miRTarBase - #MIRT039002


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pre-miRNA Information
pre-miRNA hsa-let-7a-1   
Genomic Coordinates chr9: 94175957 - 94176036
Synonyms LET7A1, MIRNLET7A1, let-7a-1, MIRLET7A1
Description Homo sapiens let-7a-1 stem-loop
Comment let-7a-3p cloned in has a 1 nt 3' extension (U), which is incompatible with the genome sequence.
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-let-7a-3   
Genomic Coordinates chr22: 46112749 - 46112822
Synonyms LET7A3, MIRNLET7A3, let-7a-3, MIRLET7A3
Description Homo sapiens let-7a-3 stem-loop
Comment let-7a-3p cloned in has a 1 nt 3' extension (U), which is incompatible with the genome sequence.
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-let-7a-3p
Sequence 57| CUAUACAAUCUACUGUCUUUC |77
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 5 9 + 94176017 29233923 MiREDiBase
A-to-I 5 22 + 46112804 29233923 MiREDiBase
A-to-I 12 22 + 46112811 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs972845958 1 dbSNP
rs781681931 2 dbSNP
rs748585376 3 dbSNP
rs779353569 6 dbSNP
rs1198423693 8 dbSNP
rs970921980 8 dbSNP
rs372596018 9 dbSNP
rs770208205 10 dbSNP
rs1453867589 11 dbSNP
rs1399588338 15 dbSNP
rs1219969167 16 dbSNP
rs1265084977 18 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TRIM33   
Synonyms ECTO, PTC7, RFG7, TF1G, TIF1G, TIF1GAMMA, TIFGAMMA
Description tripartite motif containing 33
Transcript NM_015906   
Other Transcripts NM_033020   
Expression
Putative miRNA Targets on TRIM33
3'UTR of TRIM33
(miRNA target sites are highlighted)		 
>TRIM33|NM_015906|3'UTR
   1 AATGACATGGATTTAAATCAATTGTTTAAAAAAAAAAAAACGAAAAAAAAAAAAAAAACACAAAAAACCCAGAAAACTTT
  81 TAAGTGTTGCTGGAATATCCTGCCTACAGTGGGCACCTCCTTGAAGAAGCTGATAGCTTTTACACAGTATTAGATTGAAA
 161 TAATGGACAGAAACACATTCTTGTCAAGAAAGGGGGAGAGAAGTCTGTTTGCAAGTTTCAAAGCAAAAAGCAAAAGTGAA
 241 ATGATTTGAGGATTTCTGTTCTAATGGAGATGATTCTCTGATTGTTAGAAATGGCAAATATTGATGATTGTGTGCTATTG
 321 ATTGGTGCAGGATACTTGGTATACGAGTAAATACTTGAGACTCGTGTCACTTGATAAATTTTCTTTTTGGACTAGGTCGC
 401 ACAGTTATTAAAACAACTTTTAACCCTCCCCCTTCACACACATACATATCAGGTTGTTTTCTAGTTAAAAACCCAAGTAG
 481 CTCAGATTCTACTTTAATGTCAGTGCAGATTTGCATTGAATCATGCCATTATGTTTTTTCTCATTTTTATGCTGTTGGGT
 561 CTTAGTTTTTAAATTGATATAAAGAACTCAGCAATGGTTTTATTTTCTACTCATACTTAGGGTTTAGGAAACACTACCAC
 641 TAGTTATCATTTAATCAACTTCAATGGTCTACTGAAACAAAAATGGTAACTTTTCATTAGTGGATTATTTAGAGTTATAG
 721 TAGTTGTTTCCAGAAAACACTTCCTCACAATTGTACTTCCCAATCAAATCATGTGATCATACAGTTATTCCCATGAAAGG
 801 CAGAATGTTTGTTTCAAAATTAATCTAGTTTTCTGTACATTTAAATTTGAGAAGGTGACAACTGGCTCTTTTCCAGTCTT
 881 CCTTCATGTCAGTTTTCTGATAGACCACTATTGGCAAACAGTATCTGTCAACTACCAAATGTGTAAAATTTTCTGTATTT
 961 CACTTTGTCTTATTTGTAAATAGTGAACTAAAACTTTTGGCAGATCAGCAACATTTGCTGAGCCTGTTTTTTAAGCTAAT
1041 GTGTATTCTTACTAATGTTCCTATCAAGAATGGATTTGTAATATATGCTGTCTATTTCTAATGTTCACATTCATATTTTG
1121 AGGTTCTATCTTATTTTAATAGAGAACAGACTTCTCAAAAAATCTTCAGAAGCAGCTTATTATTGAAATATCGAAATATT
1201 GAAATAAACCCGGTGGGGTTAGATTACTCATCTGTCCACCAAGTGGGACATTTGCATGGACTGGGGGCTTAAAGGACTTA
1281 GAAGAGACCTGTAAGTAAATCCTGAAAATGAGCCAATCCCCACTTGAATGGTTACTGGAGTAAACCCACCTTTACCACCC
1361 CAATTACAGCACCCGAGGCCGATAAACCAACTTGGCTCTGGTTCATTTTTCTTTTCTTCATTTGTGATGCTCAGATTCAA
1441 AATGTGTGTTCTACACTGTTACAGGCTTCTCTTTTGTTTGATTAAAGATTTTAGTCCTACTTTTGTATGGACACATTAGA
1521 ATATTCAGAGACCAAAATAGAAGAATTTGCTGTTAGATATTTTTCAGAAGTCAGCAGATTTGTGGCAAATCATTTATTTG
1601 CCTTTTTAAAAATTCATTTAAGCAGTTCAGAGAGTAGACTACTCAGAAAATTATTTCACGTAATTGTCTAAGAGGTCAAT
1681 ATTTTTTAATGCATATTGAATCAAATAAAGTGCTCTAAAGAAATTATTATACAAATTCCTTTGGGTTGTTTTTCTTTTCT
1761 TAACAAGGGGTGGGGGTAAACAGGAATATGATTCAGGCTTTCTGGTTGTGTATTTAAAGAGTATTGATTTTATTATTACT
1841 ATTGATTTACTTTATTCCTGGCTTCCTTTTCACTTTTCTTTCAATTTTTAAAAAATAATTTAAGCCGTTGAAAATATACC
1921 AAACTGTTGAAACATTTTACTCAAATTTTAAATTCCTAAAAATGTTTTTTAATAAGAGGGAGAAAATTATTTAAAAATAC
2001 TTATGCCTATGCCAATTTCCCTCTTTTTTCACAAAATCCATGATTTCAGTTTGTAAGTAGACATATATCTAAGGGCACAT
2081 TTTTGGAAAGTGAGGAATAGCAGCAGTATAACTTCATTTTGTCAGGCCTTTGAGTTCTAATATTTTGTATTGCTCTTCAA
2161 ATGGATCCTTTTAAAAAAATTGTAGATAATGAGTCATAAATAGATTCTGCCAACTGAGGGGAGAAACATTTTAAGTAAAT
2241 ATTTTTCAGTATTTGGGGCCTTAAAAAATAATTGTGTTTCCTTAAAATTACATGTTAGATAGAGTTTTTAGGTTTTTTTG
2321 GTTTTAAGATTGGTTAAAGCAATTTAAAAGCCACTTTTTTGTCAACATTTAATAGCCTCCACTTCTGTTAAGATAATGTA
2401 TACTGCTGAGGAATTACTATTAATAGCTATCAACATACCACCATTAAATTAAGGTATTCACTTTAGATTTTTTATTAAAG
2481 CTTTTTTCTTGCACACTGATCGTTGTGTTTCTAAGCTGATTTTTTCAGCTCTAATATACCTATGGTTAAAAAGTATAAAA
2561 ACTTAAATTGATATTTAGATATATGTTTTCCTATTAGTTTATGTTTTAAAAAGACAAAATTGTATCTGTCAGTCCCTGAA
2641 GGCAGTTTGTTTTTATACTCTCTCACATTTGTATTTGTTTTTTAAATGGCAGTATTTTAGAAGATTTGGAGAAAAGTCCA
2721 CATAATAATGTTTTCTTAAAAGCTTTTAAAGTTTTTGCTGTACTTCAATTTACTTCTTCCATCAGAAAACTAAGAACAAA
2801 GTGTTGCTCAGTCTGTTCCGCTGACCTAAATTTGTGTTTTCAGCACTTGGCTCAGCCAATTCACTGAGTGAAGGAATTGC
2881 TTTATGAGGCAAAGCATGTGAAAGTTCTAAAGTATGGTTAGATTGTAGGTCGTGCTCTATATGGAAACATCAAACCATTA
2961 CTACAGAGAAATGATAAGGCATTGGATCCACTATTGAAATTATTATTTTTGGATCAACAAGTTGGTACTTTCTGACTTCT
3041 GTATCTTAACATAAGGGAATTTTAGGTAATGCTAAGTCAGTTGTCTCATTTTTTGTGATAAGTTTTGGAATTTTTAGTTA
3121 ATTGAAATAAATAATGCTTTTAAATAGAAGTAAAAGGTTTATAAGTGTGCAAATTGTAGATTTATCAATTACCTCAGCAG
3201 GTATCCTGCCATGTAATTATTAGTGATTAGTGTTAATAAGATAATAGATTCAGGTCTTCCAACTATGCCCTTGGATTGTG
3281 GCCTACTGTATGTTATTAAATGGTCTCTTACTATCCAAAATGGGAGTAGATGCTGTGGCCCCGTCTCCCTTGGCTTTTAC
3361 GTCCCATATCCACCCCCATTCATGTACAACATGTGAAATATAAAAATCTCATTTCTTGTCAAAATCAGCACTGCTTATTT
3441 GCATACTCAGCATCGGATCAGTGAGTAGTTTTATAAAAAATCCACGCACCCAACTCCCTTAGTTAAAACAGATTCTTAAT
3521 TCATACCATGAATTCTTAATTTCTGTACCATCTATGTTAATGATCTGCTGAAGGTGACTCAAGATTTTCAAGGTGTAATA
3601 CAGTTTGATCATGTACCGGACCTGGATATTTAATTTTTTTTCCCTCACAGTTAATCTCCTCCTTGATAAAGCAATAACAC
3681 TGCTTTGAGTCTGTTGCCTAATAGCATGTCAGAATCCTCTCCTGGATGGTGATTTTATAGGAAAGTTTGTATGCATATCA
3761 CCCAGTCTATCTTTTAAAAATTAAGAAATTTAAATGTATGCTGGAAGTAATGACACTATATTGTGGCATTTTATTTTAAA
3841 AATTGGGGAAAGTTGCATATTTTTTTAAAAGTAAGTGTTTGAGTAAAAAAATTGAAGGTACTTTTTTAAGGAAAAAAATT
3921 TATATGCCACAGTTTACATAGACATTTCAGATTCAACACGTACTCTTGAATATAATGGTTTCTTTTACTTGGTCAAAATG
4001 CATGTATAGCATTTCTTTCATCTTAGTTCCTTGTGTTTGCCTATGTGGTCCTTTATATATTTTTTATTGTATCGAAGAAA
4081 CAAAACTATCTTCAAAAATAAGTTAATTTGGATATATTTGTCATATCAAACTACAAAGTGTACAAAGTTAAGTTTAGCCC
4161 TTTTCTAGAAAGTGATCTTTAAAATTAAAAATGCTCCTCTTTTAAATTCACCAAATTTATGTGTGGGAAGGCACCAAAAT
4241 GATTTTGTAAGTGCCACTGCAATATTCCCTTTCAAGTGTGGCCTAAATTTCAATCTTAAGGATGGAATGCATGTCTGCTC
4321 CTTGTTCTGAAAAATGTAGGCATCTACTACATTTTAAAACACAGTGAAACATATACATAAGCCTATAAAAAAAGATTTGT
4401 GCAATTTGAAAGCCTGTTAATTTTTTATGTAGACATACCTACACACGAAAGGGTTAAATTCACAGCCTTACTAGTTCCTT
4481 GCTTCCAGTATTTCAATTGGTCTCCTCCCCTCATTATTATTATTACTACTAGTACTATTATTTTTGCACATAGTTAACTG
4561 CCCTTCAATATGATTCTTAAAAAGTGCTGTTTCTGTGGTATCGTATTCTCTAAATAATCATATTTAATTTTTTAAAACAA
4641 GGTTGCAGTTTCTAATTGTTTCGTTCCTGTGTTTTTGCTGGTGTGTAATAAAAGCAAGTTTTTTCTTTTCATGGTTATTT
4721 AATACATTAGCTGCCTGTAAATAATTCTTGTTATAATGCTCTGGAATGTGTTGTAGAAGTTGTATTAGATTAGTTTTAAA
4801 CCCTTGTTTGAAAGCCACATTGTTTTGGTTATTTCTATTAAATTAGAAAATTGAAAAAGTTTTCAAATGAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cuUUCUGUCAUCUAACAUAuc 5'
            ||||||  | |||||||  
Target 5' aaAAGACA--AAATTGTATct 3'
 2609 - 2627 147.00 -9.20
2 
miRNA  3' cuUUCUGUCAUCUAACAUAUc 5'
            |:|| |||   ||||||: 
Target 5' atAGGAAAGT---TTGTATGc 3'
 3737 - 3754 140.00 -6.50
3 
miRNA  3' cuuucuguCAUCU--AACAUAuc 5'
                  |||||  ||||||  
Target 5' aatgtgttGTAGAAGTTGTATta 3'
 4765 - 4787 135.00 -6.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31572509 39 COSMIC
COSN19658816 41 COSMIC
COSN16262607 42 COSMIC
COSN20095209 42 COSMIC
COSN28755001 43 COSMIC
COSN30507128 53 COSMIC
COSN17133435 54 COSMIC
COSN23240430 57 COSMIC
COSN20043502 59 COSMIC
COSN28870421 59 COSMIC
COSN18725908 61 COSMIC
COSN30179481 67 COSMIC
COSN26602813 71 COSMIC
COSN30505916 97 COSMIC
COSN30166157 103 COSMIC
COSN20883999 138 COSMIC
COSN31553882 176 COSMIC
COSN31567410 180 COSMIC
COSN20883265 230 COSMIC
COSN30174239 288 COSMIC
COSN30173999 292 COSMIC
COSN21306218 348 COSMIC
COSN8318227 528 COSMIC
COSN20095208 533 COSMIC
COSN31548790 937 COSMIC
COSN31550008 982 COSMIC
COSN15102763 985 COSMIC
COSN5353232 986 COSMIC
COSN5353231 995 COSMIC
COSN31489157 1060 COSMIC
COSN31579114 1068 COSMIC
COSN5353230 1138 COSMIC
COSN31546765 1332 COSMIC
COSN8887813 1375 COSMIC
COSN26644205 1405 COSMIC
COSN27097613 1416 COSMIC
COSN28132330 1881 COSMIC
COSN22271211 1890 COSMIC
COSN15118730 1933 COSMIC
COSN23515505 2023 COSMIC
COSN20095204 2172 COSMIC
COSN21061367 2591 COSMIC
COSN8887812 2985 COSMIC
COSN28640294 3019 COSMIC
COSN31520516 3124 COSMIC
COSN8635414 3285 COSMIC
COSN1087393 3290 COSMIC
COSN30177039 3307 COSMIC
COSN19461857 3328 COSMIC
COSN31778073 3360 COSMIC
COSN6503551 3398 COSMIC
COSN31960286 3629 COSMIC
COSN31577730 3703 COSMIC
COSN31539121 3717 COSMIC
COSN20931354 3897 COSMIC
COSN31517131 3920 COSMIC
COSN31537277 4000 COSMIC
COSN22757537 4009 COSMIC
COSN30176754 4022 COSMIC
COSN19003219 4090 COSMIC
COSN28808925 4111 COSMIC
COSN31484552 4127 COSMIC
COSN31550009 4417 COSMIC
COSN30175387 4447 COSMIC
COSN31482488 4514 COSMIC
COSN26584065 4603 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1428329354 1 dbSNP
rs1346774948 3 dbSNP
rs376201729 5 dbSNP
rs1311550014 10 dbSNP
rs1404670590 14 dbSNP
rs765959444 15 dbSNP
rs1167186780 17 dbSNP
rs746260941 18 dbSNP
rs1423109870 19 dbSNP
rs1464340220 20 dbSNP
rs781349530 21 dbSNP
rs1191817842 23 dbSNP
rs757816552 24 dbSNP
rs1243034133 25 dbSNP
rs1221370665 26 dbSNP
rs1450394541 27 dbSNP
rs1348288180 28 dbSNP
rs762336688 28 dbSNP
rs1275607194 29 dbSNP
rs551661313 30 dbSNP
rs1377964127 33 dbSNP
rs1334944937 35 dbSNP
rs1177399199 36 dbSNP
rs778219170 37 dbSNP
rs754546447 38 dbSNP
rs753328951 39 dbSNP
rs532092215 40 dbSNP
rs747740812 40 dbSNP
rs201845720 41 dbSNP
rs370757901 41 dbSNP
rs771112666 41 dbSNP
rs1343079967 42 dbSNP
rs149206135 42 dbSNP
rs760178727 42 dbSNP
rs1491225014 43 dbSNP
rs368785801 43 dbSNP
rs397964588 43 dbSNP
rs750263067 43 dbSNP
rs1371534086 45 dbSNP
rs767166695 45 dbSNP
rs761645510 46 dbSNP
rs781059132 47 dbSNP
rs964931982 47 dbSNP
rs754704148 48 dbSNP
rs774471267 50 dbSNP
rs766220955 51 dbSNP
rs1439552354 52 dbSNP
rs940124853 52 dbSNP
rs979453955 52 dbSNP
rs1211894998 53 dbSNP
rs201045277 54 dbSNP
rs1348846435 55 dbSNP
rs147717859 55 dbSNP
rs984644502 55 dbSNP
rs1395139733 56 dbSNP
rs200993921 56 dbSNP
rs1021069946 57 dbSNP
rs1312260880 58 dbSNP
rs58764175 58 dbSNP
rs1010030112 59 dbSNP
rs1177488190 59 dbSNP
rs1332852417 59 dbSNP
rs1491240300 59 dbSNP
rs66490349 59 dbSNP
rs867127404 59 dbSNP
rs1221295235 60 dbSNP
rs1412618980 60 dbSNP
rs373675604 60 dbSNP
rs12062175 61 dbSNP
rs1278248767 62 dbSNP
rs1326742726 63 dbSNP
rs1356120987 63 dbSNP
rs896320770 66 dbSNP
rs1301971698 67 dbSNP
rs951969258 67 dbSNP
rs1294018217 68 dbSNP
rs1317341061 68 dbSNP
rs369508223 68 dbSNP
rs1305121288 69 dbSNP
rs559884918 70 dbSNP
rs546622959 71 dbSNP
rs1255787674 72 dbSNP
rs55845467 72 dbSNP
rs1484501963 73 dbSNP
rs1466822838 77 dbSNP
rs1257657365 80 dbSNP
rs1405796202 82 dbSNP
rs1474786690 84 dbSNP
rs1166155094 90 dbSNP
rs1421573871 96 dbSNP
rs921906901 103 dbSNP
rs1035241114 121 dbSNP
rs1175120862 127 dbSNP
rs1373351674 128 dbSNP
rs974638805 131 dbSNP
rs1002089203 137 dbSNP
rs905147107 141 dbSNP
rs774129236 149 dbSNP
rs868150068 151 dbSNP
rs1467350464 154 dbSNP
rs1271938516 168 dbSNP
rs1340706824 169 dbSNP
rs1424670052 172 dbSNP
rs1219111510 175 dbSNP
rs1278683276 191 dbSNP
rs1350470297 192 dbSNP
rs1018634761 195 dbSNP
rs977718358 199 dbSNP
rs1445993323 207 dbSNP
rs1190414223 210 dbSNP
rs941069448 213 dbSNP
rs1475719806 214 dbSNP
rs1192898109 217 dbSNP
rs1393094618 226 dbSNP
rs1436344838 230 dbSNP
rs1174575634 236 dbSNP
rs1384535971 236 dbSNP
rs1399121265 237 dbSNP
rs1426815270 239 dbSNP
rs1320401334 242 dbSNP
rs1259504216 243 dbSNP
rs886741121 244 dbSNP
rs1301858976 251 dbSNP
rs1373734978 256 dbSNP
rs1046814067 258 dbSNP
rs1349534781 261 dbSNP
rs1202962080 264 dbSNP
rs1285795531 280 dbSNP
rs933712358 283 dbSNP
rs1183513161 285 dbSNP
rs1251062634 294 dbSNP
rs1483573367 295 dbSNP
rs1455483854 296 dbSNP
rs966486790 297 dbSNP
rs1022458698 298 dbSNP
rs1362965898 310 dbSNP
rs923477615 312 dbSNP
rs769089463 317 dbSNP
rs943501191 324 dbSNP
rs35834438 326 dbSNP
rs1323895521 327 dbSNP
rs979674994 331 dbSNP
rs1189615763 332 dbSNP
rs895288979 340 dbSNP
rs968046214 344 dbSNP
rs1236491024 345 dbSNP
rs913851082 348 dbSNP
rs1033918516 349 dbSNP
rs917962159 357 dbSNP
rs770631438 361 dbSNP
rs75224258 363 dbSNP
rs1232159793 364 dbSNP
rs184459962 369 dbSNP
rs575534644 371 dbSNP
rs1469786630 376 dbSNP
rs1249613028 380 dbSNP
rs1435848800 390 dbSNP
rs1035096589 396 dbSNP
rs1037003626 398 dbSNP
rs192165353 399 dbSNP
rs1162902932 401 dbSNP
rs1237088870 402 dbSNP
rs888577659 403 dbSNP
rs969190717 405 dbSNP
rs1016814560 422 dbSNP
rs1298084798 422 dbSNP
rs1394857692 425 dbSNP
rs1393501468 428 dbSNP
rs561495338 429 dbSNP
rs1335118282 442 dbSNP
rs1196317744 449 dbSNP
rs886797449 449 dbSNP
rs1449496608 451 dbSNP
rs1047142278 452 dbSNP
rs543718755 452 dbSNP
rs1233881325 453 dbSNP
rs1167568150 459 dbSNP
rs1250683802 462 dbSNP
rs1048950106 473 dbSNP
rs545333529 474 dbSNP
rs1337291699 476 dbSNP
rs1197351719 481 dbSNP
rs12071713 485 dbSNP
rs930523063 491 dbSNP
rs1370265594 495 dbSNP
rs1186040422 497 dbSNP
rs1165618140 500 dbSNP
rs997850776 501 dbSNP
rs921779455 503 dbSNP
rs1170443331 513 dbSNP
rs974544051 515 dbSNP
rs1463932386 516 dbSNP
rs900943683 518 dbSNP
rs1375181888 528 dbSNP
rs12057251 531 dbSNP
rs144710406 540 dbSNP
rs539687303 547 dbSNP
rs1396108683 554 dbSNP
rs1044002020 555 dbSNP
rs946932978 562 dbSNP
rs977790204 564 dbSNP
rs966768452 565 dbSNP
rs1266665233 573 dbSNP
rs913915374 576 dbSNP
rs113976766 580 dbSNP
rs1209068671 580 dbSNP
rs1282735977 584 dbSNP
rs1486085476 589 dbSNP
rs1022072593 594 dbSNP
rs1259688314 603 dbSNP
rs989615235 612 dbSNP
rs988575750 620 dbSNP
rs960720986 627 dbSNP
rs536679584 630 dbSNP
rs959131262 631 dbSNP
rs1033823728 634 dbSNP
rs781209291 635 dbSNP
rs980814470 636 dbSNP
rs41313993 637 dbSNP
rs557055034 639 dbSNP
rs1287813263 642 dbSNP
rs1382100051 651 dbSNP
rs1389855133 658 dbSNP
rs1383903581 663 dbSNP
rs1016700418 664 dbSNP
rs1393202739 664 dbSNP
rs1294136106 671 dbSNP
rs773423746 683 dbSNP
rs1384465649 684 dbSNP
rs1004251020 687 dbSNP
rs1161611740 712 dbSNP
rs1215284566 718 dbSNP
rs888434145 719 dbSNP
rs1441537123 720 dbSNP
rs747435535 725 dbSNP
rs1259084495 727 dbSNP
rs932739817 729 dbSNP
rs537200607 731 dbSNP
rs974335143 734 dbSNP
rs1252922248 750 dbSNP
rs1435694614 753 dbSNP
rs998301405 760 dbSNP
rs1038887910 761 dbSNP
rs78593296 763 dbSNP
rs911843824 766 dbSNP
rs1157885518 773 dbSNP
rs978399607 779 dbSNP
rs780133400 783 dbSNP
rs551598813 787 dbSNP
rs914911681 788 dbSNP
rs1006603690 815 dbSNP
rs1219426672 822 dbSNP
rs535001356 824 dbSNP
rs1355095423 825 dbSNP
rs1279310651 828 dbSNP
rs1237358065 829 dbSNP
rs1305123297 830 dbSNP
rs1247687721 832 dbSNP
rs889304541 834 dbSNP
rs989133075 835 dbSNP
rs566389598 837 dbSNP
rs959393566 850 dbSNP
rs1467547844 851 dbSNP
rs1043887739 860 dbSNP
rs1302247813 866 dbSNP
rs1404351827 884 dbSNP
rs1247705876 885 dbSNP
rs946891323 891 dbSNP
rs1176333847 900 dbSNP
rs1405352531 907 dbSNP
rs546260484 911 dbSNP
rs926336971 923 dbSNP
rs982285183 928 dbSNP
rs1421414001 935 dbSNP
rs1350317194 944 dbSNP
rs1385644264 955 dbSNP
rs529704823 959 dbSNP
rs1441207532 963 dbSNP
rs567344712 966 dbSNP
rs1375823019 967 dbSNP
rs1468439498 971 dbSNP
rs970862451 973 dbSNP
rs1052699288 974 dbSNP
rs1332740108 977 dbSNP
rs1235737374 984 dbSNP
rs1307361210 994 dbSNP
rs1015828820 997 dbSNP
rs1234914287 998 dbSNP
rs1199679886 999 dbSNP
rs1479943461 1005 dbSNP
rs1256255974 1012 dbSNP
rs1266112457 1023 dbSNP
rs1473934857 1033 dbSNP
rs1004854843 1043 dbSNP
rs1414459624 1047 dbSNP
rs1409247902 1053 dbSNP
rs1168095309 1067 dbSNP
rs754778942 1068 dbSNP
rs980840308 1071 dbSNP
rs948110858 1081 dbSNP
rs1312485177 1085 dbSNP
rs952963462 1088 dbSNP
rs1027407254 1090 dbSNP
rs1203685913 1094 dbSNP
rs550701478 1094 dbSNP
rs1361898300 1098 dbSNP
rs1213287139 1102 dbSNP
rs1347599641 1106 dbSNP
rs1343297918 1124 dbSNP
rs376690148 1128 dbSNP
rs984385450 1134 dbSNP
rs899956435 1139 dbSNP
rs1484450390 1141 dbSNP
rs1041140735 1147 dbSNP
rs750393089 1157 dbSNP
rs951245949 1170 dbSNP
rs1237509633 1176 dbSNP
rs1343919891 1181 dbSNP
rs146086735 1185 dbSNP
rs41296188 1191 dbSNP
rs115227797 1193 dbSNP
rs1172709772 1200 dbSNP
rs185696017 1211 dbSNP
rs945301571 1212 dbSNP
rs1334970104 1227 dbSNP
rs1317566103 1233 dbSNP
rs1429306752 1234 dbSNP
rs1398937868 1237 dbSNP
rs1366467544 1242 dbSNP
rs1006656463 1243 dbSNP
rs915129531 1250 dbSNP
rs1201784170 1251 dbSNP
rs1176940818 1252 dbSNP
rs535550393 1253 dbSNP
rs1445904876 1255 dbSNP
rs1011530515 1285 dbSNP
rs937678722 1286 dbSNP
rs1195157284 1288 dbSNP
rs926408875 1291 dbSNP
rs981814270 1302 dbSNP
rs970894128 1316 dbSNP
rs1392997001 1320 dbSNP
rs1241983277 1323 dbSNP
rs1173357353 1328 dbSNP
rs939596074 1330 dbSNP
rs1191651907 1333 dbSNP
rs906557871 1347 dbSNP
rs1444705067 1352 dbSNP
rs1390044392 1359 dbSNP
rs908724238 1367 dbSNP
rs113104023 1372 dbSNP
rs540858153 1374 dbSNP
rs375156834 1375 dbSNP
rs1215169322 1377 dbSNP
rs1027235757 1378 dbSNP
rs79114482 1380 dbSNP
rs964024291 1390 dbSNP
rs1221591507 1398 dbSNP
rs1269426052 1400 dbSNP
rs1428514353 1419 dbSNP
rs1465316647 1423 dbSNP
rs188028201 1432 dbSNP
rs543501393 1435 dbSNP
rs1337093185 1443 dbSNP
rs977091138 1444 dbSNP
rs1232530045 1452 dbSNP
rs1468749499 1454 dbSNP
rs1008333128 1458 dbSNP
rs903241054 1459 dbSNP
rs1412756219 1465 dbSNP
rs527612749 1466 dbSNP
rs1018193025 1474 dbSNP
rs1393416602 1475 dbSNP
rs985148719 1480 dbSNP
rs1328532980 1485 dbSNP
rs577761896 1491 dbSNP
rs1439521378 1506 dbSNP
rs1042623623 1507 dbSNP
rs1329215355 1512 dbSNP
rs968372430 1514 dbSNP
rs1232665016 1517 dbSNP
rs1403358142 1531 dbSNP
rs1172386889 1534 dbSNP
rs1410243119 1540 dbSNP
rs1358303262 1546 dbSNP
rs1210230666 1547 dbSNP
rs1009364740 1568 dbSNP
rs73003377 1571 dbSNP
rs1053701825 1576 dbSNP
rs937708216 1582 dbSNP
rs1009954423 1588 dbSNP
rs926274498 1592 dbSNP
rs1185811055 1606 dbSNP
rs1370717017 1615 dbSNP
rs1458822630 1616 dbSNP
rs1031140165 1630 dbSNP
rs1386435744 1636 dbSNP
rs1309461776 1638 dbSNP
rs1350650858 1640 dbSNP
rs1413640262 1643 dbSNP
rs1183328056 1650 dbSNP
rs1309894656 1655 dbSNP
rs1046024490 1659 dbSNP
rs182558043 1660 dbSNP
rs1337186096 1663 dbSNP
rs1207645874 1675 dbSNP
rs1275626276 1676 dbSNP
rs906816726 1683 dbSNP
rs1240199121 1698 dbSNP
rs566204960 1702 dbSNP
rs948088231 1707 dbSNP
rs1424943110 1710 dbSNP
rs888412104 1710 dbSNP
rs1193077051 1715 dbSNP
rs908245902 1717 dbSNP
rs983394574 1720 dbSNP
rs1048958124 1729 dbSNP
rs1169551653 1731 dbSNP
rs1370806263 1731 dbSNP
rs1433668349 1751 dbSNP
rs369435394 1758 dbSNP
rs930055161 1762 dbSNP
rs796240749 1767 dbSNP
rs931490618 1768 dbSNP
rs1396593173 1770 dbSNP
rs1294764149 1772 dbSNP
rs920198348 1773 dbSNP
rs556050687 1781 dbSNP
rs964264126 1786 dbSNP
rs1347469822 1788 dbSNP
rs1019638218 1797 dbSNP
rs986767159 1807 dbSNP
rs1299739689 1810 dbSNP
rs1205130145 1817 dbSNP
rs967459454 1821 dbSNP
rs1260270786 1829 dbSNP
rs764750950 1830 dbSNP
rs1189641963 1835 dbSNP
rs1394821791 1841 dbSNP
rs1020367804 1843 dbSNP
rs1378923799 1844 dbSNP
rs535828466 1844 dbSNP
rs1466106576 1857 dbSNP
rs1386388312 1867 dbSNP
rs1437140580 1869 dbSNP
rs893628145 1882 dbSNP
rs111614559 1896 dbSNP
rs914203910 1904 dbSNP
rs567282064 1906 dbSNP
rs955843354 1907 dbSNP
rs1312927089 1917 dbSNP
rs1164908649 1919 dbSNP
rs1032697346 1920 dbSNP
rs1238442801 1933 dbSNP
rs1326229731 1939 dbSNP
rs1266269062 1946 dbSNP
rs1331887446 1949 dbSNP
rs1209879840 1950 dbSNP
rs1035828260 1954 dbSNP
rs1406633231 1956 dbSNP
rs550638226 1961 dbSNP
rs190346766 1964 dbSNP
rs1269035960 1977 dbSNP
rs41314009 1981 dbSNP
rs571394725 1987 dbSNP
rs1443391029 1993 dbSNP
rs1458801703 1998 dbSNP
rs1023848441 2000 dbSNP
rs1393191607 2004 dbSNP
rs371494508 2006 dbSNP
rs1382520415 2007 dbSNP
rs551271939 2013 dbSNP
rs1012411388 2014 dbSNP
rs370474911 2015 dbSNP
rs1286951878 2016 dbSNP
rs1231425016 2019 dbSNP
rs994565165 2021 dbSNP
rs1272623983 2030 dbSNP
rs1490537289 2039 dbSNP
rs1320060018 2042 dbSNP
rs949052753 2057 dbSNP
rs1379112474 2060 dbSNP
rs1291201443 2061 dbSNP
rs773107185 2069 dbSNP
rs897263188 2078 dbSNP
rs1488662006 2080 dbSNP
rs1181213816 2083 dbSNP
rs886893055 2086 dbSNP
rs1041525554 2090 dbSNP
rs1125002 2095 dbSNP
rs931494441 2100 dbSNP
rs867325373 2103 dbSNP
rs1166426787 2107 dbSNP
rs559338399 2108 dbSNP
rs116707829 2110 dbSNP
rs1461751405 2114 dbSNP
rs1049675817 2115 dbSNP
rs1352790053 2118 dbSNP
rs975548897 2123 dbSNP
rs942940488 2132 dbSNP
rs912781437 2134 dbSNP
rs1293267718 2139 dbSNP
rs1372109626 2151 dbSNP
rs1230132748 2168 dbSNP
rs986840814 2171 dbSNP
rs397773186 2180 dbSNP
rs60897900 2180 dbSNP
rs1277415679 2181 dbSNP
rs967399241 2182 dbSNP
rs1365646447 2189 dbSNP
rs1272202340 2211 dbSNP
rs1483945591 2225 dbSNP
rs1205753223 2226 dbSNP
rs914460990 2229 dbSNP
rs1471497858 2231 dbSNP
rs1020817304 2237 dbSNP
rs1413989629 2243 dbSNP
rs955894499 2245 dbSNP
rs762683174 2251 dbSNP
rs1372776826 2257 dbSNP
rs1430846936 2263 dbSNP
rs1312762023 2278 dbSNP
rs1357951029 2281 dbSNP
rs529189706 2291 dbSNP
rs957662830 2296 dbSNP
rs1303503399 2298 dbSNP
rs1361441327 2300 dbSNP
rs928436355 2301 dbSNP
rs772834489 2304 dbSNP
rs1032150690 2309 dbSNP
rs981120073 2312 dbSNP
rs563338093 2313 dbSNP
rs1440638430 2319 dbSNP
rs879488215 2320 dbSNP
rs1237540086 2322 dbSNP
rs1001952076 2333 dbSNP
rs1186248148 2353 dbSNP
rs1391665442 2360 dbSNP
rs1220461320 2363 dbSNP
rs1450425873 2366 dbSNP
rs1172375689 2369 dbSNP
rs1423599734 2370 dbSNP
rs1416650564 2371 dbSNP
rs1335514259 2377 dbSNP
rs1344661424 2378 dbSNP
rs905157139 2393 dbSNP
rs1433036063 2395 dbSNP
rs34277810 2398 dbSNP
rs1366223770 2400 dbSNP
rs1288192612 2416 dbSNP
rs1012468274 2420 dbSNP
rs1274027213 2431 dbSNP
rs953022784 2435 dbSNP
rs1013233451 2438 dbSNP
rs1212110431 2453 dbSNP
rs1327823371 2461 dbSNP
rs1480923433 2461 dbSNP
rs1206307463 2467 dbSNP
rs1249439980 2471 dbSNP
rs1268232513 2471 dbSNP
rs1465070413 2472 dbSNP
rs1197806414 2473 dbSNP
rs1245330117 2475 dbSNP
rs1197427803 2477 dbSNP
rs1479235938 2477 dbSNP
rs886756722 2487 dbSNP
rs1047144040 2488 dbSNP
rs577698691 2491 dbSNP
rs1161474283 2493 dbSNP
rs1389562368 2494 dbSNP
rs558245471 2501 dbSNP
rs541234469 2502 dbSNP
rs561986416 2507 dbSNP
rs1349811517 2511 dbSNP
rs1041159673 2513 dbSNP
rs555745835 2515 dbSNP
rs1329311067 2517 dbSNP
rs1216159394 2518 dbSNP
rs1208847662 2526 dbSNP
rs547487625 2531 dbSNP
rs1287344212 2532 dbSNP
rs1453641862 2545 dbSNP
rs1316135342 2553 dbSNP
rs747984697 2555 dbSNP
rs1471895959 2556 dbSNP
rs1185050465 2557 dbSNP
rs889642215 2557 dbSNP
rs1224964033 2558 dbSNP
rs1161641509 2566 dbSNP
rs1393175932 2567 dbSNP
rs116058638 2574 dbSNP
rs1303537827 2576 dbSNP
rs1369792493 2579 dbSNP
rs912854196 2582 dbSNP
rs947185118 2585 dbSNP
rs1051338050 2586 dbSNP
rs946063153 2591 dbSNP
rs1282033665 2593 dbSNP
rs1053436072 2600 dbSNP
rs570410545 2601 dbSNP
rs1364618089 2603 dbSNP
rs1358040053 2611 dbSNP
rs934350604 2613 dbSNP
rs1274358032 2616 dbSNP
rs1289977732 2620 dbSNP
rs913251111 2621 dbSNP
rs928248719 2622 dbSNP
rs777263435 2624 dbSNP
rs9429746 2634 dbSNP
rs1370349515 2642 dbSNP
rs1179087221 2648 dbSNP
rs561353138 2662 dbSNP
rs915650890 2666 dbSNP
rs372379030 2667 dbSNP
rs1174322134 2669 dbSNP
rs1478846312 2679 dbSNP
rs1263692709 2687 dbSNP
rs1309728287 2688 dbSNP
rs1187025088 2689 dbSNP
rs1397150364 2694 dbSNP
rs1485542717 2694 dbSNP
rs927378020 2695 dbSNP
rs1394884046 2709 dbSNP
rs1240119860 2715 dbSNP
rs1331626425 2721 dbSNP
rs1205355219 2730 dbSNP
rs1246235988 2730 dbSNP
rs1296471492 2735 dbSNP
rs990973884 2743 dbSNP
rs1231105722 2746 dbSNP
rs78581320 2748 dbSNP
rs1221088920 2751 dbSNP
rs1258333720 2751 dbSNP
rs1443123366 2760 dbSNP
rs1308731582 2766 dbSNP
rs187094225 2768 dbSNP
rs1295749901 2769 dbSNP
rs372088781 2769 dbSNP
rs1382122261 2807 dbSNP
rs1170261128 2810 dbSNP
rs1373504673 2814 dbSNP
rs1360552651 2818 dbSNP
rs551476557 2819 dbSNP
rs772138281 2820 dbSNP
rs746134059 2829 dbSNP
rs1013520061 2834 dbSNP
rs1453877188 2837 dbSNP
rs1452775013 2844 dbSNP
rs1319414205 2845 dbSNP
rs961404620 2850 dbSNP
rs1437641276 2855 dbSNP
rs779043746 2859 dbSNP
rs1025314800 2866 dbSNP
rs1019603865 2878 dbSNP
rs1008218620 2880 dbSNP
rs1334990666 2881 dbSNP
rs1463777260 2884 dbSNP
rs889897014 2889 dbSNP
rs1379292536 2890 dbSNP
rs1258329262 2896 dbSNP
rs543062708 2898 dbSNP
rs995543551 2899 dbSNP
rs1028408008 2904 dbSNP
rs1466423110 2909 dbSNP
rs41310112 2912 dbSNP
rs1039466563 2915 dbSNP
rs1417331210 2917 dbSNP
rs1007095092 2922 dbSNP
rs1461610301 2923 dbSNP
rs892923724 2931 dbSNP
rs1157777379 2934 dbSNP
rs1385891591 2935 dbSNP
rs867358093 2939 dbSNP
rs1289138215 2948 dbSNP
rs1367302921 2954 dbSNP
rs542111576 2955 dbSNP
rs1385481439 2959 dbSNP
rs1051242425 2962 dbSNP
rs1053043431 2978 dbSNP
rs548951655 2979 dbSNP
rs934547775 2995 dbSNP
rs946333319 2999 dbSNP
rs906878309 3003 dbSNP
rs529128354 3007 dbSNP
rs1216736434 3008 dbSNP
rs1226088854 3014 dbSNP
rs1265118403 3015 dbSNP
rs563275916 3018 dbSNP
rs140332172 3020 dbSNP
rs1488009410 3021 dbSNP
rs749432045 3024 dbSNP
rs1054498716 3025 dbSNP
rs948374037 3036 dbSNP
rs1269296527 3047 dbSNP
rs1317782834 3050 dbSNP
rs1329092277 3053 dbSNP
rs915703023 3055 dbSNP
rs1480720683 3057 dbSNP
rs1181440818 3065 dbSNP
rs935991597 3075 dbSNP
rs1247105952 3080 dbSNP
rs984499412 3095 dbSNP
rs1382484685 3100 dbSNP
rs927410792 3106 dbSNP
rs980137519 3114 dbSNP
rs1335228534 3116 dbSNP
rs931508464 3135 dbSNP
rs1295652187 3139 dbSNP
rs1366650469 3145 dbSNP
rs780192359 3151 dbSNP
rs920049775 3151 dbSNP
rs1397507503 3152 dbSNP
rs971429247 3154 dbSNP
rs1460529848 3155 dbSNP
rs1352372809 3158 dbSNP
rs41301293 3160 dbSNP
rs961900341 3161 dbSNP
rs1320148342 3163 dbSNP
rs1224145509 3170 dbSNP
rs115198517 3172 dbSNP
rs1384345144 3175 dbSNP
rs1185201752 3179 dbSNP
rs1490465913 3184 dbSNP
rs1204309818 3187 dbSNP
rs1420453749 3188 dbSNP
rs564380975 3201 dbSNP
rs541527406 3211 dbSNP
rs114180130 3212 dbSNP
rs766189939 3213 dbSNP
rs1479379786 3241 dbSNP
rs995218750 3249 dbSNP
rs1306668659 3250 dbSNP
rs1028417904 3261 dbSNP
rs779039630 3265 dbSNP
rs1302330143 3268 dbSNP
rs892987197 3272 dbSNP
rs1230219325 3290 dbSNP
rs1293394760 3296 dbSNP
rs1227421415 3307 dbSNP
rs1018059727 3310 dbSNP
rs1006664983 3315 dbSNP
rs1223878730 3320 dbSNP
rs1309186741 3330 dbSNP
rs1205210471 3333 dbSNP
rs562305604 3343 dbSNP
rs1051282528 3348 dbSNP
rs1482015621 3357 dbSNP
rs758163767 3360 dbSNP
rs998683571 3361 dbSNP
rs907155358 3371 dbSNP
rs1167108013 3372 dbSNP
rs1045623681 3374 dbSNP
rs892079879 3376 dbSNP
rs542471096 3379 dbSNP
rs1357469651 3388 dbSNP
rs894113967 3390 dbSNP
rs1048806679 3393 dbSNP
rs1055101824 3401 dbSNP
rs930366867 3407 dbSNP
rs1336506427 3417 dbSNP
rs1364748667 3433 dbSNP
rs148085403 3436 dbSNP
rs905891317 3443 dbSNP
rs1044346036 3446 dbSNP
rs754316287 3447 dbSNP
rs903750291 3454 dbSNP
rs542318574 3455 dbSNP
rs1309886812 3456 dbSNP
rs917291504 3457 dbSNP
rs1263308236 3459 dbSNP
rs940201274 3464 dbSNP
rs1186345262 3475 dbSNP
rs182543851 3480 dbSNP
rs929791360 3482 dbSNP
rs1364906994 3485 dbSNP
rs537016390 3486 dbSNP
rs987016745 3487 dbSNP
rs1470964041 3493 dbSNP
rs577576005 3494 dbSNP
rs954028876 3501 dbSNP
rs557508942 3515 dbSNP
rs1455156607 3526 dbSNP
rs574791858 3528 dbSNP
rs1363961246 3531 dbSNP
rs190714960 3532 dbSNP
rs990261091 3547 dbSNP
rs962598837 3550 dbSNP
rs1274119329 3554 dbSNP
rs1471446578 3555 dbSNP
rs1017969401 3563 dbSNP
rs1283353229 3568 dbSNP
rs957712977 3569 dbSNP
rs1206406252 3575 dbSNP
rs1285947668 3576 dbSNP
rs985093145 3580 dbSNP
rs1221313924 3593 dbSNP
rs1245420254 3597 dbSNP
rs955112423 3616 dbSNP
rs538281293 3617 dbSNP
rs1411298030 3618 dbSNP
rs570841326 3627 dbSNP
rs1010431280 3644 dbSNP
rs1024186015 3645 dbSNP
rs1288351220 3647 dbSNP
rs1385965639 3650 dbSNP
rs776283359 3655 dbSNP
rs891939378 3664 dbSNP
rs1207201376 3674 dbSNP
rs756788453 3688 dbSNP
rs1000417346 3691 dbSNP
rs1347963499 3702 dbSNP
rs1012748265 3708 dbSNP
rs894164855 3709 dbSNP
rs1049176681 3714 dbSNP
rs1349296446 3716 dbSNP
rs906090703 3738 dbSNP
rs144680058 3747 dbSNP
rs764636333 3751 dbSNP
rs1226064454 3757 dbSNP
rs1350948644 3762 dbSNP
rs1227454996 3765 dbSNP
rs1288146770 3769 dbSNP
rs368785109 3769 dbSNP
rs761288766 3779 dbSNP
rs1223834363 3781 dbSNP
rs558109181 3796 dbSNP
rs1044376601 3802 dbSNP
rs549143647 3807 dbSNP
rs539323925 3818 dbSNP
rs1036103935 3822 dbSNP
rs940178157 3833 dbSNP
rs865930658 3847 dbSNP
rs535281932 3852 dbSNP
rs569583963 3857 dbSNP
rs1383120117 3872 dbSNP
rs1051362468 3877 dbSNP
rs369252145 3877 dbSNP
rs932859503 3885 dbSNP
rs549665168 3894 dbSNP
rs990577567 3903 dbSNP
rs895936569 3907 dbSNP
rs1335889804 3919 dbSNP
rs1344727001 3920 dbSNP
rs1190220678 3922 dbSNP
rs1446802890 3922 dbSNP
rs1048264919 3924 dbSNP
rs1361983982 3944 dbSNP
rs1383911199 3951 dbSNP
rs149313263 3959 dbSNP
rs1157827000 3960 dbSNP
rs1455300483 3962 dbSNP
rs186586596 3975 dbSNP
rs1198145751 3988 dbSNP
rs1251310466 4001 dbSNP
rs1441956975 4004 dbSNP
rs1185643842 4006 dbSNP
rs547523578 4008 dbSNP
rs775957796 4009 dbSNP
rs1446167587 4012 dbSNP
rs1176430260 4013 dbSNP
rs1163985097 4027 dbSNP
rs1389397741 4037 dbSNP
rs941267502 4043 dbSNP
rs1169623108 4055 dbSNP
rs911104057 4057 dbSNP
rs527765450 4063 dbSNP
rs1413438923 4066 dbSNP
rs1334227876 4067 dbSNP
rs764695794 4073 dbSNP
rs1244531936 4074 dbSNP
rs182570692 4075 dbSNP
rs1230221161 4080 dbSNP
rs138653599 4086 dbSNP
rs1261441875 4088 dbSNP
rs1344339587 4093 dbSNP
rs1198816409 4095 dbSNP
rs1265157241 4099 dbSNP
rs868466418 4105 dbSNP
rs1188230953 4108 dbSNP
rs191965224 4119 dbSNP
rs1027555585 4122 dbSNP
rs1247154755 4123 dbSNP
rs563129886 4124 dbSNP
rs186207539 4128 dbSNP
rs1195184751 4133 dbSNP
rs988982959 4142 dbSNP
rs1407692256 4144 dbSNP
rs577513565 4145 dbSNP
rs1325875792 4153 dbSNP
rs897454115 4158 dbSNP
rs1173632001 4160 dbSNP
rs1407740079 4161 dbSNP
rs1319521298 4165 dbSNP
rs1469978882 4165 dbSNP
rs1383208414 4167 dbSNP
rs1384299681 4177 dbSNP
rs955784731 4186 dbSNP
rs41313288 4191 dbSNP
rs1321488233 4197 dbSNP
rs1272074850 4198 dbSNP
rs1000280324 4209 dbSNP
rs1222295033 4217 dbSNP
rs906163264 4223 dbSNP
rs1285256916 4229 dbSNP
rs1327007040 4231 dbSNP
rs1208306563 4260 dbSNP
rs1023167356 4270 dbSNP
rs1484741017 4280 dbSNP
rs1206684431 4289 dbSNP
rs1317315705 4293 dbSNP
rs1432636677 4302 dbSNP
rs1008626006 4311 dbSNP
rs1014238414 4313 dbSNP
rs372969672 4314 dbSNP
rs759868040 4318 dbSNP
rs895787634 4319 dbSNP
rs1480496429 4321 dbSNP
rs1051292391 4327 dbSNP
rs932785914 4340 dbSNP
rs1047700831 4347 dbSNP
rs1455610695 4349 dbSNP
rs1469026568 4354 dbSNP
rs1422408526 4362 dbSNP
rs1390536966 4363 dbSNP
rs994004891 4372 dbSNP
rs534354970 4394 dbSNP
rs1169193080 4397 dbSNP
rs1346182169 4410 dbSNP
rs1475998484 4412 dbSNP
rs572070754 4422 dbSNP
rs899217064 4426 dbSNP
rs1038215014 4427 dbSNP
rs774623537 4432 dbSNP
rs941172541 4434 dbSNP
rs1462948493 4435 dbSNP
rs1244195072 4436 dbSNP
rs911169642 4436 dbSNP
rs1049652838 4438 dbSNP
rs1220109130 4438 dbSNP
rs1490354912 4439 dbSNP
rs1203267402 4446 dbSNP
rs1405246043 4447 dbSNP
rs933898253 4468 dbSNP
rs1275184134 4475 dbSNP
rs1368221273 4479 dbSNP
rs922272052 4483 dbSNP
rs1423163872 4495 dbSNP
rs529084716 4496 dbSNP
rs988461384 4503 dbSNP
rs955985620 4504 dbSNP
rs924597092 4505 dbSNP
rs1226161968 4512 dbSNP
rs750977375 4516 dbSNP
rs1375684420 4526 dbSNP
rs925721823 4526 dbSNP
rs977494943 4526 dbSNP
rs1312318833 4529 dbSNP
rs576514421 4532 dbSNP
rs1315514856 4537 dbSNP
rs555063409 4549 dbSNP
rs1357092286 4550 dbSNP
rs1293774388 4560 dbSNP
rs1330263134 4565 dbSNP
rs567856621 4568 dbSNP
rs1023198422 4570 dbSNP
rs917319193 4571 dbSNP
rs1396334010 4574 dbSNP
rs1177385565 4578 dbSNP
rs74437334 4589 dbSNP
rs1447050090 4595 dbSNP
rs1443101404 4598 dbSNP
rs569522492 4602 dbSNP
rs749302002 4603 dbSNP
rs762473820 4612 dbSNP
rs555983459 4619 dbSNP
rs1169006401 4620 dbSNP
rs1356315362 4637 dbSNP
rs539718727 4641 dbSNP
rs993476166 4642 dbSNP
rs1462586338 4645 dbSNP
rs1302427697 4661 dbSNP
rs777846363 4662 dbSNP
rs1037783283 4663 dbSNP
rs1005411240 4669 dbSNP
rs1316872304 4679 dbSNP
rs889640488 4682 dbSNP
rs1049559433 4694 dbSNP
rs1437298745 4696 dbSNP
rs11540548 4705 dbSNP
rs1213885643 4705 dbSNP
rs1270829786 4711 dbSNP
rs2879 4717 dbSNP
rs1204621798 4722 dbSNP
rs1308696470 4722 dbSNP
rs768538046 4723 dbSNP
rs922505035 4729 dbSNP
rs61810990 4731 dbSNP
rs973304353 4734 dbSNP
rs570684898 4754 dbSNP
rs1053236628 4755 dbSNP
rs1459695331 4766 dbSNP
rs1361564610 4773 dbSNP
rs188015577 4779 dbSNP
rs925735767 4783 dbSNP
rs184072569 4784 dbSNP
rs181041729 4810 dbSNP
rs1376434521 4814 dbSNP
rs1280943553 4816 dbSNP
rs1442564722 4819 dbSNP
rs1429132332 4824 dbSNP
rs529398572 4853 dbSNP
rs112032984 4855 dbSNP
rs1175449916 4858 dbSNP
rs1008553872 4859 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Flp-In T-REx 293-hAGO1 cells
Location of target site CDS
Original Description (Extracted from the article) ... Validation of interactions identified by CLASH suppports their reliability. ...

- Helwak A; Kudla G; Dudnakova T; Tollervey D, 2013, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cuUUCUGUC-A--UCUAACAUAUc 5'
            ||||||| |  || |  || | 
Target 5' gaAAGACAGATGAAGTTACTACAg 3'
 		5 - 28
Article - Helwak A; Kudla G; Dudnakova T; Tollervey D
- Cell, 2013
MicroRNAs (miRNAs) play key roles in gene regulation, but reliable bioinformatic or experimental identification of their targets remains difficult. To provide an unbiased view of human miRNA targets, we developed a technique for ligation and sequencing of miRNA-target RNA duplexes associated with human AGO1. Here, we report data sets of more than 18,000 high-confidence miRNA-mRNA interactions. The binding of most miRNAs includes the 5' seed region, but around 60% of seed interactions are noncanonical, containing bulged or mismatched nucleotides. Moreover, seed interactions are generally accompanied by specific, nonseed base pairing. 18% of miRNA-mRNA interactions involve the miRNA 3' end, with little evidence for 5' contacts, and some of these were functionally validated. Analyses of miRNA:mRNA base pairing showed that miRNA species systematically differ in their target RNA interactions, and strongly overrepresented motifs were found in the interaction sites of several miRNAs. We speculate that these affect the response of RISC to miRNA-target binding.
LinkOut: [PMID: 23622248]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
KICH 0.49 0.01 0.429 0.02 25 Click to see details
STAD -0.372 0.02 -0.515 0 32 Click to see details
PRAD 0.294 0.02 0.339 0.01 50 Click to see details
BRCA 0.146 0.09 0.145 0.09 84 Click to see details
CESC -0.955 0.1 -1.000 0.5 3 Click to see details
PAAD 0.76 0.12 0.800 0.1 4 Click to see details
LUAD -0.296 0.18 -0.357 0.13 12 Click to see details
ESCA 0.27 0.21 0.445 0.09 11 Click to see details
THCA 0.106 0.21 0.098 0.23 59 Click to see details
COAD -0.575 0.21 -0.600 0.2 4 Click to see details
KIRC 0.092 0.23 0.097 0.22 68 Click to see details
CHOL 0.183 0.32 0.133 0.37 9 Click to see details
LIHC -0.057 0.35 -0.085 0.28 49 Click to see details
HNSC 0.032 0.42 0.022 0.45 42 Click to see details
UCEC 0.029 0.45 -0.140 0.28 19 Click to see details
LUSC 0.011 0.47 0.072 0.33 38 Click to see details
BLCA 0.015 0.48 -0.073 0.39 18 Click to see details
KIRP -0.01 0.48 0.019 0.46 32 Click to see details
PCPG 1 0.5 1.000 0.5 3 Click to see details
PCPG 1 0.5 1.000 0.5 3 Click to see details
121 hsa-let-7a-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT038998 ARMC8 armadillo repeat containing 8 1 1
MIRT038999 SETD4 SET domain containing 4 1 1
MIRT039000 BTF3 basic transcription factor 3 1 1
MIRT039001 MIPOL1 mirror-image polydactyly 1 1 1
MIRT039002 TRIM33 tripartite motif containing 33 1 1
MIRT039003 CS citrate synthase 1 1
MIRT039004 SENP7 SUMO1/sentrin specific peptidase 7 1 1
MIRT055418 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 10
MIRT057681 LCOR ligand dependent nuclear receptor corepressor 2 8
MIRT061351 WEE1 WEE1 G2 checkpoint kinase 2 2
MIRT062174 WNK1 WNK lysine deficient protein kinase 1 2 2
MIRT071813 RNF11 ring finger protein 11 2 2
MIRT091374 EIF4A2 eukaryotic translation initiation factor 4A2 2 2
MIRT095107 SEC24A SEC24 homolog A, COPII coat complex component 2 2
MIRT098814 PPIL4 peptidylprolyl isomerase like 4 2 2
MIRT109534 KLHL15 kelch like family member 15 2 4
MIRT120263 GSK3B glycogen synthase kinase 3 beta 2 2
MIRT149839 LDLR low density lipoprotein receptor 2 6
MIRT164519 MSMO1 methylsterol monooxygenase 1 2 2
MIRT165879 CREBRF CREB3 regulatory factor 2 2
MIRT169899 HBP1 HMG-box transcription factor 1 2 4
MIRT182779 TOR1AIP2 torsin 1A interacting protein 2 2 2
MIRT193466 RORA RAR related orphan receptor A 2 2
MIRT226421 TP53INP1 tumor protein p53 inducible nuclear protein 1 2 2
MIRT334410 CREBZF CREB/ATF bZIP transcription factor 2 6
MIRT338286 SYF2 SYF2 pre-mRNA splicing factor 2 2
MIRT361627 TES testin LIM domain protein 2 2
MIRT406687 ZNF181 zinc finger protein 181 2 2
MIRT407768 MRPL35 mitochondrial ribosomal protein L35 2 2
MIRT449468 HAT1 histone acetyltransferase 1 2 2
MIRT467110 SRI sorcin 2 2
MIRT475099 IRF2BP2 interferon regulatory factor 2 binding protein 2 2 6
MIRT481671 ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2 2
MIRT493061 MTFR1 mitochondrial fission regulator 1 2 2
MIRT497923 BTG1 BTG anti-proliferation factor 1 2 2
MIRT498202 ACVR2B activin A receptor type 2B 2 2
MIRT503391 ASB11 ankyrin repeat and SOCS box containing 11 2 6
MIRT503862 UBXN2B UBX domain protein 2B 2 2
MIRT504368 ARID1B AT-rich interaction domain 1B 2 4
MIRT504991 ZNF652 zinc finger protein 652 2 2
MIRT505754 SENP1 SUMO1/sentrin specific peptidase 1 2 8
MIRT518102 ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 2 6
MIRT521930 PHF8 PHD finger protein 8 2 4
MIRT522139 NRBF2 nuclear receptor binding factor 2 2 6
MIRT522401 MYADM myeloid associated differentiation marker 2 4
MIRT523593 FZD5 frizzled class receptor 5 2 4
MIRT523944 E2F8 E2F transcription factor 8 2 4
MIRT524355 CREB1 cAMP responsive element binding protein 1 2 2
MIRT525140 ZNF256 zinc finger protein 256 2 2
MIRT527070 ABCC4 ATP binding cassette subfamily C member 4 2 2
MIRT527486 OCIAD1 OCIA domain containing 1 2 2
MIRT528129 PPP1R10 protein phosphatase 1 regulatory subunit 10 2 2
MIRT530528 ALG10B ALG10B, alpha-1,2-glucosyltransferase 2 2
MIRT531270 PPIL3 peptidylprolyl isomerase like 3 2 2
MIRT538898 BRI3BP BRI3 binding protein 2 2
MIRT541371 CDKN1B cyclin dependent kinase inhibitor 1B 2 2
MIRT541526 MGAT4C MGAT4 family member C 2 2
MIRT543776 RBM12B RNA binding motif protein 12B 2 4
MIRT543946 NCOA7 nuclear receptor coactivator 7 2 2
MIRT545156 GABRG1 gamma-aminobutyric acid type A receptor gamma1 subunit 2 2
MIRT545848 ZNF264 zinc finger protein 264 2 4
MIRT546064 VEZF1 vascular endothelial zinc finger 1 2 2
MIRT546481 SLC16A14 solute carrier family 16 member 14 2 4
MIRT551835 AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 2 2
MIRT551901 ACP1 acid phosphatase 1, soluble 2 2
MIRT552490 ZNF136 zinc finger protein 136 2 2
MIRT554206 SLC35A5 solute carrier family 35 member A5 2 2
MIRT554295 SIPA1L2 signal induced proliferation associated 1 like 2 2 2
MIRT555765 PCTP phosphatidylcholine transfer protein 2 2
MIRT558315 DSG2 desmoglein 2 2 2
MIRT563147 NOLC1 nucleolar and coiled-body phosphoprotein 1 2 2
MIRT566464 PGGT1B protein geranylgeranyltransferase type I subunit beta 2 2
MIRT567322 HMGB2 high mobility group box 2 2 2
MIRT567738 DLX2 distal-less homeobox 2 2 2
MIRT567892 CSTF2 cleavage stimulation factor subunit 2 2 2
MIRT570087 KANSL1L KAT8 regulatory NSL complex subunit 1 like 2 2
MIRT571136 TTC33 tetratricopeptide repeat domain 33 2 2
MIRT573534 MDM2 MDM2 proto-oncogene 2 2
MIRT574465 RPS16 ribosomal protein S16 2 2
MIRT574998 Phka1 phosphorylase kinase alpha 1 2 3
MIRT610202 CD99 CD99 molecule (Xg blood group) 2 4
MIRT612926 GPRIN3 GPRIN family member 3 2 2
MIRT615027 DUSP6 dual specificity phosphatase 6 2 2
MIRT617200 GREM1 gremlin 1, DAN family BMP antagonist 2 2
MIRT628720 ZNF585A zinc finger protein 585A 2 2
MIRT641491 POLA2 DNA polymerase alpha 2, accessory subunit 2 2
MIRT641663 PAPOLG poly(A) polymerase gamma 2 2
MIRT642216 RUVBL2 RuvB like AAA ATPase 2 2 2
MIRT654589 PURA purine rich element binding protein A 2 2
MIRT656136 MSH6 mutS homolog 6 2 2
MIRT656899 KIAA2018 upstream transcription factor family member 3 2 2
MIRT660136 BRPF3 bromodomain and PHD finger containing 3 2 2
MIRT660861 AFAP1 actin filament associated protein 1 2 2
MIRT676849 PHKA1 phosphorylase kinase regulatory subunit alpha 1 2 3
MIRT681479 DIP2A disco interacting protein 2 homolog A 2 2
MIRT682259 RS1 retinoschisin 1 2 2
MIRT685602 MYOM2 myomesin 2 2 2
MIRT686943 SFT2D3 SFT2 domain containing 3 2 2
MIRT694302 COPB2 coatomer protein complex subunit beta 2 2 2
MIRT694407 ALDH1A3 aldehyde dehydrogenase 1 family member A3 2 2
MIRT697280 ZNF800 zinc finger protein 800 2 2
MIRT698414 TM4SF1 transmembrane 4 L six family member 1 2 2
MIRT698989 SPAG9 sperm associated antigen 9 2 2
MIRT699766 SEMA4D semaphorin 4D 2 2
MIRT699928 RUFY2 RUN and FYVE domain containing 2 2 2
MIRT702113 MBNL1 muscleblind like splicing regulator 1 2 2
MIRT702373 KLF10 Kruppel like factor 10 2 2
MIRT702646 ITGA3 integrin subunit alpha 3 2 2
MIRT705713 ANAPC16 anaphase promoting complex subunit 16 2 2
MIRT717925 ZNF546 zinc finger protein 546 2 2
MIRT720839 C1orf52 chromosome 1 open reading frame 52 2 2
MIRT725033 NDUFAF7 NADH:ubiquinone oxidoreductase complex assembly factor 7 2 2
MIRT731448 APOBEC3A apolipoprotein B mRNA editing enzyme catalytic subunit 3A 1 1
MIRT733217 CCNG1 cyclin G1 2 0
MIRT734887 LIN28B lin-28 homolog B 1 0
MIRT735276 HMGA2 high mobility group AT-hook 2 2 0
MIRT735727 SYNCRIP synaptotagmin binding cytoplasmic RNA interacting protein 3 0
MIRT736087 RCVRN recoverin 1 0
MIRT736088 RHO rhodopsin 1 0
MIRT736103 TLR7 toll like receptor 7 1 0
MIRT736607 TPO thyroid peroxidase 2 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
let-7a Caudatin NULL 21633059 Quantitative real-time PCR gastric carcinoma cell lines 23708208 2013 up-regualted
let-7a XMD8-92 NULL 46843772 Microarray pancreatic ductal adenocarcinoma cell 24880079 2014 up-regulated
let-7a Hydroxamic acid HDACi LAQ824 NULL NULL Microarray breast cancer cell line SKBr3 16452179 2006 down-regulated
let-7a Hydroxamic acid HDACi LAQ824 NULL NULL Northern blot breast cancer cell line SKBr3 16452180 2006 down-regulated
let-7a Trichostatin A (TSA) NULL 444732 Microarray human pancreatic cancer cell line BxPC-3 19112422 2009 down-regulated
let-7a 17beta-estradiol (E2) approved 5757 Microarray MCF-7 breast cancer cells 19528081 2009 up-regulated
let-7a Etoposide approved 36462 Microarray Normal human fibroblasts (AG01522) 19633716 2009 down-regulated
let-7a Etoposide approved 36462 Quantitative real-time PCR Normal human fibroblasts (AG01522) 19633716 2009 down-regulated
let-7a Polylysine NULL 162282 Quantitative real-time PCR 293T(FLAG AGO2) cells 20529860 2010 down-regulated
let-7a Trypaflavine NULL NULL Quantitative real-time PCR 293T(FLAG AGO2) cells 20529860 2010 down-regulated
let-7a Formaldehyde NULL 712 Microarray Human lung epithelial cells (A549) 21147603 2011 down-regulated
let-7a Enoxacin approved 3229 Northern blot HCT-116 and RKO colon cancer cell lines 21368194 2011 up-regulated
let-7a Enoxacin approved 3229 Quantitative real-time PCR HCT-116 and RKO colon cancer cell lines 21368194 2011 up-regulated
let-7a Metformin approved 4091 Quantitative real-time PCR MCF-7 human mammary cancer cell line 21368581 2011 up-regulated
let-7a 5-Fluorouracil approved 3385 Microarray MCF-7 breast cancer cells 21506117 2011 up-regulated
let-7a Arsenic trioxide approved 14888 Quantitative real-time PCR acute promyelocytic leukemia 22072212 2012 up-regulated
let-7a Metformin approved 4091 Quantitative real-time PCR pancreatic cancer cells 22086681 2012 up-regulated
let-7a Metformin approved 4091 Quantitative real-time PCR pancreatic cancer cells 22086681 2012 up-regulated
let-7a CDF(analogues of curcumin) NULL NULL Quantitative real-time PCR pancreatic cancer cells 22108826 2012 up-regulated
let-7a Marine fungal metabolite 1386A NULL NULL Microarray MCF-7 breast cancer cells. 22159329 2012 down-regulated
let-7a Curcumin NULL 969516 Quantitative real-time PCR esophageal cancer cells 22363450 2012 up-regulated
let-7a 1,2,6-Tri-O-galloyl-beta-D-glucopyranose NULL NULL Microarray HepG2 hepatocarcinoma cells. 22506400 2011 up-regulated
let-7a Vitamin D3 approved 5280795 Quantitative real-time PCR Plasma 22594500 2012 up-regulated
let-7a Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse liver 19270793 2009 down-regulated
let-7a Budesonide approved 5281004 Microarray neonatal mice liver 20145010 2010 up-regulated
let-7a Budesonide approved 5281004 Microarray neonatal mice lung 20145010 2010 down-regulated
let-7a Phenethyl isothiocyanate(PEITC) NULL 16741 Microarray neonatal mice lung 20145010 2010 up-regulated
let-7a Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 down-regulated
let-7a Dexamethasone approved 5743 Quantitative real-time PCR primary rat thymocytes 20847043 2010 down-regulated
let-7a Perfluorooctane sulfonate NULL 74483 Microarray zebrafish embryos 20878907 2011 up-regulated
let-7a Hydroxychloroquine approved 3652 Quantitative real-time PCR mesangial cells 24121037 2013 down-regualted
let-7a Prednisone approved 5865 Quantitative real-time PCR mesangial cells 24121037 2013 down-regualted
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-let-7a-3p Gemcitabine 60750 NSC613327 approved resistant High Cholangiocarcinoma cell line (HuCCT1, HuH28)
hsa-let-7a-3p Docetaxel 148124 NSC628503 approved sensitive High Breast Cancer cell line (MDA-MB-231, MCF-7)
hsa-let-7a-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-let-7a-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-let-7a-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-let-7a-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-let-7a-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-let-7a-3p Fluorouracil 3385 NSC19893 approved sensitive cell line (HCT15)
hsa-let-7a-3p 4-Hydroxytamoxifen+Tamoxifen resistant cell line (LY2)
hsa-let-7a-3p Oxaliplatin 6857599 NSC266046 approved resistant cell line (IGROV-1)
hsa-let-7a-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-let-7a-3p Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-let-7a-3p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide sensitive cell line (Bads-200)

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