miRTarBase - #MIRT040479


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pre-miRNA Information
pre-miRNA hsa-mir-605   
Genomic Coordinates chr10: 51299573 - 51299655
Synonyms MIRN605, hsa-mir-605, MIR605
Description Homo sapiens miR-605 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-605-5p
Sequence 16| UAAAUCCCAUGGUGCCUUCUCCU |38
Evidence Experimental
Experiments SAGE
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 3 10 + 51299590 29233923, 28550310 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs113212828 2 dbSNP
rs1265154909 7 dbSNP
rs76759855 9 dbSNP
rs1032735304 10 dbSNP
rs1318073696 10 dbSNP
rs1486056689 11 dbSNP
rs1225930966 12 dbSNP
rs1011066926 14 dbSNP
rs1261327694 19 dbSNP
rs1020985018 22 dbSNP
rs1426923077 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TRAF4   
Synonyms CART1, MLN62, RNF83
Description TNF receptor associated factor 4
Transcript NM_004295   
Expression
Putative miRNA Targets on TRAF4
3'UTR of TRAF4
(miRNA target sites are highlighted)		 
>TRAF4|NM_004295|3'UTR
   1 GTGCAGGTGGGGTTCGAGGGGAAAGGACGATGGGGCATGACCTCAGTCAGGCACTGGCTGAACTTGGAGAGGGGGCCGGA
  81 CCCCCGTCAGCTGCTTCTGCTGCCTAGGTTCTGTTACCCCATCCTCCCTCCCCCAGCCACCACCCTCAGGTGCCTCCAAT
 161 TGGTGCTTCAGCCCTGGCCCCTGTGGGGAACAGGTCTTGGGGTCATGAAGGGCTGGAAACAAGTGACCCCAGGGCCTGTC
 241 TCCCTTCTTGGGTAGGGCAGACATGCCTTGGTGCCGGTCACACTCTACACGGACTGAGGTGCCTGCTCAGGTGCTATGTC
 321 CCAAGAGCCATAAGGGGGTGGGAATTGGGGAGGGAGAAAGGGTAGTTCAAAGAGTCTGTCTTGAGATCTGATTTTTTCCC
 401 CCTTTACCTAGCTGTGCCCCCTCTGGTTATTTATTTCCTTAGTGCCAGGAGGGCACAGCAGGGGAGCCCTGATTTTTAAT
 481 AAATCCGGAATTGTATTTATTAATTTGCTTCCAGCCTGACTTACCTGGGTTGGTTAGGTCCCTGGGAGGCTCAACCAAAC
 561 TGAAGGCAAAGAAAGGACCAGTCAGAGAAGGGCCGCTGCCTGGGTCTGGCCCCAGGATCCAGCTTACCTGCTGGCTCGCC
 641 CTCTGATGGACGCCGGGAAAACTGCATCGGGCTTTGTGTGGAAGACGGTCCCTGCCACTGCCCTCTGCCGATGAAATGCG
 721 GGAAGTGTATGGCCTAGATGTTTCATAAGGCTGGAGTCCCTGGTCAGCCCCACCAGATTAGTGCTTCTACCCTAGGCAGG
 801 GCTTTCTTGGTCTAATGGTAATAAGCACCGACACTGCTAAGCACTTTACGTGCATTATTATTTCATTGAAAAGAACTGTC
 881 AAGTGAAATACTTTTTAGCACAGTAACTGGCTTTGTGGGCTCTAGAGAAGAGTTAATGAGGCAGTGCATGTTCTTGGCCC
 961 AGAGTAAGTGCTTAGTGAATGCTTTCTAACTCCGAACCCCAGCCACATCCAGGGACTGGGTGTTGAGCAAAAGGGGCCTT
1041 CAAGATGTTCAAGGCACTTGGATTTTCTCCTGTCTCTCATCGGCTTTTCTTAACGGGCCTCAGTGGGTGCATGTGATTAT
1121 CCACGTTTCACCTATGAAACATGAACAGAGGAGACTGACTTATCAGTGATTCTTCCGCGGGTTCGGACAGGGCCTCGATT
1201 CTGTTTTAAACTCCAGTAGTCCCTAGAAATTGTAGCTCCCTCTAGTTGTGGCAATAGGTGTGGGTCCTTGTGCTTGCTTT
1281 TGGCAAGTTTCTGAGCTACACAGGGCCTCCATTACCGTCACTGGTGAAATGCGGCTCACCTCCCAGATTTGTTGTAAAGA
1361 TTAAATGAACTGGTCAGCACA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uccucUUCCGUGGUACCCUAAAu 5'
               |||||||  | |||||| 
Target 5' tgttcAAGGCAC--TTGGATTTt 3'
 1046 - 1066 138.00 -15.40
2 
miRNA  3' ucCUCUUCCGUGGUA-CCCUAAAu 5'
            |:|||  |  ||| ||| ||| 
Target 5' ccGGGAAAACTGCATCGGGCTTTg 3'
 653 - 676 129.00 -11.40
3 
miRNA  3' uccUCUUCCGUGGUACCCUAAAu 5'
             | |||| :  :||||| || 
Target 5' gccATAAGGGG--GTGGGAATTg 3'
 327 - 347 124.00 -11.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30147476 12 COSMIC
COSN31495336 21 COSMIC
COSN30649238 32 COSMIC
COSN21473572 76 COSMIC
COSN21561909 87 COSMIC
COSN5178660 172 COSMIC
COSN31780653 182 COSMIC
COSN25320940 274 COSMIC
COSN26637175 274 COSMIC
COSN28165087 297 COSMIC
COSN30086527 315 COSMIC
COSN16128468 351 COSMIC
COSN26962282 375 COSMIC
COSN25425322 556 COSMIC
COSN5415174 566 COSMIC
COSN8674354 730 COSMIC
COSN28078552 773 COSMIC
COSN20113741 1094 COSMIC
COSN21205277 1250 COSMIC
rs3181215 737 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs561636944 4 dbSNP
rs763865696 5 dbSNP
rs1182592043 11 dbSNP
rs367932681 16 dbSNP
rs371664470 17 dbSNP
rs1214610584 19 dbSNP
rs1193530395 20 dbSNP
rs1480279990 21 dbSNP
rs781437530 29 dbSNP
rs35760160 30 dbSNP
rs755843596 37 dbSNP
rs756872921 44 dbSNP
rs779937752 45 dbSNP
rs780332977 46 dbSNP
rs1163758221 49 dbSNP
rs1032981083 61 dbSNP
rs559615823 63 dbSNP
rs1356996474 64 dbSNP
rs1434120601 64 dbSNP
rs1245495794 66 dbSNP
rs1341190359 71 dbSNP
rs1314982675 76 dbSNP
rs1389697691 77 dbSNP
rs892468007 78 dbSNP
rs1309100204 79 dbSNP
rs1289272460 84 dbSNP
rs1432089075 86 dbSNP
rs1013557174 87 dbSNP
rs956278161 92 dbSNP
rs1472940018 98 dbSNP
rs754583277 107 dbSNP
rs533141775 108 dbSNP
rs1304537405 115 dbSNP
rs1417931069 117 dbSNP
rs917357114 124 dbSNP
rs1252531132 125 dbSNP
rs1002394627 133 dbSNP
rs1027148981 134 dbSNP
rs951928070 134 dbSNP
rs950233043 140 dbSNP
rs1357351737 141 dbSNP
rs144389970 143 dbSNP
rs551738684 146 dbSNP
rs1324381025 153 dbSNP
rs961701132 154 dbSNP
rs980702157 160 dbSNP
rs927509263 161 dbSNP
rs1289590155 179 dbSNP
rs975697047 184 dbSNP
rs8198 187 dbSNP
rs755140098 188 dbSNP
rs1297075880 191 dbSNP
rs1406260065 192 dbSNP
rs1392432702 193 dbSNP
rs779116650 194 dbSNP
rs1156439267 196 dbSNP
rs1287809258 199 dbSNP
rs1452496243 207 dbSNP
rs1412029634 211 dbSNP
rs1401475189 213 dbSNP
rs1479435914 214 dbSNP
rs748158390 215 dbSNP
rs1268038913 217 dbSNP
rs1300360340 221 dbSNP
rs1339069247 223 dbSNP
rs1199327216 229 dbSNP
rs1244597360 231 dbSNP
rs1285284674 236 dbSNP
rs931887456 238 dbSNP
rs1359129311 242 dbSNP
rs1292375442 246 dbSNP
rs1238007790 249 dbSNP
rs1048726734 251 dbSNP
rs1328641436 252 dbSNP
rs1268882031 253 dbSNP
rs1488708004 254 dbSNP
rs1321260069 258 dbSNP
rs1050254787 260 dbSNP
rs1219079483 262 dbSNP
rs1254416613 264 dbSNP
rs769351840 266 dbSNP
rs1188046601 268 dbSNP
rs1370075201 274 dbSNP
rs772259646 276 dbSNP
rs778127830 277 dbSNP
rs773246246 279 dbSNP
rs1052537987 283 dbSNP
rs936462525 283 dbSNP
rs1421057967 285 dbSNP
rs747597857 291 dbSNP
rs531610491 292 dbSNP
rs1395781170 299 dbSNP
rs1335313508 300 dbSNP
rs1385557279 302 dbSNP
rs1445233748 303 dbSNP
rs1308540501 304 dbSNP
rs1354499219 306 dbSNP
rs1242465017 312 dbSNP
rs1013608057 313 dbSNP
rs1254452190 317 dbSNP
rs747387767 320 dbSNP
rs1200770229 321 dbSNP
rs1258023762 324 dbSNP
rs1456331942 329 dbSNP
rs1240122749 331 dbSNP
rs550111144 335 dbSNP
rs1177923521 336 dbSNP
rs1046411191 337 dbSNP
rs1210675727 338 dbSNP
rs1238773485 339 dbSNP
rs901610617 344 dbSNP
rs568479772 345 dbSNP
rs548558916 346 dbSNP
rs1376678505 347 dbSNP
rs1220290871 348 dbSNP
rs1050234978 350 dbSNP
rs777087662 362 dbSNP
rs1002456556 365 dbSNP
rs1173464558 369 dbSNP
rs774260392 369 dbSNP
rs1408764568 375 dbSNP
rs535919251 379 dbSNP
rs1027613358 386 dbSNP
rs1331245587 389 dbSNP
rs755505042 391 dbSNP
rs1449920162 392 dbSNP
rs888632555 392 dbSNP
rs759992603 393 dbSNP
rs768361911 396 dbSNP
rs1004760193 398 dbSNP
rs1330682487 399 dbSNP
rs34730851 401 dbSNP
rs1258053069 402 dbSNP
rs1417239910 406 dbSNP
rs1315817138 407 dbSNP
rs1167120837 409 dbSNP
rs1449775020 415 dbSNP
rs1197827857 418 dbSNP
rs1258602652 422 dbSNP
rs1190737794 427 dbSNP
rs1391088948 427 dbSNP
rs1459064146 430 dbSNP
rs1188902648 437 dbSNP
rs770028719 438 dbSNP
rs1460073298 453 dbSNP
rs1000739876 455 dbSNP
rs1236940535 456 dbSNP
rs1210853714 463 dbSNP
rs1444662199 465 dbSNP
rs1030915231 470 dbSNP
rs956058332 478 dbSNP
rs1204902700 481 dbSNP
rs551266508 487 dbSNP
rs35475536 488 dbSNP
rs1243294308 491 dbSNP
rs1377862133 496 dbSNP
rs1029944362 512 dbSNP
rs953334431 517 dbSNP
rs1352691167 523 dbSNP
rs34916824 524 dbSNP
rs986068579 531 dbSNP
rs1430228993 533 dbSNP
rs971907842 534 dbSNP
rs1320296605 538 dbSNP
rs980238623 555 dbSNP
rs927456152 556 dbSNP
rs925158385 557 dbSNP
rs1473781370 562 dbSNP
rs35155991 563 dbSNP
rs1231745838 568 dbSNP
rs1293166923 568 dbSNP
rs1490997742 570 dbSNP
rs952236882 581 dbSNP
rs182245314 583 dbSNP
rs1220670504 584 dbSNP
rs558078855 587 dbSNP
rs1177431340 590 dbSNP
rs940349774 591 dbSNP
rs1229600267 595 dbSNP
rs1040461195 596 dbSNP
rs1370522398 597 dbSNP
rs914011419 604 dbSNP
rs1409840548 607 dbSNP
rs756992697 608 dbSNP
rs949434520 609 dbSNP
rs1352209264 614 dbSNP
rs1421861123 617 dbSNP
rs576634719 620 dbSNP
rs931731337 622 dbSNP
rs1046473644 627 dbSNP
rs905198844 638 dbSNP
rs1050177373 639 dbSNP
rs1366083349 643 dbSNP
rs1426541731 644 dbSNP
rs1349523540 647 dbSNP
rs1165748802 650 dbSNP
rs536662353 652 dbSNP
rs903692947 653 dbSNP
rs1306243338 655 dbSNP
rs767624664 656 dbSNP
rs1354022980 663 dbSNP
rs1254521014 667 dbSNP
rs1197717981 669 dbSNP
rs1000689570 670 dbSNP
rs1281521511 671 dbSNP
rs1052291529 673 dbSNP
rs1266971612 679 dbSNP
rs892402489 687 dbSNP
rs1331160576 688 dbSNP
rs888672470 689 dbSNP
rs1386075540 695 dbSNP
rs1368029975 699 dbSNP
rs139461795 699 dbSNP
rs1024742512 705 dbSNP
rs1438838242 710 dbSNP
rs1386679493 711 dbSNP
rs971473874 712 dbSNP
rs1001625340 714 dbSNP
rs1414918784 717 dbSNP
rs1174559231 718 dbSNP
rs1433016564 720 dbSNP
rs1426269904 721 dbSNP
rs1316218517 725 dbSNP
rs1484700595 730 dbSNP
rs1246966788 731 dbSNP
rs3181215 737 dbSNP
rs952176396 738 dbSNP
rs984978682 744 dbSNP
rs1436756187 746 dbSNP
rs149442005 750 dbSNP
rs1029996704 752 dbSNP
rs1234237334 755 dbSNP
rs962619553 761 dbSNP
rs1320136375 768 dbSNP
rs188200557 769 dbSNP
rs1301645222 772 dbSNP
rs1182751711 777 dbSNP
rs1032275939 780 dbSNP
rs192759741 795 dbSNP
rs183656671 803 dbSNP
rs1178703496 808 dbSNP
rs1446305179 810 dbSNP
rs931687850 812 dbSNP
rs1418841743 814 dbSNP
rs555188204 817 dbSNP
rs545175609 822 dbSNP
rs1450850326 824 dbSNP
rs753964705 830 dbSNP
rs1199350106 833 dbSNP
rs188532199 834 dbSNP
rs982202566 836 dbSNP
rs376797856 842 dbSNP
rs1202263705 844 dbSNP
rs530801637 845 dbSNP
rs925062910 850 dbSNP
rs192196572 851 dbSNP
rs1337738330 853 dbSNP
rs1367566295 854 dbSNP
rs562143519 858 dbSNP
rs1385442828 859 dbSNP
rs529256934 860 dbSNP
rs1395465910 867 dbSNP
rs1403539854 869 dbSNP
rs1270155763 870 dbSNP
rs1340748474 878 dbSNP
rs1214618134 882 dbSNP
rs1048858274 885 dbSNP
rs547527095 890 dbSNP
rs760538560 892 dbSNP
rs1370319664 900 dbSNP
rs879887140 902 dbSNP
rs1202649357 903 dbSNP
rs1168881328 908 dbSNP
rs184735335 913 dbSNP
rs1366302777 917 dbSNP
rs1186244495 920 dbSNP
rs1423883700 926 dbSNP
rs1258247123 930 dbSNP
rs189551906 944 dbSNP
rs1037240649 946 dbSNP
rs1045696075 950 dbSNP
rs147532320 956 dbSNP
rs765798350 960 dbSNP
rs1263832550 961 dbSNP
rs1212781111 964 dbSNP
rs1238559696 968 dbSNP
rs998274220 970 dbSNP
rs1341129542 975 dbSNP
rs191302208 978 dbSNP
rs1051473841 993 dbSNP
rs1034413479 994 dbSNP
rs537776355 995 dbSNP
rs1007248033 998 dbSNP
rs1412003253 1000 dbSNP
rs1388140602 1009 dbSNP
rs555769970 1015 dbSNP
rs1423171281 1017 dbSNP
rs1469424583 1019 dbSNP
rs1162267875 1021 dbSNP
rs1458011769 1034 dbSNP
rs878971770 1041 dbSNP
rs184499563 1042 dbSNP
rs1472235245 1044 dbSNP
rs1184083142 1046 dbSNP
rs1015514044 1053 dbSNP
rs1265610155 1054 dbSNP
rs768597850 1055 dbSNP
rs1209446422 1070 dbSNP
rs1357197109 1070 dbSNP
rs1275164177 1071 dbSNP
rs1226597615 1077 dbSNP
rs1408698176 1078 dbSNP
rs958013673 1079 dbSNP
rs962279428 1080 dbSNP
rs534595255 1082 dbSNP
rs1020851380 1083 dbSNP
rs1392366092 1088 dbSNP
rs776313346 1089 dbSNP
rs1317969385 1090 dbSNP
rs3214580 1092 dbSNP
rs397750662 1092 dbSNP
rs1412700913 1093 dbSNP
rs200532695 1093 dbSNP
rs1161270316 1096 dbSNP
rs1318122779 1104 dbSNP
rs117451491 1109 dbSNP
rs1030616592 1110 dbSNP
rs953036681 1111 dbSNP
rs1255057404 1112 dbSNP
rs985784021 1114 dbSNP
rs75044810 1116 dbSNP
rs925010597 1122 dbSNP
rs758802857 1125 dbSNP
rs939996338 1126 dbSNP
rs1037253293 1132 dbSNP
rs780643423 1136 dbSNP
rs987959965 1137 dbSNP
rs1372726564 1142 dbSNP
rs577769948 1143 dbSNP
rs1433784341 1146 dbSNP
rs1388703629 1152 dbSNP
rs949289442 1155 dbSNP
rs1322518101 1156 dbSNP
rs1263395199 1157 dbSNP
rs1325304273 1164 dbSNP
rs78297051 1177 dbSNP
rs11555009 1178 dbSNP
rs1478850004 1179 dbSNP
rs1447452088 1185 dbSNP
rs1186883584 1186 dbSNP
rs888897788 1188 dbSNP
rs937299497 1191 dbSNP
rs1007712530 1195 dbSNP
rs1195245161 1197 dbSNP
rs555951448 1198 dbSNP
rs1480164799 1200 dbSNP
rs1200293126 1202 dbSNP
rs1278450599 1206 dbSNP
rs1431681300 1209 dbSNP
rs1201449924 1210 dbSNP
rs1350483679 1212 dbSNP
rs542942534 1214 dbSNP
rs887825950 1220 dbSNP
rs1365427182 1226 dbSNP
rs1271457991 1228 dbSNP
rs1006312474 1229 dbSNP
rs777400829 1230 dbSNP
rs1015047431 1232 dbSNP
rs897980084 1243 dbSNP
rs1436420899 1249 dbSNP
rs748850246 1251 dbSNP
rs1167684502 1258 dbSNP
rs1030982861 1259 dbSNP
rs770990621 1261 dbSNP
rs1386146618 1262 dbSNP
rs1390957581 1263 dbSNP
rs1188360364 1269 dbSNP
rs1471846969 1278 dbSNP
rs985731916 1287 dbSNP
rs1047167 1292 dbSNP
rs1188825386 1299 dbSNP
rs1402880824 1302 dbSNP
rs774491761 1307 dbSNP
rs755244366 1314 dbSNP
rs957746886 1318 dbSNP
rs1274595993 1322 dbSNP
rs1403773310 1323 dbSNP
rs988295315 1327 dbSNP
rs1226186226 1331 dbSNP
rs1355022333 1333 dbSNP
rs561016929 1334 dbSNP
rs1416576387 1341 dbSNP
rs1347001106 1345 dbSNP
rs1348500785 1349 dbSNP
rs949221849 1354 dbSNP
rs1410128192 1355 dbSNP
rs1236504908 1356 dbSNP
rs1172781681 1360 dbSNP
rs1403723199 1371 dbSNP
rs1278669057 1378 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Flp-In T-REx 293-hAGO1 cells
Location of target site 3'UTR
Original Description (Extracted from the article) ... Validation of interactions identified by CLASH suppports their reliability. ...

- Helwak A; Kudla G; Dudnakova T; Tollervey D, 2013, Cell.

Article - Helwak A; Kudla G; Dudnakova T; Tollervey D
- Cell, 2013
MicroRNAs (miRNAs) play key roles in gene regulation, but reliable bioinformatic or experimental identification of their targets remains difficult. To provide an unbiased view of human miRNA targets, we developed a technique for ligation and sequencing of miRNA-target RNA duplexes associated with human AGO1. Here, we report data sets of more than 18,000 high-confidence miRNA-mRNA interactions. The binding of most miRNAs includes the 5' seed region, but around 60% of seed interactions are noncanonical, containing bulged or mismatched nucleotides. Moreover, seed interactions are generally accompanied by specific, nonseed base pairing. 18% of miRNA-mRNA interactions involve the miRNA 3' end, with little evidence for 5' contacts, and some of these were functionally validated. Analyses of miRNA:mRNA base pairing showed that miRNA species systematically differ in their target RNA interactions, and strongly overrepresented motifs were found in the interaction sites of several miRNAs. We speculate that these affect the response of RISC to miRNA-target binding.
LinkOut: [PMID: 23622248]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
PRAD -0.75 0.02 -0.786 0.01 8 Click to see details
HNSC -0.512 0.02 -0.368 0.08 16 Click to see details
LUAD 0.473 0.1 0.367 0.17 9 Click to see details
LIHC 0.298 0.1 0.220 0.18 20 Click to see details
KICH -0.339 0.11 -0.179 0.26 15 Click to see details
KIRP 0.28 0.14 0.115 0.33 17 Click to see details
BRCA -0.16 0.14 -0.143 0.17 46 Click to see details
KIRC -0.204 0.15 -0.131 0.26 27 Click to see details
BLCA 0.291 0.19 0.345 0.15 11 Click to see details
UCEC 0.326 0.2 0.017 0.48 9 Click to see details
THCA -0.098 0.25 -0.176 0.12 48 Click to see details
CHOL -0.687 0.26 -0.500 0.33 3 Click to see details
LUSC -0.11 0.31 -0.073 0.37 23 Click to see details
PAAD -0.329 0.39 -0.500 0.33 3 Click to see details
STAD -0.062 0.4 -0.195 0.22 18 Click to see details
STAD -0.062 0.4 -0.195 0.22 18 Click to see details
STAD -0.062 0.4 -0.195 0.22 18 Click to see details
STAD -0.062 0.4 -0.195 0.22 18 Click to see details
STAD -0.062 0.4 -0.195 0.22 18 Click to see details
STAD -0.062 0.4 -0.195 0.22 18 Click to see details
107 hsa-miR-605-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT001230 SEC24D SEC24 homolog D, COPII coat complex component 3 1
MIRT016155 TP53 tumor protein p53 2 1
MIRT016156 TCEAL1 transcription elongation factor A like 1 1 1
MIRT016157 MDM2 MDM2 proto-oncogene 2 1
MIRT040476 YBX1 Y-box binding protein 1 1 1
MIRT040477 TMEM64 transmembrane protein 64 1 1
MIRT040478 KDM5C lysine demethylase 5C 1 1
MIRT040479 TRAF4 TNF receptor associated factor 4 1 1
MIRT040480 DRG1 developmentally regulated GTP binding protein 1 1 1
MIRT040481 BCL9 B-cell CLL/lymphoma 9 1 1
MIRT055125 SCD stearoyl-CoA desaturase 2 2
MIRT057521 CEP55 centrosomal protein 55 2 2
MIRT081129 LDLR low density lipoprotein receptor 2 6
MIRT096817 ZSWIM6 zinc finger SWIM-type containing 6 2 4
MIRT100961 CENPQ centromere protein Q 2 4
MIRT263338 ANAPC16 anaphase promoting complex subunit 16 2 2
MIRT274710 CPSF6 cleavage and polyadenylation specific factor 6 2 2
MIRT311193 ANKRD33B ankyrin repeat domain 33B 2 2
MIRT360127 DEK DEK proto-oncogene 2 2
MIRT438269 PSMD10 proteasome 26S subunit, non-ATPase 10 2 1
MIRT442464 SLC25A13 solute carrier family 25 member 13 2 2
MIRT446110 TSC22D2 TSC22 domain family member 2 2 2
MIRT463119 ZNF507 zinc finger protein 507 2 2
MIRT470566 POU2F1 POU class 2 homeobox 1 2 2
MIRT475059 IVNS1ABP influenza virus NS1A binding protein 2 6
MIRT482538 ACTB actin beta 2 4
MIRT494136 DCAF7 DDB1 and CUL4 associated factor 7 2 6
MIRT495209 EDN3 endothelin 3 2 2
MIRT495235 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT496762 MANBAL mannosidase beta like 2 2
MIRT498885 ZNF12 zinc finger protein 12 2 10
MIRT499280 NBPF11 NBPF member 11 2 2
MIRT507063 H3F3B H3 histone family member 3B 2 2
MIRT508352 HES7 hes family bHLH transcription factor 7 2 8
MIRT510740 SMC1A structural maintenance of chromosomes 1A 2 6
MIRT519872 ZFP62 ZFP62 zinc finger protein 2 4
MIRT521272 RTN4 reticulon 4 2 4
MIRT522324 NFIB nuclear factor I B 2 6
MIRT525011 ACTN4 actinin alpha 4 2 6
MIRT526608 AASDH aminoadipate-semialdehyde dehydrogenase 2 4
MIRT529043 ARL9 ADP ribosylation factor like GTPase 9 2 2
MIRT529545 ZNF678 zinc finger protein 678 2 2
MIRT532500 HOXA13 homeobox A13 2 2
MIRT532599 SIX4 SIX homeobox 4 2 2
MIRT534044 STK4 serine/threonine kinase 4 2 2
MIRT534087 SPPL3 signal peptide peptidase like 3 2 2
MIRT534249 SLC16A1 solute carrier family 16 member 1 2 2
MIRT534286 SLC12A7 solute carrier family 12 member 7 2 2
MIRT534555 RUNX1 runt related transcription factor 1 2 2
MIRT536765 HOXB2 homeobox B2 2 2
MIRT537227 GAN gigaxonin 2 2
MIRT551105 TTC8 tetratricopeptide repeat domain 8 2 2
MIRT552247 DUSP3 dual specificity phosphatase 3 2 2
MIRT554361 SFXN5 sideroflexin 5 2 2
MIRT557402 H3F3C H3 histone family member 3C 2 2
MIRT559116 C16orf52 chromosome 16 open reading frame 52 2 2
MIRT560494 BUB3 BUB3, mitotic checkpoint protein 2 2
MIRT562296 GLO1 glyoxalase I 2 2
MIRT562597 CAPZA2 capping actin protein of muscle Z-line alpha subunit 2 2 2
MIRT563857 ALYREF Aly/REF export factor 2 4
MIRT565665 SIX1 SIX homeobox 1 2 2
MIRT568253 BTF3L4 basic transcription factor 3 like 4 2 2
MIRT609593 GPM6B glycoprotein M6B 2 2
MIRT611552 GGT6 gamma-glutamyltransferase 6 2 2
MIRT613451 CYLD CYLD lysine 63 deubiquitinase 2 2
MIRT615516 PRRC2A proline rich coiled-coil 2A 2 2
MIRT617766 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT619134 MCOLN3 mucolipin 3 2 2
MIRT621365 CAP2 cyclase associated actin cytoskeleton regulatory protein 2 2 2
MIRT625804 MDC1 mediator of DNA damage checkpoint 1 2 2
MIRT626954 PRDM2 PR/SET domain 2 2 2
MIRT627716 RCAN1 regulator of calcineurin 1 2 2
MIRT628069 KCNJ13 potassium voltage-gated channel subfamily J member 13 2 2
MIRT630451 GTPBP8 GTP binding protein 8 (putative) 2 2
MIRT635533 ELMOD2 ELMO domain containing 2 2 2
MIRT636206 SULF2 sulfatase 2 2 2
MIRT638763 EPHA4 EPH receptor A4 2 2
MIRT640324 STAT1 signal transducer and activator of transcription 1 2 2
MIRT644548 SPOP speckle type BTB/POZ protein 2 2
MIRT645114 TMX2 thioredoxin related transmembrane protein 2 2 2
MIRT647778 NANOS1 nanos C2HC-type zinc finger 1 2 2
MIRT650112 ZCCHC9 zinc finger CCHC-type containing 9 2 2
MIRT650136 ABCB7 ATP binding cassette subfamily B member 7 2 2
MIRT650310 SLC35E2 solute carrier family 35 member E2 2 2
MIRT650930 ST6GALNAC1 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 2 2
MIRT651018 ZNF740 zinc finger protein 740 2 2
MIRT653541 SLC38A9 solute carrier family 38 member 9 2 2
MIRT655752 NR2C2 nuclear receptor subfamily 2 group C member 2 2 2
MIRT656908 KIAA1958 KIAA1958 2 2
MIRT657854 GJD3 gap junction protein delta 3 2 2
MIRT658215 FBXO21 F-box protein 21 2 2
MIRT659884 CAPN7 calpain 7 2 2
MIRT659922 CACNA1E calcium voltage-gated channel subunit alpha1 E 2 2
MIRT660055 C12orf5 TP53 induced glycolysis regulatory phosphatase 1 1
MIRT664616 LIMD1 LIM domains containing 1 2 2
MIRT665392 WEE1 WEE1 G2 checkpoint kinase 2 2
MIRT667887 IP6K1 inositol hexakisphosphate kinase 1 2 2
MIRT669018 CHORDC1 cysteine and histidine rich domain containing 1 2 2
MIRT688419 DUSP2 dual specificity phosphatase 2 2 2
MIRT691888 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT709530 GEN1 GEN1, Holliday junction 5' flap endonuclease 2 2
MIRT711013 ABCD2 ATP binding cassette subfamily D member 2 2 2
MIRT714731 CENPH centromere protein H 2 2
MIRT719897 PTGIS prostaglandin I2 synthase 2 2
MIRT725028 CX3CL1 C-X3-C motif chemokine ligand 1 2 2
MIRT734348 P2RY12 purinergic receptor P2Y12 3 0
MIRT736719 TNFAIP3 TNF alpha induced protein 3 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-605 Anthranilamide-pyrazolo[1,5-a]pyrimidine NULL NULL Quantitative real-time PCR neuroblastoma cells 23992861 2013 up-regualted
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-605 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-605 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-605 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-mir-605 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-605-5p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-605-5p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-605-5p Navitoclax 24978538 NSC759659 sensitive High Colorectal Cancer cell line (HCT-116, CHL1)
hsa-miR-605-5p Gemcitabine 60750 NSC613327 approved sensitive Low Pancreatic Cancer cell line (BxPC‐3, PANC‐1)
hsa-miR-605-5p Paclitaxel 36314 NSC125973 approved sensitive High Non-Small Cell Lung Cancer cell line (H358, H1155)
hsa-miR-605-5p Cisplatin 5460033 NSC119875 approved sensitive High Gastric Cancer tissue
hsa-miR-605-5p Fluorouracil 3385 NSC19893 approved sensitive High Gastric Cancer tissue
hsa-miR-605-5p Fluorouracil 3385 NSC19893 approved resistant Low Colon Cancer cell line (HT-29, LoVo)
hsa-miR-605-5p Everolimus + Panobinostat sensitive Low Clear Cell Renal Cell Carcinoma tissue
hsa-miR-605-5p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-605-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-605-5p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-605-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)
hsa-miR-605-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-605-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-605-5p 4-Hydroxytamoxifen+Tamoxifen sensitive cell line (LY2)
hsa-miR-605-5p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-605-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (SKOV3)
hsa-miR-605-5p Pegylated interferon alpha+Ribavirin sensitive tissue (chronic hepatitis C)
hsa-miR-605-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (IGROV-1)
hsa-miR-605-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-605-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-605-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-605-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (OVCAR3)
hsa-miR-605-5p Cisplatin 5460033 NSC119875 approved resistant cell line (H460)
hsa-miR-605-5p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)

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