miRTarBase - #MIRT039242


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pre-miRNA Information
pre-miRNA hsa-mir-454   
Genomic Coordinates chr17: 59137758 - 59137872
Synonyms MIRN454, hsa-mir-454, MIR454
Description Homo sapiens miR-454 stem-loop
Comment The mature miRNA sequences were named miR-454-5p and miR-454-3p in .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-454-3p
Sequence 64| UAGUGCAAUAUUGCUUAUAGGGU |86
Evidence Experimental
Experiments Cloned
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN30529712 20 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1391884708 2 dbSNP
rs772555392 4 dbSNP
rs555225543 7 dbSNP
rs1450965019 11 dbSNP
rs779514158 12 dbSNP
rs771457463 18 dbSNP
rs377123764 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol FLNC   
Synonyms ABP-280, ABP280A, ABPA, ABPL, CMH26, FLN2, MFM5, MPD4, RCM5
Description filamin C
Transcript NM_001127487   
Other Transcripts NM_001458   
Expression
Putative miRNA Targets on FLNC
3'UTR of FLNC
(miRNA target sites are highlighted)		 
>FLNC|NM_001127487|3'UTR
   1 ATCCCAAAAGTGCCTCCCCAGCCTCAGCCCCCACCTCCAGCCACACACACATTACACACACACACACACACACACAAATG
  81 TGCCACACCCAGACACGCACAGAATCAGACACTACAAACACCTGCCTTGGGGGTGAAGTGAAGGCCCAGCCTCCCCACCC
 161 CACCGCGCCCCAGGGGTTGGAGGACCTTGTCTGTGTCAGGACAGTGTCCCTCCCTGGGAATGTGACATGAGGGCCGACTG
 241 GGGCCAGGCTCAGGGGCAGAGGCTGGGACACAAGGGGCTGGCGAGGGCTGCGAGGCCAGGGAAGCCCTGAGTTTCTGGCG
 321 GGGCTGAGCAGTGGGGGAGCATTGTGTTGTGGGTGTCTGTGTGTGAGGTCACCCTCAAACTGCACCGCCGGCCAGATACC
 401 CTCCTGACCCCGAGGACTTGGTCTGGTCTCTCTGGTGGCTACAACCCCAGAGTTTTAAGGACTTGGAAAGGAAAGCACAA
 481 TCAGAGAAGAAAACAGCCCCCGAACCAGCAGGAGTGGCCTGGCACATGGACCGGCCTGAGCGATGTGCACTCCACCCAAG
 561 CCAGGCTCCCAGGGGGCCTGATTTCTCTCTCACTGTCTCTTTTTTTAAAATGGTTGCACGGCTCTGCCCCATGGGGGGCC
 641 TTTTTTACACACTGCGAGGCCCAGCTTTCTAGGGGACTTTTGCACATGTCATGCAGCTCAGCTGGGAGCTGCTTAGGTGG
 721 AAAACTCCAAATAAAGTGCGGCTGTCGCAGAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ugGGAUAUUCGUUA-UAACGUGau 5'
            ::| |||  ||| :||||||  
Target 5' ttTTTTTAA--AATGGTTGCACgg 3'
 600 - 621 137.00 -6.10
2 
miRNA  3' ugGGAUAUUCGUU-AUAACGUGau 5'
            ::| ||:| :| | ||||||  
Target 5' gcTTTCTAGGGGACTTTTGCACat 3'
 664 - 687 137.00 -10.30
3 
miRNA  3' ugggauAUUCGUUAUAACGUGAu 5'
                |:|||:||  |||||| 
Target 5' ccggccTGAGCGAT-GTGCACTc 3'
 531 - 552 132.00 -18.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
573844 1 ClinVar
258124 2 ClinVar
1190282 54 ClinVar
1209510 54 ClinVar
1187339 176 ClinVar
COSN31527084 16 COSMIC
COSN31486614 17 COSMIC
COSN30467210 19 COSMIC
COSN30103452 26 COSMIC
COSN31486656 26 COSMIC
COSN30523202 32 COSMIC
COSN26976514 33 COSMIC
COSN19221423 72 COSMIC
COSN20104768 72 COSMIC
COSN20104766 76 COSMIC
COSN31552285 166 COSMIC
COSN31590434 167 COSMIC
COSN26561793 347 COSMIC
COSN24302222 359 COSMIC
COSN26687420 388 COSMIC
COSN31530364 430 COSMIC
COSN28750166 503 COSMIC
COSN31521376 543 COSMIC
COSN31569036 652 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs114713626 2 dbSNP
rs763569510 12 dbSNP
rs1369710862 14 dbSNP
rs764630195 15 dbSNP
rs774917764 20 dbSNP
rs762132714 23 dbSNP
rs1194808783 31 dbSNP
rs767890706 34 dbSNP
rs753462460 35 dbSNP
rs754574614 37 dbSNP
rs1170379881 38 dbSNP
rs1172119640 42 dbSNP
rs1467476071 42 dbSNP
rs754512395 42 dbSNP
rs981415192 42 dbSNP
rs28687249 45 dbSNP
rs1481044459 46 dbSNP
rs1270185913 50 dbSNP
rs779406686 51 dbSNP
rs757896616 52 dbSNP
rs777625829 53 dbSNP
rs113516962 54 dbSNP
rs1299118968 54 dbSNP
rs1385683285 54 dbSNP
rs145777348 54 dbSNP
rs1488207449 54 dbSNP
rs376321904 54 dbSNP
rs538213357 54 dbSNP
rs60473969 54 dbSNP
rs878893575 54 dbSNP
rs1440605235 58 dbSNP
rs28727967 58 dbSNP
rs1332839424 62 dbSNP
rs1444095438 63 dbSNP
rs1206750516 73 dbSNP
rs1399172289 73 dbSNP
rs1251901695 81 dbSNP
rs1466881943 93 dbSNP
rs553334489 97 dbSNP
rs28609612 98 dbSNP
rs144986537 99 dbSNP
rs760195956 102 dbSNP
rs867483871 103 dbSNP
rs1041084259 108 dbSNP
rs1362449241 114 dbSNP
rs901155928 121 dbSNP
rs1237805555 124 dbSNP
rs997465232 128 dbSNP
rs1029338667 131 dbSNP
rs1254132561 144 dbSNP
rs1479188801 155 dbSNP
rs543983970 160 dbSNP
rs1006014295 165 dbSNP
rs565280080 166 dbSNP
rs532614683 167 dbSNP
rs13308050 168 dbSNP
rs972212467 169 dbSNP
rs186844166 173 dbSNP
rs1404759777 174 dbSNP
rs559720811 175 dbSNP
rs1465964435 176 dbSNP
rs190543911 176 dbSNP
rs1381544014 177 dbSNP
rs370176726 180 dbSNP
rs1437918499 181 dbSNP
rs926868357 185 dbSNP
rs1188545244 187 dbSNP
rs13308085 190 dbSNP
rs1253794582 202 dbSNP
rs1199721991 203 dbSNP
rs989684930 204 dbSNP
rs3800585 215 dbSNP
rs945509129 227 dbSNP
rs538085901 232 dbSNP
rs1338391034 236 dbSNP
rs549926568 236 dbSNP
rs1049710835 237 dbSNP
rs1395812373 239 dbSNP
rs1274745131 244 dbSNP
rs1361667826 246 dbSNP
rs1340787130 264 dbSNP
rs1417894972 265 dbSNP
rs367991983 283 dbSNP
rs1269075113 284 dbSNP
rs571289905 291 dbSNP
rs1016081237 292 dbSNP
rs538742870 293 dbSNP
rs553557466 297 dbSNP
rs1265189813 298 dbSNP
rs887252541 302 dbSNP
rs1191462087 308 dbSNP
rs575979368 321 dbSNP
rs1487948536 323 dbSNP
rs1246486543 328 dbSNP
rs71581929 329 dbSNP
rs1291851642 332 dbSNP
rs571710297 334 dbSNP
rs1453121456 341 dbSNP
rs1353736683 345 dbSNP
rs1234422308 352 dbSNP
rs1258795853 356 dbSNP
rs1244457855 358 dbSNP
rs1341553799 360 dbSNP
rs1170968900 362 dbSNP
rs1390899943 365 dbSNP
rs1340510340 385 dbSNP
rs535805279 387 dbSNP
rs1166206222 388 dbSNP
rs183078755 390 dbSNP
rs1465913439 391 dbSNP
rs1425475538 395 dbSNP
rs746830787 397 dbSNP
rs1013775347 401 dbSNP
rs1025199253 406 dbSNP
rs768306795 412 dbSNP
rs1477450907 413 dbSNP
rs566549212 416 dbSNP
rs1387558223 420 dbSNP
rs1322652491 423 dbSNP
rs576323057 426 dbSNP
rs1266178896 431 dbSNP
rs1002499471 436 dbSNP
rs543680193 443 dbSNP
rs1437212698 444 dbSNP
rs1298196841 447 dbSNP
rs958308830 448 dbSNP
rs1317776921 453 dbSNP
rs1438646623 462 dbSNP
rs759459236 462 dbSNP
rs1329455003 474 dbSNP
rs14405 478 dbSNP
rs1445009597 484 dbSNP
rs1225616779 496 dbSNP
rs989839298 502 dbSNP
rs3188410 503 dbSNP
rs1063267 516 dbSNP
rs1208803373 524 dbSNP
rs1402807027 525 dbSNP
rs1328961597 532 dbSNP
rs1289635290 533 dbSNP
rs967154036 534 dbSNP
rs986602823 542 dbSNP
rs772624853 543 dbSNP
rs150932895 545 dbSNP
rs1178776488 547 dbSNP
rs187750413 548 dbSNP
rs932750616 564 dbSNP
rs1437638248 572 dbSNP
rs1279911028 584 dbSNP
rs1221408561 588 dbSNP
rs560924737 595 dbSNP
rs1343557622 597 dbSNP
rs1274326592 600 dbSNP
rs1240967719 603 dbSNP
rs1049752252 607 dbSNP
rs1329586529 608 dbSNP
rs909874633 613 dbSNP
rs942608069 614 dbSNP
rs1335989010 615 dbSNP
rs1412674926 618 dbSNP
rs559847791 620 dbSNP
rs919905697 621 dbSNP
rs1378050261 622 dbSNP
rs1191201553 623 dbSNP
rs1472948074 623 dbSNP
rs1238392504 625 dbSNP
rs931350057 628 dbSNP
rs1441119647 630 dbSNP
rs1047150024 632 dbSNP
rs1162836886 633 dbSNP
rs530161192 638 dbSNP
rs887199321 639 dbSNP
rs773502855 641 dbSNP
rs1320959495 645 dbSNP
rs1223411273 648 dbSNP
rs1380239525 649 dbSNP
rs1048458 650 dbSNP
rs1285728493 651 dbSNP
rs1364448464 656 dbSNP
rs558970516 657 dbSNP
rs1298758418 660 dbSNP
rs1048459 670 dbSNP
rs1420948357 676 dbSNP
rs1046598483 679 dbSNP
rs905393847 681 dbSNP
rs1002855640 687 dbSNP
rs1358042805 688 dbSNP
rs1157582856 690 dbSNP
rs1314256566 691 dbSNP
rs1032618440 707 dbSNP
rs957237821 708 dbSNP
rs117394163 718 dbSNP
rs1183901793 734 dbSNP
rs1019954959 737 dbSNP
rs1033372676 738 dbSNP
rs957672484 740 dbSNP
rs967101911 741 dbSNP
rs112798143 744 dbSNP
rs986550941 747 dbSNP
rs1269156847 748 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Flp-In T-REx 293-hAGO1 cells
Location of target site 3'UTR
Original Description (Extracted from the article) ... Validation of interactions identified by CLASH suppports their reliability. ...

- Helwak A; Kudla G; Dudnakova T; Tollervey D, 2013, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ugggauAUUCGUUAUAACGUGAu 5'
                |:|||:||  |||||| 
Target 5' ccggccTGAGCGAT-GTGCACTc 3'
 		5 - 26
Article - Helwak A; Kudla G; Dudnakova T; Tollervey D
- Cell, 2013
MicroRNAs (miRNAs) play key roles in gene regulation, but reliable bioinformatic or experimental identification of their targets remains difficult. To provide an unbiased view of human miRNA targets, we developed a technique for ligation and sequencing of miRNA-target RNA duplexes associated with human AGO1. Here, we report data sets of more than 18,000 high-confidence miRNA-mRNA interactions. The binding of most miRNAs includes the 5' seed region, but around 60% of seed interactions are noncanonical, containing bulged or mismatched nucleotides. Moreover, seed interactions are generally accompanied by specific, nonseed base pairing. 18% of miRNA-mRNA interactions involve the miRNA 3' end, with little evidence for 5' contacts, and some of these were functionally validated. Analyses of miRNA:mRNA base pairing showed that miRNA species systematically differ in their target RNA interactions, and strongly overrepresented motifs were found in the interaction sites of several miRNAs. We speculate that these affect the response of RISC to miRNA-target binding.
LinkOut: [PMID: 23622248]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE19536 Breast cancer -0.322 5.4e-4 -0.332 3.7e-4 100 Click to see details
GSE28544 Breast cancer -0.583 1.4e-3 -0.650 2.9e-4 24 Click to see details
GSE42095 Differentiated embryonic stem cells 0.575 2.1e-3 0.400 2.9e-2 23 Click to see details
GSE17498 Multiple myeloma -0.4 5.3e-3 -0.511 3.8e-4 40 Click to see details
GSE19783 ER- ER- breast cancer -0.286 5.3e-3 -0.346 8.9e-4 79 Click to see details
GSE27834 Pluripotent stem cells -0.443 4.3e-2 -0.524 1.9e-2 16 Click to see details
GSE14794 Lymphoblastoid cells 0.172 5.3e-2 0.149 8.1e-2 90 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.571 5.4e-2 0.600 4.4e-2 9 Click to see details
GSE35602 Colorectal cancer stromal tissue 0.287 8.2e-2 0.354 4.1e-2 25 Click to see details
GSE21687 Ependynoma primary tumors 0.165 9.6e-2 0.141 1.3e-1 64 Click to see details
GSE19783 ER+ ER+ breast cancer -0.295 1.0e-1 -0.400 4.0e-2 20 Click to see details
GSE26953 Aortic valvular endothelial cells -0.219 1.5e-1 -0.159 2.3e-1 24 Click to see details
GSE28260 Renal cortex and medulla 0.281 1.8e-1 0.253 2.0e-1 13 Click to see details
GSE17306 Multiple myeloma -0.135 1.8e-1 -0.117 2.1e-1 49 Click to see details
GSE19350 CNS germ cell tumors 0.287 1.8e-1 0.007 4.9e-1 12 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis -0.174 2.3e-1 -0.254 1.4e-1 20 Click to see details
GSE32688 Pancreatic cancer -0.024 4.5e-1 -0.037 4.2e-1 32 Click to see details
GSE38226 Liver fibrosis -0.026 4.6e-1 -0.118 3.1e-1 21 Click to see details
GSE21032 Prostate cancer 0.009 4.7e-1 -0.025 4.1e-1 83 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.013 4.8e-1 -0.123 2.8e-1 25 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.013 4.8e-1 -0.123 2.8e-1 25 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
STAD -0.648 0 -0.644 0 32 Click to see details
BLCA -0.682 0 -0.625 0 17 Click to see details
PRAD -0.227 0.06 -0.205 0.08 50 Click to see details
LUSC -0.242 0.07 -0.117 0.24 38 Click to see details
HNSC 0.21 0.09 0.230 0.07 42 Click to see details
LIHC 0.149 0.15 0.187 0.1 49 Click to see details
KICH 0.204 0.16 0.234 0.13 25 Click to see details
PAAD -0.649 0.18 -0.800 0.1 4 Click to see details
ESCA -0.31 0.18 -0.455 0.08 11 Click to see details
KIRC 0.105 0.2 0.058 0.32 68 Click to see details
THCA -0.109 0.21 -0.129 0.17 59 Click to see details
BRCA 0.06 0.3 -0.007 0.47 83 Click to see details
CHOL -0.186 0.32 -0.033 0.47 9 Click to see details
KIRP 0.086 0.32 0.016 0.47 32 Click to see details
UCEC -0.077 0.38 -0.163 0.25 19 Click to see details
CESC 0.335 0.39 0.500 0.33 3 Click to see details
PCPG 0.268 0.41 0.500 0.33 3 Click to see details
LUAD 0.04 0.45 0.308 0.17 12 Click to see details
LUAD 0.04 0.45 0.308 0.17 12 Click to see details
373 hsa-miR-454-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT007251 SMAD4 SMAD family member 4 5 8
MIRT039219 KCTD12 potassium channel tetramerization domain containing 12 1 1
MIRT039220 LRRC8D leucine rich repeat containing 8 VRAC subunit D 1 1
MIRT039221 ZBTB4 zinc finger and BTB domain containing 4 2 7
MIRT039222 SPTSSA serine palmitoyltransferase small subunit A 1 1
MIRT039223 PRKCSH protein kinase C substrate 80K-H 1 1
MIRT039224 METTL2A methyltransferase like 2A 1 1
MIRT039225 C6orf120 chromosome 6 open reading frame 120 1 1
MIRT039226 CSPP1 centrosome and spindle pole associated protein 1 1 1
MIRT039227 CHD7 chromodomain helicase DNA binding protein 7 1 1
MIRT039228 LTN1 listerin E3 ubiquitin protein ligase 1 1 1
MIRT039229 RAP2C RAP2C, member of RAS oncogene family 1 1
MIRT039230 RPL4 ribosomal protein L4 1 1
MIRT039231 POLR2A RNA polymerase II subunit A 1 1
MIRT039232 MRPL37 mitochondrial ribosomal protein L37 1 1
MIRT039233 BAHCC1 BAH domain and coiled-coil containing 1 1 1
MIRT039234 SIK3 SIK family kinase 3 1 1
MIRT039235 ZNF805 zinc finger protein 805 1 1
MIRT039236 TET1 tet methylcytosine dioxygenase 1 1 1
MIRT039237 HMGXB3 HMG-box containing 3 1 1
MIRT039238 POFUT2 protein O-fucosyltransferase 2 1 1
MIRT039239 PCSK6 proprotein convertase subtilisin/kexin type 6 1 1
MIRT039240 BHLHE40 basic helix-loop-helix family member e40 1 1
MIRT039241 MED12 mediator complex subunit 12 1 1
MIRT039242 FLNC filamin C 1 1
MIRT039243 STK38 serine/threonine kinase 38 1 1
MIRT039244 MRPS35 mitochondrial ribosomal protein S35 1 1
MIRT039245 TP53 tumor protein p53 1 1
MIRT039246 CNOT1 CCR4-NOT transcription complex subunit 1 1 1
MIRT039247 PPP1R7 protein phosphatase 1 regulatory subunit 7 1 1
MIRT039248 GID4 GID complex subunit 4 homolog 1 1
MIRT039249 PHF12 PHD finger protein 12 2 3
MIRT039250 UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 1 1
MIRT057500 CEP55 centrosomal protein 55 2 4
MIRT060511 PPP6R3 protein phosphatase 6 regulatory subunit 3 2 2
MIRT061519 OTUD3 OTU deubiquitinase 3 2 2
MIRT061804 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 10
MIRT062715 MLEC malectin 2 4
MIRT063602 FBXO28 F-box protein 28 2 2
MIRT064810 ZBTB18 zinc finger and BTB domain containing 18 2 2
MIRT065626 CLIC4 chloride intracellular channel 4 2 4
MIRT065898 RAB5B RAB5B, member RAS oncogene family 2 8
MIRT071011 SMOC1 SPARC related modular calcium binding 1 2 2
MIRT071920 ZFYVE9 zinc finger FYVE-type containing 9 2 2
MIRT075119 C16ORF70 chromosome 16 open reading frame 70 2 4
MIRT076031 COX10 COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor 2 6
MIRT079272 NPTX1 neuronal pentraxin 1 2 2
MIRT079362 CCDC137 coiled-coil domain containing 137 2 2
MIRT081131 LDLR low density lipoprotein receptor 2 6
MIRT083130 BTBD3 BTB domain containing 3 2 12
MIRT083156 SEC23B Sec23 homolog B, coat complex II component 2 4
MIRT086442 NABP1 nucleic acid binding protein 1 2 6
MIRT087868 CBY1 chibby family member 1, beta catenin antagonist 2 4
MIRT088348 MAPRE3 microtubule associated protein RP/EB family member 3 2 8
MIRT090809 MBNL1 muscleblind like splicing regulator 1 2 4
MIRT090904 ARHGEF26 Rho guanine nucleotide exchange factor 26 2 2
MIRT091219 USP13 ubiquitin specific peptidase 13 2 2
MIRT091700 TGFBR2 transforming growth factor beta receptor 2 2 6
MIRT092494 PTPRG protein tyrosine phosphatase, receptor type G 2 2
MIRT095388 UBE2D2 ubiquitin conjugating enzyme E2 D2 2 2
MIRT096901 ERBB2IP erbb2 interacting protein 2 2
MIRT097422 JMY junction mediating and regulatory protein, p53 cofactor 2 2
MIRT097465 PAPD4 poly(A) RNA polymerase D4, non-canonical 2 2
MIRT099324 QKI QKI, KH domain containing RNA binding 2 4
MIRT099841 SOX4 SRY-box 4 2 10
MIRT100782 ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 2 2
MIRT101821 PNRC1 proline rich nuclear receptor coactivator 1 2 2
MIRT102154 POP7 POP7 homolog, ribonuclease P/MRP subunit 2 4
MIRT102235 HBP1 HMG-box transcription factor 1 2 2
MIRT102624 UBN2 ubinuclein 2 2 8
MIRT105313 VPS37A VPS37A, ESCRT-I subunit 2 2
MIRT105436 ATP6V1B2 ATPase H+ transporting V1 subunit B2 2 10
MIRT105807 RAB11FIP1 RAB11 family interacting protein 1 2 2
MIRT107283 FAM73B mitoguardin 2 2 2
MIRT108268 HABP4 hyaluronan binding protein 4 2 4
MIRT108885 HPRT1 hypoxanthine phosphoribosyltransferase 1 2 2
MIRT109677 KLHL15 kelch like family member 15 2 6
MIRT109831 MID1IP1 MID1 interacting protein 1 2 8
MIRT123867 FZD6 frizzled class receptor 6 2 8
MIRT126574 MASTL microtubule associated serine/threonine kinase like 2 2
MIRT130148 TXNIP thioredoxin interacting protein 2 6
MIRT132502 DSTYK dual serine/threonine and tyrosine protein kinase 2 2
MIRT134787 CCND2 cyclin D2 2 2
MIRT139885 BTF3L4 basic transcription factor 3 like 4 2 6
MIRT142443 TNRC6A trinucleotide repeat containing 6A 2 6
MIRT154001 PRNP prion protein 2 2
MIRT162279 LMLN leishmanolysin like peptidase 2 4
MIRT164540 MSMO1 methylsterol monooxygenase 1 2 2
MIRT178076 SAMD8 sterile alpha motif domain containing 8 2 2
MIRT178935 C11ORF57 chromosome 11 open reading frame 57 2 2
MIRT179073 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 6
MIRT180851 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 4
MIRT182976 TROVE2 TROVE domain family member 2 2 2
MIRT193030 TMOD3 tropomodulin 3 2 8
MIRT195765 ATMIN ATM interactor 2 6
MIRT196627 TAOK1 TAO kinase 1 2 6
MIRT212153 CLCN3 chloride voltage-gated channel 3 2 4
MIRT217615 NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit 2 2
MIRT220701 MTPN myotrophin 2 4
MIRT222278 CCT6A chaperonin containing TCP1 subunit 6A 2 2
MIRT223641 ATP6V1C1 ATPase H+ transporting V1 subunit C1 2 4
MIRT224762 DPYSL2 dihydropyrimidinase like 2 2 2
MIRT227998 NFIB nuclear factor I B 2 4
MIRT230983 PRRG4 proline rich and Gla domain 4 2 2
MIRT242671 SALL3 spalt like transcription factor 3 2 4
MIRT243099 LCLAT1 lysocardiolipin acyltransferase 1 2 4
MIRT244079 EDN1 endothelin 1 2 2
MIRT246462 ZBTB7B zinc finger and BTB domain containing 7B 2 2
MIRT248079 SLC38A2 solute carrier family 38 member 2 2 4
MIRT270943 GPRC5A G protein-coupled receptor class C group 5 member A 2 2
MIRT295182 ZNF317 zinc finger protein 317 2 4
MIRT296535 STX16 syntaxin 16 2 2
MIRT301578 TNRC6B trinucleotide repeat containing 6B 2 2
MIRT316378 PPP1R14C protein phosphatase 1 regulatory inhibitor subunit 14C 2 2
MIRT323697 PLEKHF2 pleckstrin homology and FYVE domain containing 2 2 4
MIRT327914 CHIC1 cysteine rich hydrophobic domain 1 2 2
MIRT367113 ZNF711 zinc finger protein 711 2 4
MIRT368759 CDADC1 cytidine and dCMP deaminase domain containing 1 2 2
MIRT407342 IGFBP5 insulin like growth factor binding protein 5 2 2
MIRT448324 WNK3 WNK lysine deficient protein kinase 3 2 2
MIRT448957 CDK19 cyclin dependent kinase 19 2 4
MIRT449145 UQCRB ubiquinol-cytochrome c reductase binding protein 2 2
MIRT454117 MRPL52 mitochondrial ribosomal protein L52 2 2
MIRT459833 TPP1 tripeptidyl peptidase 1 2 2
MIRT460418 TNFRSF10B TNF receptor superfamily member 10b 2 4
MIRT461658 G6PC glucose-6-phosphatase catalytic subunit 2 2
MIRT462949 ZNF800 zinc finger protein 800 2 12
MIRT463646 YY1 YY1 transcription factor 2 8
MIRT464853 RPS27A ribosomal protein S27a 2 12
MIRT464873 UBB ubiquitin B 2 8
MIRT466321 THRA thyroid hormone receptor, alpha 2 2
MIRT466828 STX6 syntaxin 6 2 6
MIRT467415 SNTB1 syntrophin beta 1 2 4
MIRT467456 SNAPIN SNAP associated protein 2 2
MIRT468561 SERINC3 serine incorporator 3 2 10
MIRT469808 RAB14 RAB14, member RAS oncogene family 2 2
MIRT469869 PXK PX domain containing serine/threonine kinase like 2 8
MIRT470335 PPP6R1 protein phosphatase 6 regulatory subunit 1 2 2
MIRT473777 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 2
MIRT474740 KIF13A kinesin family member 13A 2 6
MIRT474957 KCTD10 potassium channel tetramerization domain containing 10 2 4
MIRT475482 HSPA8 heat shock protein family A (Hsp70) member 8 2 6
MIRT476297 GMFB glia maturation factor beta 2 10
MIRT477365 EOGT EGF domain specific O-linked N-acetylglucosamine transferase 2 4
MIRT477491 ELL2 elongation factor for RNA polymerase II 2 2 2
MIRT478112 DLG5 discs large MAGUK scaffold protein 5 2 6
MIRT479819 CCNA2 cyclin A2 2 6
MIRT480020 CAPRIN2 caprin family member 2 2 4
MIRT480841 BLCAP bladder cancer associated protein 2 10
MIRT481612 ARHGAP1 Rho GTPase activating protein 1 2 6
MIRT481871 ANKRD50 ankyrin repeat domain 50 2 2
MIRT484940 ZFYVE26 zinc finger FYVE-type containing 26 2 4
MIRT485124 SECISBP2L SECIS binding protein 2 like 2 4
MIRT485438 KLF6 Kruppel like factor 6 2 2
MIRT485572 FOXQ1 forkhead box Q1 2 2
MIRT485647 DICER1 dicer 1, ribonuclease III 2 8
MIRT486744 CNOT4 CCR4-NOT transcription complex subunit 4 2 6
MIRT490885 OSBP oxysterol binding protein 2 2
MIRT491424 PDZD11 PDZ domain containing 11 2 4
MIRT491646 PDRG1 p53 and DNA damage regulated 1 2 10
MIRT491792 ZNF24 zinc finger protein 24 2 2
MIRT492269 SIK1 salt inducible kinase 1 2 6
MIRT493093 MMGT1 membrane magnesium transporter 1 2 12
MIRT498068 SNX5 sorting nexin 5 2 6
MIRT498875 ZNF12 zinc finger protein 12 2 10
MIRT499895 KIAA1191 KIAA1191 2 4
MIRT500406 ZMAT3 zinc finger matrin-type 3 2 10
MIRT500732 TRIM37 tripartite motif containing 37 2 2
MIRT500921 STARD13 StAR related lipid transfer domain containing 13 2 4
MIRT501472 PTPN4 protein tyrosine phosphatase, non-receptor type 4 2 8
MIRT501552 POC1B-GALNT4 POC1B-GALNT4 readthrough 2 2
MIRT501785 NRBF2 nuclear receptor binding factor 2 2 6
MIRT501993 MAPK1 mitogen-activated protein kinase 1 2 10
MIRT502012 MAP7 microtubule associated protein 7 2 8
MIRT502417 GALNT4 polypeptide N-acetylgalactosaminyltransferase 4 2 2
MIRT502517 ESR1 estrogen receptor 1 2 2
MIRT502758 CLIP1 CAP-Gly domain containing linker protein 1 2 8
MIRT503052 CAMSAP2 calmodulin regulated spectrin associated protein family member 2 2 2
MIRT503473 ZNF154 zinc finger protein 154 2 6
MIRT503676 SLC46A1 solute carrier family 46 member 1 2 2
MIRT504270 PARP1 poly(ADP-ribose) polymerase 1 2 6
MIRT504554 ZNF417 zinc finger protein 417 2 6
MIRT504683 ATP6V0D1 ATPase H+ transporting V0 subunit d1 2 6
MIRT505250 UBE2D3 ubiquitin conjugating enzyme E2 D3 2 2
MIRT505876 POLR1B RNA polymerase I subunit B 2 4
MIRT506465 NACC2 NACC family member 2 2 4
MIRT506506 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 4
MIRT506690 LZIC leucine zipper and CTNNBIP1 domain containing 2 4
MIRT507905 CALM2 calmodulin 2 2 6
MIRT509659 ZNF354B zinc finger protein 354B 2 10
MIRT510724 SPG20 spartin 2 6
MIRT510863 RAN RAN, member RAS oncogene family 2 8
MIRT511092 NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 2 4
MIRT511247 KLHL36 kelch like family member 36 2 6
MIRT513212 RFT1 RFT1 homolog 2 2
MIRT513618 VPS37B VPS37B, ESCRT-I subunit 2 2
MIRT513716 RBM20 RNA binding motif protein 20 2 4
MIRT513910 GRB10 growth factor receptor bound protein 10 2 6
MIRT514366 UBBP4 ubiquitin B pseudogene 4 2 6
MIRT517865 NCAPD2 non-SMC condensin I complex subunit D2 2 4
MIRT521314 RRAGD Ras related GTP binding D 2 4
MIRT521697 PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 2 8
MIRT521771 PPIG peptidylprolyl isomerase G 2 8
MIRT524502 CEP170 centrosomal protein 170 2 4
MIRT527459 CLEC12B C-type lectin domain family 12 member B 2 2
MIRT530125 HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2 2
MIRT530844 RAG1 recombination activating 1 2 4
MIRT531099 PEX13 peroxisomal biogenesis factor 13 2 2
MIRT533490 TRIM71 tripartite motif containing 71 2 2
MIRT534267 SLC12A7 solute carrier family 12 member 7 2 2
MIRT534718 RFX7 regulatory factor X7 2 2
MIRT535265 PIGA phosphatidylinositol glycan anchor biosynthesis class A 2 4
MIRT536337 LEFTY1 left-right determination factor 1 2 2
MIRT536405 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT538270 CUL3 cullin 3 2 4
MIRT538411 COX20 COX20, cytochrome c oxidase assembly factor 2 2
MIRT539457 ADARB2 adenosine deaminase, RNA specific B2 (inactive) 2 2
MIRT540445 RBM43 RNA binding motif protein 43 2 2
MIRT541131 RAB34 RAB34, member RAS oncogene family 2 2
MIRT543568 RPF2 ribosome production factor 2 homolog 2 4
MIRT544105 IPMK inositol polyphosphate multikinase 2 2
MIRT544487 TRIM4 tripartite motif containing 4 2 2
MIRT544690 ZNF224 zinc finger protein 224 2 4
MIRT544986 MFF mitochondrial fission factor 2 4
MIRT546273 TMEM30A transmembrane protein 30A 2 4
MIRT546562 SATB2 SATB homeobox 2 2 2
MIRT546654 RPS6KA5 ribosomal protein S6 kinase A5 2 2
MIRT546774 RLIM ring finger protein, LIM domain interacting 2 2
MIRT546956 SFTPA1 surfactant protein A1 2 2
MIRT547040 POGZ pogo transposable element derived with ZNF domain 2 2
MIRT547494 MBNL3 muscleblind like splicing regulator 3 2 4
MIRT547911 HOXA5 homeobox A5 2 2
MIRT548401 ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 2 4
MIRT548479 EGLN3 egl-9 family hypoxia inducible factor 3 2 2
MIRT548645 DAPK1 death associated protein kinase 1 2 2
MIRT548852 CERCAM cerebral endothelial cell adhesion molecule 2 2
MIRT548889 CHEK2 checkpoint kinase 2 2 4
MIRT549138 BRWD1 bromodomain and WD repeat domain containing 1 2 4
MIRT549183 BMP3 bone morphogenetic protein 3 2 2
MIRT549335 ARHGAP12 Rho GTPase activating protein 12 2 4
MIRT549433 ACVR1 activin A receptor type 1 2 2
MIRT549463 ACSL4 acyl-CoA synthetase long chain family member 4 2 2
MIRT549491 ACBD5 acyl-CoA binding domain containing 5 2 2
MIRT550212 MAVS mitochondrial antiviral signaling protein 2 4
MIRT551702 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT552152 DAD1 defender against cell death 1 2 2
MIRT552358 ZNF620 zinc finger protein 620 2 2
MIRT552521 ZIC5 Zic family member 5 2 2
MIRT552848 WIPF2 WAS/WASL interacting protein family member 2 2 2
MIRT552885 WASL Wiskott-Aldrich syndrome like 2 4
MIRT553307 TSPAN3 tetraspanin 3 2 2
MIRT553347 TRPC3 transient receptor potential cation channel subfamily C member 3 5 4
MIRT553714 TCF7L2 transcription factor 7 like 2 2 2
MIRT553895 SUN2 Sad1 and UNC84 domain containing 2 2 4
MIRT554851 RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 2 2
MIRT555078 PURG purine rich element binding protein G 2 2
MIRT555198 PRUNE2 prune homolog 2 2 2
MIRT556193 MCC mutated in colorectal cancers 2 2
MIRT556224 MB21D2 Mab-21 domain containing 2 2 2
MIRT556482 LIPA lipase A, lysosomal acid type 2 2
MIRT556965 IER3IP1 immediate early response 3 interacting protein 1 2 2
MIRT557022 HOXD11 homeobox D11 2 2
MIRT557076 HOXB3 homeobox B3 2 2
MIRT557580 GNPTAB N-acetylglucosamine-1-phosphate transferase alpha and beta subunits 2 2
MIRT558280 DYNC1LI2 dynein cytoplasmic 1 light intermediate chain 2 2 2
MIRT558415 DEPDC1 DEP domain containing 1 2 2
MIRT558769 CFL2 cofilin 2 2 2
MIRT559632 AKIRIN2 akirin 2 2 2
MIRT560230 KLHL21 kelch like family member 21 2 4
MIRT560649 ZNF107 zinc finger protein 107 2 2
MIRT560931 CDK2AP2 cyclin dependent kinase 2 associated protein 2 2 2
MIRT563754 ZNF678 zinc finger protein 678 2 2
MIRT566007 RNF11 ring finger protein 11 2 2
MIRT566158 RACGAP1 Rac GTPase activating protein 1 2 2
MIRT566692 MYLIP myosin regulatory light chain interacting protein 2 2
MIRT567065 KCNB1 potassium voltage-gated channel subfamily B member 1 2 2
MIRT567532 FGFR1OP FGFR1 oncogene partner 2 2
MIRT567767 DLC1 DLC1 Rho GTPase activating protein 2 2
MIRT567831 DCUN1D3 defective in cullin neddylation 1 domain containing 3 2 2
MIRT571621 SRSF2 serine and arginine rich splicing factor 2 2 2
MIRT573076 ABCD2 ATP binding cassette subfamily D member 2 2 2
MIRT610908 NF2 neurofibromin 2 2 2
MIRT620056 ODF4 outer dense fiber of sperm tails 4 2 2
MIRT623177 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 2 2
MIRT627016 FIG4 FIG4 phosphoinositide 5-phosphatase 2 2
MIRT627082 SF3A1 splicing factor 3a subunit 1 2 2
MIRT628280 CYB5D1 cytochrome b5 domain containing 1 2 2
MIRT629099 F2RL1 F2R like trypsin receptor 1 2 2
MIRT629239 CINP cyclin dependent kinase 2 interacting protein 2 2
MIRT629415 ADM2 adrenomedullin 2 2 2
MIRT629590 RFC2 replication factor C subunit 2 2 2
MIRT629643 WDR31 WD repeat domain 31 2 2
MIRT629804 GPR82 G protein-coupled receptor 82 2 2
MIRT629878 NOM1 nucleolar protein with MIF4G domain 1 2 2
MIRT629922 POLR2D RNA polymerase II subunit D 2 2
MIRT629987 NARS asparaginyl-tRNA synthetase 2 2
MIRT630048 TERF2 telomeric repeat binding factor 2 2 2
MIRT630066 NIP7 NIP7, nucleolar pre-rRNA processing protein 2 2
MIRT630161 ZBTB8A zinc finger and BTB domain containing 8A 2 2
MIRT630256 SMTNL2 smoothelin like 2 2 2
MIRT630286 PSMB5 proteasome subunit beta 5 2 2
MIRT630350 NKAP NFKB activating protein 2 2
MIRT630500 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT632051 ATF7IP activating transcription factor 7 interacting protein 2 2
MIRT632476 RPS15A ribosomal protein S15a 2 2
MIRT632603 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT632999 DUSP18 dual specificity phosphatase 18 2 2
MIRT633086 CXorf21 chromosome X open reading frame 21 2 2
MIRT635056 MYH11 myosin heavy chain 11 2 2
MIRT635949 PLA2G12A phospholipase A2 group XIIA 2 2
MIRT636660 CDK4 cyclin dependent kinase 4 2 2
MIRT637191 ROMO1 reactive oxygen species modulator 1 2 2
MIRT637930 LILRA2 leukocyte immunoglobulin like receptor A2 2 2
MIRT641813 USP32 ubiquitin specific peptidase 32 2 2
MIRT642648 PTGR2 prostaglandin reductase 2 2 2
MIRT644240 SLC35E3 solute carrier family 35 member E3 2 2
MIRT644669 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT645097 SLC35E2B solute carrier family 35 member E2B 2 2
MIRT645997 ACP6 acid phosphatase 6, lysophosphatidic 2 2
MIRT646512 FAM217B family with sequence similarity 217 member B 2 2
MIRT646778 IL23R interleukin 23 receptor 2 2
MIRT648519 PIGG phosphatidylinositol glycan anchor biosynthesis class G 2 2
MIRT651469 XIAP X-linked inhibitor of apoptosis 2 2
MIRT654353 RBM27 RNA binding motif protein 27 2 2
MIRT660831 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT661183 S1PR2 sphingosine-1-phosphate receptor 2 2 2
MIRT661244 ARL17B ADP ribosylation factor like GTPase 17B 2 2
MIRT662847 OMD osteomodulin 2 2
MIRT662922 MED18 mediator complex subunit 18 2 2
MIRT663549 CCR6 C-C motif chemokine receptor 6 2 2
MIRT664360 C16orf45 chromosome 16 open reading frame 45 2 2
MIRT666085 SSTR2 somatostatin receptor 2 2 2
MIRT666261 SLC31A1 solute carrier family 31 member 1 2 2
MIRT666681 RBM23 RNA binding motif protein 23 2 2
MIRT667233 NFE2L1 nuclear factor, erythroid 2 like 1 2 2
MIRT667760 KDELR1 KDEL endoplasmic reticulum protein retention receptor 1 2 2
MIRT669264 C4orf36 chromosome 4 open reading frame 36 2 2
MIRT671480 FLYWCH2 FLYWCH family member 2 2 2
MIRT671502 SLC38A9 solute carrier family 38 member 9 2 2
MIRT671930 PLEKHS1 pleckstrin homology domain containing S1 2 4
MIRT672297 GP2 glycoprotein 2 2 2
MIRT672608 IRF1 interferon regulatory factor 1 2 2
MIRT674033 ANKRD9 ankyrin repeat domain 9 2 2
MIRT674225 FAM120AOS family with sequence similarity 120A opposite strand 2 2
MIRT674535 PRR23A proline rich 23A 2 2
MIRT675107 SNTB2 syntrophin beta 2 2 2
MIRT675273 ZNF431 zinc finger protein 431 2 2
MIRT684270 PRPF4 pre-mRNA processing factor 4 2 2
MIRT694280 ZNF529 zinc finger protein 529 2 4
MIRT698253 TMEM2 transmembrane protein 2 2 2
MIRT699912 RUNDC1 RUN domain containing 1 2 2
MIRT702594 JARID2 jumonji and AT-rich interaction domain containing 2 2 2
MIRT705199 BTG1 BTG anti-proliferation factor 1 2 2
MIRT706927 THAP6 THAP domain containing 6 2 2
MIRT708878 MOCS2 molybdenum cofactor synthesis 2 2 2
MIRT709115 C3orf18 chromosome 3 open reading frame 18 2 2
MIRT709615 KBTBD6 kelch repeat and BTB domain containing 6 2 2
MIRT710589 CDCA4 cell division cycle associated 4 2 2
MIRT710793 IFNLR1 interferon lambda receptor 1 2 2
MIRT711775 RFXAP regulatory factor X associated protein 2 2
MIRT713336 KLRD1 killer cell lectin like receptor D1 2 2
MIRT713633 MED8 mediator complex subunit 8 2 2
MIRT713907 IGF2R insulin like growth factor 2 receptor 2 2
MIRT715061 TMTC1 transmembrane and tetratricopeptide repeat containing 1 2 2
MIRT715178 DTX4 deltex E3 ubiquitin ligase 4 2 2
MIRT715196 FKTN fukutin 2 2
MIRT715272 RNF125 ring finger protein 125 2 2
MIRT717800 FAM114A1 family with sequence similarity 114 member A1 2 2
MIRT720536 CHERP calcium homeostasis endoplasmic reticulum protein 2 2
MIRT736758 TSPAN1 tetraspanin 1 4 0
MIRT736759 FAM83A family with sequence similarity 83 member A 4 0
MIRT736761 SBF2 SET binding factor 2 3 0
MIRT736853 FRZB frizzled-related protein 1 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-454 5-Fluorouracil approved 3385 Microarray MCF-7 breast cancer cells 21506117 2011 down-regulated
miR-454-3p 4-hydroxynonenal NULL 5283344 Microarray human leukemic HL-60 cell 19022373 2009 down-regulated
miR-454-3p Diethylstilbestrol approved 448537 Microarray mammosphere-derived epithelial cells (MDEC) 19549897 2009 down-regulated
miR-454-3p Formaldehyde NULL 712 Microarray Human lung epithelial cells (A549) 21147603 2011 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-454 Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-mir-454 Cisplatin 5460033 NSC119875 approved resistant cell line (W1)
hsa-mir-454 Tamoxifen 2733525 NSC180973 approved sensitive cell line (MCF7)
hsa-mir-454 Cisplatin 5460033 NSC119875 approved sensitive cell line (BxPC3)
hsa-miR-454-3p (1-(((2-amino-6-chloro-4-pyrimidinyl)amino)methyl)-3-(benzyloxy)cyclopentyl)methanol 385240 NSC676353 sensitive
hsa-miR-454-3p (1,1,3-trioxo-1,2-benzothiazol-2-yl)methyl 4-methylpiperazine-1-carbodithioate 16072473 NSC735181 sensitive
hsa-miR-454-3p (1r)-(-)-3-nitromethine-6-endo-acetoxycamphor 3004516 NSC657829 sensitive
hsa-miR-454-3p (2E)-2-[(4-chlorophenyl)methylidene]-5-(morpholin-4-ylmethyl)cyclopentan-1-one;hydrochloride 50988453 NSC639517 sensitive
hsa-miR-454-3p (2e)-5,6-dimethoxy-2-[(3-phenacyloxyphenyl)methylidene]-3h-inden-1-one 45028869 NSC744650 sensitive
hsa-miR-454-3p (3S,8R,9S,10R,13S,14S,16E,17S)-16-[[4-(3-imidazol-1-ylpropoxy)-3-methoxyphenyl]methylidene]-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,17-dodecahydrocyclopenta[a]phenanthrene-3,17-diol 24204037 NSC730478 resistant
hsa-miR-454-3p (3z,5z)-3,5-bis[(4-fluorophenyl)methylidene]-1,1-dimethylpiperidin-1-ium-4-one;iodide 54608810 NSC634794 sensitive
hsa-miR-454-3p (4-(1,3-dihydro-2h-pyrrolo[3,4-b]quinolin-2-ylcarbonyl)-2-oxotetrahydro-3-furanyl)methyl acetate 283490 NSC138333 sensitive
hsa-miR-454-3p (4E,5Z)-4,5-bis[(6-bromoquinazolin-4-yl)hydrazinylidene]pentane-1,2,3-triol 54611941 NSC716031 sensitive
hsa-miR-454-3p (4r)-4-[(1r,4z,8e,10z,12s,15r,17r)-5,12-dimethyl-3-oxo-17-(2-phenylethoxy)-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one 46239554 NSC751494 resistant
hsa-miR-454-3p (4s,8s,12s,16s)-4,8,12,16-tetrabenzyl-1,9-bis(prop-2-enyl)-1,5,9,13-tetrazacyclohexadecane-2,6,10,14-tetrone 403842 NSC719376 sensitive
hsa-miR-454-3p (4Z,9Z,14Z)-2,2,7,7,12,12,17,17-octamethyl-21-oxabicyclo[16.2.1]henicosa-1(20),4,9,14,18-pentaene-3,6,8,11,13,16-hexone 5387611 NSC625154 sensitive
hsa-miR-454-3p (5E)-2-[(dimethylamino)methyl]-5-heptylidenecyclopentan-1-one;hydrochloride 5387764 NSC626879 sensitive
hsa-miR-454-3p (5e)-2-[[5-methyl-4-[5-methyl-2-[[(5e)-5-[(4-methylphenyl)methylidene]-4-oxo-1,3-thiazol-2-yl]amino]-1,3-thiazol-4-yl]-1,3-thiazol-2-yl]amino]-5-[(4-methylphenyl)methylidene]-1,3-thiazol-4-one NSC730523 resistant
hsa-miR-454-3p (5E,6Z)-5,6-bis[(6,8-dibromoquinazolin-4-yl)hydrazinylidene]hexane-1,2,3,4-tetrol 54611942 NSC716034 sensitive
hsa-miR-454-3p (6Z)-6-[(2-methoxyphenyl)methylidene]-3-(3-nitrophenyl)-[1,3]thiazolo[2,3-b][1,3]thiazol-4-ium-5-one 5847653 NSC657446 sensitive
hsa-miR-454-3p (8e)-2-amino-4-(3,4-dimethoxyphenyl)-8-[(3,4-dimethoxyphenyl)methylidene]-5-methyl-6,7-dihydro-5h-quinoline-3-carbonitrile NSC690754 sensitive
hsa-miR-454-3p (8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-10,13-dimethyl-17-(2-phenyl-1,3-thiazol-4-yl)-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one 261360 NSC93354 sensitive
hsa-miR-454-3p (e)-3-(4-hydroxyphenyl)-1-[5-methyl-1-[8-(trifluoromethyl)quinolin-4-yl]triazol-4-yl]prop-2-en-1-one NSC736153 sensitive
hsa-miR-454-3p (E)-3-(4-phenylphenyl)-1-thiophen-2-ylprop-2-en-1-one 5782484 NSC700125 sensitive
hsa-miR-454-3p (e)-5-morpholin-4-yl-1,2-diphenylpent-1-en-3-one;hydrochloride 5386798 NSC617826 sensitive
hsa-miR-454-3p (e)-phenyl(2-pyridinyl)methanone (6-chloro-4-pyrimidinyl)hydrazone 9571636 NSC693248 sensitive
hsa-miR-454-3p (z)-1-(5-chloro-2-hydroxyphenyl)-3-quinolin-2-ylprop-2-en-1-one NSC71097 sensitive
hsa-miR-454-3p (z)-6-(2-(pyridin-2-ylmethylene)hydrazinyl)-9h-purine 60147744 NSC752329 sensitive
hsa-miR-454-3p [(1S,5Z,9S,10R)-12-oxo-11-azabicyclo[8.2.0]dodec-5-en-3,7-diyn-9-yl] acetate 5470109 NSC697685 sensitive
hsa-miR-454-3p [(2r,3s,4r,5r)-5-(6-chloropurin-9-yl)-4-hydroxy-2-(trityloxymethyl)oxolan-3-yl] benzoate 401669 NSC715399 sensitive
hsa-miR-454-3p [(3s,8r,10r,13s,17e)-10,13-dimethyl-17-(phenylcarbamoyloxyimino)-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] n-phenylcarbamate 9569960 NSC629229 sensitive
hsa-miR-454-3p [(3s,8r,9s,10r,13s,14s,16e)-16-(1-acetyloxy-2,2,2-trifluoroethylidene)-10,13-dimethyl-17-oxo-2,3,4,7,8,9,11,12,14,15-decahydro-1h-cyclopenta[a]phenanthren-3-yl] acetate 5351782 NSC45238 sensitive
hsa-miR-454-3p [(3S,8R,9S,10R,13S,14S,16E,17S)-17-acetyloxy-16-[[3-methoxy-4-(2-piperidin-1-ylethoxy)phenyl]methylidene]-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,17-dodecahydrocyclopenta[a]phenanthren-3-yl] acetate 24204032 NSC730473 resistant
hsa-miR-454-3p [(E)-1-chlorobutylideneamino] N-[4-(trifluoromethoxy)phenyl]carbamate 5466270 NSC682840 sensitive
hsa-miR-454-3p [(E)-1-chloropropylideneamino] N-[2-(trifluoromethoxy)phenyl]carbamate 5466266 NSC682836 sensitive
hsa-miR-454-3p [1-[[[2-amino-6-chloro-5-[(4-chlorophenyl)diazenyl]pyrimidin-4-yl]amino]methyl]-3-phenylmethoxycyclobutyl]methanol 385284 NSC676395 sensitive
hsa-miR-454-3p [1,1,1,3,3,3-hexafluoro-2-(quinolin-2-ylmethyl)propan-2-yl] acetate 379602 NSC664303 sensitive
hsa-miR-454-3p [2-[[5-(4-amino-2-oxopyrimidin-1-yl)-3-ethynyl-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-octadecoxypropyl] [5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl hydrogen phosphate 6712908 NSC719661 sensitive
hsa-miR-454-3p [4-amino-2-[(4-chlorophenyl)amino]thiazol-5-yl]-(2-thienyl)methanone 399019 NSC709440 resistant
hsa-miR-454-3p [6-[(E)-(carbamothioylhydrazinylidene)methyl]pyridin-3-yl] 2-phenoxyacetate 9555563 NSC185057 sensitive
hsa-miR-454-3p 1',3',9-trihydroxy-6'-methoxy-3-pentylspiro[6,7-dihydro-2h-cyclopenta[g]isoquinoline-8,2'-cyclopenta[b]naphthalene]-1,4',5',8',9'-pentone 135489797 NSC676769 sensitive
hsa-miR-454-3p 1-(3-chlorophenyl)-3-[(z)-1-(2-pyridyl)ethylideneamino]thiourea 5494177 NSC668335 sensitive
hsa-miR-454-3p 1-(4-chlorophenyl)-3-[(Z)-[phenyl(pyridin-2-yl)methylidene]amino]thiourea 5465916 NSC668325 sensitive
hsa-miR-454-3p 1-[(2S)-3-[[2,7-di(piperidin-1-yl)-2,3,4a,5,7,7a-hexahydrofuro[3,4-b][1,4]dioxin-3-yl]oxy]oxolan-2-yl]piperidine 253322 NSC76150 sensitive
hsa-miR-454-3p 1-[(E)-(5-hydroxypyridin-2-yl)methylideneamino]-3-pyridin-3-ylthiourea 135443616 NSC185065 sensitive
hsa-miR-454-3p 1-[(E)-[phenyl(pyridin-2-yl)methylidene]amino]-3-(2-pyridin-2-ylethyl)thiourea 9571616 NSC689531 sensitive
hsa-miR-454-3p 1-[(E)-1H-indol-3-ylmethylideneamino]-2-phenylguanidine;nitric acid 135439995 NSC644582 resistant
hsa-miR-454-3p 1-[(z)-(2-oxoindolin-3-ylidene)amino]-3-(2-pyridylmethyl)thiourea 3005083 NSC670961 sensitive
hsa-miR-454-3p 1-[[2-(4-chlorophenyl)-4-methylidene-5-oxooxolan-2-yl]methyl]-5-methylpyrimidine-2,4-dione 381501 NSC668257 sensitive
hsa-miR-454-3p 1-[2-(2-pyridyl)ethyl]-3-[(e)-2-pyridylmethyleneamino]thiourea 9571904 NSC670779 sensitive
hsa-miR-454-3p 1-[3-(3,4-dimethoxyphenyl)-2-(2,4-dinitrophenyl)-3,4-dihydropyrazol-5-yl]naphthalen-2-ol 390439 NSC687793 sensitive
hsa-miR-454-3p 1-[3-[1-(3-chlorophenyl)-3-(4-methoxyphenyl)pyrazol-4-yl]-5-phenyl-3,4-dihydropyrazol-2-yl]ethanone 155815904 NSC763582 resistant
hsa-miR-454-3p 1-butan-2-yl-3-[(E)-1-(1H-imidazo[4,5-b]pyridin-2-yl)ethylideneamino]thiourea 135440008 NSC674098 sensitive
hsa-miR-454-3p 1-cyclohexyl-3-[(e)-[phenyl(2-pyridyl)methylene]amino]thiourea 5871897 NSC689540 sensitive
hsa-miR-454-3p 11-[(E)-2-(dimethylamino)ethenyl]pyrido[2,3-b]acridine-5,12-dione 5468977 NSC680733 resistant
hsa-miR-454-3p 11-[2-(dimethylamino)ethyl]pyrido[2,3-b]acridine-5,12-dione 387193 NSC680734 resistant
hsa-miR-454-3p 12-ethyl-3-methyl-8-phenyl-2,4,5,9,10,12-hexazatetracyclo[11.4.0.02,6.07,11]heptadeca-1(17),3,5,7,10,13,15-heptaene 383802 NSC672305 sensitive
hsa-miR-454-3p 12-iminodaunorubicin hcl 72400 NSC254681 sensitive
hsa-miR-454-3p 15,18-dihydroxy-5,7-dimethyl-11-thia-2,5,7,9-tetrazapentacyclo[10.8.0.02,10.03,8.014,19]icosa-1(12),3(8),9,14,16,18-hexaene-4,6,13,20-tetrone 380627 NSC666302 sensitive
hsa-miR-454-3p 1h-benzo[a]carbazole-1,4(11h)-dione, 11-phenyl- 369537 NSC641394 sensitive
hsa-miR-454-3p 2',6'-dibromospiro[7,8-dihydro-6h-pyrido[2,3-g]quinoline-9,4'-cyclohexa-2,5-diene]-1',5,10-trione 383051 NSC671095 resistant
hsa-miR-454-3p 2-(1-anilino-4-methyl-5-phenylimidazol-2-yl)sulfanyl-n-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]acetamide 60148160 NSC753772 sensitive
hsa-miR-454-3p 2-(3-methylbutylsulfanyl)naphthalene-1,4-dione 315743 NSC241494 sensitive
hsa-miR-454-3p 2-(3,5-bis(chloromethyl)-4-methoxyphenyl)-4h-thiochromen-4-one 355507 NSC609259 sensitive
hsa-miR-454-3p 2-(4-((oxiran-2-yl)methoxy)styryl)-4,5-dihydrooxazole 24206038 NSC737757 sensitive
hsa-miR-454-3p 2-(5-bromo-6-formyl-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethyl nitrate 383812 NSC672424 sensitive
hsa-miR-454-3p 2-(hydroxymethyl)-8-methyl-8-azabicyclo[3.2.1]octan-3-one NSC715572 sensitive
hsa-miR-454-3p 2-[(dimethylamino)methyl]-1-(2-nitrophenyl)prop-2-en-1-one 411522 NSC34821 sensitive
hsa-miR-454-3p 2-[(dimethylamino)methyl]-1-(4-methoxyphenyl)prop-2-en-1-one;hydrochloride 353911 NSC603553 sensitive
hsa-miR-454-3p 2-[(dimethylamino)methyl]cyclopentan-1-one 244760 NSC621888 sensitive
hsa-miR-454-3p 2-[(z)-2-(4-chlorophenyl)ethenyl]-1-methylquinolin-1-ium iodide 54598850 NSC10520 resistant
hsa-miR-454-3p 2-[[(2-aminobenzoyl)oxy-dibutyl-stannyl]amino]benzoic acid 16684416 NSC628572 sensitive
hsa-miR-454-3p 2-[[4-(1h-benzimidazol-2-yl)phenyl]iminomethyl]phenol 402059 NSC715755 sensitive
hsa-miR-454-3p 2-[[4-(2-dimethylaminoethylcarbamoyl)acridin-9-yl]amino]-3-sulfanyl-propanoic acid 392357 NSC692641 sensitive
hsa-miR-454-3p 2-[2-[4-(3-chloro-1,4-dihydroxy-5,8-dioxonaphthalen-2-yl)piperazin-1-yl]ethoxy]ethyl acetate 378769 NSC661939 sensitive
hsa-miR-454-3p 2-[3-hydroxy-4-(acetylamino)phenyl]benzothiazole 395431 NSC699969 sensitive
hsa-miR-454-3p 2-benzoyl-N-[(Z)-[[4-[bis(2-cyanoethyl)amino]-2-methylphenyl]-[(4-nitrophenyl)diazenyl]methylidene]amino]-5-chlorobenzamide 135493917 NSC681967 sensitive
hsa-miR-454-3p 2-bromo-5,8-dihydroxy-3-methyl-1,4-naphthoquinone 378912 NSC662383 sensitive
hsa-miR-454-3p 2-hydroxy discorhabdin d 362391 NSC626161 sensitive
hsa-miR-454-3p 2-methoxy-5h-pyrido[3,2:4,5]pyrrolo[3,2-c]cinnoline 54613488 NSC749296 sensitive
hsa-miR-454-3p 2,2'(1h,1'h)-spirobi[s-indacen]-1-one, 4'-acetyl-3,3',5,5',6,6',7,7'-octahydro- 382664 NSC670312 sensitive
hsa-miR-454-3p 2,2-dibutyl-7-methyl-1,3,2-benzodioxastannin-4-one 16683125 NSC628560 sensitive
hsa-miR-454-3p 2,3,10,11-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-8-one 392605 NSC693145 sensitive
hsa-miR-454-3p 2,6-bis((2-aminophenyl)thio)benzonitrile NSC679800 sensitive
hsa-miR-454-3p 2,6-bis(4-morpholinylmethyl)cyclohexanone,dihydrochloride NSC38535 sensitive
hsa-miR-454-3p 2,6-bis(pyrrolidin-1-ylmethyl)cyclohexan-1-one;hydrochloride 380174 NSC665622 sensitive
hsa-miR-454-3p 2,6-bis[(dimethylamino)methyl]cyclohexan-1-one;hydrochloride 358899 NSC619042 sensitive
hsa-miR-454-3p 2,7-dicyanoxanthone 363841 NSC629107 resistant
hsa-miR-454-3p 2,9-bis(bromomethyl)-1,10-phenanthroline 353741 NSC602850 sensitive
hsa-miR-454-3p 20-[3-[2-aminoethyl-[3-(15,16-dimethoxy-11,19-dioxo-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaen-20-yl)propyl]amino]propyl]-15,16-dimethoxy-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8) 45027842 NSC727620 sensitive
hsa-miR-454-3p 3-(3,5-dimethoxyphenoxy)-2-phenyl-7-(trifluoromethyl)quinoxalin-5-amine 393436 NSC695323 sensitive
hsa-miR-454-3p 3-(4-nitrophenyl)-6-phenyl-cyclohex-4-ene-1,1,2,2-tetracarbonitrile 391620 NSC691106 sensitive
hsa-miR-454-3p 3-[(1Z)-1-(1-hydroxypyridin-2-ylidene)ethyl]imino-1,1-dimethylthiourea 44384025 NSC351078 sensitive
hsa-miR-454-3p 3-[(Z)-[phenyl(pyridin-2-yl)methylidene]amino]-1,1-bis(pyridin-2-ylmethyl)thiourea 5466413 NSC689533 sensitive
hsa-miR-454-3p 3-[[4-(3,4-dihydroxyphenyl)-1,3-thiazol-2-yl]iminomethyl]-4-hydroxychromen-2-one;hydrochloride 135403636 NSC659390 sensitive
hsa-miR-454-3p 3-bromoquinolin-8-ol 384167 NSC673458 sensitive
hsa-miR-454-3p 3-hydroxy-2-methyl-5-[(2R)-6-methylhept-5-en-2-yl]cyclohexa-2,5-diene-1,4-dione 178981 NSC697134 sensitive
hsa-miR-454-3p 4-(2-pyridinyl)-5h-1,2,3-dithiazole-5-thione 25181424 NSC741898 sensitive
hsa-miR-454-3p 4-(6-thioguanine)-7-nitro-2,1,3-benzoxadiazole 3246652 NSC348401 sensitive
hsa-miR-454-3p 4-(furo[3,2-c]quinolin-4-ylamino)-n-(2-piperazin-1-ylethyl)benzamide 24204688 NSC732492 resistant
hsa-miR-454-3p 4-[(4e)-4-[(4-chlorophenyl)methylidene]-5-oxo-2-phenylimidazol-1-yl]-3-sulfanylidene-2h-1,2,4-triazin-5-one 5471340 NSC710587 sensitive
hsa-miR-454-3p 4-[(6-sulfanylidene-3,7-dihydropurin-8-yl)diazenyl]benzenesulfonamide 3246283 NSC75140 sensitive
hsa-miR-454-3p 4-[3-(4-chlorophenyl)-5-(2,5-dimethoxyphenyl)pyrazol-1-yl]benzenesulfonamide 24204421 NSC731805 sensitive
hsa-miR-454-3p 4-hydroxy-3-[(E)-(4-phenyl-1,3-thiazol-2-yl)iminomethyl]chromen-2-one 135409113 NSC658343 sensitive
hsa-miR-454-3p 4-O-tert-butyl 1-O-propan-2-yl 2-[8-(hydroxymethyl)-12-methoxy-9-oxo-11H-indolizino[1,2-b]quinolin-7-yl]butanedioate 384499 NSC674347 sensitive
hsa-miR-454-3p 4,6-dimethyl-5-phenyl-2-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]pyrrolo[3,4-c]pyrrole-1,3-dione 401045 NSC713750 sensitive
hsa-miR-454-3p 4b-hydroxy-10,10-dimethoxy-9ah-indeno[1,2-a]inden-9-one 363252 NSC628000 sensitive
hsa-miR-454-3p 5-(1-adamantyl)-2-benzyloxy-1h-benzimidazole 394400 NSC697859 sensitive
hsa-miR-454-3p 5-(3,5-dimethoxybenzyl)-2-hydroxy-5h-benzo[b]carbazole-6,11-dione 404489 NSC720725 resistant
hsa-miR-454-3p 5-bromo-3h-triazolo[4,5-d]pyrimidin-7-ol 135440019 NSC680827 sensitive
hsa-miR-454-3p 5-chloro-N-[(E)-[phenyl(pyridin-2-yl)methylidene]amino]pyridin-2-amine 6519698 NSC693627 sensitive
hsa-miR-454-3p 5-chloro-n-[(e)-1-pyridin-2-ylethylideneamino]-1,3-benzothiazol-2-amine 9572096 NSC703111 sensitive
hsa-miR-454-3p 5-fluoro-n-[(e)-1-pyridin-2-ylethylideneamino]-1,3-benzothiazol-2-amine 9572046 NSC693634 sensitive
hsa-miR-454-3p 5-hp 135453292 NSC107392 sensitive
hsa-miR-454-3p 5-methyl-n-[(e)-1-pyridin-2-ylethylideneamino]-1,3-benzothiazol-2-amine 9572094 NSC703109 sensitive
hsa-miR-454-3p 5-nitro-n-[(e)-[phenyl(pyridin-2-yl)methylidene]amino]pyridin-2-amine 6519692 NSC693620 sensitive
hsa-miR-454-3p 5,6,11,12-tetramethyl-5,5a,6,11,11a,12-hexahydroquinoxalino[2,3-b]quinoxaline 365519 NSC633207 sensitive
hsa-miR-454-3p 5,7-bis(trifluoromethyl)-2,3-dihydro-[1,2]thiazolo[2,3-a]azepine 1,1-dioxide 354292 NSC605440 sensitive
hsa-miR-454-3p 6-(3-aminopropyl)-9-methoxyindeno[1,2-c]isoquinoline-5,11-dione;hydrochloride 17755854 NSC736988 sensitive
hsa-miR-454-3p 6h-purine-6-thione, 1,7-dihydro-, mercury complex (9ci) NSC68294 sensitive
hsa-miR-454-3p 7-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3h-thieno[3,4-d]pyrimidine-4-thione 3005067 NSC670036 sensitive
hsa-miR-454-3p 7-[4,5-bis(4-methylphenoxy)oxolan-2-yl]-6-chloropurine 389531 NSC685828 sensitive
hsa-miR-454-3p 7-chloro-5-hydroxy-2-methoxy-2,4-dimethyl-1H-benzo[e][1]benzofuran-6,9-dione 359534 NSC620517 sensitive
hsa-miR-454-3p 7-methoxy-11-methyl-1h-benzo[a]carbazole-1,4(11h)-dione 373631 NSC650351 sensitive
hsa-miR-454-3p 7,8-dichloro-10-[3-(dimethylamino)propyl]benzo[g]pteridine-2,4-dione;hydrochloride 24185927 NSC44684 sensitive
hsa-miR-454-3p 72i9a2i712 221812 NSC6883 sensitive
hsa-miR-454-3p 8-{[(3as)-2-methylhexahydro-1h-pyrrolo[1,2-c][1,3,2]diazaphosphol-1-yl]oxy}quinoline 402496 NSC716522 sensitive
hsa-miR-454-3p 8-fluoro-11-methyl-1h-benzo[a]carbazole-1,4(11h)-dione 381772 NSC668844 sensitive
hsa-miR-454-3p 8-phenyl-7,8,9,10-tetrahydropyrimido[4,5-c]isoquinoline-1,3-diamine 401168 NSC714364 resistant
hsa-miR-454-3p 8455ab 1549990 NSC24189 sensitive
hsa-miR-454-3p 9-((2-chloroethyl)thio)-2,7-dimethoxyacridine 395389 NSC699925 sensitive
hsa-miR-454-3p 9-(3-chloro-2-hydroxy-propyl)-1,3-dimethyl-purino[7,8-a]pyrimidine-2,4,8-trione 392199 NSC692332 sensitive
hsa-miR-454-3p 9-(4-sulfamoylanilino)-n-(4-sulfamoylphenyl)acridine-4-carboxamide 365396 NSC633016 sensitive
hsa-miR-454-3p 9-ethylsulfinyl-2,7-dimethoxy-acridine 395385 NSC699921 sensitive
hsa-miR-454-3p 9-tert-butyl-4-(4-methoxyphenyl)-16-methyl-4,20-diazapentacyclo[11.7.0.02,6.07,12.014,19]icosa-1(13),14(19),15,17-tetraene-3,5-dione 376302 NSC657017 resistant
hsa-miR-454-3p 9h-quino[4,3,2-de][1,10]phenanthrolin-9-one, 5-methoxy- 388732 NSC683785 resistant
hsa-miR-454-3p Ab01327238-02 6892730 NSC670969 sensitive
hsa-miR-454-3p Alatolid 5359051 NSC295426 sensitive
hsa-miR-454-3p Amonafide 50515 NSC308847 sensitive
hsa-miR-454-3p Antineoplastic-654379 NSC654379 sensitive
hsa-miR-454-3p Antineoplastic-690271 391308 NSC690271 sensitive
hsa-miR-454-3p Aspiculamycin hcl 5458423 NSC200692 resistant
hsa-miR-454-3p Azane;[4-[(dithiocarboxyamino)methyl]cyclohexyl]methylcarbamodithioic acid 54600120 NSC136468 sensitive
hsa-miR-454-3p Benzofurazan, 5-nitro-6-(1-piperidinyl)-, 1-oxide 313603 NSC228132 sensitive
hsa-miR-454-3p Bromocopper;(dipyridin-2-ylmethylideneamino)-[methylsulfanyl(sulfoniumylidene)methyl]azanide 4318826 NSC321206 sensitive
hsa-miR-454-3p Bromocopper;1,1-dimethyl-3-[(E)-1-pyridin-2-ylethylideneamino]thiourea 9578864 NSC635448 sensitive
hsa-miR-454-3p C18281 361185 NSC624114 resistant
hsa-miR-454-3p Camptothecin derivative 97226 NSC107124 sensitive
hsa-miR-454-3p Camptothecin derivative 97226 NSC107124 sensitive
hsa-miR-454-3p Camptothecin derivative 97226 NSC107124 sensitive
hsa-miR-454-3p Camptothecin derivative 97226 NSC107124 sensitive
hsa-miR-454-3p Camptothecin derivative 97226 NSC107124 sensitive
hsa-miR-454-3p Chlorobis(4-ethyltropolonato)bismuth(iii) NSC634368 sensitive
hsa-miR-454-3p Chlorocopper(1+); n-[(e)-1-(2-pyridyl)ethylideneamino]azepane-1-carbothioamide 9578866 NSC635450 sensitive
hsa-miR-454-3p Chlorocopper;1,1-dipropyl-3-[(E)-1-pyridin-2-ylethylideneamino]thiourea 9578865 NSC635449 sensitive
hsa-miR-454-3p Crotonosid 223996 NSC12161 sensitive
hsa-miR-454-3p Cryptophycin b 5468424 NSC670038 resistant
hsa-miR-454-3p Cyanocycline a 100158 NSC349644 sensitive
hsa-miR-454-3p Cyclohexanone, 2,6-bis(piperidinomethyl)- 236587 NSC39202 sensitive
hsa-miR-454-3p Deoxyartemisitene 6712468 NSC690035 sensitive
hsa-miR-454-3p Dianhydrogalactitol 31789 NSC132313 sensitive
hsa-miR-454-3p Diethyl (Z)-2-[3-(2-ethoxy-2-oxoethyl)-2,4-dioxopyrimidin-1-yl]but-2-enedioate 5468905 NSC679002 sensitive
hsa-miR-454-3p Diethyl 2-[[4-[[6-(trifluoromethyl)quinoxalin-2-yl]amino]benzoyl]amino]pentanedioate 384948 NSC675772 resistant
hsa-miR-454-3p Dimethyl 5-benzoyl-1-[(Z)-2-[(Z)-1,4-dimethoxy-1,4-dioxobut-2-en-2-yl]sulfanyl-1-phenylethenyl]-2,3-dihydropyrrolo[1,2-a]imidazole-6,7-dicarboxylate 5468047 NSC663245 sensitive
hsa-miR-454-3p Enhydrin a 5359029 NSC294601 sensitive
hsa-miR-454-3p Ethanone, 1-(2-pyrimidinyl)-, (2-benzoxazolyl)hydrazone 9572051 NSC693639 sensitive
hsa-miR-454-3p Ethyl (E)-3-[(1S,3R)-2-(4-chlorobenzoyl)-3-[(E)-1,3-diethoxy-3-oxoprop-1-enyl]cyclopropyl]-3-ethoxyprop-2-enoate 5469838 NSC693207 sensitive
hsa-miR-454-3p Ethyl 3-[[5-[(e)-3-methoxy-3-oxoprop-1-enyl]-1h-imidazol-4-yl]diazenyl]benzoate 135436270 NSC716679 sensitive
hsa-miR-454-3p Ethyl 4-(5-cyano-2-methyl-1-phenyl-6-thioxo-pyrimidin-4-yl)piperazine-1-carboxylate 388267 NSC682881 sensitive
hsa-miR-454-3p Ethyl 5-amino-4-(3,4-dihydro-2h-1,5-benzodioxepin-7-ylamino)-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxylate 399955 NSC711107 sensitive
hsa-miR-454-3p Ethyl 7-(3,4-difluorophenyl)-10-methylsulfanyl-2-thia-5,7,9,11-tetrazatricyclo[6.3.1.04,12]dodeca-1(11),3,8(12),9-tetraene-3-carboxylate 399952 NSC711104 resistant
hsa-miR-454-3p Ethyl 7-(3,4-dihydro-2h-1,5-benzodioxepin-7-yl)-10-methylsulfanyl-2-thia-5,7,9,11-tetrazatricyclo[6.3.1.04,12]dodeca-1(11),3,8(12),9-tetraene-3-carboxylate 399951 NSC711103 resistant
hsa-miR-454-3p Ethyl 8-(4-chlorophenyl)-4-methyl-2-oxo-6-thiophen-2-yl-4a,7-dihydrochromene-3-carboxylate 392311 NSC692587 sensitive
hsa-miR-454-3p Fastigilin c 261577 NSC176507 sensitive
hsa-miR-454-3p Gw814408x 9604912 NSC756377 resistant
hsa-miR-454-3p Haterumalide na methyl esters 24204452 NSC731928 resistant
hsa-miR-454-3p Herbimycin 6436247 NSC305978 sensitive
hsa-miR-454-3p Idebenone 12881464 NSC759228 approved sensitive
hsa-miR-454-3p Incomptina b 5459288 NSC685707 sensitive
hsa-miR-454-3p Indenoisoquinoline derivative 329826 NSC314622 sensitive
hsa-miR-454-3p Inosine dialdehyde 135400916 NSC118994 sensitive
hsa-miR-454-3p Kinamycin c NSC138425 sensitive
hsa-miR-454-3p Kkiqvsbzfbkasx-uhfffaoysa-n 381513 NSC668269 sensitive
hsa-miR-454-3p Laurusin 135476719 NSC106486 sensitive
hsa-miR-454-3p Ls-144122 135408600 NSC52427 sensitive
hsa-miR-454-3p Ls-28225 16683189 NSC643845 sensitive
hsa-miR-454-3p Maxima isoflavone d 343081 NSC382028 resistant
hsa-miR-454-3p Methyl (2e)-2-[[3-(furan-2-carbonyl)-2-sulfanylideneimidazolidin-1-yl]methylidene]-3-oxobutanoate 24203795 NSC729527 resistant
hsa-miR-454-3p Methyl 4-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzoate 390508 NSC687945 sensitive
hsa-miR-454-3p Methyl 5-methyl-2-[(e)-(7-methyl-1-oxo-indan-2-ylidene)methyl]benzoate 6284987 NSC678362 sensitive
hsa-miR-454-3p Methyl N-[(E)-1-pyridin-2-ylethylideneamino]carbamodithioate 5947235 NSC251190 sensitive
hsa-miR-454-3p Methyl(2r,3as)-2-[(4-hydroxyphenyl)methyl]-1,3,3a,4-tetrahydropyrazolo[1,5-a]indole-2-carboxylate 398179 NSC707774 sensitive
hsa-miR-454-3p N'-((6-methyl-2-pyridinyl)methylene)-1-azepanecarbothiohydrazide 9554750 NSC667876 sensitive
hsa-miR-454-3p N'-(cyano(2-hydroxyphenyl)methyl)-2-phenylacetohydrazide 374997 NSC653823 sensitive
hsa-miR-454-3p N',N'-diethyl-N-(7-nitro-1,4-dioxido-1,2,4-benzotriazine-1,4-diium-3-yl)ethane-1,2-diamine 135426847 NSC628917 sensitive
hsa-miR-454-3p N',N'-diethyl-N-(7-nitro-1,4-dioxido-1,2,4-benzotriazine-1,4-diium-3-yl)ethane-1,2-diamine;hydrochloride 135488943 NSC628918 sensitive
hsa-miR-454-3p N-((3-benzoyl-2-thioxo-1-imidazolidinyl)carbothioyl)-n-phenylbenzamide 396960 NSC704180 sensitive
hsa-miR-454-3p N-(dipyridin-2-ylmethylideneamino)-1,3-benzoxazol-2-amine 404079 NSC720200 sensitive
hsa-miR-454-3p N-[(e)-(2-phenyl-1-pyridin-2-ylethylidene)amino]-1h-benzimidazol-2-amine NSC720194 sensitive
hsa-miR-454-3p N-[(e)-[(4-methoxyphenyl)-pyridin-2-ylmethylidene]amino]pyridin-2-amine 9630043 NSC693622 sensitive
hsa-miR-454-3p N-[(e)-[3-(dimethylamino)-1-phenylpropylidene]amino]aniline;hydrochloride 9569913 NSC625220 sensitive
hsa-miR-454-3p N-[(E)-[phenyl(pyridin-2-yl)methylidene]amino]pyridin-2-amine;zinc 9578819 NSC625544 sensitive
hsa-miR-454-3p N-[(E)-1-(6-methylpyridin-2-yl)ethylideneamino]-4-pyridin-2-ylpiperazine-1-carbothioamide 9554702 NSC335787 sensitive
hsa-miR-454-3p N-[(e)-1-isoquinolin-3-ylethylideneamino]-1-methylbenzimidazol-2-amine 9572093 NSC703108 sensitive
hsa-miR-454-3p N-[(e)-1-pyridin-2-ylethylideneamino]-[1,3]thiazolo[5,4-b]pyridin-2-amine 9572047 NSC693635 sensitive
hsa-miR-454-3p N-[(e)-1-pyridin-2-ylethylideneamino]-5-(trifluoromethyl)-1,3-benzothiazol-2-amine 9572095 NSC703110 sensitive
hsa-miR-454-3p N-[(e)-1-pyrimidin-2-ylethylideneamino]-1,3-benzothiazol-2-amine 9572048 NSC693636 sensitive
hsa-miR-454-3p N-[(E)-1-pyrimidin-4-ylethylideneamino]-1,3-benzothiazol-2-amine 5351439 NSC693632 sensitive
hsa-miR-454-3p N-[(Z)-[phenyl(pyridin-2-yl)methylidene]amino]piperidine-1-carbothioamide 5494336 NSC668300 sensitive
hsa-miR-454-3p N-[(z)-[phenyl(pyridin-2-yl)methylidene]amino]quinoxalin-2-amine 5869744 NSC693626 sensitive
hsa-miR-454-3p N-[2-(dimethylamino)ethyl]-9-nitrodibenzo-p-dioxin-1-carboxamide;hydrochloride 370721 NSC644221 sensitive
hsa-miR-454-3p N-[2-[6-amino-3-(chloromethyl)-2,3-dihydroindole-1-carbonyl]-1H-indol-5-yl]-1-benzofuran-2-carboxamide 394235 NSC697539 sensitive
hsa-miR-454-3p N-[2-acetamido-6-[[(2r,3s)-2-(dibenzylamino)-3-hydroxyhexyl]amino]pyrimidin-4-yl]acetamide 396448 NSC702421 sensitive
hsa-miR-454-3p N-[4-[(2-methoxy-11-oxo-6a,7,8,9-tetrahydropyrrolo[2,1-c][1,4]benzodiazepin-3-yl)oxy]butyl]-1h-indole-2-carboxamide 20826874 NSC726365 sensitive
hsa-miR-454-3p N-[5-[(e)-3-[8-(chloromethyl)-1-methyl-4-phenylmethoxy-7,8-dihydro-3h-pyrrolo[3,2-e]indol-6-yl]-3-oxoprop-1-enyl]-1-methylpyrrol-3-yl]butanamide 5469857 NSC693563 sensitive
hsa-miR-454-3p N~2~,n~4~-di(1-adamantyl)-6-chloro-1,3,5-triazine-2,4-diamine 394865 NSC698954 sensitive
hsa-miR-454-3p Neuro_000327 16683203 NSC643859 sensitive
hsa-miR-454-3p None 12201866 NSC179207 sensitive
hsa-miR-454-3p NSC294526 NSC294526 sensitive
hsa-miR-454-3p NSC374998 NSC374998 sensitive
hsa-miR-454-3p NSC605607 NSC605607 sensitive
hsa-miR-454-3p NSC664558 NSC664558 sensitive
hsa-miR-454-3p NSC688995 NSC688995 resistant
hsa-miR-454-3p NSC716032 NSC716032 sensitive
hsa-miR-454-3p NSC751830 NSC751830 resistant
hsa-miR-454-3p NSC762149 NSC762149 resistant
hsa-miR-454-3p O-aminoazotoluene 7340 NSC1797 sensitive
hsa-miR-454-3p Pada 81528 NSC9358 sensitive
hsa-miR-454-3p Pectenotoxin ii 5468320 NSC668555 resistant
hsa-miR-454-3p Pirarubicin hcl 11970024 NSC654509 sensitive
hsa-miR-454-3p Pmp (van) 72508 NSC1906 sensitive
hsa-miR-454-3p Razoxane 30623 NSC129943 sensitive
hsa-miR-454-3p S-[2-(2,6-dichlorophenyl)-3-oxoinden-1-yl] N,N-dimethylcarbamothioate 333069 NSC332837 sensitive
hsa-miR-454-3p Salarin c 24867082 NSC750154 resistant
hsa-miR-454-3p Selendale 54601159 NSC347466 resistant
hsa-miR-454-3p Stk849915 NSC691081 sensitive
hsa-miR-454-3p Stl434863 394348 NSC697730 sensitive
hsa-miR-454-3p Tert-butyl 2,6-dioxo-4-[1,2,3,4-tetrakis(phenylmethoxy)butyl]piperidine-3-carboxylate 386078 NSC677666 sensitive
hsa-miR-454-3p Tert-butyl 4-[(3,6-dioxocyclohexa-1,4-dien-1-yl)methylamino]benzoate 386493 NSC678637 sensitive
hsa-miR-454-3p Tetraplatin 13920603 NSC363812 sensitive
hsa-miR-454-3p Thiosemicarbazone r NSC319725 sensitive
hsa-miR-454-3p Thujaplicin mixture 252101 NSC73300 sensitive
hsa-miR-454-3p Trans-bis(acetato)amminepyridineplatinum(ii) NSC722781 sensitive
hsa-miR-454-3p Trimethyl-[(1-oxo-3,4-dihydro-2H-naphthalen-2-yl)methyl]azanium;iodide 375929 NSC656280 sensitive
hsa-miR-454-3p Trimethyl-[[2-oxo-3-[(trimethylazaniumyl)methyl]cyclohexyl]methyl]azanium;iodide 360569 NSC622700 sensitive
hsa-miR-454-3p Veracoquinazole 135416663 NSC601852 sensitive
hsa-miR-454-3p Vorinostat 5311 NSC701852 approved sensitive
hsa-miR-454-3p Z1603789400 236065 NSC38090 sensitive
hsa-miR-454-3p Z734296158 391673 NSC691215 sensitive
hsa-miR-454-3p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-454-3p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-454-3p Vincristine 5978 approved sensitive High Lymphoblastic Leukemia tissue
hsa-miR-454-3p Daunorubicin 30323 NSC82151 approved sensitive High Lymphoblastic Leukemia tissue
hsa-miR-454-3p L-Asparaginase sensitive High Lymphoblastic Leukemia tissue
hsa-miR-454-3p Prednisolone 5755 NSC9120 approved sensitive High Lymphoblastic Leukemia tissue
hsa-miR-454-3p Docetaxel 148124 NSC628503 approved resistant High Prostate Cancer cell line (PC-3)
hsa-miR-454-3p Fluorouracil 3385 NSC19893 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-454-3p Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-454-3p Sunitinib 5329102 NSC750690 approved resistant High Renal Cell Cancer tissue
hsa-miR-454-3p Cisplatin 5460033 NSC119875 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-454-3p Mitoxantrone 4212 NSC279836 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-454-3p Doxorubicin 31703 NSC123127 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-454-3p Curcumin 969516 NSC32982 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-454-3p Daunorubicin 30323 NSC82151 approved resistant High Acute Promyelocytic Leukemia cell line (HL60)
hsa-miR-454-3p Temozolomide 5394 NSC362856 approved resistant High Glioma tissue
hsa-miR-454-3p Platinum 23939 resistant High High-Grade Serous Ovarian Cancer tissue
hsa-miR-454-3p Cisplatin 5460033 NSC119875 approved sensitive Low Ovarian Cancer cell line (A2780, SKOV3)
hsa-miR-454-3p Sorafenib 216239 NSC747971 approved resistant Low Hepatocellular Carcinoma tissue
hsa-miR-454-3p Sorafenib 216239 NSC747971 approved resistant High Hepatocellular Carcinoma cell line (Huh-7)
hsa-miR-454-3p Cisplatin 5460033 NSC119875 approved sensitive Low Nasopharyngeal Cancer cell line (5-8F, SUNE-1)
hsa-miR-454-3p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (IGROV-1, W1)
hsa-miR-454-3p Cisplatin 5460033 NSC119875 approved resistant High Hypopharyngeal Cancer cell line (FaDu)
hsa-miR-454-3p Temozolomide 5394 NSC362856 approved sensitive cell line (U251)
hsa-miR-454-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-454-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-miR-454-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (HeyA8)
hsa-miR-454-3p Paclitaxel 36314 NSC125973 approved resistant cell line (SKVO3ip1)
hsa-miR-454-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM36)
hsa-miR-454-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM43)
hsa-miR-454-3p Exemestane 60198 NSC713563 approved resistant cell line (MCF-7)
hsa-miR-454-3p Testosterone+Anastrozole resistant cell line (MCF-7)
hsa-miR-454-3p Testosterone+Exemestane resistant cell line (MCF-7)
hsa-miR-454-3p Testosterone+Tamoxifen resistant cell line (MCF-7)
hsa-miR-454-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-454-3p Fluorouracil 3385 NSC19893 approved sensitive cell line (HCT15)
hsa-miR-454-3p Cisplatin 5460033 NSC119875 approved resistant cell line (MGC-803)
hsa-miR-454-3p 4-Hydroxytamoxifen+Tamoxifen sensitive cell line (LY2)
hsa-miR-454-3p Ethanol+Tamoxifen sensitive cell line (LY2)
hsa-miR-454-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-miR-454-3p Oxaliplatin 6857599 NSC266046 approved resistant cell line (IGROV-1)
hsa-miR-454-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-454-3p Neoadjuvant chemotherapy resistant tissue (breast cancer)
hsa-miR-454-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-454-3p Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)
hsa-miR-454-3p Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)
hsa-miR-454-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (H460)
hsa-miR-454-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-454-3p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide/Methotrexate/Gemcitabine resistant cell line (Bats-72)

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