miRTarBase - #MIRT063382


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pre-miRNA Information
pre-miRNA hsa-mir-548aq   
Genomic Coordinates chr3: 185767847 - 185767904
Description Homo sapiens miR-548aq stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-548aq-5p
Sequence 1| GAAAGUAAUUGCUGUUUUUGCC |22
Evidence Not_experimental
Experiments
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 7 3 - 185767898 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs148741643 4 dbSNP
rs373424261 5 dbSNP
rs954388082 9 dbSNP
rs1008952958 10 dbSNP
rs1443286362 15 dbSNP
rs778852684 17 dbSNP
rs1042518237 21 dbSNP
rs1299293460 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol ETNK1   
Synonyms EKI, EKI 1, EKI1, Nbla10396
Description ethanolamine kinase 1
Transcript NM_018638   
Other Transcripts NM_001039481   
Expression
Putative miRNA Targets on ETNK1
3'UTR of ETNK1
(miRNA target sites are highlighted)		 
>ETNK1|NM_018638|3'UTR
   1 AGAAGAGATTTAATTATTCTCCAGTAGCTGAGCAATGCTTGTGAATCTTTTCTTAAGAAATCCCAAAAAGCCAATATTAG
  81 TTAAAATTCTGTTGTTTAATTTGGTTATCTTGCTTTATAAATTATGCCTCTAAACAATCAAATCTATTTTTGAAATAGAC
 161 TGAATGATGTCAAGAAATATACCTACTGCTATCCGTATGTGGTGGATTAGAAATGTGTTAAATCTGCAAAAGGTATAAAG
 241 ATGTCAGTTTAATTTCTTTGATAATTTAACCTATGTTGTATGTGAATTATTTATTATAAACTTAGCACGATTCTGTGACT
 321 GTTTTTCTCTGTTTCACGTTCGTTGAGTGTAAGCAATGAAAATGTCCCAAATAAGTTTTTTAAGTTTTACTTTAATAAGA
 401 TTAATTTCAGTAAACATTCTAGTTGTTCAGTGTAACCTTTTTATCTTGATGCATTGTAAGTAAAATGAATCATTTACTCT
 481 TGAAATGCCAGTCATTGACTGATGTAGATAATTTAGGATTTTCATATAAAAATAGCTGTTTAGGAAGGTGAAATACATTC
 561 ACTGTCTCTGTTGGTGGTACATCTTGTTGAATTCAATATTAGAAAGTATTTCTTTTTGGGGTAATATAACTTAGAATTAA
 641 ATCCCTGTTTCTCTATGTAGTCTGGCAGTATAAATATAAATATTTACCATATAATCTTGGAATAAGTATTAGTTAATGTT
 721 ACCAAAATCTGTATTAAATAATGTTTTCAAATGCTAAATATGGTCGTTACTATTTTCAGTTTTAAAAATTTTATAGTATC
 801 AAATTGTTTCTAACCAAAAATTTCCTTTTACTTCTAGAGATGCTTTATGTTTTTGATTATTAAATAGTCACTAGTATTGC
 881 TAATTTTTGAAACAAATACACAAAATTTATCATATGTAGAAATAAGAAAATATTGTTTAGGTTAATTATTTTTTACCTAT
 961 CCAGAGTCATTCCTTACATTTCAGTTTCATGTTTCATTCCTCACATTTTAGTTTCATGTTTTAGTTTGATTCTATGTTTT
1041 TAGACTGATAGCAAATGATTACTTGATACATGTAAGTTCAGCGTTATATGTTGAGGCAGTTATATAATTAAATAAGGAAC
1121 ACTTAGGGCATTGATCTTGTACACTTAAAATCTGACAAATGACAAAATGTGAATTAAGCATAAATAGTCATGGCAGGAGG
1201 GCTTTTGTTTATTTCTCTTGTTTTTGTTTAACTGTATTTTTAATTTTGTCTGGTGGTAAGAGGGAGGTAATTATTGTATG
1281 GAAAGAAGTTAGATCTTTCAGATAGATAAATAGGCTTCAGGTTTTGAAGTCTGCTCTGTGTAGTTGAGCAGTCATGGTTA
1361 ACTTTACTTAGAAAATTAGTCTGACAAGCTTTGCACTTCGGTCACATAAGTGCCCATGTACAAAGTTGGCTTACTGGATC
1441 TGCATATTCAAAATATGCAACTACAAATTTATCCTCTGAGAAATCTTCTGAGGAGTCTAATGTATTCCAAATGACTTAAT
1521 ATTCTCAGACAAATGCTTTAAAATACTTGGATTATCTCAAGATTTTTGAAGCTAATAAAGTAAATAGAAACACAGGCCAT
1601 TTTAAATGGTAAATTCTAGTTACATAAATATAATCTTAAAGTATGTTTGTATCTGTAACAGTGTTAGACCAGATTTGGTT
1681 TCTACCTCCCCAATGTTATAAATGTTCACTTTTGTTTTTATAAACCATATTACTGTAAGATCAATAGAACTTTGCCTAGT
1761 TAAGTGAATGGAACCAATTAAACAACTAGTAGCTTTTTATAATGTTAGTGTGAACTTGAAAAATTGTTTTTGGTGGAATT
1841 TTTGTCTGTGGTTAGAACATTTTCATAAAACAGATAAAGAATGTGTAATACTCTTAATTTTTTTTTTTTTTTTTTTTTTT
1921 TTTTTGCTTTCTGCCTTCTAAAGTGCAACAGTATATATCTTGTAGAACTGTGGGAGGAGAGAAGATAATTTTTCTACCTT
2001 ACTCCATATTCTTACTTCAAACTATTTTGAATAGAGGTTCACTGAGCCATTGCTGATAGACTGTGCATAGCTACTAGCTG
2081 TCACACTATTGTAGGTTTTTTGGAGAGATTCATAGGGAAGTGAATGTAACCAGGAATAAAGGCTCTCACTTTAGCTCTGG
2161 GACTATGCAGTGGATCTTGGGAACAAAATAAGATATCTAATCTATTTTCCCCATTCTGGCTAGATTTTGGTTGTTGTGAT
2241 GCTCCTACTTCCTGTATAGGTTTTTGGGATCATGGTGCAGGCTAGTAATAGGATTCAGAATTGCTTCCCTTTTATATCGA
2321 CCATGTAAGGGATTCTAAAGGAGGGTAAATCTCAAAGTGCTCTGAAATCATCCCTCTAAAATCTGTCCTGTGGTGTGCTA
2401 AGATGTCTGTTGCCTTTTTATGTTAAGCTAAGGAACTTGAATGCCTTACCTAATAACTCAACTAGTAGTAAGCTCATTTT
2481 GTAAATATGAAAATGGCTGTAAGAAGTGGCATTCATGTATATTCAATGTTAGTCAATAGACCATAGTGGCCTGGATGCTT
2561 TAACAAGCCAAATTCCGCAATTTTTTTTCCTTTTTTCCCCTTCATACTTGTATGATCTCACCTGACCAGTGATTTCTTTT
2641 CCTCCTAACCCCATGCTACCACCATTTTCTGGAAATCAAAGAGATGTGGTAGTAAATCATACAGTACACACGATCATCTG
2721 AGATCAATATGAGCACAAAACTCATCAAGTAGGTCTGCCTGGAATGTATATAAAAAATGTAAATAAAAATTTGTAAATTA
2801 GTGTGAACTGTATCTTGCATATGAGACTGTGTATTGTTTTGCATTCTCTTCCCTTTTGTAGAAATTTTTCTGTAAGGAAA
2881 TGATTCAGCTTGTTGGTTTTAGAGTAAAAATAGCCAACAGTTGTGGCTACACAGTGAGATCACAGGAACTGGAAATAGGG
2961 TTTGTCGGCTTTGGTTAATGTCAGTACTCATTTATTTAGCCTCTCAGTGCTTAATAAGACTTTTCTTTATTTTTTAGTTA
3041 GCCGTTAGGTTTTGTGAGGTTAGATTCCTGGAAGCAGTGAATTTATACACTGTTATATTAATAGAGCTCCGTTCTTTGAG
3121 TCATGATTCCAAGCTAAAGGAAATTAAAAATGTAATTTAATAATTTCCTATTTTTAGGGTTGTTAATTTTTTTCTACAAA
3201 AAAACCTTGAAATTTTAGATATCCCAATGTGAATCTAATTTCCATATATACAGAAATTAGACAAATAATAAGTCTTTAGT
3281 TCAACTTAAGCATATCTCAAATGACTTCTCTAAATTTAAAGTTGATCATGATAGGATCATAAAAGACAGAAAAGACTTAA
3361 GTAATCTTGTAATGACAATTATTTCCATTTTTGCTGAACTAAAAATATTTAACTTCATAAATATGTTACTACAGCTTCCA
3441 GATTTAAAGAAAAAAAGTTTCCCCCACTCTCAATTAAAAGTTAGAACCCTCCACTTTTAAAATTATACAAATATTTCTTT
3521 TTTACATTACACAGAAGCCTTCTGTACCATTTTACGAATTTCTGTCTTCATAATATAAGTGAAAATACTGTCATTTCAAT
3601 TTTCTGCTTTAAATTGTTTTTAATAAGCATTCCAAAGTGATACAGACTTAAGCTTTTAATCAATCAGTCATTCAGTTGAT
3681 AGACAAAGTTAGCGATGCTTTATGCTAGGAAACTTGTTGACAGTAACCTGTGCGACTTTATGCAGAAGACAAATGCTAGT
3761 AATTATTATGCACAGAGGAAAAATCATTTTAAGTATGTGGTAAAGCAGCTTCATCTTTCAAAATTGATTTGCTCTGGTTT
3841 TTCTTTAGTCCATTAGATTCCAGAATGTCCTTTTACTGGGAATTTAGTTATGTATTAAGATAACCTGTTTTCAGTTCTTT
3921 TTGAAAAGAAGACATTATTTATATTGAACCACCTTATTTTAAAATTTTTAACTTTTATATACCACTTGTGTGATTCCAGT
4001 GTCATGTCTTGGGTTTGATGTCGTTGGACAGAAAAGTGTATCAATTATTTTAAATGAATTTTTCCCCATGTTTGAGGCTT
4081 AGTCTGTAAATGTGTTGCTGTAACAGAAAATACTTGGGTATGCATTACTTGAATACTTGAAAACTGAAATTAATAAGATG
4161 TATTACATAATGAATTAGATTTCTCTGAACAGTTTTTACACTGAAAATCTTCATTTCTGGATTGCAGTTTGAAATGGAAT
4241 GAAGACCTGAATTATTTGGGTAGAAAAAATTATGATAGTGCTTATAAGAACTGTAAACTGTTTTAAACTATTTTGTGTTT
4321 GACGCATCAAACTTCAAGTTTTTTGTAAGTTTCTCTCCTGAAATTTTCTTTCTCTTCTATACTTTATGCACTTACTATAC
4401 TACTGATGTAATAAAAGAGCAGGGTTAAAAATATTGTATCTGTATTCATTGTGAATCCTGTAGCTTTTCTAGTTAACAAA
4481 AAATCGCTTTCTAAAATACTCTTAATCCCATTGTTTTGGTTAACATCTTACCCATTTGTTGTATTTCAAATGCCATTAAT
4561 CATTTTAGTACAACACCTATGTTTATAAAAATTTGAAAACATTACATATTGTATTTAAAACTAATTAGTGAAGAGTAAGA
4641 AAAAAACTAGCCAACAGAATTGTAGGTGATGCATTAGTTAAATTTCAAAACTCATAATAAAGGAACTTTCAGAGATTGGT
4721 TGAAACCCAGTGGTATCCCTGTAAATTAGCTCCTGTGACTGGAAAAGACCCCAAAAAGGCAGTAGAGGAGATTAGTGTTT
4801 ACTTGCTGTGGTTGTGGTGTGCTGCTACTTAATTATAGGTAGTGACACACTGAAATTCTTATTTGTCCAATAATCTGAAG
4881 TAGTTTCCTATATTTATCTGTACTAAATTGACTATAAATTGAGTCTGCAAAGAGGAAACTTTTTGACTGTACTGTATTTA
4961 GGAGCCTTTGTACAGCTTGGTCAAATTTCCATGATATGAAGTATTTGAGTTTTAAAATATACTGTTATTAAAAGGAAAAA
5041 GACATGGCCATTATTCCATGTGCTTAAATGATAATTTCCTTATTCAGTTTCAGAAGAAAAAGAATGAAATTGGGTAACTG
5121 TCATTGCGTTAGCTTTATGTTGAATTGGGAAATTGTGGCATAAAGCTTAAATTCGTGTTTATCAAATGTGAACCATAGTA
5201 GTATAATGCTGCTTTGTATATAATGTAAGTGCTACAAATAGTCTCAGCACTGAAAATGTATTGATACCTCTTAAATGAAT
5281 GCAACTTTTGATGTAGGTGTTTTGCTATGCCTCAGAAAATATCTGTCTGAGAATTTGTTAATCTGTTTGATAATGAAGAT
5361 ACTTCCTGTTTTCTTGTTTCATATTTTCATGTTCAAAATTTAAGTTTTACATTTTTACTACTGTTAATTTAAATAAAATT
5441 TGTTCTGTGGATAAAATGAGGTTGGCAGTGAAGAAAATTAAAAACAGCCTCATTCATGTAACTGGTTAAGTAAAAATACA
5521 TTTTCACTATGTGTTCATAAACTTTTAATGAAGCTGTTTGTCTTTCAGTTCAAATATAAGTGATGTTTAGGCTTTATTTC
5601 TGTTAATAAGGCTTTTTACCATTGATTAAATGAAGGAATGTATCTTTTTGAAGAGATTTATATTCTGTAAATAAAAATTC
5681 GTTGTAACAATAAAGTTGAGTTCTAACTACAGTGTATTCA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ccGUUUUU----GUCGUUAAUGAAAg 5'
            ||:|||    :| ||||||:||| 
Target 5' gaCAGAAAAGTGTATCAATTATTTTa 3'
 4027 - 4052 154.00 -9.00
2 
miRNA  3' ccGUUU--UUGUCGU----UAAUGAAag 5'
            :|:|  :|:||||    |||||||  
Target 5' ttTAGACTGATAGCAAATGATTACTTga 3'
 1039 - 1066 140.00 -8.10
3 
miRNA  3' ccgUUUUUGUCGUUAAUGAAag 5'
             :|:| :||:: ||||||  
Target 5' gagGAGATTAGTGTTTACTTgc 3'
 4785 - 4806 139.00 -7.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31479638 6 COSMIC
COSN30479925 23 COSMIC
COSN31497651 27 COSMIC
COSN30466250 53 COSMIC
COSN24312772 58 COSMIC
COSN30474220 64 COSMIC
COSN30158886 98 COSMIC
COSN1146256 108 COSMIC
COSN19646404 109 COSMIC
COSN26175414 140 COSMIC
COSN30167621 149 COSMIC
COSN7322721 279 COSMIC
COSN1146257 329 COSMIC
COSN20092536 381 COSMIC
COSN16449994 736 COSMIC
COSN20109339 800 COSMIC
COSN7612998 1035 COSMIC
COSN4701929 1091 COSMIC
COSN30544896 1096 COSMIC
COSN30545022 1117 COSMIC
COSN31519152 1150 COSMIC
COSN30545029 1162 COSMIC
COSN31542043 1197 COSMIC
COSN30541165 1240 COSMIC
COSN31522321 1257 COSMIC
COSN22711525 1265 COSMIC
COSN31480830 1332 COSMIC
COSN30545027 1481 COSMIC
COSN31515377 1542 COSMIC
COSN28111783 1569 COSMIC
COSN31593982 1615 COSMIC
COSN31547662 1636 COSMIC
COSN30159367 1711 COSMIC
COSN31585329 1748 COSMIC
COSN19501468 1844 COSMIC
COSN15677893 1988 COSMIC
COSN25789434 2053 COSMIC
COSN1567314 2107 COSMIC
COSN26349263 2332 COSMIC
COSN31563726 2450 COSMIC
COSN31588386 2555 COSMIC
COSN31565665 2565 COSMIC
COSN22807082 2589 COSMIC
COSN26808666 2705 COSMIC
COSN27685454 2764 COSMIC
COSN31541269 2804 COSMIC
COSN31539166 2825 COSMIC
COSN8585873 2869 COSMIC
COSN31881820 2881 COSMIC
COSN20092537 2984 COSMIC
COSN5938735 3308 COSMIC
COSN8705943 3519 COSMIC
COSN31546818 3660 COSMIC
COSN25401860 3979 COSMIC
COSN25398957 4025 COSMIC
COSN7322722 4354 COSMIC
COSN20617071 4357 COSMIC
COSN22386145 4380 COSMIC
COSN27159974 4674 COSMIC
COSN25929220 4788 COSMIC
COSN20092538 4853 COSMIC
COSN7322723 4895 COSMIC
COSN31523679 4999 COSMIC
COSN31567741 5018 COSMIC
COSN31588109 5055 COSMIC
COSN31563727 5151 COSMIC
COSN21090763 5175 COSMIC
COSN31549270 5238 COSMIC
COSN30540805 5278 COSMIC
COSN31565944 5332 COSMIC
COSN20092539 5362 COSMIC
COSN31568879 5542 COSMIC
COSN31606781 5614 COSMIC
COSN31607870 5638 COSMIC
COSN28633573 5661 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1231807419 5 dbSNP
rs1309931478 7 dbSNP
rs377113417 11 dbSNP
rs539842901 22 dbSNP
rs1327869403 25 dbSNP
rs1360800265 26 dbSNP
rs181367012 28 dbSNP
rs1352799615 31 dbSNP
rs1435336407 32 dbSNP
rs1364976306 34 dbSNP
rs1318905779 35 dbSNP
rs781436816 35 dbSNP
rs745969645 39 dbSNP
rs1381372265 42 dbSNP
rs1285156741 43 dbSNP
rs369665317 44 dbSNP
rs1224722581 45 dbSNP
rs780747349 46 dbSNP
rs749812731 48 dbSNP
rs535450267 52 dbSNP
rs779162414 53 dbSNP
rs987525040 55 dbSNP
rs1464663973 64 dbSNP
rs929561018 67 dbSNP
rs1169515559 75 dbSNP
rs12316161 79 dbSNP
rs778414521 80 dbSNP
rs138515741 81 dbSNP
rs541295954 111 dbSNP
rs1256865117 113 dbSNP
rs920055279 128 dbSNP
rs1482017491 136 dbSNP
rs1421118890 139 dbSNP
rs1012913763 161 dbSNP
rs931416035 166 dbSNP
rs1228725794 179 dbSNP
rs1340958202 182 dbSNP
rs1295876506 183 dbSNP
rs1247354691 187 dbSNP
rs771061531 192 dbSNP
rs186999399 195 dbSNP
rs908618360 196 dbSNP
rs1462377604 206 dbSNP
rs1394775711 218 dbSNP
rs377529341 222 dbSNP
rs577431418 223 dbSNP
rs1372528867 231 dbSNP
rs1308665480 240 dbSNP
rs1429365661 242 dbSNP
rs1388485359 243 dbSNP
rs938717813 246 dbSNP
rs1002923339 248 dbSNP
rs1035275354 249 dbSNP
rs1057440639 267 dbSNP
rs1368808213 271 dbSNP
rs956541399 274 dbSNP
rs771257770 279 dbSNP
rs543185232 283 dbSNP
rs988489248 287 dbSNP
rs1205176776 291 dbSNP
rs1022201900 294 dbSNP
rs1310525737 297 dbSNP
rs894402397 305 dbSNP
rs562651938 306 dbSNP
rs1357549289 311 dbSNP
rs1283938473 316 dbSNP
rs967722806 326 dbSNP
rs1042931612 328 dbSNP
rs776629924 330 dbSNP
rs985759472 338 dbSNP
rs759772817 339 dbSNP
rs1368778358 342 dbSNP
rs1325834377 343 dbSNP
rs1406139380 348 dbSNP
rs998675868 349 dbSNP
rs1162384720 368 dbSNP
rs1459821107 372 dbSNP
rs141163915 374 dbSNP
rs890200438 375 dbSNP
rs919438321 377 dbSNP
rs770047319 381 dbSNP
rs548340922 382 dbSNP
rs1017654030 385 dbSNP
rs1230650923 392 dbSNP
rs929477192 393 dbSNP
rs1049812344 396 dbSNP
rs1451777649 396 dbSNP
rs964329200 403 dbSNP
rs1331660800 405 dbSNP
rs374911721 411 dbSNP
rs370988717 414 dbSNP
rs1456431021 417 dbSNP
rs34490298 423 dbSNP
rs975613355 426 dbSNP
rs1027122605 427 dbSNP
rs1276651657 430 dbSNP
rs776159273 431 dbSNP
rs952909333 432 dbSNP
rs982892841 433 dbSNP
rs1330681583 435 dbSNP
rs1322657062 440 dbSNP
rs1180359514 452 dbSNP
rs1459740011 453 dbSNP
rs1044422855 467 dbSNP
rs1413404102 469 dbSNP
rs1159874570 471 dbSNP
rs1456608680 474 dbSNP
rs1475559250 480 dbSNP
rs1405200764 489 dbSNP
rs562093001 505 dbSNP
rs960390450 506 dbSNP
rs528011316 509 dbSNP
rs1191349837 512 dbSNP
rs548087781 525 dbSNP
rs1002974039 534 dbSNP
rs915875825 536 dbSNP
rs1208685579 555 dbSNP
rs948680761 558 dbSNP
rs746134393 565 dbSNP
rs1043025348 575 dbSNP
rs925843038 581 dbSNP
rs1344392241 582 dbSNP
rs1356679072 583 dbSNP
rs191738259 586 dbSNP
rs577984988 597 dbSNP
rs560095587 603 dbSNP
rs890219109 613 dbSNP
rs967943380 625 dbSNP
rs1434306438 627 dbSNP
rs1343295923 629 dbSNP
rs1354497555 638 dbSNP
rs1009023074 652 dbSNP
rs1233345707 658 dbSNP
rs1336090323 662 dbSNP
rs1382005611 669 dbSNP
rs1414603754 671 dbSNP
rs1423834031 673 dbSNP
rs1171408882 675 dbSNP
rs1450901809 677 dbSNP
rs540044656 689 dbSNP
rs1391194255 690 dbSNP
rs1038715221 707 dbSNP
rs1485180056 709 dbSNP
rs550354530 718 dbSNP
rs184027698 719 dbSNP
rs994446893 730 dbSNP
rs1217968955 734 dbSNP
rs375195492 766 dbSNP
rs761731500 767 dbSNP
rs976265388 773 dbSNP
rs1237116185 776 dbSNP
rs752184013 784 dbSNP
rs72185722 798 dbSNP
rs866000936 801 dbSNP
rs1016139385 812 dbSNP
rs1213845943 815 dbSNP
rs569804942 826 dbSNP
rs1285938869 834 dbSNP
rs1448635894 855 dbSNP
rs1374354206 856 dbSNP
rs1261132895 861 dbSNP
rs535539618 864 dbSNP
rs12317915 869 dbSNP
rs1370721510 875 dbSNP
rs984978454 879 dbSNP
rs1169026813 884 dbSNP
rs1422337809 892 dbSNP
rs1416381852 894 dbSNP
rs1182993419 896 dbSNP
rs1413094623 902 dbSNP
rs1472732071 912 dbSNP
rs1255515375 913 dbSNP
rs1175862323 942 dbSNP
rs970070441 956 dbSNP
rs909345089 962 dbSNP
rs750385766 964 dbSNP
rs978756486 968 dbSNP
rs1415019264 972 dbSNP
rs1314560665 974 dbSNP
rs1044643184 979 dbSNP
rs928641450 980 dbSNP
rs1411194128 998 dbSNP
rs938653635 1016 dbSNP
rs571990797 1028 dbSNP
rs925895227 1030 dbSNP
rs1352015566 1032 dbSNP
rs1165867200 1033 dbSNP
rs934530879 1035 dbSNP
rs1337805632 1036 dbSNP
rs1472988582 1044 dbSNP
rs1175732514 1046 dbSNP
rs891877999 1049 dbSNP
rs1267010831 1050 dbSNP
rs534286908 1053 dbSNP
rs1333885197 1055 dbSNP
rs1271255050 1061 dbSNP
rs1230125068 1063 dbSNP
rs1012037447 1069 dbSNP
rs558053532 1070 dbSNP
rs944484948 1072 dbSNP
rs1043575721 1077 dbSNP
rs903668419 1082 dbSNP
rs1369211228 1083 dbSNP
rs1007450297 1084 dbSNP
rs1440714014 1085 dbSNP
rs1017456829 1088 dbSNP
rs764018312 1096 dbSNP
rs1363326975 1098 dbSNP
rs577467868 1104 dbSNP
rs552262168 1105 dbSNP
rs900229748 1108 dbSNP
rs751432540 1114 dbSNP
rs1268404567 1115 dbSNP
rs950503151 1120 dbSNP
rs1048704068 1127 dbSNP
rs1467904127 1129 dbSNP
rs556735408 1137 dbSNP
rs187364222 1149 dbSNP
rs1016457595 1165 dbSNP
rs1329721955 1169 dbSNP
rs1283916448 1171 dbSNP
rs1236169789 1174 dbSNP
rs1487992185 1188 dbSNP
rs542294325 1189 dbSNP
rs1301605646 1197 dbSNP
rs201147670 1199 dbSNP
rs749728658 1204 dbSNP
rs1369283683 1208 dbSNP
rs1322911133 1211 dbSNP
rs970193084 1231 dbSNP
rs1244320389 1233 dbSNP
rs980377185 1237 dbSNP
rs1004400410 1241 dbSNP
rs1477332608 1249 dbSNP
rs1467701636 1253 dbSNP
rs1190903751 1255 dbSNP
rs1378250828 1257 dbSNP
rs1173287581 1261 dbSNP
rs1452763427 1262 dbSNP
rs1396097501 1264 dbSNP
rs1434898560 1266 dbSNP
rs562008074 1277 dbSNP
rs1393057828 1290 dbSNP
rs928865824 1300 dbSNP
rs368140470 1303 dbSNP
rs1483971441 1310 dbSNP
rs1256032796 1311 dbSNP
rs988831737 1317 dbSNP
rs913191925 1321 dbSNP
rs1300277520 1337 dbSNP
rs1015778390 1350 dbSNP
rs1043100183 1355 dbSNP
rs1294117824 1361 dbSNP
rs903720846 1366 dbSNP
rs1403037483 1374 dbSNP
rs1312293968 1384 dbSNP
rs960516880 1389 dbSNP
rs1014409026 1390 dbSNP
rs1328070452 1395 dbSNP
rs943197527 1400 dbSNP
rs1475651086 1401 dbSNP
rs527708735 1407 dbSNP
rs541021922 1410 dbSNP
rs1425437136 1422 dbSNP
rs1023510470 1424 dbSNP
rs997808970 1426 dbSNP
rs1025990629 1427 dbSNP
rs1276410310 1439 dbSNP
rs1302365930 1445 dbSNP
rs1339180259 1453 dbSNP
rs545670617 1460 dbSNP
rs1249933311 1463 dbSNP
rs886078589 1467 dbSNP
rs12312458 1477 dbSNP
rs368508362 1481 dbSNP
rs1341529154 1484 dbSNP
rs753350750 1496 dbSNP
rs774323107 1500 dbSNP
rs1352396761 1501 dbSNP
rs1032972469 1503 dbSNP
rs1236286212 1505 dbSNP
rs955958070 1522 dbSNP
rs1350321049 1540 dbSNP
rs1165880133 1546 dbSNP
rs1459388538 1561 dbSNP
rs754515271 1575 dbSNP
rs200138533 1584 dbSNP
rs1473969705 1597 dbSNP
rs1253303585 1598 dbSNP
rs1182114983 1599 dbSNP
rs1436811198 1608 dbSNP
rs778750102 1618 dbSNP
rs1286431476 1620 dbSNP
rs1450349346 1622 dbSNP
rs1221502935 1624 dbSNP
rs1016007130 1625 dbSNP
rs11046535 1631 dbSNP
rs764190513 1632 dbSNP
rs1331356334 1634 dbSNP
rs911799023 1634 dbSNP
rs1035823971 1635 dbSNP
rs757017372 1671 dbSNP
rs141532899 1688 dbSNP
rs1441769769 1690 dbSNP
rs754014240 1691 dbSNP
rs1378084693 1693 dbSNP
rs74068270 1694 dbSNP
rs758857992 1696 dbSNP
rs989440467 1703 dbSNP
rs1158574752 1708 dbSNP
rs974597640 1709 dbSNP
rs1386539837 1713 dbSNP
rs1469309474 1730 dbSNP
rs921718605 1742 dbSNP
rs1230888272 1746 dbSNP
rs1325116758 1751 dbSNP
rs913251041 1758 dbSNP
rs947357839 1768 dbSNP
rs1212392882 1771 dbSNP
rs930360022 1780 dbSNP
rs1306820461 1786 dbSNP
rs189725623 1798 dbSNP
rs1223360179 1811 dbSNP
rs1348618696 1814 dbSNP
rs886079022 1817 dbSNP
rs570239071 1830 dbSNP
rs1235264079 1831 dbSNP
rs1371498992 1848 dbSNP
rs2129613 1849 dbSNP
rs896067465 1854 dbSNP
rs942748149 1858 dbSNP
rs1014870983 1859 dbSNP
rs549076289 1866 dbSNP
rs1274349775 1868 dbSNP
rs1405131630 1871 dbSNP
rs773841031 1872 dbSNP
rs1454410916 1875 dbSNP
rs1197078861 1876 dbSNP
rs1394872625 1880 dbSNP
rs755194709 1881 dbSNP
rs1192069391 1888 dbSNP
rs1451715104 1892 dbSNP
rs1243261646 1894 dbSNP
rs1215683099 1896 dbSNP
rs1023100252 1897 dbSNP
rs1171351307 1898 dbSNP
rs1186480006 1898 dbSNP
rs1188660348 1898 dbSNP
rs1207533710 1898 dbSNP
rs1239296588 1898 dbSNP
rs1278527880 1898 dbSNP
rs1309078422 1898 dbSNP
rs1335554369 1898 dbSNP
rs1342955681 1898 dbSNP
rs1374545665 1898 dbSNP
rs1392103093 1898 dbSNP
rs1420632484 1898 dbSNP
rs1429897083 1898 dbSNP
rs1434955845 1898 dbSNP
rs1451779327 1898 dbSNP
rs1474683475 1898 dbSNP
rs1485381301 1898 dbSNP
rs3983448 1898 dbSNP
rs577546967 1898 dbSNP
rs5796967 1898 dbSNP
rs905949924 1899 dbSNP
rs1273395931 1900 dbSNP
rs1436825675 1900 dbSNP
rs1213932673 1902 dbSNP
rs1359699667 1905 dbSNP
rs1000256957 1912 dbSNP
rs1414929819 1925 dbSNP
rs1491331990 1925 dbSNP
rs1354248901 1926 dbSNP
rs1420971795 1926 dbSNP
rs1452591374 1927 dbSNP
rs1171705216 1928 dbSNP
rs1033023149 1930 dbSNP
rs1365235096 1930 dbSNP
rs1471506894 1931 dbSNP
rs956054550 1932 dbSNP
rs765953812 1933 dbSNP
rs1418472878 1934 dbSNP
rs1462949108 1939 dbSNP
rs1328990981 1941 dbSNP
rs1170113543 1950 dbSNP
rs1395531369 1952 dbSNP
rs372570437 1956 dbSNP
rs1019316522 1958 dbSNP
rs965978890 1963 dbSNP
rs1255451057 1965 dbSNP
rs11046536 1966 dbSNP
rs138002691 1971 dbSNP
rs1481053580 1975 dbSNP
rs561565726 1990 dbSNP
rs1233248723 1994 dbSNP
rs1203646352 1995 dbSNP
rs1016062372 1998 dbSNP
rs1275027624 2001 dbSNP
rs113726303 2007 dbSNP
rs182376718 2011 dbSNP
rs930410764 2012 dbSNP
rs1333566016 2021 dbSNP
rs1392783105 2033 dbSNP
rs771375399 2033 dbSNP
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rs571255044 2037 dbSNP
rs1337501078 2049 dbSNP
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rs1368277487 5641 dbSNP
rs1233156118 5644 dbSNP
rs1301595597 5645 dbSNP
rs1359120295 5653 dbSNP
rs1313577761 5670 dbSNP
rs929618337 5672 dbSNP
rs530900742 5673 dbSNP
rs879541522 5680 dbSNP
rs914433980 5681 dbSNP
rs779072258 5682 dbSNP
rs867383693 5685 dbSNP
rs750553462 5689 dbSNP
rs1250931271 5690 dbSNP
rs1384330080 5693 dbSNP
rs1055266441 5701 dbSNP
rs1441398398 5706 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 55500.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000266517.4 | 3UTR | AAAUUUUCUUUCUCUUCUAUACUUUAUGCACUUACUAUACUACUGAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
184 hsa-miR-548aq-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT057134 DDIT4 DNA damage inducible transcript 4 2 4
MIRT063382 ETNK1 ethanolamine kinase 1 2 2
MIRT072505 RAB8B RAB8B, member RAS oncogene family 2 2
MIRT082197 ACTN4 actinin alpha 4 2 6
MIRT083047 PTBP1 polypyrimidine tract binding protein 1 2 2
MIRT085199 SLC5A3 solute carrier family 5 member 3 2 4
MIRT088917 FOXN2 forkhead box N2 2 4
MIRT089509 MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 6
MIRT092051 ABHD5 abhydrolase domain containing 5 2 2
MIRT094694 FEM1C fem-1 homolog C 2 2
MIRT095408 UBE2D2 ubiquitin conjugating enzyme E2 D2 2 2
MIRT096514 BRIX1 BRX1, biogenesis of ribosomes 2 2
MIRT101306 FAM135A family with sequence similarity 135 member A 2 2
MIRT103369 CBX3 chromobox 3 2 2
MIRT103887 FOXK1 forkhead box K1 2 2
MIRT104347 CLDN12 claudin 12 2 2
MIRT104511 PEG10 paternally expressed 10 2 6
MIRT111811 MPZL1 myelin protein zero like 1 2 2
MIRT177250 BMI1 BMI1 proto-oncogene, polycomb ring finger 2 2
MIRT177285 COMMD3-BMI1 COMMD3-BMI1 readthrough 2 2
MIRT177635 UBE2D1 ubiquitin conjugating enzyme E2 D1 2 6
MIRT178051 SAMD8 sterile alpha motif domain containing 8 2 2
MIRT179111 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 6
MIRT179598 CAPZA1 capping actin protein of muscle Z-line alpha subunit 1 2 6
MIRT195309 LEPROT leptin receptor overlapping transcript 2 2
MIRT203155 BACH1 BTB domain and CNC homolog 1 2 2
MIRT208439 ZBTB38 zinc finger and BTB domain containing 38 2 2
MIRT214587 SMAD5 SMAD family member 5 2 4
MIRT216114 IL6ST interleukin 6 signal transducer 2 2
MIRT216366 CCNB1 cyclin B1 2 4
MIRT220062 MDFIC MyoD family inhibitor domain containing 2 2
MIRT226739 ANP32B acidic nuclear phosphoprotein 32 family member B 2 4
MIRT227708 TBC1D13 TBC1 domain family member 13 2 2
MIRT230083 SH3BGRL SH3 domain binding glutamate rich protein like 2 2
MIRT248647 HMGN2 high mobility group nucleosomal binding domain 2 2 4
MIRT254803 XRCC6 X-ray repair cross complementing 6 2 6
MIRT264390 YAP1 Yes associated protein 1 2 2
MIRT266985 LRRC55 leucine rich repeat containing 55 2 4
MIRT273960 SPRYD4 SPRY domain containing 4 2 2
MIRT281812 MAP2K1 mitogen-activated protein kinase kinase 1 2 2
MIRT293265 DR1 down-regulator of transcription 1 2 2
MIRT297107 RGPD4 RANBP2-like and GRIP domain containing 4 2 2
MIRT308184 PDE12 phosphodiesterase 12 2 2
MIRT309027 USP53 ubiquitin specific peptidase 53 2 2
MIRT311481 PRRC1 proline rich coiled-coil 1 2 2
MIRT312599 G3BP1 G3BP stress granule assembly factor 1 2 4
MIRT328139 ZNF711 zinc finger protein 711 2 2
MIRT329324 FAM53C family with sequence similarity 53 member C 2 2
MIRT334652 NEK7 NIMA related kinase 7 2 2
MIRT340683 THRAP3 thyroid hormone receptor associated protein 3 2 2
MIRT378867 ITGB8 integrin subunit beta 8 2 2
MIRT395804 SPCS3 signal peptidase complex subunit 3 2 2
MIRT405650 WBP4 WW domain binding protein 4 2 4
MIRT408296 GRPEL2 GrpE like 2, mitochondrial 2 2
MIRT442110 ZNRF2 zinc and ring finger 2 2 8
MIRT442853 GTF2H5 general transcription factor IIH subunit 5 2 2
MIRT443129 VLDLR very low density lipoprotein receptor 2 2
MIRT443160 ZDHHC21 zinc finger DHHC-type containing 21 2 2
MIRT443311 PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1 2 2
MIRT445093 ZNF207 zinc finger protein 207 2 2
MIRT445397 PTCHD1 patched domain containing 1 2 4
MIRT447083 MCC mutated in colorectal cancers 2 2
MIRT447313 ZNF562 zinc finger protein 562 2 2
MIRT447526 MRPS5 mitochondrial ribosomal protein S5 2 2
MIRT449524 TM6SF1 transmembrane 6 superfamily member 1 2 2
MIRT449915 C11orf34 placenta expressed transcript 1 1 2
MIRT450564 SHFM1 SEM1, 26S proteasome complex subunit 2 2
MIRT450732 PVRL3 nectin cell adhesion molecule 3 2 2
MIRT454936 ANKEF1 ankyrin repeat and EF-hand domain containing 1 2 12
MIRT455905 KIF2C kinesin family member 2C 2 2
MIRT463745 YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon 2 8
MIRT471195 PHB2 prohibitin 2 2 2
MIRT472777 MTMR6 myotubularin related protein 6 2 8
MIRT474470 KLHL11 kelch like family member 11 2 8
MIRT475998 GTPBP2 GTP binding protein 2 2 2
MIRT482290 AGO2 argonaute 2, RISC catalytic component 2 4
MIRT485871 ALG9 ALG9, alpha-1,2-mannosyltransferase 2 2
MIRT486205 ERH ERH, mRNA splicing and mitosis factor 2 4
MIRT488622 FAM3C family with sequence similarity 3 member C 2 6
MIRT489997 DDB1 damage specific DNA binding protein 1 2 2
MIRT493489 IPMK inositol polyphosphate multikinase 2 2
MIRT494293 CEP120 centrosomal protein 120 2 2
MIRT498005 ZBTB20 zinc finger and BTB domain containing 20 2 2
MIRT498486 PTBP2 polypyrimidine tract binding protein 2 2 10
MIRT498572 TMEM30B transmembrane protein 30B 2 2
MIRT499880 SVOP SV2 related protein 2 10
MIRT500233 INHBA inhibin beta A subunit 2 10
MIRT500707 TRIM37 tripartite motif containing 37 2 2
MIRT501001 SPPL2A signal peptide peptidase like 2A 2 4
MIRT501036 SMG1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 2 6
MIRT502749 CLIP1 CAP-Gly domain containing linker protein 1 2 8
MIRT502811 CELSR3 cadherin EGF LAG seven-pass G-type receptor 3 2 6
MIRT502900 CDK4 cyclin dependent kinase 4 2 8
MIRT503496 ZNF154 zinc finger protein 154 2 6
MIRT503730 GRM5 glutamate metabotropic receptor 5 2 2
MIRT505150 YOD1 YOD1 deubiquitinase 2 2
MIRT505815 RSBN1 round spermatid basic protein 1 2 8
MIRT505854 POLR1B RNA polymerase I subunit B 2 4
MIRT509297 NPM3 nucleophosmin/nucleoplasmin 3 2 6
MIRT516842 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT520532 TRA2B transformer 2 beta homolog 2 2
MIRT520736 TM9SF3 transmembrane 9 superfamily member 3 2 6
MIRT525416 SHISA9 shisa family member 9 2 4
MIRT525880 ARL13B ADP ribosylation factor like GTPase 13B 2 2
MIRT526026 RBM4B RNA binding motif protein 4B 2 2
MIRT526097 TMEM41B transmembrane protein 41B 2 2
MIRT527944 FRY FRY microtubule binding protein 2 2
MIRT528831 RAB32 RAB32, member RAS oncogene family 2 2
MIRT531075 SLC9A4 solute carrier family 9 member A4 2 4
MIRT535508 PANX1 pannexin 1 2 2
MIRT536695 IKZF5 IKAROS family zinc finger 5 2 2
MIRT536848 HMBOX1 homeobox containing 1 2 2
MIRT537215 GDE1 glycerophosphodiester phosphodiesterase 1 2 4
MIRT537847 EFNA5 ephrin A5 2 2
MIRT538358 CSE1L chromosome segregation 1 like 2 4
MIRT541255 GPC4 glypican 4 2 2
MIRT543248 PEX7 peroxisomal biogenesis factor 7 2 2
MIRT543463 PARP15 poly(ADP-ribose) polymerase family member 15 2 2
MIRT543724 XKR9 XK related 9 2 2
MIRT543920 ESYT1 extended synaptotagmin 1 2 2
MIRT544012 KLRC3 killer cell lectin like receptor C3 2 2
MIRT544083 METTL8 methyltransferase like 8 2 2
MIRT544200 ANGPTL3 angiopoietin like 3 2 2
MIRT544821 ACSM2B acyl-CoA synthetase medium chain family member 2B 2 2
MIRT545059 PRELID1 PRELI domain containing 1 2 2
MIRT545227 HIST1H2BD histone cluster 1 H2B family member d 2 2
MIRT545302 SPC25 SPC25, NDC80 kinetochore complex component 2 2
MIRT545563 GIMAP4 GTPase, IMAP family member 4 2 2
MIRT546510 SIK1 salt inducible kinase 1 2 2
MIRT546927 PTP4A1 protein tyrosine phosphatase type IVA, member 1 2 2
MIRT547688 KPNA1 karyopherin subunit alpha 1 2 4
MIRT547781 KATNAL1 katanin catalytic subunit A1 like 1 2 2
MIRT548700 CRNKL1 crooked neck pre-mRNA splicing factor 1 2 2
MIRT548914 CHEK2 checkpoint kinase 2 2 4
MIRT549970 RPL7L1 ribosomal protein L7 like 1 2 4
MIRT550502 TMEM241 transmembrane protein 241 2 2
MIRT551062 MKLN1 muskelin 1 2 2
MIRT552824 XIAP X-linked inhibitor of apoptosis 2 4
MIRT553158 UBE2H ubiquitin conjugating enzyme E2 H 2 2
MIRT553843 SYNCRIP synaptotagmin binding cytoplasmic RNA interacting protein 2 2
MIRT554271 SIX4 SIX homeobox 4 2 2
MIRT555794 PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 2 2
MIRT556331 MAP2K4 mitogen-activated protein kinase kinase 4 2 2
MIRT556512 LIPA lipase A, lysosomal acid type 2 2
MIRT556706 KLHL28 kelch like family member 28 2 2
MIRT556765 KLF7 Kruppel like factor 7 2 2
MIRT557003 HPRT1 hypoxanthine phosphoribosyltransferase 1 2 2
MIRT557159 HOXA13 homeobox A13 2 2
MIRT557500 GPR27 G protein-coupled receptor 27 2 4
MIRT558115 ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 2 2
MIRT559357 ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) 2 2
MIRT560348 ZWINT ZW10 interacting kinetochore protein 2 2
MIRT561312 ZBTB43 zinc finger and BTB domain containing 43 2 2
MIRT561896 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 2
MIRT561940 MFSD9 major facilitator superfamily domain containing 9 2 2
MIRT562948 TNIP2 TNFAIP3 interacting protein 2 2 2
MIRT563304 BBS10 Bardet-Biedl syndrome 10 2 2
MIRT563418 KIF3A kinesin family member 3A 2 2
MIRT563575 KIAA1586 KIAA1586 2 2
MIRT565888 NHS NHS actin remodeling regulator 2 2
MIRT566094 RCC2 regulator of chromosome condensation 2 2 2
MIRT566409 PLAGL2 PLAG1 like zinc finger 2 2 2
MIRT567272 HSP90AA1 heat shock protein 90 alpha family class A member 1 2 2
MIRT571481 CCDC80 coiled-coil domain containing 80 2 2
MIRT572952 VDAC2 voltage dependent anion channel 2 2 2
MIRT573641 ZNF724P zinc finger protein 724 2 2
MIRT573730 KHSRP KH-type splicing regulatory protein 2 2
MIRT609101 SMIM15 small integral membrane protein 15 2 6
MIRT617949 EBNA1BP2 EBNA1 binding protein 2 2 2
MIRT618392 PRKG2 protein kinase, cGMP-dependent, type II 2 2
MIRT619640 PLEKHG7 pleckstrin homology and RhoGEF domain containing G7 2 2
MIRT623468 KDM5A lysine demethylase 5A 2 2
MIRT629158 CTCFL CCCTC-binding factor like 2 2
MIRT638534 LYRM2 LYR motif containing 2 2 2
MIRT649496 CLDN16 claudin 16 2 2
MIRT683161 MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 2 2
MIRT691673 SLC43A3 solute carrier family 43 member 3 2 2
MIRT693214 MKI67 marker of proliferation Ki-67 2 2
MIRT695347 AQP3 aquaporin 3 (Gill blood group) 2 2
MIRT701036 PCGF5 polycomb group ring finger 5 2 2
MIRT708766 RYBP RING1 and YY1 binding protein 2 2
MIRT717571 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT719299 SETD7 SET domain containing lysine methyltransferase 7 2 2
MIRT725185 SDAD1 SDA1 domain containing 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-548aq Paclitaxel 36314 NSC125973 approved resistant cell line (BAS)
hsa-miR-548aq-5p Gefitinib 123631 NSC715055 approved sensitive High Non-Small Cell Lung Cancer tissue
hsa-miR-548aq-5p Erlotinib 176870 NSC718781 approved sensitive High Non-Small Cell Lung Cancer tissue
hsa-miR-548aq-5p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-548aq-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-548aq-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-548aq-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-548aq-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)

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