miRTarBase - #MIRT063068


—
pre-miRNA Information
pre-miRNA hsa-mir-520e   
Genomic Coordinates chr19: 53675711 - 53675797
Description Homo sapiens miR-520e stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-520e
Sequence 54| AAAGUGCUUCCUUUUUGAGGG |74
Evidence Experimental
Experiments Array-cloned
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol ULK1   
Synonyms ATG1, ATG1A, UNC51, Unc51.1, hATG1
Description unc-51 like autophagy activating kinase 1
Transcript NM_003565   
Expression
Putative miRNA Targets on ULK1
3'UTR of ULK1
(miRNA target sites are highlighted)		 
>ULK1|NM_003565|3'UTR
   1 CCTTTCTGGCCTGGCTGGGCCCCCCGTCCTGCCGAGCCCTGCAGAGTGGGCTCTGTGTGCTGGCTGGACTCCTCGGGACA
  81 AGCCCATGGCGCTGATCGCTGGTGCTGAGCCCTGCCCTGGGCCCCACGGACAGTCAGCCTGCCGGCCTCCCTGCAGCTCA
 161 CGGGGCAGAACCAGCACATCTGGAGCCACACAGCTTGGGGGGTGTCTCCCATCTTTTACAGGTGGGGATCACAGAATTTC
 241 TGCCCCTCCAGCTGCCTGGCTCAGCAGGCGTGGGTGCCACCACCCTCTAGCCCCAGGGCAGCCCCGGAGGACAGGCAAGG
 321 GCCTGAGACCACTGCCGACTCAAAGCCAAAGCGAGCTCCTGCTTAGGGCAGGTCAGCAGGCACTGTGCCCAGGAAGAGCC
 401 TGCGGCCTCGGCGTCCCCCAGTCTCCAGGAGCCTCTCCCTCCGAGATACCCACCCAGCTTTGTCAATCACCCAAGCACTT
 481 TATGCATATAGAGACAGAACCTGGACCTCACCAGGGACTGCTGGGCAGCGATTCCTGGCAGTGGCCTGGTGTTTGTACAT
 561 ACACATATGCAGACACATGCCAGGGCCCCCCAAGCCCGAGCACCGGACCACGTTGCTGCCCAGGTCTGGACCTCAGCGGG
 641 AGAACTGGCTCCGGGGGGAGTGGGGCCCTGCGCTAGAGGCAGAGGCAGTTCTTTGTTCAAGCGTTCCTCTGGGGACCGGC
 721 AGCAGAGGCACCGTGTTCTCTCAGCCCTGGATACGTCTTGTAATCTTTCACACTTTATTCCTAAAACGTGTCTTATTTTT
 801 ATGCAGCTCATTTTTTCTTTAAAGGAGAAAACTTGTAGGTGTTTAAGAATTGGTTTTGGGAGGGCGAGGACTGGGCCAGG
 881 TTAGAGGCAGATGGCACAGGGGCGTGTGGCGGGCGGGTGAGGCTGCTTTGCACACCTGTGTTGGTGGCTGTCCCCTGCCG
 961 CCCCTCCCTGTGGCAGCAGCAGGACAGGTGTGTGCCCAGCACCCTCCCTACCTGGGCCTGGAAGCAGATGAGGGGAATAC
1041 TTCATGCAAAGAAAAAAGTAACATGTGCAAAAGCTCCCCGTCCAGCTTTGACAGTCAGTTTTGATGTCAGCTCCTCGGCA
1121 GGGTAGGCCTGATGACAGCCCTGTCCCTCCCTGCCTCTGCCTTGCCCAAGGCCACGGAGGGCATCTGCAGAGAGGCCTGC
1201 CTTCCGGATTCCAGGCGGGCATGCCCTGCAAACCCCGCCTGGGCCTCCCTTGGTCTGCCCAGCCCTCGGTTAGCCCTGCC
1281 TGAATCAGTAGATACTTGAACGAGTCCCCAGTCTGCGGGAGGCAGTGGTGGGGCCATGGACCCATGCGGGGGGTTCCAGG
1361 GTCACACGCCACATAACAGACAAAAATACACACACGTGTGTTTTTCTTTGCAATACTTGAAATATTGCCACTGTGCTTGG
1441 ACTTAGAAGAAGAAAATCCCCGTGACTTCTTCCTCATCACCTTGATGGCTTTATTCTCACCTTGTGGGGCATGTTTGTAT
1521 TTATTGCTTCATGGCCGACTGGAATCCTGAGTCCTGGGAAGCTGGCACTGCGGGGATCTTGCCCGGTGTCCTGGTCCTCT
1601 TGCTTCCGTCGCGGCCGCATGTGCGTGTGTCCAAGCAGGTCCTGGGCGCCTCAACTGCTGCCCCTGGTTGAATGTTCTCT
1681 TGATAGTGCTGGACCCTTTGTCTATTTTAAAGCGAATTTTGTGTGATTTCCTGCCCTTTGCGTTATATTGTATAATACCA
1761 ACGTAAGGAAATAAACCTTTGGAATTGTTGGGCTGGTGTCAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gggAGUU-UUUCCUUCGUGAAa 5'
             ||||  |   |||||||| 
Target 5' ttgTCAATCACCCAAGCACTTt 3'
 460 - 481 150.00 -11.50
2 
miRNA  3' ggGAGUUUUUC--CU---UCGUGAAa 5'
            |||| :::|  ||   ||||| | 
Target 5' agCTCACGGGGCAGAACCAGCACATc 3'
 155 - 180 121.00 -9.03
3 
miRNA  3' ggGAGUUUU-UCC-----UUCGUGAaa 5'
            ||:|::: |||     |:|||||  
Target 5' tgCTTAGGGCAGGTCAGCAGGCACTgt 3'
 360 - 386 119.00 -12.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30449113 25 COSMIC
COSN30481036 29 COSMIC
COSN31601342 35 COSMIC
COSN31602108 45 COSMIC
COSN30525145 76 COSMIC
COSN30503686 93 COSMIC
COSN30507271 117 COSMIC
COSN31578956 121 COSMIC
COSN511432 128 COSMIC
COSN7318417 129 COSMIC
COSN31611043 156 COSMIC
COSN24229403 163 COSMIC
COSN14657020 438 COSMIC
COSN31583051 444 COSMIC
COSN31573102 527 COSMIC
COSN19672378 629 COSMIC
COSN31784525 673 COSMIC
COSN26729787 761 COSMIC
COSN32055739 961 COSMIC
COSN28819062 1184 COSMIC
COSN10101593 1286 COSMIC
COSN17315790 1308 COSMIC
COSN31603503 1354 COSMIC
COSN2460794 1409 COSMIC
COSN7611710 1532 COSMIC
COSN21948458 1609 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1481546923 2 dbSNP
rs771514895 3 dbSNP
rs772729317 4 dbSNP
rs746934452 6 dbSNP
rs1038836368 10 dbSNP
rs770836895 11 dbSNP
rs1309708928 12 dbSNP
rs1208477856 16 dbSNP
rs776475197 18 dbSNP
rs1160069028 20 dbSNP
rs750927017 20 dbSNP
rs1461986189 21 dbSNP
rs759311027 22 dbSNP
rs1246325895 23 dbSNP
rs1457673230 23 dbSNP
rs1305341405 24 dbSNP
rs765491965 25 dbSNP
rs560655718 26 dbSNP
rs764101240 27 dbSNP
rs759019938 28 dbSNP
rs532885288 30 dbSNP
rs1405037692 32 dbSNP
rs1470052451 33 dbSNP
rs768128866 34 dbSNP
rs750871373 35 dbSNP
rs756520303 41 dbSNP
rs1270224153 43 dbSNP
rs1338541259 46 dbSNP
rs370168416 46 dbSNP
rs199539761 47 dbSNP
rs1217946026 49 dbSNP
rs377292381 51 dbSNP
rs1324699484 52 dbSNP
rs569199199 54 dbSNP
rs886137847 58 dbSNP
rs1004505514 69 dbSNP
rs1016286463 75 dbSNP
rs139770549 76 dbSNP
rs1003309287 80 dbSNP
rs548396528 91 dbSNP
rs149798813 92 dbSNP
rs1023111369 98 dbSNP
rs1278309699 99 dbSNP
rs533755093 111 dbSNP
rs553584916 114 dbSNP
rs978807401 128 dbSNP
rs576604770 129 dbSNP
rs1028230905 132 dbSNP
rs934672469 140 dbSNP
rs1445596160 141 dbSNP
rs539396975 142 dbSNP
rs1005507083 144 dbSNP
rs1222235959 145 dbSNP
rs1401518807 160 dbSNP
rs1014886709 162 dbSNP
rs143997642 162 dbSNP
rs575954416 163 dbSNP
rs976155065 172 dbSNP
rs922043858 173 dbSNP
rs1472066497 186 dbSNP
rs1237275599 188 dbSNP
rs911809976 194 dbSNP
rs953571422 202 dbSNP
rs944615674 205 dbSNP
rs1215325536 209 dbSNP
rs1039280732 212 dbSNP
rs1359503173 213 dbSNP
rs183487764 220 dbSNP
rs1226559430 225 dbSNP
rs1355482929 226 dbSNP
rs1405316077 227 dbSNP
rs1324216660 228 dbSNP
rs1432621583 231 dbSNP
rs1342664331 235 dbSNP
rs1296546081 249 dbSNP
rs561786668 250 dbSNP
rs915054680 252 dbSNP
rs79733461 257 dbSNP
rs1404098029 261 dbSNP
rs1413703028 263 dbSNP
rs541108396 266 dbSNP
rs1422603010 270 dbSNP
rs749490373 271 dbSNP
rs1370890824 281 dbSNP
rs1444087667 282 dbSNP
rs1490397959 283 dbSNP
rs1270429003 285 dbSNP
rs923621870 301 dbSNP
rs1451023695 306 dbSNP
rs78957317 307 dbSNP
rs1216149051 316 dbSNP
rs369905322 320 dbSNP
rs552607135 321 dbSNP
rs1014469686 322 dbSNP
rs1023564225 323 dbSNP
rs970248765 327 dbSNP
rs894929272 328 dbSNP
rs1205906696 331 dbSNP
rs1266475996 337 dbSNP
rs1467611377 340 dbSNP
rs1398586836 343 dbSNP
rs1446596489 347 dbSNP
rs1194015417 348 dbSNP
rs777154532 353 dbSNP
rs563151092 354 dbSNP
rs1012407497 360 dbSNP
rs1197178894 362 dbSNP
rs770830296 367 dbSNP
rs1480644846 368 dbSNP
rs1178278391 369 dbSNP
rs7311029 370 dbSNP
rs548529062 373 dbSNP
rs1399735016 375 dbSNP
rs956079017 377 dbSNP
rs769603905 382 dbSNP
rs1049232069 384 dbSNP
rs1435021313 388 dbSNP
rs989236215 392 dbSNP
rs911856039 394 dbSNP
rs775213513 400 dbSNP
rs1225766871 403 dbSNP
rs763094377 404 dbSNP
rs762638363 405 dbSNP
rs1217588785 408 dbSNP
rs1303653341 408 dbSNP
rs770474167 410 dbSNP
rs748055865 411 dbSNP
rs930504041 413 dbSNP
rs761933743 414 dbSNP
rs768182210 416 dbSNP
rs1331175600 419 dbSNP
rs1048869521 422 dbSNP
rs1360576770 424 dbSNP
rs997501494 426 dbSNP
rs1361817743 434 dbSNP
rs1413503937 435 dbSNP
rs1469370114 436 dbSNP
rs1158773244 442 dbSNP
rs1029398568 443 dbSNP
rs751003246 444 dbSNP
rs1301944323 447 dbSNP
rs1366756272 448 dbSNP
rs1484095802 448 dbSNP
rs766865180 449 dbSNP
rs1306604312 451 dbSNP
rs1335537421 453 dbSNP
rs1240139922 454 dbSNP
rs772053910 455 dbSNP
rs953525240 456 dbSNP
rs907646145 459 dbSNP
rs568097921 463 dbSNP
rs940430270 465 dbSNP
rs1056536653 467 dbSNP
rs1022134827 475 dbSNP
rs968265224 476 dbSNP
rs534054630 477 dbSNP
rs1245371574 479 dbSNP
rs896119376 484 dbSNP
rs1012319181 487 dbSNP
rs777259960 491 dbSNP
rs148669024 502 dbSNP
rs1490505279 504 dbSNP
rs1381825226 506 dbSNP
rs746471386 507 dbSNP
rs758055266 510 dbSNP
rs1437031207 512 dbSNP
rs906100291 513 dbSNP
rs1000378314 519 dbSNP
rs991863603 521 dbSNP
rs777466990 522 dbSNP
rs142207215 530 dbSNP
rs751078104 531 dbSNP
rs947838282 535 dbSNP
rs1049260340 538 dbSNP
rs887968915 540 dbSNP
rs756728260 542 dbSNP
rs956321751 543 dbSNP
rs1010285889 544 dbSNP
rs1427179026 545 dbSNP
rs1386279355 546 dbSNP
rs940885688 547 dbSNP
rs1036475822 556 dbSNP
rs780636514 560 dbSNP
rs902136105 562 dbSNP
rs1019437340 563 dbSNP
rs1429556421 564 dbSNP
rs1323955118 569 dbSNP
rs1228092129 571 dbSNP
rs1362280329 572 dbSNP
rs966108553 575 dbSNP
rs1356850404 586 dbSNP
rs1397706858 588 dbSNP
rs997718829 589 dbSNP
rs1331239761 590 dbSNP
rs745824432 595 dbSNP
rs780264949 595 dbSNP
rs1338977209 598 dbSNP
rs759531710 599 dbSNP
rs770372394 605 dbSNP
rs889079771 606 dbSNP
rs539576211 612 dbSNP
rs1249548610 613 dbSNP
rs1210499642 616 dbSNP
rs556184682 620 dbSNP
rs1011681942 628 dbSNP
rs1196181332 631 dbSNP
rs1316845759 632 dbSNP
rs1274828475 635 dbSNP
rs1022153251 636 dbSNP
rs569902950 638 dbSNP
rs535119942 639 dbSNP
rs1280442131 640 dbSNP
rs1216429845 641 dbSNP
rs767371916 646 dbSNP
rs749098899 648 dbSNP
rs1190352184 649 dbSNP
rs747147700 650 dbSNP
rs1462927032 651 dbSNP
rs768812850 652 dbSNP
rs1387998274 653 dbSNP
rs907674271 653 dbSNP
rs759152346 654 dbSNP
rs541333651 656 dbSNP
rs1056251985 659 dbSNP
rs1462388128 660 dbSNP
rs1385175064 665 dbSNP
rs917657227 666 dbSNP
rs1380635792 667 dbSNP
rs1294883393 668 dbSNP
rs947774904 670 dbSNP
rs769123971 672 dbSNP
rs1228022318 673 dbSNP
rs189386684 679 dbSNP
rs992043781 680 dbSNP
rs1434946706 681 dbSNP
rs1185620415 685 dbSNP
rs200791504 690 dbSNP
rs774918603 695 dbSNP
rs1321128085 699 dbSNP
rs1202730857 701 dbSNP
rs947686557 702 dbSNP
rs572069501 703 dbSNP
rs773369303 704 dbSNP
rs181994403 707 dbSNP
rs891994888 708 dbSNP
rs1256202263 713 dbSNP
rs1429698823 715 dbSNP
rs1195937750 717 dbSNP
rs1010816948 718 dbSNP
rs766990246 719 dbSNP
rs1177553258 724 dbSNP
rs1299921534 729 dbSNP
rs1408600654 730 dbSNP
rs1019049919 733 dbSNP
rs754211447 734 dbSNP
rs1329114241 736 dbSNP
rs1385754785 739 dbSNP
rs1399888338 741 dbSNP
rs557848943 746 dbSNP
rs908984353 751 dbSNP
rs1467732949 754 dbSNP
rs762407172 755 dbSNP
rs146750687 756 dbSNP
rs1343525407 757 dbSNP
rs1222699905 759 dbSNP
rs901979012 760 dbSNP
rs7138581 761 dbSNP
rs1313632409 770 dbSNP
rs566384475 773 dbSNP
rs1259693569 774 dbSNP
rs961945099 777 dbSNP
rs1051086352 778 dbSNP
rs1215117902 779 dbSNP
rs377506186 788 dbSNP
rs1267417232 789 dbSNP
rs1129619 792 dbSNP
rs1355824539 797 dbSNP
rs1200660207 802 dbSNP
rs889358690 803 dbSNP
rs992384233 806 dbSNP
rs1263986008 809 dbSNP
rs564479142 810 dbSNP
rs1158635275 813 dbSNP
rs879705574 820 dbSNP
rs1420361330 825 dbSNP
rs1455412349 828 dbSNP
rs1301321710 829 dbSNP
rs903309437 836 dbSNP
rs1404227469 838 dbSNP
rs1303611075 856 dbSNP
rs947770846 859 dbSNP
rs1190044049 861 dbSNP
rs1221799850 866 dbSNP
rs1305860723 867 dbSNP
rs1440390819 875 dbSNP
rs1427531233 887 dbSNP
rs532066108 896 dbSNP
rs1030847772 898 dbSNP
rs980436054 900 dbSNP
rs1013523388 903 dbSNP
rs1023996204 904 dbSNP
rs924906825 905 dbSNP
rs542094526 910 dbSNP
rs1476896177 911 dbSNP
rs561792266 912 dbSNP
rs1318297315 914 dbSNP
rs908879571 915 dbSNP
rs533854106 916 dbSNP
rs547494938 918 dbSNP
rs1040916115 932 dbSNP
rs1362551513 934 dbSNP
rs1296343747 936 dbSNP
rs1400705816 939 dbSNP
rs1415141984 941 dbSNP
rs901945850 945 dbSNP
rs1222481285 959 dbSNP
rs760757302 960 dbSNP
rs867327365 961 dbSNP
rs1215258341 964 dbSNP
rs1452170090 965 dbSNP
rs1291910368 978 dbSNP
rs996179427 984 dbSNP
rs1355420123 986 dbSNP
rs766396780 989 dbSNP
rs1050605914 990 dbSNP
rs1219484434 999 dbSNP
rs887813124 1001 dbSNP
rs1342605942 1004 dbSNP
rs1276448732 1007 dbSNP
rs1352278647 1009 dbSNP
rs1202821603 1010 dbSNP
rs570561774 1011 dbSNP
rs1326145385 1015 dbSNP
rs1404042852 1016 dbSNP
rs1394224886 1017 dbSNP
rs1283557459 1018 dbSNP
rs1171755557 1020 dbSNP
rs1490488716 1024 dbSNP
rs1006176433 1028 dbSNP
rs760338308 1031 dbSNP
rs1421010034 1038 dbSNP
rs1185480166 1039 dbSNP
rs1478052442 1045 dbSNP
rs1247906481 1048 dbSNP
rs1450894464 1052 dbSNP
rs962239793 1052 dbSNP
rs1258544229 1054 dbSNP
rs992022181 1059 dbSNP
rs1025189859 1062 dbSNP
rs1320334416 1063 dbSNP
rs530591574 1063 dbSNP
rs1214160194 1064 dbSNP
rs1368420338 1065 dbSNP
rs754057493 1066 dbSNP
rs969134340 1067 dbSNP
rs980548861 1074 dbSNP
rs1434954659 1077 dbSNP
rs1370906019 1080 dbSNP
rs187098582 1081 dbSNP
rs549912121 1086 dbSNP
rs1397728086 1093 dbSNP
rs3088051 1103 dbSNP
rs1414635291 1104 dbSNP
rs1170290663 1111 dbSNP
rs535789829 1117 dbSNP
rs1453780534 1118 dbSNP
rs1238686187 1121 dbSNP
rs555691748 1122 dbSNP
rs946268988 1131 dbSNP
rs1040552523 1146 dbSNP
rs1204106753 1148 dbSNP
rs1312926035 1150 dbSNP
rs1280909148 1160 dbSNP
rs1415177838 1169 dbSNP
rs901977025 1171 dbSNP
rs1427035188 1174 dbSNP
rs1301717631 1176 dbSNP
rs1801866 1177 dbSNP
rs1013864982 1180 dbSNP
rs1448384539 1182 dbSNP
rs9481 1184 dbSNP
rs1173398952 1188 dbSNP
rs1433524717 1192 dbSNP
rs1329174604 1194 dbSNP
rs1337158793 1195 dbSNP
rs1437683945 1196 dbSNP
rs887845827 1206 dbSNP
rs1006207642 1207 dbSNP
rs1278384822 1209 dbSNP
rs534554456 1212 dbSNP
rs538004170 1217 dbSNP
rs1239409495 1218 dbSNP
rs1006095511 1219 dbSNP
rs1485405999 1221 dbSNP
rs1248026784 1222 dbSNP
rs1242972512 1232 dbSNP
rs1352064741 1233 dbSNP
rs897743265 1234 dbSNP
rs1013886179 1237 dbSNP
rs758193044 1238 dbSNP
rs961658555 1241 dbSNP
rs969247730 1263 dbSNP
rs1002018025 1266 dbSNP
rs777639920 1268 dbSNP
rs1413735038 1269 dbSNP
rs4964914 1270 dbSNP
rs1253001959 1277 dbSNP
rs1436237352 1290 dbSNP
rs1344521517 1295 dbSNP
rs140324821 1298 dbSNP
rs189933492 1301 dbSNP
rs913520811 1302 dbSNP
rs967665767 1303 dbSNP
rs1264006661 1310 dbSNP
rs976774771 1317 dbSNP
rs1485204637 1318 dbSNP
rs1260613144 1323 dbSNP
rs923546005 1324 dbSNP
rs1222894920 1325 dbSNP
rs910684044 1326 dbSNP
rs1291757190 1328 dbSNP
rs1232306145 1329 dbSNP
rs1340737661 1333 dbSNP
rs932176489 1337 dbSNP
rs1050541630 1345 dbSNP
rs1384216181 1346 dbSNP
rs909318336 1348 dbSNP
rs114528807 1349 dbSNP
rs1163861479 1351 dbSNP
rs1057141372 1361 dbSNP
rs1424575927 1363 dbSNP
rs1195981229 1364 dbSNP
rs1426844906 1366 dbSNP
rs139446989 1368 dbSNP
rs1045301026 1374 dbSNP
rs878944991 1376 dbSNP
rs1327636289 1388 dbSNP
rs1382820096 1389 dbSNP
rs1318215875 1391 dbSNP
rs181576786 1392 dbSNP
rs904991306 1395 dbSNP
rs1325374872 1396 dbSNP
rs760705903 1396 dbSNP
rs1013583645 1397 dbSNP
rs1016110640 1398 dbSNP
rs1325028511 1399 dbSNP
rs897735654 1413 dbSNP
rs1358630534 1417 dbSNP
rs1046765991 1418 dbSNP
rs905095474 1426 dbSNP
rs1002049269 1428 dbSNP
rs1372581799 1431 dbSNP
rs1176871823 1432 dbSNP
rs1435481859 1433 dbSNP
rs1251658826 1440 dbSNP
rs1193448666 1444 dbSNP
rs1252783626 1445 dbSNP
rs993158749 1445 dbSNP
rs1337734777 1447 dbSNP
rs1029952284 1452 dbSNP
rs1256147677 1454 dbSNP
rs1234770706 1456 dbSNP
rs1032155311 1461 dbSNP
rs954617742 1462 dbSNP
rs1378849862 1463 dbSNP
rs143984453 1463 dbSNP
rs1462743499 1466 dbSNP
rs745525009 1468 dbSNP
rs769641698 1469 dbSNP
rs1303549427 1470 dbSNP
rs1429566131 1473 dbSNP
rs978908642 1476 dbSNP
rs1173587826 1477 dbSNP
rs924884214 1480 dbSNP
rs1382564120 1484 dbSNP
rs934890221 1488 dbSNP
rs965457074 1493 dbSNP
rs1460169089 1496 dbSNP
rs1256381919 1502 dbSNP
rs1201775693 1503 dbSNP
rs1484414940 1511 dbSNP
rs976427068 1514 dbSNP
rs923553735 1517 dbSNP
rs1278913412 1521 dbSNP
rs953602422 1531 dbSNP
rs775289191 1533 dbSNP
rs1169576043 1534 dbSNP
rs917215058 1537 dbSNP
rs1238033453 1538 dbSNP
rs948823893 1540 dbSNP
rs1406310651 1553 dbSNP
rs1470705317 1554 dbSNP
rs1334056327 1559 dbSNP
rs909350827 1568 dbSNP
rs1381955016 1571 dbSNP
rs1044457635 1572 dbSNP
rs905043224 1573 dbSNP
rs942203575 1574 dbSNP
rs1420910229 1579 dbSNP
rs1297488967 1585 dbSNP
rs1157245071 1586 dbSNP
rs1469972482 1587 dbSNP
rs1369361156 1591 dbSNP
rs1189201704 1598 dbSNP
rs1473981127 1601 dbSNP
rs1324518747 1604 dbSNP
rs941896304 1604 dbSNP
rs1226381069 1607 dbSNP
rs527679131 1608 dbSNP
rs556094518 1609 dbSNP
rs564437171 1611 dbSNP
rs1356814063 1612 dbSNP
rs773726216 1613 dbSNP
rs533498984 1614 dbSNP
rs949441281 1617 dbSNP
rs1260228711 1618 dbSNP
rs1046361649 1620 dbSNP
rs1316868781 1621 dbSNP
rs1400571941 1624 dbSNP
rs1428331652 1626 dbSNP
rs1167544969 1642 dbSNP
rs905127917 1644 dbSNP
rs879579056 1645 dbSNP
rs550005694 1648 dbSNP
rs1239814285 1649 dbSNP
rs1192401231 1650 dbSNP
rs1007742078 1651 dbSNP
rs1291850413 1656 dbSNP
rs1211580901 1659 dbSNP
rs577820365 1664 dbSNP
rs1333031567 1670 dbSNP
rs1173677323 1671 dbSNP
rs1358026410 1675 dbSNP
rs538601334 1678 dbSNP
rs1017379357 1680 dbSNP
rs968861060 1682 dbSNP
rs1453829181 1689 dbSNP
rs1332164379 1692 dbSNP
rs1328403167 1696 dbSNP
rs566070706 1697 dbSNP
rs1290604319 1700 dbSNP
rs115106597 1705 dbSNP
rs114043153 1714 dbSNP
rs1283620107 1715 dbSNP
rs185681394 1718 dbSNP
rs1221869789 1726 dbSNP
rs1282750155 1729 dbSNP
rs900908760 1734 dbSNP
rs1191561201 1735 dbSNP
rs1241229347 1736 dbSNP
rs998273851 1742 dbSNP
rs761122749 1743 dbSNP
rs565952084 1747 dbSNP
rs917251299 1748 dbSNP
rs534617021 1751 dbSNP
rs1214036746 1752 dbSNP
rs986379346 1753 dbSNP
rs551432590 1754 dbSNP
rs1016467817 1759 dbSNP
rs963901713 1763 dbSNP
rs753922444 1764 dbSNP
rs1037501555 1767 dbSNP
rs919347274 1777 dbSNP
rs571134640 1786 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293
Disease 8408.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "HITS-CLIP data was present in GSM714642. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714642
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000321867.4 | 3UTR | CUUUGUCAAUCACCCAAGCACUUUAUGCAUAUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000321867.4 | 3UTR | CCCAGCUUUGUCAAUCACCCAAGCACUUUAUGCAUAUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000321867.4 | 3UTR | UGUCAAUCACCCAAGCACUUUAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE42095 Differentiated embryonic stem cells -0.533 4.4e-3 -0.299 8.3e-2 23 Click to see details
GSE26953 Aortic valvular endothelial cells -0.497 6.7e-3 -0.450 1.4e-2 24 Click to see details
GSE28260 Renal cortex and medulla 0.467 5.4e-2 0.330 1.4e-1 13 Click to see details
GSE28544 Breast cancer 0.28 9.3e-2 0.498 6.6e-3 24 Click to see details
GSE15076 Monocyte-derived dendritic cells -0.5 1.0e-1 -0.339 2.1e-1 8 Click to see details
GSE27834 Pluripotent stem cells -0.295 1.3e-1 -0.206 2.2e-1 16 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.22 1.5e-1 -0.235 1.3e-1 25 Click to see details
GSE17498 Multiple myeloma -0.136 2.0e-1 -0.049 3.8e-1 40 Click to see details
GSE19350 CNS germ cell tumors 0.201 2.7e-1 0.451 7.1e-2 12 Click to see details
GSE21687 Ependynoma primary tumors -0.076 2.8e-1 -0.023 4.3e-1 64 Click to see details
GSE38226 Liver fibrosis 0.129 2.9e-1 0.242 1.5e-1 21 Click to see details
GSE17306 Multiple myeloma 0.053 3.6e-1 0.151 1.5e-1 49 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis -0.051 4.2e-1 0.195 2.1e-1 20 Click to see details
GSE32688 Pancreatic cancer -0.014 4.7e-1 0.084 3.2e-1 32 Click to see details
GSE35602 Colorectal cancer stromal tissue -0.009 4.8e-1 0.108 3.0e-1 25 Click to see details
GSE35602 Colorectal cancer stromal tissue -0.009 4.8e-1 0.108 3.0e-1 25 Click to see details
GSE14794 Lymphoblastoid cells 0 5.0e-1 -0.035 3.7e-1 90 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
0 5.0e-1 -0.035 3.7e-1 90 Click to see details
0 5.0e-1 -0.035 3.7e-1 90 Click to see details
0 5.0e-1 -0.035 3.7e-1 90 Click to see details
0 5.0e-1 -0.035 3.7e-1 90 Click to see details
423 hsa-miR-520e Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT006513 CD46 CD46 molecule 4 1
MIRT007338 PFKP phosphofructokinase, platelet 5 9
MIRT052929 MAP3K14 mitogen-activated protein kinase kinase kinase 14 3 1
MIRT052966 MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 3 1
MIRT057396 TNKS2 tankyrase 2 2 2
MIRT061195 MED17 mediator complex subunit 17 2 2
MIRT061366 WEE1 WEE1 G2 checkpoint kinase 2 2
MIRT063068 ULK1 unc-51 like autophagy activating kinase 1 2 2
MIRT064717 CCND2 cyclin D2 2 2
MIRT065871 GDF11 growth differentiation factor 11 2 2
MIRT066869 TMEM19 transmembrane protein 19 2 2
MIRT067243 FOXJ2 forkhead box J2 2 2
MIRT070853 EIF2S1 eukaryotic translation initiation factor 2 subunit alpha 2 4
MIRT071388 CMPK1 cytidine/uridine monophosphate kinase 1 2 6
MIRT075787 KIAA0513 KIAA0513 2 6
MIRT077844 MINK1 misshapen like kinase 1 2 2
MIRT078824 UNK unkempt family zinc finger 2 2
MIRT079424 FOXK2 forkhead box K2 2 4
MIRT080190 PRKACB protein kinase cAMP-activated catalytic subunit beta 2 2
MIRT083973 RAB22A RAB22A, member RAS oncogene family 2 4
MIRT084955 BACH1 BTB domain and CNC homolog 1 2 2
MIRT093815 KLF3 Kruppel like factor 3 2 2
MIRT093953 SLAIN2 SLAIN motif family member 2 2 2
MIRT108662 ZBTB33 zinc finger and BTB domain containing 33 2 4
MIRT112100 TIMM17A translocase of inner mitochondrial membrane 17A 2 6
MIRT122376 RGMB repulsive guidance molecule family member b 2 4
MIRT124139 GINS4 GINS complex subunit 4 2 4
MIRT130113 TXNIP thioredoxin interacting protein 2 8
MIRT138705 MPP5 membrane palmitoylated protein 5 2 2
MIRT147298 KPNA2 karyopherin subunit alpha 2 2 10
MIRT155916 SIK1 salt inducible kinase 1 2 2
MIRT165910 CREBRF CREB3 regulatory factor 2 2
MIRT173700 PRPF4 pre-mRNA processing factor 4 2 2
MIRT178673 FAM102B family with sequence similarity 102 member B 2 2
MIRT187262 DAZAP2 DAZ associated protein 2 2 10
MIRT199118 ZNF532 zinc finger protein 532 2 2
MIRT199293 SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 2 2
MIRT200934 ZNF264 zinc finger protein 264 2 6
MIRT201032 ZNF805 zinc finger protein 805 2 2
MIRT213215 REST RE1 silencing transcription factor 2 6
MIRT216435 SERF1A small EDRK-rich factor 1A 2 2
MIRT216460 SERF1B small EDRK-rich factor 1B 2 2
MIRT242210 TTC9 tetratricopeptide repeat domain 9 2 4
MIRT242366 IGF1R insulin like growth factor 1 receptor 2 2
MIRT242511 SUZ12 SUZ12 polycomb repressive complex 2 subunit 2 2
MIRT243435 PAK2 p21 (RAC1) activated kinase 2 2 2
MIRT244600 HOOK3 hook microtubule tethering protein 3 2 2
MIRT281001 SPRED1 sprouty related EVH1 domain containing 1 2 2
MIRT302451 CLIP4 CAP-Gly domain containing linker protein family member 4 2 2
MIRT321784 FZD6 frizzled class receptor 6 2 8
MIRT322534 HMBOX1 homeobox containing 1 2 2
MIRT325522 PTPDC1 protein tyrosine phosphatase domain containing 1 2 2
MIRT356941 FEM1C fem-1 homolog C 2 8
MIRT383608 POU2F1 POU class 2 homeobox 1 2 2
MIRT441407 FAM9C family with sequence similarity 9 member C 2 2
MIRT442447 FGF7 fibroblast growth factor 7 2 6
MIRT443074 ABLIM1 actin binding LIM protein 1 2 2
MIRT444420 EMC1 ER membrane protein complex subunit 1 2 2
MIRT446616 HIP1 huntingtin interacting protein 1 2 4
MIRT446807 C5orf30 chromosome 5 open reading frame 30 2 2
MIRT448351 TSR1 TSR1, ribosome maturation factor 2 6
MIRT448743 ITGA2 integrin subunit alpha 2 2 2
MIRT449158 SORCS2 sortilin related VPS10 domain containing receptor 2 2 2
MIRT449251 MICA MHC class I polypeptide-related sequence A 2 2
MIRT450842 IFFO1 intermediate filament family orphan 1 2 2
MIRT450927 CADM2 cell adhesion molecule 2 2 2
MIRT450963 ATAD2 ATPase family, AAA domain containing 2 2 2
MIRT461251 COX10 COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor 2 6
MIRT463601 ZBTB34 zinc finger and BTB domain containing 34 2 2
MIRT467913 SLC22A23 solute carrier family 22 member 23 2 2
MIRT471996 NR1D2 nuclear receptor subfamily 1 group D member 2 2 2
MIRT473611 MARK2 microtubule affinity regulating kinase 2 2 2
MIRT474724 KIF13A kinesin family member 13A 2 6
MIRT476988 FAM73B mitoguardin 2 2 2
MIRT477098 FAM160B1 family with sequence similarity 160 member B1 2 6
MIRT477269 ERGIC2 ERGIC and golgi 2 2 2
MIRT478732 CSNK1A1 casein kinase 1 alpha 1 2 6
MIRT479996 CAPRIN2 caprin family member 2 2 4
MIRT480660 BSCL2 BSCL2, seipin lipid droplet biogenesis associated 2 2
MIRT480836 BLCAP bladder cancer associated protein 2 10
MIRT481755 APH1A aph-1 homolog A, gamma-secretase subunit 2 2
MIRT484830 ZNFX1 zinc finger NFX1-type containing 1 2 2
MIRT484929 ZFYVE26 zinc finger FYVE-type containing 26 2 4
MIRT485347 MYO1D myosin ID 2 2
MIRT485831 ARID4B AT-rich interaction domain 4B 2 4
MIRT486013 LPAR2 lysophosphatidic acid receptor 2 2 2
MIRT493131 MKNK2 MAP kinase interacting serine/threonine kinase 2 2 6
MIRT494082 DUSP2 dual specificity phosphatase 2 2 4
MIRT496048 MORC1 MORC family CW-type zinc finger 1 2 2
MIRT497456 DDR2 discoidin domain receptor tyrosine kinase 2 2 2
MIRT498047 SNX5 sorting nexin 5 2 6
MIRT500881 SUCO SUN domain containing ossification factor 2 4
MIRT501398 RBBP6 RB binding protein 6, ubiquitin ligase 2 8
MIRT503790 ZNF12 zinc finger protein 12 2 6
MIRT504083 C9orf40 chromosome 9 open reading frame 40 2 6
MIRT504278 PARP1 poly(ADP-ribose) polymerase 1 2 6
MIRT505169 YOD1 YOD1 deubiquitinase 2 4
MIRT505212 UBN2 ubinuclein 2 2 8
MIRT505985 RAB11FIP1 RAB11 family interacting protein 1 2 4
MIRT506266 PDPK1 3-phosphoinositide dependent protein kinase 1 2 2
MIRT506975 HNRNPR heterogeneous nuclear ribonucleoprotein R 2 2
MIRT507216 FZD9 frizzled class receptor 9 2 6
MIRT507422 ELK4 ELK4, ETS transcription factor 2 4
MIRT508560 CEP72 centrosomal protein 72 2 4
MIRT508729 ZNF682 zinc finger protein 682 2 4
MIRT508820 GPR155 G protein-coupled receptor 155 2 2
MIRT509114 BMP8B bone morphogenetic protein 8b 2 6
MIRT509421 MCM7 minichromosome maintenance complex component 7 2 6
MIRT509729 EFCAB11 EF-hand calcium binding domain 11 2 4
MIRT510013 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 4
MIRT510210 ZNF317 zinc finger protein 317 2 4
MIRT511304 KIAA1551 KIAA1551 2 2
MIRT511403 IFNAR2 interferon alpha and beta receptor subunit 2 2 6
MIRT511540 HMGB1 high mobility group box 1 2 6
MIRT512023 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT512967 PPP1R14C protein phosphatase 1 regulatory inhibitor subunit 14C 2 4
MIRT513811 NFIB nuclear factor I B 2 2
MIRT514121 SERF2 small EDRK-rich factor 2 2 2
MIRT514304 FXYD5 FXYD domain containing ion transport regulator 5 2 6
MIRT514466 FANCA Fanconi anemia complementation group A 2 2
MIRT515189 CRCP CGRP receptor component 2 2
MIRT515559 TMEM134 transmembrane protein 134 2 2
MIRT515916 MFAP2 microfibril associated protein 2 2 4
MIRT516044 MED18 mediator complex subunit 18 2 2
MIRT516355 GABPB1 GA binding protein transcription factor beta subunit 1 2 2
MIRT516543 MIXL1 Mix paired-like homeobox 2 2
MIRT516783 PTRF caveolae associated protein 1 2 4
MIRT517004 COX19 COX19, cytochrome c oxidase assembly factor 2 2
MIRT517171 SLC28A1 solute carrier family 28 member 1 2 2
MIRT517244 PRIM1 DNA primase subunit 1 2 4
MIRT518301 ZNF514 zinc finger protein 514 2 4
MIRT518452 KIF6 kinesin family member 6 2 2
MIRT518683 KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 2 2
MIRT518788 MED16 mediator complex subunit 16 2 4
MIRT518847 NEK8 NIMA related kinase 8 2 2
MIRT518956 GRK7 G protein-coupled receptor kinase 7 2 2
MIRT519256 PLA2G12A phospholipase A2 group XIIA 2 2
MIRT519416 KCNA7 potassium voltage-gated channel subfamily A member 7 2 4
MIRT519532 TMEM38A transmembrane protein 38A 2 2
MIRT520066 YIPF4 Yip1 domain family member 4 2 2
MIRT520140 WSB1 WD repeat and SOCS box containing 1 2 2
MIRT520294 UBXN2A UBX domain protein 2A 2 2
MIRT520557 TNRC6B trinucleotide repeat containing 6B 2 2
MIRT520818 TAOK1 TAO kinase 1 2 2
MIRT520994 SOCS5 suppressor of cytokine signaling 5 2 2
MIRT521224 SBNO1 strawberry notch homolog 1 2 2
MIRT521533 QSOX1 quiescin sulfhydryl oxidase 1 2 4
MIRT522156 NR2F6 nuclear receptor subfamily 2 group F member 6 2 4
MIRT522206 NR2C2 nuclear receptor subfamily 2 group C member 2 2 6
MIRT522517 MFN1 mitofusin 1 2 2
MIRT522954 IPO9 importin 9 2 2
MIRT523067 HYPK huntingtin interacting protein K 2 2
MIRT523424 GPR157 G protein-coupled receptor 157 2 4
MIRT523555 GIGYF1 GRB10 interacting GYF protein 1 2 6
MIRT523638 FOXK1 forkhead box K1 2 4
MIRT524236 DCTN6 dynactin subunit 6 2 2
MIRT524279 CYCS cytochrome c, somatic 2 2
MIRT524378 CREB1 cAMP responsive element binding protein 1 2 2
MIRT524441 CNKSR3 CNKSR family member 3 2 2
MIRT524758 BCL2L2 BCL2 like 2 2 2
MIRT524967 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT525651 NHSL2 NHS like 2 2 2
MIRT525687 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 2
MIRT526623 NME6 NME/NM23 nucleoside diphosphate kinase 6 2 2
MIRT527536 DLGAP5 DLG associated protein 5 2 4
MIRT529523 ICMT isoprenylcysteine carboxyl methyltransferase 2 2
MIRT529987 TNFAIP8L1 TNF alpha induced protein 8 like 1 2 4
MIRT530134 HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2 2
MIRT530575 ABHD15 abhydrolase domain containing 15 2 2
MIRT530973 EXO5 exonuclease 5 2 4
MIRT531464 TNFRSF10B TNF receptor superfamily member 10b 2 4
MIRT531763 TXK TXK tyrosine kinase 2 4
MIRT532037 FHDC1 FH2 domain containing 1 2 2
MIRT532932 ZNF385A zinc finger protein 385A 2 2
MIRT534519 SAR1B secretion associated Ras related GTPase 1B 2 2
MIRT534615 RNASEH1 ribonuclease H1 2 4
MIRT534773 RASGEF1A RasGEF domain family member 1A 2 2
MIRT535257 PIGA phosphatidylinositol glycan anchor biosynthesis class A 2 4
MIRT535389 PER1 period circadian clock 1 2 2
MIRT536024 MCUR1 mitochondrial calcium uniporter regulator 1 2 2
MIRT536112 MBNL1 muscleblind like splicing regulator 1 2 4
MIRT536172 MAP1B microtubule associated protein 1B 2 3
MIRT536295 LIMA1 LIM domain and actin binding 1 2 2
MIRT536357 LEFTY1 left-right determination factor 1 2 2
MIRT536425 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT536548 KCNJ8 potassium voltage-gated channel subfamily J member 8 2 2
MIRT536616 IRF2 interferon regulatory factor 2 2 2
MIRT536630 INO80D INO80 complex subunit D 2 2
MIRT536868 HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 2 2
MIRT536954 HAS3 hyaluronan synthase 3 2 2
MIRT536981 HABP4 hyaluronan binding protein 4 2 4
MIRT537247 GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 2 2
MIRT537434 FBXL7 F-box and leucine rich repeat protein 7 2 2
MIRT537550 ETNK1 ethanolamine kinase 1 2 2
MIRT537745 ELAVL2 ELAV like RNA binding protein 2 2 2
MIRT537960 DPYSL2 dihydropyrimidinase like 2 2 2
MIRT538003 DPP8 dipeptidyl peptidase 8 2 2
MIRT538258 CUL3 cullin 3 2 4
MIRT538513 CLCN3 chloride voltage-gated channel 3 2 2
MIRT538583 CECR2 CECR2, histone acetyl-lysine reader 2 2
MIRT538647 CCSAP centriole, cilia and spindle associated protein 2 2
MIRT538860 BTG1 BTG anti-proliferation factor 1 2 2
MIRT538911 BRI3BP BRI3 binding protein 2 2
MIRT539011 AVL9 AVL9 cell migration associated 2 2
MIRT539058 ATP6V1C1 ATPase H+ transporting V1 subunit C1 2 4
MIRT539102 ARL10 ADP ribosylation factor like GTPase 10 2 2
MIRT539437 ADAT2 adenosine deaminase, tRNA specific 2 2 2
MIRT540262 FAM89A family with sequence similarity 89 member A 2 2
MIRT540376 MASTL microtubule associated serine/threonine kinase like 2 2
MIRT541293 GLO1 glyoxalase I 2 2
MIRT542129 DIS3L DIS3 like exosome 3'-5' exoribonuclease 2 2
MIRT542255 HSPA4L heat shock protein family A (Hsp70) member 4 like 2 2
MIRT546546 SATB2 SATB homeobox 2 2 2
MIRT547480 MBNL3 muscleblind like splicing regulator 3 2 4
MIRT547639 LCLAT1 lysocardiolipin acyltransferase 1 2 4
MIRT547880 HSPA13 heat shock protein family A (Hsp70) member 13 2 2
MIRT548567 DNAJB14 DnaJ heat shock protein family (Hsp40) member B14 2 2
MIRT550865 SNAP47 synaptosome associated protein 47 2 4
MIRT552161 DAD1 defender against cell death 1 2 2
MIRT552191 F2RL3 F2R like thrombin or trypsin receptor 3 2 2
MIRT553584 TMEM100 transmembrane protein 100 2 2
MIRT553680 TFAP4 transcription factor AP-4 2 4
MIRT554438 SAMD8 sterile alpha motif domain containing 8 2 2
MIRT554496 SAMD12 sterile alpha motif domain containing 12 2 2
MIRT554758 RHOC ras homolog family member C 2 2
MIRT555452 POLR3A RNA polymerase III subunit A 2 2
MIRT556536 LIN52 lin-52 DREAM MuvB core complex component 2 2
MIRT557069 HOXB3 homeobox B3 2 2
MIRT557649 GATA6 GATA binding protein 6 2 2
MIRT560236 KLHL21 kelch like family member 21 2 4
MIRT561335 ZBTB18 zinc finger and BTB domain containing 18 2 2
MIRT566274 PRRG4 proline rich and Gla domain 4 2 2
MIRT567080 KBTBD2 kelch repeat and BTB domain containing 2 2 2
MIRT567939 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT567980 COX6B1 cytochrome c oxidase subunit 6B1 2 2
MIRT568167 CCDC6 coiled-coil domain containing 6 2 2
MIRT571711 RPL17-C18orf32 RPL17-C18orf32 readthrough 2 2
MIRT571762 PSD3 pleckstrin and Sec7 domain containing 3 2 2
MIRT572197 C18orf32 chromosome 18 open reading frame 32 2 2
MIRT572664 AGMAT agmatinase 2 4
MIRT573696 RBM12B RNA binding motif protein 12B 2 2
MIRT574574 NR2F2 nuclear receptor subfamily 2 group F member 2 2 2
MIRT574731 HAUS8 HAUS augmin like complex subunit 8 2 2
MIRT575713 Map1b microtubule-associated protein 1B 2 3
MIRT608736 MYH9 myosin heavy chain 9 2 2
MIRT612599 RANGAP1 Ran GTPase activating protein 1 2 2
MIRT614251 WDR53 WD repeat domain 53 2 4
MIRT615164 SPIB Spi-B transcription factor 2 2
MIRT616160 TCEB1 elongin C 2 2
MIRT616799 FEM1A fem-1 homolog A 2 2
MIRT617866 ESR1 estrogen receptor 1 2 2
MIRT619829 POLM DNA polymerase mu 2 4
MIRT620966 TM4SF5 transmembrane 4 L six family member 5 2 2
MIRT625853 SLC35C2 solute carrier family 35 member C2 2 2
MIRT626209 PNRC1 proline rich nuclear receptor coactivator 1 2 4
MIRT626918 HIST1H2BG histone cluster 1 H2B family member g 2 2
MIRT633110 CBX5 chromobox 5 2 2
MIRT634086 APOH apolipoprotein H 2 2
MIRT634943 GTF2H2C GTF2H2 family member C 2 4
MIRT640022 OSTM1 osteopetrosis associated transmembrane protein 1 2 2
MIRT641694 SPCS1 signal peptidase complex subunit 1 2 2
MIRT645203 POLR3F RNA polymerase III subunit F 2 2
MIRT656319 MELK maternal embryonic leucine zipper kinase 2 2
MIRT659545 CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5 2 2
MIRT662395 ICA1L islet cell autoantigen 1 like 2 4
MIRT663613 SEC23B Sec23 homolog B, coat complex II component 2 2
MIRT663940 ZNF554 zinc finger protein 554 2 2
MIRT664216 LSM3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated 2 2
MIRT664382 CYB5A cytochrome b5 type A 2 2
MIRT673122 MFSD2A major facilitator superfamily domain containing 2A 2 2
MIRT677143 DEGS1 delta 4-desaturase, sphingolipid 1 2 2
MIRT677249 C15orf40 chromosome 15 open reading frame 40 2 2
MIRT678736 SRCAP Snf2 related CREBBP activator protein 2 2
MIRT679721 FBXL2 F-box and leucine rich repeat protein 2 2 2
MIRT680362 GATAD1 GATA zinc finger domain containing 1 2 4
MIRT680689 ZNF785 zinc finger protein 785 2 2
MIRT680767 WDR73 WD repeat domain 73 2 2
MIRT681399 RMND1 required for meiotic nuclear division 1 homolog 2 2
MIRT681693 ABI2 abl interactor 2 2 2
MIRT681829 N4BP2L2 NEDD4 binding protein 2 like 2 2 2
MIRT682320 RAB42 RAB42, member RAS oncogene family 2 2
MIRT683318 C19orf40 Fanconi anemia core complex associated protein 24 1 1
MIRT683388 ESR2 estrogen receptor 2 2 2
MIRT683492 ZNF7 zinc finger protein 7 2 2
MIRT683524 C11orf54 chromosome 11 open reading frame 54 2 2
MIRT683875 OCIAD1 OCIA domain containing 1 2 2
MIRT683948 MYLK3 myosin light chain kinase 3 2 2
MIRT683977 QRFPR pyroglutamylated RFamide peptide receptor 2 2
MIRT684080 TLR7 toll like receptor 7 2 2
MIRT684133 CEP104 centrosomal protein 104 2 2
MIRT684197 MSRB2 methionine sulfoxide reductase B2 2 2
MIRT684358 BCAS4 breast carcinoma amplified sequence 4 2 2
MIRT684492 GPR137B G protein-coupled receptor 137B 2 2
MIRT684574 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT684617 GTF2IRD2B GTF2I repeat domain containing 2B 2 2
MIRT684648 PDE4C phosphodiesterase 4C 2 2
MIRT684713 LRRD1 leucine rich repeats and death domain containing 1 2 2
MIRT684742 DNAJB13 DnaJ heat shock protein family (Hsp40) member B13 2 2
MIRT684787 MYO1F myosin IF 2 2
MIRT684919 CD28 CD28 molecule 2 2
MIRT685195 DCTN5 dynactin subunit 5 2 2
MIRT685248 F2RL1 F2R like trypsin receptor 1 2 2
MIRT685316 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT685351 CCL5 C-C motif chemokine ligand 5 2 2
MIRT685519 MSH3 mutS homolog 3 2 2
MIRT685578 KCNK6 potassium two pore domain channel subfamily K member 6 2 2
MIRT685635 C12orf49 chromosome 12 open reading frame 49 2 2
MIRT685660 C11orf1 chromosome 11 open reading frame 1 2 2
MIRT685709 BHMT2 betaine--homocysteine S-methyltransferase 2 2 2
MIRT685742 C12orf65 chromosome 12 open reading frame 65 2 2
MIRT685783 ZNF426 zinc finger protein 426 2 2
MIRT685883 RTN2 reticulon 2 2 2
MIRT685955 PTGIS prostaglandin I2 synthase 2 2
MIRT686106 TNIP3 TNFAIP3 interacting protein 3 2 2
MIRT686156 HS3ST1 heparan sulfate-glucosamine 3-sulfotransferase 1 2 2
MIRT686283 WWC1 WW and C2 domain containing 1 2 2
MIRT686321 VPS53 VPS53, GARP complex subunit 2 2
MIRT686362 USP15 ubiquitin specific peptidase 15 2 2
MIRT686390 UBE2V2 ubiquitin conjugating enzyme E2 V2 2 2
MIRT686444 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT686491 TRIOBP TRIO and F-actin binding protein 2 2
MIRT686527 TRAF3IP2 TRAF3 interacting protein 2 2 2
MIRT686582 TMOD3 tropomodulin 3 2 2
MIRT686693 TIMM10 translocase of inner mitochondrial membrane 10 2 2
MIRT686827 SLC7A11 solute carrier family 7 member 11 2 2
MIRT686880 SLC1A5 solute carrier family 1 member 5 2 2
MIRT686914 SGTB small glutamine rich tetratricopeptide repeat containing beta 2 2
MIRT686980 SERINC1 serine incorporator 1 2 2
MIRT687044 RNF115 ring finger protein 115 2 2
MIRT687079 RABGAP1L RAB GTPase activating protein 1 like 2 2
MIRT687254 PDHB pyruvate dehydrogenase E1 beta subunit 2 2
MIRT687596 MANEAL mannosidase endo-alpha like 2 2
MIRT687650 LRIF1 ligand dependent nuclear receptor interacting factor 1 2 2
MIRT687858 ISCA2 iron-sulfur cluster assembly 2 2 2
MIRT687983 GTF2IRD2 GTF2I repeat domain containing 2 2 2
MIRT688123 GEMIN8 gem nuclear organelle associated protein 8 2 2
MIRT688217 FKBP14 FK506 binding protein 14 2 2
MIRT688275 FAM213A family with sequence similarity 213 member A 2 2
MIRT688487 DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 2 2
MIRT688506 DDI2 DNA damage inducible 1 homolog 2 2 2
MIRT688830 CAPZA2 capping actin protein of muscle Z-line alpha subunit 2 2 2
MIRT689174 ZNF665 zinc finger protein 665 2 2
MIRT689799 GTF2H3 general transcription factor IIH subunit 3 2 2
MIRT689844 HIST1H2BJ histone cluster 1 H2B family member j 2 2
MIRT690739 IRAK4 interleukin 1 receptor associated kinase 4 2 2
MIRT690984 ZNF578 zinc finger protein 578 2 2
MIRT691076 NUGGC nuclear GTPase, germinal center associated 2 2
MIRT691333 KIAA1841 KIAA1841 2 2
MIRT691497 FOXRED2 FAD dependent oxidoreductase domain containing 2 2 2
MIRT691578 CCDC125 coiled-coil domain containing 125 2 2
MIRT691614 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT692074 ACOT9 acyl-CoA thioesterase 9 2 2
MIRT692111 CXorf38 chromosome X open reading frame 38 2 4
MIRT692212 NOL9 nucleolar protein 9 2 2
MIRT692320 RFK riboflavin kinase 2 2
MIRT692382 LY6G5B lymphocyte antigen 6 family member G5B 2 2
MIRT692443 METTL8 methyltransferase like 8 2 2
MIRT692478 APEX2 apurinic/apyrimidinic endodeoxyribonuclease 2 2 2
MIRT692546 PARD3 par-3 family cell polarity regulator 2 2
MIRT692607 GDF5OS growth differentiation factor 5 opposite strand 2 2
MIRT692788 SYNPO2L synaptopodin 2 like 2 2
MIRT692819 C1orf50 chromosome 1 open reading frame 50 2 2
MIRT692881 RBM41 RNA binding motif protein 41 2 2
MIRT692991 LGSN lengsin, lens protein with glutamine synthetase domain 2 2
MIRT693140 THEM4 thioesterase superfamily member 4 2 2
MIRT693353 RNF34 ring finger protein 34 2 2
MIRT694113 ZNF446 zinc finger protein 446 2 2
MIRT694197 ZNF347 zinc finger protein 347 2 2
MIRT694663 C14orf119 chromosome 14 open reading frame 119 2 2
MIRT694817 STX4 syntaxin 4 2 2
MIRT694939 ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 2 2
MIRT695183 SLC25A33 solute carrier family 25 member 33 2 2
MIRT695309 PIGO phosphatidylinositol glycan anchor biosynthesis class O 2 2
MIRT695663 MAN2B2 mannosidase alpha class 2B member 2 2 2
MIRT695836 ABCG8 ATP binding cassette subfamily G member 8 2 2
MIRT695928 ZNF174 zinc finger protein 174 2 2
MIRT695975 EIF2B2 eukaryotic translation initiation factor 2B subunit beta 2 2
MIRT696186 GNB5 G protein subunit beta 5 2 2
MIRT696447 SUGP1 SURP and G-patch domain containing 1 2 2
MIRT696863 UBOX5 U-box domain containing 5 2 2
MIRT696910 C14orf105 coiled-coil domain containing 198 2 2
MIRT697249 ZYG11A zyg-11 family member A, cell cycle regulator 2 2
MIRT697394 ZMAT3 zinc finger matrin-type 3 2 2
MIRT697988 TSPAN6 tetraspanin 6 2 2
MIRT698334 TMEM127 transmembrane protein 127 2 2
MIRT699274 SLC6A4 solute carrier family 6 member 4 2 2
MIRT699321 SLC35F5 solute carrier family 35 member F5 2 4
MIRT699637 SH3BP5 SH3 domain binding protein 5 2 2
MIRT699699 SF3B3 splicing factor 3b subunit 3 2 2
MIRT700048 RPL14 ribosomal protein L14 2 2
MIRT700106 RNF19B ring finger protein 19B 2 2
MIRT701114 PAPD5 poly(A) RNA polymerase D5, non-canonical 2 2
MIRT701298 NUDT3 nudix hydrolase 3 2 2
MIRT701579 MYPN myopalladin 2 2
MIRT702529 KCND3 potassium voltage-gated channel subfamily D member 3 2 2
MIRT703095 GPRIN3 GPRIN family member 3 2 2
MIRT704114 DRAXIN dorsal inhibitory axon guidance protein 2 2
MIRT704149 DNAL1 dynein axonemal light chain 1 2 2
MIRT704201 LDHD lactate dehydrogenase D 2 2
MIRT704466 CPT1A carnitine palmitoyltransferase 1A 2 2
MIRT704767 CDKN2AIPNL CDKN2A interacting protein N-terminal like 2 2
MIRT705088 C4orf29 abhydrolase domain containing 18 2 2
MIRT705353 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 2 2
MIRT706109 ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 2 2
MIRT706280 SLC35F6 solute carrier family 35 member F6 2 2
MIRT706315 CCDC30 coiled-coil domain containing 30 2 2
MIRT706355 STAC2 SH3 and cysteine rich domain 2 2 2
MIRT706407 HAS2 hyaluronan synthase 2 2 2
MIRT706438 LIAS lipoic acid synthetase 2 2
MIRT706518 MTMR9 myotubularin related protein 9 2 2
MIRT707592 PCNXL2 pecanex homolog 2 2 2
MIRT708374 CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2 2
MIRT708452 MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2 2
MIRT709076 FAHD1 fumarylacetoacetate hydrolase domain containing 1 2 2
MIRT709541 ZBED1 zinc finger BED-type containing 1 2 2
MIRT709623 KBTBD6 kelch repeat and BTB domain containing 6 2 2
MIRT714310 ZNF454 zinc finger protein 454 2 2
MIRT715601 ADAM17 ADAM metallopeptidase domain 17 2 2
MIRT716544 GOLGA2 golgin A2 2 2
MIRT717807 FAM114A1 family with sequence similarity 114 member A1 2 2
MIRT719076 ACOX1 acyl-CoA oxidase 1 2 2
MIRT732364 ZBTB7A zinc finger and BTB domain containing 7A 3 1
MIRT734579 MTDH metadherin 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-520e Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miR-520e Cisplatin approved 84093 Microarray CNE cells 22614822 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-520e Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-520e Androstenedione+Anastrozole resistant cell line (MCF-7)

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