miRTarBase - #MIRT061598


—
pre-miRNA Information
pre-miRNA hsa-mir-6511a-1   
Genomic Coordinates chr16: 14925937 - 14926003
Description Homo sapiens miR-6511-1 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-6511a-2   
Genomic Coordinates chr16: 16324588 - 16324654
Description Homo sapiens miR-6511a-2 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-6511a-3   
Genomic Coordinates chr16: 16368876 - 16368942
Description Homo sapiens miR-6511a-3 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-6511a-4   
Genomic Coordinates chr16: 18344013 - 18344079
Description Homo sapiens miR-6511a-4 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6511a-5p
Sequence 5| CAGGCAGAAGUGGGGCUGACAGG |27
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1487543025 1 dbSNP
rs1392076032 3 dbSNP
rs1310870806 4 dbSNP
rs1254682419 4 dbSNP
rs1278331621 7 dbSNP
rs1254258380 10 dbSNP
rs1264005279 10 dbSNP
rs1422687535 10 dbSNP
rs1265836339 11 dbSNP
rs1231039877 11 dbSNP
rs778780495 11 dbSNP
rs1223241579 13 dbSNP
rs1181020448 14 dbSNP
rs1431009971 15 dbSNP
rs1356835118 21 dbSNP
rs1335107771 23 dbSNP
rs1344299836 23 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol BTG2   
Synonyms APRO1, PC3, TIS21
Description BTG anti-proliferation factor 2
Transcript NM_006763   
Expression
Putative miRNA Targets on BTG2
3'UTR of BTG2
(miRNA target sites are highlighted)		 
>BTG2|NM_006763|3'UTR
   1 GCCCTTCCGCCCCCGCCCTGGGCGCCGCCGTGCTCATGCTGCCGTGACAACAGGCCACCACATACCTCAACCTGGGGAAC
  81 TGTATTTTTAAATGAAGAGCTATTTATATATATTATTTTTTTTTAAGAAAGGAGGAAAAGAAACCAAAAGTTTTTTTTAA
 161 GAAAAAAAATCCTTCAAGGGAGCTGCTTGGAAGTGGCCTCCCCAGGTGCCTTTGGAGAGAACTGTTGCGTGCTTGAGTCT
 241 GTGAGCCAGTGTCTGCCTATAGGAGGGGGAGCTGTTAGGGGGTAGACCTAGCCAAGGAGAAGTGGGAGACGTTTGGCTAG
 321 CACCCCAGGAAGATGTGAGAGGGAGCAAGCAAGGTTAGCAACTGTGAACAGAGAGGTCGGGATTTGCCCTGGGGGAGGAA
 401 GAGAGGCCAAGTTCAGAGCTCTCTGTCTCCCCCAGCCAGACACCTGCATCCCTGGCTCCTCTATTACTCAGGGGCATTCA
 481 TGCCTGGACTTAAACAATACTATGTTATCTTTTCTTTTATTTTTCTAATGAGGTCCTGGGCAGAGAGTGAAAAGGCCTCT
 561 CCTGATTCCTACTGTCCTAAGCTGCTTTTCTTGAAATCATGACTTGTTTCTAATTCTACCCTCAGGGGCCTGTAGATGTT
 641 GCTTTCCAGCCAGGAATCTAAAGCTTTGGGTTTTCTGAGGGGGGGGAGGAGGGAACTGGAGGTTATTGGGGTTAGGATGG
 721 AAGGGAACTCTGCACAAAACCTTTGCTTTGCTAGTGCTGCTTTGTGTGTATGTGTGGCAAATAATTTGGGGGTGATTTGC
 801 AATGAAATTTTGGGACCCAAAGAGTATCCACTGGGGATGTTTTTTGGCCAAAACTCTTCCTTTTGGAACCACATGAAAGT
 881 CTTGATGCTGCTGCCATGATCCCTTTGAGAGGTGGCTCAAAAGCTACAGGGAACTCCAGGTCCTTTATTACTGCCTTCTT
 961 TTCAAAAGCACAACTCTCCTCTAACCCTCCCCTCCCCCTTCCCTTCTGGTCGGGTCATAGAGCTACCGTATTTTCTAGGA
1041 CAAGAGTTCTCAGTCACTGTGCAATATGCCCCCTGGGTCCCAGGAGGGTCTGGAGGAAAACTGGCTATCAGAACCTCCTG
1121 ATGCCCTGGTGGGCTTAGGGAACCATCTCTCCTGCTCTCCTTGGGATGATGGCTGGCTAGTCAGCCTTGCATGTATTCCT
1201 TGGCTGAATGGGAGAGTGCCCCATGTTCTGCAAGACTACTTGGTATTCTTGTAGGGCCGACACTAAATAAAAGCCAAACC
1281 TTGGGCACTGTTTTTTCTCCCTGGTGCTCAGAGCACCTGTGGGAAAGGTTGCTGTCTGTCTCAGTACAATCCAAATTTGT
1361 CGTAGACTTGTGCAATATATACTGTTGTGGGTTGGAGAAAAGTGGAAAGCTACACTGGGAAGAAACTCCCTTCCTTCAAT
1441 TTCTCAGTGACATTGATGAGGGGTCCTCAAAAGACCTCGAGTTTCCCAAACCGAATCACCTTAAGAAGGACAGGGCTAGG
1521 GCATTTGGCCAGGATGGCCACCCTCCTGCTGTTGCCCCTTAGTGAGGAATCTTCACCCCACTTCCTCTACCCCCAGGTTC
1601 TCCTCCCCACAGCCAGTCCCCTTTCCTGGATTTCTAAACTGCTCAATTTTGACTCAAAGGTGCTATTTACCAAACACTCT
1681 CCCTACCCATTCCTGCCAGCTCTGCCTCCTTTTCAACTCTCCACATTTTGTATTGCCTTCCCAGACCTGCTTCCAGTCTT
1761 TATTGCTTTAAAGTTCACTTTGGGCCCACAGACCCAAGAGCTAATTTTCTGGTTTGTGGGTTGAAACAAAGCTGTGAATC
1841 ACTGCAGGCTGTGTTCTTGCATCTTGTCTGCAAACAGGTCCCTGCCTTTTTAGAAGCAGCCTCATGGTCTCATGCTTAAT
1921 CTTGTCTCTCTTCTCTTCTTTATGATGTTCACTTTAAAAACAACAAAACCCCTGAGCTGGACTGTTGAGCAGGCCTGTCT
2001 CTCCTATTAAGTAAAAATAAATAGTAGTAGTATGTTTGTAAGCTATTCTGACAGAAAAGACAAAGGTTACTAATTGTATG
2081 ATAGTGTTTTTATATGGAAGAATGTACAGCTTATGGACAAATGTACACCTTTTTGTTACTTTAATAAAAATGTAGTAGGA
2161 TAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ggACAGUCGGGGUGA-AGACGGAc 5'
            ||| ||  ||| | ||||||| 
Target 5' tcTGTGAG--CCAGTGTCTGCCTa 3'
 238 - 259 161.00 -23.90
2 
miRNA  3' ggacaGUCGG---GGUGAAGACGGAc 5'
               || :|   |||  ||||||| 
Target 5' ctaccCATTCCTGCCAGCTCTGCCTc 3'
 1683 - 1708 150.00 -19.40
3 
miRNA  3' ggacAGUCGGGGUGAAGACGGAc 5'
              ||||  |: | ||||:|| 
Target 5' aagtTCAGAGCT-C-TCTGTCTc 3'
 409 - 429 133.00 -13.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31521048 5 COSMIC
COSN30150327 14 COSMIC
COSN30529015 25 COSMIC
COSN30151598 27 COSMIC
COSN31505873 33 COSMIC
COSN30153261 69 COSMIC
COSN25480150 97 COSMIC
COSN25447161 101 COSMIC
COSN26504475 111 COSMIC
COSN31769502 112 COSMIC
COSN18724448 125 COSMIC
COSN31595827 178 COSMIC
COSN26504601 190 COSMIC
COSN31769503 344 COSMIC
COSN31543119 515 COSMIC
COSN9057026 527 COSMIC
COSN24520822 672 COSMIC
COSN20095823 687 COSMIC
COSN21469439 717 COSMIC
COSN26585385 733 COSMIC
COSN28363909 846 COSMIC
COSN21538062 863 COSMIC
COSN19405058 959 COSMIC
COSN31769505 1024 COSMIC
COSN31541478 1069 COSMIC
COSN26249695 1114 COSMIC
COSN18723901 1139 COSMIC
COSN31769506 1229 COSMIC
COSN30538366 1281 COSMIC
COSN31514034 1362 COSMIC
COSN31960380 1363 COSMIC
COSN31542781 1444 COSMIC
COSN31556057 1528 COSMIC
COSN31514401 1616 COSMIC
COSN1427020 1987 COSMIC
COSN17183007 2003 COSMIC
COSN31522292 2017 COSMIC
COSN22877916 2031 COSMIC
COSN28742730 2051 COSMIC
COSN28742953 2055 COSMIC
COSN30545449 2083 COSMIC
COSN25648869 2157 COSMIC
rs538260231 840 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1342422747 1 dbSNP
rs1415494436 3 dbSNP
rs1292812622 8 dbSNP
rs369785815 9 dbSNP
rs769970472 9 dbSNP
rs1208400964 10 dbSNP
rs756195828 10 dbSNP
rs766409214 11 dbSNP
rs755200538 12 dbSNP
rs1252949151 14 dbSNP
rs201462115 15 dbSNP
rs778326561 16 dbSNP
rs747522944 17 dbSNP
rs1486481294 18 dbSNP
rs770448408 19 dbSNP
rs776081022 23 dbSNP
rs745407928 27 dbSNP
rs1173193600 28 dbSNP
rs543409078 30 dbSNP
rs1461802405 31 dbSNP
rs762803619 33 dbSNP
rs763854059 36 dbSNP
rs936449734 37 dbSNP
rs774313207 42 dbSNP
rs767547740 44 dbSNP
rs563817102 45 dbSNP
rs755110487 46 dbSNP
rs773541040 47 dbSNP
rs765548346 52 dbSNP
rs906436597 55 dbSNP
rs1199712110 59 dbSNP
rs1247926585 67 dbSNP
rs532470883 71 dbSNP
rs933030925 78 dbSNP
rs1051849698 82 dbSNP
rs140561243 86 dbSNP
rs1457094179 87 dbSNP
rs565056217 93 dbSNP
rs1176380139 95 dbSNP
rs963203697 105 dbSNP
rs1004884523 108 dbSNP
rs569803446 115 dbSNP
rs762792320 116 dbSNP
rs954227723 116 dbSNP
rs985410906 116 dbSNP
rs912533319 121 dbSNP
rs1162613918 125 dbSNP
rs1413585176 136 dbSNP
rs965616805 145 dbSNP
rs1175971162 151 dbSNP
rs1454970746 151 dbSNP
rs1411600226 152 dbSNP
rs1476640311 162 dbSNP
rs978272725 162 dbSNP
rs145883516 165 dbSNP
rs936847166 169 dbSNP
rs1440961715 171 dbSNP
rs1399264379 174 dbSNP
rs1053984478 179 dbSNP
rs1348328691 181 dbSNP
rs1296526375 182 dbSNP
rs916313721 186 dbSNP
rs547719210 188 dbSNP
rs1444862686 194 dbSNP
rs1363940035 196 dbSNP
rs1336331419 201 dbSNP
rs898672572 208 dbSNP
rs947729519 214 dbSNP
rs1373298742 225 dbSNP
rs1046110576 228 dbSNP
rs995631283 229 dbSNP
rs1033761366 230 dbSNP
rs758798143 246 dbSNP
rs1004806296 247 dbSNP
rs959428702 261 dbSNP
rs1342974852 262 dbSNP
rs1036248225 269 dbSNP
rs1420823240 275 dbSNP
rs1013646072 279 dbSNP
rs1025406868 280 dbSNP
rs1259624705 312 dbSNP
rs994680486 313 dbSNP
rs1027510113 318 dbSNP
rs966699402 322 dbSNP
rs978416154 323 dbSNP
rs1202139199 325 dbSNP
rs1032258304 331 dbSNP
rs1309235641 336 dbSNP
rs954117248 342 dbSNP
rs1227308001 345 dbSNP
rs1006904171 349 dbSNP
rs1294529446 350 dbSNP
rs1415039233 370 dbSNP
rs957890041 372 dbSNP
rs1193720570 379 dbSNP
rs1444801008 380 dbSNP
rs1355701317 385 dbSNP
rs764489531 386 dbSNP
rs965313920 393 dbSNP
rs921705144 398 dbSNP
rs1420145246 399 dbSNP
rs776568889 404 dbSNP
rs933084594 415 dbSNP
rs567527162 422 dbSNP
rs12063729 433 dbSNP
rs907540815 434 dbSNP
rs1175323760 438 dbSNP
rs1478797289 441 dbSNP
rs1481490113 456 dbSNP
rs924214392 462 dbSNP
rs757491327 464 dbSNP
rs549485940 467 dbSNP
rs1274536514 468 dbSNP
rs1233343089 479 dbSNP
rs781339681 480 dbSNP
rs989650667 483 dbSNP
rs12085417 488 dbSNP
rs898744550 489 dbSNP
rs1374525331 500 dbSNP
rs1293254474 509 dbSNP
rs1403237512 520 dbSNP
rs931502952 520 dbSNP
rs1414087234 529 dbSNP
rs1326719417 533 dbSNP
rs538341532 541 dbSNP
rs1161560915 543 dbSNP
rs927622295 556 dbSNP
rs1408464372 557 dbSNP
rs1190368386 560 dbSNP
rs1467112679 561 dbSNP
rs1362524690 573 dbSNP
rs1213848868 574 dbSNP
rs1401156879 576 dbSNP
rs1258373861 578 dbSNP
rs375702332 580 dbSNP
rs1036729864 582 dbSNP
rs1317100154 583 dbSNP
rs1338934969 586 dbSNP
rs895285769 594 dbSNP
rs756202846 600 dbSNP
rs1014091948 601 dbSNP
rs138492634 603 dbSNP
rs1345362987 604 dbSNP
rs1382893444 617 dbSNP
rs902551369 621 dbSNP
rs1290654666 624 dbSNP
rs1006935143 637 dbSNP
rs888907302 637 dbSNP
rs572300436 643 dbSNP
rs1452338551 645 dbSNP
rs1488947959 647 dbSNP
rs778779331 652 dbSNP
rs1217290640 661 dbSNP
rs1427800104 666 dbSNP
rs1259095055 669 dbSNP
rs1206353731 673 dbSNP
rs202052540 678 dbSNP
rs957924099 678 dbSNP
rs1255035741 679 dbSNP
rs373717932 679 dbSNP
rs397736594 679 dbSNP
rs573875025 679 dbSNP
rs5780160 679 dbSNP
rs761729330 679 dbSNP
rs766982614 679 dbSNP
rs1491142379 680 dbSNP
rs56048832 680 dbSNP
rs1382823313 681 dbSNP
rs373538301 681 dbSNP
rs974635442 681 dbSNP
rs1491495525 682 dbSNP
rs3795582 682 dbSNP
rs114151974 683 dbSNP
rs1194770520 684 dbSNP
rs1377981147 685 dbSNP
rs1185363200 686 dbSNP
rs200299376 687 dbSNP
rs78869403 688 dbSNP
rs554848532 689 dbSNP
rs1281527839 702 dbSNP
rs1477855717 707 dbSNP
rs1195557237 719 dbSNP
rs990116670 724 dbSNP
rs907617206 726 dbSNP
rs1253594206 728 dbSNP
rs567587943 734 dbSNP
rs1023812316 745 dbSNP
rs752497704 747 dbSNP
rs574754503 752 dbSNP
rs1420339586 766 dbSNP
rs1297635051 771 dbSNP
rs113918784 781 dbSNP
rs367900254 782 dbSNP
rs1359232067 785 dbSNP
rs973031183 793 dbSNP
rs1416893655 800 dbSNP
rs543820952 810 dbSNP
rs1356307587 813 dbSNP
rs1313315239 826 dbSNP
rs1340452648 840 dbSNP
rs538260231 840 dbSNP
rs1394327930 842 dbSNP
rs931576651 854 dbSNP
rs1330830373 869 dbSNP
rs940363937 880 dbSNP
rs187962637 881 dbSNP
rs545970390 887 dbSNP
rs971745609 889 dbSNP
rs1162123158 897 dbSNP
rs771948296 909 dbSNP
rs1232088075 910 dbSNP
rs920227831 912 dbSNP
rs1181611565 917 dbSNP
rs1300759292 924 dbSNP
rs1436437516 926 dbSNP
rs930578614 927 dbSNP
rs1055268117 928 dbSNP
rs1355252536 929 dbSNP
rs1050734473 943 dbSNP
rs888980781 948 dbSNP
rs1235193012 952 dbSNP
rs1240299840 954 dbSNP
rs1335806105 955 dbSNP
rs944538045 957 dbSNP
rs1284643147 975 dbSNP
rs895305020 976 dbSNP
rs949576195 979 dbSNP
rs866232134 980 dbSNP
rs76519638 982 dbSNP
rs901252679 987 dbSNP
rs1391925783 990 dbSNP
rs1323365327 991 dbSNP
rs1046951321 994 dbSNP
rs1417870753 999 dbSNP
rs1157651073 1002 dbSNP
rs866825510 1003 dbSNP
rs141109235 1005 dbSNP
rs1365946027 1009 dbSNP
rs1211551500 1011 dbSNP
rs527493467 1012 dbSNP
rs547581235 1013 dbSNP
rs1215708551 1030 dbSNP
rs1468967361 1046 dbSNP
rs893760446 1049 dbSNP
rs1450755806 1050 dbSNP
rs1192018006 1051 dbSNP
rs1353060644 1059 dbSNP
rs1281110570 1061 dbSNP
rs1011165573 1062 dbSNP
rs372059695 1073 dbSNP
rs561189406 1082 dbSNP
rs868624412 1091 dbSNP
rs1032362748 1095 dbSNP
rs893784024 1096 dbSNP
rs1442941508 1097 dbSNP
rs1158196119 1107 dbSNP
rs1394611879 1108 dbSNP
rs1316971359 1115 dbSNP
rs1398635080 1124 dbSNP
rs1386661423 1125 dbSNP
rs1159570530 1127 dbSNP
rs1454106010 1128 dbSNP
rs746844675 1134 dbSNP
rs1196065370 1137 dbSNP
rs529927417 1140 dbSNP
rs556563281 1141 dbSNP
rs954744107 1144 dbSNP
rs756143754 1146 dbSNP
rs969586109 1146 dbSNP
rs1385407406 1155 dbSNP
rs1333757543 1163 dbSNP
rs191529784 1166 dbSNP
rs1285200870 1177 dbSNP
rs16851280 1178 dbSNP
rs1346902406 1181 dbSNP
rs1447052069 1187 dbSNP
rs1034798235 1192 dbSNP
rs1236446426 1194 dbSNP
rs1368175842 1199 dbSNP
rs1307966125 1200 dbSNP
rs1314552842 1203 dbSNP
rs374313138 1209 dbSNP
rs11586635 1212 dbSNP
rs961837311 1225 dbSNP
rs1327904585 1226 dbSNP
rs973096507 1232 dbSNP
rs920279956 1233 dbSNP
rs879162712 1240 dbSNP
rs1175874302 1244 dbSNP
rs989693507 1251 dbSNP
rs1419398419 1252 dbSNP
rs565394831 1259 dbSNP
rs1476429420 1260 dbSNP
rs910451465 1263 dbSNP
rs1187531171 1267 dbSNP
rs1239774023 1275 dbSNP
rs1458428748 1281 dbSNP
rs764873286 1288 dbSNP
rs1178198891 1297 dbSNP
rs534900693 1308 dbSNP
rs60342861 1310 dbSNP
rs916830474 1314 dbSNP
rs1212670162 1320 dbSNP
rs1340875696 1327 dbSNP
rs1166142148 1329 dbSNP
rs1278220051 1331 dbSNP
rs538887336 1332 dbSNP
rs1353142674 1333 dbSNP
rs949610709 1335 dbSNP
rs373141560 1337 dbSNP
rs1173352752 1348 dbSNP
rs1401460490 1362 dbSNP
rs1046540553 1363 dbSNP
rs924082329 1380 dbSNP
rs924422721 1398 dbSNP
rs780900419 1399 dbSNP
rs1164264463 1400 dbSNP
rs935433642 1403 dbSNP
rs935417653 1404 dbSNP
rs1189891303 1406 dbSNP
rs1483458733 1422 dbSNP
rs1330187720 1429 dbSNP
rs893841088 1432 dbSNP
rs1370577976 1439 dbSNP
rs1397216438 1440 dbSNP
rs1439447292 1442 dbSNP
rs1258183729 1444 dbSNP
rs1232122716 1448 dbSNP
rs1332297469 1449 dbSNP
rs1312771332 1458 dbSNP
rs1228469632 1461 dbSNP
rs1011322751 1462 dbSNP
rs1296771709 1466 dbSNP
rs1045367507 1469 dbSNP
rs575103998 1471 dbSNP
rs1339874690 1474 dbSNP
rs1325375497 1475 dbSNP
rs367892990 1479 dbSNP
rs905432979 1487 dbSNP
rs150236063 1493 dbSNP
rs763532512 1494 dbSNP
rs1407016424 1500 dbSNP
rs1175230744 1506 dbSNP
rs537329168 1509 dbSNP
rs1035206494 1515 dbSNP
rs745825418 1516 dbSNP
rs993294068 1521 dbSNP
rs1466752168 1533 dbSNP
rs557364252 1543 dbSNP
rs1274440494 1546 dbSNP
rs1213773374 1552 dbSNP
rs764567961 1553 dbSNP
rs577164404 1555 dbSNP
rs1303325329 1561 dbSNP
rs1255549733 1578 dbSNP
rs1396815564 1579 dbSNP
rs751564630 1580 dbSNP
rs572194545 1586 dbSNP
rs1009172053 1588 dbSNP
rs1196394152 1593 dbSNP
rs1014771219 1598 dbSNP
rs751952792 1603 dbSNP
rs78959463 1605 dbSNP
rs961818211 1609 dbSNP
rs994546782 1612 dbSNP
rs965952000 1620 dbSNP
rs1477675831 1622 dbSNP
rs796923660 1623 dbSNP
rs924477815 1627 dbSNP
rs1452443977 1655 dbSNP
rs958398989 1656 dbSNP
rs1254381834 1661 dbSNP
rs138699312 1670 dbSNP
rs1197667329 1672 dbSNP
rs866592912 1678 dbSNP
rs916839540 1679 dbSNP
rs1302980947 1683 dbSNP
rs915295201 1684 dbSNP
rs546139031 1686 dbSNP
rs771868400 1696 dbSNP
rs982744230 1709 dbSNP
rs762091614 1718 dbSNP
rs34345774 1721 dbSNP
rs1045104382 1724 dbSNP
rs1302123747 1725 dbSNP
rs1381703378 1731 dbSNP
rs905172671 1732 dbSNP
rs1412865713 1742 dbSNP
rs924142453 1754 dbSNP
rs1003803880 1755 dbSNP
rs1360955063 1756 dbSNP
rs1056722020 1764 dbSNP
rs1432841192 1765 dbSNP
rs1379285094 1771 dbSNP
rs1176239506 1775 dbSNP
rs1340922361 1777 dbSNP
rs935447347 1779 dbSNP
rs74137610 1780 dbSNP
rs1258991917 1789 dbSNP
rs34050060 1793 dbSNP
rs915323112 1813 dbSNP
rs1195429330 1820 dbSNP
rs1804736 1827 dbSNP
rs994052335 1837 dbSNP
rs1257304172 1847 dbSNP
rs1209146587 1848 dbSNP
rs1027434552 1860 dbSNP
rs1293141846 1865 dbSNP
rs951899429 1877 dbSNP
rs1227253490 1878 dbSNP
rs1007239467 1898 dbSNP
rs932000782 1899 dbSNP
rs1050432580 1902 dbSNP
rs1312114494 1903 dbSNP
rs915452021 1905 dbSNP
rs1804735 1906 dbSNP
rs1804737 1910 dbSNP
rs76416255 1919 dbSNP
rs1303374688 1943 dbSNP
rs1036647023 1944 dbSNP
rs1370877624 1956 dbSNP
rs965650259 1957 dbSNP
rs1484693145 1973 dbSNP
rs1416695775 1978 dbSNP
rs117103442 1991 dbSNP
rs138896134 1994 dbSNP
rs750671916 1995 dbSNP
rs1195753538 2007 dbSNP
rs1488236757 2020 dbSNP
rs1027389725 2022 dbSNP
rs879123876 2022 dbSNP
rs1334526222 2028 dbSNP
rs955923031 2028 dbSNP
rs1291675011 2029 dbSNP
rs1185214618 2031 dbSNP
rs990378187 2031 dbSNP
rs1427684462 2034 dbSNP
rs1313116199 2035 dbSNP
rs1804734 2041 dbSNP
rs561049519 2045 dbSNP
rs1130691 2049 dbSNP
rs1013057121 2055 dbSNP
rs1394216968 2059 dbSNP
rs567153308 2059 dbSNP
rs1023988259 2060 dbSNP
rs971436989 2070 dbSNP
rs756366363 2076 dbSNP
rs1473545899 2081 dbSNP
rs780081453 2085 dbSNP
rs1369440413 2093 dbSNP
rs530047112 2096 dbSNP
rs1417914540 2105 dbSNP
rs1240568092 2106 dbSNP
rs1031668907 2115 dbSNP
rs1393991304 2119 dbSNP
rs956894363 2124 dbSNP
rs989637128 2127 dbSNP
rs1056739357 2129 dbSNP
rs915352873 2142 dbSNP
rs932074289 2151 dbSNP
rs986585315 2156 dbSNP
rs898056851 2158 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions C8166
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462572. RNA binding protein: AGO2. Condition:C8166 NL4-3 ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ggacagucggGGUGAAGACGGAc 5'
                    |||  ||||||| 
Target 5' ----------CCAGCUCUGCCUc 3'
 		1 - 13
2 
miRNA  3' ggACAGU--CGGGGUG-AAGACGGAc 5'
            | |||   |:|||| ||:||: | 
Target 5' cuUUUCAACUCUCCACAUUUUGUAUu 3'
 		14 - 39
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HCT116
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in ERX177612. RNA binding protein: AGO2. Condition:p53_V_AGO_CLIP_3_2 PAR-CLIP data was present in ERX177624. RNA binding protein: AGO2. Condition:p53_V_AGO_CLIP_4_2 PAR-CLIP data was present in ERX177616. RNA binding protein: AGO2. Condition:p53_V_AGO_CLIP_3_6 ...

- Krell J; Stebbing J; Carissimi C; Dabrowska et al., 2016, Genome research.

Article - Krell J; Stebbing J; Carissimi C; Dabrowska et al.
- Genome research, 2016
DNA damage activates TP53-regulated surveillance mechanisms that are crucial in suppressing tumorigenesis. TP53 orchestrates these responses directly by transcriptionally modulating genes, including microRNAs (miRNAs), and by regulating miRNA biogenesis through interacting with the DROSHA complex. However, whether the association between miRNAs and AGO2 is regulated following DNA damage is not yet known. Here, we show that, following DNA damage, TP53 interacts with AGO2 to induce or reduce AGO2's association of a subset of miRNAs, including multiple let-7 family members. Furthermore, we show that specific mutations in TP53 decrease rather than increase the association of let-7 family miRNAs, reducing their activity without preventing TP53 from interacting with AGO2. This is consistent with the oncogenic properties of these mutants. Using AGO2 RIP-seq and PAR-CLIP-seq, we show that the DNA damage-induced increase in binding of let-7 family members to the RISC complex is functional. We unambiguously determine the global miRNA-mRNA interaction networks involved in the DNA damage response, validating them through the identification of miRNA-target chimeras formed by endogenous ligation reactions. We find that the target complementary region of the let-7 seed tends to have highly fixed positions and more variable ones. Additionally, we observe that miRNAs, whose cellular abundance or differential association with AGO2 is regulated by TP53, are involved in an intricate network of regulatory feedback and feedforward circuits. TP53-mediated regulation of AGO2-miRNA interaction represents a new mechanism of miRNA regulation in carcinogenesis.
LinkOut: [PMID: 26701625]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions Prostate Tissue
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in SRX1760597. RNA binding protein: AGO2. Condition:AGO-CLIP-LNCaP_C ...

- Hamilton MP; Rajapakshe KI; Bader DA; Cerne et al., 2016, Neoplasia (New York, N.Y.).

Article - Hamilton MP; Rajapakshe KI; Bader DA; Cerne et al.
- Neoplasia (New York, N.Y.), 2016
MicroRNA (miRNA) deregulation in prostate cancer (PCa) contributes to PCa initiation and metastatic progression. To comprehensively define the cancer-associated changes in miRNA targeting and function in commonly studied models of PCa, we performed photoactivatable ribonucleoside-enhanced cross-linking immunoprecipitation of the Argonaute protein in a panel of PCa cell lines modeling different stages of PCa progression. Using this comprehensive catalogue of miRNA targets, we analyzed miRNA targeting on known drivers of PCa and examined tissue-specific and stage-specific pathway targeting by miRNAs. We found that androgen receptor is the most frequently targeted PCa oncogene and that miR-148a targets the largest number of known PCa drivers. Globally, tissue-specific and stage-specific changes in miRNA targeting are driven by homeostatic response to active oncogenic pathways. Our findings indicate that, even in advanced PCa, the miRNA pool adapts to regulate continuing alterations in the cancer genome to balance oncogenic molecular changes. These findings are important because they are the first to globally characterize miRNA changes in PCa and demonstrate how the miRNA target spectrum responds to staged tumorigenesis.
LinkOut: [PMID: 27292025]
CLIP-seq Support 1 for dataset GSM1462572
Method / RBP PAR-CLIP / AGO2
Cell line / Condition C8166 / C8166 NL4-3
Location of target site ENST00000290551.4 | 3UTR | CCAGCUCUGCCUCCUUUUCAACUCUCCACAUUUUGUAUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
303 hsa-miR-6511a-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT061598 BTG2 BTG anti-proliferation factor 2 2 2
MIRT065800 HOXC8 homeobox C8 2 6
MIRT070739 HIF1A hypoxia inducible factor 1 alpha subunit 2 2
MIRT073283 IREB2 iron responsive element binding protein 2 2 2
MIRT079374 CCDC137 coiled-coil domain containing 137 2 2
MIRT088059 UBXN2A UBX domain protein 2A 2 4
MIRT145629 LASP1 LIM and SH3 protein 1 2 2
MIRT152258 ZNF460 zinc finger protein 460 2 8
MIRT192135 PAPOLA poly(A) polymerase alpha 2 2
MIRT197663 DHX40 DEAH-box helicase 40 2 2
MIRT224280 FAM91A1 family with sequence similarity 91 member A1 2 4
MIRT246475 ZBTB7B zinc finger and BTB domain containing 7B 2 2
MIRT246680 UHMK1 U2AF homology motif kinase 1 2 2
MIRT254106 PLEKHB2 pleckstrin homology domain containing B2 2 2
MIRT282637 IGF1R insulin like growth factor 1 receptor 2 4
MIRT307058 TGFBR2 transforming growth factor beta receptor 2 2 2
MIRT310365 PDGFRA platelet derived growth factor receptor alpha 2 4
MIRT317937 SLC29A1 solute carrier family 29 member 1 (Augustine blood group) 2 2
MIRT353111 PIM3 Pim-3 proto-oncogene, serine/threonine kinase 2 2
MIRT370516 ZNRF3 zinc and ring finger 3 2 2
MIRT377075 SLC35F6 solute carrier family 35 member F6 2 2
MIRT395058 TNFAIP2 TNF alpha induced protein 2 2 2
MIRT443679 HSD17B12 hydroxysteroid 17-beta dehydrogenase 12 2 6
MIRT446960 ZNF431 zinc finger protein 431 2 2
MIRT447172 MFSD8 major facilitator superfamily domain containing 8 2 2
MIRT449417 TMEM106B transmembrane protein 106B 2 2
MIRT451118 RPS19 ribosomal protein S19 2 2
MIRT451352 ZNF573 zinc finger protein 573 2 4
MIRT451984 FKBP5 FK506 binding protein 5 2 2
MIRT452225 HAVCR1 hepatitis A virus cellular receptor 1 2 8
MIRT452288 CARD8 caspase recruitment domain family member 8 2 2
MIRT452348 TG thyroglobulin 2 2
MIRT452402 TTC39B tetratricopeptide repeat domain 39B 2 2
MIRT452521 TFDP2 transcription factor Dp-2 2 6
MIRT452900 PSD4 pleckstrin and Sec7 domain containing 4 2 4
MIRT453032 ZNF527 zinc finger protein 527 2 4
MIRT453177 CNOT4 CCR4-NOT transcription complex subunit 4 2 6
MIRT453203 ZNF589 zinc finger protein 589 2 4
MIRT453319 ZNF394 zinc finger protein 394 2 2
MIRT453568 RDH13 retinol dehydrogenase 13 2 2
MIRT453917 GABRR2 gamma-aminobutyric acid type A receptor rho2 subunit 2 4
MIRT453931 COMMD5 COMM domain containing 5 2 4
MIRT454103 TMEM209 transmembrane protein 209 2 2
MIRT454410 AKAP5 A-kinase anchoring protein 5 2 2
MIRT454578 NT5DC3 5'-nucleotidase domain containing 3 2 2
MIRT455490 NPY4R neuropeptide Y receptor Y4 2 2
MIRT455694 GLO1 glyoxalase I 2 2
MIRT455798 TAF8 TATA-box binding protein associated factor 8 2 2
MIRT455813 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT455939 SURF6 surfeit 6 2 2
MIRT456667 TIFA TRAF interacting protein with forkhead associated domain 2 2
MIRT456807 SIGLEC14 sialic acid binding Ig like lectin 14 2 2
MIRT457006 ZNF669 zinc finger protein 669 2 2
MIRT457090 XPNPEP3 X-prolyl aminopeptidase 3 2 2
MIRT457124 APOLD1 apolipoprotein L domain containing 1 2 2
MIRT457324 DUSP19 dual specificity phosphatase 19 2 4
MIRT457554 ZC3H6 zinc finger CCCH-type containing 6 2 2
MIRT457646 ZNF69 zinc finger protein 69 2 2
MIRT458090 C8orf33 chromosome 8 open reading frame 33 2 2
MIRT458145 TLCD2 TLC domain containing 2 2 2
MIRT458162 LYRM4 LYR motif containing 4 2 6
MIRT458198 ATP6V0A2 ATPase H+ transporting V0 subunit a2 2 2
MIRT458565 C10orf71 chromosome 10 open reading frame 71 2 2
MIRT458624 TRIM72 tripartite motif containing 72 2 4
MIRT458655 SGPP2 sphingosine-1-phosphate phosphatase 2 2 2
MIRT458806 CYP8B1 cytochrome P450 family 8 subfamily B member 1 2 2
MIRT458903 PFAS phosphoribosylformylglycinamidine synthase 2 6
MIRT459043 ZNF490 zinc finger protein 490 2 4
MIRT459136 FADS6 fatty acid desaturase 6 2 2
MIRT459157 NARF nuclear prelamin A recognition factor 2 4
MIRT459185 HSPA6 heat shock protein family A (Hsp70) member 6 2 4
MIRT459375 MPLKIP M-phase specific PLK1 interacting protein 2 6
MIRT459432 FAM83B family with sequence similarity 83 member B 2 2
MIRT459763 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT459862 SVOP SV2 related protein 2 8
MIRT460048 CDCP1 CUB domain containing protein 1 2 4
MIRT460240 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT460253 IL17RB interleukin 17 receptor B 2 4
MIRT460388 GUF1 GUF1 homolog, GTPase 2 4
MIRT460521 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT460984 STK17B serine/threonine kinase 17b 2 2
MIRT461050 DCPS decapping enzyme, scavenger 2 4
MIRT461145 ZNF264 zinc finger protein 264 2 2
MIRT461216 TIPIN TIMELESS interacting protein 2 2
MIRT461409 SLFN12L schlafen family member 12 like 2 10
MIRT461422 CTSL2 cathepsin V 1 1
MIRT461446 ACSBG1 acyl-CoA synthetase bubblegum family member 1 2 2
MIRT461513 NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 2 2
MIRT461871 ZNF317 zinc finger protein 317 2 2
MIRT461898 NECAB3 N-terminal EF-hand calcium binding protein 3 2 2
MIRT462228 NUP155 nucleoporin 155 2 4
MIRT462495 GSR glutathione-disulfide reductase 2 2
MIRT462530 DHODH dihydroorotate dehydrogenase (quinone) 2 6
MIRT462622 C20orf27 chromosome 20 open reading frame 27 2 4
MIRT462867 CYP51A1 cytochrome P450 family 51 subfamily A member 1 2 2
MIRT463024 ZNF70 zinc finger protein 70 2 2
MIRT463047 ZNF689 zinc finger protein 689 2 2
MIRT463080 ZNF639 zinc finger protein 639 2 2
MIRT463131 ZNF451 zinc finger protein 451 2 4
MIRT463364 ZFAND4 zinc finger AN1-type containing 4 2 2
MIRT463822 XKR4 XK related 4 2 2
MIRT464362 USP12P1 ubiquitin specific peptidase 12 pseudogene 1 2 2
MIRT464450 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT464537 UBTF upstream binding transcription factor, RNA polymerase I 2 2
MIRT464771 UBE2G1 ubiquitin conjugating enzyme E2 G1 2 2
MIRT465332 TPM3 tropomyosin 3 2 2
MIRT465533 PRICKLE4 prickle planar cell polarity protein 4 2 2
MIRT466098 TMEM184C transmembrane protein 184C 2 2
MIRT467092 SRRD SRR1 domain containing 2 2
MIRT467262 SPPL2A signal peptide peptidase like 2A 2 2
MIRT467545 SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 2 2
MIRT468585 SERBP1 SERPINE1 mRNA binding protein 1 2 6
MIRT469039 RNF38 ring finger protein 38 2 6
MIRT469688 RAB5B RAB5B, member RAS oncogene family 2 2
MIRT469968 PTPRF protein tyrosine phosphatase, receptor type F 2 2
MIRT470510 PPP1R11 protein phosphatase 1 regulatory inhibitor subunit 11 2 2
MIRT471145 PHF19 PHD finger protein 19 2 2
MIRT471238 PHAX phosphorylated adaptor for RNA export 2 2
MIRT471654 PANK2 pantothenate kinase 2 2 4
MIRT472112 NME2 NME/NM23 nucleoside diphosphate kinase 2 2 2
MIRT472129 NME1-NME2 NME1-NME2 readthrough 2 2
MIRT472504 NACC2 NACC family member 2 2 2
MIRT472879 MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 2
MIRT472968 MSANTD3 Myb/SANT DNA binding domain containing 3 2 2
MIRT473024 MRPS14 mitochondrial ribosomal protein S14 2 2
MIRT473085 MORN4 MORN repeat containing 4 2 2
MIRT474102 LMBR1L limb development membrane protein 1 like 2 2
MIRT474123 LIPC lipase C, hepatic type 2 2
MIRT474893 KCTD5 potassium channel tetramerization domain containing 5 2 2
MIRT475506 HSP90B1 heat shock protein 90 beta family member 1 2 4
MIRT476417 GDE1 glycerophosphodiester phosphodiesterase 1 2 8
MIRT477239 ETF1 eukaryotic translation termination factor 1 2 2
MIRT478007 DNAL1 dynein axonemal light chain 1 2 2
MIRT478306 DDX19A DEAD-box helicase 19A 2 6
MIRT478864 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT479182 CLSPN claspin 2 2
MIRT479433 CDKN1B cyclin dependent kinase inhibitor 1B 2 8
MIRT479549 CDC5L cell division cycle 5 like 2 4
MIRT479672 CCSER2 coiled-coil serine rich protein 2 2 2
MIRT479786 CCND1 cyclin D1 2 2
MIRT480737 BPTF bromodomain PHD finger transcription factor 2 6
MIRT481578 ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 2 2
MIRT481707 AR androgen receptor 2 2
MIRT482502 ACTR1A ARP1 actin related protein 1 homolog A 2 2
MIRT484908 ZFYVE26 zinc finger FYVE-type containing 26 2 4
MIRT486077 ARPP19 cAMP regulated phosphoprotein 19 2 4
MIRT487020 C2orf82 chromosome 2 open reading frame 82 2 2
MIRT487472 ANKRD42 ankyrin repeat domain 42 2 2
MIRT488741 ASGR2 asialoglycoprotein receptor 2 2 4
MIRT489516 CRLF3 cytokine receptor like factor 3 2 4
MIRT490217 SLC37A2 solute carrier family 37 member 2 2 4
MIRT494736 ARHGAP1 Rho GTPase activating protein 1 2 6
MIRT495463 PNMAL2 paraneoplastic Ma antigen family member 8B 2 2
MIRT495495 VTI1B vesicle transport through interaction with t-SNAREs 1B 2 2
MIRT495730 AGO1 argonaute 1, RISC catalytic component 2 2
MIRT495776 ZNF546 zinc finger protein 546 2 2
MIRT495808 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT495828 TMEM151A transmembrane protein 151A 2 2
MIRT496080 ATP1B4 ATPase Na+/K+ transporting family member beta 4 2 2
MIRT496104 SNX17 sorting nexin 17 2 2
MIRT496141 RBL1 RB transcriptional corepressor like 1 2 2
MIRT496183 TRIM73 tripartite motif containing 73 2 2
MIRT496237 TRIM74 tripartite motif containing 74 2 2
MIRT496266 SHROOM2 shroom family member 2 2 2
MIRT496281 SLC2A13 solute carrier family 2 member 13 2 2
MIRT496293 BAZ2A bromodomain adjacent to zinc finger domain 2A 2 2
MIRT496501 MAST3 microtubule associated serine/threonine kinase 3 2 2
MIRT496546 EBI3 Epstein-Barr virus induced 3 2 2
MIRT496929 DPYSL5 dihydropyrimidinase like 5 2 2
MIRT499164 EYA3 EYA transcriptional coactivator and phosphatase 3 2 2
MIRT499323 IGSF9 immunoglobulin superfamily member 9 2 2
MIRT500561 XBP1P1 X-box binding protein 1 pseudogene 1 2 8
MIRT502505 EVI5 ecotropic viral integration site 5 2 2
MIRT503042 CAMSAP2 calmodulin regulated spectrin associated protein family member 2 2 2
MIRT503530 ATG12 autophagy related 12 2 2
MIRT507274 FERMT2 fermitin family member 2 2 2
MIRT510472 ZDHHC18 zinc finger DHHC-type containing 18 2 2
MIRT510696 SRM spermidine synthase 2 6
MIRT512281 ARHGDIA Rho GDP dissociation inhibitor alpha 2 6
MIRT512638 CPEB3 cytoplasmic polyadenylation element binding protein 3 2 4
MIRT512727 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT512945 MAP3K7 mitogen-activated protein kinase kinase kinase 7 2 4
MIRT513150 CSDC2 cold shock domain containing C2 2 2
MIRT514488 SLPI secretory leukocyte peptidase inhibitor 2 4
MIRT516456 IFNGR1 interferon gamma receptor 1 2 6
MIRT517420 BMP8A bone morphogenetic protein 8a 2 2
MIRT527519 FAM172A family with sequence similarity 172 member A 2 2
MIRT535051 PQLC1 PQ loop repeat containing 1 2 2
MIRT542619 XIAP X-linked inhibitor of apoptosis 2 2
MIRT546544 SATB2 SATB homeobox 2 2 2
MIRT548046 GOLIM4 golgi integral membrane protein 4 2 2
MIRT550432 ORC4 origin recognition complex subunit 4 2 2
MIRT551595 HDGFRP2 HDGF like 2 2 2
MIRT551709 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT555848 PAPD7 poly(A) RNA polymerase D7, non-canonical 2 4
MIRT556805 KIAA1958 KIAA1958 2 2
MIRT557554 GOSR1 golgi SNAP receptor complex member 1 2 2
MIRT559322 ATXN1 ataxin 1 2 2
MIRT559742 ACOX1 acyl-CoA oxidase 1 2 2
MIRT559972 PARP2 poly(ADP-ribose) polymerase 2 2 2
MIRT560797 EPM2AIP1 EPM2A interacting protein 1 2 2
MIRT562837 GCFC2 GC-rich sequence DNA-binding factor 2 2 2
MIRT564055 NDUFA7 NADH:ubiquinone oxidoreductase subunit A7 2 2
MIRT564250 LLPH LLP homolog, long-term synaptic facilitation 2 2
MIRT566806 MB21D2 Mab-21 domain containing 2 2 2
MIRT570094 SCN2B sodium voltage-gated channel beta subunit 2 2 2
MIRT575233 Fut1 fucosyltransferase 1 2 2
MIRT576653 Mill2 MHC I like leukocyte 2 1 1
MIRT609259 XRCC3 X-ray repair cross complementing 3 2 2
MIRT611202 TMEM105 transmembrane protein 105 2 2
MIRT613405 DNAH17 dynein axonemal heavy chain 17 2 2
MIRT614314 C9orf62 chromosome 9 open reading frame 62 2 2
MIRT614378 AMZ1 archaelysin family metallopeptidase 1 2 2
MIRT614483 FRMPD3 FERM and PDZ domain containing 3 2 2
MIRT614603 IRF2BPL interferon regulatory factor 2 binding protein like 2 2
MIRT618743 KIF1B kinesin family member 1B 2 2
MIRT628410 BSN bassoon presynaptic cytomatrix protein 2 2
MIRT630340 PAQR5 progestin and adipoQ receptor family member 5 2 2
MIRT632737 MLLT6 MLLT6, PHD finger containing 2 2
MIRT633734 BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 2 2
MIRT636056 ZSCAN29 zinc finger and SCAN domain containing 29 2 4
MIRT638836 CRTAP cartilage associated protein 2 2
MIRT643909 TCEB2 elongin B 2 2
MIRT649313 IGSF6 immunoglobulin superfamily member 6 2 2
MIRT655027 PLA2G16 phospholipase A2 group XVI 2 4
MIRT661320 CPM carboxypeptidase M 2 2
MIRT662143 ZC3H8 zinc finger CCCH-type containing 8 2 2
MIRT663248 MPHOSPH8 M-phase phosphoprotein 8 2 4
MIRT664303 HINT1 histidine triad nucleotide binding protein 1 2 2
MIRT665042 SLC35E2 solute carrier family 35 member E2 2 2
MIRT667992 HECTD3 HECT domain E3 ubiquitin protein ligase 3 2 2
MIRT668465 FAM208A family with sequence similarity 208 member A 2 2
MIRT671593 KLHL21 kelch like family member 21 2 2
MIRT675366 KLHL26 kelch like family member 26 2 2
MIRT677448 PDE11A phosphodiesterase 11A 2 2
MIRT680620 KIAA0391 KIAA0391 2 2
MIRT680654 KIAA1456 KIAA1456 2 2
MIRT680721 PCCB propionyl-CoA carboxylase beta subunit 2 2
MIRT680735 PRICKLE1 prickle planar cell polarity protein 1 2 2
MIRT680890 MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1 like 2 2
MIRT680911 SCN3B sodium voltage-gated channel beta subunit 3 2 2
MIRT681019 AAED1 AhpC/TSA antioxidant enzyme domain containing 1 2 2
MIRT681180 IBA57 IBA57 homolog, iron-sulfur cluster assembly 2 2
MIRT681252 ZNF383 zinc finger protein 383 2 2
MIRT681379 VHLL VHL like 2 2
MIRT681454 CIITA class II major histocompatibility complex transactivator 2 2
MIRT681628 F2RL2 coagulation factor II thrombin receptor like 2 2 2
MIRT681646 SCRG1 stimulator of chondrogenesis 1 2 2
MIRT681680 COX18 COX18, cytochrome c oxidase assembly factor 2 2
MIRT681928 KAT7 lysine acetyltransferase 7 2 2
MIRT681969 TFCP2 transcription factor CP2 2 2
MIRT681993 HRH4 histamine receptor H4 2 2
MIRT682012 ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B) 2 2
MIRT682018 GNAT1 G protein subunit alpha transducin 1 2 2
MIRT682052 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT682128 THBS1 thrombospondin 1 2 2
MIRT682159 SMS spermine synthase 2 2
MIRT682204 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT682430 NRXN3 neurexin 3 2 2
MIRT682470 MCUR1 mitochondrial calcium uniporter regulator 1 2 2
MIRT682497 KATNAL1 katanin catalytic subunit A1 like 1 2 2
MIRT682556 EXOSC2 exosome component 2 2 2
MIRT683775 CPE carboxypeptidase E 2 2
MIRT686015 NEK4 NIMA related kinase 4 2 2
MIRT686079 PTK6 protein tyrosine kinase 6 2 2
MIRT687341 OSBPL2 oxysterol binding protein like 2 2 2
MIRT687763 KIAA1328 KIAA1328 2 2
MIRT688090 GLUL glutamate-ammonia ligase 2 2
MIRT688794 CCNB1 cyclin B1 2 2
MIRT688963 ATXN3 ataxin 3 2 2
MIRT689388 ZNF850 zinc finger protein 850 2 2
MIRT689415 UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 2 2
MIRT689502 SCARF1 scavenger receptor class F member 1 2 2
MIRT690555 GNG4 G protein subunit gamma 4 2 2
MIRT690677 RPF2 ribosome production factor 2 homolog 2 2
MIRT691144 HJURP Holliday junction recognition protein 2 2
MIRT691200 NIF3L1 NGG1 interacting factor 3 like 1 2 2
MIRT691561 OR51E2 olfactory receptor family 51 subfamily E member 2 2 2
MIRT691984 PLCXD1 phosphatidylinositol specific phospholipase C X domain containing 1 2 2
MIRT693580 PIGR polymeric immunoglobulin receptor 2 2
MIRT693804 RHOG ras homolog family member G 2 2
MIRT694026 PPIL4 peptidylprolyl isomerase like 4 2 2
MIRT694244 ZNF749 zinc finger protein 749 2 2
MIRT694712 CD300LG CD300 molecule like family member g 2 2
MIRT695696 ATP6V0D2 ATPase H+ transporting V0 subunit d2 2 2
MIRT695744 ZNF117 zinc finger protein 117 2 2
MIRT696388 SLC27A1 solute carrier family 27 member 1 2 2
MIRT696665 AGXT2 alanine--glyoxylate aminotransferase 2 2 2
MIRT697003 CCDC80 coiled-coil domain containing 80 2 2
MIRT697016 HAUS5 HAUS augmin like complex subunit 5 2 2
MIRT697140 B4GALT7 beta-1,4-galactosyltransferase 7 2 2
MIRT698238 TMEM216 transmembrane protein 216 2 2
MIRT699506 SKIL SKI like proto-oncogene 2 2
MIRT700423 QDPR quinoid dihydropteridine reductase 2 2
MIRT700529 PTPLB 3-hydroxyacyl-CoA dehydratase 2 1 1
MIRT700729 PNO1 partner of NOB1 homolog 2 2
MIRT702838 HOOK3 hook microtubule tethering protein 3 2 2
MIRT703452 FYTTD1 forty-two-three domain containing 1 2 2
MIRT706157 ZNF674 zinc finger protein 674 2 2
MIRT706183 ZNF716 zinc finger protein 716 2 2
MIRT706484 SNX27 sorting nexin family member 27 2 2
MIRT714457 PTDSS2 phosphatidylserine synthase 2 2 2
MIRT720295 DLGAP3 DLG associated protein 3 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-6511a-5p Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-6511a-5p Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-miR-6511a-5p Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-6511a-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (MGC-803)

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