2 2
MIRT641761 SF3A1 splicing factor 3a subunit 1 2 2
MIRT641794 USP32 ubiquitin specific peptidase 32 2 2
MIRT641879 SREK1 splicing regulatory glutamic acid and lysine rich protein 1 2 2
MIRT641987 OXSR1 oxidative stress responsive 1 2 2
MIRT642352 C19orf40 Fanconi anemia core complex associated protein 24 1 1
MIRT642469 RSL1D1 ribosomal L1 domain containing 1 2 2
MIRT642724 ATXN3 ataxin 3 2 2
MIRT642758 SDHAF2 succinate dehydrogenase complex assembly factor 2 2 2
MIRT642771 FAM9C family with sequence similarity 9 member C 2 2
MIRT643191 HYPK huntingtin interacting protein K 2 2
MIRT643244 PRSS21 protease, serine 21 2 2
MIRT643901 TCEB2 elongin B 2 2
MIRT643957 GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 2 2
MIRT644161 GIN1 gypsy retrotransposon integrase 1 2 2
MIRT644297 HRH1 histamine receptor H1 2 2
MIRT644374 ZNF286A zinc finger protein 286A 2 2
MIRT644407 FRMD6 FERM domain containing 6 2 2
MIRT644942 ATXN3L ataxin 3 like 2 2
MIRT645143 CUBN cubilin 2 2
MIRT645327 C9orf64 chromosome 9 open reading frame 64 2 2
MIRT645335 DHRS3 dehydrogenase/reductase 3 2 2
MIRT645469 SPIN3 spindlin family member 3 2 2
MIRT645496 TRIM63 tripartite motif containing 63 2 2
MIRT645921 PLXNA3 plexin A3 2 2
MIRT645955 TTF2 transcription termination factor 2 2 2
MIRT646031 S100A7A S100 calcium binding protein A7A 2 2
MIRT646208 DUSP10 dual specificity phosphatase 10 2 2
MIRT647166 TMLHE trimethyllysine hydroxylase, epsilon 2 2
MIRT647288 JAG2 jagged 2 2 2
MIRT647394 FAM181B family with sequence similarity 181 member B 2 2
MIRT647447 SIX6 SIX homeobox 6 2 2
MIRT647455 MC2R melanocortin 2 receptor 2 2
MIRT647616 IGSF9B immunoglobulin superfamily member 9B 2 2
MIRT648105 LRRFIP1 LRR binding FLII interacting protein 1 2 2
MIRT648358 AKIP1 A-kinase interacting protein 1 2 2
MIRT649541 VAMP8 vesicle associated membrane protein 8 2 2
MIRT650687 CD82 CD82 molecule 2 2
MIRT650707 KRT32 keratin 32 2 2
MIRT651055 ZNF579 zinc finger protein 579 2 2
MIRT651541 WNK1 WNK lysine deficient protein kinase 1 2 2
MIRT651588 WDR26 WD repeat domain 26 2 2
MIRT651634 WASF3 WAS protein family member 3 2 2
MIRT651739 VEGFB vascular endothelial growth factor B 2 2
MIRT651836 USP37 ubiquitin specific peptidase 37 2 2
MIRT652239 TRAPPC10 trafficking protein particle complex 10 2 2
MIRT652888 SYVN1 synoviolin 1 2 2
MIRT652897 SYT2 synaptotagmin 2 2 2
MIRT652937 SYNGR1 synaptogyrin 1 2 2
MIRT652963 SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 2 2
MIRT653469 SLC4A1 solute carrier family 4 member 1 (Diego blood group) 2 2
MIRT653580 SLC35B3 solute carrier family 35 member B3 2 2
MIRT653626 SLC30A3 solute carrier family 30 member 3 2 2
MIRT653669 SLC26A7 solute carrier family 26 member 7 2 2
MIRT653921 SERPINC1 serpin family C member 1 2 2
MIRT654247 RIMS4 regulating synaptic membrane exocytosis 4 2 2
MIRT654269 RGS17 regulator of G protein signaling 17 2 2
MIRT654347 RBM27 RNA binding motif protein 27 2 2
MIRT654547 RAB1A RAB1A, member RAS oncogene family 2 2
MIRT654617 PTPRM protein tyrosine phosphatase, receptor type M 2 2
MIRT654732 PRLR prolactin receptor 2 2
MIRT654749 PRKCB protein kinase C beta 2 2
MIRT654930 POLR3D RNA polymerase III subunit D 2 2
MIRT655446 PALM2-AKAP2 PALM2-AKAP2 readthrough 2 2
MIRT655562 P2RX7 purinergic receptor P2X 7 2 2
MIRT656527 MAGT1 magnesium transporter 1 2 2
MIRT656861 KIN Kin17 DNA and RNA binding protein 2 2
MIRT657149 ITGA1 integrin subunit alpha 1 2 2
MIRT657408 HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 2 2
MIRT657436 HHIP hedgehog interacting protein 2 2
MIRT657700 GPC5 glypican 5 2 2
MIRT657863 GJD2 gap junction protein delta 2 2 2
MIRT658049 FUT11 fucosyltransferase 11 2 2
MIRT658094 FOXO1 forkhead box O1 2 2
MIRT658147 STXBP2 syntaxin binding protein 2 2 2
MIRT658179 FBXO9 F-box protein 9 2 2
MIRT658492 EXOC7 exocyst complex component 7 2 2
MIRT658499 EXOC5 exocyst complex component 5 2 2
MIRT658680 EMP2 epithelial membrane protein 2 2 2
MIRT658814 EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 2 2
MIRT659024 DHTKD1 dehydrogenase E1 and transketolase domain containing 1 2 2
MIRT659164 DCTN5 dynactin subunit 5 2 4
MIRT659417 COL4A4 collagen type IV alpha 4 chain 2 2
MIRT659626 CDON cell adhesion associated, oncogene regulated 2 2
MIRT659716 CCDC93 coiled-coil domain containing 93 2 2
MIRT660019 C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 2 2
MIRT660043 C15orf61 chromosome 15 open reading frame 61 2 2
MIRT660349 BBX BBX, HMG-box containing 2 2
MIRT660791 AKAP2 A-kinase anchoring protein 2 2 2
MIRT660946 ACER3 alkaline ceramidase 3 2 2
MIRT661286 EPPIN epididymal peptidase inhibitor 2 2
MIRT661335 TBC1D15 TBC1 domain family member 15 2 2
MIRT661568 EPHX2 epoxide hydrolase 2 2 2
MIRT661635 UGT2B28 UDP glucuronosyltransferase family 2 member B28 2 2
MIRT661644 EPPIN-WFDC6 EPPIN-WFDC6 readthrough 2 2
MIRT661740 DTHD1 death domain containing 1 2 2
MIRT664290 C15orf40 chromosome 15 open reading frame 40 2 2
MIRT664578 CD44 CD44 molecule (Indian blood group) 2 2
MIRT664749 SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 2 2
MIRT665300 ZBTB38 zinc finger and BTB domain containing 38 2 2
MIRT666755 RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 2 2
MIRT668007 HCFC2 host cell factor C2 2 2
MIRT668745 DIO2 iodothyronine deiodinase 2 2 2
MIRT668871 CRY2 cryptochrome circadian clock 2 2 2
MIRT669122 CD84 CD84 molecule 2 2
MIRT669140 CD200 CD200 molecule 2 2
MIRT671844 PDE3A phosphodiesterase 3A 2 4
MIRT675259 LPP LIM domain containing preferred translocation partner in lipoma 2 2
MIRT685148 TACR3 tachykinin receptor 3 2 2
MIRT686088 PNPLA3 patatin like phospholipase domain containing 3 2 2
MIRT698994 SPAG9 sperm associated antigen 9 2 2
MIRT704256 DHCR24 24-dehydrocholesterol reductase 2 2
MIRT707224 STAM signal transducing adaptor molecule 2 2
MIRT708402 GRIN2A glutamate ionotropic receptor NMDA type subunit 2A 2 2
MIRT710458 METTL15 methyltransferase like 15 2 2
MIRT710869 B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 2 2
MIRT711130 CYYR1 cysteine and tyrosine rich 1 2 2
MIRT711188 PIGG phosphatidylinositol glycan anchor biosynthesis class G 2 2
MIRT711604 LHX5 LIM homeobox 5 2 2
MIRT712518 ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 2 2
MIRT713086 ZG16 zymogen granule protein 16 2 2
MIRT713245 SLC22A3 solute carrier family 22 member 3 2 2
MIRT714209 MRE11A MRE11 homolog, double strand break repair nuclease 2 2
MIRT714966 N4BP2 NEDD4 binding protein 2 2 2
MIRT715286 TXNL1 thioredoxin like 1 2 2
MIRT715440 RGS6 regulator of G protein signaling 6 2 2
MIRT715635 ZBTB8B zinc finger and BTB domain containing 8B 2 2
MIRT716055 C1orf210 chromosome 1 open reading frame 210 2 2
MIRT716895 BTN3A2 butyrophilin subfamily 3 member A2 2 2
MIRT716988 GPR155 G protein-coupled receptor 155 2 2
MIRT717086 EBF4 early B-cell factor 4 2 2
MIRT717172 UCHL3 ubiquitin C-terminal hydrolase L3 2 2
MIRT717666 THBS2 thrombospondin 2 2 2
MIRT717673 CDC42BPA CDC42 binding protein kinase alpha 2 2
MIRT717731 FGF1 fibroblast growth factor 1 2 2
MIRT718685 FZD2 frizzled class receptor 2 2 2
MIRT718907 GALR1 galanin receptor 1 2 2
MIRT719114 MAML1 mastermind like transcriptional coactivator 1 2 2
MIRT719699 STX6 syntaxin 6 2 2
MIRT719833 C22orf24 chromosome 22 open reading frame 24 2 2
MIRT719892 RRP36 ribosomal RNA processing 36 2 2
MIRT720159 POU2F2 POU class 2 homeobox 2 2 2
MIRT720310 CSRNP3 cysteine and serine rich nuclear protein 3 2 2
MIRT720718 RAPGEF6 Rap guanine nucleotide exchange factor 6 2 2
MIRT721982 RAD50 RAD50 double strand break repair protein 2 2
MIRT722357 BAG2 BCL2 associated athanogene 2 2 2
MIRT722552 FGFR1OP FGFR1 oncogene partner 2 2
MIRT723274 TAL2 TAL bHLH transcription factor 2 2 2
MIRT723795 MUC17 mucin 17, cell surface associated 2 2
MIRT723805 BDKRB2 bradykinin receptor B2 2 2
MIRT724133 MT1A metallothionein 1A 2 2
MIRT724520 LRP6 LDL receptor related protein 6 2 2
MIRT724538 ABCG5 ATP binding cassette subfamily G member 5 2 2
MIRT735269 Sirt4 sirtuin 4 4 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-130b N-ethyl-N-nitrosourea NULL 12967 Quantitative real-time PCR mouse liver 21029445 2010 up-regulated
miR-130b Diethylstilbestrol approved 448537 Microarray mammosphere-derived epithelial cells (MDEC) 19549897 2009 down-regulated
miR-130b Formaldehyde NULL 712 Microarray Human lung epithelial cells (A549) 21147603 2011 down-regulated
miR-130b Goserelin approved 47725 Microarray prostate 22674191 2012 down-regulated
miR-130b Ginsenoside Rh2 NULL 119307 Microarray NSCLC cell line A549 23152132 2013 up-regulated
miR-130b Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 down-regulated
miR-130b Comfrey NULL 6440495 Microarray rat liver 21370286 2011 up-regulated
miR-130b Chaihu Shugan San NULL NULL Microarray hippocampus 23947143 2013 down-regualted
miR-130b Perfluorooctane sulfonate NULL 74483 Microarray zebrafish embryos 20878907 2011 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-130b Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (SGC-7901)
hsa-mir-130b Imatinib 5291 NSC743414 approved sensitive High Chronic Myelogenous Leukemia tissue
hsa-mir-130b Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-mir-130b Cisplatin 5460033 NSC119875 approved resistant cell line (SGC-7901)
hsa-miR-130b-5p Doxorubicin 31703 NSC123127 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-130b-5p Verapamil 2520 NSC272366 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-130b-5p Paclitaxel 36314 NSC125973 approved resistant High Laryngeal Cancer cell line (Hep2)
hsa-miR-130b-5p Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (H358, H1993)
hsa-miR-130b-5p Paclitaxel 36314 NSC125973 approved sensitive High Non-Small Cell Lung Cancer cell line (H358, H1993)
hsa-miR-130b-5p Cisplatin 5460033 NSC119875 approved sensitive Low Cervical Cancer tissue
hsa-miR-130b-5p Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (AsPC-1)
hsa-miR-130b-5p Taxol 36314 NSC125973 approved resistant Low Nasopharyngeal Cancer cell line (5-8F, CNE-1)
hsa-miR-130b-5p Neferine 71531543 resistant Low Nasopharyngeal Cancer cell line (5-8F, CNE-1)
hsa-miR-130b-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-130b-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-miR-130b-5p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-130b-5p Tamoxifen 2733525 NSC180973 approved resistant cell line (TamR1)
hsa-miR-130b-5p Tamoxifen 2733525 NSC180973 approved resistant cell line (TamR4)
hsa-miR-130b-5p Cisplatin 5460033 NSC119875 approved resistant cell line (IGROV-1)
hsa-miR-130b-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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