miRTarBase - #MIRT041086


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pre-miRNA Information
pre-miRNA hsa-mir-504   
Genomic Coordinates chrX: 138667711 - 138667793
Synonyms MIRN504, hsa-mir-504, MIR504
Description Homo sapiens miR-504 stem-loop
Comment The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-504-5p
Sequence 13| AGACCCUGGUCUGCACUCUAUC |34
Evidence Experimental
Experiments Array-cloned
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1297440872 6 dbSNP
rs1429220261 12 dbSNP
rs745623382 14 dbSNP
rs770027520 14 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol BRD2   
Synonyms BRD2-IT1, D6S113E, FSH, FSRG1, NAT, O27.1.1, RING3, RNF3
Description bromodomain containing 2
Transcript NM_005104   
Other Transcripts NM_001113182   
Expression
Putative miRNA Targets on BRD2
3'UTR of BRD2
(miRNA target sites are highlighted)		 
>BRD2|NM_005104|3'UTR
   1 GGGGTCAGGCCAGATGGGGCAGGAAGGCTCCGCAGGACCGGACCCCTAGACCACCCTGCCCCACCTGCCCCTTCCCCCTT
  81 TGCTGTGACACTTCTTCATCTCACCCCCCCCCGCCCCCCTCTAGGAGAGCTGGCTCTGCAGTGGGGGAGGGATGCAGGGA
 161 CATTTACTGAAGGAGGGACATGGACAAAACAACATTGAATTCCCAGCCCCATTGGGGAGTGATCTCTTGGACACAGAGCC
 241 CCCATTCAAAATGGGGCAGGGCAAGGGTGGGAGTGTGCAAAGCCCTGATCTGGAGTTACCTGAGGCCACAGCTGCCCTAT
 321 TCACTTCTAAGGGCCCTGTTTTGAGATTGTTTGTTCTAATTTATTTTAAGCTAGGTAAGGCTGGGGGGAGGGTGGGGCCG
 401 TGGTCCCCTCAGCCTCCATGGGGAGGGAAGAAGGGGGAGCTCTTTTTTTACGTTGATTTTTTTTTTTCTACTCTGTTTTC
 481 CCTTTTTCCTTCCGCTCCATTTGGGGCCCTGGGGGTTTCAGTCATCTCCCCATTTGGTCCCCTGGACTGTCTTTGTTGAT
 561 TCTAACTTGTAAATAAAGAAAATATTATTCAAGTTTTGAGTTACCTTAATATTTGCTTTTGTAGTGTTTCAAAAGGAACA
 641 TCATAAGAATTGTCTTGATAATTTTGAGGGAAATATTACTGCAGTGAGAAAAGGCAATAGCTAACCTATAATTGGATTGT
 721 CTTAATTTTTAAACCAGTAGGCTTTTGCTGTGTTTTTAATAAAGTAAATATGACTTTTGTAAATTGAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cuaUCUCACGUCUGGUCCCAGa 5'
             ||:||| :|:||: |||| 
Target 5' gggAGGGTG-GGGCCGTGGTCc 3'
 386 - 406 122.00 -22.00
2 
miRNA  3' cuAUCUCACGUCUG-GUCCCAGa 5'
            |:|:|   :||: ||||| | 
Target 5' agTGGGGGAGGGATGCAGGGACa 3'
 140 - 162 120.00 -15.12
3 
miRNA  3' cuaUCUCACGU-CUGGUCCCAga 5'
             | :| ||| |:| |||||  
Target 5' aaaATGGGGCAGGGCAAGGGTgg 3'
 248 - 270 111.00 -17.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26968037 22 COSMIC
COSN8892472 32 COSMIC
COSN26968044 33 COSMIC
COSN30489393 45 COSMIC
COSN30484424 46 COSMIC
COSN26968040 47 COSMIC
COSN30466747 56 COSMIC
COSN26968043 58 COSMIC
COSN26968038 71 COSMIC
COSN30450533 78 COSMIC
COSN18731024 83 COSMIC
COSN18730989 106 COSMIC
COSN18731025 113 COSMIC
COSN31496325 128 COSMIC
COSN28773066 227 COSMIC
COSN25587564 260 COSMIC
COSN30177246 344 COSMIC
COSN30172332 411 COSMIC
COSN20102726 468 COSMIC
COSN20102727 468 COSMIC
COSN9780764 619 COSMIC
rs1049526 310 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1328214125 2 dbSNP
rs200531629 3 dbSNP
rs371782351 4 dbSNP
rs755712112 5 dbSNP
rs779702404 6 dbSNP
rs748984841 10 dbSNP
rs776114924 12 dbSNP
rs973448897 13 dbSNP
rs1286444034 15 dbSNP
rs1337960491 16 dbSNP
rs1212323087 17 dbSNP
rs201611634 18 dbSNP
rs1273198679 19 dbSNP
rs1342449290 26 dbSNP
rs1406872024 28 dbSNP
rs199587809 32 dbSNP
rs1255224629 33 dbSNP
rs747933045 35 dbSNP
rs1188225554 36 dbSNP
rs1454070221 40 dbSNP
rs771907245 41 dbSNP
rs773143264 42 dbSNP
rs1168047899 43 dbSNP
rs1365312513 44 dbSNP
rs769903589 45 dbSNP
rs1431929291 47 dbSNP
rs1171972440 48 dbSNP
rs775526678 49 dbSNP
rs1396994234 50 dbSNP
rs200408799 52 dbSNP
rs1425458802 53 dbSNP
rs1200907094 54 dbSNP
rs201062187 54 dbSNP
rs1267313340 55 dbSNP
rs199866893 56 dbSNP
rs1222376571 58 dbSNP
rs1333997961 63 dbSNP
rs550492304 68 dbSNP
rs572040517 69 dbSNP
rs1237393084 70 dbSNP
rs1316510519 75 dbSNP
rs1284204216 76 dbSNP
rs937461550 82 dbSNP
rs147269908 83 dbSNP
rs1295718850 84 dbSNP
rs554100245 87 dbSNP
rs1000069582 88 dbSNP
rs1032805988 89 dbSNP
rs1382706917 90 dbSNP
rs1387102249 91 dbSNP
rs776038649 91 dbSNP
rs1364667732 92 dbSNP
rs917470471 94 dbSNP
rs575656392 95 dbSNP
rs1429469214 96 dbSNP
rs867257671 98 dbSNP
rs1178159832 102 dbSNP
rs1427979551 103 dbSNP
rs891557750 103 dbSNP
rs1193799108 104 dbSNP
rs1264503252 104 dbSNP
rs1485751347 104 dbSNP
rs5875429 104 dbSNP
rs201692899 105 dbSNP
rs1282531157 106 dbSNP
rs1205793926 107 dbSNP
rs1010370479 108 dbSNP
rs1041767764 108 dbSNP
rs1029345963 109 dbSNP
rs199530843 110 dbSNP
rs543676741 111 dbSNP
rs1049414 113 dbSNP
rs28986268 113 dbSNP
rs1191686833 114 dbSNP
rs201992712 114 dbSNP
rs1284791820 115 dbSNP
rs997067889 117 dbSNP
rs973551071 119 dbSNP
rs1029538785 120 dbSNP
rs1448520302 121 dbSNP
rs577496683 122 dbSNP
rs929426349 124 dbSNP
rs1004101861 129 dbSNP
rs1015525577 132 dbSNP
rs139189753 145 dbSNP
rs1226599873 146 dbSNP
rs1383487045 148 dbSNP
rs1422001762 150 dbSNP
rs917328394 154 dbSNP
rs1454429059 156 dbSNP
rs1316859103 160 dbSNP
rs1194999333 172 dbSNP
rs1392719128 181 dbSNP
rs1381532787 184 dbSNP
rs973412932 187 dbSNP
rs1411099840 188 dbSNP
rs72865897 191 dbSNP
rs1172510866 194 dbSNP
rs1386264578 195 dbSNP
rs1429640817 196 dbSNP
rs1044413624 201 dbSNP
rs905779792 208 dbSNP
rs1386463768 213 dbSNP
rs1402832490 215 dbSNP
rs958839714 222 dbSNP
rs935868501 225 dbSNP
rs78300601 227 dbSNP
rs1439843955 237 dbSNP
rs762901594 239 dbSNP
rs10829 242 dbSNP
rs891598362 243 dbSNP
rs1329427826 245 dbSNP
rs766274925 248 dbSNP
rs548705381 250 dbSNP
rs1358485437 253 dbSNP
rs1010050875 257 dbSNP
rs1280095720 264 dbSNP
rs372641732 265 dbSNP
rs1333663359 267 dbSNP
rs1206641140 270 dbSNP
rs890879090 275 dbSNP
rs1006516857 283 dbSNP
rs530944039 290 dbSNP
rs935656046 291 dbSNP
rs1305500758 296 dbSNP
rs1054074104 297 dbSNP
rs1413519956 298 dbSNP
rs1017862573 301 dbSNP
rs552573999 307 dbSNP
rs1049526 310 dbSNP
rs1181495634 316 dbSNP
rs1490534775 318 dbSNP
rs370640038 320 dbSNP
rs1220145334 323 dbSNP
rs563816342 325 dbSNP
rs890925884 328 dbSNP
rs1225303127 330 dbSNP
rs1004474919 334 dbSNP
rs1471425934 337 dbSNP
rs557249314 339 dbSNP
rs565873583 342 dbSNP
rs983631773 344 dbSNP
rs764140608 347 dbSNP
rs1349854595 349 dbSNP
rs201572601 351 dbSNP
rs1388792363 356 dbSNP
rs1386303768 357 dbSNP
rs11555939 360 dbSNP
rs971467334 362 dbSNP
rs1803596 364 dbSNP
rs1337506144 372 dbSNP
rs865882857 375 dbSNP
rs994819959 379 dbSNP
rs1217631342 383 dbSNP
rs1445072296 387 dbSNP
rs1027694507 389 dbSNP
rs959034555 389 dbSNP
rs980105914 392 dbSNP
rs1218148493 393 dbSNP
rs1367464535 395 dbSNP
rs1271288317 396 dbSNP
rs971560806 400 dbSNP
rs185910133 401 dbSNP
rs977588231 403 dbSNP
rs1470409841 405 dbSNP
rs924848486 405 dbSNP
rs112975861 406 dbSNP
rs1174307283 408 dbSNP
rs1414010329 414 dbSNP
rs935920202 415 dbSNP
rs1188186655 416 dbSNP
rs766285020 430 dbSNP
rs373317674 432 dbSNP
rs753895863 442 dbSNP
rs1184024580 443 dbSNP
rs989767509 446 dbSNP
rs1054394017 450 dbSNP
rs1234862843 451 dbSNP
rs913132013 452 dbSNP
rs945912177 453 dbSNP
rs1260895657 457 dbSNP
rs1307580292 457 dbSNP
rs3841159 457 dbSNP
rs561765216 457 dbSNP
rs932313501 457 dbSNP
rs113758837 458 dbSNP
rs1050843949 459 dbSNP
rs1297299155 463 dbSNP
rs554261704 468 dbSNP
rs1484358277 471 dbSNP
rs939854412 471 dbSNP
rs575769479 473 dbSNP
rs199828295 474 dbSNP
rs1251648450 475 dbSNP
rs1006568535 479 dbSNP
rs1167492126 480 dbSNP
rs1408118494 483 dbSNP
rs867833406 489 dbSNP
rs531286752 490 dbSNP
rs898190267 493 dbSNP
rs1457569159 494 dbSNP
rs995122677 495 dbSNP
rs1803863 506 dbSNP
rs34128205 507 dbSNP
rs1180907684 510 dbSNP
rs894438287 510 dbSNP
rs191209130 515 dbSNP
rs1307374444 519 dbSNP
rs1355958302 522 dbSNP
rs1201891632 524 dbSNP
rs1340604043 528 dbSNP
rs1274593511 529 dbSNP
rs1247091128 531 dbSNP
rs1362060692 532 dbSNP
rs546525540 534 dbSNP
rs115821350 537 dbSNP
rs1310271497 539 dbSNP
rs1005462885 541 dbSNP
rs1227681796 542 dbSNP
rs1252637708 543 dbSNP
rs757327670 544 dbSNP
rs1408109513 545 dbSNP
rs971911294 546 dbSNP
rs1339446422 548 dbSNP
rs1203766335 550 dbSNP
rs971484501 551 dbSNP
rs1426533849 552 dbSNP
rs1383153218 554 dbSNP
rs1163861777 559 dbSNP
rs577459044 563 dbSNP
rs1419281747 570 dbSNP
rs1031833793 572 dbSNP
rs1174934739 574 dbSNP
rs766254450 575 dbSNP
rs980156717 575 dbSNP
rs927341647 579 dbSNP
rs990321052 583 dbSNP
rs921531308 584 dbSNP
rs1254507292 585 dbSNP
rs1317697715 587 dbSNP
rs541720800 588 dbSNP
rs957386272 590 dbSNP
rs1226588684 593 dbSNP
rs559643540 596 dbSNP
rs1392213113 597 dbSNP
rs755277977 598 dbSNP
rs1284075795 599 dbSNP
rs1427929039 605 dbSNP
rs945952831 606 dbSNP
rs1388554075 610 dbSNP
rs1051386114 611 dbSNP
rs1168012287 613 dbSNP
rs1292683106 616 dbSNP
rs182780962 620 dbSNP
rs1346536535 624 dbSNP
rs542307476 627 dbSNP
rs912297755 633 dbSNP
rs1300921016 634 dbSNP
rs1378185864 636 dbSNP
rs765491877 638 dbSNP
rs1036860257 639 dbSNP
rs750631198 640 dbSNP
rs187202774 644 dbSNP
rs1262925791 650 dbSNP
rs531052705 651 dbSNP
rs1049639 658 dbSNP
rs886697068 673 dbSNP
rs1328799221 674 dbSNP
rs16871296 677 dbSNP
rs1225454960 680 dbSNP
rs1300513690 681 dbSNP
rs1024911536 684 dbSNP
rs1363804685 689 dbSNP
rs907390874 689 dbSNP
rs1212845044 694 dbSNP
rs1456356430 699 dbSNP
rs60466011 701 dbSNP
rs1001689198 707 dbSNP
rs895083845 708 dbSNP
rs1034465826 709 dbSNP
rs957404504 720 dbSNP
rs1221975856 723 dbSNP
rs1198757839 724 dbSNP
rs1447851832 725 dbSNP
rs1188079131 731 dbSNP
rs990566009 734 dbSNP
rs73409643 735 dbSNP
rs1205568550 745 dbSNP
rs1342984735 746 dbSNP
rs1255547292 760 dbSNP
rs1434919273 760 dbSNP
rs1173869452 761 dbSNP
rs1358461038 762 dbSNP
rs532263294 766 dbSNP
rs967720241 772 dbSNP
rs998861297 775 dbSNP
rs1434128106 778 dbSNP
rs986759853 780 dbSNP
rs1386055065 781 dbSNP
rs1338309544 784 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Flp-In T-REx 293-hAGO1 cells
Location of target site CDS
Original Description (Extracted from the article) ... Validation of interactions identified by CLASH suppports their reliability. ...

- Helwak A; Kudla G; Dudnakova T; Tollervey D, 2013, Cell.

Article - Helwak A; Kudla G; Dudnakova T; Tollervey D
- Cell, 2013
MicroRNAs (miRNAs) play key roles in gene regulation, but reliable bioinformatic or experimental identification of their targets remains difficult. To provide an unbiased view of human miRNA targets, we developed a technique for ligation and sequencing of miRNA-target RNA duplexes associated with human AGO1. Here, we report data sets of more than 18,000 high-confidence miRNA-mRNA interactions. The binding of most miRNAs includes the 5' seed region, but around 60% of seed interactions are noncanonical, containing bulged or mismatched nucleotides. Moreover, seed interactions are generally accompanied by specific, nonseed base pairing. 18% of miRNA-mRNA interactions involve the miRNA 3' end, with little evidence for 5' contacts, and some of these were functionally validated. Analyses of miRNA:mRNA base pairing showed that miRNA species systematically differ in their target RNA interactions, and strongly overrepresented motifs were found in the interaction sites of several miRNAs. We speculate that these affect the response of RISC to miRNA-target binding.
LinkOut: [PMID: 23622248]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
STAD -0.558 0 -0.691 0 24 Click to see details
BLCA 0.63 0.01 0.560 0.02 14 Click to see details
PAAD 0.899 0.05 1.000 0.5 4 Click to see details
CHOL 0.634 0.06 0.607 0.07 7 Click to see details
ESCA -0.744 0.07 -0.700 0.09 5 Click to see details
BRCA -0.154 0.11 -0.200 0.06 65 Click to see details
COAD 0.631 0.13 0.600 0.14 5 Click to see details
UCEC 0.27 0.17 0.339 0.11 15 Click to see details
LUSC 0.183 0.17 0.255 0.09 29 Click to see details
HNSC -0.17 0.19 -0.138 0.24 28 Click to see details
LIHC 0.087 0.29 0.063 0.34 43 Click to see details
KICH -0.104 0.31 -0.155 0.23 25 Click to see details
KIRC 0.07 0.31 0.057 0.35 51 Click to see details
LUAD 0.162 0.32 0.109 0.37 11 Click to see details
PRAD 0.063 0.33 0.111 0.22 50 Click to see details
THCA 0.04 0.39 0.103 0.24 49 Click to see details
KIRP -0.043 0.41 0.013 0.47 28 Click to see details
KIRP -0.043 0.41 0.013 0.47 28 Click to see details
KIRP -0.043 0.41 0.013 0.47 28 Click to see details
KIRP -0.043 0.41 0.013 0.47 28 Click to see details
KIRP -0.043 0.41 0.013 0.47 28 Click to see details
101 hsa-miR-504-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT000044 DRD1 dopamine receptor D1 2 1
MIRT004457 VEGFA vascular endothelial growth factor A 2 1
MIRT016249 BAX BCL2 associated X, apoptosis regulator 1 1
MIRT016251 GADD45A growth arrest and DNA damage inducible alpha 1 1
MIRT016252 FAS Fas cell surface death receptor 1 1
MIRT016253 BBC3 BCL2 binding component 3 1 1
MIRT016254 TP53I3 tumor protein p53 inducible protein 3 1 1
MIRT016255 TCEAL1 transcription elongation factor A like 1 2 1
MIRT016256 MDM2 MDM2 proto-oncogene 2 1
MIRT016257 TP53 tumor protein p53 3 1
MIRT041072 P2RY13 purinergic receptor P2Y13 1 1
MIRT041073 PPIL1 peptidylprolyl isomerase like 1 1 1
MIRT041074 ZNF814 zinc finger protein 814 1 1
MIRT041075 HIST1H2AC histone cluster 1 H2A family member c 1 1
MIRT041076 FEM1A fem-1 homolog A 1 1
MIRT041077 TXNRD1 thioredoxin reductase 1 1 1
MIRT041078 RAI1 retinoic acid induced 1 1 1
MIRT041079 SRRM2 serine/arginine repetitive matrix 2 1 1
MIRT041080 HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 1 1
MIRT041081 PDLIM1 PDZ and LIM domain 1 1 1
MIRT041082 FAM208B family with sequence similarity 208 member B 1 1
MIRT041083 PSAT1 phosphoserine aminotransferase 1 1 1
MIRT041084 TMEM8A transmembrane protein 8A 1 1
MIRT041085 RABGAP1 RAB GTPase activating protein 1 1 1
MIRT041086 BRD2 bromodomain containing 2 1 1
MIRT041087 C11orf58 chromosome 11 open reading frame 58 1 1
MIRT041088 CNOT8 CCR4-NOT transcription complex subunit 8 1 1
MIRT041089 RPL10 ribosomal protein L10 1 1
MIRT041090 SMCR7L mitochondrial elongation factor 1 1 1
MIRT041091 CENPBD1 CENPB DNA-binding domain containing 1 1 1
MIRT041092 SF3B1 splicing factor 3b subunit 1 1 1
MIRT041093 MTFP1 mitochondrial fission process 1 1 1
MIRT438313 CDK6 cyclin dependent kinase 6 1 1
MIRT438352 TFF1 trefoil factor 1 3 1
MIRT443009 KBTBD12 kelch repeat and BTB domain containing 12 2 2
MIRT448052 SFRP1 secreted frizzled related protein 1 2 2
MIRT457649 ZNF69 zinc finger protein 69 2 2
MIRT458626 TRIM72 tripartite motif containing 72 2 2
MIRT466176 TMED5 transmembrane p24 trafficking protein 5 2 2
MIRT472583 NACC1 nucleus accumbens associated 1 2 2
MIRT473576 MAT2A methionine adenosyltransferase 2A 2 6
MIRT485155 RASL10B RAS like family 10 member B 2 2
MIRT490063 PRRT2 proline rich transmembrane protein 2 2 2
MIRT493015 NANOS1 nanos C2HC-type zinc finger 1 2 2
MIRT499425 PLCG2 phospholipase C gamma 2 2 11
MIRT506956 HOXB3 homeobox B3 2 4
MIRT507100 GPCPD1 glycerophosphocholine phosphodiesterase 1 2 2
MIRT508101 ANKRD33B ankyrin repeat domain 33B 2 4
MIRT522215 NR2C2 nuclear receptor subfamily 2 group C member 2 2 6
MIRT530327 TNFRSF10D TNF receptor superfamily member 10d 2 2
MIRT531042 ZNF502 zinc finger protein 502 2 2
MIRT532580 GSS glutathione synthetase 2 2
MIRT534841 RAB15 RAB15, member RAS oncogene family 2 2
MIRT536820 HMGN2 high mobility group nucleosomal binding domain 2 2 2
MIRT538303 CSNK2A1 casein kinase 2 alpha 1 2 2
MIRT546344 TFAP2C transcription factor AP-2 gamma 2 2
MIRT546704 RORA RAR related orphan receptor A 2 4
MIRT549222 BCL2L11 BCL2 like 11 2 4
MIRT549623 TMEM101 transmembrane protein 101 2 2
MIRT549931 NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 2 2
MIRT550163 ZNF223 zinc finger protein 223 2 4
MIRT550555 ARSK arylsulfatase family member K 2 2
MIRT553402 TRIM2 tripartite motif containing 2 2 4
MIRT554084 SNX4 sorting nexin 4 2 4
MIRT556962 IER3IP1 immediate early response 3 interacting protein 1 2 2
MIRT558525 CSRNP3 cysteine and serine rich nuclear protein 3 2 2
MIRT558565 CRLF3 cytokine receptor like factor 3 2 4
MIRT560946 TPM4 tropomyosin 4 2 4
MIRT561628 SERBP1 SERPINE1 mRNA binding protein 1 2 2
MIRT562174 HOXA13 homeobox A13 2 2
MIRT568635 ACVR2A activin A receptor type 2A 2 2
MIRT574908 Plcg2 phospholipase C, gamma 2 2 7
MIRT575177 Atg9a autophagy related 9A 2 2
MIRT611972 PKD1 polycystin 1, transient receptor potential channel interacting 2 2
MIRT613623 CLASP1 cytoplasmic linker associated protein 1 2 4
MIRT635830 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 4
MIRT637344 DARS2 aspartyl-tRNA synthetase 2, mitochondrial 2 4
MIRT643205 JAK3 Janus kinase 3 2 2
MIRT650232 SIGLEC9 sialic acid binding Ig like lectin 9 2 2
MIRT655940 NDUFA4P1 NDUFA4, mitochondrial complex associated pseudogene 1 2 2
MIRT662021 ZNF445 zinc finger protein 445 2 2
MIRT662037 FUT2 fucosyltransferase 2 2 2
MIRT666873 POU2F2 POU class 2 homeobox 2 2 2
MIRT684310 TRUB2 TruB pseudouridine synthase family member 2 2 2
MIRT687333 OSMR oncostatin M receptor 2 2
MIRT689008 ATP6AP1 ATPase H+ transporting accessory protein 1 2 2
MIRT695137 PRY2 PTPN13-like, Y-linked 2 2 2
MIRT695154 PRY PTPN13-like, Y-linked 2 2
MIRT700695 POLR3D RNA polymerase III subunit D 2 2
MIRT703269 GNL3L G protein nucleolar 3 like 2 2
MIRT708941 CRY2 cryptochrome circadian clock 2 2 2
MIRT709200 SAPCD2 suppressor APC domain containing 2 2 2
MIRT709572 PDE4A phosphodiesterase 4A 2 2
MIRT711295 PSME3 proteasome activator subunit 3 2 2
MIRT712425 MACROD2 MACRO domain containing 2 2 2
MIRT713941 PIGR polymeric immunoglobulin receptor 2 2
MIRT714124 TMED9 transmembrane p24 trafficking protein 9 2 2
MIRT714630 KIAA1143 KIAA1143 2 2
MIRT724046 SMIM14 small integral membrane protein 14 2 2
MIRT724649 PKDREJ polycystin family receptor for egg jelly 2 2
MIRT725476 GRAP2 GRB2-related adaptor protein 2 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-504 Emodin NULL 3220 Microarray K562 cells 23744534 2013 down-regualted
miR-504 Mistletoe lectin-I NULL NULL Microarray colorectal cancer cells CLY cells 20955366 2011 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-504 Ceritinib 57379345 NSC776422 approved sensitive High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-504 Androstenedione+Anastrozole resistant cell line (MCF-7)
hsa-mir-504 Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)
hsa-miR-504-5p Oxaliplatin 6857599 NSC266046 approved resistant High Colorectal Cancer cell line (HT-29)
hsa-miR-504-5p Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer cell line (RKO)
hsa-miR-504-5p Plx-4720 24180719 NSC757438 sensitive High Thyroid Cancer cell line (8505c, BCPAP)
hsa-miR-504-5p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-504-5p Dabrafenib 44462760 NSC764134 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-504-5p Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-504-5p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-504-5p Ceritinib 57379345 NSC776422 approved sensitive High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-504-5p Fulvestrant 17756771 NSC719276 approved sensitive High Breast Cancer cell line (MCF-7, MCF-7-TT)
hsa-miR-504-5p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-504-5p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-504-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (A375)
hsa-miR-504-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-miR-504-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-504-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM47)
hsa-miR-504-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM16)
hsa-miR-504-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM17)
hsa-miR-504-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (CIS)
hsa-miR-504-5p Cisplatin 5460033 NSC119875 approved resistant cell line (MGC-803)
hsa-miR-504-5p Ethanol+Tamoxifen sensitive cell line (LY2)
hsa-miR-504-5p Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-miR-504-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-504-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-504-5p Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)
hsa-miR-504-5p Cisplatin 5460033 NSC119875 approved resistant cell line (H460)

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