miRTarBase - #MIRT038299


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pre-miRNA Information
pre-miRNA hsa-mir-130b   
Genomic Coordinates chr22: 21653304 - 21653385
Synonyms MIRN130B, mir-130b, MIR130B
Description Homo sapiens miR-130b stem-loop
Comment This sequence is the predicted human homologue of mouse miR-130b cloned from mouse embryonic stem cells .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-130b-5p
Sequence 13| ACUCUUUCCCUGUUGCACUAC |33
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 1 22 + 21653316 18684997, 29233923 MiREDiBase
A-to-I 20 22 + 21653335 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs774584516 1 dbSNP
rs1174814901 2 dbSNP
rs761813865 7 dbSNP
rs1414195475 8 dbSNP
rs1435758272 12 dbSNP
rs767568985 16 dbSNP
rs1371968909 20 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol MFSD6   
Synonyms MMR2, hMMR2
Description major facilitator superfamily domain containing 6
Transcript NM_017694   
Expression
Putative miRNA Targets on MFSD6
3'UTR of MFSD6
(miRNA target sites are highlighted)		 
>MFSD6|NM_017694|3'UTR
   1 GGGCATCCTGCTCATCTCACACCCTGCATGGAATCAGGCTCCTCAGCCAGGACACAGGGTGAGGCCCCCCAGCCAGGATA
  81 TGCCTCCCCTGGAGGAGCACAGCACTGCATATGCTTCTAAATATCTAAACTCATTAACATGGAAACACACACACAGGAGC
 161 TACAGTACATATTGGCAGGAAAAGGTAAACTTTCGTAATCTCATTGGAATTACAACAGGGAAATGGAGTTCAATGAGGAC
 241 TTTCAGTTCTTTGCTTGGTTAGGTTAAGGATGATAGAATTTCTCTGCCAGTGCAGTAAGAGTTGAAACCGGCAGTTACAC
 321 TAAGTAAGTGGAGGGAATGAAAGTGTTTCGAGGTGAATGTGGATATAATTTCCCTCTTCTGATTATTTATTCTTATTTGG
 401 TTCCTAACACAAACTGGGAAGAGATAGAATTCATCTATACTTTCTTTTTTCTTGGAGAGAACCGTTTAAAAAATTACAAG
 481 ATATATTTAAAAAGTAACCAGATAAAAGTAGCACATGTGCTTTTGTTAAAAATAAAGTTAAAAGTTAAAGTTAAAAAATG
 561 AAGTTAAAAGTTTCATCAGAAACTTTACATATCTTTAGCAAATATATTTTTATATGTGTATGGCATATAATGGAAATAAT
 641 TCTTTGAGCAACAGAAGCTATTATTAACTACTGCAAGCTAAGCCGAGCTTAAAAATGCCTTTTGTTTTAAATGGGCTTTG
 721 AGAAAAAAAACAGAAACAAGCGATTATTTCAAATCAACCAACCAACTCAGTATCCTGTGTTTTGATAGACAAGAGTTTAC
 801 TAAATATATTGATACTGTAAATAGCCTCTCTCGCTATTTACTATCTTATAGTAATTCAGGCTCTAATTAGCTGAGGGAAT
 881 GAAACACACAAAAATCACTGAATTCCTAAGAGTTCCTTAAATAAGCAGTACTAGTTACAAATCACAGTATAAGATTTAAG
 961 TGCCTGGGGGAAGGATACAATTTTTAGAAATTACATATTGGGTCAGTTTTGTTTTGTTTTTGGTGAGGAAAAGGTGGTAA
1041 ATAGGAAACCATGAATGGGAAGGATGGCAATAAGTAGCAACTATACTTTCCAATGACTAAAGAAAGAAAATCTCAGTATA
1121 TTCGTTCTCATGAAGACACAGTCAGACACTGGACAATGTAATGTATGCAACTGCAAACGTTACAACTGCAGCCAGAACAA
1201 TGGCTGGGTGGATCGCACGTAAAGCTTGCCACTAAAAATCAAAGCAGAGGTTAACAGGAAACCTGGGGGGAGTGTGGAAA
1281 AGGGAAAACTGTTTTAGCTGAATAAAGGTGAATTATATAATTTATAATAGCTGTGGATGAGCACAGGAGAGAGAGGAAAG
1361 AAAAGAACAGTCGAAATGAGCAACTCACCTTACCCTCTGACCCTGATTAGACAGGATCAATTGTAAAGTGAGGGCTTCTC
1441 CATGACACCATAGTTCTGCCCAATACTGCATTTGGGATAAGAAATTCTACACTTGGATGTCTCGCTTCACAATAAAACAC
1521 AGCTTAAAAATAAAATAACTGAAAGAAATAGAATTCAGCAAATAGTTATTTTTTGCACTTGAACTGAAACGTACTGTACT
1601 GTAAATTATGACTCATTTTAAGTGACCTTTAAAATCAGATGTATTTATTATGCTTGTGTAATTATAGAAATAAAGAAATG
1681 GGTGACAGGCTTAACCTCACCTATGAATGTACAGTATGTGGATTTGTGAAACTGACTGTAGGAAGTCAAAAACTTGTACT
1761 GTATCTTGTGTTTACAGTTCTGATTTATTCCTTTGAAAAGCCTGCTGTTTTGGAAATGCACAGTTGACATGTTGAAATAA
1841 AAATGAATACCATTTTTAAATGTTTCTTAAATGATAAAGATGTGACCAAACAAAAGTCCTATACTCTAATGAATGAGACC
1921 AAATTCAACATGCCTTTGTTATGGAACATTTACTGTGACAGCAGAATCGATAATGCAGTCATTTCCAGCCTTGTGAGCTG
2001 ACACCTTCATGGGTTTGTGGACTTTGTGACTTTTTCTTCCTGTCCCCAAAGTGCCATATGCTACCTTAAAAAATATTAAA
2081 GTGAATTCAAATTACAT
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cauCACGUUGUCC-CUUUCUCa 5'
             | || ||||| ||:|||| 
Target 5' gatGAGC-ACAGGAGAGAGAGg 3'
 1336 - 1356 145.00 -17.80
2 
miRNA  3' caUCACGUUGUCCCUUU--CUCa 5'
            | | |||||||||||  ||| 
Target 5' gaATTACAACAGGGAAATGGAGt 3'
 207 - 229 139.00 -20.00
3 
miRNA  3' caucacGUUGUCCCUUUCUCa 5'
                |||   ||:||||| 
Target 5' ctaacaCAAACTGGGAAGAGa 3'
 404 - 424 135.00 -12.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30148099 45 COSMIC
COSN31593131 71 COSMIC
COSN30532272 128 COSMIC
COSN17076513 275 COSMIC
COSN6160318 1325 COSMIC
COSN31556210 1613 COSMIC
COSN28767098 1636 COSMIC
COSN1813999 1638 COSMIC
COSN31490816 1666 COSMIC
COSN31533183 1814 COSMIC
COSN7153343 1956 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs138926881 3 dbSNP
rs371140826 6 dbSNP
rs746963765 9 dbSNP
rs770934125 12 dbSNP
rs781165134 17 dbSNP
rs1310879421 23 dbSNP
rs199987141 24 dbSNP
rs1346530134 25 dbSNP
rs769888840 29 dbSNP
rs775845991 36 dbSNP
rs1314680905 42 dbSNP
rs1464024731 44 dbSNP
rs544205749 48 dbSNP
rs1256275882 49 dbSNP
rs1288112253 54 dbSNP
rs867145251 61 dbSNP
rs1028052005 65 dbSNP
rs953700452 66 dbSNP
rs1300282117 67 dbSNP
rs1420531092 71 dbSNP
rs562510153 78 dbSNP
rs1435461206 83 dbSNP
rs531229116 85 dbSNP
rs761264098 86 dbSNP
rs546550151 88 dbSNP
rs1487522138 98 dbSNP
rs1019860851 99 dbSNP
rs61742316 100 dbSNP
rs980227684 108 dbSNP
rs978376296 112 dbSNP
rs374143867 116 dbSNP
rs1211578766 120 dbSNP
rs957261623 125 dbSNP
rs936842014 133 dbSNP
rs1228140193 141 dbSNP
rs1294788736 141 dbSNP
rs528703396 142 dbSNP
rs988723905 147 dbSNP
rs1278591099 148 dbSNP
rs1400890341 149 dbSNP
rs1375037351 151 dbSNP
rs1301271904 155 dbSNP
rs1467671251 169 dbSNP
rs1305434379 170 dbSNP
rs1206225727 171 dbSNP
rs879871382 173 dbSNP
rs61743479 180 dbSNP
rs1311058919 181 dbSNP
rs987193726 187 dbSNP
rs1467685875 189 dbSNP
rs986614948 195 dbSNP
rs568547675 196 dbSNP
rs1254816698 202 dbSNP
rs188158647 205 dbSNP
rs1224971679 229 dbSNP
rs1201759219 234 dbSNP
rs1483293139 242 dbSNP
rs949407630 250 dbSNP
rs1196733121 255 dbSNP
rs529406315 258 dbSNP
rs1258508474 275 dbSNP
rs907876502 285 dbSNP
rs1167141905 286 dbSNP
rs536900740 287 dbSNP
rs768444137 290 dbSNP
rs898313045 300 dbSNP
rs1330749237 309 dbSNP
rs550556798 311 dbSNP
rs1403046394 314 dbSNP
rs1038858458 317 dbSNP
rs1461260989 317 dbSNP
rs889571064 320 dbSNP
rs1459947797 321 dbSNP
rs1007981654 330 dbSNP
rs1328449216 341 dbSNP
rs1249262929 349 dbSNP
rs898529963 350 dbSNP
rs115461928 351 dbSNP
rs1238732521 358 dbSNP
rs1212932900 366 dbSNP
rs1354003524 367 dbSNP
rs1047366850 376 dbSNP
rs1247336473 382 dbSNP
rs1322533994 383 dbSNP
rs1430406436 391 dbSNP
rs896756879 408 dbSNP
rs1013817974 413 dbSNP
rs1000163178 418 dbSNP
rs1332635585 419 dbSNP
rs550747909 426 dbSNP
rs7419755 432 dbSNP
rs1165340537 440 dbSNP
rs958181895 450 dbSNP
rs1273352860 454 dbSNP
rs991022213 460 dbSNP
rs539331286 464 dbSNP
rs145748674 465 dbSNP
rs905321328 469 dbSNP
rs1001332827 480 dbSNP
rs1193008107 482 dbSNP
rs1033168093 491 dbSNP
rs957089772 514 dbSNP
rs1210182337 516 dbSNP
rs148940730 519 dbSNP
rs1238160477 533 dbSNP
rs1468835926 533 dbSNP
rs1356027722 536 dbSNP
rs907841761 541 dbSNP
rs1019885560 548 dbSNP
rs1240130433 550 dbSNP
rs955299239 564 dbSNP
rs192868873 575 dbSNP
rs1326059458 580 dbSNP
rs986639461 581 dbSNP
rs1036895766 583 dbSNP
rs369066043 584 dbSNP
rs1295972014 586 dbSNP
rs764843558 590 dbSNP
rs1421137817 594 dbSNP
rs974212299 613 dbSNP
rs919984299 622 dbSNP
rs1049510199 638 dbSNP
rs889636665 640 dbSNP
rs1379333685 646 dbSNP
rs1199426116 655 dbSNP
rs1008364961 666 dbSNP
rs930019461 670 dbSNP
rs1417434215 685 dbSNP
rs370343639 686 dbSNP
rs1047105492 716 dbSNP
rs373028020 717 dbSNP
rs1286879787 723 dbSNP
rs949620637 724 dbSNP
rs1342895804 728 dbSNP
rs1277127933 731 dbSNP
rs1234526604 732 dbSNP
rs1045725381 738 dbSNP
rs555129484 742 dbSNP
rs1400609480 743 dbSNP
rs905395743 745 dbSNP
rs1333051993 748 dbSNP
rs1412283061 751 dbSNP
rs1316912895 758 dbSNP
rs1403649288 780 dbSNP
rs777336922 782 dbSNP
rs1054234852 787 dbSNP
rs1421271453 787 dbSNP
rs1195534062 791 dbSNP
rs1431936984 794 dbSNP
rs1278369093 802 dbSNP
rs958316906 810 dbSNP
rs760067813 828 dbSNP
rs1440772432 829 dbSNP
rs573672056 831 dbSNP
rs1201593542 833 dbSNP
rs184487238 834 dbSNP
rs1256606688 841 dbSNP
rs556175847 844 dbSNP
rs763181821 850 dbSNP
rs1341804226 864 dbSNP
rs1334222079 869 dbSNP
rs1465074685 884 dbSNP
rs1398063249 896 dbSNP
rs1172668203 899 dbSNP
rs556798935 901 dbSNP
rs114502914 907 dbSNP
rs145631753 910 dbSNP
rs963932557 911 dbSNP
rs1471927977 913 dbSNP
rs189507503 921 dbSNP
rs931196390 929 dbSNP
rs919739276 937 dbSNP
rs1474329774 939 dbSNP
rs200931500 950 dbSNP
rs1201010140 954 dbSNP
rs982826715 963 dbSNP
rs943909925 980 dbSNP
rs917964694 991 dbSNP
rs1284381424 996 dbSNP
rs1445427114 1009 dbSNP
rs1041181442 1012 dbSNP
rs1469751146 1029 dbSNP
rs757944760 1030 dbSNP
rs540810488 1034 dbSNP
rs73979258 1038 dbSNP
rs1053412602 1039 dbSNP
rs529366066 1043 dbSNP
rs1162410655 1045 dbSNP
rs550694772 1049 dbSNP
rs1312623168 1052 dbSNP
rs1045349008 1057 dbSNP
rs1164399895 1057 dbSNP
rs1012479239 1059 dbSNP
rs926849822 1064 dbSNP
rs1412526100 1071 dbSNP
rs562507873 1075 dbSNP
rs936916139 1084 dbSNP
rs1481233075 1085 dbSNP
rs373798575 1089 dbSNP
rs1246531437 1090 dbSNP
rs1054377370 1092 dbSNP
rs1453633669 1094 dbSNP
rs751772518 1097 dbSNP
rs779624528 1099 dbSNP
rs1238887894 1104 dbSNP
rs1350949822 1107 dbSNP
rs1340482403 1124 dbSNP
rs1310792030 1125 dbSNP
rs1240853444 1128 dbSNP
rs1366784987 1131 dbSNP
rs1291675618 1133 dbSNP
rs1237727772 1136 dbSNP
rs1277652140 1137 dbSNP
rs1438375352 1139 dbSNP
rs1350194776 1147 dbSNP
rs1303986117 1149 dbSNP
rs1352784601 1163 dbSNP
rs533176041 1167 dbSNP
rs1279309928 1177 dbSNP
rs1484599010 1179 dbSNP
rs750979593 1180 dbSNP
rs1015420571 1183 dbSNP
rs138175515 1184 dbSNP
rs1179774620 1186 dbSNP
rs973465937 1200 dbSNP
rs1287594606 1201 dbSNP
rs890820310 1207 dbSNP
rs1294243404 1210 dbSNP
rs1027584320 1213 dbSNP
rs953398423 1215 dbSNP
rs1008287832 1216 dbSNP
rs367642212 1219 dbSNP
rs976654462 1220 dbSNP
rs750365736 1222 dbSNP
rs1174651880 1247 dbSNP
rs1416639473 1248 dbSNP
rs1430485975 1250 dbSNP
rs1193358955 1257 dbSNP
rs34750665 1257 dbSNP
rs1477024705 1261 dbSNP
rs143086708 1268 dbSNP
rs1393653507 1273 dbSNP
rs1026824036 1276 dbSNP
rs549137628 1290 dbSNP
rs1253738346 1292 dbSNP
rs982901732 1303 dbSNP
rs1025052355 1304 dbSNP
rs1212227300 1306 dbSNP
rs1175070216 1309 dbSNP
rs1402502858 1316 dbSNP
rs935036163 1328 dbSNP
rs1257300524 1332 dbSNP
rs970741286 1333 dbSNP
rs1326241221 1341 dbSNP
rs567394722 1349 dbSNP
rs926617006 1352 dbSNP
rs561086361 1367 dbSNP
rs1378606946 1369 dbSNP
rs145145666 1370 dbSNP
rs779805669 1373 dbSNP
rs1407514116 1374 dbSNP
rs1464407758 1389 dbSNP
rs914104527 1391 dbSNP
rs556300275 1393 dbSNP
rs906824028 1395 dbSNP
rs1004205854 1401 dbSNP
rs945534994 1402 dbSNP
rs1253527739 1408 dbSNP
rs1183126102 1409 dbSNP
rs1041471137 1416 dbSNP
rs573241830 1418 dbSNP
rs1256758181 1419 dbSNP
rs943770987 1421 dbSNP
rs1196606075 1429 dbSNP
rs994859030 1430 dbSNP
rs1194343757 1439 dbSNP
rs1027719556 1443 dbSNP
rs1228489774 1460 dbSNP
rs1039784227 1463 dbSNP
rs1321313143 1468 dbSNP
rs953367108 1470 dbSNP
rs986130738 1473 dbSNP
rs899460848 1495 dbSNP
rs1183194226 1501 dbSNP
rs995870437 1504 dbSNP
rs754753741 1505 dbSNP
rs1399158544 1507 dbSNP
rs1455821916 1517 dbSNP
rs1457683062 1522 dbSNP
rs1194690373 1540 dbSNP
rs1372905443 1550 dbSNP
rs749694006 1555 dbSNP
rs1026898462 1556 dbSNP
rs1461151055 1557 dbSNP
rs191159246 1561 dbSNP
rs778776629 1564 dbSNP
rs956547635 1569 dbSNP
rs1459014828 1577 dbSNP
rs989213557 1586 dbSNP
rs1209057241 1591 dbSNP
rs1465693294 1591 dbSNP
rs1325073460 1597 dbSNP
rs553524801 1602 dbSNP
rs34069143 1616 dbSNP
rs1360344923 1619 dbSNP
rs1004031195 1623 dbSNP
rs1024790650 1627 dbSNP
rs947698732 1628 dbSNP
rs7721 1636 dbSNP
rs1308274512 1644 dbSNP
rs1386576438 1666 dbSNP
rs980845932 1671 dbSNP
rs148360239 1680 dbSNP
rs1253300830 1690 dbSNP
rs1443448020 1700 dbSNP
rs1424884330 1706 dbSNP
rs1359395763 1709 dbSNP
rs866567601 1714 dbSNP
rs1440955406 1722 dbSNP
rs565159192 1731 dbSNP
rs1213173725 1741 dbSNP
rs1271782842 1743 dbSNP
rs1269201624 1756 dbSNP
rs1382689303 1756 dbSNP
rs1470199302 1758 dbSNP
rs989718823 1760 dbSNP
rs1285453167 1761 dbSNP
rs1128723 1764 dbSNP
rs1352854422 1767 dbSNP
rs945606655 1769 dbSNP
rs574162989 1771 dbSNP
rs1233155215 1779 dbSNP
rs1329766701 1780 dbSNP
rs1285555085 1782 dbSNP
rs897980892 1786 dbSNP
rs1339476324 1791 dbSNP
rs1295912394 1796 dbSNP
rs1401954271 1802 dbSNP
rs375934842 1802 dbSNP
rs1427174374 1803 dbSNP
rs1171999115 1808 dbSNP
rs1464472652 1814 dbSNP
rs1431226816 1823 dbSNP
rs987610289 1825 dbSNP
rs1049127955 1833 dbSNP
rs1191691327 1839 dbSNP
rs1425341622 1843 dbSNP
rs1477834007 1851 dbSNP
rs1285029180 1852 dbSNP
rs1200432845 1853 dbSNP
rs1343448804 1855 dbSNP
rs912025051 1861 dbSNP
rs1224531400 1868 dbSNP
rs943786853 1874 dbSNP
rs1391698844 1875 dbSNP
rs1462938513 1885 dbSNP
rs1039453648 1888 dbSNP
rs116319890 1893 dbSNP
rs562664275 1894 dbSNP
rs930983789 1919 dbSNP
rs551298031 1920 dbSNP
rs1297940881 1932 dbSNP
rs966456044 1933 dbSNP
rs1394261736 1940 dbSNP
rs1408253448 1942 dbSNP
rs1176996200 1944 dbSNP
rs775697044 1945 dbSNP
rs1232944725 1946 dbSNP
rs1291490708 1954 dbSNP
rs1421201141 1960 dbSNP
rs1166430975 1969 dbSNP
rs887042844 1979 dbSNP
rs1242814020 1985 dbSNP
rs1337115664 1987 dbSNP
rs538672689 1987 dbSNP
rs1186967689 1988 dbSNP
rs1222938420 1992 dbSNP
rs563171228 1996 dbSNP
rs1245529369 2000 dbSNP
rs1485063913 2003 dbSNP
rs956515440 2013 dbSNP
rs1024822116 2018 dbSNP
rs1256551184 2022 dbSNP
rs57946998 2027 dbSNP
rs143693476 2031 dbSNP
rs546802386 2031 dbSNP
rs980941303 2041 dbSNP
rs927627559 2044 dbSNP
rs1488394614 2046 dbSNP
rs1445936823 2049 dbSNP
rs939039439 2050 dbSNP
rs1033755625 2052 dbSNP
rs549047344 2057 dbSNP
rs1410279878 2066 dbSNP
rs1420517864 2073 dbSNP
rs1010880252 2077 dbSNP
rs1415016556 2079 dbSNP
rs1162827081 2096 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Flp-In T-REx 293-hAGO1 cells
Location of target site CDS
Original Description (Extracted from the article) ... Validation of interactions identified by CLASH suppports their reliability. ...

- Helwak A; Kudla G; Dudnakova T; Tollervey D, 2013, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cauCACGUUGUC-CCUUUCUCa 5'
             |||| |||| |||:|| | 
Target 5' ---GTGC-ACAGAGGAGAGTGa 3'
 		1 - 18
2 
miRNA  3' caUC-ACGUUGUCCCUUUCUca 5'
            || || : |: ||:|:||  
Target 5' tcAGCTG-GCCGCGGGAGGA-- 3'
 		31 - 49
Article - Helwak A; Kudla G; Dudnakova T; Tollervey D
- Cell, 2013
MicroRNAs (miRNAs) play key roles in gene regulation, but reliable bioinformatic or experimental identification of their targets remains difficult. To provide an unbiased view of human miRNA targets, we developed a technique for ligation and sequencing of miRNA-target RNA duplexes associated with human AGO1. Here, we report data sets of more than 18,000 high-confidence miRNA-mRNA interactions. The binding of most miRNAs includes the 5' seed region, but around 60% of seed interactions are noncanonical, containing bulged or mismatched nucleotides. Moreover, seed interactions are generally accompanied by specific, nonseed base pairing. 18% of miRNA-mRNA interactions involve the miRNA 3' end, with little evidence for 5' contacts, and some of these were functionally validated. Analyses of miRNA:mRNA base pairing showed that miRNA species systematically differ in their target RNA interactions, and strongly overrepresented motifs were found in the interaction sites of several miRNAs. We speculate that these affect the response of RISC to miRNA-target binding.
LinkOut: [PMID: 23622248]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE42095 Differentiated embryonic stem cells -0.629 6.5e-4 -0.480 1.0e-2 23 Click to see details
GSE38226 Liver fibrosis -0.521 7.7e-3 -0.483 1.3e-2 21 Click to see details
GSE21687 Ependynoma primary tumors -0.273 1.5e-2 -0.255 2.1e-2 64 Click to see details
GSE28260 Renal cortex and medulla 0.563 2.3e-2 0.571 2.1e-2 13 Click to see details
GSE19783 ER+ ER+ breast cancer 0.383 4.8e-2 0.373 5.3e-2 20 Click to see details
GSE32688 Pancreatic cancer 0.263 7.3e-2 0.336 3.0e-2 32 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.259 1.1e-1 0.275 9.2e-2 25 Click to see details
GSE19783 ER- ER- breast cancer -0.138 1.1e-1 -0.032 3.9e-1 79 Click to see details
GSE19350 CNS germ cell tumors -0.357 1.3e-1 0.021 4.7e-1 12 Click to see details
GSE15076 Monocyte-derived dendritic cells -0.48 1.4e-1 -0.750 2.6e-2 7 Click to see details
GSE19536 Breast cancer -0.08 2.1e-1 0.003 4.9e-1 100 Click to see details
GSE26953 Aortic valvular endothelial cells -0.154 2.4e-1 -0.207 1.7e-1 24 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.162 2.5e-1 0.561 5.0e-3 20 Click to see details
GSE35602 Colorectal cancer stromal tissue -0.087 3.4e-1 0.405 2.2e-2 25 Click to see details
GSE28544 Breast cancer 0.045 4.2e-1 0.427 1.9e-2 24 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
KICH -0.636 0 -0.083 0.35 25 Click to see details
LIHC -0.465 0 -0.392 0 49 Click to see details
KIRC -0.271 0.01 -0.239 0.02 68 Click to see details
STAD 0.369 0.02 0.313 0.04 31 Click to see details
THCA -0.229 0.04 -0.194 0.07 59 Click to see details
LUSC 0.252 0.06 0.229 0.08 38 Click to see details
ESCA -0.45 0.08 -0.564 0.04 11 Click to see details
HNSC 0.208 0.09 0.165 0.15 42 Click to see details
PCPG -0.928 0.12 -0.500 0.33 3 Click to see details
KIRP -0.21 0.12 -0.177 0.17 32 Click to see details
UCEC -0.274 0.13 0.025 0.46 19 Click to see details
CESC 0.919 0.13 0.500 0.33 3 Click to see details
BLCA -0.258 0.16 -0.108 0.34 17 Click to see details
CHOL 0.285 0.23 0.317 0.2 9 Click to see details
LUAD -0.194 0.27 -0.434 0.08 12 Click to see details
BRCA -0.036 0.37 0.020 0.43 84 Click to see details
PRAD 0.047 0.37 -0.007 0.48 50 Click to see details
COAD -0.101 0.41 -0.262 0.27 8 Click to see details
PAAD -0.023 0.49 0.600 0.2 4 Click to see details
PAAD -0.023 0.49 0.600 0.2 4 Click to see details
PAAD -0.023 0.49 0.600 0.2 4 Click to see details
337 hsa-miR-130b-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT038280 ASF1B anti-silencing function 1B histone chaperone 1 1
MIRT038281 MACC1 MACC1, MET transcriptional regulator 1 1
MIRT038282 ADPRHL2 ADP-ribosylhydrolase like 2 1 1
MIRT038283 MYBPC1 myosin binding protein C, slow type 1 1
MIRT038284 NCOR2 nuclear receptor corepressor 2 1 1
MIRT038285 DPYSL5 dihydropyrimidinase like 5 1 1
MIRT038286 EMC1 ER membrane protein complex subunit 1 1 1
MIRT038287 DDX3X DEAD-box helicase 3, X-linked 1 1
MIRT038288 CDC5L cell division cycle 5 like 1 1
MIRT038289 OGDHL oxoglutarate dehydrogenase like 1 1
MIRT038290 SRCAP Snf2 related CREBBP activator protein 1 1
MIRT038291 POLD3 DNA polymerase delta 3, accessory subunit 1 1
MIRT038292 PDS5A PDS5 cohesin associated factor A 1 1
MIRT038293 COX6B1 cytochrome c oxidase subunit 6B1 1 1
MIRT038294 COPB1 coatomer protein complex subunit beta 1 1 1
MIRT038295 BRAT1 BRCA1 associated ATM activator 1 1 1
MIRT038296 NOTCH2 notch 2 2 3
MIRT038297 RPL8 ribosomal protein L8 1 1
MIRT038298 HBS1L HBS1 like translational GTPase 1 1
MIRT038299 MFSD6 major facilitator superfamily domain containing 6 1 1
MIRT038300 SSH2 slingshot protein phosphatase 2 1 1
MIRT038301 PTPN11 protein tyrosine phosphatase, non-receptor type 11 1 1
MIRT038302 PAGR1 PAXIP1 associated glutamate rich protein 1 2 3
MIRT038303 ALDH1B1 aldehyde dehydrogenase 1 family member B1 1 1
MIRT038304 TTC3 tetratricopeptide repeat domain 3 1 1
MIRT038305 EP300 E1A binding protein p300 1 1
MIRT038306 PCDHGB4 protocadherin gamma subfamily B, 4 1 1
MIRT038307 CDC37L1 cell division cycle 37 like 1 1 1
MIRT038308 HELZ helicase with zinc finger 1 1
MIRT038309 JMY junction mediating and regulatory protein, p53 cofactor 1 1
MIRT038310 MEIS3 Meis homeobox 3 1 1
MIRT038311 SMG5 SMG5, nonsense mediated mRNA decay factor 1 1
MIRT038312 FAM72A family with sequence similarity 72 member A 1 1
MIRT038313 CGNL1 cingulin like 1 1 1
MIRT038314 HNRNPR heterogeneous nuclear ribonucleoprotein R 1 1
MIRT038315 WEE1 WEE1 G2 checkpoint kinase 1 1
MIRT038316 HSPA8 heat shock protein family A (Hsp70) member 8 1 1
MIRT038317 CHD1 chromodomain helicase DNA binding protein 1 1 1
MIRT038318 FASN fatty acid synthase 1 1
MIRT038319 PDHA1 pyruvate dehydrogenase E1 alpha 1 subunit 1 1
MIRT038320 DZIP3 DAZ interacting zinc finger protein 3 1 1
MIRT038321 CSE1L chromosome segregation 1 like 1 1
MIRT038322 VCL vinculin 1 1
MIRT038323 RNF10 ring finger protein 10 1 1
MIRT038324 AAMP angio associated migratory cell protein 1 1
MIRT038325 SMIM12 small integral membrane protein 12 1 1
MIRT038326 IKZF2 IKAROS family zinc finger 2 1 1
MIRT038327 RPL36AL ribosomal protein L36a like 1 1
MIRT038328 MID1 midline 1 1 1
MIRT038329 MTPN myotrophin 1 1
MIRT038330 ND6 NADH dehydrogenase, subunit 6 (complex I) 1 1
MIRT038331 HSPA1B heat shock protein family A (Hsp70) member 1B 1 1
MIRT038332 PSD3 pleckstrin and Sec7 domain containing 3 1 1
MIRT038333 TMEM167A transmembrane protein 167A 1 1
MIRT038334 SECISBP2 SECIS binding protein 2 1 1
MIRT038335 PTMA prothymosin, alpha 1 1
MIRT038336 PPP1R12C protein phosphatase 1 regulatory subunit 12C 1 1
MIRT097680 ARRDC3 arrestin domain containing 3 2 2
MIRT120585 ANKRD28 ankyrin repeat domain 28 2 2
MIRT134442 KDM5A lysine demethylase 5A 2 2
MIRT162005 TFRC transferrin receptor 2 2
MIRT211714 OTUD4 OTU deubiquitinase 4 2 4
MIRT287594 KANSL1 KAT8 regulatory NSL complex subunit 1 2 2
MIRT333938 TMCO1 transmembrane and coiled-coil domains 1 2 4
MIRT339811 ZIC5 Zic family member 5 2 2
MIRT370983 SCOC short coiled-coil protein 2 2
MIRT404962 COA4 cytochrome c oxidase assembly factor 4 homolog 2 2
MIRT442925 TFDP2 transcription factor Dp-2 2 2
MIRT444887 TMEM196 transmembrane protein 196 2 2
MIRT447218 ATXN7 ataxin 7 2 2
MIRT450592 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 2 2
MIRT450608 HLA-DOA major histocompatibility complex, class II, DO alpha 2 2
MIRT462474 FIZ1 FLT3 interacting zinc finger 1 2 2
MIRT471095 PIK3C2B phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta 2 2
MIRT471562 PATL1 PAT1 homolog 1, processing body mRNA decay factor 2 6
MIRT482059 ALG9 ALG9, alpha-1,2-mannosyltransferase 2 2
MIRT486040 UBBP4 ubiquitin B pseudogene 4 2 2
MIRT500478 ZC3H11A zinc finger CCCH-type containing 11A 2 2
MIRT500538 XPO4 exportin 4 2 2
MIRT505896 RIMS3 regulating synaptic membrane exocytosis 3 2 6
MIRT512067 DEK DEK proto-oncogene 2 6
MIRT512542 ZNF793 zinc finger protein 793 2 4
MIRT524872 ARID3A AT-rich interaction domain 3A 2 4
MIRT529391 NSFL1C NSFL1 cofactor 2 2
MIRT530542 SYNPO synaptopodin 2 2
MIRT533816 TIMM17A translocase of inner mitochondrial membrane 17A 2 6
MIRT536729 IGF1 insulin like growth factor 1 2 2
MIRT549717 NUP37 nucleoporin 37 2 2
MIRT550783 VAV3 vav guanine nucleotide exchange factor 3 2 2
MIRT551510 PLP1 proteolipid protein 1 2 2
MIRT553360 TRIM8 tripartite motif containing 8 2 2
MIRT555321 PPP2CB protein phosphatase 2 catalytic subunit beta 2 2
MIRT556293 MAP3K5 mitogen-activated protein kinase kinase kinase 5 2 2
MIRT556816 KIAA1161 myogenesis regulating glycosidase (putative) 2 4
MIRT558194 EIF2S1 eukaryotic translation initiation factor 2 subunit alpha 2 4
MIRT572484 PRR14L proline rich 14 like 2 2
MIRT607361 TNS1 tensin 1 2 6
MIRT609536 ADPRH ADP-ribosylarginine hydrolase 2 2
MIRT609689 EMX2 empty spiracles homeobox 2 2 2
MIRT609769 PLCL1 phospholipase C like 1 (inactive) 2 2
MIRT609846 ZNF557 zinc finger protein 557 2 2
MIRT611396 ATP9A ATPase phospholipid transporting 9A (putative) 2 2
MIRT611989 WDR59 WD repeat domain 59 2 2
MIRT612747 MYOCD myocardin 2 2
MIRT613417 GOSR2 golgi SNAP receptor complex member 2 2 4
MIRT613455 ZFX zinc finger protein, X-linked 2 2
MIRT613568 YY2 YY2 transcription factor 2 2
MIRT613694 QPRT quinolinate phosphoribosyltransferase 2 2
MIRT613740 GK5 glycerol kinase 5 (putative) 2 4
MIRT614178 FAM53B family with sequence similarity 53 member B 2 2
MIRT614195 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 2 2
MIRT614852 PLEKHA6 pleckstrin homology domain containing A6 2 2
MIRT615318 MLXIPL MLX interacting protein like 2 2
MIRT615683 NAV2 neuron navigator 2 2 2
MIRT615745 PRIM1 DNA primase subunit 1 2 2
MIRT615864 HSPA6 heat shock protein family A (Hsp70) member 6 2 2
MIRT615972 ASCL1 achaete-scute family bHLH transcription factor 1 2 2
MIRT617213 CERS4 ceramide synthase 4 2 2
MIRT617654 RWDD1 RWD domain containing 1 2 2
MIRT617762 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT618224 CST3 cystatin C 2 2
MIRT618405 AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 2 2
MIRT618610 SHOX short stature homeobox 2 2
MIRT618662 ATP6AP1L ATPase H+ transporting accessory protein 1 like 2 2
MIRT619266 QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 2 2
MIRT619363 CFHR5 complement factor H related 5 2 2
MIRT619924 NLRP9 NLR family pyrin domain containing 9 2 2
MIRT620138 ZNF283 zinc finger protein 283 2 2
MIRT620176 EGFLAM EGF like, fibronectin type III and laminin G domains 2 2
MIRT620366 CD55 CD55 molecule (Cromer blood group) 2 2
MIRT620637 RFT1 RFT1 homolog 2 2
MIRT620735 CCL16 C-C motif chemokine ligand 16 2 2
MIRT620846 ATG10 autophagy related 10 2 2
MIRT620904 MUT methylmalonyl-CoA mutase 2 2
MIRT621212 SULT1C4 sulfotransferase family 1C member 4 2 2
MIRT621842 TGFBR3 transforming growth factor beta receptor 3 2 2
MIRT622034 STAT5A signal transducer and activator of transcription 5A 2 2
MIRT622118 SPRY3 sprouty RTK signaling antagonist 3 2 2
MIRT622291 SH3PXD2A SH3 and PX domains 2A 2 2
MIRT622592 PRRG4 proline rich and Gla domain 4 2 4
MIRT622604 PROM1 prominin 1 2 2
MIRT622690 PLSCR1 phospholipid scramblase 1 2 2
MIRT622774 PGM2L1 phosphoglucomutase 2 like 1 2 2
MIRT622853 PDGFA platelet derived growth factor subunit A 2 2
MIRT623017 ONECUT3 one cut homeobox 3 2 2
MIRT623102 NLGN4X neuroligin 4, X-linked 2 2
MIRT623420 KMT2A lysine methyltransferase 2A 2 2
MIRT623423 KLHL28 kelch like family member 28 2 2
MIRT623535 KCNJ6 potassium voltage-gated channel subfamily J member 6 2 2
MIRT623958 FBXL16 F-box and leucine rich repeat protein 16 2 2
MIRT624042 ELAVL3 ELAV like RNA binding protein 3 2 2
MIRT624117 DNAH10OS dynein axonemal heavy chain 10 opposite strand 2 2
MIRT624147 DIAPH1 diaphanous related formin 1 2 2
MIRT624368 CDK12 cyclin dependent kinase 12 2 2
MIRT624408 CCDC171 coiled-coil domain containing 171 2 2
MIRT624459 CALCOCO2 calcium binding and coiled-coil domain 2 2 2
MIRT624854 ABI2 abl interactor 2 2 2
MIRT625452 RANGAP1 Ran GTPase activating protein 1 2 2
MIRT625938 SCYL3 SCY1 like pseudokinase 3 2 2
MIRT625949 OLIG3 oligodendrocyte transcription factor 3 2 2
MIRT626291 ZNF85 zinc finger protein 85 2 2
MIRT626907 NRN1 neuritin 1 2 2
MIRT627003 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT627031 TMEM109 transmembrane protein 109 2 2
MIRT628152 HIP1 huntingtin interacting protein 1 2 2
MIRT628990 PITPNM3 PITPNM family member 3 2 2
MIRT630432 LHX9 LIM homeobox 9 2 2
MIRT631541 AS3MT arsenite methyltransferase 2 2
MIRT635194 NFKBID NFKB inhibitor delta 2 2
MIRT635814 KCNK6 potassium two pore domain channel subfamily K member 6 2 2
MIRT636226 SLC5A12 solute carrier family 5 member 12 2 2
MIRT636304 PSMB5 proteasome subunit beta 5 2 2
MIRT636504 GDAP1L1 ganglioside induced differentiation associated protein 1 like 1 2 2
MIRT636830 FSIP2 fibrous sheath interacting protein 2 2 2
MIRT636857 ZSCAN2 zinc finger and SCAN domain containing 2 2 2
MIRT637017 TRABD2A TraB domain containing 2A 2 2
MIRT638338 RCAN1 regulator of calcineurin 1 2 2
MIRT638911 CBLN2 cerebellin 2 precursor 2 2
MIRT639353 TBXA2R thromboxane A2 receptor 2 2
MIRT639416 FAM26E calcium homeostasis modulator family member 5 2 4
MIRT639532 CD86 CD86 molecule 2 2
MIRT639805 AHCY adenosylhomocysteinase 2 2
MIRT640375 UQCRB ubiquinol-cytochrome c reductase binding protein 2 2
MIRT640605 PPARA peroxisome proliferator activated receptor alpha 2 2
MIRT641761 SF3A1 splicing factor 3a subunit 1 2 2
MIRT641794 USP32 ubiquitin specific peptidase 32 2 2
MIRT641879 SREK1 splicing regulatory glutamic acid and lysine rich protein 1 2 2
MIRT641987 OXSR1 oxidative stress responsive 1 2 2
MIRT642352 C19orf40 Fanconi anemia core complex associated protein 24 1 1
MIRT642469 RSL1D1 ribosomal L1 domain containing 1 2 2
MIRT642724 ATXN3 ataxin 3 2 2
MIRT642758 SDHAF2 succinate dehydrogenase complex assembly factor 2 2 2
MIRT642771 FAM9C family with sequence similarity 9 member C 2 2
MIRT643191 HYPK huntingtin interacting protein K 2 2
MIRT643244 PRSS21 protease, serine 21 2 2
MIRT643901 TCEB2 elongin B 2 2
MIRT643957 GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 2 2
MIRT644161 GIN1 gypsy retrotransposon integrase 1 2 2
MIRT644297 HRH1 histamine receptor H1 2 2
MIRT644374 ZNF286A zinc finger protein 286A 2 2
MIRT644407 FRMD6 FERM domain containing 6 2 2
MIRT644942 ATXN3L ataxin 3 like 2 2
MIRT645143 CUBN cubilin 2 2
MIRT645327 C9orf64 chromosome 9 open reading frame 64 2 2
MIRT645335 DHRS3 dehydrogenase/reductase 3 2 2
MIRT645469 SPIN3 spindlin family member 3 2 2
MIRT645496 TRIM63 tripartite motif containing 63 2 2
MIRT645921 PLXNA3 plexin A3 2 2
MIRT645955 TTF2 transcription termination factor 2 2 2
MIRT646031 S100A7A S100 calcium binding protein A7A 2 2
MIRT646208 DUSP10 dual specificity phosphatase 10 2 2
MIRT647166 TMLHE trimethyllysine hydroxylase, epsilon 2 2
MIRT647288 JAG2 jagged 2 2 2
MIRT647394 FAM181B family with sequence similarity 181 member B 2 2
MIRT647447 SIX6 SIX homeobox 6 2 2
MIRT647455 MC2R melanocortin 2 receptor 2 2
MIRT647616 IGSF9B immunoglobulin superfamily member 9B 2 2
MIRT648105 LRRFIP1 LRR binding FLII interacting protein 1 2 2
MIRT648358 AKIP1 A-kinase interacting protein 1 2 2
MIRT649541 VAMP8 vesicle associated membrane protein 8 2 2
MIRT650687 CD82 CD82 molecule 2 2
MIRT650707 KRT32 keratin 32 2 2
MIRT651055 ZNF579 zinc finger protein 579 2 2
MIRT651541 WNK1 WNK lysine deficient protein kinase 1 2 2
MIRT651588 WDR26 WD repeat domain 26 2 2
MIRT651634 WASF3 WAS protein family member 3 2 2
MIRT651739 VEGFB vascular endothelial growth factor B 2 2
MIRT651836 USP37 ubiquitin specific peptidase 37 2 2
MIRT652239 TRAPPC10 trafficking protein particle complex 10 2 2
MIRT652888 SYVN1 synoviolin 1 2 2
MIRT652897 SYT2 synaptotagmin 2 2 2
MIRT652937 SYNGR1 synaptogyrin 1 2 2
MIRT652963 SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 2 2
MIRT653469 SLC4A1 solute carrier family 4 member 1 (Diego blood group) 2 2
MIRT653580 SLC35B3 solute carrier family 35 member B3 2 2
MIRT653626 SLC30A3 solute carrier family 30 member 3 2 2
MIRT653669 SLC26A7 solute carrier family 26 member 7 2 2
MIRT653921 SERPINC1 serpin family C member 1 2 2
MIRT654247 RIMS4 regulating synaptic membrane exocytosis 4 2 2
MIRT654269 RGS17 regulator of G protein signaling 17 2 2
MIRT654347 RBM27 RNA binding motif protein 27 2 2
MIRT654547 RAB1A RAB1A, member RAS oncogene family 2 2
MIRT654617 PTPRM protein tyrosine phosphatase, receptor type M 2 2
MIRT654732 PRLR prolactin receptor 2 2
MIRT654749 PRKCB protein kinase C beta 2 2
MIRT654930 POLR3D RNA polymerase III subunit D 2 2
MIRT655446 PALM2-AKAP2 PALM2-AKAP2 readthrough 2 2
MIRT655562 P2RX7 purinergic receptor P2X 7 2 2
MIRT656527 MAGT1 magnesium transporter 1 2 2
MIRT656861 KIN Kin17 DNA and RNA binding protein 2 2
MIRT657149 ITGA1 integrin subunit alpha 1 2 2
MIRT657408 HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 2 2
MIRT657436 HHIP hedgehog interacting protein 2 2
MIRT657700 GPC5 glypican 5 2 2
MIRT657863 GJD2 gap junction protein delta 2 2 2
MIRT658049 FUT11 fucosyltransferase 11 2 2
MIRT658094 FOXO1 forkhead box O1 2 2
MIRT658147 STXBP2 syntaxin binding protein 2 2 2
MIRT658179 FBXO9 F-box protein 9 2 2
MIRT658492 EXOC7 exocyst complex component 7 2 2
MIRT658499 EXOC5 exocyst complex component 5 2 2
MIRT658680 EMP2 epithelial membrane protein 2 2 2
MIRT658814 EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 2 2
MIRT659024 DHTKD1 dehydrogenase E1 and transketolase domain containing 1 2 2
MIRT659164 DCTN5 dynactin subunit 5 2 4
MIRT659417 COL4A4 collagen type IV alpha 4 chain 2 2
MIRT659626 CDON cell adhesion associated, oncogene regulated 2 2
MIRT659716 CCDC93 coiled-coil domain containing 93 2 2
MIRT660019 C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 2 2
MIRT660043 C15orf61 chromosome 15 open reading frame 61 2 2
MIRT660349 BBX BBX, HMG-box containing 2 2
MIRT660791 AKAP2 A-kinase anchoring protein 2 2 2
MIRT660946 ACER3 alkaline ceramidase 3 2 2
MIRT661286 EPPIN epididymal peptidase inhibitor 2 2
MIRT661335 TBC1D15 TBC1 domain family member 15 2 2
MIRT661568 EPHX2 epoxide hydrolase 2 2 2
MIRT661635 UGT2B28 UDP glucuronosyltransferase family 2 member B28 2 2
MIRT661644 EPPIN-WFDC6 EPPIN-WFDC6 readthrough 2 2
MIRT661740 DTHD1 death domain containing 1 2 2
MIRT664290 C15orf40 chromosome 15 open reading frame 40 2 2
MIRT664578 CD44 CD44 molecule (Indian blood group) 2 2
MIRT664749 SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 2 2
MIRT665300 ZBTB38 zinc finger and BTB domain containing 38 2 2
MIRT666755 RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 2 2
MIRT668007 HCFC2 host cell factor C2 2 2
MIRT668745 DIO2 iodothyronine deiodinase 2 2 2
MIRT668871 CRY2 cryptochrome circadian clock 2 2 2
MIRT669122 CD84 CD84 molecule 2 2
MIRT669140 CD200 CD200 molecule 2 2
MIRT671844 PDE3A phosphodiesterase 3A 2 4
MIRT675259 LPP LIM domain containing preferred translocation partner in lipoma 2 2
MIRT685148 TACR3 tachykinin receptor 3 2 2
MIRT686088 PNPLA3 patatin like phospholipase domain containing 3 2 2
MIRT698994 SPAG9 sperm associated antigen 9 2 2
MIRT704256 DHCR24 24-dehydrocholesterol reductase 2 2
MIRT707224 STAM signal transducing adaptor molecule 2 2
MIRT708402 GRIN2A glutamate ionotropic receptor NMDA type subunit 2A 2 2
MIRT710458 METTL15 methyltransferase like 15 2 2
MIRT710869 B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 2 2
MIRT711130 CYYR1 cysteine and tyrosine rich 1 2 2
MIRT711188 PIGG phosphatidylinositol glycan anchor biosynthesis class G 2 2
MIRT711604 LHX5 LIM homeobox 5 2 2
MIRT712518 ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 2 2
MIRT713086 ZG16 zymogen granule protein 16 2 2
MIRT713245 SLC22A3 solute carrier family 22 member 3 2 2
MIRT714209 MRE11A MRE11 homolog, double strand break repair nuclease 2 2
MIRT714966 N4BP2 NEDD4 binding protein 2 2 2
MIRT715286 TXNL1 thioredoxin like 1 2 2
MIRT715440 RGS6 regulator of G protein signaling 6 2 2
MIRT715635 ZBTB8B zinc finger and BTB domain containing 8B 2 2
MIRT716055 C1orf210 chromosome 1 open reading frame 210 2 2
MIRT716895 BTN3A2 butyrophilin subfamily 3 member A2 2 2
MIRT716988 GPR155 G protein-coupled receptor 155 2 2
MIRT717086 EBF4 early B-cell factor 4 2 2
MIRT717172 UCHL3 ubiquitin C-terminal hydrolase L3 2 2
MIRT717666 THBS2 thrombospondin 2 2 2
MIRT717673 CDC42BPA CDC42 binding protein kinase alpha 2 2
MIRT717731 FGF1 fibroblast growth factor 1 2 2
MIRT718685 FZD2 frizzled class receptor 2 2 2
MIRT718907 GALR1 galanin receptor 1 2 2
MIRT719114 MAML1 mastermind like transcriptional coactivator 1 2 2
MIRT719699 STX6 syntaxin 6 2 2
MIRT719833 C22orf24 chromosome 22 open reading frame 24 2 2
MIRT719892 RRP36 ribosomal RNA processing 36 2 2
MIRT720159 POU2F2 POU class 2 homeobox 2 2 2
MIRT720310 CSRNP3 cysteine and serine rich nuclear protein 3 2 2
MIRT720718 RAPGEF6 Rap guanine nucleotide exchange factor 6 2 2
MIRT721982 RAD50 RAD50 double strand break repair protein 2 2
MIRT722357 BAG2 BCL2 associated athanogene 2 2 2
MIRT722552 FGFR1OP FGFR1 oncogene partner 2 2
MIRT723274 TAL2 TAL bHLH transcription factor 2 2 2
MIRT723795 MUC17 mucin 17, cell surface associated 2 2
MIRT723805 BDKRB2 bradykinin receptor B2 2 2
MIRT724133 MT1A metallothionein 1A 2 2
MIRT724520 LRP6 LDL receptor related protein 6 2 2
MIRT724538 ABCG5 ATP binding cassette subfamily G member 5 2 2
MIRT735269 Sirt4 sirtuin 4 4 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-130b N-ethyl-N-nitrosourea NULL 12967 Quantitative real-time PCR mouse liver 21029445 2010 up-regulated
miR-130b Diethylstilbestrol approved 448537 Microarray mammosphere-derived epithelial cells (MDEC) 19549897 2009 down-regulated
miR-130b Formaldehyde NULL 712 Microarray Human lung epithelial cells (A549) 21147603 2011 down-regulated
miR-130b Goserelin approved 47725 Microarray prostate 22674191 2012 down-regulated
miR-130b Ginsenoside Rh2 NULL 119307 Microarray NSCLC cell line A549 23152132 2013 up-regulated
miR-130b Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 down-regulated
miR-130b Comfrey NULL 6440495 Microarray rat liver 21370286 2011 up-regulated
miR-130b Chaihu Shugan San NULL NULL Microarray hippocampus 23947143 2013 down-regualted
miR-130b Perfluorooctane sulfonate NULL 74483 Microarray zebrafish embryos 20878907 2011 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-130b Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (SGC-7901)
hsa-mir-130b Imatinib 5291 NSC743414 approved sensitive High Chronic Myelogenous Leukemia tissue
hsa-mir-130b Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-mir-130b Cisplatin 5460033 NSC119875 approved resistant cell line (SGC-7901)
hsa-miR-130b-5p Doxorubicin 31703 NSC123127 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-130b-5p Verapamil 2520 NSC272366 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-130b-5p Paclitaxel 36314 NSC125973 approved resistant High Laryngeal Cancer cell line (Hep2)
hsa-miR-130b-5p Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (H358, H1993)
hsa-miR-130b-5p Paclitaxel 36314 NSC125973 approved sensitive High Non-Small Cell Lung Cancer cell line (H358, H1993)
hsa-miR-130b-5p Cisplatin 5460033 NSC119875 approved sensitive Low Cervical Cancer tissue
hsa-miR-130b-5p Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (AsPC-1)
hsa-miR-130b-5p Taxol 36314 NSC125973 approved resistant Low Nasopharyngeal Cancer cell line (5-8F, CNE-1)
hsa-miR-130b-5p Neferine 71531543 resistant Low Nasopharyngeal Cancer cell line (5-8F, CNE-1)
hsa-miR-130b-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-130b-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-miR-130b-5p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-130b-5p Tamoxifen 2733525 NSC180973 approved resistant cell line (TamR1)
hsa-miR-130b-5p Tamoxifen 2733525 NSC180973 approved resistant cell line (TamR4)
hsa-miR-130b-5p Cisplatin 5460033 NSC119875 approved resistant cell line (IGROV-1)
hsa-miR-130b-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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