miRTarBase - #MIRT061275


—
pre-miRNA Information
pre-miRNA hsa-mir-5696   
Genomic Coordinates chr2: 101309450 - 101309534
Description Homo sapiens miR-5696 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-5696
Sequence 4| CUCAUUUAAGUAGUCUGAUGCC |25
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs571745487 3 dbSNP
rs1187652258 4 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol IPO7   
Synonyms Imp7, RANBP7
Description importin 7
Transcript NM_006391   
Expression
Putative miRNA Targets on IPO7
3'UTR of IPO7
(miRNA target sites are highlighted)		 
>IPO7|NM_006391|3'UTR
   1 GTTATCTCTTTCTTTCCTGCTGTGTGCTTGTAGTGAAGAGCTTGTGTTCCTCCTAGTAGTGGTTCCAGAACTGGTTCATG
  81 TTATCTATTCTAAACTAATAATCAATAGATGGACAAAAGAAACAACAACCCCAGGAGATGGGACCTGATCATGCAACCTG
 161 GCACTGGAAAAGAAATCAGCGGGATTTTGGGGGTGGGGGGGGATGGGAGGTACCTTAGAGGGAGTATTTTCTTTATTTTT
 241 TGAAGAAAGTAAGATCCTGACTCTGAAGCTTCAAAGTGACACTGTGGAAATCTGAAACGAGGGGATGTCATGAAGGCAGC
 321 TTTTCTTTTTCTGAGGAAAAAATAGGCATGGGCTACAGGACTATTTAAAATGTCTCATTTACAGTATAAAACTCAAAGGT
 401 AGATGTAATTTTTACACCTATGAGTATTTGTCCAATTTCTGTCTCTTCCTCACCATTGGGTATCTATTCTTTATATGTAA
 481 ATAAGATAAGGTCATCTGATAGCCTTATTCAGTCTTCATCATTTTCATCATTGTTCCTATGTAGATTATTGGACATTTAT
 561 TGTAGCACTACATAACTGATTATAAAAATCTGTAAATGAATTAGCACTTTCATATTGAAACAAGCCTGCTAGCCTATGTA
 641 TAAAATAGCAAAATGTTTGCTGTTTATAAAAAGATGTAATGGGGTGGGGGGCAGGGGTAATTTCAAGTTATTAATTTAAA
 721 AATGAACTAGCAATTTTGTACCTGGTGACTTTGTGGTGCACTCACCTCTGATAGTGACTTGAATTCGGTATGTAAAAAGG
 801 GGTTAGTGGTATTTCATTGCTGCTAAAAATGACAACTCCCTCTGTGTCCTGTTTTTCTTAAAGCTGTCAGTGTACAAGTG
 881 GGTATTTGAATACCAGACCTTACTGTAAAAAATAAAAAAGGTGGTATCTAGAGCATGTAAATTGGATATAAAGTTCTGCT
 961 CTTAAAGAGTTGATCTAAGAGTATGGCTAAACATCTATATATGCAATCTATTAAAAGAACTTAATTCGGCTATTATGTCT
1041 TGATTTGATTGCAGTTTTTTCCTAATTATAACAAATTTTTCCTCATTGGCCTGTTTTTAATCCTGTGCCTAGAAGGAGTA
1121 CAAAATGCACACTTTACAAAATTGATATTTAACACTTACCCACTCCCCTTTCCCCATCTCTTCTACCGCTCTTGTTGATC
1201 GTGGTATCTGATCTTGACTAGATAGGCTGAAGGCACATGGTTCCCTCCAAAAACCACTATTGATACCACTACAAAAACAA
1281 GCCAGCAAAAAGATACTGTAGAGAGGTTGGCTTGCTTCCCTCTCTTCCTAACTGCATGTTGAAAAATAAGCCGTTATTGA
1361 TCTTAAACATCGGTCAGATGAGTCATACATTGGGTTATTTTTTATATACATGTATACACAAAATATTTCAAATTGAAAGC
1441 AACATCTTAATGGATTCAAAACTATTACAAGCTGTTGTCTAAAACAGGTGAGAAAAAAATTTATAACTGTAAAAACAAAT
1521 GCACATATTGATATTTAAAATGCGTAATTAAGAAAACCCATTGTTGTTGTGTTTTTCTTGTATACCAATAATTAAGCCAC
1601 TACTGTTGGCACTGTTTGGTTTTCTATTTTAACACTGAAGGAGTGAAAGTATTTCCTATATTTATGAATTTACTACTAAA
1681 ATCTTGGCAAAAAAAGAAAAAAATTGTCTAACGTGTGTGGGTGAAAACTGTTAATCAAGTGTTTCTACTCCCCCCCGAAA
1761 ATCCCCTGAAAGTTGGACACCAACTGTATACCCTAGGTTGCTTAAAGGGATTTCACTATTATATAAAGTCAATAAAAATG
1841 AAGTAGTTGTATATATGCAACATTGTGTACAGAGGGGAAATAATGAATAGTATTAAAGAAACATTCTCGTCTTCCTTTAC
1921 CTTTAATCCCCTAATACCTAGTCTACTTTTTAAATTTTCAGACTTCACTGCTTTTTGAATTCATAATTCTAATTTTCACA
2001 TTATTGTTAATGGAAAATCATATCTAATAAAGGTTTTAGTTATTCCCATGCACAGTATGAAAATTCTCATTTGCTGAGGT
2081 TTTGTTTCAAGAAAATGTATTGGCATGTCTTTGAGAACATGTTTTATTGTCTCCTGTGTCATATAATCCAAACTAATCTC
2161 CGTTTACAGACTTTAACTTGAAATTAGACCTTATAATTAAACTATTTAAATAGTGTTCAAATGATAGTTTCTAATGCATC
2241 AAATATATACCTCAGTTTTCATGATTTCCTTTAACATTATAATTTGGTATAGATCAAGAATCTTAACATGTATCAGTTTC
2321 TAGATGAGGCTGCAGGATTTTTGGAAAACTTTTTGAATGTATTTACAATATTCTCTTGTAATTAGCTACATAGGGACTTG
2401 TCTTTTTTTCTTTTTACATACAGCTTTTCCTACAGTTTTATTACCCTGTAATTTTTTTTTAGTTGTAGAAGTTAATTCTG
2481 ATTTTGTGTGGATTTCAGTATTTGTCTTTGTTAATGGCACATATTAGCATAAATCACTTTTGTAAATGTAAGCTTTCTTT
2561 TTTTTTCTTGAAAAAGCCTTTCTATTTATCAGTATTAAATAAAGGAAGTTAATCTGTTTCTCTGCAGGTAATAAAATAGT
2641 GACACACTGTATTAAGATAGTGACTGCTATACTCAACTCTGGAAGAGACTAGAGTATAGAGCATGAGTGGCAAAACCACA
2721 GCCCTTGGGCCATATGCTGCTATTCAGTCCCAGATGTAGCCCCTGAAGCAAGCATAAAGAAAAATGAATTAAAAATTAAA
2801 TTAATATGGAAAGTTAAAAAATGGATTACATTAGTATGACTAAACCATGTCTTTGGCAAAGATCTAACACAATGTCTTAA
2881 GTATAATAGGTAGTCTCTGTTTGTAAAATAAATGACTTAAATTTAAAACATCAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ccGUAGUCUGAUGAAUUUACUc 5'
            :||||| :| | ||:|||| 
Target 5' tgTATCAG-TTTC-TAGATGAg 3'
 2309 - 2328 142.00 -15.70
2 
miRNA  3' ccgUAGUCUGAUGAAUUUAcuc 5'
             ||:| ||||:||||||   
Target 5' ataATTAAACTATTTAAATagt 3'
 2193 - 2214 139.00 -10.30
3 
miRNA  3' ccGUAGUC-UGAUGAAUUUACUc 5'
            :||||| |:||  |||| || 
Target 5' ttTATCAGTATTAAATAAAGGAa 3'
 2585 - 2607 136.00 -7.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN19726807 8 COSMIC
COSN30179036 69 COSMIC
COSN31536574 81 COSMIC
COSN30519155 109 COSMIC
COSN20433745 148 COSMIC
COSN26646599 177 COSMIC
COSN31875113 195 COSMIC
COSN20107957 203 COSMIC
COSN24360922 694 COSMIC
COSN7293104 811 COSMIC
COSN5924981 949 COSMIC
COSN32062471 1784 COSMIC
COSN15728836 1875 COSMIC
COSN6534323 1921 COSMIC
COSN1140009 2290 COSMIC
COSN20709434 2743 COSMIC
COSN21985355 2839 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1200771965 2 dbSNP
rs1265844773 3 dbSNP
rs1251146950 5 dbSNP
rs1218287799 6 dbSNP
rs764351839 7 dbSNP
rs761975581 9 dbSNP
rs765856307 12 dbSNP
rs1216524477 13 dbSNP
rs750894148 14 dbSNP
rs1468109708 19 dbSNP
rs1179393743 23 dbSNP
rs758721486 25 dbSNP
rs780419152 26 dbSNP
rs371155574 28 dbSNP
rs1416759188 30 dbSNP
rs1357498137 31 dbSNP
rs1333513661 45 dbSNP
rs1410757808 47 dbSNP
rs535881443 63 dbSNP
rs1169039381 74 dbSNP
rs1415543418 78 dbSNP
rs910158905 79 dbSNP
rs948293016 86 dbSNP
rs757274908 88 dbSNP
rs11042357 96 dbSNP
rs11042358 98 dbSNP
rs1436839039 99 dbSNP
rs1259551266 100 dbSNP
rs1196576475 106 dbSNP
rs1317053789 110 dbSNP
rs1293899725 121 dbSNP
rs1235066086 123 dbSNP
rs1320750945 130 dbSNP
rs1330125397 134 dbSNP
rs866739307 136 dbSNP
rs61876790 141 dbSNP
rs1433726618 151 dbSNP
rs1276101480 155 dbSNP
rs1337807794 156 dbSNP
rs183668627 157 dbSNP
rs1465495068 160 dbSNP
rs1395682616 168 dbSNP
rs1167481549 171 dbSNP
rs1227647181 181 dbSNP
rs371660574 182 dbSNP
rs938449014 183 dbSNP
rs1330903596 185 dbSNP
rs1210849561 189 dbSNP
rs1056870804 194 dbSNP
rs1319886345 194 dbSNP
rs1289036485 195 dbSNP
rs1307092081 195 dbSNP
rs398015313 195 dbSNP
rs60115807 195 dbSNP
rs891546351 195 dbSNP
rs3217640 196 dbSNP
rs945884189 197 dbSNP
rs1042896242 198 dbSNP
rs1196933571 200 dbSNP
rs1400847612 202 dbSNP
rs1156241949 203 dbSNP
rs1248514161 205 dbSNP
rs1253196212 210 dbSNP
rs1478652029 217 dbSNP
rs1182008990 223 dbSNP
rs1192744276 237 dbSNP
rs904450510 252 dbSNP
rs754085078 264 dbSNP
rs1459199038 265 dbSNP
rs1489199770 283 dbSNP
rs753635746 284 dbSNP
rs539072383 294 dbSNP
rs369428057 299 dbSNP
rs1239471384 302 dbSNP
rs1348923925 303 dbSNP
rs1018276880 308 dbSNP
rs901134620 309 dbSNP
rs559009096 325 dbSNP
rs572446132 326 dbSNP
rs1160322004 334 dbSNP
rs533846194 349 dbSNP
rs1289745047 353 dbSNP
rs1403227545 356 dbSNP
rs1324964831 361 dbSNP
rs553992229 362 dbSNP
rs1359131781 371 dbSNP
rs998133804 384 dbSNP
rs1025723113 387 dbSNP
rs1395367985 389 dbSNP
rs1177789239 410 dbSNP
rs1431027202 417 dbSNP
rs1424222383 421 dbSNP
rs951449443 422 dbSNP
rs1489250633 423 dbSNP
rs573791351 439 dbSNP
rs778885929 442 dbSNP
rs1352234663 450 dbSNP
rs1228826061 454 dbSNP
rs542801590 456 dbSNP
rs981393924 457 dbSNP
rs1296769374 460 dbSNP
rs926989779 463 dbSNP
rs1264637422 465 dbSNP
rs938383256 487 dbSNP
rs1398923965 492 dbSNP
rs1375528517 499 dbSNP
rs1304021189 503 dbSNP
rs992474049 505 dbSNP
rs913013095 531 dbSNP
rs1355985823 538 dbSNP
rs945748345 540 dbSNP
rs1042928211 548 dbSNP
rs904314988 553 dbSNP
rs1208227760 554 dbSNP
rs942640354 560 dbSNP
rs748219204 563 dbSNP
rs149600432 573 dbSNP
rs1490523158 575 dbSNP
rs1200970188 576 dbSNP
rs901088195 582 dbSNP
rs1257752915 588 dbSNP
rs1234455190 613 dbSNP
rs1342734949 626 dbSNP
rs1314291381 635 dbSNP
rs1393762312 636 dbSNP
rs998164669 637 dbSNP
rs1331598589 652 dbSNP
rs1467047688 656 dbSNP
rs1397850407 661 dbSNP
rs1169619373 662 dbSNP
rs1461910893 663 dbSNP
rs1370077172 664 dbSNP
rs1185564018 668 dbSNP
rs1025587274 674 dbSNP
rs1204495724 674 dbSNP
rs1250295959 681 dbSNP
rs1251585243 685 dbSNP
rs1473855360 686 dbSNP
rs887206965 687 dbSNP
rs373742051 689 dbSNP
rs1368196250 693 dbSNP
rs1471606432 694 dbSNP
rs1005571017 696 dbSNP
rs373327209 697 dbSNP
rs1264183581 701 dbSNP
rs1164598171 715 dbSNP
rs1017107649 734 dbSNP
rs1428604774 751 dbSNP
rs1305613603 752 dbSNP
rs969928936 753 dbSNP
rs369916744 759 dbSNP
rs770778971 764 dbSNP
rs1374132591 766 dbSNP
rs1330463069 772 dbSNP
rs1387104236 773 dbSNP
rs1002370473 781 dbSNP
rs1311760191 782 dbSNP
rs1035702081 787 dbSNP
rs1457286630 787 dbSNP
rs538526617 788 dbSNP
rs758596796 794 dbSNP
rs1286223419 798 dbSNP
rs1177566137 799 dbSNP
rs1438100443 800 dbSNP
rs1379887660 816 dbSNP
rs992505370 817 dbSNP
rs1453674622 826 dbSNP
rs745722237 830 dbSNP
rs778077503 836 dbSNP
rs144275708 839 dbSNP
rs967121074 840 dbSNP
rs1484328286 866 dbSNP
rs1196815791 867 dbSNP
rs775170590 873 dbSNP
rs978472128 878 dbSNP
rs1332601459 882 dbSNP
rs1321274310 899 dbSNP
rs189553736 900 dbSNP
rs925718181 903 dbSNP
rs1440998503 913 dbSNP
rs1417918872 915 dbSNP
rs192445437 921 dbSNP
rs1385524924 924 dbSNP
rs561623258 934 dbSNP
rs1448500324 936 dbSNP
rs942567270 937 dbSNP
rs1429657504 939 dbSNP
rs1039521025 947 dbSNP
rs1218225130 949 dbSNP
rs1249604072 950 dbSNP
rs184831886 957 dbSNP
rs1391417453 965 dbSNP
rs1462438926 970 dbSNP
rs922540359 972 dbSNP
rs1200691016 979 dbSNP
rs1346623827 982 dbSNP
rs1272891344 993 dbSNP
rs1302155521 998 dbSNP
rs933882705 1007 dbSNP
rs1047069600 1011 dbSNP
rs1280005075 1013 dbSNP
rs1398307412 1013 dbSNP
rs887071489 1020 dbSNP
rs1334845581 1021 dbSNP
rs542927430 1022 dbSNP
rs1334558588 1028 dbSNP
rs1172396802 1033 dbSNP
rs757418393 1036 dbSNP
rs1426481176 1040 dbSNP
rs1038896944 1053 dbSNP
rs879117301 1054 dbSNP
rs1295496233 1055 dbSNP
rs1187590606 1057 dbSNP
rs1344353145 1057 dbSNP
rs1443829292 1067 dbSNP
rs1228817252 1075 dbSNP
rs550385178 1076 dbSNP
rs905255043 1083 dbSNP
rs1318336035 1087 dbSNP
rs1259679809 1091 dbSNP
rs1216732862 1094 dbSNP
rs1339695286 1099 dbSNP
rs1002811596 1101 dbSNP
rs1450255847 1104 dbSNP
rs1035163671 1111 dbSNP
rs960964139 1116 dbSNP
rs1466530660 1122 dbSNP
rs570231300 1124 dbSNP
rs1343457895 1128 dbSNP
rs1465591269 1131 dbSNP
rs1415121497 1132 dbSNP
rs148726795 1136 dbSNP
rs1235449081 1145 dbSNP
rs1202624576 1154 dbSNP
rs1009781856 1158 dbSNP
rs1019968527 1158 dbSNP
rs1196479447 1159 dbSNP
rs373860169 1162 dbSNP
rs1290474506 1163 dbSNP
rs967068840 1167 dbSNP
rs978448307 1169 dbSNP
rs925717573 1170 dbSNP
rs1249383087 1173 dbSNP
rs76664366 1176 dbSNP
rs1174706986 1177 dbSNP
rs975666887 1184 dbSNP
rs1375923481 1186 dbSNP
rs558368922 1188 dbSNP
rs1351035102 1189 dbSNP
rs1326106829 1193 dbSNP
rs189764583 1195 dbSNP
rs773734012 1198 dbSNP
rs761326687 1200 dbSNP
rs908452002 1201 dbSNP
rs1381743778 1202 dbSNP
rs1387544715 1204 dbSNP
rs1480178629 1222 dbSNP
rs1223681545 1225 dbSNP
rs1449738145 1227 dbSNP
rs1291172716 1234 dbSNP
rs941386347 1246 dbSNP
rs746438175 1247 dbSNP
rs1307333695 1249 dbSNP
rs1318725997 1254 dbSNP
rs1239965960 1257 dbSNP
rs1367590996 1261 dbSNP
rs1368758568 1266 dbSNP
rs905285210 1272 dbSNP
rs1002255809 1273 dbSNP
rs1349766950 1278 dbSNP
rs1057054713 1279 dbSNP
rs896628929 1280 dbSNP
rs1300678188 1293 dbSNP
rs1156452262 1296 dbSNP
rs1311020985 1297 dbSNP
rs1425624912 1299 dbSNP
rs1236000650 1301 dbSNP
rs1192660644 1302 dbSNP
rs1009726226 1305 dbSNP
rs1328864952 1315 dbSNP
rs1268068933 1322 dbSNP
rs1429561804 1323 dbSNP
rs1206463349 1324 dbSNP
rs750938780 1334 dbSNP
rs571904441 1337 dbSNP
rs1173710658 1344 dbSNP
rs904102075 1353 dbSNP
rs553826150 1354 dbSNP
rs142280670 1358 dbSNP
rs370505639 1370 dbSNP
rs866169885 1373 dbSNP
rs1345486804 1377 dbSNP
rs1032644466 1380 dbSNP
rs964135868 1390 dbSNP
rs536091947 1393 dbSNP
rs1295745351 1398 dbSNP
rs1434841810 1398 dbSNP
rs181543508 1400 dbSNP
rs1410981984 1405 dbSNP
rs1178028544 1407 dbSNP
rs575803071 1411 dbSNP
rs185872782 1415 dbSNP
rs755283944 1416 dbSNP
rs982559392 1418 dbSNP
rs1161064254 1427 dbSNP
rs556452036 1430 dbSNP
rs1347244551 1433 dbSNP
rs553857317 1438 dbSNP
rs147869424 1441 dbSNP
rs1257954366 1443 dbSNP
rs1208532325 1451 dbSNP
rs1323266522 1454 dbSNP
rs189157722 1459 dbSNP
rs752734790 1461 dbSNP
rs181912047 1473 dbSNP
rs1056592096 1476 dbSNP
rs896555270 1478 dbSNP
rs1379518328 1487 dbSNP
rs1304222263 1493 dbSNP
rs746346546 1493 dbSNP
rs945567207 1499 dbSNP
rs1042571102 1501 dbSNP
rs1467152776 1508 dbSNP
rs904113193 1514 dbSNP
rs1421357245 1516 dbSNP
rs1169885360 1528 dbSNP
rs879528420 1532 dbSNP
rs1258609929 1544 dbSNP
rs1001084145 1545 dbSNP
rs757179460 1557 dbSNP
rs1033109115 1561 dbSNP
rs1227012505 1570 dbSNP
rs899467604 1572 dbSNP
rs1290584546 1573 dbSNP
rs1317155689 1576 dbSNP
rs14432 1578 dbSNP
rs14433 1581 dbSNP
rs1251232493 1587 dbSNP
rs1220285815 1589 dbSNP
rs1321799687 1590 dbSNP
rs541000642 1596 dbSNP
rs1263198364 1598 dbSNP
rs1331841785 1603 dbSNP
rs996901309 1606 dbSNP
rs1029389091 1608 dbSNP
rs1297529962 1610 dbSNP
rs1489145250 1611 dbSNP
rs955120782 1619 dbSNP
rs561462256 1626 dbSNP
rs4810 1627 dbSNP
rs562878776 1635 dbSNP
rs1381118189 1636 dbSNP
rs1180962480 1644 dbSNP
rs550469940 1647 dbSNP
rs745843677 1649 dbSNP
rs781029993 1652 dbSNP
rs1210975231 1658 dbSNP
rs1489727155 1659 dbSNP
rs1266735119 1660 dbSNP
rs1219587234 1678 dbSNP
rs1043220 1697 dbSNP
rs1358352748 1702 dbSNP
rs1408375691 1704 dbSNP
rs973989824 1707 dbSNP
rs531947178 1713 dbSNP
rs938050780 1713 dbSNP
rs8785 1714 dbSNP
rs552743938 1718 dbSNP
rs1387301307 1724 dbSNP
rs1392741459 1729 dbSNP
rs918040581 1733 dbSNP
rs945408613 1734 dbSNP
rs1164297817 1738 dbSNP
rs1042581411 1739 dbSNP
rs566158473 1744 dbSNP
rs185841428 1746 dbSNP
rs936931852 1748 dbSNP
rs1039315601 1750 dbSNP
rs1435470002 1750 dbSNP
rs900731008 1750 dbSNP
rs1265863846 1751 dbSNP
rs1219685077 1755 dbSNP
rs996562232 1758 dbSNP
rs1050687491 1763 dbSNP
rs1286019734 1776 dbSNP
rs564789000 1777 dbSNP
rs1348036531 1779 dbSNP
rs1259956893 1784 dbSNP
rs890881244 1793 dbSNP
rs1332809062 1797 dbSNP
rs1003896343 1798 dbSNP
rs1404189346 1805 dbSNP
rs1015395462 1810 dbSNP
rs962604082 1815 dbSNP
rs565526406 1818 dbSNP
rs1384492632 1820 dbSNP
rs1173582000 1821 dbSNP
rs1408474815 1823 dbSNP
rs995730079 1832 dbSNP
rs1374459962 1846 dbSNP
rs879094514 1848 dbSNP
rs1478400378 1851 dbSNP
rs959543617 1852 dbSNP
rs1310196662 1856 dbSNP
rs992168028 1862 dbSNP
rs917884331 1866 dbSNP
rs190938370 1868 dbSNP
rs373048728 1878 dbSNP
rs1260581831 1882 dbSNP
rs1200891311 1893 dbSNP
rs978141460 1896 dbSNP
rs79372327 1899 dbSNP
rs925344625 1899 dbSNP
rs1318456078 1902 dbSNP
rs1280216254 1904 dbSNP
rs568328270 1909 dbSNP
rs527892201 1910 dbSNP
rs1039607111 1914 dbSNP
rs1482042294 1928 dbSNP
rs922239980 1943 dbSNP
rs933538301 1946 dbSNP
rs1050738997 1954 dbSNP
rs1426373083 1957 dbSNP
rs1169194794 1962 dbSNP
rs1179880576 1966 dbSNP
rs890764523 1972 dbSNP
rs1411949394 1984 dbSNP
rs1446653783 1986 dbSNP
rs1003822693 1991 dbSNP
rs548793329 1993 dbSNP
rs547971882 1998 dbSNP
rs1036807354 1999 dbSNP
rs1462337760 2000 dbSNP
rs1428416826 2007 dbSNP
rs536569193 2010 dbSNP
rs779855041 2020 dbSNP
rs555991690 2021 dbSNP
rs1212947338 2040 dbSNP
rs569557283 2046 dbSNP
rs1338835080 2047 dbSNP
rs1284799276 2052 dbSNP
rs959321658 2058 dbSNP
rs749012609 2067 dbSNP
rs906260208 2076 dbSNP
rs1447809423 2079 dbSNP
rs1336532487 2080 dbSNP
rs538445238 2085 dbSNP
rs768203577 2091 dbSNP
rs1403159003 2095 dbSNP
rs1327442405 2097 dbSNP
rs966728404 2098 dbSNP
rs558258940 2100 dbSNP
rs774038081 2104 dbSNP
rs1055187755 2105 dbSNP
rs978067735 2108 dbSNP
rs1163290151 2114 dbSNP
rs895437296 2119 dbSNP
rs1384620531 2120 dbSNP
rs1295662946 2121 dbSNP
rs572091741 2131 dbSNP
rs865919162 2132 dbSNP
rs1440066548 2135 dbSNP
rs1005756012 2142 dbSNP
rs540737441 2145 dbSNP
rs1234333015 2148 dbSNP
rs1202377770 2156 dbSNP
rs554574881 2162 dbSNP
rs574308206 2163 dbSNP
rs1211685720 2168 dbSNP
rs1357624874 2178 dbSNP
rs1221744003 2180 dbSNP
rs867839329 2188 dbSNP
rs544135186 2195 dbSNP
rs563959922 2196 dbSNP
rs527379776 2197 dbSNP
rs1030177791 2200 dbSNP
rs532800512 2206 dbSNP
rs958353521 2212 dbSNP
rs1425986175 2215 dbSNP
rs974944191 2215 dbSNP
rs1363398720 2216 dbSNP
rs955444536 2222 dbSNP
rs1439869160 2240 dbSNP
rs1409922375 2244 dbSNP
rs1175229064 2249 dbSNP
rs922072603 2250 dbSNP
rs987309483 2259 dbSNP
rs1247193780 2277 dbSNP
rs761294342 2280 dbSNP
rs1207842638 2288 dbSNP
rs1238927350 2304 dbSNP
rs1462826266 2305 dbSNP
rs964660166 2308 dbSNP
rs989375700 2313 dbSNP
rs1223552336 2321 dbSNP
rs1247512373 2322 dbSNP
rs987713382 2326 dbSNP
rs1447786530 2339 dbSNP
rs1403563131 2350 dbSNP
rs1169692132 2356 dbSNP
rs546395088 2358 dbSNP
rs1420931281 2360 dbSNP
rs915135850 2369 dbSNP
rs1419967616 2373 dbSNP
rs1003974074 2376 dbSNP
rs1174419599 2379 dbSNP
rs1037097625 2382 dbSNP
rs1042018015 2389 dbSNP
rs927713317 2391 dbSNP
rs1178506015 2392 dbSNP
rs939097840 2393 dbSNP
rs1479387500 2396 dbSNP
rs1055260625 2397 dbSNP
rs1470023506 2402 dbSNP
rs1194438813 2403 dbSNP
rs1319419107 2411 dbSNP
rs895299972 2419 dbSNP
rs1005787098 2422 dbSNP
rs771583053 2430 dbSNP
rs1432337594 2433 dbSNP
rs559625011 2436 dbSNP
rs1313151647 2445 dbSNP
rs1265319598 2446 dbSNP
rs1013410184 2452 dbSNP
rs1323407216 2452 dbSNP
rs572225154 2452 dbSNP
rs1382279145 2453 dbSNP
rs1366832589 2457 dbSNP
rs1286752352 2461 dbSNP
rs1217336810 2466 dbSNP
rs1264801279 2468 dbSNP
rs1039040345 2470 dbSNP
rs182707959 2472 dbSNP
rs999558717 2484 dbSNP
rs1428486572 2491 dbSNP
rs897380477 2492 dbSNP
rs773993800 2507 dbSNP
rs1186156045 2519 dbSNP
rs1029628795 2523 dbSNP
rs975206472 2538 dbSNP
rs1245393931 2541 dbSNP
rs1029066651 2550 dbSNP
rs1275288278 2552 dbSNP
rs954900214 2554 dbSNP
rs1259253551 2555 dbSNP
rs1308754157 2558 dbSNP
rs200756964 2558 dbSNP
rs77664782 2560 dbSNP
rs1477991641 2568 dbSNP
rs761290966 2569 dbSNP
rs1431933358 2570 dbSNP
rs1450165890 2571 dbSNP
rs1470537671 2571 dbSNP
rs940912062 2572 dbSNP
rs1331957240 2577 dbSNP
rs1386087971 2578 dbSNP
rs1352856157 2579 dbSNP
rs1017470270 2583 dbSNP
rs1424660580 2584 dbSNP
rs919561933 2585 dbSNP
rs964555720 2586 dbSNP
rs1318408279 2593 dbSNP
rs1348749985 2597 dbSNP
rs989292107 2598 dbSNP
rs1198093736 2601 dbSNP
rs1434237143 2614 dbSNP
rs1249154595 2626 dbSNP
rs1285163829 2628 dbSNP
rs766957196 2630 dbSNP
rs1022638217 2638 dbSNP
rs1055309808 2654 dbSNP
rs894877455 2662 dbSNP
rs1243234175 2664 dbSNP
rs1381779502 2670 dbSNP
rs1307378537 2673 dbSNP
rs568445360 2674 dbSNP
rs1371057516 2690 dbSNP
rs540764877 2691 dbSNP
rs777140692 2694 dbSNP
rs1348823594 2697 dbSNP
rs1207052139 2700 dbSNP
rs1046253965 2703 dbSNP
rs1161911364 2704 dbSNP
rs1285085004 2707 dbSNP
rs1424191501 2709 dbSNP
rs1381342887 2712 dbSNP
rs978196744 2719 dbSNP
rs1451061053 2720 dbSNP
rs186540683 2725 dbSNP
rs939127601 2730 dbSNP
rs990517836 2733 dbSNP
rs1481049397 2742 dbSNP
rs549712149 2743 dbSNP
rs569594250 2745 dbSNP
rs893829219 2750 dbSNP
rs538481441 2755 dbSNP
rs1410127675 2773 dbSNP
rs996176242 2783 dbSNP
rs1240896179 2786 dbSNP
rs1470974827 2794 dbSNP
rs558734961 2796 dbSNP
rs1306201950 2797 dbSNP
rs941549695 2800 dbSNP
rs565710779 2804 dbSNP
rs1405412094 2811 dbSNP
rs1347485414 2815 dbSNP
rs539728795 2816 dbSNP
rs767069462 2816 dbSNP
rs560295491 2825 dbSNP
rs1038496522 2832 dbSNP
rs1385917548 2834 dbSNP
rs954786722 2837 dbSNP
rs1452073690 2839 dbSNP
rs534722375 2861 dbSNP
rs1363513829 2864 dbSNP
rs769438526 2867 dbSNP
rs1481674871 2873 dbSNP
rs139773383 2875 dbSNP
rs930233481 2878 dbSNP
rs1196615119 2882 dbSNP
rs1490099656 2884 dbSNP
rs1261982055 2885 dbSNP
rs1015007599 2887 dbSNP
rs962288235 2888 dbSNP
rs145276820 2890 dbSNP
rs1224072313 2891 dbSNP
rs541647153 2898 dbSNP
rs891110870 2899 dbSNP
rs1366176307 2910 dbSNP
rs1222967829 2913 dbSNP
rs920842514 2917 dbSNP
rs1320537684 2923 dbSNP
rs1305961112 2929 dbSNP
rs1380684271 2933 dbSNP
rs1384725064 2934 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions LCL35
Disease MIMAT0022489
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1020022. RNA binding protein: AGO2. Condition:EBV B95-8-infected ...

- Skalsky RL; Corcoran DL; Gottwein E; Frank et al., 2012, PLoS pathogens.

Article - Skalsky RL; Corcoran DL; Gottwein E; Frank et al.
- PLoS pathogens, 2012
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role in viral oncogenesis. To date, only a limited number of EBV miRNA targets have been identified; thus, the role of EBV miRNAs in viral pathogenesis and/or lymphomagenesis is not well defined. Here, we used photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) combined with deep sequencing and computational analysis to comprehensively examine the viral and cellular miRNA targetome in EBV strain B95-8-infected lymphoblastoid cell lines (LCLs). We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs. 24 PAR-CLIP-identified miRNA:3'UTR interactions were confirmed by reporter assays. Our results reveal that EBV miRNAs predominantly target cellular transcripts during latent infection, thereby manipulating the host environment. Furthermore, targets of EBV miRNAs are involved in multiple cellular processes that are directly relevant to viral infection, including innate immunity, cell survival, and cell proliferation. Finally, we present evidence that myc-regulated host miRNAs from the miR-17/92 cluster can regulate latent viral gene expression. This comprehensive survey of the miRNA targetome in EBV-infected B cells represents a key step towards defining the functions of EBV-encoded miRNAs, and potentially, identifying novel therapeutic targets for EBV-associated malignancies.
LinkOut: [PMID: 22291592]
CLIP-seq Support 1 for dataset GSM1020022
Method / RBP PAR-CLIP / AGO2
Cell line / Condition LCL35 / EBV B95-8-infected, 4-thiouridine, RNase T1
Location of target site ENST00000379719.3 | 3UTR | UCAAGUUAUUAAUUUAAAAAUGAACUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22291592 / GSE41437
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
145 hsa-miR-5696 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT057820 SLC30A7 solute carrier family 30 member 7 2 2
MIRT061215 MED17 mediator complex subunit 17 2 2
MIRT061275 IPO7 importin 7 2 2
MIRT087540 YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta 2 2
MIRT090979 DPH3 diphthamide biosynthesis 3 2 2
MIRT100413 HSPA1B heat shock protein family A (Hsp70) member 1B 2 2
MIRT108737 XIAP X-linked inhibitor of apoptosis 2 2
MIRT116191 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 4
MIRT185488 LBR lamin B receptor 2 2
MIRT239133 GLO1 glyoxalase I 2 2
MIRT314678 TMEM167A transmembrane protein 167A 2 4
MIRT365830 ZBTB33 zinc finger and BTB domain containing 33 2 2
MIRT375653 VPS53 VPS53, GARP complex subunit 2 2
MIRT441652 DEK DEK proto-oncogene 2 2
MIRT442230 BTD biotinidase 2 2
MIRT443351 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT444349 KIAA1211 KIAA1211 2 2
MIRT444907 KIAA1841 KIAA1841 2 2
MIRT445301 PRR26 proline rich 26 2 2
MIRT446678 SMIM10 small integral membrane protein 10 2 2
MIRT449658 PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 2 4
MIRT456346 OLIG3 oligodendrocyte transcription factor 3 2 8
MIRT466384 TGOLN2 trans-golgi network protein 2 2 4
MIRT467279 SPNS1 sphingolipid transporter 1 (putative) 2 2
MIRT478065 DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 2 2
MIRT479422 CDKN1B cyclin dependent kinase inhibitor 1B 2 2
MIRT482866 SMIM12 small integral membrane protein 12 2 4
MIRT484696 RNF11 ring finger protein 11 2 2
MIRT497699 ARL6IP6 ADP ribosylation factor like GTPase 6 interacting protein 6 2 2
MIRT499111 SNRPB2 small nuclear ribonucleoprotein polypeptide B2 2 8
MIRT500787 TLK1 tousled like kinase 1 2 6
MIRT504644 RPL9 ribosomal protein L9 2 6
MIRT505947 RAN RAN, member RAS oncogene family 2 6
MIRT513837 KCTD15 potassium channel tetramerization domain containing 15 2 4
MIRT514437 C15orf59 chromosome 15 open reading frame 59 2 2
MIRT518810 AKAP8 A-kinase anchoring protein 8 2 4
MIRT519802 ZMYM2 zinc finger MYM-type containing 2 2 4
MIRT525377 SYNM synemin 2 2
MIRT525993 MAGEL2 MAGE family member L2 2 2
MIRT527715 SSC5D scavenger receptor cysteine rich family member with 5 domains 2 4
MIRT528057 OLAH oleoyl-ACP hydrolase 2 2
MIRT528636 SENP6 SUMO1/sentrin specific peptidase 6 2 2
MIRT529170 CCDC25 coiled-coil domain containing 25 2 2
MIRT529585 TMEM220 transmembrane protein 220 2 2
MIRT529806 TMLHE trimethyllysine hydroxylase, epsilon 2 2
MIRT531260 PPIL3 peptidylprolyl isomerase like 3 2 2
MIRT531428 MPZL3 myelin protein zero like 3 2 2
MIRT532139 ZNF331 zinc finger protein 331 2 2
MIRT532350 PLEK pleckstrin 2 2
MIRT533533 TPR translocated promoter region, nuclear basket protein 2 2
MIRT535822 MTFR1L mitochondrial fission regulator 1 like 2 2
MIRT539243 ANKRD50 ankyrin repeat domain 50 2 2
MIRT543556 RPF2 ribosome production factor 2 homolog 2 4
MIRT544899 DCTPP1 dCTP pyrophosphatase 1 2 2
MIRT545103 RAG1 recombination activating 1 2 2
MIRT549060 CALM1 calmodulin 1 2 2
MIRT550044 RSRC1 arginine and serine rich coiled-coil 1 2 2
MIRT550055 MDM2 MDM2 proto-oncogene 2 2
MIRT550475 TMEM241 transmembrane protein 241 2 2
MIRT550654 ZFP37 ZFP37 zinc finger protein 2 2
MIRT553599 TM7SF3 transmembrane 7 superfamily member 3 2 2
MIRT554614 RPS6KA3 ribosomal protein S6 kinase A3 2 2
MIRT555639 PHIP pleckstrin homology domain interacting protein 2 2
MIRT556262 MAPK6 mitogen-activated protein kinase 6 2 2
MIRT558529 CSRNP3 cysteine and serine rich nuclear protein 3 2 2
MIRT559171 BRAP BRCA1 associated protein 2 2
MIRT565206 TROVE2 TROVE domain family member 2 2 2
MIRT566063 RCC2 regulator of chromosome condensation 2 2 2
MIRT566721 MSL2 MSL complex subunit 2 2 2
MIRT566775 KIAA1804 mitogen-activated protein kinase kinase kinase 21 2 2
MIRT567594 FANCF Fanconi anemia complementation group F 2 2
MIRT568752 DDAH1 dimethylarginine dimethylaminohydrolase 1 2 2
MIRT571253 ALG10B ALG10B, alpha-1,2-glucosyltransferase 2 2
MIRT573768 PRKAG1 protein kinase AMP-activated non-catalytic subunit gamma 1 2 2
MIRT609525 AZI2 5-azacytidine induced 2 2 4
MIRT613118 EID1 EP300 interacting inhibitor of differentiation 1 2 2
MIRT613588 MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 2 2
MIRT616958 MAP3K7 mitogen-activated protein kinase kinase kinase 7 2 2
MIRT622619 PPP2R1B protein phosphatase 2 scaffold subunit Abeta 2 2
MIRT624015 EPHB1 EPH receptor B1 2 2
MIRT624709 APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 2 2
MIRT625797 MDC1 mediator of DNA damage checkpoint 1 2 2
MIRT627957 NLK nemo like kinase 2 2
MIRT634868 CHD4 chromodomain helicase DNA binding protein 4 2 2
MIRT635722 ALKBH4 alkB homolog 4, lysine demethylase 2 2
MIRT636107 ZBTB7A zinc finger and BTB domain containing 7A 2 2
MIRT636943 LIMS3 LIM zinc finger domain containing 3 2 2
MIRT637009 LIMS3L LIM zinc finger domain containing 4 2 2
MIRT638057 YAE1D1 Yae1 domain containing 1 2 4
MIRT640158 CDK13 cyclin dependent kinase 13 2 2
MIRT640170 ARFGEF2 ADP ribosylation factor guanine nucleotide exchange factor 2 2 2
MIRT640992 PROK2 prokineticin 2 2 2
MIRT641339 RAB11FIP1 RAB11 family interacting protein 1 2 2
MIRT642042 MAP3K2 mitogen-activated protein kinase kinase kinase 2 2 2
MIRT642074 FUT11 fucosyltransferase 11 2 2
MIRT642101 FAM84B family with sequence similarity 84 member B 2 2
MIRT642348 C19orf40 Fanconi anemia core complex associated protein 24 1 1
MIRT642583 KIAA0101 PCNA clamp associated factor 2 2
MIRT644131 TRAPPC13 trafficking protein particle complex 13 2 2
MIRT646409 HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2 2
MIRT646829 TLDC1 TBC/LysM-associated domain containing 1 2 2
MIRT648356 AKIP1 A-kinase interacting protein 1 2 2
MIRT650019 ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif 8 2 2
MIRT650602 HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 2 2
MIRT650727 TNFSF8 TNF superfamily member 8 2 2
MIRT651322 ZCCHC2 zinc finger CCHC-type containing 2 2 2
MIRT652450 TMEM236 transmembrane protein 236 2 2
MIRT652676 TIGD2 tigger transposable element derived 2 2 2
MIRT652720 TGFBRAP1 transforming growth factor beta receptor associated protein 1 2 2
MIRT653517 SLC41A1 solute carrier family 41 member 1 2 2
MIRT654405 RBBP4 RB binding protein 4, chromatin remodeling factor 2 2
MIRT654655 PSPH phosphoserine phosphatase 2 2
MIRT654943 PNRC1 proline rich nuclear receptor coactivator 1 2 2
MIRT655062 PKIA cAMP-dependent protein kinase inhibitor alpha 2 2
MIRT656554 LZIC leucine zipper and CTNNBIP1 domain containing 2 2
MIRT657666 GPR26 G protein-coupled receptor 26 2 2
MIRT659634 CDKN2AIP CDKN2A interacting protein 2 2
MIRT660584 APP amyloid beta precursor protein 2 2
MIRT664200 TBCA tubulin folding cofactor A 2 2
MIRT664577 CD44 CD44 molecule (Indian blood group) 2 2
MIRT665240 ZNF514 zinc finger protein 514 2 2
MIRT665248 ZNF362 zinc finger protein 362 2 2
MIRT666382 SHMT1 serine hydroxymethyltransferase 1 2 2
MIRT667264 NAV2 neuron navigator 2 2 2
MIRT668770 DCP2 decapping mRNA 2 2 2
MIRT668905 CREB1 cAMP responsive element binding protein 1 2 2
MIRT669411 ATP9A ATPase phospholipid transporting 9A (putative) 2 2
MIRT672667 GTF2H5 general transcription factor IIH subunit 5 2 2
MIRT675818 MAPK14 mitogen-activated protein kinase 14 2 2
MIRT690310 MRPS30 mitochondrial ribosomal protein S30 2 2
MIRT707804 TSPAN6 tetraspanin 6 2 2
MIRT709402 TADA2A transcriptional adaptor 2A 2 2
MIRT709982 RBM41 RNA binding motif protein 41 2 2
MIRT711203 SMIM14 small integral membrane protein 14 2 2
MIRT714928 ZNF264 zinc finger protein 264 2 2
MIRT717438 TENM1 teneurin transmembrane protein 1 2 2
MIRT717501 UFL1 UFM1 specific ligase 1 2 2
MIRT719812 TXNDC17 thioredoxin domain containing 17 2 2
MIRT720569 TMEM72 transmembrane protein 72 2 2
MIRT721192 FAIM3 Fc fragment of IgM receptor 1 1
MIRT721414 SEC24A SEC24 homolog A, COPII coat complex component 2 2
MIRT721575 SLC5A12 solute carrier family 5 member 12 2 2
MIRT724675 NCAPG non-SMC condensin I complex subunit G 2 2
MIRT725507 FUT9 fucosyltransferase 9 2 2
MIRT725533 EN2 engrailed homeobox 2 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-5696 Paclitaxel 36314 NSC125973 approved resistant High Ovarian Cancer cell line (SKOV3)
hsa-miR-5696 Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-5696 Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-5696 Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)

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