miRTarBase - #MIRT054859


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pre-miRNA Information
pre-miRNA hsa-mir-497   
Genomic Coordinates chr17: 7017911 - 7018022
Synonyms MIRN497, hsa-mir-497, MIR497
Description Homo sapiens miR-497 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-497-5p
Sequence 24| CAGCAGCACACUGUGGUUUGU |44
Evidence Experimental
Experiments Array-cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 2 17 - 7017998 22499667, 24964909, 25582055, 25692236, 27229138, 28411194, 28550310, 29267965, 30022565, 29976955, 29165639, 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1217216293 1 dbSNP
rs1050536403 10 dbSNP
rs1283992109 11 dbSNP
rs1239642436 12 dbSNP
rs753897817 16 dbSNP
rs1315164260 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol CHEK1   
Synonyms CHK1
Description checkpoint kinase 1
Transcript NM_001114122   
Other Transcripts NM_001114121 , NM_001274   
Expression
Putative miRNA Targets on CHEK1
3'UTR of CHEK1
(miRNA target sites are highlighted)		 
>CHEK1|NM_001114122|3'UTR
   1 TCGGACCATCGGCTCTGGGGAATCCTGGTGAATATAGTGCTGCTATGTTGACATTATTCTTCCTAGAGAAGATTATCCTG
  81 TCCTGCAAACTGCAAATAGTAGTTCCTGAAGTGTTCACTTCCCTGTTTATCCAAACATCTTCCAATTTATTTTGTTTGTT
 161 CGGCATACAAATAATACCTATATCTTAATTGTAAGCAAAACTTTGGGGAAAGGATGAATAGAATTCATTTGATTATTTCT
 241 TCATGTGTGTTTAGTATCTGAATTTGAAACTCATCTGGTGGAAACCAAGTTTCAGGGGACATGAGTTTTCCAGCTTTTAT
 321 ACACACGTATCTCATTTTTATCAAAACATTTTGTTTAATTCAAAAAGTACATATTCCATGTTGATTTAATTCTAAGATGA
 401 ACCAATAAAGACATAATTCTTGTGACTTTTGGACAGTAGATTTATCAGTCTGTGAAGCGAAGCCAGCTTCAAAACATATC
 481 CCCAAGATTTGTACTTATATTTTCAAAAGGGCCTGGCCAGTTATATAAACCTGTTTTTGAATTATAATGATTAATTAAAA
 561 TTGCAAGTAGGTGTTTTTTCCAGTGTAGTTAGTAAAATACTTGTATTTTACAGTGTTGCATAAACTCTAGTGCTTAACTA
 641 ACTTTACTCTAAAAATTACTGTTGAACATCTTAAATATTTTTCTATATTTTCTACTTTCATAGCCATATTTTAACCTTTT
 721 CAACTTACTGGTGACCAAGCTTTTAGGTGATAAAGAATAAAAGAGGGAAGGGAAGAGTAAGGAAGCTATAAGAAAAATAG
 801 ATCTGATTCTTTGTTCCTTTACCTGTTAGACTTACAAAAAGTTTGTTTTTCTAATAAAATTTGTATCAACTTTGGGGCAT
 881 ATTAGGTTGAGGCCTTGGCTCCTGCCTGTAGTCCCAGCTACTTAGGAGGCTGAGAGAGGAGGATCGCGTGAACCTGGAAG
 961 TTTGAGGCTGTAGTGAGCTATGATTGCACCAGTGCACTCCAGCTTGGATGACAGAGTAAGACCCTACCTCTAATAAAAAT
1041 TTTTAAAATTGTAAAACATTATAAAATTAATCAGTTATTTTAATCTGAAGCCAAGAACATGTAGAATGTTATGATTAGAG
1121 TTTATCACATATTAATGTATACTGGCAAATTGTGTTACTGGAGTATACCCATAGGAGGAATAAATTCAAACCTGTTTTAT
1201 TTATTTGAACCTATTTACGGTATGCTTAAGAATTGAATCAGTATAAATTCTCAAATATGGGAGAAATTTTGTTCTTGAGA
1281 ATTATCTGAGTCATTAATATTTTTCAAAAACAGCTCTCACTGACTTGAACCTCTTCTGTAAGCTCTAACCTTTTACCTGC
1361 TTTACATTTCCACTTGAATGTCTAGTAGGCATCTCTTGACCAAAAACAGCTTTTGATTCCTGTTCTCCAACCTGTTCCTC
1441 TCCTAGTTTTCTCCATCTCAGAAATGTTACTTCCTCTGCAAAGTCTTTCCCTGACTTATCTAAAATAATAACCTCCTCTG
1521 TTTGCTGTGGGAATTTGTATAGAATGGTGGGAAAATTTCAAGTTTCATATTTGGATTAGCTCTGACATTTATTTATCTGA
1601 ACACTGGTAATTGCCTCAGTAAAGACACTGATAATAAGTACCTTTTAGAGTTATTTTAATCTTTAATGCTTTAATGTGTA
1681 GGAAGAGTATAGTGTCCTGTTTTGCACAGAAAGGCATTCTGTAAATAATAAGTTGCCTTAATTTTCCTGTAATGTTCATT
1761 ATATTGTTGTGGGAAGGTATTTACTCCTATTATTAAAAATAAAAATGTGTAAAATTTACTACCTGAAAAAAAAAAAAAAA
1841 AAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ugUUUGGUGUCA-------CACGACGAc 5'
            :||:| ::||       |||||||| 
Target 5' ggGAATCCTGGTGAATATAGTGCTGCTa 3'
 18 - 45 151.00 -14.01
2 
miRNA  3' ugUUUGGUGUCACACGACGAc 5'
            |:| :|:||||| |||:| 
Target 5' gaAGAGTATAGTGTCCTGTTt 3'
 1682 - 1702 127.00 -15.40
3 
miRNA  3' uguuuGGUGUCACACGACGac 5'
               || | || |||||:  
Target 5' aacctCCTCTGTTTGCTGTgg 3'
 1510 - 1530 120.00 -11.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26575252 4 COSMIC
COSN26556998 13 COSMIC
COSN31600859 24 COSMIC
COSN30158938 26 COSMIC
COSN30179292 28 COSMIC
COSN30179290 29 COSMIC
COSN31613997 36 COSMIC
COSN26970625 58 COSMIC
COSN30460365 84 COSMIC
COSN31564405 127 COSMIC
COSN26671781 155 COSMIC
COSN31605508 162 COSMIC
COSN1128439 371 COSMIC
COSN20108960 376 COSMIC
COSN8736231 935 COSMIC
COSN25658961 1250 COSMIC
COSN27293215 1826 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1461079315 2 dbSNP
rs746474609 3 dbSNP
rs373998065 4 dbSNP
rs1032047014 5 dbSNP
rs780645711 8 dbSNP
rs747973479 11 dbSNP
rs748831574 12 dbSNP
rs749279821 14 dbSNP
rs1379752146 17 dbSNP
rs573744071 21 dbSNP
rs375887872 23 dbSNP
rs1453372998 25 dbSNP
rs1177289255 27 dbSNP
rs760632598 31 dbSNP
rs1296278154 34 dbSNP
rs764381233 37 dbSNP
rs776659228 44 dbSNP
rs1397834579 48 dbSNP
rs769434607 53 dbSNP
rs9282658 62 dbSNP
rs952890763 80 dbSNP
rs1383282654 86 dbSNP
rs1182803697 88 dbSNP
rs1285677542 90 dbSNP
rs1444978164 94 dbSNP
rs148807246 96 dbSNP
rs1202753914 98 dbSNP
rs1257439035 100 dbSNP
rs1260282320 103 dbSNP
rs868300535 112 dbSNP
rs1018498934 117 dbSNP
rs528501689 119 dbSNP
rs1313514770 124 dbSNP
rs976752552 128 dbSNP
rs547243050 132 dbSNP
rs373169887 137 dbSNP
rs1245738497 139 dbSNP
rs1185444197 141 dbSNP
rs566608597 144 dbSNP
rs967472656 162 dbSNP
rs1440480505 163 dbSNP
rs545410689 165 dbSNP
rs961200994 167 dbSNP
rs184393295 168 dbSNP
rs1288996773 181 dbSNP
rs925778195 182 dbSNP
rs1363674707 190 dbSNP
rs1433947874 227 dbSNP
rs1162802614 236 dbSNP
rs1358449867 251 dbSNP
rs1369909741 256 dbSNP
rs937212660 257 dbSNP
rs1303399900 270 dbSNP
rs530886491 273 dbSNP
rs1194524971 286 dbSNP
rs1401362524 295 dbSNP
rs1055553794 300 dbSNP
rs551019927 302 dbSNP
rs762754025 303 dbSNP
rs917138297 311 dbSNP
rs567785939 320 dbSNP
rs1377194929 325 dbSNP
rs142447277 327 dbSNP
rs1040471427 328 dbSNP
rs1036004503 330 dbSNP
rs546900560 335 dbSNP
rs1343032866 342 dbSNP
rs897513387 351 dbSNP
rs901934954 368 dbSNP
rs1405549905 372 dbSNP
rs141464656 372 dbSNP
rs113628894 374 dbSNP
rs199723723 374 dbSNP
rs3731480 374 dbSNP
rs201914580 377 dbSNP
rs1165988339 384 dbSNP
rs1461266556 393 dbSNP
rs994580634 400 dbSNP
rs1171589699 413 dbSNP
rs778999496 414 dbSNP
rs190098261 424 dbSNP
rs746593482 427 dbSNP
rs566817329 433 dbSNP
rs1257116570 434 dbSNP
rs892931725 435 dbSNP
rs1483176648 440 dbSNP
rs1339090288 441 dbSNP
rs1258323332 445 dbSNP
rs181773130 447 dbSNP
rs1198805611 460 dbSNP
rs1320960403 464 dbSNP
rs1011511727 470 dbSNP
rs1007031214 474 dbSNP
rs1022875058 476 dbSNP
rs557311968 477 dbSNP
rs867477773 481 dbSNP
rs571357048 485 dbSNP
rs536760417 494 dbSNP
rs1458257673 495 dbSNP
rs1390626647 505 dbSNP
rs1035314960 512 dbSNP
rs1378667515 517 dbSNP
rs184932784 525 dbSNP
rs1467433618 529 dbSNP
rs1427436159 531 dbSNP
rs1176460827 534 dbSNP
rs998869350 535 dbSNP
rs1020269576 561 dbSNP
rs1464426378 569 dbSNP
rs1026499237 574 dbSNP
rs573756240 581 dbSNP
rs978811178 585 dbSNP
rs531003966 591 dbSNP
rs1239245813 598 dbSNP
rs1200891775 605 dbSNP
rs925998849 614 dbSNP
rs1262086017 625 dbSNP
rs536408620 627 dbSNP
rs943414991 641 dbSNP
rs796283040 646 dbSNP
rs923231958 648 dbSNP
rs1377549826 660 dbSNP
rs552083132 674 dbSNP
rs1311246212 687 dbSNP
rs1450148898 694 dbSNP
rs1404227733 700 dbSNP
rs1388896449 708 dbSNP
rs1336264376 718 dbSNP
rs991252163 721 dbSNP
rs570698696 727 dbSNP
rs1156885807 729 dbSNP
rs892998671 730 dbSNP
rs771819651 734 dbSNP
rs113311223 744 dbSNP
rs918927650 745 dbSNP
rs1443124777 762 dbSNP
rs905781244 768 dbSNP
rs776907998 772 dbSNP
rs189829306 783 dbSNP
rs1198048265 785 dbSNP
rs1048767326 789 dbSNP
rs1489557570 801 dbSNP
rs537919085 808 dbSNP
rs1288022429 810 dbSNP
rs896789185 810 dbSNP
rs1431220464 814 dbSNP
rs1007335617 818 dbSNP
rs1172778733 824 dbSNP
rs151312608 839 dbSNP
rs993953816 849 dbSNP
rs1424198947 853 dbSNP
rs1039856921 858 dbSNP
rs952281786 864 dbSNP
rs1167841670 866 dbSNP
rs549875618 871 dbSNP
rs984923724 887 dbSNP
rs998438095 888 dbSNP
rs1020992549 895 dbSNP
rs903447742 896 dbSNP
rs1160925923 901 dbSNP
rs1423145620 906 dbSNP
rs545446097 915 dbSNP
rs1384930241 921 dbSNP
rs140546391 922 dbSNP
rs1032986172 923 dbSNP
rs1473607950 934 dbSNP
rs144047942 946 dbSNP
rs567889 947 dbSNP
rs867555391 948 dbSNP
rs368655022 949 dbSNP
rs971677146 950 dbSNP
rs988944790 953 dbSNP
rs1341628002 955 dbSNP
rs1218107471 966 dbSNP
rs561393899 971 dbSNP
rs1268601050 972 dbSNP
rs530272683 973 dbSNP
rs1399503558 979 dbSNP
rs1323581880 987 dbSNP
rs1222663973 988 dbSNP
rs914637377 1000 dbSNP
rs34215005 1004 dbSNP
rs1300593475 1005 dbSNP
rs146445217 1018 dbSNP
rs551723322 1028 dbSNP
rs1165978004 1029 dbSNP
rs984433707 1039 dbSNP
rs1166897737 1040 dbSNP
rs927080479 1040 dbSNP
rs1477414696 1053 dbSNP
rs938596460 1058 dbSNP
rs1196627164 1065 dbSNP
rs1490179143 1070 dbSNP
rs1247187638 1073 dbSNP
rs1057412025 1077 dbSNP
rs1435819396 1085 dbSNP
rs1271166799 1091 dbSNP
rs867617337 1101 dbSNP
rs560443248 1105 dbSNP
rs1318868650 1109 dbSNP
rs370171293 1113 dbSNP
rs896845485 1116 dbSNP
rs910246133 1120 dbSNP
rs140816182 1121 dbSNP
rs1347716742 1133 dbSNP
rs1423156691 1138 dbSNP
rs1040559377 1140 dbSNP
rs1300374712 1144 dbSNP
rs552421232 1146 dbSNP
rs1048183188 1150 dbSNP
rs1361742416 1154 dbSNP
rs1425294398 1167 dbSNP
rs1189216717 1170 dbSNP
rs1173691372 1172 dbSNP
rs1432055258 1176 dbSNP
rs1425819515 1190 dbSNP
rs773225208 1192 dbSNP
rs1192795100 1196 dbSNP
rs1400004414 1211 dbSNP
rs1479539900 1212 dbSNP
rs1268924766 1214 dbSNP
rs901335616 1215 dbSNP
rs888197735 1216 dbSNP
rs934112906 1219 dbSNP
rs1041895640 1220 dbSNP
rs1381498057 1223 dbSNP
rs1017741795 1236 dbSNP
rs565362064 1252 dbSNP
rs1311618759 1258 dbSNP
rs1302589675 1268 dbSNP
rs1221495673 1272 dbSNP
rs1371792226 1282 dbSNP
rs997748107 1286 dbSNP
rs1447935595 1287 dbSNP
rs1030992149 1289 dbSNP
rs1334235867 1290 dbSNP
rs528324506 1292 dbSNP
rs535067031 1301 dbSNP
rs1000422066 1315 dbSNP
rs914545162 1319 dbSNP
rs1218518953 1320 dbSNP
rs1032956466 1321 dbSNP
rs968801474 1329 dbSNP
rs894508571 1333 dbSNP
rs1179066512 1338 dbSNP
rs1286554540 1344 dbSNP
rs1013001066 1345 dbSNP
rs1024771987 1351 dbSNP
rs1441263637 1358 dbSNP
rs980156664 1376 dbSNP
rs971515016 1378 dbSNP
rs763049367 1381 dbSNP
rs1180266399 1383 dbSNP
rs766801457 1385 dbSNP
rs1483044508 1411 dbSNP
rs1487831828 1413 dbSNP
rs761790614 1417 dbSNP
rs1285885772 1419 dbSNP
rs1026172464 1423 dbSNP
rs1379507579 1431 dbSNP
rs938480103 1437 dbSNP
rs1057083995 1441 dbSNP
rs951925606 1479 dbSNP
rs144623058 1482 dbSNP
rs1180724862 1494 dbSNP
rs1359847030 1495 dbSNP
rs370678835 1496 dbSNP
rs1421291632 1498 dbSNP
rs943053106 1501 dbSNP
rs1186558281 1517 dbSNP
rs1423507722 1518 dbSNP
rs1441086072 1519 dbSNP
rs748754627 1519 dbSNP
rs572649402 1525 dbSNP
rs975774215 1532 dbSNP
rs1487323349 1546 dbSNP
rs1263124699 1550 dbSNP
rs11220176 1560 dbSNP
rs1006613036 1570 dbSNP
rs949295920 1596 dbSNP
rs1244492261 1597 dbSNP
rs1321991357 1603 dbSNP
rs1381387110 1608 dbSNP
rs1380040775 1618 dbSNP
rs550412202 1622 dbSNP
rs998090409 1636 dbSNP
rs1298268826 1637 dbSNP
rs1030458160 1638 dbSNP
rs770167851 1641 dbSNP
rs1361354186 1647 dbSNP
rs1042253999 1652 dbSNP
rs1448865039 1672 dbSNP
rs1369295606 1673 dbSNP
rs903384237 1678 dbSNP
rs1476886605 1679 dbSNP
rs1380667947 1684 dbSNP
rs567344136 1684 dbSNP
rs936244239 1686 dbSNP
rs138368921 1691 dbSNP
rs1489585943 1692 dbSNP
rs894732706 1696 dbSNP
rs1013300343 1701 dbSNP
rs1045744018 1704 dbSNP
rs907259154 1716 dbSNP
rs993621795 1717 dbSNP
rs568382140 1722 dbSNP
rs1026141402 1729 dbSNP
rs1242658815 1732 dbSNP
rs951896323 1733 dbSNP
rs553181272 1737 dbSNP
rs1266848410 1742 dbSNP
rs1352764643 1743 dbSNP
rs1316906472 1744 dbSNP
rs1278328639 1749 dbSNP
rs180885007 1751 dbSNP
rs1280681048 1752 dbSNP
rs1010459027 1753 dbSNP
rs1442876902 1758 dbSNP
rs1269270365 1763 dbSNP
rs1017491515 1770 dbSNP
rs964665283 1783 dbSNP
rs1387154327 1797 dbSNP
rs1392537814 1801 dbSNP
rs1208822841 1804 dbSNP
rs1296239259 1806 dbSNP
rs976124566 1808 dbSNP
rs968685585 1812 dbSNP
rs538949609 1817 dbSNP
rs1449106730 1819 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Hela
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1048187. RNA binding protein: AGO2. Condition:Hela_AGO2_CLIP_control ...

- Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al., 2013, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uguuuggUGUCACACGACGAc 5'
                 |:|  |||||||| 
Target 5' cuggugaAUAUAGUGCUGCUa 3'
 		5 - 25
Article - Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al.
- Cell, 2013
The induction of pluripotency or trans-differentiation of one cell type to another can be accomplished with cell-lineage-specific transcription factors. Here, we report that repression of a single RNA binding polypyrimidine-tract-binding (PTB) protein, which occurs during normal brain development via the action of miR-124, is sufficient to induce trans-differentiation of fibroblasts into functional neurons. Besides its traditional role in regulated splicing, we show that PTB has a previously undocumented function in the regulation of microRNA functions, suppressing or enhancing microRNA targeting by competitive binding on target mRNA or altering local RNA secondary structure. A key event during neuronal induction is the relief of PTB-mediated blockage of microRNA action on multiple components of the REST complex, thereby derepressing a large array of neuronal genes, including miR-124 and multiple neuronal-specific transcription factors, in nonneuronal cells. This converts a negative feedback loop to a positive one to elicit cellular reprogramming to the neuronal lineage.
LinkOut: [PMID: 23313552]
CLIP-seq Support 1 for dataset GSM1048187
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Hela / Hela_AGO2_CLIP_control
Location of target site ENST00000534070.1 | 3UTR | AAUCCUGGUGAAUAUAGUGCUGCUAUGUUGACAUUAUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23313552 / GSE42701
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE19536 Breast cancer -0.365 9.4e-5 -0.356 1.4e-4 100 Click to see details
GSE21687 Ependynoma primary tumors -0.364 1.6e-3 -0.318 5.2e-3 64 Click to see details
GSE19783 ER+ ER+ breast cancer -0.601 2.5e-3 -0.580 3.7e-3 20 Click to see details
GSE19783 ER- ER- breast cancer -0.303 3.3e-3 -0.304 3.2e-3 79 Click to see details
GSE42095 Differentiated embryonic stem cells -0.516 5.9e-3 -0.230 1.5e-1 23 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.393 4.3e-2 0.478 1.7e-2 20 Click to see details
GSE38226 Liver fibrosis -0.362 5.3e-2 -0.404 3.5e-2 21 Click to see details
GSE27834 Pluripotent stem cells 0.413 5.6e-2 0.588 8.3e-3 16 Click to see details
GSE28544 Breast cancer -0.257 1.1e-1 -0.089 3.4e-1 24 Click to see details
GSE14794 Lymphoblastoid cells 0.128 1.1e-1 0.201 2.9e-2 90 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.208 1.6e-1 0.364 3.7e-2 25 Click to see details
GSE21849 B cell lymphoma 0.131 2.5e-1 0.413 1.3e-2 29 Click to see details
GSE17306 Multiple myeloma 0.078 3.0e-1 0.337 8.9e-3 49 Click to see details
GSE35602 Colorectal cancer stromal tissue -0.102 3.1e-1 -0.112 3.0e-1 25 Click to see details
GSE19350 CNS germ cell tumors -0.122 3.5e-1 0.105 3.7e-1 12 Click to see details
GSE26953 Aortic valvular endothelial cells -0.066 3.8e-1 -0.137 2.6e-1 24 Click to see details
GSE28260 Renal cortex and medulla -0.074 4.1e-1 0.044 4.4e-1 13 Click to see details
GSE17498 Multiple myeloma 0.032 4.2e-1 -0.109 2.5e-1 40 Click to see details
GSE21032 Prostate cancer 0.013 4.5e-1 0.026 4.1e-1 83 Click to see details
GSE32688 Pancreatic cancer -0.004 4.9e-1 -0.102 2.9e-1 32 Click to see details
GSE32688 Pancreatic cancer -0.004 4.9e-1 -0.102 2.9e-1 32 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
LUSC -0.482 0 -0.452 0 38 Click to see details
KIRC -0.276 0.01 -0.269 0.01 68 Click to see details
COAD -0.586 0.06 -0.690 0.03 8 Click to see details
PCPG -0.938 0.11 -0.500 0.33 3 Click to see details
THCA -0.127 0.17 -0.189 0.08 59 Click to see details
PAAD -0.657 0.17 -0.800 0.1 4 Click to see details
CHOL -0.348 0.18 -0.117 0.38 9 Click to see details
BRCA 0.094 0.2 0.055 0.31 84 Click to see details
HNSC -0.12 0.22 -0.147 0.18 42 Click to see details
UCEC -0.182 0.23 -0.198 0.21 19 Click to see details
CESC 0.725 0.24 1.000 0.5 3 Click to see details
PRAD 0.088 0.27 0.246 0.04 50 Click to see details
LUAD 0.114 0.36 0.154 0.32 12 Click to see details
ESCA 0.112 0.37 0.209 0.27 11 Click to see details
BLCA 0.056 0.41 0.020 0.47 18 Click to see details
LIHC -0.029 0.42 -0.049 0.37 49 Click to see details
STAD 0.035 0.42 0.052 0.39 32 Click to see details
KICH -0.027 0.45 -0.135 0.26 25 Click to see details
KIRP 0.019 0.46 -0.004 0.49 32 Click to see details
KIRP 0.019 0.46 -0.004 0.49 32 Click to see details
KIRP 0.019 0.46 -0.004 0.49 32 Click to see details
437 hsa-miR-497-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT006078 RAF1 Raf-1 proto-oncogene, serine/threonine kinase 3 1
MIRT006079 RUNX2 runt related transcription factor 2 3 1
MIRT006785 IGF1R insulin like growth factor 1 receptor 3 3
MIRT007165 MAP2K1 mitogen-activated protein kinase kinase 1 3 1
MIRT041183 EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1 1
MIRT041184 TCEA1 transcription elongation factor A1 1 1
MIRT041185 HIST1H3H histone cluster 1 H3 family member h 1 1
MIRT041186 ALDH9A1 aldehyde dehydrogenase 9 family member A1 1 1
MIRT041187 DESI2 desumoylating isopeptidase 2 1 1
MIRT041188 HIST2H3A histone cluster 2 H3 family member a 1 1
MIRT041189 PANK2 pantothenate kinase 2 1 1
MIRT041190 ATXN7L3B ataxin 7 like 3B 2 5
MIRT041191 BRD1 bromodomain containing 1 1 1
MIRT053046 WEE1 WEE1 G2 checkpoint kinase 5 5
MIRT053193 DICER1 dicer 1, ribonuclease III 2 1
MIRT053195 HDGF heparin binding growth factor 5 5
MIRT053471 BCL2 BCL2, apoptosis regulator 4 1
MIRT053773 EIF4E eukaryotic translation initiation factor 4E 3 1
MIRT054419 BIRC5 baculoviral IAP repeat containing 5 2 1
MIRT054420 WNT7A Wnt family member 7A 2 1
MIRT054756 SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2 1
MIRT054859 CHEK1 checkpoint kinase 1 5 3
MIRT055428 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 10
MIRT055819 PLEKHA1 pleckstrin homology domain containing A1 2 2
MIRT057519 CEP55 centrosomal protein 55 2 8
MIRT057739 ZDHHC16 zinc finger DHHC-type containing 16 2 2
MIRT060581 CCND1 cyclin D1 2 2
MIRT061010 C1ORF21 chromosome 1 open reading frame 21 2 6
MIRT061251 AMOTL1 angiomotin like 1 2 12
MIRT064690 CCND2 cyclin D2 2 4
MIRT065721 TARBP2 TARBP2, RISC loading complex RNA binding subunit 2 4
MIRT066299 MTFR1L mitochondrial fission regulator 1 like 2 2
MIRT066317 USP15 ubiquitin specific peptidase 15 2 2
MIRT071213 FCF1 FCF1, rRNA-processing protein 2 2
MIRT072827 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2 4
MIRT074535 PAGR1 PAXIP1 associated glutamate rich protein 1 2 4
MIRT075257 SNTB2 syntrophin beta 2 2 4
MIRT075279 VPS4A vacuolar protein sorting 4 homolog A 2 8
MIRT075899 C16ORF72 chromosome 16 open reading frame 72 2 6
MIRT076797 GOSR1 golgi SNAP receptor complex member 1 2 2
MIRT078288 RPS6KB1 ribosomal protein S6 kinase B1 2 2
MIRT079660 NAPG NSF attachment protein gamma 2 12
MIRT080017 GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 2 4
MIRT081649 CCNE1 cyclin E1 4 6
MIRT082990 PNPLA6 patatin like phospholipase domain containing 6 2 2
MIRT083271 ZCCHC3 zinc finger CCHC-type containing 3 2 6
MIRT084467 SOWAHC sosondowah ankyrin repeat domain family member C 2 4
MIRT086014 UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 2 2
MIRT087429 ZNRF3 zinc and ring finger 3 2 2
MIRT087560 YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta 2 2
MIRT089113 B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 2 4
MIRT089213 ACTR2 ARP2 actin related protein 2 homolog 2 2
MIRT091676 RARB retinoic acid receptor beta 2 6
MIRT093689 PI4K2B phosphatidylinositol 4-kinase type 2 beta 2 6
MIRT096240 CANX calnexin 2 2
MIRT099637 E2F3 E2F transcription factor 3 2 1
MIRT100212 PPP1R11 protein phosphatase 1 regulatory inhibitor subunit 11 2 2
MIRT100370 HSPA1B heat shock protein family A (Hsp70) member 1B 2 6
MIRT100573 PIM1 Pim-1 proto-oncogene, serine/threonine kinase 2 2
MIRT100742 VEGFA vascular endothelial growth factor A 2 12
MIRT100901 CD2AP CD2 associated protein 2 2
MIRT102442 CALU calumenin 2 2
MIRT102637 UBN2 ubinuclein 2 2 10
MIRT102976 EN2 engrailed homeobox 2 2 6
MIRT103098 MAFK MAF bZIP transcription factor K 2 4
MIRT103860 FOXK1 forkhead box K1 2 2
MIRT104021 USP42 ubiquitin specific peptidase 42 2 6
MIRT104237 DMTF1 cyclin D binding myb like transcription factor 1 2 2
MIRT106303 ZFHX4 zinc finger homeobox 4 2 6
MIRT106738 RAD23B RAD23 homolog B, nucleotide excision repair protein 2 2
MIRT107223 ZBTB34 zinc finger and BTB domain containing 34 2 2
MIRT107690 RECK reversion inducing cysteine rich protein with kazal motifs 2 2
MIRT109246 ZNF275 zinc finger protein 275 2 2
MIRT110059 OGT O-linked N-acetylglucosamine (GlcNAc) transferase 2 6
MIRT112977 LUZP1 leucine zipper protein 1 2 6
MIRT114931 CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 2 2
MIRT117661 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT120685 PAK2 p21 (RAC1) activated kinase 2 2 2
MIRT127741 ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2 2
MIRT133779 SKI SKI proto-oncogene 2 2
MIRT140154 SPRED1 sprouty related EVH1 domain containing 1 2 2
MIRT140830 SMAD3 SMAD family member 3 1 1
MIRT142250 DCTN5 dynactin subunit 5 2 8
MIRT152289 TNFSF9 TNF superfamily member 9 2 2
MIRT154056 RASSF2 Ras association domain family member 2 2 2
MIRT156471 ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) 2 2
MIRT158534 TNRC6B trinucleotide repeat containing 6B 2 4
MIRT165184 GRAMD3 GRAM domain containing 2B 2 2
MIRT165908 CREBRF CREB3 regulatory factor 2 2
MIRT175238 PSAT1 phosphoserine aminotransferase 1 2 6
MIRT179015 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 2
MIRT180915 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 8
MIRT186376 PNRC2 proline rich nuclear receptor coactivator 2 2 2
MIRT189765 CDADC1 cytidine and dCMP deaminase domain containing 1 2 2
MIRT189966 AGO4 argonaute 4, RISC catalytic component 2 2
MIRT190189 GPR180 G protein-coupled receptor 180 2 6
MIRT191461 PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A 2 2
MIRT191630 SLC39A9 solute carrier family 39 member 9 2 6
MIRT194244 FAM103A1 family with sequence similarity 103 member A1 2 6
MIRT194910 RBBP6 RB binding protein 6, ubiquitin ligase 2 8
MIRT196458 TAOK1 TAO kinase 1 2 2
MIRT201461 SNRPB2 small nuclear ribonucleoprotein polypeptide B2 2 8
MIRT204598 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 8
MIRT204629 MOB4 MOB family member 4, phocein 2 8
MIRT204745 BZW1 basic leucine zipper and W2 domains 1 2 12
MIRT206024 NUP50 nucleoporin 50 2 6
MIRT211203 FGF2 fibroblast growth factor 2 2 4
MIRT211318 HSPA4L heat shock protein family A (Hsp70) member 4 like 3 5
MIRT212612 RBPJ recombination signal binding protein for immunoglobulin kappa J region 2 8
MIRT217748 TBPL1 TATA-box binding protein like 1 2 2
MIRT223696 FZD6 frizzled class receptor 6 4 6
MIRT224970 BAG4 BCL2 associated athanogene 4 2 2
MIRT229352 ZNF449 zinc finger protein 449 2 2
MIRT229865 YIPF6 Yip1 domain family member 6 2 2
MIRT234347 MSL1 male specific lethal 1 homolog 2 8
MIRT247242 ELK4 ELK4, ETS transcription factor 2 4
MIRT247372 GABARAPL1 GABA type A receptor associated protein like 1 2 6
MIRT249454 ZNF691 zinc finger protein 691 2 4
MIRT251498 DYNLL2 dynein light chain LC8-type 2 2 4
MIRT255340 SRPRB SRP receptor beta subunit 2 4
MIRT256312 CDC42SE2 CDC42 small effector 2 2 2
MIRT258415 WIPI2 WD repeat domain, phosphoinositide interacting 2 2 2
MIRT265062 TBRG1 transforming growth factor beta regulator 1 2 2
MIRT267533 C1ORF226 chromosome 1 open reading frame 226 2 2
MIRT270557 SETD1B SET domain containing 1B 2 2
MIRT273670 HOXC8 homeobox C8 2 2
MIRT274746 RAB3IP RAB3A interacting protein 2 2
MIRT277510 PPP2R5C protein phosphatase 2 regulatory subunit B'gamma 2 4
MIRT282539 SLCO3A1 solute carrier organic anion transporter family member 3A1 2 2
MIRT289636 CBX2 chromobox 2 2 2
MIRT294288 ZFP28 ZFP28 zinc finger protein 2 2
MIRT295816 CHMP4B charged multivesicular body protein 4B 2 2
MIRT297783 GABPA GA binding protein transcription factor alpha subunit 2 4
MIRT300112 STRADB STE20-related kinase adaptor beta 2 2
MIRT300999 MTMR3 myotubularin related protein 3 2 2
MIRT302620 CRIM1 cysteine rich transmembrane BMP regulator 1 2 6
MIRT302830 SOCS5 suppressor of cytokine signaling 5 2 2
MIRT307146 CTDSPL CTD small phosphatase like 2 4
MIRT313680 ITGA2 integrin subunit alpha 2 2 2
MIRT314056 PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 2 8
MIRT317726 PPIL1 peptidylprolyl isomerase like 1 2 6
MIRT319336 CAPZA2 capping actin protein of muscle Z-line alpha subunit 2 2 2
MIRT320633 ZNRF2 zinc and ring finger 2 2 2
MIRT326307 OCRL OCRL, inositol polyphosphate-5-phosphatase 2 2
MIRT327969 CHIC1 cysteine rich hydrophobic domain 1 2 6
MIRT367270 CRKL CRK like proto-oncogene, adaptor protein 2 2
MIRT437794 BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 2 1
MIRT437795 CDK4 cyclin dependent kinase 4 2 1
MIRT437796 CCND3 cyclin D3 2 1
MIRT437797 CDC25A cell division cycle 25A 4 3
MIRT443810 SIDT2 SID1 transmembrane family member 2 2 2
MIRT446503 ASCC1 activating signal cointegrator 1 complex subunit 1 2 2
MIRT447773 DMRT2 doublesex and mab-3 related transcription factor 2 2 2
MIRT448442 TLL1 tolloid like 1 2 2
MIRT449185 LUC7L3 LUC7 like 3 pre-mRNA splicing factor 2 2
MIRT451834 ALDH3B1 aldehyde dehydrogenase 3 family member B1 2 2
MIRT453283 EFTUD2 elongation factor Tu GTP binding domain containing 2 2 2
MIRT453749 CSNK1E casein kinase 1 epsilon 2 2
MIRT454965 TPM2 tropomyosin 2 2 2
MIRT456862 ZNF460 zinc finger protein 460 2 10
MIRT460219 FGFR4 fibroblast growth factor receptor 4 2 2
MIRT460433 DOCK11 dedicator of cytokinesis 11 2 2
MIRT461559 ACTR3B ARP3 actin related protein 3 homolog B 2 2
MIRT463165 ZNF367 zinc finger protein 367 2 10
MIRT464665 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 8
MIRT464749 UBE2Q1 ubiquitin conjugating enzyme E2 Q1 2 2
MIRT465161 TSC22D2 TSC22 domain family member 2 2 2
MIRT465565 TOB2 transducer of ERBB2, 2 2 2
MIRT465929 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 8
MIRT466012 TMEM189 transmembrane protein 189 2 8
MIRT466293 TM4SF1 transmembrane 4 L six family member 1 2 2
MIRT466432 TFAP2A transcription factor AP-2 alpha 2 8
MIRT466922 STK38 serine/threonine kinase 38 2 10
MIRT466997 SSRP1 structure specific recognition protein 1 2 4
MIRT468053 SIK1 salt inducible kinase 1 2 2
MIRT468146 SH3BP4 SH3 domain binding protein 4 2 2
MIRT468679 SEC24A SEC24 homolog A, COPII coat complex component 2 4
MIRT469085 RNF168 ring finger protein 168 2 2
MIRT469410 REL REL proto-oncogene, NF-kB subunit 2 6
MIRT471034 PISD phosphatidylserine decarboxylase 2 10
MIRT471491 PDE4D phosphodiesterase 4D 2 4
MIRT471951 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT472267 NFIC nuclear factor I C 2 2
MIRT472662 NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 2 4
MIRT474315 LAMC1 laminin subunit gamma 1 2 2
MIRT474833 KIAA0226 RUN and cysteine rich domain containing beclin 1 interacting protein 2 2
MIRT475064 IVNS1ABP influenza virus NS1A binding protein 2 6
MIRT475125 IPPK inositol-pentakisphosphate 2-kinase 2 2
MIRT475537 HOXA3 homeobox A3 2 8
MIRT475715 HEYL hes related family bHLH transcription factor with YRPW motif-like 2 2
MIRT476255 GNB1 G protein subunit beta 1 2 6
MIRT476272 GNAL G protein subunit alpha L 2 6
MIRT476695 FURIN furin, paired basic amino acid cleaving enzyme 2 2
MIRT477560 EIF1AX eukaryotic translation initiation factor 1A, X-linked 2 8
MIRT477844 DYRK3 dual specificity tyrosine phosphorylation regulated kinase 3 2 2
MIRT478907 CPSF7 cleavage and polyadenylation specific factor 7 2 6
MIRT479455 CDK6 cyclin dependent kinase 6 2 2
MIRT479987 CARD10 caspase recruitment domain family member 10 2 2
MIRT481182 AVL9 AVL9 cell migration associated 2 6
MIRT482114 AKT3 AKT serine/threonine kinase 3 2 4
MIRT482374 AGO2 argonaute 2, RISC catalytic component 2 2
MIRT482554 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 10
MIRT482577 ABHD2 abhydrolase domain containing 2 2 2
MIRT484773 ABCC6 ATP binding cassette subfamily C member 6 2 4
MIRT485219 PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha 2 8
MIRT487389 C10orf54 V-set immunoregulatory receptor 2 2
MIRT492710 PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 2 2
MIRT494351 CASKIN1 CASK interacting protein 1 2 2
MIRT495142 ZNRF1 zinc and ring finger 1 2 2
MIRT496014 CD180 CD180 molecule 2 2
MIRT497771 KIAA0895 KIAA0895 2 2
MIRT498979 ORC4 origin recognition complex subunit 4 2 8
MIRT499451 ODF2L outer dense fiber of sperm tails 2 like 2 8
MIRT499615 DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 2 8
MIRT500092 L2HGDH L-2-hydroxyglutarate dehydrogenase 2 8
MIRT500325 ZNF622 zinc finger protein 622 2 8
MIRT500419 ZMAT3 zinc finger matrin-type 3 2 4
MIRT500575 USP53 ubiquitin specific peptidase 53 2 2
MIRT500859 SYPL1 synaptophysin like 1 2 8
MIRT500937 SRPR SRP receptor alpha subunit 2 6
MIRT500955 SREK1 splicing regulatory glutamic acid and lysine rich protein 1 2 8
MIRT501087 SMAD7 SMAD family member 7 2 8
MIRT501501 PRICKLE2 prickle planar cell polarity protein 2 2 2
MIRT502041 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 2
MIRT502147 KIF5B kinesin family member 5B 2 8
MIRT502497 FAM122B family with sequence similarity 122B 2 8
MIRT502573 E2F7 E2F transcription factor 7 2 10
MIRT502645 DDX3X DEAD-box helicase 3, X-linked 2 8
MIRT502918 CDCA4 cell division cycle associated 4 2 8
MIRT502946 CDC37L1 cell division cycle 37 like 1 2 8
MIRT503142 ATG9A autophagy related 9A 2 6
MIRT504333 ASGR2 asialoglycoprotein receptor 2 2 6
MIRT504535 ZNF620 zinc finger protein 620 2 6
MIRT504851 HAUS3 HAUS augmin like complex subunit 3 2 6
MIRT505113 YTHDC1 YTH domain containing 1 2 6
MIRT505345 TMEM245 transmembrane protein 245 2 6
MIRT505395 TMEM100 transmembrane protein 100 2 2
MIRT505501 SRSF1 serine and arginine rich splicing factor 1 2 6
MIRT505550 SNX16 sorting nexin 16 2 6
MIRT505688 SESTD1 SEC14 and spectrin domain containing 1 2 6
MIRT505907 RIMS3 regulating synaptic membrane exocytosis 3 2 6
MIRT505925 RCAN3 RCAN family member 3 2 4
MIRT506107 PPIG peptidylprolyl isomerase G 2 6
MIRT506136 PLRG1 pleiotropic regulator 1 2 4
MIRT506165 PLAG1 PLAG1 zinc finger 2 8
MIRT506190 PHKA1 phosphorylase kinase regulatory subunit alpha 1 2 6
MIRT506485 MYO5A myosin VA 2 6
MIRT506857 KIF23 kinesin family member 23 2 6
MIRT506998 HNRNPDL heterogeneous nuclear ribonucleoprotein D like 2 6
MIRT507822 CDK1 cyclin dependent kinase 1 2 6
MIRT507849 CCNE2 cyclin E2 2 6
MIRT507878 CBX6 chromobox 6 2 2
MIRT508039 AXIN2 axin 2 2 6
MIRT508640 CASK calcium/calmodulin dependent serine protein kinase 2 5
MIRT509363 DMPK DM1 protein kinase 2 11
MIRT509689 ATAD5 ATPase family, AAA domain containing 5 2 4
MIRT510042 AKR1B10 aldo-keto reductase family 1 member B10 2 4
MIRT511846 GPATCH8 G-patch domain containing 8 2 4
MIRT512286 ARHGDIA Rho GDP dissociation inhibitor alpha 2 6
MIRT512641 CPEB3 cytoplasmic polyadenylation element binding protein 3 2 4
MIRT513858 JARID2 jumonji and AT-rich interaction domain containing 2 2 8
MIRT514019 CAMSAP1 calmodulin regulated spectrin associated protein 1 2 4
MIRT514046 ATG14 autophagy related 14 2 2
MIRT518090 TRIM35 tripartite motif containing 35 2 2
MIRT518529 FLCN folliculin 2 6
MIRT518993 NNT nicotinamide nucleotide transhydrogenase 2 4
MIRT521051 SLC2A3 solute carrier family 2 member 3 2 4
MIRT521202 SBNO1 strawberry notch homolog 1 2 6
MIRT521815 POM121C POM121 transmembrane nucleoporin C 2 2
MIRT522099 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 4
MIRT522774 LAMP2 lysosomal associated membrane protein 2 2 6
MIRT537818 EFNB2 ephrin B2 2 4
MIRT539898 RPL14 ribosomal protein L14 2 4
MIRT540842 GNAT1 G protein subunit alpha transducin 1 2 4
MIRT541218 HOXA10 homeobox A10 2 2
MIRT541433 CBX4 chromobox 4 2 2
MIRT542811 PHC3 polyhomeotic homolog 3 2 2
MIRT542838 PDCD1 programmed cell death 1 2 7
MIRT543058 BAZ2A bromodomain adjacent to zinc finger domain 2A 2 2
MIRT543078 APP amyloid beta precursor protein 2 2
MIRT543305 ZNF585B zinc finger protein 585B 2 2
MIRT543407 ANAPC13 anaphase promoting complex subunit 13 2 2
MIRT543524 PRSS21 protease, serine 21 2 2
MIRT543796 RALGAPB Ral GTPase activating protein non-catalytic beta subunit 2 4
MIRT543834 GSG1 germ cell associated 1 2 2
MIRT544570 POLDIP3 DNA polymerase delta interacting protein 3 2 2
MIRT544588 AP5Z1 adaptor related protein complex 5 zeta 1 subunit 2 4
MIRT544911 CLSPN claspin 2 2
MIRT544964 UGT2B4 UDP glucuronosyltransferase family 2 member B4 2 2
MIRT545185 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2 4
MIRT545346 CCDC83 coiled-coil domain containing 83 2 2
MIRT545681 DECR1 2,4-dienoyl-CoA reductase 1 2 2
MIRT545957 ZBTB10 zinc finger and BTB domain containing 10 2 2
MIRT545975 YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta 2 2
MIRT546113 USP48 ubiquitin specific peptidase 48 2 4
MIRT546609 SALL1 spalt like transcription factor 1 2 4
MIRT546620 RUNX1T1 RUNX1 translocation partner 1 2 2
MIRT546635 RTN4 reticulon 4 2 2
MIRT547067 PNISR PNN interacting serine and arginine rich protein 2 2
MIRT547134 PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2 2
MIRT547236 PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 2 4
MIRT547302 NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 2 2
MIRT547408 MKX mohawk homeobox 2 2
MIRT547459 MBD4 methyl-CpG binding domain 4, DNA glycosylase 2 2
MIRT547548 LRRFIP2 LRR binding FLII interacting protein 2 2 4
MIRT547664 KPNA3 karyopherin subunit alpha 3 2 2
MIRT547699 KPNA1 karyopherin subunit alpha 1 2 4
MIRT547969 HIGD1A HIG1 hypoxia inducible domain family member 1A 2 4
MIRT547998 HCFC2 host cell factor C2 2 4
MIRT548014 GRB2 growth factor receptor bound protein 2 2 4
MIRT548225 FKBP1A FK506 binding protein 1A 2 2
MIRT548278 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT548285 FASN fatty acid synthase 5 5
MIRT548730 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT548804 CLIP4 CAP-Gly domain containing linker protein family member 4 2 4
MIRT548944 CDK17 cyclin dependent kinase 17 2 2
MIRT549080 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT549122 C11orf24 chromosome 11 open reading frame 24 2 4
MIRT549279 ASH1L ASH1 like histone lysine methyltransferase 2 2
MIRT549386 AMOT angiomotin 2 2
MIRT550401 SLC29A1 solute carrier family 29 member 1 (Augustine blood group) 2 4
MIRT550465 OSCAR osteoclast associated, immunoglobulin-like receptor 2 4
MIRT550614 MTHFR methylenetetrahydrofolate reductase 2 2
MIRT550822 FAM229B family with sequence similarity 229 member B 2 2
MIRT551378 EPM2AIP1 EPM2A interacting protein 1 2 2
MIRT551616 ZNF267 zinc finger protein 267 2 2
MIRT551736 SSU72 SSU72 homolog, RNA polymerase II CTD phosphatase 2 2
MIRT552034 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT552343 ZNF704 zinc finger protein 704 2 2
MIRT552748 YRDC yrdC N6-threonylcarbamoyltransferase domain containing 2 2
MIRT553438 TPM3 tropomyosin 3 2 2
MIRT553560 TMEM161B transmembrane protein 161B 2 2
MIRT553619 TM7SF3 transmembrane 7 superfamily member 3 2 2
MIRT553771 TAF13 TATA-box binding protein associated factor 13 2 4
MIRT553808 SZRD1 SUZ RNA binding domain containing 1 2 4
MIRT554699 RNF149 ring finger protein 149 2 2
MIRT554961 RACGAP1 Rac GTPase activating protein 1 2 2
MIRT555031 RAB23 RAB23, member RAS oncogene family 2 2
MIRT555144 PTPRD protein tyrosine phosphatase, receptor type D 2 2
MIRT555224 PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 2 4
MIRT555274 PRDM4 PR/SET domain 4 2 2
MIRT555435 PPAP2B phospholipid phosphatase 3 2 2
MIRT556381 LURAP1L leucine rich adaptor protein 1 like 2 2
MIRT556858 KANK1 KN motif and ankyrin repeat domains 1 2 4
MIRT557280 HIST2H2BE histone cluster 2 H2B family member e 2 2
MIRT557479 GPR27 G protein-coupled receptor 27 2 4
MIRT558036 EXT1 exostosin glycosyltransferase 1 2 2
MIRT558512 CYP26B1 cytochrome P450 family 26 subfamily B member 1 2 4
MIRT558588 CREBL2 cAMP responsive element binding protein like 2 2 4
MIRT558659 CNKSR3 CNKSR family member 3 2 2
MIRT559008 CA8 carbonic anhydrase 8 2 2
MIRT559159 BTN3A3 butyrophilin subfamily 3 member A3 2 2
MIRT559530 ARHGAP12 Rho GTPase activating protein 12 2 4
MIRT560851 OSBPL3 oxysterol binding protein like 3 2 2
MIRT561148 KRT33B keratin 33B 2 2
MIRT561399 TUBB2A tubulin beta 2A class IIa 2 2
MIRT561873 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 2
MIRT562026 LANCL1 LanC like 1 2 2
MIRT562203 HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 2 2
MIRT562876 KIAA1456 KIAA1456 2 2
MIRT563085 SLC25A12 solute carrier family 25 member 12 2 2
MIRT563502 DLGAP3 DLG associated protein 3 2 2
MIRT563700 THRAP3 thyroid hormone receptor associated protein 3 2 2
MIRT563844 SMDT1 single-pass membrane protein with aspartate rich tail 1 2 2
MIRT563895 RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2 2
MIRT564331 CCNT1 cyclin T1 2 2
MIRT564477 ZNF391 zinc finger protein 391 2 2
MIRT564551 CCDC80 coiled-coil domain containing 80 2 2
MIRT564837 ZBTB16 zinc finger and BTB domain containing 16 2 2
MIRT564949 XKR7 XK related 7 2 2
MIRT564985 WNK3 WNK lysine deficient protein kinase 3 2 2
MIRT565045 VAV2 vav guanine nucleotide exchange factor 2 2 2
MIRT565395 TGFBR3 transforming growth factor beta receptor 3 2 2
MIRT566118 RASEF RAS and EF-hand domain containing 2 2
MIRT566649 NCKAP1 NCK associated protein 1 2 2
MIRT566830 MAP3K7 mitogen-activated protein kinase kinase kinase 7 2 2
MIRT567022 KLHL15 kelch like family member 15 2 2
MIRT567445 GNG12 G protein subunit gamma 12 2 2
MIRT567476 FZD9 frizzled class receptor 9 2 2
MIRT568020 CMTM4 CKLF like MARVEL transmembrane domain containing 4 2 2
MIRT568148 CCDC88C coiled-coil domain containing 88C 2 2
MIRT568473 ARMC12 armadillo repeat containing 12 2 2
MIRT568577 AHNAK2 AHNAK nucleoprotein 2 2 2
MIRT568620 ACVR2A activin A receptor type 2A 2 2
MIRT570467 TLK1 tousled like kinase 1 2 2
MIRT571118 UBE2H ubiquitin conjugating enzyme E2 H 2 2
MIRT571282 TTLL5 tubulin tyrosine ligase like 5 2 2
MIRT571427 RIF1 replication timing regulatory factor 1 2 2
MIRT571663 SERBP1 SERPINE1 mRNA binding protein 1 2 2
MIRT571827 PHF19 PHD finger protein 19 2 2
MIRT571930 LSM11 LSM11, U7 small nuclear RNA associated 2 2
MIRT574056 PROSC pyridoxal phosphate binding protein 2 2
MIRT574203 CLEC2D C-type lectin domain family 2 member D 2 2
MIRT574540 PDIA6 protein disulfide isomerase family A member 6 2 4
MIRT574593 N4BP1 NEDD4 binding protein 1 2 2
MIRT575881 Cask calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2 4
MIRT575923 Dmpk dystrophia myotonica-protein kinase 2 7
MIRT576101 Pdcd1 programmed cell death 1 2 5
MIRT576592 Npepps aminopeptidase puromycin sensitive 2 2
MIRT614699 TRAK1 trafficking kinesin protein 1 2 2
MIRT616466 ADRA2B adrenoceptor alpha 2B 2 2
MIRT618895 ANKMY1 ankyrin repeat and MYND domain containing 1 2 2
MIRT621497 GPRC5A G protein-coupled receptor class C group 5 member A 2 4
MIRT640537 C3orf36 chromosome 3 open reading frame 36 2 2
MIRT645509 BSPRY B-box and SPRY domain containing 2 2
MIRT646594 ANKRD36 ankyrin repeat domain 36 2 2
MIRT648783 KLHL40 kelch like family member 40 2 2
MIRT655811 NOTCH2 notch 2 2 2
MIRT658792 EIF2B2 eukaryotic translation initiation factor 2B subunit beta 2 2
MIRT659255 CUL3 cullin 3 2 2
MIRT680981 DCAF17 DDB1 and CUL4 associated factor 17 2 2
MIRT682283 RS1 retinoschisin 1 2 2
MIRT682513 GLP2R glucagon like peptide 2 receptor 2 2
MIRT691708 FLOT2 flotillin 2 2 2
MIRT693929 HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2 2 2
MIRT698081 TPM1 tropomyosin 1 2 2
MIRT701505 NEGR1 neuronal growth regulator 1 2 2
MIRT702091 MCFD2 multiple coagulation factor deficiency 2 2 2
MIRT702880 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT713418 SLC35E2B solute carrier family 35 member E2B 2 2
MIRT714437 ARHGAP32 Rho GTPase activating protein 32 2 2
MIRT716431 RAB15 RAB15, member RAS oncogene family 2 2
MIRT717460 ADORA3 adenosine A3 receptor 2 2
MIRT720150 PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 2 2
MIRT725131 SYNRG synergin gamma 2 2
MIRT731965 KCNN4 potassium calcium-activated channel subfamily N member 4 3 1
MIRT733328 KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding) 2 0
MIRT733577 Smurf2 SMAD specific E3 ubiquitin protein ligase 2 3 0
MIRT733856 MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) 4 0
MIRT734386 SMAD2 SMAD family member 2 2 1
MIRT734389 MAPK3 mitogen-activated protein kinase 3 2 1
MIRT734798 BCL2L2 BCL2 like 2 3 0
MIRT735175 CASC9 cancer susceptibility 9 (non-protein coding) 2 0
MIRT736699 AFAP1 actin filament associated protein 1 3 0
MIRT736717 EMX1 empty spiracles homeobox 1 3 0
MIRT737341 LINC00473 long intergenic non-protein coding RNA 473 3 0
MIRT756126 SNHG25 small nucleolar RNA host gene 25 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-497 Bufalin NULL 9547215 Quantitative real-time PCR colorectal cancer HCT116 cells 24375248 2014 up-regulated
miR-497 Diethylstilbestrol approved 448537 Microarray mammosphere-derived epithelial cells (MDEC) 19549897 2009 up-regulated
miR-497 Ethanol NULL 702 Quantitative real-time PCR CIE10 22141737 2012 up-regulated
miR-497 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 up-regulated
miR-497 Reversine NULL 210332 Microarray C2C12 myoblast cells 24513286 2014 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-497 Tamoxifen 2733525 NSC180973 approved sensitive Low Breast Cancer cell line (MCF-7, T47D)
hsa-mir-497 Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-mir-497 Paclitaxel 36314 NSC125973 approved resistant cell line (W1)
hsa-mir-497 Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-mir-497 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-mir-497 Androstenedione+Letrozole sensitive cell line (MCF-7)
hsa-mir-497 Tamoxifen 2733525 NSC180973 approved sensitive cell line (MCF7)
hsa-mir-497 Cisplatin 5460033 NSC119875 approved sensitive cell line (BxPC3)
hsa-miR-497-5p (11E)-11-(4-aminobutylidene)-15,16-dimethoxy-20-methyl-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaen-19-one 45027844 NSC727621 resistant
hsa-miR-497-5p (11E)-15,16-dimethoxy-20-methyl-11-[3-(methylamino)propylidene]-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaen-19-one 45027834 NSC727048 resistant
hsa-miR-497-5p (1R,12S)-20-[2-(dimethylamino)ethyl]-15,16-dimethoxy-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-2,4(8),9,13,15,17-hexaene-11,19-dione 45027831 NSC726770 resistant
hsa-miR-497-5p (1r,2s,4s,8r,9s,10r,14r,15s)-9-hydroxy-2,14-diiodo-1,10,14-trimethyl-5-methylidene-7,18-dioxatricyclo[13.2.1.04,8]octadecan-6-one 6712557 NSC697264 resistant
hsa-miR-497-5p (1Z)-2-anilino-N-[(5-carbamoyl-1H-imidazol-4-yl)amino]-2-oxoethanimidoyl cyanide 5466279 NSC683605 resistant
hsa-miR-497-5p (2E,5Z)-2-[(5-acetyl-4-methyl-1,3-thiazol-2-yl)hydrazinylidene]-5-[(2-methoxyphenyl)methylidene]-1,3-thiazolidin-4-one 135472679 NSC658292 sensitive
hsa-miR-497-5p (2R)-2-(1H-benzimidazol-2-yl)-2-(2-chloro-6-methylpyrimidin-4-yl)acetonitrile 390694 NSC688326 resistant
hsa-miR-497-5p (2s,3s,7as)-3-hydroxy-2-[(e)-prop-1-enyl]-2,3,7,7a-tetrahydrofuro[3,4-b]pyran-5-one 24202877 NSC726146 resistant
hsa-miR-497-5p (3-sulfanylidene-5,6-dihydroimidazo[2,1-c][1,2,4]thiadiazol-7-yl) 2-[[4-(trifluoromethoxy)phenyl]sulfonylamino]-4,5-dihydroimidazole-1-carbodithioate 24205510 NSC736065 sensitive
hsa-miR-497-5p (3e)-3-[(2-chloro-5-methoxy-1h-indol-3-yl)methylidene]-1-phenylindol-2-one 5471475 NSC711615 sensitive
hsa-miR-497-5p (3R,5R,8R,9S,10S,13R,14S,17R)-17-[(2R)-4-(4,5-dihydro-1H-imidazol-2-yl)butan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 391085 NSC689620 resistant
hsa-miR-497-5p (3z)-6,7-dichloro-3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-1h-indol-2-one 45486324 NSC748498 sensitive
hsa-miR-497-5p (4-butanoyloxythieno[2,3-f][1]benzothiol-8-yl) butanoate 388304 NSC682994 sensitive
hsa-miR-497-5p (4-chlorophenyl) 3-methyl-5-nitroimidazole-4-sulfonate 236063 NSC38086 resistant
hsa-miR-497-5p (4aS,4bR,10bS,12aS)-2-butyl-12a-methyl-8-(2-pyrrolidin-1-ylethoxy)-4,4a,4b,5,6,10b,11,12-octahydronaphtho[2,1-f]isoquinoline-1,3-dione 383426 NSC671765 resistant
hsa-miR-497-5p (4e)-2-(2-hydroxybenzoyl)-5-methyl-4-[(3,4,5-trimethoxyphenyl)methylene]pyrazol-3-one 5467421 NSC652182 sensitive
hsa-miR-497-5p (4z)-4-[[4-(dimethylamino)phenyl]methylidene]-1-methyl-2-phenylpyrazolo[1,5-a]indol-1-ium-6-ol;trifluoromethanesulfonate 5469862 NSC693573 sensitive
hsa-miR-497-5p (7-acetamido-2-acetyloxy-1-methoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-3-yl) acetate 435732 NSC374980 sensitive
hsa-miR-497-5p (e)-1-(benzenesulfonyl)-3-(2-phenyl-1h-indol-3-yl)prop-2-en-1-one 54613416 NSC749193 sensitive
hsa-miR-497-5p (e)-1-[3-[(4,6-dianilino-1,3,5-triazin-2-yl)amino]phenyl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one 45028636 NSC743530 sensitive
hsa-miR-497-5p (E)-1-[3,5-bis[(dimethylamino)methyl]-4-hydroxyphenyl]-3-(4-nitrophenyl)prop-2-en-1-one 5838541 NSC681129 resistant
hsa-miR-497-5p (e)-1-[4-[[4-(4-chloroanilino)-6-(4-fluoroanilino)-1,3,5-triazin-2-yl]amino]phenyl]-3-[4-(dimethylamino)phenyl]prop-2-en-1-one 45028715 NSC743884 sensitive
hsa-miR-497-5p (e)-1-[4-[[4,6-bis(4-fluoroanilino)-1,3,5-triazin-2-yl]amino]phenyl]-3-(furan-2-yl)prop-2-en-1-one 24205907 NSC737226 sensitive
hsa-miR-497-5p (E)-3-(3,4-dihydroxyphenyl)-N-[(13S)-3-methoxy-13-methyl-8,9,11,12,14,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]prop-2-enamide 24205536 NSC736118 resistant
hsa-miR-497-5p (Z)-(4-butoxycarbonylpiperazin-1-yl)-(2,4-dinitrophenoxy)imino-oxidoazanium 11495269 NSC731701 resistant
hsa-miR-497-5p (Z)-2-amino-3-[[4-[2-(methoxymethyl)pyrrolidin-1-yl]phenyl]methylideneamino]but-2-enedinitrile 24206055 NSC737799 resistant
hsa-miR-497-5p (Z)-3-amino-1-(5-amino-3-phenylpyrazol-1-yl)-3-phenylprop-2-en-1-one 21825201 NSC749518 sensitive
hsa-miR-497-5p [(3S,8R,9S,10R,13S,14S,16E,17S)-17-acetyloxy-16-[[3-methoxy-4-(2-piperidin-1-ylethoxy)phenyl]methylidene]-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,17-dodecahydrocyclopenta[a]phenanthren-3-yl] acetate 24204032 NSC730473 resistant
hsa-miR-497-5p [(8R,9S,13S,14S)-2-ethoxy-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] [(8S,9R,13R,14R)-2-ethoxy-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] sulfite;ethyl acetate 389907 NSC686560 sensitive
hsa-miR-497-5p [1-(4-butylphenyl)-2,5-dimethyl-4-(methylcarbamoyloxymethyl)pyrrol-3-yl]methyl N-methylcarbamate 321869 NSC276361 resistant
hsa-miR-497-5p [1-[(2-bromo-5-hydroxy-4-methoxyphenyl)methyl]spiro[1,3,4,5,7,8-hexahydroisoquinoline-6,2'-1,3-dioxolane]-2-yl]-cyclobutylmethanone 401792 NSC715522 sensitive
hsa-miR-497-5p [10-[2-(diethylamino)ethylamino]-8-oxo-1,14,15-triazatetracyclo[7.6.1.02,7.013,16]hexadeca-2(7),3,5,9,11,13(16),14-heptaen-5-yl] acetate 439026 NSC699152 resistant
hsa-miR-497-5p [3-(4-fluorophenyl)-8,9-dimethyl-2-oxo-5H-pyrano[3,2-c]chromen-5-yl] acetate 45113107 NSC747825 sensitive
hsa-miR-497-5p [3,4,5-tris(2,2-dimethylpropanoyloxy)-6-[(2S)-4-hydroxybutan-2-yl]oxyoxan-2-yl]methyl 2,2-dimethylpropanoate 389870 NSC686498 resistant
hsa-miR-497-5p [6-[(E)-(carbamothioylhydrazinylidene)methyl]pyridin-3-yl] acetate 9555726 NSC144055 sensitive
hsa-miR-497-5p 1-(4-methoxyphenyl)-3-[(z)-1-[6-[(z)-n-[(4-methoxyphenyl)carbamothioylamino]-c-methylcarbonimidoyl]pyridin-2-yl]ethylideneamino]thiourea 6375828 NSC668486 resistant
hsa-miR-497-5p 1-(4,8-dioxothieno[2,3-f][1]benzothiol-2-yl)ethyl acetate 388025 NSC682450 sensitive
hsa-miR-497-5p 1-[(z)-(4-methoxyphenyl)methylideneamino]-3-naphthalen-1-ylurea 5914027 NSC680934 sensitive
hsa-miR-497-5p 1-[(z)-(5-chloro-2-hydroxyphenyl)methylideneamino]-3-[(e)-(5-chloro-2-hydroxyphenyl)methylideneamino]thiourea 135460243 NSC65022 resistant
hsa-miR-497-5p 1-[(z)-1-[6-[(z)-c-methyl-n-(phenylcarbamothioylamino)carbonimidoyl]pyridin-2-yl]ethylideneamino]-3-phenylthiourea 6374206 NSC668482 resistant
hsa-miR-497-5p 1-[4-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]butyl]-5,10-dihydroxynaphtho[2,3-f]indole-4,11-dione 406508 NSC724635 resistant
hsa-miR-497-5p 1-[5-[[[4-chlorobutyl(methyl)amino]-[(5-nitrofuran-2-yl)methoxy]phosphoryl]oxymethyl]-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione 404846 NSC721390 sensitive
hsa-miR-497-5p 1-[7-methyl-8-(3,4,5-trimethoxyphenyl)-7,8-dihydro-6h-[1,3]dioxolo[4,5-g]chromen-6-yl]piperazine 384846 NSC675364 sensitive
hsa-miR-497-5p 1-[phenyl(2-pyridinyl)methylene]-4-(2-methylphenyl)thiosemicarbazide 6148953 NSC668326 resistant
hsa-miR-497-5p 10,16-bis[2-(dimethylamino)ethyl]-5-hydroxy-1,9,10,16-tetrazapentacyclo[9.6.2.02,7.08,19.014,18]nonadeca-2(7),3,5,8,11(19),12,14(18)-heptaene-15,17-dione 399631 NSC710548 resistant
hsa-miR-497-5p 15-[2-(dimethylamino)ethyl]-10-[2-(dimethylamino)ethylamino]-5-methoxy-1,15-diazatetracyclo[7.7.1.02,7.013,17]heptadeca-2(7),3,5,9,11,13(17)-hexaene-8,14,16-trione;hydrochloride 392061 NSC691851 resistant
hsa-miR-497-5p 1h-indole, 5-bromo-3-[2-(2-pyridinyl)-4-thiazolyl]- 397551 NSC705871 resistant
hsa-miR-497-5p 2-(2-benzoylbenzimidazol-1-yl)-1-(4-fluorophenyl)ethanone 45029093 NSC745451 sensitive
hsa-miR-497-5p 2-(2-chlorophenyl)-3-[5-(1,2,4-triazol-4-ylmethyl)-1,3,4-oxadiazol-2-yl]-1,3-thiazolidin-4-one 45029357 NSC746513 sensitive
hsa-miR-497-5p 2-(2-hydroxyphenyl)-3-[2-[2-(2-hydroxyphenyl)-4-oxo-1,3-thiazolidin-3-yl]-[1,3]thiazolo[5,4-f][1,3]benzothiazol-6-yl]-1,3-thiazolidin-4-one 398513 NSC708424 sensitive
hsa-miR-497-5p 2-(3-ethoxy-4-hydroxyphenyl)-3-[2-[2-(3-ethoxy-4-hydroxyphenyl)-4-oxo-1,3-thiazolidin-3-yl]-[1,3]thiazolo[5,4-f][1,3]benzothiazol-6-yl]-1,3-thiazolidin-4-one 398511 NSC708422 sensitive
hsa-miR-497-5p 2-(3,5-di-tert-butyl-4-methoxybenzyl)cyclopent-4-ene-1,3-dione 403662 NSC718730 resistant
hsa-miR-497-5p 2-(furan-2-yl)-5-phenyl-1h-pyrazolo[1,5-a]pyrimidin-7-one 342597 NSC379651 sensitive
hsa-miR-497-5p 2-(hydroxymethyl)-5-[6-(2-propan-2-ylidenehydrazinyl)purin-9-yl]oxolane-3,4-diol 60147745 NSC752330 resistant
hsa-miR-497-5p 2-(hydroxymethyl)-5-[6-[(e)-2-hydroxy-2-phenylethenyl]purin-9-yl]oxolane-3,4-diol 135476744 NSC295272 resistant
hsa-miR-497-5p 2-(naphthalen-2-ylamino)-1,2-diphenylethanone 411561 NSC34924 sensitive
hsa-miR-497-5p 2-[(z)-6-(2-fluorophenyl)hex-3-en-1,5-diynyl]aniline 24204954 NSC733691 sensitive
hsa-miR-497-5p 2-[[1-[[(1r,4s,5r,8s,9r,10s,12r,13r)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]-3-[[(1r,4s,5r,8s,9r,10s,13r)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[ 45027898 NSC735846 resistant
hsa-miR-497-5p 2-[[5-methoxy-2-(4-methoxyphenyl)-1h-indol-3-yl]methylidene]propanedinitrile 44435255 NSC749028 sensitive
hsa-miR-497-5p 2-[[6-[[bis(carboxymethyl)amino]methyl]-4-[2-[4-(2-phenylethynyl)phenyl]ethynyl]pyridin-2-yl]methyl-(carboxymethyl)amino]acetic acid 369524 NSC641379 resistant
hsa-miR-497-5p 2-[2-[(z)-1-benzamido-2-(2-hydroxyphenyl)vinyl]-5-oxo-oxazolidin-4-yl]acetic acid 6477540 NSC686413 sensitive
hsa-miR-497-5p 2-[4-[5-[2,6-dimethoxy-4-[5-(3,4,5-trimethoxyphenyl)-4,5-dihydro-1,2-oxazol-3-yl]phenoxy]pentoxy]-3-methoxyphenyl]-2,3-dihydro-1H-quinazolin-4-one 45029290 NSC746035 sensitive
hsa-miR-497-5p 2-hydroxy-N-[(E)-1-[6-[(E)-N-[(2-hydroxybenzoyl)amino]-C-methylcarbonimidoyl]pyridin-2-yl]ethylideneamino]benzamide 5779747 NSC617573 resistant
hsa-miR-497-5p 2-isonicotinoyl-5-methyl-4-(2-naphthyldiazenyl)-2,4-dihydro-3h-pyrazol-3-one 327703 NSC303769 sensitive
hsa-miR-497-5p 2-methoxy-5,7,8,13,13a,14-hexahydroisoquino[3,2-b][3]benzazepine 392606 NSC693146 resistant
hsa-miR-497-5p 2-methyl-4,4-diphenyl-1,4-benzoxaphosphinin-4-ium;bromide 24199840 NSC346098 sensitive
hsa-miR-497-5p 2-phenyl-6-((1-phenyl-1h-tetraazol-5-yl)oxy)-4h-chromen-4-one 386037 NSC677603 sensitive
hsa-miR-497-5p 2,3-dibenzoyloxy-4-hydroxy-4-oxobutanoate;(2,5-dimethylphenyl)-(4-methylphenyl)-phenylsulfanium 5351228 NSC116693 sensitive
hsa-miR-497-5p 2,3-dimethoxy-5-[(E)-3,7,11,15-tetramethylhexadec-2-enyl]sulfanylcyclohexa-2,5-diene-1,4-dione 5476942 NSC276371 sensitive
hsa-miR-497-5p 2,4-diethoxyestra-1,3,5(10)trien-3,17.beta.-diol 388044 NSC682505 sensitive
hsa-miR-497-5p 2,5,12-trimethyl-[1,4]benzodioxino[3,2-g]isoquinolin-2-ium acetate 388316 NSC683048 sensitive
hsa-miR-497-5p 2,6-bis[1-(3-ethylthioureidoimino)ethyl]pyridine 6393657 NSC668337 resistant
hsa-miR-497-5p 3-(3-fluorophenyl)-n-pyridin-3-yl-2h-pyrazolo[3,4-d][1,3]thiazol-5-amine 60147811 NSC752461 sensitive
hsa-miR-497-5p 3-(3,5-dichlorophenyl)-2-(2-pyridinyl)acrylonitrile 5467799 NSC659323 sensitive
hsa-miR-497-5p 3-(4-bromophenyl)-4-methyl-8-pyrrolidin-1-yl-8H-thieno[2,3-b]pyrrolizin-4-ium;iodide 388536 NSC683517 sensitive
hsa-miR-497-5p 3-(4-chlorophenyl)thieno[2,3-b]pyrrolizin-8-one 388525 NSC683509 sensitive
hsa-miR-497-5p 3-(4-fluorophenyl)-4-(4-methoxyphenyl)-6-(4-pyridyl)pyridin-2-amine 388617 NSC683628 resistant
hsa-miR-497-5p 3-(4-methoxyphenyl)-1-[(e)-2-(2-thienyl)vinyl]pyrazino[1,2-a]benzimidazole 5471218 NSC709480 sensitive
hsa-miR-497-5p 3-(4-methoxyphenyl)-3,3a,4,5-tetrahydro-2h-benzo[g]indazole 21792363 NSC744693 sensitive
hsa-miR-497-5p 3-(4-methoxyphenyl)-4-methyl-8-pyrrolidin-1-yl-8H-thieno[2,3-b]pyrrolizin-4-ium;iodide 388538 NSC683518 sensitive
hsa-miR-497-5p 3-(9-amino-4-methoxy-6-methyl-7,8-dihydro-5h-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6,7-dimethoxy-3h-2-benzofuran-1-one;hydrochloride 45028024 NSC740642 sensitive
hsa-miR-497-5p 3-[(e)-1-(2-hydroxy-4-methoxy-phenyl)ethylideneamino]-1,1-dimethyl-thiourea 135493996 NSC689547 resistant
hsa-miR-497-5p 3-[1-(1,3-benzothiazol-2-yl)-3-chloro-6-methyl-2-oxo-1,7,8-triazaspiro[3.4]oct-6-en-8-yl]benzenesulfonic acid 397240 NSC704657 resistant
hsa-miR-497-5p 3-[4-(6-methoxy-1H-benzimidazol-2-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazole 118624714 NSC761814 sensitive
hsa-miR-497-5p 3-methyl-4-methylsulfanyl-5-phenyl-6h-pyrazolo[3,4-c]pyrazole 135450457 NSC692021 resistant
hsa-miR-497-5p 3-N',5-N'-bis(2-hydroxybenzoyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbohydrazide 377030 NSC658247 sensitive
hsa-miR-497-5p 3-phenacyliden-5-brom-2-indolinon 5351299 NSC294961 resistant
hsa-miR-497-5p 3,25-dioxa-11,14,17,31-tetrazatetracyclo[25.3.1.04,9.019,24]hentriaconta-1(31),4,6,8,10,17,19,21,23,27,29-undecaene 388222 NSC682815 sensitive
hsa-miR-497-5p 3,4-diphenylisoxazolo[3,4-d]pyridazin-7(6h)-one 54613569 NSC749505 sensitive
hsa-miR-497-5p 3,5,12,14-tetrabutyl-7,10-dithia-8,9-diselena-3,5,12,14-tetrazatricyclo[9.3.0.02,6]tetradeca-1(11),2(6)-diene-4,13-diselone 395765 NSC700584 resistant
hsa-miR-497-5p 4-(3-(4-((2,2-dimethylpropanoyl)oxy)phenyl)acryloyl)phenyl pivalate 5468262 NSC666765 sensitive
hsa-miR-497-5p 4-(3h-[1,3]thiazolo[3,4-a]benzimidazol-1-yl)phenyl acetate 384820 NSC675272 sensitive
hsa-miR-497-5p 4-(4-fluorophenyl)-2-[8-[[4-(4-fluorophenyl)-5-propyl-1h-imidazol-2-yl]sulfanyl]octylsulfanyl]-5-propyl-1h-imidazole;methanesulfonic acid 374589 NSC652562 sensitive
hsa-miR-497-5p 4-(dimethylamino)-9-ethyl-16-methyl-4,20-diazapentacyclo[11.7.0.02,6.07,12.014,19]icosa-1(13),14(19),15,17-tetraene-3,5-dione 397883 NSC706739 sensitive
hsa-miR-497-5p 4-[(4-methyl-1,2-oxazol-5-yl)amino]naphthalene-1,2-dione 384244 NSC673785 sensitive
hsa-miR-497-5p 4-[(6-chloro-4h-1,3-benzodioxin-8-yl)methylsulfanyl]pyrrolo[1,2-a]quinoxaline 331156 NSC321491 sensitive
hsa-miR-497-5p 4-[2-(11h-indolo[3,2-c]quinolin-6-ylamino)ethyl]benzene-1,2-diol 24205774 NSC736609 resistant
hsa-miR-497-5p 4-[4-(diethylamino)phenyl]-2-(4-hydroxypiperidin-1-yl)-6-(3,4,5-trimethoxyphenyl)pyridine-3-carbonitrile 60148088 NSC753601 resistant
hsa-miR-497-5p 4-[4,6-bis(methylsulfanyl)pyrazolo[3,4-d]pyrimidin-1-yl]-7-chloroquinoline 24203467 NSC728188 sensitive
hsa-miR-497-5p 4-methoxy-2,6-bis[hydroxy(methyl)amino]-1,3,5-triazine 46191705 NSC749909 resistant
hsa-miR-497-5p 4,4-dibromo-1-(3-bromo-4-methylpentyl)cyclopentene 382925 NSC670802 resistant
hsa-miR-497-5p 4,8-dioxothieno[3,2-f][1]benzothiole-2-carboxylic acid 375906 NSC656243 sensitive
hsa-miR-497-5p 5-[(E)-[(3aR,6S,6aR)-6-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxol-4-ylidene]-(3,4,5-trimethoxyphenyl)methyl]-2-methoxyphenol 54576090 NSC753427 sensitive
hsa-miR-497-5p 5-[(E)-3-[4-(diethylamino)phenyl]prop-2-enylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione 6376062 NSC684567 sensitive
hsa-miR-497-5p 5-amino-3-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6h-triazolo[4,5-d]pyrimidin-7-one 135454027 NSC89822 resistant
hsa-miR-497-5p 5-chroman-6-yl-2-(4-pyridyl)oxazole 380226 NSC665702 sensitive
hsa-miR-497-5p 5-fluoranyl-7-nitro-quinolin-8-ol 260644 NSC92207 resistant
hsa-miR-497-5p 5-methyl-2-{[(2)-3-phenylprop-2-enoyl]amino}benzamide 53329052 NSC748147 sensitive
hsa-miR-497-5p 5-methylphenanthroline 72791 NSC4272 resistant
hsa-miR-497-5p 5-phenyl-2,3-bis(2-thienyl)thiophene 395510 NSC700200 sensitive
hsa-miR-497-5p 6-(1,5-dimethyl-3-oxo-hexyl)-4,8a-dimethyl-1,4a,5,6,7,8-hexahydronaphthalen-2-one 390517 NSC687958 resistant
hsa-miR-497-5p 6-(11-aminoundecyl)indeno[1,2-c]isoquinoline-5,11-dione;hydrochloride 16221323 NSC740510 resistant
hsa-miR-497-5p 6-(4-acetylanilino)-9-methoxyindeno[1,2-c]quinolin-11-one 24205210 NSC734628 sensitive
hsa-miR-497-5p 6-[(2e)-2-(4-fluorophenyl)-2-hydroxyiminoethoxy]-2-phenylchromen-4-one 24203680 NSC729146 sensitive
hsa-miR-497-5p 6-[2-[2-[2-(5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)ethylamino]ethylamino]ethyl]indeno[1,2-c]isoquinoline-5,11-dione;2,2,2-trifluoroacetic acid 45027833 NSC726973 resistant
hsa-miR-497-5p 6-[3-[2-[3-(5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)propylamino]ethylamino]propyl]indeno[1,2-c]isoquinoline-5,11-dione;2,2,2-trifluoroacetic acid 45027830 NSC726767 resistant
hsa-miR-497-5p 6-[3-[3-[3-(5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)propylamino]propylamino]propyl]indeno[1,2-c]isoquinoline-5,11-dione 11520588 NSC727357 resistant
hsa-miR-497-5p 6-benzyl-3,8,9-trimethoxy-11-methyl-6,11-dihydro-5h-indeno[1,2-c]isoquinolin-5-one 373164 NSC649107 sensitive
hsa-miR-497-5p 6-bromochroman-2-one 266737 NSC105509 sensitive
hsa-miR-497-5p 6-butyl-12-methyl-5,6-dihydrobenzimidazolo[2,1-a]isoquinolin-7-ium-3,10-diol;6-butyl-12-methyl-5,6-dihydrobenzimidazolo[2,1-a]isoquinolin-12-ium-3,9-diol;diiodide 403475 NSC718370 sensitive
hsa-miR-497-5p 6,6-dimethyl-2,10-dimethylidene-4,8-dioxadispiro[4.1.47.35]tetradecane-3,9-dione 318804 NSC258625 resistant
hsa-miR-497-5p 7'-but-3-en-2-yl-7'-(3-phenylmethoxypropyl)spiro[1,3-dioxolane-2,2'-3,4,7a,8,9,10-hexahydro-1h-cyclopenta[i]indolizine]-6'-thione 361486 NSC624523 sensitive
hsa-miR-497-5p 7jx 384175 NSC673499 sensitive
hsa-miR-497-5p 8-azadenosine 251928 NSC72961 resistant
hsa-miR-497-5p 9-[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]anilino]-n-(2-hydroxyethyl)acridine-4-carboxamide 384527 NSC674498 resistant
hsa-miR-497-5p A15655 262000 NSC95170 sensitive
hsa-miR-497-5p Abiraterone 132971 NSC749226 approved sensitive
hsa-miR-497-5p Abiraterone 132971 NSC749226 approved sensitive
hsa-miR-497-5p Acetic acid;4-(2-aminocyclohexyl)imino-2-methylbenzo[f][1,3]benzoxazol-9-one 388014 NSC682436 sensitive
hsa-miR-497-5p Aklavin 264889 NSC100290 resistant
hsa-miR-497-5p Alvocidib 5287969 NSC649890 resistant
hsa-miR-497-5p Amonafide 50515 NSC308847 resistant
hsa-miR-497-5p Ao-267/15176074 393944 NSC696916 resistant
hsa-miR-497-5p Arylpurines 24205955 NSC737430 resistant
hsa-miR-497-5p Basic yellow k 7081 NSC13973 resistant
hsa-miR-497-5p Benzyl n-[5-[(2-methylpropan-2-yl)oxycarbonylamino]-6-[2-[[4-[2-[[2-[(2-methylpropan-2-yl)oxycarbonylamino]-6-(phenylmethoxycarbonylamino)hexanoyl]amino]ethylamino]-9,10-dioxoanthracen-1-yl]amino]ethy 438923 NSC684439 sensitive
hsa-miR-497-5p Berberine iodide 72350 NSC150446 sensitive
hsa-miR-497-5p Bindschedler's green 73516 NSC7811 sensitive
hsa-miR-497-5p Butanedioic acid;10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine 5351168 NSC46061 resistant
hsa-miR-497-5p Centaureidin 5315773 NSC106969 sensitive
hsa-miR-497-5p Cinnoline, 4-nitro-, 1-oxide 100397 NSC294846 resistant
hsa-miR-497-5p Destruxin b NSC236580 resistant
hsa-miR-497-5p Diaziridinone, bis(.alpha.,.alpha.-dimethylphenethyl)- 391928 NSC691608 resistant
hsa-miR-497-5p Diethyl 5,10-dioxobenzo[g]quinoxaline-2,3-dicarboxylate 400766 NSC713197 sensitive
hsa-miR-497-5p Diethyl(acetylamino)[(6-nitro-1h-indol-3-yl)methyl]propanedioate 249442 NSC67774 sensitive
hsa-miR-497-5p Dihydrorotenone 243725 NSC53866 sensitive
hsa-miR-497-5p Edelfosine 1392 NSC324368 resistant
hsa-miR-497-5p Ethyl 2-((4-(6-bromo-2-methyl-4-oxo-3(4h)-quinazolinyl)phenyl)hydrazono)-3-oxobutanoate 135494008 NSC691085 sensitive
hsa-miR-497-5p Ethyl 5-amino-4-(3,4-dihydro-2h-1,5-benzodioxepin-7-ylamino)-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxylate 399955 NSC711107 sensitive
hsa-miR-497-5p From combretum caffrum plant 5386397 NSC609397 sensitive
hsa-miR-497-5p Hexadecyl-(2-hydroxyethyl)-(1H-imidazol-5-ylmethyl)-methylazanium;chloride 21144688 NSC265875 resistant
hsa-miR-497-5p Hsdb 8106 16129719 NSC676825 resistant
hsa-miR-497-5p Hx-0835 5471280 NSC710264 sensitive
hsa-miR-497-5p Ilmofosine 55008 NSC601679 resistant
hsa-miR-497-5p Ixabepilone 6445540 NSC747973 sensitive
hsa-miR-497-5p J-400634 385621 NSC676944 resistant
hsa-miR-497-5p Justicidin b 122805 NSC254665 resistant
hsa-miR-497-5p Kikubasaponin 500377 NSC698792 resistant
hsa-miR-497-5p L-cysteine, s-[(4-chlorophenyl)diphenylmethyl]- 275977 NSC123138 sensitive
hsa-miR-497-5p L-lys-l-p-no2phe-l-ala-l-p-no2phenh2 386384 NSC678355 resistant
hsa-miR-497-5p Lomondomycin 135426834 NSC156939 sensitive
hsa-miR-497-5p Massoia lactone 39914 NSC720841 resistant
hsa-miR-497-5p Methyl (1s,10r)-6-methyl-10-nonyl-7,9,12-triazatricyclo[6.3.1.04,12]dodeca-5,8-diene-5-carboxylate 401693 NSC715423 sensitive
hsa-miR-497-5p Methyl (Z)-4,4-dicyano-4-[(3-methoxyphenyl)methylideneamino]but-2-enoate 5470182 NSC698278 resistant
hsa-miR-497-5p Methyl 10-oxo-3,13,23-triazahexacyclo[11.10.1.02,11.04,9.014,19.020,24]tetracosa-1(24),2(11),4,6,8,14,16,18,20,22-decaene-22-carboxylate 45028277 NSC742037 sensitive
hsa-miR-497-5p Methyl 11h-pyrido[2,3-a]carbazole-5-carboxylate 13776879 NSC740203 sensitive
hsa-miR-497-5p Methyl 2-(2,3-dihydro-1H-inden-5-ylmethyl)-1-oxo-3,6,7,8-tetrahydro-as-indacene-2-carboxylate 385670 NSC677016 sensitive
hsa-miR-497-5p Methyl 2-[33,34,35,36-tetrahydroxy-11,19,27-tris(2-methoxy-2-oxoethyl)-7,15,23,31-tetramethyl-3,11,19,27-tetrazapentacyclo[27.3.1.15,9.113,17.121,25]hexatriaconta-1(32),5,7,9(36),13,15,17(35),21(34),2 395595 NSC700325 resistant
hsa-miR-497-5p Methyl 4-[[3-chloro-4-(3-chloro-2-methylanilino)-2,5-dioxopyrrol-1-yl]methyl]benzoate 1179905 NSC732800 resistant
hsa-miR-497-5p Methyl 4-[3-(2-thienyl)quinoxalin-2-yl]oxybenzoate 388002 NSC682365 sensitive
hsa-miR-497-5p Miltefosin c 3599 NSC605583 resistant
hsa-miR-497-5p N'-(2-hydroxy-5-(hydroxy(oxido)amino)benzylidene)-1-piperidinecarbothiohydrazide 135484941 NSC689530 resistant
hsa-miR-497-5p N'-[2-(1,3-benzoxazol-2-ylamino)-6-methylpyrimidin-4-yl]-2-hydroxybenzohydrazide 24205702 NSC736401 resistant
hsa-miR-497-5p N'-[8-(4-hydroxy-3,5-dimethoxyphenyl)-7-methyl-7,8-dihydro-6h-[1,3]dioxolo[4,5-g]chromen-6-yl]-4-methylbenzenesulfonohydrazide 383134 NSC671175 sensitive
hsa-miR-497-5p N'-chloro-4-[2-[2-[4-[(Z)-N'-chlorocarbamimidoyl]phenoxy]ethyl-(4-methylphenyl)sulfonylamino]ethoxy]benzenecarboximidamide 45028721 NSC743909 sensitive
hsa-miR-497-5p N'-decyl-4-[4-[4-(N'-decylcarbamimidoyl)phenyl]piperazin-1-yl]benzenecarboximidamide;hydrochloride 24203698 NSC729166 sensitive
hsa-miR-497-5p N-((2,3-dimethoxy-6-quinoxalinyl)methyl)-3,4,5-trimethoxy-n-(2-propynyl)aniline 394503 NSC698048 sensitive
hsa-miR-497-5p N-(1,3-benzothiazol-2-yl)-2-phenyl-7-(3,4,5-trimethoxyphenyl)pyrazolo[1,5-a]pyrimidine-5-carboxamide 71624130 NSC763635 sensitive
hsa-miR-497-5p N-(3-chloro-1,4-dioxonaphthalen-2-yl)-2-(4-hydroxy-2-oxochromen-3-yl)-2-oxoacetamide 54693275 NSC649811 sensitive
hsa-miR-497-5p N-(3-chloro-1,4-dioxonaphthalen-2-yl)-4-[2-[(3,4-dioxonaphthalen-2-yl)amino]phenyl]-2,4-dioxobutanamide 369475 NSC641245 sensitive
hsa-miR-497-5p N-(7-chloroquinolin-4-yl)-N',N'-diethyl-2-(4-methoxyphenyl)butane-1,4-diamine 223171 NSC13300 resistant
hsa-miR-497-5p N-[(22s)-13-methoxy-18-methylsulfanyl-19-oxo-4,11-diazapentacyclo[12.10.0.03,12.05,10.015,21]tetracosa-1,3,5,7,9,11,13,15,17,20-decaen-22-yl]acetamide 395872 NSC700913 sensitive
hsa-miR-497-5p N-[(e)-[4-(diethylamino)-2-hydroxyphenyl]methylideneamino]-2-[[2-(trifluoromethyl)pyridin-4-yl]amino]benzamide 135968272 NSC747458 resistant
hsa-miR-497-5p N-[(E)-1-pyrimidin-4-ylethylideneamino]-1,3-benzothiazol-2-amine 5351439 NSC693632 resistant
hsa-miR-497-5p N-[(Z)-1-(4-oxo-3,1-benzoxazin-2-yl)-2-phenylethenyl]benzamide 5917766 NSC686428 sensitive
hsa-miR-497-5p N-[2-(1h-indol-3-yl)ethyl]-4-[[[(e)-3-(4-phenylphenyl)prop-2-enoyl]amino]methyl]benzamide 5470491 NSC702137 resistant
hsa-miR-497-5p N-[2-(dimethylamino)ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide 3508054 NSC751342 resistant
hsa-miR-497-5p N-[2-(dimethylamino)ethyl]-4-(furo[3,2-c]quinolin-4-ylamino)benzamide 24204686 NSC732490 resistant
hsa-miR-497-5p N-[2-(dimethylamino)ethyl]-9-fluorophenazine-1-carboxamide;hydrochloride 386521 NSC678925 resistant
hsa-miR-497-5p N-[2-(dimethylamino)ethyl]-9-nitrodibenzo-p-dioxin-1-carboxamide;hydrochloride 370721 NSC644221 resistant
hsa-miR-497-5p N-[2-[[4,5-dihydroxy-2-methyl-6-(7H-purin-6-ylamino)oxan-3-yl]amino]-2-oxoethyl]-14-methylpentadecanamide 4366047 NSC268251 resistant
hsa-miR-497-5p N-[3-(dimethylamino)propyl]-9-oxo-2-thia-11,14-diazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(10),3,5,7,12,14,16-heptaene-13-carboxamide 385059 NSC675988 resistant
hsa-miR-497-5p N,N'-bis[(5E)-5-[(3,4-dihydroxyphenyl)methylidene]-2-(2-hydroxynaphthalen-1-yl)-4-oxo-1,3-thiazolidin-3-yl]decanediamide 5470052 NSC697192 resistant
hsa-miR-497-5p N,N-diethyl-2-[(E)-(3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ylidene)amino]oxyethanamine 6065911 NSC680094 resistant
hsa-miR-497-5p Nabor orange r 135436499 NSC4434 sensitive
hsa-miR-497-5p Naphtho[1,2-b]quinolizinium, 10,13-dimethyl- chloride 20245316 NSC78629 sensitive
hsa-miR-497-5p Naphtho[2,1-b]quinolizinium, 7-methyl- chloride 5351151 NSC28002 sensitive
hsa-miR-497-5p Ncichal_000043 393018 NSC694266 sensitive
hsa-miR-497-5p Neuro_000327 16683203 NSC643859 sensitive
hsa-miR-497-5p Neuro_000347 438571 NSC645835 resistant
hsa-miR-497-5p Nleoexcpikohjb-uhfffaoysa-n 347804 NSC406666 resistant
hsa-miR-497-5p NSC697653 NSC697653 resistant
hsa-miR-497-5p NSC724065 NSC724065 resistant
hsa-miR-497-5p NSC755523 NSC755523 resistant
hsa-miR-497-5p NSC763238 NSC763238 sensitive
hsa-miR-497-5p Octadecylphosphocholine 125219 NSC282880 resistant
hsa-miR-497-5p Octanamide, 2-amino-n-(2,5-dimethyl-1h-pyrrol-1-yl)-2-hexyl- 380384 NSC665899 sensitive
hsa-miR-497-5p Olaparib 23725625 NSC747856 approved sensitive
hsa-miR-497-5p P-fuchsin 11292 NSC10460 sensitive
hsa-miR-497-5p Pan (van) 6825 NSC5332 resistant
hsa-miR-497-5p Paullone analog 44 395169 NSC699471 sensitive
hsa-miR-497-5p Pc 287 239486 NSC44580 resistant
hsa-miR-497-5p Peliomycin (usan) NSC76455 sensitive
hsa-miR-497-5p Perifosine 148177 NSC639966 resistant
hsa-miR-497-5p Phosphonium, triphenylpropenyl-, bromide, (e)- (8ci) 10714966 NSC289922 sensitive
hsa-miR-497-5p Proflavine hcl 197873 NSC605756 resistant
hsa-miR-497-5p Pyrazolanthrone 8515 NSC75890 resistant
hsa-miR-497-5p Questiomycin a 72725 NSC94945 sensitive
hsa-miR-497-5p Replaced cas registry number(s): 66835-31-2 312122 NSC220334 sensitive
hsa-miR-497-5p Reumycin 5351216 NSC99733 resistant
hsa-miR-497-5p Sc-60646 419381 NSC114382 sensitive
hsa-miR-497-5p Sodium;3-hydroxy-4-[(1-hydroxynaphthalen-2-yl)diazenyl]-8-nitronaphthalene-1-sulfonate 135488931 NSC85561 resistant
hsa-miR-497-5p Sr16388 54612678 NSC745098 sensitive
hsa-miR-497-5p Stereoisomer of nsc 674067-p 384359 NSC674066 resistant
hsa-miR-497-5p Stk673166 NSC717468 sensitive
hsa-miR-497-5p Stl437902 228624 NSC21683 sensitive
hsa-miR-497-5p Tetrafluoro[?]one 383501 NSC671886 sensitive
hsa-miR-497-5p Tetramethyl (1r,5r,6s,9s)-7-[4-[(e)-2,3-bis(4-chlorophenyl)prop-2-enoyl]oxyphenyl]-3,5-dihydroxybicyclo[3.3.1]non-2-ene-2,4,6,9-tetracarboxylate 54681588 NSC717067 resistant
hsa-miR-497-5p Thujaplicin mixture 252101 NSC73300 resistant
hsa-miR-497-5p Tunicamycin 16727450 NSC177382 resistant
hsa-miR-497-5p Verrucarin a 9,10-epoxide 5358836 NSC283445 resistant
hsa-miR-497-5p Xnivbtjmwlisex-djkkodmxsa-n 9571538 NSC681776 sensitive
hsa-miR-497-5p Z24759926 4853660 NSC743408 sensitive
hsa-miR-497-5p Z28714792 2671841 NSC746248 sensitive
hsa-miR-497-5p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-497-5p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive Low Gastric Cancer cell line (SGC7901)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive Low Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-497-5p Vincristine 5978 approved sensitive Low Gastric Cancer cell line (SGC7901)
hsa-miR-497-5p Vincristine 5978 approved sensitive Low Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive Low Colorectal Cancer cell line (HCT-116)
hsa-miR-497-5p Fluorouracil 3385 NSC19893 approved sensitive Low Colorectal Cancer cell line (HCT-116)
hsa-miR-497-5p Trail sensitive Low Colorectal Cancer cell line (HCT-116)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive Low Epidermoid Carcinoma cell line (KB-3-1, KB-CP.5, KB-CP20)
hsa-miR-497-5p Paclitaxel 36314 NSC125973 approved sensitive High Ovarian Cancer cell line (IOSE386, IOSE397, A2780, KF, SKOV3, TOUS3,TU-OC-1, OVCAR-3, OV2008, CI3)
hsa-miR-497-5p Gemcitabine 60750 NSC613327 approved sensitive Low Pancreatic Cancer cell line (BxPC-3, AsPC-1)
hsa-miR-497-5p Temozolomide 5394 NSC362856 approved resistant Low Glioma cell line (U87, U251)
hsa-miR-497-5p Platinum-based doublet chemotherapy resistant High Lung Adenocarcinoma tissue
hsa-miR-497-5p Erlotinib 176870 NSC718781 approved sensitive Low Pancreatic Cancer cell line (MIA-PaCa-2)
hsa-miR-497-5p Gemcitabine 60750 NSC613327 approved sensitive Low Pancreatic Cancer cell line (MIA-PaCa-2, SW1990)
hsa-miR-497-5p Vincristine 5978 approved sensitive High Colorectal Cancer cell line (HCT-8)
hsa-miR-497-5p Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer cell line (HCT-116)
hsa-miR-497-5p Gefitinib 123631 NSC715055 approved resistant High Lung Adenocarcinoma cell line (A549)
hsa-miR-497-5p Fluorouracil 3385 NSC19893 approved sensitive Low Colorectal Cancer tissue and cell line (SW480, LoVo)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive Low Ovarian Cancer cell line (A2780, SKOV3)
hsa-miR-497-5p Doxorubicin 31703 NSC123127 approved sensitive Low Diffuse Large B-Cell Lymphoma cell line (RI-1, U2932, Karpas-422, SUDHL4)
hsa-miR-497-5p Doxorubicin 31703 NSC123127 approved sensitive Low Diffuse Large B-Cell Lymphoma cell line (RI-1, U2932, Karpas-422, SUDHL4)
hsa-miR-497-5p Rituximab sensitive Low Diffuse Large B-Cell Lymphoma cell line (RI-1, U2932, Karpas-422, SUDHL4)
hsa-miR-497-5p Rituximab sensitive Low Diffuse Large B-Cell Lymphoma cell line (RI-1, U2932, Karpas-422, SUDHL4)
hsa-miR-497-5p Vincristine 5978 approved sensitive Low Diffuse Large B-Cell Lymphoma cell line (RI-1, U2932, Karpas-422, SUDHL4)
hsa-miR-497-5p Vincristine 5978 approved sensitive Low Diffuse Large B-Cell Lymphoma cell line (RI-1, U2932, Karpas-422, SUDHL4)
hsa-miR-497-5p Platinum 23939 resistant High Ovarian Cancer tissue
hsa-miR-497-5p Aromatase Inhibitor sensitive Low Breast Cancer cell line (MCF-7)
hsa-miR-497-5p Temozolomide 5394 NSC362856 approved resistant Low Glioma cell line (SF295, U87)
hsa-miR-497-5p Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-497-5p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive Low Urothelial Bladder Cancer cell line (T24)
hsa-miR-497-5p Gemcitabine 60750 NSC613327 approved sensitive Low Urothelial Bladder Cancer cell line (T24)
hsa-miR-497-5p Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-497-5p Azacitidine 9444 NSC102816 approved resistant High Acute Myeloid Leukemia tissue
hsa-miR-497-5p Bortezomib 387447 NSC681239 approved sensitive Low Multiple Myeloma cell line (RPMI-8266, U-266)
hsa-miR-497-5p Radioactivity Iodine sensitive High Papillary Thyroid Cancer tissue
hsa-miR-497-5p Oxaliplatin 6857599 NSC266046 approved sensitive Low Colorectal Cancer cell line (HCT-116, RKO)
hsa-miR-497-5p Fluorouracil 3385 NSC19893 approved sensitive Low Colorectal Cancer cell line (HCT-116, RKO)
hsa-miR-497-5p Paclitaxel 36314 NSC125973 approved resistant High Ovarian Cancer cell line (W1)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive High Gastric Cancer cell line (SGC7901)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive Low Laryngeal Squamous Cell Carcinoma cell line (Hep2, TU212)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive Low Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-497-5p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-497-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-497-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM43)
hsa-miR-497-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM47)
hsa-miR-497-5p Doxorubicin 31703 NSC123127 approved sensitive cell line (HS578T)
hsa-miR-497-5p Tamoxifen 2733525 NSC180973 approved resistant cell line (LCC2)
hsa-miR-497-5p Exemestane 60198 NSC713563 approved resistant cell line (MCF-7)
hsa-miR-497-5p Testosterone 6013 NSC9700 approved resistant cell line (MCF-7)
hsa-miR-497-5p Testosterone+Anastrozole resistant cell line (MCF-7)
hsa-miR-497-5p Testosterone+Exemestane resistant cell line (MCF-7)
hsa-miR-497-5p Testosterone+Letrozole resistant cell line (MCF-7)
hsa-miR-497-5p Testosterone+Tamoxifen resistant cell line (MCF-7)
hsa-miR-497-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-497-5p Sunitinib 5329102 NSC750690 approved sensitive tissue (clear cell renal cell carcinoma)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-497-5p Ethanol+Tamoxifen sensitive cell line (LY2)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (RPMI2650)
hsa-miR-497-5p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-497-5p Pegylated interferon alpha+Ribavirin sensitive tissue (chronic hepatitis C)
hsa-miR-497-5p Platinum 23939 resistant tissue (non-small cell lung cancer)
hsa-miR-497-5p Platinum-based doublet chemotherapy resistant tissue (lung adenocarcinoma)
hsa-miR-497-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (PC3PR70)
hsa-miR-497-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (PC3PR200)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-497-5p Neoadjuvant chemotherapy resistant tissue (breast cancer)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (H460)
hsa-miR-497-5p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved resistant cell line (TOV-112D)

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