miRTarBase - #MIRT050011


—
pre-miRNA Information
pre-miRNA hsa-mir-28   
Genomic Coordinates chr3: 188688781 - 188688866
Synonyms MIRN28, hsa-mir-28, miR-28, MIR28
Description Homo sapiens miR-28 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-28-5p
Sequence 14| AAGGAGCUCACAGUCUAUUGAG |35
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 2 3 + 188688795 29233923 MiREDiBase
A-to-I 5 3 + 188688798 29233923 MiREDiBase
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN18185224 6 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1466099417 7 dbSNP
rs1333243027 9 dbSNP
rs1211406812 12 dbSNP
rs1380324091 13 dbSNP
rs1350747725 14 dbSNP
rs564264103 17 dbSNP
rs1315387654 18 dbSNP
rs1380847802 20 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SMYD1   
Synonyms BOP, KMT3D, ZMYND18, ZMYND22
Description SET and MYND domain containing 1
Transcript NM_198274   
Expression
Putative miRNA Targets on SMYD1
3'UTR of SMYD1
(miRNA target sites are highlighted)		 
>SMYD1|NM_198274|3'UTR
   1 GGACTGCCCAGTGGAGGAGGGGCGATGTGGCTGGGGAGCTAGGGAGAGACTCTGGAGGTGGTGGGTCTCTCGGGAGACCC
  81 CTAATGAGGAAGTTGAGGTAATGCTTAACATTGTTGCTGTGAGAATTTACTGCCCTATGTTTCCCAGAGCCATTTTGGCT
 161 CAATTCAAGTCTATTCAATTCAAGTTAACTCTAGCCCAGCCCAGATCAACTCCTCCTACAAATATTATTGGATGATAGGC
 241 CCTAGAACCCAATAAAGGAGCTCCAAATGTCGTTGGGTGGGGAAGCAAAATGTAGAGAAACATTTAAAGCACACTGTAAT
 321 AATAAATGCAATTATAAACTATATGGAGGAGGGTGCAGAGGAGGGAATGTGTCTGGTGTGTGATGTGTGTGTGTGCAGTG
 401 GGGGTATCACAGAGAGTATGACATCTGAGTTGAGGGTAGCAGGTGCCTGGAGTCTCAGGTGGCTGCTCACCCATCTGTGC
 481 AGGTGTCTCTGGGGCTGCTGGTCTCACCTGTGGTCTGCAGTAGACACAATTGGCTGAGCAGGATATGTGATACTGTGTGG
 561 TTGGTGTGGAGTTTTGAAGAAGGGGCTGTGTTTGGGCCACGTAGGCTCTACTCAGAGACCTGAAACCACTTCAGAATGGT
 641 GCATATGTCGAAAGAGCTGGCTGGGGGCCTTGCCCAAACCAACTGAGGTCTTAAAGTCCAGGGAAAAAAAGTCTGGGTTC
 721 CAACTAGAATTCTAGAAATATTTCTAGAACACACAGAGAGGGAATAAGTCCCTCTATCACCCTTATTACCAAGCCTTGTG
 801 GTTCCCTGTGATTTTAGATAATGTCTGATATTTTTCTGGCTATTTGCCTAGTAGGATTTAAAAAATATTTTCAAAGTGAA
 881 GCTGAGAGAGAATCTTGGAAACACACATACCTGTTGATCATGGGCCCTGCAGAATTGGCCCTTGGGGGCTTTATTTGGTT
 961 ACATGTGCCTGGGTGGTCTTTACCAGCTTAGACTCTATCATGGGCCCCCATGAAGCTCCATTCTCAATACTGAATAATTA
1041 TTACTTCCCTTGTTGAGTTTCTTTTTCTGTCATGCCCTGGGGGCTTCTGCTCTTCTCACCAGAAAGAACATTTGAATCTG
1121 GATTCTTGTACACCTGGGTTAGACCCTGTTCAGAGGTGTGGCCAATTTATCCCGATCTCCTGGAAGGCTGTTGTGATTTC
1201 CATCTAAGAAATGAGGGTCTTGAGAATCAACCAGTCCCAAGATTAGCCTGTTATCCTGTTATCTACTGAGACCCCAAATT
1281 TCTCACCAATGTTTTGGGAGATCCTGGAAAAGATCCCTTCAGTTTGGGGTGTCACCAAGACTTCTACACAACCCAGGACT
1361 ACCATTGACCTCAGAGCTGTACCCCACATCTTGAAGTAAATTGATCCCACCAGGTCCCACGTTTGTTATCTCTGCCTAAA
1441 TGTTAGCTTCTCCATCCTCACCACATGATGACCTGCTGTGTCCCTCTGAGCACTACCCAGTGGCTGAAAACTCTGCAAAT
1521 GGGCCACACTTTTGCAAAATACTTGTATCTGACACTTAGGTCTTGTTTGAAGAATTTCCTTTCTGGAAGGTTTTACAAGA
1601 AGACTGATAGTCTTTCAAGCCCCCACATCACAGGCTTAGGGACGGCACTAACTTTCTCCCAGGGATCTAACTGGCTAGTT
1681 CAAATTATCACTCTTTTACCTTCATATAAAATGTCTCCCCCAAACCTTTTTCCCTTCTTTGTCATTGTTATCTGCTAAGC
1761 CCCTGGTCATTTCCCCATATTCGTAGTCTTTTTTTCCATCCTATCTTTCTAATATTTGTTGTCTTTAACAAACTGTGTTC
1841 TGTGTCTGTGCTCCTCCTTCCCTCTCAGACCACTGGAATGCAAGTCCTTCTTCCCTTTGGAATGTACTCTGGATCCCTTC
1921 CCCTGCTTTGACCCCCAGACTTTGCTCCATCTATTATTGCTTCTCCATCCTGGATCCTTGACATTTGTCACCCCACTGGC
2001 CTTCTCAGGTGCAATCAGTAAAAATGCTGAGAACTCTTGGATCTTAATCTTCATGACTGAGTTTTTTTTAGTTGTATAGT
2081 TATCATCTGCCTTTCTTCACTTTGCATTTCTTCTTGAATCCATTGCAGATTGACTTCCACTCCCACTCCTTCACTAAAAG
2161 GGCTCTTACCAAGATCAAATCTAATGGGTACATTTTAGTTCCTATGTGATTTGGCCTTTCGATGTCAATCATCACTCCCA
2241 GCCATTGATTTTGGTGACCCACTTCCCTGTGATGATCTTCTGATCTAGTTTCTCAGGTTCCTTCGCTGGTCCTTTTTCTT
2321 TCCCTGCCCCTGACATATTGACATTTCCTGGAGTTGGTTTTGTCCTTGATTCATTCTCATGTCATTCTGCACACAGTCTC
2401 TGCATGAACTCAGGCAGACCCTTCATTTAATGACCACCTTAGGGCTGATGATTCTCAAATCTGTATTCCCCGATCTTGCA
2481 TTTGAGCTCCAGCCCCACTCATCCTCTCGGATGTTCTGCAGGCCCAGCAAACTCATCATGTCCAAAGTGAAACTTTTTCT
2561 CTTTCCTGTCTCCTCTCCTCTGATCTGTTCTTTCTTGGAACACCACCCAAGAACGTCACCTCCTCCATCAGATTGTGAGC
2641 TCCTGGAGGGCAGGAGCTGTGTCCTTCTATTCATCTTCCTATCCCCAGAACCTTGCACAGATCCTGGAATGTGGTAGGTG
2721 CTCAGTAAATGTGTGTTGAATAAATGAATGAATGAATGAACAAATGAATGAATTTGCTTACTTCAAGGCAAAAGAACCAT
2801 GAAACTGTATTTTGAGTTTCTATGTTATAGCAGTCAGCAAATCCTATTAAATACTTTGTGTTTCCAAGCAAAAAAAAAAA
2881 AAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gaGUUAUCUGACACUCGAGGAa 5'
            ||  |||:||||||||||| 
Target 5' tcCATCAGATTGTGAGCTCCTg 3'
 2624 - 2645 180.00 -25.80
2 
miRNA  3' gaGUUAUC--UG-ACACUCGAGGAa 5'
            :|||:|  || | | ||:|||| 
Target 5' tcTAATGGGTACATTTTAGTTCCTa 3'
 2180 - 2204 142.00 -9.62
3 
miRNA  3' gaguuAUCUGACACUCGAGGAa 5'
               || | ||| ||||:|| 
Target 5' ctgccTA-AATGTTAGCTTCTc 3'
 1432 - 1452 140.00 -9.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM6858561 1 COSMIC
COSN30536589 23 COSMIC
COSN30140616 24 COSMIC
COSN31602411 25 COSMIC
COSN30611068 44 COSMIC
COSN31496545 51 COSMIC
COSN1861815 58 COSMIC
COSN28670855 72 COSMIC
COSN31958583 74 COSMIC
COSN30133698 77 COSMIC
COSN30133744 78 COSMIC
COSN6685308 138 COSMIC
COSN21242953 273 COSMIC
COSN14515270 405 COSMIC
COSN25389778 568 COSMIC
COSN17190547 606 COSMIC
COSN24371210 1277 COSMIC
COSN21665759 1358 COSMIC
COSN31486070 1377 COSMIC
COSN9392128 1419 COSMIC
COSN30086457 1422 COSMIC
COSN31595263 1467 COSMIC
COSN31593578 1473 COSMIC
COSN8868384 1575 COSMIC
COSN30539866 1579 COSMIC
COSN26897747 1587 COSMIC
COSN28784585 1605 COSMIC
COSN31489926 1644 COSMIC
COSN17076487 1656 COSMIC
COSN14011661 1664 COSMIC
COSN14842987 1766 COSMIC
COSN9392129 1863 COSMIC
COSN5962135 1902 COSMIC
COSN18888538 2009 COSMIC
COSN1861816 2020 COSMIC
COSN5962136 2177 COSMIC
COSN5962137 2221 COSMIC
COSN20738229 2331 COSMIC
COSN22384748 2485 COSMIC
COSN32097748 2643 COSMIC
COSN1861817 2686 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs538751929 2 dbSNP
rs1185564942 6 dbSNP
rs1478186617 7 dbSNP
rs1247891436 8 dbSNP
rs1233078674 10 dbSNP
rs779262564 12 dbSNP
rs1181169773 15 dbSNP
rs750307400 16 dbSNP
rs199889323 17 dbSNP
rs765404188 18 dbSNP
rs752786219 22 dbSNP
rs149175661 23 dbSNP
rs202241112 24 dbSNP
rs1355282542 25 dbSNP
rs1444470035 27 dbSNP
rs1271397384 34 dbSNP
rs752050855 36 dbSNP
rs1257268281 38 dbSNP
rs757829432 39 dbSNP
rs951760136 43 dbSNP
rs1345983395 45 dbSNP
rs1247440654 46 dbSNP
rs898207285 49 dbSNP
rs1317739009 51 dbSNP
rs1403201850 53 dbSNP
rs561539762 59 dbSNP
rs1478508919 61 dbSNP
rs572893051 63 dbSNP
rs1368460736 71 dbSNP
rs2289497 72 dbSNP
rs1426872171 75 dbSNP
rs1170245014 78 dbSNP
rs1002803849 79 dbSNP
rs1411668283 81 dbSNP
rs1332645182 89 dbSNP
rs975816314 92 dbSNP
rs769693575 93 dbSNP
rs1445211407 98 dbSNP
rs1231466624 102 dbSNP
rs958735348 112 dbSNP
rs1306139845 116 dbSNP
rs921710421 117 dbSNP
rs931720470 120 dbSNP
rs1021620209 122 dbSNP
rs564706041 128 dbSNP
rs1289125693 134 dbSNP