miRTarBase - #MIRT055428


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pre-miRNA Information
pre-miRNA hsa-mir-497   
Genomic Coordinates chr17: 7017911 - 7018022
Synonyms MIRN497, hsa-mir-497, MIR497
Description Homo sapiens miR-497 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-497-5p
Sequence 24| CAGCAGCACACUGUGGUUUGU |44
Evidence Experimental
Experiments Array-cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 2 17 - 7017998 22499667, 24964909, 25582055, 25692236, 27229138, 28411194, 28550310, 29267965, 30022565, 29976955, 29165639, 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1217216293 1 dbSNP
rs1050536403 10 dbSNP
rs1283992109 11 dbSNP
rs1239642436 12 dbSNP
rs753897817 16 dbSNP
rs1315164260 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SHOC2   
Synonyms SIAA0862, SOC2, SUR8
Description SHOC2, leucine rich repeat scaffold protein
Transcript NM_007373   
Expression
Putative miRNA Targets on SHOC2
3'UTR of SHOC2
(miRNA target sites are highlighted)		 
>SHOC2|NM_007373|3'UTR
   1 TATAAATCTGCTGGTCCCACACACTGTTCAAAAATAGACTGCCATTAATGTTTCTTATCTATATCTGTATCTATTTATGT
  81 AGATATTGGTATATGGCAGATTTATAAAAATTGCATTATGTGTTTCTGCTAATAGAGGAATCATAGCCATTTAGAATTTT
 161 TTTTAAATTCTGTACAAAAGGCTTATATAAGTTTTCTTTGCTGAATTTGATGGATGTTTTTCTGTTGTGTAATCTGATAT
 241 GCCAGTTTGCTTAAAACATTTGCCAACACATTATGAAGTTATTAAATTTAAGGGACAGAGGTAGTATAGTTAGATATACT
 321 TTCTCTTAGGAAAAATAATGGGCAAAAATTTTTGTTGCAACTTTTCATATATATTTTCCCCTTACCAATTGTTTTATCCT
 401 TATAGTATTGTAGGCCCTGAAAGTAGAATTTTTCTTTAACTTATTTTGAGATTTGAGATTTAAATTTTATGTATTGTTTA
 481 CAGTCAGAGTAAATCACTGGATTTCTTTTGTTTGTTTTGATTTGCTCTGTTTTATTCAGTCAAATCTAGAGTTTGAATCC
 561 TCTGCTAAAGAATTTGCATCCACTGGTGTAAACAGTGAAAGGTATTTGCTTGTTGAAAAAAAAAACTGGCAAAGTGAAAA
 641 GATACAGTCAAAAATCTAGAATTTCTTTAATTTTGCTTCTCTGACGAGTTGTGAAGCAAAATACCTGAAGTGAGTCTTTG
 721 GGTAGGGGAAGGGTATTGAGACCTTTTCTAGTATGAATATTTTTTAAGTTTGGGGGAAGAGAAACTTGCAGTGAAAAGGA
 801 GTTTTTTCATTCCTGAAAGTTGCAGATCCACAAAACTAACAGGATAATTGGGCAAATAAATTACATATAAACACACACAA
 881 TCTATATATGTATATACAATGCTATATAGATATGTATTTATTATATCATAAACTACAGTAGGTAACTTTAAGGATTTCTT
 961 CCTATCCTTGTACAATGACATGAATGTCTTTCTTTGAAAACTGCAATGTATGTATGTTTCAAGGTTATTTAACAGTGTAC
1041 TATGGTTTTATATCTTGACTTGCCTTGTACATCTTTCAATTCTGGAATATCTGTGTCTAAGCACAATATCTTCACACTGT
1121 GCTGTATTGCTGCTGAACTAAATGCACTTTTCCCCACATATGGGGCACTGGCTTCAAACAATTCAGTTCAGTATCATTAC
1201 TTTTAATCTCATCTTTCCTTTCTTGGTAGTTGTTAATACAGTTATGGAAAAGAGGCACATTGCATAGAAGCCATTGGGGA
1281 GTTCAGTGGAAGTTCTGTAAGATGTGCATGTACTATTTGATGCGTTTTCTTTGCTTCACTGCTTTTAATACTTAGCAGTA
1361 TTGTTGGTCTAAGTCAATTTGATTATTGAGGAGTCTCAGAGCAAGGTGCGTTCTAGATGTCATCCTAAAAAACACTTCAT
1441 ATATAATTAATCACTATTTTGTATAATTACATATTGCTGCTTGTGTGTTTTTTTTTTTTTCCATTTAGTTGGGCGTTGTG
1521 TTTTACACAAAACCATTTTTGAATTAAGGCTATGATATTAAGATAGAAATTTGGACTGTTGTTCTGCTTTTCCTGGCACT
1601 CAAATTCATGACTAGTTTTGAGGTCAAACCTATGTTCGTAATGAGAGATTTTATAAGGATCAACTAAGAAATGGAAGGCA
1681 GGTGAAGATATAAAACCCTAGAATGCTTAAATGTGCTGTAAAACTATTGTAGATGTCACTGGATTTTACCAAGTAATATC
1761 CTTTCTTTTTTTTTTCCCCCCATCTGCTGTGGCTTTTCAGTTAAAATTTTGTTTATAAAAGGAATTTGTTTATTACAGCT
1841 CTACCTAGAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uguUUGGUGUCACACGACGAc 5'
             ||::|||   ||||||| 
Target 5' tatAATTACATATTGCTGCTt 3'
 1462 - 1482 158.00 -12.80
2 
miRNA  3' ugUUUGGUGUCAC---ACGACGAc 5'
            | ||:::: ||   ||||||| 
Target 5' tcACACTGTGCTGTATTGCTGCTg 3'
 1112 - 1135 151.00 -18.00
3 
miRNA  3' ugUUUGGUGU----CAC-ACGACGAc 5'
            |||:::||    ||| | ||||| 
Target 5' aaAAATTGCATTATGTGTTTCTGCTa 3'
 106 - 131 129.00 -11.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
181525 4 ClinVar
378581 17 ClinVar
984487 17 ClinVar
879344 21 ClinVar
298865 165 ClinVar
298866 405 ClinVar
298867 506 ClinVar
298868 519 ClinVar
298869 615 ClinVar
298870 616 ClinVar
298871 657 ClinVar
879705 686 ClinVar
298872 698 ClinVar
298873 774 ClinVar
879706 826 ClinVar
298874 915 ClinVar
298875 959 ClinVar
877760 980 ClinVar
877761 991 ClinVar
298876 1062 ClinVar
298877 1107 ClinVar
298878 1219 ClinVar
298879 1246 ClinVar
877762 1270 ClinVar
298880 1324 ClinVar
298881 1325 ClinVar
878792 1382 ClinVar
298882 1484 ClinVar
298883 1486 ClinVar
298884 1487 ClinVar
298885 1488 ClinVar
298886 1504 ClinVar
878793 1509 ClinVar
298887 1576 ClinVar
298888 1766 ClinVar
298889 1776 ClinVar
COSN30518494 17 COSMIC
COSN30453026 23 COSMIC
COSN30599808 47 COSMIC
COSN31554104 147 COSMIC
COSN8529214 147 COSMIC
COSN28840592 165 COSMIC
COSN26056258 210 COSMIC
COSN6056671 264 COSMIC
COSN6056672 419 COSMIC
COSN16529725 726 COSMIC
COSN17540041 967 COSMIC
COSN16698609 1010 COSMIC
COSN23635756 1094 COSMIC
COSN26551615 1125 COSMIC
COSN26556972 1136 COSMIC
COSN15325663 1161 COSMIC
COSN28797786 1293 COSMIC
COSN28939734 1488 COSMIC
COSN20107548 1501 COSMIC
COSN14463567 1603 COSMIC
COSN23108089 1776 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs767523465 3 dbSNP
rs143187497 4 dbSNP
rs760047969 11 dbSNP
rs377043455 12 dbSNP
rs938277839 14 dbSNP
rs574959049 16 dbSNP
rs753327392 17 dbSNP
rs371005619 21 dbSNP
rs753016007 22 dbSNP
rs1355437825 24 dbSNP
rs1455226481 27 dbSNP
rs944382341 36 dbSNP
rs1301838443 38 dbSNP
rs1353178224 39 dbSNP
rs758762850 45 dbSNP
rs1293346959 47 dbSNP
rs1317261860 51 dbSNP
rs1222504732 62 dbSNP
rs775803610 62 dbSNP
rs1169548041 66 dbSNP
rs1040144710 68 dbSNP
rs575011429 70 dbSNP
rs1421610660 72 dbSNP
rs542333379 74 dbSNP
rs1196568516 84 dbSNP
rs866531238 87 dbSNP
rs1248746001 91 dbSNP
rs1479832656 96 dbSNP
rs1482109220 98 dbSNP
rs1224246962 100 dbSNP
rs377205004 101 dbSNP
rs1181615270 102 dbSNP
rs1042167767 105 dbSNP
rs1204306036 108 dbSNP
rs1252410751 111 dbSNP
rs900213298 114 dbSNP
rs931728986 115 dbSNP
rs902242330 116 dbSNP
rs761226703 119 dbSNP
rs1412730473 123 dbSNP
rs1284044651 141 dbSNP
rs936410980 145 dbSNP
rs772535731 150 dbSNP
rs1297359330 157 dbSNP
rs896472847 157 dbSNP
rs191293913 165 dbSNP
rs1402299398 166 dbSNP
rs201494424 175 dbSNP
rs1166465738 184 dbSNP
rs1174166137 184 dbSNP
rs900133151 188 dbSNP
rs969409307 192 dbSNP
rs1200399961 209 dbSNP
rs1368377995 213 dbSNP
rs576218739 217 dbSNP
rs996096984 230 dbSNP
rs1030249563 233 dbSNP
rs890328883 241 dbSNP
rs1481154857 243 dbSNP
rs1308151104 250 dbSNP
rs1260463910 252 dbSNP
rs1005107793 259 dbSNP
rs1323504842 271 dbSNP
rs1351827066 280 dbSNP
rs1444927340 281 dbSNP
rs1334140796 283 dbSNP
rs1015699953 290 dbSNP
rs542446944 293 dbSNP
rs543400072 294 dbSNP
rs1378832463 302 dbSNP
rs1334494312 307 dbSNP
rs1469210520 308 dbSNP
rs764385450 310 dbSNP
rs1406772865 315 dbSNP
rs1173750036 324 dbSNP
rs957249586 331 dbSNP
rs1362769468 332 dbSNP
rs989120443 349 dbSNP
rs1441202810 352 dbSNP
rs1378901885 353 dbSNP
rs182433736 354 dbSNP
rs1229311118 359 dbSNP
rs1461231568 362 dbSNP
rs1026947396 368 dbSNP
rs944608848 372 dbSNP
rs959364848 380 dbSNP
rs975712602 381 dbSNP
rs1260287622 386 dbSNP
rs539394184 405 dbSNP
rs918158727 406 dbSNP
rs1204745760 408 dbSNP
rs970944296 414 dbSNP
rs1312594067 415 dbSNP
rs1451650872 416 dbSNP
rs978684067 429 dbSNP
rs532446734 431 dbSNP
rs1383364226 434 dbSNP
rs1336075730 437 dbSNP
rs1275382202 454 dbSNP
rs931697816 459 dbSNP
rs1288991319 486 dbSNP
rs1048829012 488 dbSNP
rs1439647217 494 dbSNP
rs1421085522 495 dbSNP
rs1383039352 496 dbSNP
rs887931765 501 dbSNP
rs541359882 502 dbSNP
rs1161987839 503 dbSNP
rs371679867 506 dbSNP
rs1236900795 507 dbSNP
rs1190217442 508 dbSNP
rs1472995511 511 dbSNP
rs924105012 511 dbSNP
rs936426575 516 dbSNP
rs886046731 519 dbSNP
rs559270881 524 dbSNP
rs896700397 528 dbSNP
rs1053493127 532 dbSNP
rs921636466 541 dbSNP
rs1245593167 542 dbSNP
rs931627740 557 dbSNP
rs573586846 560 dbSNP
rs1051710493 570 dbSNP
rs1448456922 571 dbSNP
rs905219486 579 dbSNP
rs1325805726 584 dbSNP
rs1168857275 589 dbSNP
rs1401314899 591 dbSNP
rs890349094 593 dbSNP
rs1004777626 596 dbSNP
rs1302137196 602 dbSNP
rs1424979589 606 dbSNP
rs1391868200 613 dbSNP
rs886046732 615 dbSNP
rs1032456352 616 dbSNP
rs886046733 616 dbSNP
rs957423845 616 dbSNP
rs1194401816 617 dbSNP
rs1010032840 624 dbSNP
rs1036617326 627 dbSNP
rs1020545643 634 dbSNP
rs1452454829 635 dbSNP
rs1359147806 636 dbSNP
rs1291695937 640 dbSNP
rs965923949 643 dbSNP
rs560726584 646 dbSNP
rs898963211 650 dbSNP
rs1363493914 651 dbSNP
rs557334390 657 dbSNP
rs1220462515 660 dbSNP
rs1343095268 678 dbSNP
rs749942762 686 dbSNP
rs984941982 687 dbSNP
rs1198858390 689 dbSNP
rs1332486270 692 dbSNP
rs1325898196 694 dbSNP
rs189140753 698 dbSNP
rs1396298913 708 dbSNP
rs148246156 713 dbSNP
rs1427259549 720 dbSNP
rs1036496682 725 dbSNP
rs1024952105 745 dbSNP
rs1478454262 761 dbSNP
rs114628508 774 dbSNP
rs1179330179 776 dbSNP
rs978335298 785 dbSNP
rs1258551680 789 dbSNP
rs1464279974 790 dbSNP
rs924106725 793 dbSNP
rs193126887 799 dbSNP
rs989262645 810 dbSNP
rs905188414 817 dbSNP
rs1219340794 821 dbSNP
rs921664394 826 dbSNP
rs1277394430 834 dbSNP
rs1441111625 837 dbSNP
rs1335514894 841 dbSNP
rs1332517146 843 dbSNP
rs1449588119 848 dbSNP
rs185620695 852 dbSNP
rs1476745147 866 dbSNP
rs1404572126 867 dbSNP
rs1175712976 868 dbSNP
rs1415124112 871 dbSNP
rs1427429588 873 dbSNP
rs1157045067 875 dbSNP
rs540708199 880 dbSNP
rs1469857967 884 dbSNP
rs931658865 887 dbSNP
rs1180300814 892 dbSNP
rs1425301590 893 dbSNP
rs1459895177 893 dbSNP
rs1242463257 898 dbSNP
rs766192638 903 dbSNP
rs751455255 905 dbSNP
rs1051445922 908 dbSNP
rs1210798748 911 dbSNP
rs1415498566 914 dbSNP
rs1054277943 915 dbSNP
rs189223963 915 dbSNP
rs940610806 928 dbSNP
rs192135385 930 dbSNP
rs1242769222 935 dbSNP
rs1381147331 937 dbSNP
rs1302765704 940 dbSNP
rs1449495369 947 dbSNP
rs1434913555 950 dbSNP
rs1316376326 953 dbSNP
rs372493479 959 dbSNP
rs1160168322 974 dbSNP
rs1381187671 974 dbSNP
rs1442529300 978 dbSNP
rs994617323 980 dbSNP
rs1231118801 985 dbSNP
rs1048485840 986 dbSNP
rs1274288913 991 dbSNP
rs1484222860 994 dbSNP
rs895255595 1006 dbSNP
rs1345831053 1007 dbSNP
rs568680803 1025 dbSNP
rs1266166977 1028 dbSNP
rs1464266150 1039 dbSNP
rs536012063 1041 dbSNP
rs1209180040 1043 dbSNP
rs1488373301 1052 dbSNP
rs1287730466 1058 dbSNP
rs1263374537 1059 dbSNP
rs1449477956 1061 dbSNP
rs530047047 1062 dbSNP
rs886046734 1062 dbSNP
rs1312516949 1064 dbSNP
rs1025405291 1065 dbSNP
rs557280270 1079 dbSNP
rs906496375 1080 dbSNP
rs1229376057 1090 dbSNP
rs751517745 1092 dbSNP
rs1268453719 1094 dbSNP
rs1399485023 1101 dbSNP
rs1361349390 1105 dbSNP
rs118172559 1107 dbSNP
rs997422272 1108 dbSNP
rs1031242870 1109 dbSNP
rs1165245122 1117 dbSNP
rs1481134517 1133 dbSNP
rs1417298918 1134 dbSNP
rs184177524 1140 dbSNP
rs1179205114 1155 dbSNP
rs1477853004 1156 dbSNP
rs958219170 1158 dbSNP
rs1410473061 1162 dbSNP
rs1457023571 1166 dbSNP
rs1160421289 1171 dbSNP
rs1490099635 1173 dbSNP
rs1387633035 1174 dbSNP
rs1222813984 1181 dbSNP
rs1323961016 1185 dbSNP
rs1028950726 1188 dbSNP
rs953024686 1194 dbSNP
rs984436423 1209 dbSNP
rs1280230768 1210 dbSNP
rs1403283625 1212 dbSNP
rs1367202930 1218 dbSNP
rs886046735 1219 dbSNP
rs908876475 1223 dbSNP
rs961790746 1229 dbSNP
rs972240205 1232 dbSNP
rs1169871048 1236 dbSNP
rs1466115990 1240 dbSNP
rs1425127004 1241 dbSNP
rs754913685 1246 dbSNP
rs1479883283 1248 dbSNP
rs1029142477 1259 dbSNP
rs953120890 1260 dbSNP
rs1315571572 1265 dbSNP
rs772654155 1270 dbSNP
rs1231566697 1278 dbSNP
rs911549613 1282 dbSNP
rs141791891 1298 dbSNP
rs972421078 1305 dbSNP
rs576948558 1306 dbSNP
rs1286362382 1309 dbSNP
rs936926753 1314 dbSNP
rs1053763780 1317 dbSNP
rs1330487326 1320 dbSNP
rs371721188 1324 dbSNP
rs559572636 1325 dbSNP
rs1173551406 1332 dbSNP
rs894280946 1339 dbSNP
rs1041181045 1340 dbSNP
rs1177747592 1353 dbSNP
rs1416986919 1355 dbSNP
rs1236675268 1356 dbSNP
rs948143573 1365 dbSNP
rs188505184 1378 dbSNP
rs1240587158 1379 dbSNP
rs747905159 1381 dbSNP
rs997392575 1382 dbSNP
rs1482963417 1387 dbSNP
rs1256707298 1388 dbSNP
rs1235668007 1393 dbSNP
rs757582531 1395 dbSNP
rs1046472169 1410 dbSNP
rs779208280 1411 dbSNP
rs541969990 1418 dbSNP
rs1378950926 1420 dbSNP
rs1290232538 1421 dbSNP
rs1334595294 1428 dbSNP
rs1490693236 1432 dbSNP
rs780618180 1442 dbSNP
rs745972322 1443 dbSNP
rs796796451 1446 dbSNP
rs1304098805 1457 dbSNP
rs1451120924 1462 dbSNP
rs563188768 1464 dbSNP
rs1379303470 1472 dbSNP
rs199880082 1482 dbSNP
rs180979375 1484 dbSNP
rs1456714361 1485 dbSNP
rs1382621262 1486 dbSNP
rs549502834 1486 dbSNP
rs753811687 1486 dbSNP
rs776585204 1486 dbSNP
rs143768227 1487 dbSNP
rs759715534 1487 dbSNP
rs7074770 1488 dbSNP
rs769907720 1488 dbSNP
rs771402535 1488 dbSNP
rs1355581834 1489 dbSNP
rs971773144 1489 dbSNP
rs1312708932 1490 dbSNP
rs552284342 1491 dbSNP
rs1341022670 1493 dbSNP
rs1306221023 1501 dbSNP
rs1314154214 1501 dbSNP
rs1349977761 1502 dbSNP
rs1410300255 1503 dbSNP
rs1327552 1504 dbSNP
rs1309063358 1507 dbSNP
rs1338482281 1508 dbSNP
rs202206864 1509 dbSNP
rs1362824766 1510 dbSNP
rs1265641641 1512 dbSNP
rs1161852458 1513 dbSNP
rs528458429 1515 dbSNP
rs1369554224 1516 dbSNP
rs1189645426 1524 dbSNP
rs771841691 1524 dbSNP
rs1273217366 1529 dbSNP
rs1483103637 1537 dbSNP
rs980866319 1553 dbSNP
rs1031691813 1560 dbSNP
rs1194621920 1572 dbSNP
rs886046736 1576 dbSNP
rs1489405248 1580 dbSNP
rs1287419229 1585 dbSNP
rs1209023344 1588 dbSNP
rs1196815863 1600 dbSNP
rs1356886424 1605 dbSNP
rs926807353 1605 dbSNP
rs747506750 1609 dbSNP
rs936915996 1611 dbSNP
rs990164034 1616 dbSNP
rs865926990 1621 dbSNP
rs913891085 1626 dbSNP
rs1801901 1630 dbSNP
rs945404848 1633 dbSNP
rs1446622504 1634 dbSNP
rs546692011 1638 dbSNP
rs1166964077 1639 dbSNP
rs1041149992 1642 dbSNP
rs568695891 1683 dbSNP
rs953485111 1692 dbSNP
rs901220679 1707 dbSNP
rs1464559931 1716 dbSNP
rs1801900 1719 dbSNP
rs1422945226 1726 dbSNP
rs932733512 1731 dbSNP
rs373459532 1753 dbSNP
rs1462620843 1756 dbSNP
rs1299800886 1760 dbSNP
rs1245211042 1766 dbSNP
rs527775221 1766 dbSNP
rs886046737 1766 dbSNP
rs888963635 1767 dbSNP
rs1269247858 1772 dbSNP
rs1247310563 1776 dbSNP
rs535776105 1776 dbSNP
rs1219941211 1782 dbSNP
rs1313108211 1793 dbSNP
rs777538590 1803 dbSNP
rs1018684517 1804 dbSNP
rs551193817 1815 dbSNP
rs971775017 1824 dbSNP
rs746829098 1825 dbSNP
rs1296419884 1835 dbSNP
rs1326008783 1837 dbSNP
rs993162076 1839 dbSNP
rs1342244561 1842 dbSNP
rs920235268 1844 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545212. RNA binding protein: AGO1. Condition:Control PAR-CLIP data was present in GSM545214. RNA binding protein: AGO3. Condition:Control PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection PAR-CLIP data was present in GSM545217. RNA binding protein: AGO2. Condition:miR-7 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 8036.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714646. RNA binding protein: AGO2. Condition:mildMNase ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 8036.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065667. RNA binding protein: AGO1. Condition:4-thiouridine "PAR-CLIP data was present in GSM1065668. RNA binding protein: AGO1. Condition:4-thiouridine "PAR-CLIP data was present in GSM1065669. RNA binding protein: AGO1. Condition:4-thiouridine "PAR-CLIP data was present in GSM1065670. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
Experimental Support 4 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
Experimental Support 5 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions MCF7
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in SRR1045082. RNA binding protein: AGO2. Condition:Untreated ...

- Farazi TA; Ten Hoeve JJ; Brown M; et al., 2014, Genome biology.

Article - Farazi TA; Ten Hoeve JJ; Brown M; et al.
- Genome biology, 2014
BACKGROUND: Various microRNAs (miRNAs) are up- or downregulated in tumors. However, the repression of cognate miRNA targets responsible for the phenotypic effects of this dysregulation in patients remains largely unexplored. To define miRNA targets and associated pathways, together with their relationship to outcome in breast cancer, we integrated patient-paired miRNA-mRNA expression data with a set of validated miRNA targets and pathway inference. RESULTS: To generate a biochemically-validated set of miRNA-binding sites, we performed argonaute-2 photoactivatable-ribonucleoside-enhanced crosslinking and immunoprecipitation (AGO2-PAR-CLIP) in MCF7 cells. We then defined putative miRNA-target interactions using a computational model, which ranked and selected additional TargetScan-predicted interactions based on features of our AGO2-PAR-CLIP binding-site data. We subselected modeled interactions according to the abundance of their constituent miRNA and mRNA transcripts in tumors, and we took advantage of the variability of miRNA expression within molecular subtypes to detect miRNA repression. Interestingly, our data suggest that miRNA families control subtype-specific pathways; for example, miR-17, miR-19a, miR-25, and miR-200b show high miRNA regulatory activity in the triple-negative, basal-like subtype, whereas miR-22 and miR-24 do so in the HER2 subtype. An independent dataset validated our findings for miR-17 and miR-25, and showed a correlation between the expression levels of miR-182 targets and overall patient survival. Pathway analysis associated miR-17, miR-19a, and miR-200b with leukocyte transendothelial migration. CONCLUSIONS: We combined PAR-CLIP data with patient expression data to predict regulatory miRNAs, revealing potential therapeutic targets and prognostic markers in breast cancer.
LinkOut: [PMID: 24398324]
CLIP-seq Support 1 for dataset GSM545212
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / Control
Location of target site ENST00000369452.4 | 3UTR | GUAUAAUUACAUAUUGCUGCUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM545214
Method / RBP PAR-CLIP / AGO3
Cell line / Condition HEK293 / Control
Location of target site ENST00000369452.4 | 3UTR | UAUAAUUACAUAUUGCUGCUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000369452.4 | 3UTR | AUCACUAUUUUGUAUAAUUACAUAUUGCUGCUUGUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM545217
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-7 transfection
Location of target site ENST00000369452.4 | 3UTR | UAUAAUUACAUAUUGCUGCUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000369452.4 | 3UTR | UAUAAUUACAUAUUGCUGCUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM714646
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / mildMNase, repA
Location of target site ENST00000369452.4 | 3UTR | AUCUUCACACUGUGCUGUAUUGCUGCUGAACUAAAUGCACUUUUCCCCACAUAUGGGGCACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM1065667
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_6
Location of target site ENST00000369452.4 | 3UTR | GUAUAAUUACAUAUUGCUGCUUGUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
CLIP-seq Support 8 for dataset GSM1065668
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_7
Location of target site ENST00000369452.4 | 3UTR | UAUAAUUACAUAUUGCUGCUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
CLIP-seq Support 9 for dataset GSM1065669
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_8
Location of target site ENST00000369452.4 | 3UTR | UAUAAUUACAUAUUGCUGCUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
CLIP-seq Support 10 for dataset GSM1065670
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / 4-thiouridine, 3_ML_LG
Location of target site ENST00000369452.4 | 3UTR | UAUAAUUACAUAUUGCUGCUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
CLIP-seq Support 11 for dataset SRR1045082
Method / RBP PAR-CLIP / AGO2
Cell line / Condition MCF7 / Untreated
Location of target site ENST00000369452.4 | 3UTR | UAUAAUUACAUAUUGCUGCUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 24398324 / SRX388831
CLIP-seq Viewer Link
CLIP-seq Support 12 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000369452.4 | 3UTR | UAUAAUUACAUAUUGCUGCUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE42095 Differentiated embryonic stem cells 0.681 1.7e-4 0.333 6.0e-2 23 Click to see details
GSE28544 Breast cancer 0.634 4.4e-4 0.655 2.6e-4 24 Click to see details
GSE19350 CNS germ cell tumors 0.611 1.7e-2 0.559 2.9e-2 12 Click to see details
GSE26953 Aortic valvular endothelial cells 0.344 5.0e-2 0.238 1.3e-1 24 Click to see details
GSE38226 Liver fibrosis 0.352 5.9e-2 0.226 1.6e-1 21 Click to see details
GSE19536 Breast cancer 0.148 7.1e-2 0.109 1.4e-1 100 Click to see details
GSE19783 ER- ER- breast cancer 0.16 7.9e-2 0.109 1.7e-1 79 Click to see details
GSE21032 Prostate cancer 0.15 8.8e-2 0.137 1.1e-1 83 Click to see details
GSE28260 Renal cortex and medulla -0.392 9.3e-2 -0.390 9.4e-2 13 Click to see details
GSE32688 Pancreatic cancer 0.227 1.1e-1 0.279 6.1e-2 32 Click to see details
GSE17306 Multiple myeloma 0.181 1.1e-1 0.386 3.1e-3 49 Click to see details
GSE21849 B cell lymphoma 0.219 1.3e-1 0.236 1.1e-1 29 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.265 1.3e-1 0.367 5.6e-2 20 Click to see details
GSE19783 ER+ ER+ breast cancer 0.262 1.3e-1 0.044 4.3e-1 20 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.144 2.5e-1 -0.254 1.1e-1 25 Click to see details
GSE21687 Ependynoma primary tumors -0.073 2.8e-1 -0.008 4.7e-1 64 Click to see details
GSE35602 Colorectal cancer stromal tissue -0.112 3.0e-1 -0.225 1.4e-1 25 Click to see details
GSE17498 Multiple myeloma 0.022 4.5e-1 0.024 4.4e-1 40 Click to see details
GSE17498 Multiple myeloma 0.022 4.5e-1 0.024 4.4e-1 40 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
THCA 0.431 0 0.363 0 59 Click to see details
PAAD 0.957 0.02 0.800 0.1 4 Click to see details
CHOL 0.584 0.05 0.150 0.35 9 Click to see details
CESC -0.985 0.06 -0.500 0.33 3 Click to see details
LUAD -0.38 0.11 -0.224 0.24 12 Click to see details
ESCA -0.396 0.11 -0.400 0.11 11 Click to see details
COAD -0.411 0.16 -0.405 0.16 8 Click to see details
PRAD -0.129 0.19 -0.148 0.15 50 Click to see details
KIRC -0.105 0.2 -0.098 0.21 68 Click to see details
KICH -0.176 0.2 -0.164 0.22 25 Click to see details
LIHC -0.088 0.27 -0.139 0.17 49 Click to see details
STAD 0.1 0.29 0.066 0.36 32 Click to see details
HNSC -0.065 0.34 -0.038 0.41 42 Click to see details
BLCA 0.1 0.35 0.038 0.44 18 Click to see details
UCEC 0.093 0.35 0.025 0.46 19 Click to see details
PCPG 0.29 0.41 0.500 0.33 3 Click to see details
BRCA -0.015 0.45 0.106 0.17 84 Click to see details
LUSC 0.022 0.45 0.015 0.46 38 Click to see details
KIRP -0.009 0.48 0.002 0.5 32 Click to see details
KIRP -0.009 0.48 0.002 0.5 32 Click to see details
KIRP -0.009 0.48 0.002 0.5 32 Click to see details
437 hsa-miR-497-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT006078 RAF1 Raf-1 proto-oncogene, serine/threonine kinase 3 1
MIRT006079 RUNX2 runt related transcription factor 2 3 1
MIRT006785 IGF1R insulin like growth factor 1 receptor 3 3
MIRT007165 MAP2K1 mitogen-activated protein kinase kinase 1 3 1
MIRT041183 EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1 1
MIRT041184 TCEA1 transcription elongation factor A1 1 1
MIRT041185 HIST1H3H histone cluster 1 H3 family member h 1 1
MIRT041186 ALDH9A1 aldehyde dehydrogenase 9 family member A1 1 1
MIRT041187 DESI2 desumoylating isopeptidase 2 1 1
MIRT041188 HIST2H3A histone cluster 2 H3 family member a 1 1
MIRT041189 PANK2 pantothenate kinase 2 1 1
MIRT041190 ATXN7L3B ataxin 7 like 3B 2 5
MIRT041191 BRD1 bromodomain containing 1 1 1
MIRT053046 WEE1 WEE1 G2 checkpoint kinase 5 5
MIRT053193 DICER1 dicer 1, ribonuclease III 2 1
MIRT053195 HDGF heparin binding growth factor 5 5
MIRT053471 BCL2 BCL2, apoptosis regulator 4 1
MIRT053773 EIF4E eukaryotic translation initiation factor 4E 3 1
MIRT054419 BIRC5 baculoviral IAP repeat containing 5 2 1
MIRT054420 WNT7A Wnt family member 7A 2 1
MIRT054756 SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2 1
MIRT054859 CHEK1 checkpoint kinase 1 5 3
MIRT055428 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 10
MIRT055819 PLEKHA1 pleckstrin homology domain containing A1 2 2
MIRT057519 CEP55 centrosomal protein 55 2 8
MIRT057739 ZDHHC16 zinc finger DHHC-type containing 16 2 2
MIRT060581 CCND1 cyclin D1 2 2
MIRT061010 C1ORF21 chromosome 1 open reading frame 21 2 6
MIRT061251 AMOTL1 angiomotin like 1 2 12
MIRT064690 CCND2 cyclin D2 2 4
MIRT065721 TARBP2 TARBP2, RISC loading complex RNA binding subunit 2 4
MIRT066299 MTFR1L mitochondrial fission regulator 1 like 2 2
MIRT066317 USP15 ubiquitin specific peptidase 15 2 2
MIRT071213 FCF1 FCF1, rRNA-processing protein 2 2
MIRT072827 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2 4
MIRT074535 PAGR1 PAXIP1 associated glutamate rich protein 1 2 4
MIRT075257 SNTB2 syntrophin beta 2 2 4
MIRT075279 VPS4A vacuolar protein sorting 4 homolog A 2 8
MIRT075899 C16ORF72 chromosome 16 open reading frame 72 2 6
MIRT076797 GOSR1 golgi SNAP receptor complex member 1 2 2
MIRT078288 RPS6KB1 ribosomal protein S6 kinase B1 2 2
MIRT079660 NAPG NSF attachment protein gamma 2 12
MIRT080017 GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 2 4
MIRT081649 CCNE1 cyclin E1 4 6
MIRT082990 PNPLA6 patatin like phospholipase domain containing 6 2 2
MIRT083271 ZCCHC3 zinc finger CCHC-type containing 3 2 6
MIRT084467 SOWAHC sosondowah ankyrin repeat domain family member C 2 4
MIRT086014 UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 2 2
MIRT087429 ZNRF3 zinc and ring finger 3 2 2
MIRT087560 YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta 2 2
MIRT089113 B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 2 4
MIRT089213 ACTR2 ARP2 actin related protein 2 homolog 2 2
MIRT091676 RARB retinoic acid receptor beta 2 6
MIRT093689 PI4K2B phosphatidylinositol 4-kinase type 2 beta 2 6
MIRT096240 CANX calnexin 2 2
MIRT099637 E2F3 E2F transcription factor 3 2 1
MIRT100212 PPP1R11 protein phosphatase 1 regulatory inhibitor subunit 11 2 2
MIRT100370 HSPA1B heat shock protein family A (Hsp70) member 1B 2 6
MIRT100573 PIM1 Pim-1 proto-oncogene, serine/threonine kinase 2 2
MIRT100742 VEGFA vascular endothelial growth factor A 2 12
MIRT100901 CD2AP CD2 associated protein 2 2
MIRT102442 CALU calumenin 2 2
MIRT102637 UBN2 ubinuclein 2 2 10
MIRT102976 EN2 engrailed homeobox 2 2 6
MIRT103098 MAFK MAF bZIP transcription factor K 2 4
MIRT103860 FOXK1 forkhead box K1 2 2
MIRT104021 USP42 ubiquitin specific peptidase 42 2 6
MIRT104237 DMTF1 cyclin D binding myb like transcription factor 1 2 2
MIRT106303 ZFHX4 zinc finger homeobox 4 2 6
MIRT106738 RAD23B RAD23 homolog B, nucleotide excision repair protein 2 2
MIRT107223 ZBTB34 zinc finger and BTB domain containing 34 2 2
MIRT107690 RECK reversion inducing cysteine rich protein with kazal motifs 2 2
MIRT109246 ZNF275 zinc finger protein 275 2 2
MIRT110059 OGT O-linked N-acetylglucosamine (GlcNAc) transferase 2 6
MIRT112977 LUZP1 leucine zipper protein 1 2 6
MIRT114931 CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 2 2
MIRT117661 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT120685 PAK2 p21 (RAC1) activated kinase 2 2 2
MIRT127741 ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2 2
MIRT133779 SKI SKI proto-oncogene 2 2
MIRT140154 SPRED1 sprouty related EVH1 domain containing 1 2 2
MIRT140830 SMAD3 SMAD family member 3 1 1
MIRT142250 DCTN5 dynactin subunit 5 2 8
MIRT152289 TNFSF9 TNF superfamily member 9 2 2
MIRT154056 RASSF2 Ras association domain family member 2 2 2
MIRT156471 ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) 2 2
MIRT158534 TNRC6B trinucleotide repeat containing 6B 2 4
MIRT165184 GRAMD3 GRAM domain containing 2B 2 2
MIRT165908 CREBRF CREB3 regulatory factor 2 2
MIRT175238 PSAT1 phosphoserine aminotransferase 1 2 6
MIRT179015 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 2
MIRT180915 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 8
MIRT186376 PNRC2 proline rich nuclear receptor coactivator 2 2 2
MIRT189765 CDADC1 cytidine and dCMP deaminase domain containing 1 2 2
MIRT189966 AGO4 argonaute 4, RISC catalytic component 2 2
MIRT190189 GPR180 G protein-coupled receptor 180 2 6
MIRT191461 PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A 2 2
MIRT191630 SLC39A9 solute carrier family 39 member 9 2 6
MIRT194244 FAM103A1 family with sequence similarity 103 member A1 2 6
MIRT194910 RBBP6 RB binding protein 6, ubiquitin ligase 2 8
MIRT196458 TAOK1 TAO kinase 1 2 2
MIRT201461 SNRPB2 small nuclear ribonucleoprotein polypeptide B2 2 8
MIRT204598 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 8
MIRT204629 MOB4 MOB family member 4, phocein 2 8
MIRT204745 BZW1 basic leucine zipper and W2 domains 1 2 12
MIRT206024 NUP50 nucleoporin 50 2 6
MIRT211203 FGF2 fibroblast growth factor 2 2 4
MIRT211318 HSPA4L heat shock protein family A (Hsp70) member 4 like 3 5
MIRT212612 RBPJ recombination signal binding protein for immunoglobulin kappa J region 2 8
MIRT217748 TBPL1 TATA-box binding protein like 1 2 2
MIRT223696 FZD6 frizzled class receptor 6 4 6
MIRT224970 BAG4 BCL2 associated athanogene 4 2 2
MIRT229352 ZNF449 zinc finger protein 449 2 2
MIRT229865 YIPF6 Yip1 domain family member 6 2 2
MIRT234347 MSL1 male specific lethal 1 homolog 2 8
MIRT247242 ELK4 ELK4, ETS transcription factor 2 4
MIRT247372 GABARAPL1 GABA type A receptor associated protein like 1 2 6
MIRT249454 ZNF691 zinc finger protein 691 2 4
MIRT251498 DYNLL2 dynein light chain LC8-type 2 2 4
MIRT255340 SRPRB SRP receptor beta subunit 2 4
MIRT256312 CDC42SE2 CDC42 small effector 2 2 2
MIRT258415 WIPI2 WD repeat domain, phosphoinositide interacting 2 2 2
MIRT265062 TBRG1 transforming growth factor beta regulator 1 2 2
MIRT267533 C1ORF226 chromosome 1 open reading frame 226 2 2
MIRT270557 SETD1B SET domain containing 1B 2 2
MIRT273670 HOXC8 homeobox C8 2 2
MIRT274746 RAB3IP RAB3A interacting protein 2 2
MIRT277510 PPP2R5C protein phosphatase 2 regulatory subunit B'gamma 2 4
MIRT282539 SLCO3A1 solute carrier organic anion transporter family member 3A1 2 2
MIRT289636 CBX2 chromobox 2 2 2
MIRT294288 ZFP28 ZFP28 zinc finger protein 2 2
MIRT295816 CHMP4B charged multivesicular body protein 4B 2 2
MIRT297783 GABPA GA binding protein transcription factor alpha subunit 2 4
MIRT300112 STRADB STE20-related kinase adaptor beta 2 2
MIRT300999 MTMR3 myotubularin related protein 3 2 2
MIRT302620 CRIM1 cysteine rich transmembrane BMP regulator 1 2 6
MIRT302830 SOCS5 suppressor of cytokine signaling 5 2 2
MIRT307146 CTDSPL CTD small phosphatase like 2 4
MIRT313680 ITGA2 integrin subunit alpha 2 2 2
MIRT314056 PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 2 8
MIRT317726 PPIL1 peptidylprolyl isomerase like 1 2 6
MIRT319336 CAPZA2 capping actin protein of muscle Z-line alpha subunit 2 2 2
MIRT320633 ZNRF2 zinc and ring finger 2 2 2
MIRT326307 OCRL OCRL, inositol polyphosphate-5-phosphatase 2 2
MIRT327969 CHIC1 cysteine rich hydrophobic domain 1 2 6
MIRT367270 CRKL CRK like proto-oncogene, adaptor protein 2 2
MIRT437794 BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 2 1
MIRT437795 CDK4 cyclin dependent kinase 4 2 1
MIRT437796 CCND3 cyclin D3 2 1
MIRT437797 CDC25A cell division cycle 25A 4 3
MIRT443810 SIDT2 SID1 transmembrane family member 2 2 2
MIRT446503 ASCC1 activating signal cointegrator 1 complex subunit 1 2 2
MIRT447773 DMRT2 doublesex and mab-3 related transcription factor 2 2 2
MIRT448442 TLL1 tolloid like 1 2 2
MIRT449185 LUC7L3 LUC7 like 3 pre-mRNA splicing factor 2 2
MIRT451834 ALDH3B1 aldehyde dehydrogenase 3 family member B1 2 2
MIRT453283 EFTUD2 elongation factor Tu GTP binding domain containing 2 2 2
MIRT453749 CSNK1E casein kinase 1 epsilon 2 2
MIRT454965 TPM2 tropomyosin 2 2 2
MIRT456862 ZNF460 zinc finger protein 460 2 10
MIRT460219 FGFR4 fibroblast growth factor receptor 4 2 2
MIRT460433 DOCK11 dedicator of cytokinesis 11 2 2
MIRT461559 ACTR3B ARP3 actin related protein 3 homolog B 2 2
MIRT463165 ZNF367 zinc finger protein 367 2 10
MIRT464665 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 8
MIRT464749 UBE2Q1 ubiquitin conjugating enzyme E2 Q1 2 2
MIRT465161 TSC22D2 TSC22 domain family member 2 2 2
MIRT465565 TOB2 transducer of ERBB2, 2 2 2
MIRT465929 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 8
MIRT466012 TMEM189 transmembrane protein 189 2 8
MIRT466293 TM4SF1 transmembrane 4 L six family member 1 2 2
MIRT466432 TFAP2A transcription factor AP-2 alpha 2 8
MIRT466922 STK38 serine/threonine kinase 38 2 10
MIRT466997 SSRP1 structure specific recognition protein 1 2 4
MIRT468053 SIK1 salt inducible kinase 1 2 2
MIRT468146 SH3BP4 SH3 domain binding protein 4 2 2
MIRT468679 SEC24A SEC24 homolog A, COPII coat complex component 2 4
MIRT469085 RNF168 ring finger protein 168 2 2
MIRT469410 REL REL proto-oncogene, NF-kB subunit 2 6
MIRT471034 PISD phosphatidylserine decarboxylase 2 10
MIRT471491 PDE4D phosphodiesterase 4D 2 4
MIRT471951 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT472267 NFIC nuclear factor I C 2 2
MIRT472662 NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 2 4
MIRT474315 LAMC1 laminin subunit gamma 1 2 2
MIRT474833 KIAA0226 RUN and cysteine rich domain containing beclin 1 interacting protein 2 2
MIRT475064 IVNS1ABP influenza virus NS1A binding protein 2 6
MIRT475125 IPPK inositol-pentakisphosphate 2-kinase 2 2
MIRT475537 HOXA3 homeobox A3 2 8
MIRT475715 HEYL hes related family bHLH transcription factor with YRPW motif-like 2 2
MIRT476255 GNB1 G protein subunit beta 1 2 6
MIRT476272 GNAL G protein subunit alpha L 2 6
MIRT476695 FURIN furin, paired basic amino acid cleaving enzyme 2 2
MIRT477560 EIF1AX eukaryotic translation initiation factor 1A, X-linked 2 8
MIRT477844 DYRK3 dual specificity tyrosine phosphorylation regulated kinase 3 2 2
MIRT478907 CPSF7 cleavage and polyadenylation specific factor 7 2 6
MIRT479455 CDK6 cyclin dependent kinase 6 2 2
MIRT479987 CARD10 caspase recruitment domain family member 10 2 2
MIRT481182 AVL9 AVL9 cell migration associated 2 6
MIRT482114 AKT3 AKT serine/threonine kinase 3 2 4
MIRT482374 AGO2 argonaute 2, RISC catalytic component 2 2
MIRT482554 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 10
MIRT482577 ABHD2 abhydrolase domain containing 2 2 2
MIRT484773 ABCC6 ATP binding cassette subfamily C member 6 2 4
MIRT485219 PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha 2 8
MIRT487389 C10orf54 V-set immunoregulatory receptor 2 2
MIRT492710 PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 2 2
MIRT494351 CASKIN1 CASK interacting protein 1 2 2
MIRT495142 ZNRF1 zinc and ring finger 1 2 2
MIRT496014 CD180 CD180 molecule 2 2
MIRT497771 KIAA0895 KIAA0895 2 2
MIRT498979 ORC4 origin recognition complex subunit 4 2 8
MIRT499451 ODF2L outer dense fiber of sperm tails 2 like 2 8
MIRT499615 DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 2 8
MIRT500092 L2HGDH L-2-hydroxyglutarate dehydrogenase 2 8
MIRT500325 ZNF622 zinc finger protein 622 2 8
MIRT500419 ZMAT3 zinc finger matrin-type 3 2 4
MIRT500575 USP53 ubiquitin specific peptidase 53 2 2
MIRT500859 SYPL1 synaptophysin like 1 2 8
MIRT500937 SRPR SRP receptor alpha subunit 2 6
MIRT500955 SREK1 splicing regulatory glutamic acid and lysine rich protein 1 2 8
MIRT501087 SMAD7 SMAD family member 7 2 8
MIRT501501 PRICKLE2 prickle planar cell polarity protein 2 2 2
MIRT502041 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 2
MIRT502147 KIF5B kinesin family member 5B 2 8
MIRT502497 FAM122B family with sequence similarity 122B 2 8
MIRT502573 E2F7 E2F transcription factor 7 2 10
MIRT502645 DDX3X DEAD-box helicase 3, X-linked 2 8
MIRT502918 CDCA4 cell division cycle associated 4 2 8
MIRT502946 CDC37L1 cell division cycle 37 like 1 2 8
MIRT503142 ATG9A autophagy related 9A 2 6
MIRT504333 ASGR2 asialoglycoprotein receptor 2 2 6
MIRT504535 ZNF620 zinc finger protein 620 2 6
MIRT504851 HAUS3 HAUS augmin like complex subunit 3 2 6
MIRT505113 YTHDC1 YTH domain containing 1 2 6
MIRT505345 TMEM245 transmembrane protein 245 2 6
MIRT505395 TMEM100 transmembrane protein 100 2 2
MIRT505501 SRSF1 serine and arginine rich splicing factor 1 2 6
MIRT505550 SNX16 sorting nexin 16 2 6
MIRT505688 SESTD1 SEC14 and spectrin domain containing 1 2 6
MIRT505907 RIMS3 regulating synaptic membrane exocytosis 3 2 6
MIRT505925 RCAN3 RCAN family member 3 2 4
MIRT506107 PPIG peptidylprolyl isomerase G 2 6
MIRT506136 PLRG1 pleiotropic regulator 1 2 4
MIRT506165 PLAG1 PLAG1 zinc finger 2 8
MIRT506190 PHKA1 phosphorylase kinase regulatory subunit alpha 1 2 6
MIRT506485 MYO5A myosin VA 2 6
MIRT506857 KIF23 kinesin family member 23 2 6
MIRT506998 HNRNPDL heterogeneous nuclear ribonucleoprotein D like 2 6
MIRT507822 CDK1 cyclin dependent kinase 1 2 6
MIRT507849 CCNE2 cyclin E2 2 6
MIRT507878 CBX6 chromobox 6 2 2
MIRT508039 AXIN2 axin 2 2 6
MIRT508640 CASK calcium/calmodulin dependent serine protein kinase 2 5
MIRT509363 DMPK DM1 protein kinase 2 11
MIRT509689 ATAD5 ATPase family, AAA domain containing 5 2 4
MIRT510042 AKR1B10 aldo-keto reductase family 1 member B10 2 4
MIRT511846 GPATCH8 G-patch domain containing 8 2 4
MIRT512286 ARHGDIA Rho GDP dissociation inhibitor alpha 2 6
MIRT512641 CPEB3 cytoplasmic polyadenylation element binding protein 3 2 4
MIRT513858 JARID2 jumonji and AT-rich interaction domain containing 2 2 8
MIRT514019 CAMSAP1 calmodulin regulated spectrin associated protein 1 2 4
MIRT514046 ATG14 autophagy related 14 2 2
MIRT518090 TRIM35 tripartite motif containing 35 2 2
MIRT518529 FLCN folliculin 2 6
MIRT518993 NNT nicotinamide nucleotide transhydrogenase 2 4
MIRT521051 SLC2A3 solute carrier family 2 member 3 2 4
MIRT521202 SBNO1 strawberry notch homolog 1 2 6
MIRT521815 POM121C POM121 transmembrane nucleoporin C 2 2
MIRT522099 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 4
MIRT522774 LAMP2 lysosomal associated membrane protein 2 2 6
MIRT537818 EFNB2 ephrin B2 2 4
MIRT539898 RPL14 ribosomal protein L14 2 4
MIRT540842 GNAT1 G protein subunit alpha transducin 1 2 4
MIRT541218 HOXA10 homeobox A10 2 2
MIRT541433 CBX4 chromobox 4 2 2
MIRT542811 PHC3 polyhomeotic homolog 3 2 2
MIRT542838 PDCD1 programmed cell death 1 2 7
MIRT543058 BAZ2A bromodomain adjacent to zinc finger domain 2A 2 2
MIRT543078 APP amyloid beta precursor protein 2 2
MIRT543305 ZNF585B zinc finger protein 585B 2 2
MIRT543407 ANAPC13 anaphase promoting complex subunit 13 2 2
MIRT543524 PRSS21 protease, serine 21 2 2
MIRT543796 RALGAPB Ral GTPase activating protein non-catalytic beta subunit 2 4
MIRT543834 GSG1 germ cell associated 1 2 2
MIRT544570 POLDIP3 DNA polymerase delta interacting protein 3 2 2
MIRT544588 AP5Z1 adaptor related protein complex 5 zeta 1 subunit 2 4
MIRT544911 CLSPN claspin 2 2
MIRT544964 UGT2B4 UDP glucuronosyltransferase family 2 member B4 2 2
MIRT545185 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2 4
MIRT545346 CCDC83 coiled-coil domain containing 83 2 2
MIRT545681 DECR1 2,4-dienoyl-CoA reductase 1 2 2
MIRT545957 ZBTB10 zinc finger and BTB domain containing 10 2 2
MIRT545975 YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta 2 2
MIRT546113 USP48 ubiquitin specific peptidase 48 2 4
MIRT546609 SALL1 spalt like transcription factor 1 2 4
MIRT546620 RUNX1T1 RUNX1 translocation partner 1 2 2
MIRT546635 RTN4 reticulon 4 2 2
MIRT547067 PNISR PNN interacting serine and arginine rich protein 2 2
MIRT547134 PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2 2
MIRT547236 PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 2 4
MIRT547302 NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 2 2
MIRT547408 MKX mohawk homeobox 2 2
MIRT547459 MBD4 methyl-CpG binding domain 4, DNA glycosylase 2 2
MIRT547548 LRRFIP2 LRR binding FLII interacting protein 2 2 4
MIRT547664 KPNA3 karyopherin subunit alpha 3 2 2
MIRT547699 KPNA1 karyopherin subunit alpha 1 2 4
MIRT547969 HIGD1A HIG1 hypoxia inducible domain family member 1A 2 4
MIRT547998 HCFC2 host cell factor C2 2 4
MIRT548014 GRB2 growth factor receptor bound protein 2 2 4
MIRT548225 FKBP1A FK506 binding protein 1A 2 2
MIRT548278 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT548285 FASN fatty acid synthase 5 5
MIRT548730 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT548804 CLIP4 CAP-Gly domain containing linker protein family member 4 2 4
MIRT548944 CDK17 cyclin dependent kinase 17 2 2
MIRT549080 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT549122 C11orf24 chromosome 11 open reading frame 24 2 4
MIRT549279 ASH1L ASH1 like histone lysine methyltransferase 2 2
MIRT549386 AMOT angiomotin 2 2
MIRT550401 SLC29A1 solute carrier family 29 member 1 (Augustine blood group) 2 4
MIRT550465 OSCAR osteoclast associated, immunoglobulin-like receptor 2 4
MIRT550614 MTHFR methylenetetrahydrofolate reductase 2 2
MIRT550822 FAM229B family with sequence similarity 229 member B 2 2
MIRT551378 EPM2AIP1 EPM2A interacting protein 1 2 2
MIRT551616 ZNF267 zinc finger protein 267 2 2
MIRT551736 SSU72 SSU72 homolog, RNA polymerase II CTD phosphatase 2 2
MIRT552034 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT552343 ZNF704 zinc finger protein 704 2 2
MIRT552748 YRDC yrdC N6-threonylcarbamoyltransferase domain containing 2 2
MIRT553438 TPM3 tropomyosin 3 2 2
MIRT553560 TMEM161B transmembrane protein 161B 2 2
MIRT553619 TM7SF3 transmembrane 7 superfamily member 3 2 2
MIRT553771 TAF13 TATA-box binding protein associated factor 13 2 4
MIRT553808 SZRD1 SUZ RNA binding domain containing 1 2 4
MIRT554699 RNF149 ring finger protein 149 2 2
MIRT554961 RACGAP1 Rac GTPase activating protein 1 2 2
MIRT555031 RAB23 RAB23, member RAS oncogene family 2 2
MIRT555144 PTPRD protein tyrosine phosphatase, receptor type D 2 2
MIRT555224 PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 2 4
MIRT555274 PRDM4 PR/SET domain 4 2 2
MIRT555435 PPAP2B phospholipid phosphatase 3 2 2
MIRT556381 LURAP1L leucine rich adaptor protein 1 like 2 2
MIRT556858 KANK1 KN motif and ankyrin repeat domains 1 2 4
MIRT557280 HIST2H2BE histone cluster 2 H2B family member e 2 2
MIRT557479 GPR27 G protein-coupled receptor 27 2 4
MIRT558036 EXT1 exostosin glycosyltransferase 1 2 2
MIRT558512 CYP26B1 cytochrome P450 family 26 subfamily B member 1 2 4
MIRT558588 CREBL2 cAMP responsive element binding protein like 2 2 4
MIRT558659 CNKSR3 CNKSR family member 3 2 2
MIRT559008 CA8 carbonic anhydrase 8 2 2
MIRT559159 BTN3A3 butyrophilin subfamily 3 member A3 2 2
MIRT559530 ARHGAP12 Rho GTPase activating protein 12 2 4
MIRT560851 OSBPL3 oxysterol binding protein like 3 2 2
MIRT561148 KRT33B keratin 33B 2 2
MIRT561399 TUBB2A tubulin beta 2A class IIa 2 2
MIRT561873 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 2
MIRT562026 LANCL1 LanC like 1 2 2
MIRT562203 HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 2 2
MIRT562876 KIAA1456 KIAA1456 2 2
MIRT563085 SLC25A12 solute carrier family 25 member 12 2 2
MIRT563502 DLGAP3 DLG associated protein 3 2 2
MIRT563700 THRAP3 thyroid hormone receptor associated protein 3 2 2
MIRT563844 SMDT1 single-pass membrane protein with aspartate rich tail 1 2 2
MIRT563895 RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2 2
MIRT564331 CCNT1 cyclin T1 2 2
MIRT564477 ZNF391 zinc finger protein 391 2 2
MIRT564551 CCDC80 coiled-coil domain containing 80 2 2
MIRT564837 ZBTB16 zinc finger and BTB domain containing 16 2 2
MIRT564949 XKR7 XK related 7 2 2
MIRT564985 WNK3 WNK lysine deficient protein kinase 3 2 2
MIRT565045 VAV2 vav guanine nucleotide exchange factor 2 2 2
MIRT565395 TGFBR3 transforming growth factor beta receptor 3 2 2
MIRT566118 RASEF RAS and EF-hand domain containing 2 2
MIRT566649 NCKAP1 NCK associated protein 1 2 2
MIRT566830 MAP3K7 mitogen-activated protein kinase kinase kinase 7 2 2
MIRT567022 KLHL15 kelch like family member 15 2 2
MIRT567445 GNG12 G protein subunit gamma 12 2 2
MIRT567476 FZD9 frizzled class receptor 9 2 2
MIRT568020 CMTM4 CKLF like MARVEL transmembrane domain containing 4 2 2
MIRT568148 CCDC88C coiled-coil domain containing 88C 2 2
MIRT568473 ARMC12 armadillo repeat containing 12 2 2
MIRT568577 AHNAK2 AHNAK nucleoprotein 2 2 2
MIRT568620 ACVR2A activin A receptor type 2A 2 2
MIRT570467 TLK1 tousled like kinase 1 2 2
MIRT571118 UBE2H ubiquitin conjugating enzyme E2 H 2 2
MIRT571282 TTLL5 tubulin tyrosine ligase like 5 2 2
MIRT571427 RIF1 replication timing regulatory factor 1 2 2
MIRT571663 SERBP1 SERPINE1 mRNA binding protein 1 2 2
MIRT571827 PHF19 PHD finger protein 19 2 2
MIRT571930 LSM11 LSM11, U7 small nuclear RNA associated 2 2
MIRT574056 PROSC pyridoxal phosphate binding protein 2 2
MIRT574203 CLEC2D C-type lectin domain family 2 member D 2 2
MIRT574540 PDIA6 protein disulfide isomerase family A member 6 2 4
MIRT574593 N4BP1 NEDD4 binding protein 1 2 2
MIRT575881 Cask calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2 4
MIRT575923 Dmpk dystrophia myotonica-protein kinase 2 7
MIRT576101 Pdcd1 programmed cell death 1 2 5
MIRT576592 Npepps aminopeptidase puromycin sensitive 2 2
MIRT614699 TRAK1 trafficking kinesin protein 1 2 2
MIRT616466 ADRA2B adrenoceptor alpha 2B 2 2
MIRT618895 ANKMY1 ankyrin repeat and MYND domain containing 1 2 2
MIRT621497 GPRC5A G protein-coupled receptor class C group 5 member A 2 4
MIRT640537 C3orf36 chromosome 3 open reading frame 36 2 2
MIRT645509 BSPRY B-box and SPRY domain containing 2 2
MIRT646594 ANKRD36 ankyrin repeat domain 36 2 2
MIRT648783 KLHL40 kelch like family member 40 2 2
MIRT655811 NOTCH2 notch 2 2 2
MIRT658792 EIF2B2 eukaryotic translation initiation factor 2B subunit beta 2 2
MIRT659255 CUL3 cullin 3 2 2
MIRT680981 DCAF17 DDB1 and CUL4 associated factor 17 2 2
MIRT682283 RS1 retinoschisin 1 2 2
MIRT682513 GLP2R glucagon like peptide 2 receptor 2 2
MIRT691708 FLOT2 flotillin 2 2 2
MIRT693929 HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2 2 2
MIRT698081 TPM1 tropomyosin 1 2 2
MIRT701505 NEGR1 neuronal growth regulator 1 2 2
MIRT702091 MCFD2 multiple coagulation factor deficiency 2 2 2
MIRT702880 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT713418 SLC35E2B solute carrier family 35 member E2B 2 2
MIRT714437 ARHGAP32 Rho GTPase activating protein 32 2 2
MIRT716431 RAB15 RAB15, member RAS oncogene family 2 2
MIRT717460 ADORA3 adenosine A3 receptor 2 2
MIRT720150 PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 2 2
MIRT725131 SYNRG synergin gamma 2 2
MIRT731965 KCNN4 potassium calcium-activated channel subfamily N member 4 3 1
MIRT733328 KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding) 2 0
MIRT733577 Smurf2 SMAD specific E3 ubiquitin protein ligase 2 3 0
MIRT733856 MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) 4 0
MIRT734386 SMAD2 SMAD family member 2 2 1
MIRT734389 MAPK3 mitogen-activated protein kinase 3 2 1
MIRT734798 BCL2L2 BCL2 like 2 3 0
MIRT735175 CASC9 cancer susceptibility 9 (non-protein coding) 2 0
MIRT736699 AFAP1 actin filament associated protein 1 3 0
MIRT736717 EMX1 empty spiracles homeobox 1 3 0
MIRT737341 LINC00473 long intergenic non-protein coding RNA 473 3 0
MIRT756126 SNHG25 small nucleolar RNA host gene 25 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-497 Bufalin NULL 9547215 Quantitative real-time PCR colorectal cancer HCT116 cells 24375248 2014 up-regulated
miR-497 Diethylstilbestrol approved 448537 Microarray mammosphere-derived epithelial cells (MDEC) 19549897 2009 up-regulated
miR-497 Ethanol NULL 702 Quantitative real-time PCR CIE10 22141737 2012 up-regulated
miR-497 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 up-regulated
miR-497 Reversine NULL 210332 Microarray C2C12 myoblast cells 24513286 2014 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-497 Tamoxifen 2733525 NSC180973 approved sensitive Low Breast Cancer cell line (MCF-7, T47D)
hsa-mir-497 Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-mir-497 Paclitaxel 36314 NSC125973 approved resistant cell line (W1)
hsa-mir-497 Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-mir-497 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-mir-497 Androstenedione+Letrozole sensitive cell line (MCF-7)
hsa-mir-497 Tamoxifen 2733525 NSC180973 approved sensitive cell line (MCF7)
hsa-mir-497 Cisplatin 5460033 NSC119875 approved sensitive cell line (BxPC3)
hsa-miR-497-5p (11E)-11-(4-aminobutylidene)-15,16-dimethoxy-20-methyl-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaen-19-one 45027844 NSC727621 resistant
hsa-miR-497-5p (11E)-15,16-dimethoxy-20-methyl-11-[3-(methylamino)propylidene]-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaen-19-one 45027834 NSC727048 resistant
hsa-miR-497-5p (1R,12S)-20-[2-(dimethylamino)ethyl]-15,16-dimethoxy-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-2,4(8),9,13,15,17-hexaene-11,19-dione 45027831 NSC726770 resistant
hsa-miR-497-5p (1r,2s,4s,8r,9s,10r,14r,15s)-9-hydroxy-2,14-diiodo-1,10,14-trimethyl-5-methylidene-7,18-dioxatricyclo[13.2.1.04,8]octadecan-6-one 6712557 NSC697264 resistant
hsa-miR-497-5p (1Z)-2-anilino-N-[(5-carbamoyl-1H-imidazol-4-yl)amino]-2-oxoethanimidoyl cyanide 5466279 NSC683605 resistant
hsa-miR-497-5p (2E,5Z)-2-[(5-acetyl-4-methyl-1,3-thiazol-2-yl)hydrazinylidene]-5-[(2-methoxyphenyl)methylidene]-1,3-thiazolidin-4-one 135472679 NSC658292 sensitive
hsa-miR-497-5p (2R)-2-(1H-benzimidazol-2-yl)-2-(2-chloro-6-methylpyrimidin-4-yl)acetonitrile 390694 NSC688326 resistant
hsa-miR-497-5p (2s,3s,7as)-3-hydroxy-2-[(e)-prop-1-enyl]-2,3,7,7a-tetrahydrofuro[3,4-b]pyran-5-one 24202877 NSC726146 resistant
hsa-miR-497-5p (3-sulfanylidene-5,6-dihydroimidazo[2,1-c][1,2,4]thiadiazol-7-yl) 2-[[4-(trifluoromethoxy)phenyl]sulfonylamino]-4,5-dihydroimidazole-1-carbodithioate 24205510 NSC736065 sensitive
hsa-miR-497-5p (3e)-3-[(2-chloro-5-methoxy-1h-indol-3-yl)methylidene]-1-phenylindol-2-one 5471475 NSC711615 sensitive
hsa-miR-497-5p (3R,5R,8R,9S,10S,13R,14S,17R)-17-[(2R)-4-(4,5-dihydro-1H-imidazol-2-yl)butan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 391085 NSC689620 resistant
hsa-miR-497-5p (3z)-6,7-dichloro-3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-1h-indol-2-one 45486324 NSC748498 sensitive
hsa-miR-497-5p (4-butanoyloxythieno[2,3-f][1]benzothiol-8-yl) butanoate 388304 NSC682994 sensitive
hsa-miR-497-5p (4-chlorophenyl) 3-methyl-5-nitroimidazole-4-sulfonate 236063 NSC38086 resistant
hsa-miR-497-5p (4aS,4bR,10bS,12aS)-2-butyl-12a-methyl-8-(2-pyrrolidin-1-ylethoxy)-4,4a,4b,5,6,10b,11,12-octahydronaphtho[2,1-f]isoquinoline-1,3-dione 383426 NSC671765 resistant
hsa-miR-497-5p (4e)-2-(2-hydroxybenzoyl)-5-methyl-4-[(3,4,5-trimethoxyphenyl)methylene]pyrazol-3-one 5467421 NSC652182 sensitive
hsa-miR-497-5p (4z)-4-[[4-(dimethylamino)phenyl]methylidene]-1-methyl-2-phenylpyrazolo[1,5-a]indol-1-ium-6-ol;trifluoromethanesulfonate 5469862 NSC693573 sensitive
hsa-miR-497-5p (7-acetamido-2-acetyloxy-1-methoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-3-yl) acetate 435732 NSC374980 sensitive
hsa-miR-497-5p (e)-1-(benzenesulfonyl)-3-(2-phenyl-1h-indol-3-yl)prop-2-en-1-one 54613416 NSC749193 sensitive
hsa-miR-497-5p (e)-1-[3-[(4,6-dianilino-1,3,5-triazin-2-yl)amino]phenyl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one 45028636 NSC743530 sensitive
hsa-miR-497-5p (E)-1-[3,5-bis[(dimethylamino)methyl]-4-hydroxyphenyl]-3-(4-nitrophenyl)prop-2-en-1-one 5838541 NSC681129 resistant
hsa-miR-497-5p (e)-1-[4-[[4-(4-chloroanilino)-6-(4-fluoroanilino)-1,3,5-triazin-2-yl]amino]phenyl]-3-[4-(dimethylamino)phenyl]prop-2-en-1-one 45028715 NSC743884 sensitive
hsa-miR-497-5p (e)-1-[4-[[4,6-bis(4-fluoroanilino)-1,3,5-triazin-2-yl]amino]phenyl]-3-(furan-2-yl)prop-2-en-1-one 24205907 NSC737226 sensitive
hsa-miR-497-5p (E)-3-(3,4-dihydroxyphenyl)-N-[(13S)-3-methoxy-13-methyl-8,9,11,12,14,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]prop-2-enamide 24205536 NSC736118 resistant
hsa-miR-497-5p (Z)-(4-butoxycarbonylpiperazin-1-yl)-(2,4-dinitrophenoxy)imino-oxidoazanium 11495269 NSC731701 resistant
hsa-miR-497-5p (Z)-2-amino-3-[[4-[2-(methoxymethyl)pyrrolidin-1-yl]phenyl]methylideneamino]but-2-enedinitrile 24206055 NSC737799 resistant
hsa-miR-497-5p (Z)-3-amino-1-(5-amino-3-phenylpyrazol-1-yl)-3-phenylprop-2-en-1-one 21825201 NSC749518 sensitive
hsa-miR-497-5p [(3S,8R,9S,10R,13S,14S,16E,17S)-17-acetyloxy-16-[[3-methoxy-4-(2-piperidin-1-ylethoxy)phenyl]methylidene]-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,17-dodecahydrocyclopenta[a]phenanthren-3-yl] acetate 24204032 NSC730473 resistant
hsa-miR-497-5p [(8R,9S,13S,14S)-2-ethoxy-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] [(8S,9R,13R,14R)-2-ethoxy-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] sulfite;ethyl acetate 389907 NSC686560 sensitive
hsa-miR-497-5p [1-(4-butylphenyl)-2,5-dimethyl-4-(methylcarbamoyloxymethyl)pyrrol-3-yl]methyl N-methylcarbamate 321869 NSC276361 resistant
hsa-miR-497-5p [1-[(2-bromo-5-hydroxy-4-methoxyphenyl)methyl]spiro[1,3,4,5,7,8-hexahydroisoquinoline-6,2'-1,3-dioxolane]-2-yl]-cyclobutylmethanone 401792 NSC715522 sensitive
hsa-miR-497-5p [10-[2-(diethylamino)ethylamino]-8-oxo-1,14,15-triazatetracyclo[7.6.1.02,7.013,16]hexadeca-2(7),3,5,9,11,13(16),14-heptaen-5-yl] acetate 439026 NSC699152 resistant
hsa-miR-497-5p [3-(4-fluorophenyl)-8,9-dimethyl-2-oxo-5H-pyrano[3,2-c]chromen-5-yl] acetate 45113107 NSC747825 sensitive
hsa-miR-497-5p [3,4,5-tris(2,2-dimethylpropanoyloxy)-6-[(2S)-4-hydroxybutan-2-yl]oxyoxan-2-yl]methyl 2,2-dimethylpropanoate 389870 NSC686498 resistant
hsa-miR-497-5p [6-[(E)-(carbamothioylhydrazinylidene)methyl]pyridin-3-yl] acetate 9555726 NSC144055 sensitive
hsa-miR-497-5p 1-(4-methoxyphenyl)-3-[(z)-1-[6-[(z)-n-[(4-methoxyphenyl)carbamothioylamino]-c-methylcarbonimidoyl]pyridin-2-yl]ethylideneamino]thiourea 6375828 NSC668486 resistant
hsa-miR-497-5p 1-(4,8-dioxothieno[2,3-f][1]benzothiol-2-yl)ethyl acetate 388025 NSC682450 sensitive
hsa-miR-497-5p 1-[(z)-(4-methoxyphenyl)methylideneamino]-3-naphthalen-1-ylurea 5914027 NSC680934 sensitive
hsa-miR-497-5p 1-[(z)-(5-chloro-2-hydroxyphenyl)methylideneamino]-3-[(e)-(5-chloro-2-hydroxyphenyl)methylideneamino]thiourea 135460243 NSC65022 resistant
hsa-miR-497-5p 1-[(z)-1-[6-[(z)-c-methyl-n-(phenylcarbamothioylamino)carbonimidoyl]pyridin-2-yl]ethylideneamino]-3-phenylthiourea 6374206 NSC668482 resistant
hsa-miR-497-5p 1-[4-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]butyl]-5,10-dihydroxynaphtho[2,3-f]indole-4,11-dione 406508 NSC724635 resistant
hsa-miR-497-5p 1-[5-[[[4-chlorobutyl(methyl)amino]-[(5-nitrofuran-2-yl)methoxy]phosphoryl]oxymethyl]-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione 404846 NSC721390 sensitive
hsa-miR-497-5p 1-[7-methyl-8-(3,4,5-trimethoxyphenyl)-7,8-dihydro-6h-[1,3]dioxolo[4,5-g]chromen-6-yl]piperazine 384846 NSC675364 sensitive
hsa-miR-497-5p 1-[phenyl(2-pyridinyl)methylene]-4-(2-methylphenyl)thiosemicarbazide 6148953 NSC668326 resistant
hsa-miR-497-5p 10,16-bis[2-(dimethylamino)ethyl]-5-hydroxy-1,9,10,16-tetrazapentacyclo[9.6.2.02,7.08,19.014,18]nonadeca-2(7),3,5,8,11(19),12,14(18)-heptaene-15,17-dione 399631 NSC710548 resistant
hsa-miR-497-5p 15-[2-(dimethylamino)ethyl]-10-[2-(dimethylamino)ethylamino]-5-methoxy-1,15-diazatetracyclo[7.7.1.02,7.013,17]heptadeca-2(7),3,5,9,11,13(17)-hexaene-8,14,16-trione;hydrochloride 392061 NSC691851 resistant
hsa-miR-497-5p 1h-indole, 5-bromo-3-[2-(2-pyridinyl)-4-thiazolyl]- 397551 NSC705871 resistant
hsa-miR-497-5p 2-(2-benzoylbenzimidazol-1-yl)-1-(4-fluorophenyl)ethanone 45029093 NSC745451 sensitive
hsa-miR-497-5p 2-(2-chlorophenyl)-3-[5-(1,2,4-triazol-4-ylmethyl)-1,3,4-oxadiazol-2-yl]-1,3-thiazolidin-4-one 45029357 NSC746513 sensitive
hsa-miR-497-5p 2-(2-hydroxyphenyl)-3-[2-[2-(2-hydroxyphenyl)-4-oxo-1,3-thiazolidin-3-yl]-[1,3]thiazolo[5,4-f][1,3]benzothiazol-6-yl]-1,3-thiazolidin-4-one 398513 NSC708424 sensitive
hsa-miR-497-5p 2-(3-ethoxy-4-hydroxyphenyl)-3-[2-[2-(3-ethoxy-4-hydroxyphenyl)-4-oxo-1,3-thiazolidin-3-yl]-[1,3]thiazolo[5,4-f][1,3]benzothiazol-6-yl]-1,3-thiazolidin-4-one 398511 NSC708422 sensitive
hsa-miR-497-5p 2-(3,5-di-tert-butyl-4-methoxybenzyl)cyclopent-4-ene-1,3-dione 403662 NSC718730 resistant
hsa-miR-497-5p 2-(furan-2-yl)-5-phenyl-1h-pyrazolo[1,5-a]pyrimidin-7-one 342597 NSC379651 sensitive
hsa-miR-497-5p 2-(hydroxymethyl)-5-[6-(2-propan-2-ylidenehydrazinyl)purin-9-yl]oxolane-3,4-diol 60147745 NSC752330 resistant
hsa-miR-497-5p 2-(hydroxymethyl)-5-[6-[(e)-2-hydroxy-2-phenylethenyl]purin-9-yl]oxolane-3,4-diol 135476744 NSC295272 resistant
hsa-miR-497-5p 2-(naphthalen-2-ylamino)-1,2-diphenylethanone 411561 NSC34924 sensitive
hsa-miR-497-5p 2-[(z)-6-(2-fluorophenyl)hex-3-en-1,5-diynyl]aniline 24204954 NSC733691 sensitive
hsa-miR-497-5p 2-[[1-[[(1r,4s,5r,8s,9r,10s,12r,13r)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]-3-[[(1r,4s,5r,8s,9r,10s,13r)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[ 45027898 NSC735846 resistant
hsa-miR-497-5p 2-[[5-methoxy-2-(4-methoxyphenyl)-1h-indol-3-yl]methylidene]propanedinitrile 44435255 NSC749028 sensitive
hsa-miR-497-5p 2-[[6-[[bis(carboxymethyl)amino]methyl]-4-[2-[4-(2-phenylethynyl)phenyl]ethynyl]pyridin-2-yl]methyl-(carboxymethyl)amino]acetic acid 369524 NSC641379 resistant
hsa-miR-497-5p 2-[2-[(z)-1-benzamido-2-(2-hydroxyphenyl)vinyl]-5-oxo-oxazolidin-4-yl]acetic acid 6477540 NSC686413 sensitive
hsa-miR-497-5p 2-[4-[5-[2,6-dimethoxy-4-[5-(3,4,5-trimethoxyphenyl)-4,5-dihydro-1,2-oxazol-3-yl]phenoxy]pentoxy]-3-methoxyphenyl]-2,3-dihydro-1H-quinazolin-4-one 45029290 NSC746035 sensitive
hsa-miR-497-5p 2-hydroxy-N-[(E)-1-[6-[(E)-N-[(2-hydroxybenzoyl)amino]-C-methylcarbonimidoyl]pyridin-2-yl]ethylideneamino]benzamide 5779747 NSC617573 resistant
hsa-miR-497-5p 2-isonicotinoyl-5-methyl-4-(2-naphthyldiazenyl)-2,4-dihydro-3h-pyrazol-3-one 327703 NSC303769 sensitive
hsa-miR-497-5p 2-methoxy-5,7,8,13,13a,14-hexahydroisoquino[3,2-b][3]benzazepine 392606 NSC693146 resistant
hsa-miR-497-5p 2-methyl-4,4-diphenyl-1,4-benzoxaphosphinin-4-ium;bromide 24199840 NSC346098 sensitive
hsa-miR-497-5p 2-phenyl-6-((1-phenyl-1h-tetraazol-5-yl)oxy)-4h-chromen-4-one 386037 NSC677603 sensitive
hsa-miR-497-5p 2,3-dibenzoyloxy-4-hydroxy-4-oxobutanoate;(2,5-dimethylphenyl)-(4-methylphenyl)-phenylsulfanium 5351228 NSC116693 sensitive
hsa-miR-497-5p 2,3-dimethoxy-5-[(E)-3,7,11,15-tetramethylhexadec-2-enyl]sulfanylcyclohexa-2,5-diene-1,4-dione 5476942 NSC276371 sensitive
hsa-miR-497-5p 2,4-diethoxyestra-1,3,5(10)trien-3,17.beta.-diol 388044 NSC682505 sensitive
hsa-miR-497-5p 2,5,12-trimethyl-[1,4]benzodioxino[3,2-g]isoquinolin-2-ium acetate 388316 NSC683048 sensitive
hsa-miR-497-5p 2,6-bis[1-(3-ethylthioureidoimino)ethyl]pyridine 6393657 NSC668337 resistant
hsa-miR-497-5p 3-(3-fluorophenyl)-n-pyridin-3-yl-2h-pyrazolo[3,4-d][1,3]thiazol-5-amine 60147811 NSC752461 sensitive
hsa-miR-497-5p 3-(3,5-dichlorophenyl)-2-(2-pyridinyl)acrylonitrile 5467799 NSC659323 sensitive
hsa-miR-497-5p 3-(4-bromophenyl)-4-methyl-8-pyrrolidin-1-yl-8H-thieno[2,3-b]pyrrolizin-4-ium;iodide 388536 NSC683517 sensitive
hsa-miR-497-5p 3-(4-chlorophenyl)thieno[2,3-b]pyrrolizin-8-one 388525 NSC683509 sensitive
hsa-miR-497-5p 3-(4-fluorophenyl)-4-(4-methoxyphenyl)-6-(4-pyridyl)pyridin-2-amine 388617 NSC683628 resistant
hsa-miR-497-5p 3-(4-methoxyphenyl)-1-[(e)-2-(2-thienyl)vinyl]pyrazino[1,2-a]benzimidazole 5471218 NSC709480 sensitive
hsa-miR-497-5p 3-(4-methoxyphenyl)-3,3a,4,5-tetrahydro-2h-benzo[g]indazole 21792363 NSC744693 sensitive
hsa-miR-497-5p 3-(4-methoxyphenyl)-4-methyl-8-pyrrolidin-1-yl-8H-thieno[2,3-b]pyrrolizin-4-ium;iodide 388538 NSC683518 sensitive
hsa-miR-497-5p 3-(9-amino-4-methoxy-6-methyl-7,8-dihydro-5h-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6,7-dimethoxy-3h-2-benzofuran-1-one;hydrochloride 45028024 NSC740642 sensitive
hsa-miR-497-5p 3-[(e)-1-(2-hydroxy-4-methoxy-phenyl)ethylideneamino]-1,1-dimethyl-thiourea 135493996 NSC689547 resistant
hsa-miR-497-5p 3-[1-(1,3-benzothiazol-2-yl)-3-chloro-6-methyl-2-oxo-1,7,8-triazaspiro[3.4]oct-6-en-8-yl]benzenesulfonic acid 397240 NSC704657 resistant
hsa-miR-497-5p 3-[4-(6-methoxy-1H-benzimidazol-2-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazole 118624714 NSC761814 sensitive
hsa-miR-497-5p 3-methyl-4-methylsulfanyl-5-phenyl-6h-pyrazolo[3,4-c]pyrazole 135450457 NSC692021 resistant
hsa-miR-497-5p 3-N',5-N'-bis(2-hydroxybenzoyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbohydrazide 377030 NSC658247 sensitive
hsa-miR-497-5p 3-phenacyliden-5-brom-2-indolinon 5351299 NSC294961 resistant
hsa-miR-497-5p 3,25-dioxa-11,14,17,31-tetrazatetracyclo[25.3.1.04,9.019,24]hentriaconta-1(31),4,6,8,10,17,19,21,23,27,29-undecaene 388222 NSC682815 sensitive
hsa-miR-497-5p 3,4-diphenylisoxazolo[3,4-d]pyridazin-7(6h)-one 54613569 NSC749505 sensitive
hsa-miR-497-5p 3,5,12,14-tetrabutyl-7,10-dithia-8,9-diselena-3,5,12,14-tetrazatricyclo[9.3.0.02,6]tetradeca-1(11),2(6)-diene-4,13-diselone 395765 NSC700584 resistant
hsa-miR-497-5p 4-(3-(4-((2,2-dimethylpropanoyl)oxy)phenyl)acryloyl)phenyl pivalate 5468262 NSC666765 sensitive
hsa-miR-497-5p 4-(3h-[1,3]thiazolo[3,4-a]benzimidazol-1-yl)phenyl acetate 384820 NSC675272 sensitive
hsa-miR-497-5p 4-(4-fluorophenyl)-2-[8-[[4-(4-fluorophenyl)-5-propyl-1h-imidazol-2-yl]sulfanyl]octylsulfanyl]-5-propyl-1h-imidazole;methanesulfonic acid 374589 NSC652562 sensitive
hsa-miR-497-5p 4-(dimethylamino)-9-ethyl-16-methyl-4,20-diazapentacyclo[11.7.0.02,6.07,12.014,19]icosa-1(13),14(19),15,17-tetraene-3,5-dione 397883 NSC706739 sensitive
hsa-miR-497-5p 4-[(4-methyl-1,2-oxazol-5-yl)amino]naphthalene-1,2-dione 384244 NSC673785 sensitive
hsa-miR-497-5p 4-[(6-chloro-4h-1,3-benzodioxin-8-yl)methylsulfanyl]pyrrolo[1,2-a]quinoxaline 331156 NSC321491 sensitive
hsa-miR-497-5p 4-[2-(11h-indolo[3,2-c]quinolin-6-ylamino)ethyl]benzene-1,2-diol 24205774 NSC736609 resistant
hsa-miR-497-5p 4-[4-(diethylamino)phenyl]-2-(4-hydroxypiperidin-1-yl)-6-(3,4,5-trimethoxyphenyl)pyridine-3-carbonitrile 60148088 NSC753601 resistant
hsa-miR-497-5p 4-[4,6-bis(methylsulfanyl)pyrazolo[3,4-d]pyrimidin-1-yl]-7-chloroquinoline 24203467 NSC728188 sensitive
hsa-miR-497-5p 4-methoxy-2,6-bis[hydroxy(methyl)amino]-1,3,5-triazine 46191705 NSC749909 resistant
hsa-miR-497-5p 4,4-dibromo-1-(3-bromo-4-methylpentyl)cyclopentene 382925 NSC670802 resistant
hsa-miR-497-5p 4,8-dioxothieno[3,2-f][1]benzothiole-2-carboxylic acid 375906 NSC656243 sensitive
hsa-miR-497-5p 5-[(E)-[(3aR,6S,6aR)-6-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxol-4-ylidene]-(3,4,5-trimethoxyphenyl)methyl]-2-methoxyphenol 54576090 NSC753427 sensitive
hsa-miR-497-5p 5-[(E)-3-[4-(diethylamino)phenyl]prop-2-enylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione 6376062 NSC684567 sensitive
hsa-miR-497-5p 5-amino-3-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6h-triazolo[4,5-d]pyrimidin-7-one 135454027 NSC89822 resistant
hsa-miR-497-5p 5-chroman-6-yl-2-(4-pyridyl)oxazole 380226 NSC665702 sensitive
hsa-miR-497-5p 5-fluoranyl-7-nitro-quinolin-8-ol 260644 NSC92207 resistant
hsa-miR-497-5p 5-methyl-2-{[(2)-3-phenylprop-2-enoyl]amino}benzamide 53329052 NSC748147 sensitive
hsa-miR-497-5p 5-methylphenanthroline 72791 NSC4272 resistant
hsa-miR-497-5p 5-phenyl-2,3-bis(2-thienyl)thiophene 395510 NSC700200 sensitive
hsa-miR-497-5p 6-(1,5-dimethyl-3-oxo-hexyl)-4,8a-dimethyl-1,4a,5,6,7,8-hexahydronaphthalen-2-one 390517 NSC687958 resistant
hsa-miR-497-5p 6-(11-aminoundecyl)indeno[1,2-c]isoquinoline-5,11-dione;hydrochloride 16221323 NSC740510 resistant
hsa-miR-497-5p 6-(4-acetylanilino)-9-methoxyindeno[1,2-c]quinolin-11-one 24205210 NSC734628 sensitive
hsa-miR-497-5p 6-[(2e)-2-(4-fluorophenyl)-2-hydroxyiminoethoxy]-2-phenylchromen-4-one 24203680 NSC729146 sensitive
hsa-miR-497-5p 6-[2-[2-[2-(5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)ethylamino]ethylamino]ethyl]indeno[1,2-c]isoquinoline-5,11-dione;2,2,2-trifluoroacetic acid 45027833 NSC726973 resistant
hsa-miR-497-5p 6-[3-[2-[3-(5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)propylamino]ethylamino]propyl]indeno[1,2-c]isoquinoline-5,11-dione;2,2,2-trifluoroacetic acid 45027830 NSC726767 resistant
hsa-miR-497-5p 6-[3-[3-[3-(5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)propylamino]propylamino]propyl]indeno[1,2-c]isoquinoline-5,11-dione 11520588 NSC727357 resistant
hsa-miR-497-5p 6-benzyl-3,8,9-trimethoxy-11-methyl-6,11-dihydro-5h-indeno[1,2-c]isoquinolin-5-one 373164 NSC649107 sensitive
hsa-miR-497-5p 6-bromochroman-2-one 266737 NSC105509 sensitive
hsa-miR-497-5p 6-butyl-12-methyl-5,6-dihydrobenzimidazolo[2,1-a]isoquinolin-7-ium-3,10-diol;6-butyl-12-methyl-5,6-dihydrobenzimidazolo[2,1-a]isoquinolin-12-ium-3,9-diol;diiodide 403475 NSC718370 sensitive
hsa-miR-497-5p 6,6-dimethyl-2,10-dimethylidene-4,8-dioxadispiro[4.1.47.35]tetradecane-3,9-dione 318804 NSC258625 resistant
hsa-miR-497-5p 7'-but-3-en-2-yl-7'-(3-phenylmethoxypropyl)spiro[1,3-dioxolane-2,2'-3,4,7a,8,9,10-hexahydro-1h-cyclopenta[i]indolizine]-6'-thione 361486 NSC624523 sensitive
hsa-miR-497-5p 7jx 384175 NSC673499 sensitive
hsa-miR-497-5p 8-azadenosine 251928 NSC72961 resistant
hsa-miR-497-5p 9-[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]anilino]-n-(2-hydroxyethyl)acridine-4-carboxamide 384527 NSC674498 resistant
hsa-miR-497-5p A15655 262000 NSC95170 sensitive
hsa-miR-497-5p Abiraterone 132971 NSC749226 approved sensitive
hsa-miR-497-5p Abiraterone 132971 NSC749226 approved sensitive
hsa-miR-497-5p Acetic acid;4-(2-aminocyclohexyl)imino-2-methylbenzo[f][1,3]benzoxazol-9-one 388014 NSC682436 sensitive
hsa-miR-497-5p Aklavin 264889 NSC100290 resistant
hsa-miR-497-5p Alvocidib 5287969 NSC649890 resistant
hsa-miR-497-5p Amonafide 50515 NSC308847 resistant
hsa-miR-497-5p Ao-267/15176074 393944 NSC696916 resistant
hsa-miR-497-5p Arylpurines 24205955 NSC737430 resistant
hsa-miR-497-5p Basic yellow k 7081 NSC13973 resistant
hsa-miR-497-5p Benzyl n-[5-[(2-methylpropan-2-yl)oxycarbonylamino]-6-[2-[[4-[2-[[2-[(2-methylpropan-2-yl)oxycarbonylamino]-6-(phenylmethoxycarbonylamino)hexanoyl]amino]ethylamino]-9,10-dioxoanthracen-1-yl]amino]ethy 438923 NSC684439 sensitive
hsa-miR-497-5p Berberine iodide 72350 NSC150446 sensitive
hsa-miR-497-5p Bindschedler's green 73516 NSC7811 sensitive
hsa-miR-497-5p Butanedioic acid;10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine 5351168 NSC46061 resistant
hsa-miR-497-5p Centaureidin 5315773 NSC106969 sensitive
hsa-miR-497-5p Cinnoline, 4-nitro-, 1-oxide 100397 NSC294846 resistant
hsa-miR-497-5p Destruxin b NSC236580 resistant
hsa-miR-497-5p Diaziridinone, bis(.alpha.,.alpha.-dimethylphenethyl)- 391928 NSC691608 resistant
hsa-miR-497-5p Diethyl 5,10-dioxobenzo[g]quinoxaline-2,3-dicarboxylate 400766 NSC713197 sensitive
hsa-miR-497-5p Diethyl(acetylamino)[(6-nitro-1h-indol-3-yl)methyl]propanedioate 249442 NSC67774 sensitive
hsa-miR-497-5p Dihydrorotenone 243725 NSC53866 sensitive
hsa-miR-497-5p Edelfosine 1392 NSC324368 resistant
hsa-miR-497-5p Ethyl 2-((4-(6-bromo-2-methyl-4-oxo-3(4h)-quinazolinyl)phenyl)hydrazono)-3-oxobutanoate 135494008 NSC691085 sensitive
hsa-miR-497-5p Ethyl 5-amino-4-(3,4-dihydro-2h-1,5-benzodioxepin-7-ylamino)-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxylate 399955 NSC711107 sensitive
hsa-miR-497-5p From combretum caffrum plant 5386397 NSC609397 sensitive
hsa-miR-497-5p Hexadecyl-(2-hydroxyethyl)-(1H-imidazol-5-ylmethyl)-methylazanium;chloride 21144688 NSC265875 resistant
hsa-miR-497-5p Hsdb 8106 16129719 NSC676825 resistant
hsa-miR-497-5p Hx-0835 5471280 NSC710264 sensitive
hsa-miR-497-5p Ilmofosine 55008 NSC601679 resistant
hsa-miR-497-5p Ixabepilone 6445540 NSC747973 sensitive
hsa-miR-497-5p J-400634 385621 NSC676944 resistant
hsa-miR-497-5p Justicidin b 122805 NSC254665 resistant
hsa-miR-497-5p Kikubasaponin 500377 NSC698792 resistant
hsa-miR-497-5p L-cysteine, s-[(4-chlorophenyl)diphenylmethyl]- 275977 NSC123138 sensitive
hsa-miR-497-5p L-lys-l-p-no2phe-l-ala-l-p-no2phenh2 386384 NSC678355 resistant
hsa-miR-497-5p Lomondomycin 135426834 NSC156939 sensitive
hsa-miR-497-5p Massoia lactone 39914 NSC720841 resistant
hsa-miR-497-5p Methyl (1s,10r)-6-methyl-10-nonyl-7,9,12-triazatricyclo[6.3.1.04,12]dodeca-5,8-diene-5-carboxylate 401693 NSC715423 sensitive
hsa-miR-497-5p Methyl (Z)-4,4-dicyano-4-[(3-methoxyphenyl)methylideneamino]but-2-enoate 5470182 NSC698278 resistant
hsa-miR-497-5p Methyl 10-oxo-3,13,23-triazahexacyclo[11.10.1.02,11.04,9.014,19.020,24]tetracosa-1(24),2(11),4,6,8,14,16,18,20,22-decaene-22-carboxylate 45028277 NSC742037 sensitive
hsa-miR-497-5p Methyl 11h-pyrido[2,3-a]carbazole-5-carboxylate 13776879 NSC740203 sensitive
hsa-miR-497-5p Methyl 2-(2,3-dihydro-1H-inden-5-ylmethyl)-1-oxo-3,6,7,8-tetrahydro-as-indacene-2-carboxylate 385670 NSC677016 sensitive
hsa-miR-497-5p Methyl 2-[33,34,35,36-tetrahydroxy-11,19,27-tris(2-methoxy-2-oxoethyl)-7,15,23,31-tetramethyl-3,11,19,27-tetrazapentacyclo[27.3.1.15,9.113,17.121,25]hexatriaconta-1(32),5,7,9(36),13,15,17(35),21(34),2 395595 NSC700325 resistant
hsa-miR-497-5p Methyl 4-[[3-chloro-4-(3-chloro-2-methylanilino)-2,5-dioxopyrrol-1-yl]methyl]benzoate 1179905 NSC732800 resistant
hsa-miR-497-5p Methyl 4-[3-(2-thienyl)quinoxalin-2-yl]oxybenzoate 388002 NSC682365 sensitive
hsa-miR-497-5p Miltefosin c 3599 NSC605583 resistant
hsa-miR-497-5p N'-(2-hydroxy-5-(hydroxy(oxido)amino)benzylidene)-1-piperidinecarbothiohydrazide 135484941 NSC689530 resistant
hsa-miR-497-5p N'-[2-(1,3-benzoxazol-2-ylamino)-6-methylpyrimidin-4-yl]-2-hydroxybenzohydrazide 24205702 NSC736401 resistant
hsa-miR-497-5p N'-[8-(4-hydroxy-3,5-dimethoxyphenyl)-7-methyl-7,8-dihydro-6h-[1,3]dioxolo[4,5-g]chromen-6-yl]-4-methylbenzenesulfonohydrazide 383134 NSC671175 sensitive
hsa-miR-497-5p N'-chloro-4-[2-[2-[4-[(Z)-N'-chlorocarbamimidoyl]phenoxy]ethyl-(4-methylphenyl)sulfonylamino]ethoxy]benzenecarboximidamide 45028721 NSC743909 sensitive
hsa-miR-497-5p N'-decyl-4-[4-[4-(N'-decylcarbamimidoyl)phenyl]piperazin-1-yl]benzenecarboximidamide;hydrochloride 24203698 NSC729166 sensitive
hsa-miR-497-5p N-((2,3-dimethoxy-6-quinoxalinyl)methyl)-3,4,5-trimethoxy-n-(2-propynyl)aniline 394503 NSC698048 sensitive
hsa-miR-497-5p N-(1,3-benzothiazol-2-yl)-2-phenyl-7-(3,4,5-trimethoxyphenyl)pyrazolo[1,5-a]pyrimidine-5-carboxamide 71624130 NSC763635 sensitive
hsa-miR-497-5p N-(3-chloro-1,4-dioxonaphthalen-2-yl)-2-(4-hydroxy-2-oxochromen-3-yl)-2-oxoacetamide 54693275 NSC649811 sensitive
hsa-miR-497-5p N-(3-chloro-1,4-dioxonaphthalen-2-yl)-4-[2-[(3,4-dioxonaphthalen-2-yl)amino]phenyl]-2,4-dioxobutanamide 369475 NSC641245 sensitive
hsa-miR-497-5p N-(7-chloroquinolin-4-yl)-N',N'-diethyl-2-(4-methoxyphenyl)butane-1,4-diamine 223171 NSC13300 resistant
hsa-miR-497-5p N-[(22s)-13-methoxy-18-methylsulfanyl-19-oxo-4,11-diazapentacyclo[12.10.0.03,12.05,10.015,21]tetracosa-1,3,5,7,9,11,13,15,17,20-decaen-22-yl]acetamide 395872 NSC700913 sensitive
hsa-miR-497-5p N-[(e)-[4-(diethylamino)-2-hydroxyphenyl]methylideneamino]-2-[[2-(trifluoromethyl)pyridin-4-yl]amino]benzamide 135968272 NSC747458 resistant
hsa-miR-497-5p N-[(E)-1-pyrimidin-4-ylethylideneamino]-1,3-benzothiazol-2-amine 5351439 NSC693632 resistant
hsa-miR-497-5p N-[(Z)-1-(4-oxo-3,1-benzoxazin-2-yl)-2-phenylethenyl]benzamide 5917766 NSC686428 sensitive
hsa-miR-497-5p N-[2-(1h-indol-3-yl)ethyl]-4-[[[(e)-3-(4-phenylphenyl)prop-2-enoyl]amino]methyl]benzamide 5470491 NSC702137 resistant
hsa-miR-497-5p N-[2-(dimethylamino)ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide 3508054 NSC751342 resistant
hsa-miR-497-5p N-[2-(dimethylamino)ethyl]-4-(furo[3,2-c]quinolin-4-ylamino)benzamide 24204686 NSC732490 resistant
hsa-miR-497-5p N-[2-(dimethylamino)ethyl]-9-fluorophenazine-1-carboxamide;hydrochloride 386521 NSC678925 resistant
hsa-miR-497-5p N-[2-(dimethylamino)ethyl]-9-nitrodibenzo-p-dioxin-1-carboxamide;hydrochloride 370721 NSC644221 resistant
hsa-miR-497-5p N-[2-[[4,5-dihydroxy-2-methyl-6-(7H-purin-6-ylamino)oxan-3-yl]amino]-2-oxoethyl]-14-methylpentadecanamide 4366047 NSC268251 resistant
hsa-miR-497-5p N-[3-(dimethylamino)propyl]-9-oxo-2-thia-11,14-diazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(10),3,5,7,12,14,16-heptaene-13-carboxamide 385059 NSC675988 resistant
hsa-miR-497-5p N,N'-bis[(5E)-5-[(3,4-dihydroxyphenyl)methylidene]-2-(2-hydroxynaphthalen-1-yl)-4-oxo-1,3-thiazolidin-3-yl]decanediamide 5470052 NSC697192 resistant
hsa-miR-497-5p N,N-diethyl-2-[(E)-(3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ylidene)amino]oxyethanamine 6065911 NSC680094 resistant
hsa-miR-497-5p Nabor orange r 135436499 NSC4434 sensitive
hsa-miR-497-5p Naphtho[1,2-b]quinolizinium, 10,13-dimethyl- chloride 20245316 NSC78629 sensitive
hsa-miR-497-5p Naphtho[2,1-b]quinolizinium, 7-methyl- chloride 5351151 NSC28002 sensitive
hsa-miR-497-5p Ncichal_000043 393018 NSC694266 sensitive
hsa-miR-497-5p Neuro_000327 16683203 NSC643859 sensitive
hsa-miR-497-5p Neuro_000347 438571 NSC645835 resistant
hsa-miR-497-5p Nleoexcpikohjb-uhfffaoysa-n 347804 NSC406666 resistant
hsa-miR-497-5p NSC697653 NSC697653 resistant
hsa-miR-497-5p NSC724065 NSC724065 resistant
hsa-miR-497-5p NSC755523 NSC755523 resistant
hsa-miR-497-5p NSC763238 NSC763238 sensitive
hsa-miR-497-5p Octadecylphosphocholine 125219 NSC282880 resistant
hsa-miR-497-5p Octanamide, 2-amino-n-(2,5-dimethyl-1h-pyrrol-1-yl)-2-hexyl- 380384 NSC665899 sensitive
hsa-miR-497-5p Olaparib 23725625 NSC747856 approved sensitive
hsa-miR-497-5p P-fuchsin 11292 NSC10460 sensitive
hsa-miR-497-5p Pan (van) 6825 NSC5332 resistant
hsa-miR-497-5p Paullone analog 44 395169 NSC699471 sensitive
hsa-miR-497-5p Pc 287 239486 NSC44580 resistant
hsa-miR-497-5p Peliomycin (usan) NSC76455 sensitive
hsa-miR-497-5p Perifosine 148177 NSC639966 resistant
hsa-miR-497-5p Phosphonium, triphenylpropenyl-, bromide, (e)- (8ci) 10714966 NSC289922 sensitive
hsa-miR-497-5p Proflavine hcl 197873 NSC605756 resistant
hsa-miR-497-5p Pyrazolanthrone 8515 NSC75890 resistant
hsa-miR-497-5p Questiomycin a 72725 NSC94945 sensitive
hsa-miR-497-5p Replaced cas registry number(s): 66835-31-2 312122 NSC220334 sensitive
hsa-miR-497-5p Reumycin 5351216 NSC99733 resistant
hsa-miR-497-5p Sc-60646 419381 NSC114382 sensitive
hsa-miR-497-5p Sodium;3-hydroxy-4-[(1-hydroxynaphthalen-2-yl)diazenyl]-8-nitronaphthalene-1-sulfonate 135488931 NSC85561 resistant
hsa-miR-497-5p Sr16388 54612678 NSC745098 sensitive
hsa-miR-497-5p Stereoisomer of nsc 674067-p 384359 NSC674066 resistant
hsa-miR-497-5p Stk673166 NSC717468 sensitive
hsa-miR-497-5p Stl437902 228624 NSC21683 sensitive
hsa-miR-497-5p Tetrafluoro[?]one 383501 NSC671886 sensitive
hsa-miR-497-5p Tetramethyl (1r,5r,6s,9s)-7-[4-[(e)-2,3-bis(4-chlorophenyl)prop-2-enoyl]oxyphenyl]-3,5-dihydroxybicyclo[3.3.1]non-2-ene-2,4,6,9-tetracarboxylate 54681588 NSC717067 resistant
hsa-miR-497-5p Thujaplicin mixture 252101 NSC73300 resistant
hsa-miR-497-5p Tunicamycin 16727450 NSC177382 resistant
hsa-miR-497-5p Verrucarin a 9,10-epoxide 5358836 NSC283445 resistant
hsa-miR-497-5p Xnivbtjmwlisex-djkkodmxsa-n 9571538 NSC681776 sensitive
hsa-miR-497-5p Z24759926 4853660 NSC743408 sensitive
hsa-miR-497-5p Z28714792 2671841 NSC746248 sensitive
hsa-miR-497-5p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-497-5p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive Low Gastric Cancer cell line (SGC7901)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive Low Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-497-5p Vincristine 5978 approved sensitive Low Gastric Cancer cell line (SGC7901)
hsa-miR-497-5p Vincristine 5978 approved sensitive Low Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive Low Colorectal Cancer cell line (HCT-116)
hsa-miR-497-5p Fluorouracil 3385 NSC19893 approved sensitive Low Colorectal Cancer cell line (HCT-116)
hsa-miR-497-5p Trail sensitive Low Colorectal Cancer cell line (HCT-116)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive Low Epidermoid Carcinoma cell line (KB-3-1, KB-CP.5, KB-CP20)
hsa-miR-497-5p Paclitaxel 36314 NSC125973 approved sensitive High Ovarian Cancer cell line (IOSE386, IOSE397, A2780, KF, SKOV3, TOUS3,TU-OC-1, OVCAR-3, OV2008, CI3)
hsa-miR-497-5p Gemcitabine 60750 NSC613327 approved sensitive Low Pancreatic Cancer cell line (BxPC-3, AsPC-1)
hsa-miR-497-5p Temozolomide 5394 NSC362856 approved resistant Low Glioma cell line (U87, U251)
hsa-miR-497-5p Platinum-based doublet chemotherapy resistant High Lung Adenocarcinoma tissue
hsa-miR-497-5p Erlotinib 176870 NSC718781 approved sensitive Low Pancreatic Cancer cell line (MIA-PaCa-2)
hsa-miR-497-5p Gemcitabine 60750 NSC613327 approved sensitive Low Pancreatic Cancer cell line (MIA-PaCa-2, SW1990)
hsa-miR-497-5p Vincristine 5978 approved sensitive High Colorectal Cancer cell line (HCT-8)
hsa-miR-497-5p Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer cell line (HCT-116)
hsa-miR-497-5p Gefitinib 123631 NSC715055 approved resistant High Lung Adenocarcinoma cell line (A549)
hsa-miR-497-5p Fluorouracil 3385 NSC19893 approved sensitive Low Colorectal Cancer tissue and cell line (SW480, LoVo)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive Low Ovarian Cancer cell line (A2780, SKOV3)
hsa-miR-497-5p Doxorubicin 31703 NSC123127 approved sensitive Low Diffuse Large B-Cell Lymphoma cell line (RI-1, U2932, Karpas-422, SUDHL4)
hsa-miR-497-5p Doxorubicin 31703 NSC123127 approved sensitive Low Diffuse Large B-Cell Lymphoma cell line (RI-1, U2932, Karpas-422, SUDHL4)
hsa-miR-497-5p Rituximab sensitive Low Diffuse Large B-Cell Lymphoma cell line (RI-1, U2932, Karpas-422, SUDHL4)
hsa-miR-497-5p Rituximab sensitive Low Diffuse Large B-Cell Lymphoma cell line (RI-1, U2932, Karpas-422, SUDHL4)
hsa-miR-497-5p Vincristine 5978 approved sensitive Low Diffuse Large B-Cell Lymphoma cell line (RI-1, U2932, Karpas-422, SUDHL4)
hsa-miR-497-5p Vincristine 5978 approved sensitive Low Diffuse Large B-Cell Lymphoma cell line (RI-1, U2932, Karpas-422, SUDHL4)
hsa-miR-497-5p Platinum 23939 resistant High Ovarian Cancer tissue
hsa-miR-497-5p Aromatase Inhibitor sensitive Low Breast Cancer cell line (MCF-7)
hsa-miR-497-5p Temozolomide 5394 NSC362856 approved resistant Low Glioma cell line (SF295, U87)
hsa-miR-497-5p Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-497-5p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive Low Urothelial Bladder Cancer cell line (T24)
hsa-miR-497-5p Gemcitabine 60750 NSC613327 approved sensitive Low Urothelial Bladder Cancer cell line (T24)
hsa-miR-497-5p Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-497-5p Azacitidine 9444 NSC102816 approved resistant High Acute Myeloid Leukemia tissue
hsa-miR-497-5p Bortezomib 387447 NSC681239 approved sensitive Low Multiple Myeloma cell line (RPMI-8266, U-266)
hsa-miR-497-5p Radioactivity Iodine sensitive High Papillary Thyroid Cancer tissue
hsa-miR-497-5p Oxaliplatin 6857599 NSC266046 approved sensitive Low Colorectal Cancer cell line (HCT-116, RKO)
hsa-miR-497-5p Fluorouracil 3385 NSC19893 approved sensitive Low Colorectal Cancer cell line (HCT-116, RKO)
hsa-miR-497-5p Paclitaxel 36314 NSC125973 approved resistant High Ovarian Cancer cell line (W1)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive High Gastric Cancer cell line (SGC7901)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive Low Laryngeal Squamous Cell Carcinoma cell line (Hep2, TU212)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive Low Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-497-5p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-497-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-497-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM43)
hsa-miR-497-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM47)
hsa-miR-497-5p Doxorubicin 31703 NSC123127 approved sensitive cell line (HS578T)
hsa-miR-497-5p Tamoxifen 2733525 NSC180973 approved resistant cell line (LCC2)
hsa-miR-497-5p Exemestane 60198 NSC713563 approved resistant cell line (MCF-7)
hsa-miR-497-5p Testosterone 6013 NSC9700 approved resistant cell line (MCF-7)
hsa-miR-497-5p Testosterone+Anastrozole resistant cell line (MCF-7)
hsa-miR-497-5p Testosterone+Exemestane resistant cell line (MCF-7)
hsa-miR-497-5p Testosterone+Letrozole resistant cell line (MCF-7)
hsa-miR-497-5p Testosterone+Tamoxifen resistant cell line (MCF-7)
hsa-miR-497-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-497-5p Sunitinib 5329102 NSC750690 approved sensitive tissue (clear cell renal cell carcinoma)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-497-5p Ethanol+Tamoxifen sensitive cell line (LY2)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (RPMI2650)
hsa-miR-497-5p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-497-5p Pegylated interferon alpha+Ribavirin sensitive tissue (chronic hepatitis C)
hsa-miR-497-5p Platinum 23939 resistant tissue (non-small cell lung cancer)
hsa-miR-497-5p Platinum-based doublet chemotherapy resistant tissue (lung adenocarcinoma)
hsa-miR-497-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (PC3PR70)
hsa-miR-497-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (PC3PR200)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-497-5p Neoadjuvant chemotherapy resistant tissue (breast cancer)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (H460)
hsa-miR-497-5p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)
hsa-miR-497-5p Cisplatin 5460033 NSC119875 approved resistant cell line (TOV-112D)

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