miRTarBase - #MIRT065800


—
pre-miRNA Information
pre-miRNA hsa-mir-6511a-1   
Genomic Coordinates chr16: 14925937 - 14926003
Description Homo sapiens miR-6511-1 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-6511a-2   
Genomic Coordinates chr16: 16324588 - 16324654
Description Homo sapiens miR-6511a-2 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-6511a-3   
Genomic Coordinates chr16: 16368876 - 16368942
Description Homo sapiens miR-6511a-3 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-6511a-4   
Genomic Coordinates chr16: 18344013 - 18344079
Description Homo sapiens miR-6511a-4 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6511a-5p
Sequence 5| CAGGCAGAAGUGGGGCUGACAGG |27
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1487543025 1 dbSNP
rs1392076032 3 dbSNP
rs1310870806 4 dbSNP
rs1254682419 4 dbSNP
rs1278331621 7 dbSNP
rs1254258380 10 dbSNP
rs1264005279 10 dbSNP
rs1422687535 10 dbSNP
rs1265836339 11 dbSNP
rs1231039877 11 dbSNP
rs778780495 11 dbSNP
rs1223241579 13 dbSNP
rs1181020448 14 dbSNP
rs1431009971 15 dbSNP
rs1356835118 21 dbSNP
rs1335107771 23 dbSNP
rs1344299836 23 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol HOXC8   
Synonyms HOX3, HOX3A
Description homeobox C8
Transcript NM_022658   
Expression
Putative miRNA Targets on HOXC8
3'UTR of HOXC8
(miRNA target sites are highlighted)		 
>HOXC8|NM_022658|3'UTR
   1 GCAAAAAAGAAAGACCCCCCCCCCCTTAGCAACTCCCTTGAAGTTTCGTTTTATGGTAGCAGATAAATTGAGAAGTTTAC
  81 GACTGTCATTTGCTTTTATAGAGAATAGAATGACACTCACAACTCTAACTACCTGTCAGATACTTGCAGCTCTGGTTTTA
 161 TTACCTTTGGACTTCCCCCACTCTTTATTTGTTTGGGGGCTGGAGGGGGGAGACGGAGAAACAGTGAAAAGTTCGGACTC
 241 TCTGTCTCACTCCTTGCCCCACACACACTTGTCCCTGCCCCCACCCTTCTGAGTCCTTCCTGGATTTTAAGGTCTGAGAC
 321 CTGGCCTCCGTGCTCCTCGGTCTGTCTCTCACCACACTCCCACCTCCCTGCTTCTCTGGTATTTATTTTAGAGGGGAGCC
 401 CCCTCGAAATGCAGAAAAGGACTTGTGGTTTTGTTTTTATGCTAAGGCTAGTGTACTAGATGTACTTTTTCTAAAAAGGA
 481 AAGGACAGAAAAAAATGAAGAAAGGAAAGGAAGACAAATGTAAAGAAATAAGGAAAAAAGCAAGGAATATCCCCTCCCCC
 561 TCCCCCTCCCCCTCCCCAGGGCTCCCTGCTTAGAAAAACCCCCTTGACTTTCTCTAGGAACCTGATGGAAACCTGAAGGA
 641 GATGTGGGTCTTTCCCCTCCCCCCATTTCCAGAAGGGTAGATAGGAGCCTGCAGTCGCCTCTAAAATCCTACCTAACCAT
 721 CCCATGGTCACTCGGGCCCATGCCTTCCTCTCCTTCGCTGTTTGATTTCTATTCTGTTGGGCCCGCCTTCCTCTGAGCTG
 801 CATTAGTGTTAGTGCTCAGAAATCACCATAATCACGAAAATAATAATAATAAATCTTTAACATACTACCTAAAGGGAACC
 881 TGCAATAATCTTGAAAAAGAAAAAGAGAAAAATTTTAAAATCCTGCTATAGGAGAAAAAAAGAGAAAAAAATAAAAATCA
 961 AAAAAAAAAAAAAGAAAGAAAGAAACCTCCAGCGTATTTTATCACTACCTATAGAAAGAAATCCTGCTTTGAGAGTATTT
1041 GTAATGCGGTTTTGTTGTCGTTTGTTGCTGCTTATTTCACTAAGAAAACCCAACAACTGAGACTGCCTAGCCCGCCGGTC
1121 CTGTGCGCTTTTATTGTGCTTCTAACCCCAGTAGAGTAGAACTAAATTGCACTGAATGTATAGTTAACTCTGTCTTGAAT
1201 TCTCTGTTTATGCAATGTGCTCGAAAGAAAAAAATGTTAAAAATATATCTATAATAATAATTTTTTGTCATTTGTCTTTA
1281 TGTCCAGCTATGAATGTAGATTTTGTGTCCCGACAGCCCTGTTCCTGGTCCAAGTACTTTGTATTGTATACGTGAGTCAT
1361 AATAATAAAAAGAAGAAGAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ggacagUCGGG-GUGA-AGACGGAc 5'
                ||::|  ||| ||||:|| 
Target 5' gtgaaaAGTTCGGACTCTCTGTCTc 3'
 224 - 248 137.00 -12.30
2 
miRNA  3' ggacaguCGGGGUG-AAGACGGAc 5'
                 ||:|| |  ||||:|| 
Target 5' cctccgtGCTCCTCGGTCTGTCTc 3'
 325 - 348 136.00 -18.20
3 
miRNA  3' ggACA-GUCGGGGUGAAGACGGAc 5'
            ||| :|| :: || ||||:|| 
Target 5' aaTGTATAG-TTAAC-TCTGTCTt 3'
 1175 - 1196 135.00 -12.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN28877271 17 COSMIC
COSN30183035 20 COSMIC
COSN30475167 23 COSMIC
COSN13404745 25 COSMIC
COSN17685096 26 COSMIC
COSN20109650 26 COSMIC
COSN5853124 28 COSMIC
COSN26979230 33 COSMIC
COSN30157612 36 COSMIC
COSN31580694 52 COSMIC
COSN17182712 82 COSMIC
COSN30149865 104 COSMIC
COSN31510392 144 COSMIC
COSN17132534 173 COSMIC
COSN30479389 177 COSMIC
COSN30459807 179 COSMIC
COSN30186913 180 COSMIC
COSN30540568 200 COSMIC
COSN18736841 305 COSMIC
COSN25634736 574 COSMIC
COSN31960797 586 COSMIC
COSN4703064 673 COSMIC
COSN30544260 688 COSMIC
COSN31515235 888 COSMIC
COSN16622007 906 COSMIC
COSN31607884 908 COSMIC
COSN32063712 953 COSMIC
COSN28826882 959 COSMIC
COSN19656442 974 COSMIC
COSN20109654 974 COSMIC
COSN26505421 975 COSMIC
COSN8339970 1041 COSMIC
COSN27388888 1127 COSMIC
COSN31490731 1155 COSMIC
COSN31489634 1208 COSMIC
COSN31570425 1261 COSMIC
COSN31485543 1263 COSMIC
COSN28201835 1306 COSMIC
COSN8586354 1313 COSMIC
COSN20092579 1353 COSMIC
COSN31528062 1369 COSMIC
COSN32056621 1370 COSMIC
COSN31603108 1372 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1450626585 3 dbSNP
rs1419518499 6 dbSNP
rs755196174 7 dbSNP
rs778876885 10 dbSNP
rs1268377040 14 dbSNP
rs747993663 14 dbSNP
rs776089647 14 dbSNP
rs1491480531 15 dbSNP
rs375330102 15 dbSNP
rs534181903 15 dbSNP
rs558229116 15 dbSNP
rs560386503 15 dbSNP
rs758594646 15 dbSNP
rs569341279 16 dbSNP
rs919343727 16 dbSNP
rs758104186 17 dbSNP
rs777820655 18 dbSNP
rs1178593674 19 dbSNP
rs755054190 20 dbSNP
rs905207946 20 dbSNP
rs781620506 21 dbSNP
rs1056660199 22 dbSNP
rs527829808 22 dbSNP
rs748659517 23 dbSNP
rs770479099 23 dbSNP
rs1181637988 24 dbSNP
rs200035305 24 dbSNP
rs201173990 25 dbSNP
rs386763147 25 dbSNP
rs35378573 26 dbSNP
rs398019654 26 dbSNP
rs4142680 26 dbSNP
rs775291126 26 dbSNP
rs1333246117 27 dbSNP
rs1480079268 31 dbSNP
rs926467312 31 dbSNP
rs762289035 35 dbSNP
rs1443968133 38 dbSNP
rs760209116 44 dbSNP
rs370624442 48 dbSNP
rs937881585 49 dbSNP
rs1306233583 50 dbSNP
rs1366339552 63 dbSNP
rs1164577726 65 dbSNP
rs116334238 69 dbSNP
rs915165769 81 dbSNP
rs945049190 82 dbSNP
rs1177249653 88 dbSNP
rs1439168445 97 dbSNP
rs1253775192 104 dbSNP
rs1211699130 108 dbSNP
rs1487653896 125 dbSNP
rs1042460736 126 dbSNP
rs1350172801 126 dbSNP
rs1354094322 127 dbSNP
rs961320268 131 dbSNP
rs550220697 133 dbSNP
rs11170784 153 dbSNP
rs1486048519 161 dbSNP
rs919755329 172 dbSNP
rs530815344 173 dbSNP
rs1387987491 178 dbSNP
rs1388170361 182 dbSNP
rs1360680093 190 dbSNP
rs1292531196 200 dbSNP
rs1420706305 205 dbSNP
rs376723569 207 dbSNP
rs371009456 208 dbSNP
rs1048628606 209 dbSNP
rs1201140215 210 dbSNP
rs544820422 211 dbSNP
rs937994612 213 dbSNP
rs888711594 216 dbSNP
rs1004195294 225 dbSNP
rs1488498508 232 dbSNP
rs1287980272 233 dbSNP
rs776252828 235 dbSNP
rs1352959590 236 dbSNP
rs1256485824 238 dbSNP
rs1234810627 241 dbSNP
rs1452334137 251 dbSNP
rs1300169211 258 dbSNP
rs1056418415 262 dbSNP
rs970752874 263 dbSNP
rs1003577088 268 dbSNP
rs1033764894 269 dbSNP
rs918160473 283 dbSNP
rs945623442 285 dbSNP
rs1464624381 290 dbSNP
rs959179634 310 dbSNP
rs1171475975 312 dbSNP
rs904032490 313 dbSNP
rs146077521 315 dbSNP
rs915134069 330 dbSNP
rs533674404 331 dbSNP
rs977744660 338 dbSNP
rs911553038 339 dbSNP
rs555017651 340 dbSNP
rs1038798176 350 dbSNP
rs1019331945 351 dbSNP
rs1399807831 357 dbSNP
rs961278346 358 dbSNP
rs1336725673 362 dbSNP
rs1406685098 363 dbSNP
rs1394873300 373 dbSNP
rs1402105284 376 dbSNP
rs921710133 383 dbSNP
rs527319199 386 dbSNP
rs1170166312 393 dbSNP
rs1474961695 396 dbSNP
rs1368906016 397 dbSNP
rs1435239844 401 dbSNP
rs1321782552 406 dbSNP
rs1440673907 409 dbSNP
rs1368043679 412 dbSNP
rs932779516 420 dbSNP
rs1244427763 423 dbSNP
rs1458676089 424 dbSNP
rs1026788747 425 dbSNP
rs1283911059 427 dbSNP
rs1213559307 428 dbSNP
rs1356612623 434 dbSNP
rs1286388655 438 dbSNP
rs1243043590 448 dbSNP
rs139313620 473 dbSNP
rs1332587577 480 dbSNP
rs1449121150 487 dbSNP
rs1398117499 490 dbSNP
rs1330757392 497 dbSNP
rs979982860 498 dbSNP
rs1282466530 500 dbSNP
rs888666914 504 dbSNP
rs926696461 505 dbSNP
rs1004879610 518 dbSNP
rs1471663895 520 dbSNP
rs560863597 520 dbSNP
rs1384554231 521 dbSNP
rs959482114 527 dbSNP
rs992082129 534 dbSNP
rs1037321137 535 dbSNP
rs1203195659 537 dbSNP
rs1451873454 548 dbSNP
rs1359112075 551 dbSNP
rs917924581 551 dbSNP
rs945621170 551 dbSNP
rs1043051563 553 dbSNP
rs1209499551 555 dbSNP
rs1383280045 556 dbSNP
rs1443979829 556 dbSNP
rs1249806986 557 dbSNP
rs1279087982 558 dbSNP
rs925583726 559 dbSNP
rs936823164 561 dbSNP
rs1163664728 562 dbSNP
rs537808951 563 dbSNP
rs1186770685 565 dbSNP
rs1421505924 566 dbSNP
rs879062586 568 dbSNP
rs1176166278 571 dbSNP
rs1478046893 573 dbSNP
rs759470150 574 dbSNP
rs12814340 575 dbSNP
rs1196238856 576 dbSNP
rs1490082738 577 dbSNP
rs1317120638 578 dbSNP
rs1458541083 579 dbSNP
rs1410833382 580 dbSNP
rs1457298961 584 dbSNP
rs1284129250 588 dbSNP
rs1219906368 594 dbSNP
rs1369743631 595 dbSNP
rs556188539 601 dbSNP
rs1273306190 605 dbSNP
rs867278617 608 dbSNP
rs1341349904 616 dbSNP
rs1298635884 619 dbSNP
rs906541699 619 dbSNP
rs1003523096 633 dbSNP
rs1403282915 644 dbSNP
rs1401585628 650 dbSNP
rs1358581858 654 dbSNP
rs889539170 659 dbSNP
rs775387857 660 dbSNP
rs1170281727 662 dbSNP
rs959460978 677 dbSNP
rs1334119046 689 dbSNP
rs1040696609 690 dbSNP
rs749725474 698 dbSNP
rs896826415 710 dbSNP
rs1487482062 712 dbSNP
rs1242055656 714 dbSNP
rs1211354173 715 dbSNP
rs1314458925 718 dbSNP
rs1276663319 721 dbSNP
rs994073452 730 dbSNP
rs1277987263 734 dbSNP
rs1328822143 735 dbSNP
rs1229253257 738 dbSNP
rs1010715882 741 dbSNP
rs1027298348 755 dbSNP
rs73313182 757 dbSNP
rs1199768941 758 dbSNP
rs1448739245 785 dbSNP
rs966616358 786 dbSNP
rs1468792468 787 dbSNP
rs1443908685 791 dbSNP
rs1172298403 795 dbSNP
rs144078770 798 dbSNP
rs1250612082 800 dbSNP
rs1182794322 803 dbSNP
rs911850255 808 dbSNP
rs1236203459 809 dbSNP
rs965690791 827 dbSNP
rs974421088 836 dbSNP
rs921659334 837 dbSNP
rs549566934 839 dbSNP
rs930384369 849 dbSNP
rs959415525 850 dbSNP
rs992216667 850 dbSNP
rs1228642168 856 dbSNP
rs1024953541 862 dbSNP
rs1312764112 863 dbSNP
rs984272791 873 dbSNP
rs910033612 879 dbSNP
rs940243917 880 dbSNP
rs1037671693 883 dbSNP
rs1332784441 889 dbSNP
rs1416510770 896 dbSNP
rs1353540152 897 dbSNP
rs1165983149 900 dbSNP
rs906821812 903 dbSNP
rs1306484300 912 dbSNP
rs544850784 913 dbSNP
rs1350274488 917 dbSNP
rs1410616468 918 dbSNP
rs1290480151 920 dbSNP
rs1383947504 932 dbSNP
rs192449987 932 dbSNP
rs1183457085 935 dbSNP
rs1440404250 935 dbSNP
rs1232690048 943 dbSNP
rs1266219157 945 dbSNP
rs1275357017 945 dbSNP
rs1480451761 945 dbSNP
rs1323225234 953 dbSNP
rs934822518 953 dbSNP
rs1289505899 958 dbSNP
rs1491142562 958 dbSNP
rs767808027 958 dbSNP
rs1055035046 959 dbSNP
rs1310881604 959 dbSNP
rs1389147359 959 dbSNP
rs368097239 959 dbSNP
rs771632416 959 dbSNP
rs11444199 960 dbSNP
rs1179786610 960 dbSNP
rs1382668801 960 dbSNP
rs1491484394 960 dbSNP
rs77729302 960 dbSNP
rs878949011 960 dbSNP
rs1273590984 961 dbSNP
rs1491566799 961 dbSNP
rs1193062466 962 dbSNP
rs1483277047 964 dbSNP
rs1206815356 965 dbSNP
rs978148491 965 dbSNP
rs1316366106 966 dbSNP
rs1266387158 967 dbSNP
rs1432075841 968 dbSNP
rs1199032655 970 dbSNP
rs1301548783 971 dbSNP
rs1302964348 971 dbSNP
rs1343243100 971 dbSNP
rs1378863208 972 dbSNP
rs796284080 972 dbSNP
rs1479259029 973 dbSNP
rs1167294695 974 dbSNP
rs77153785 974 dbSNP
rs79679701 975 dbSNP
rs1430848392 976 dbSNP
rs1310063046 979 dbSNP
rs1388919862 983 dbSNP
rs1378344135 989 dbSNP
rs572249872 994 dbSNP
rs925519751 995 dbSNP
rs936981259 995 dbSNP
rs543163396 1000 dbSNP
rs1055066999 1002 dbSNP
rs1263781661 1007 dbSNP
rs1203242316 1012 dbSNP
rs985589772 1013 dbSNP
rs895195429 1024 dbSNP
rs1256137245 1035 dbSNP
rs1324212896 1038 dbSNP
rs1332928872 1048 dbSNP
rs1011414354 1049 dbSNP
rs1219648601 1050 dbSNP
rs1296833140 1055 dbSNP
rs1342579161 1060 dbSNP
rs182733929 1061 dbSNP
rs1040832430 1080 dbSNP
rs1263307170 1081 dbSNP
rs896924736 1088 dbSNP
rs1428890678 1095 dbSNP
rs1468263623 1095 dbSNP
rs1171584645 1100 dbSNP
rs902340354 1107 dbSNP
rs1190742577 1114 dbSNP
rs531616548 1115 dbSNP
rs146523694 1117 dbSNP
rs999388255 1118 dbSNP
rs1018847114 1121 dbSNP
rs1459545127 1123 dbSNP
rs1210073477 1125 dbSNP
rs929618089 1127 dbSNP
rs148698267 1128 dbSNP
rs771617089 1146 dbSNP
rs974368911 1148 dbSNP
rs1315382739 1152 dbSNP
rs1001415308 1163 dbSNP
rs142212620 1165 dbSNP
rs951779584 1167 dbSNP
rs984945372 1170 dbSNP
rs1390156725 1172 dbSNP
rs772973141 1183 dbSNP
rs547667489 1189 dbSNP
rs760080757 1203 dbSNP
rs187964390 1211 dbSNP
rs530198792 1223 dbSNP
rs928195766 1224 dbSNP
rs1178689929 1228 dbSNP
rs1242051239 1228 dbSNP
rs1439232912 1235 dbSNP
rs759918752 1237 dbSNP
rs1270400451 1239 dbSNP
rs879683932 1243 dbSNP
rs767996294 1246 dbSNP
rs1195611637 1248 dbSNP
rs1357426366 1251 dbSNP
rs1433049633 1254 dbSNP
rs1025468989 1255 dbSNP
rs548679363 1257 dbSNP
rs1310143881 1261 dbSNP
rs1365920490 1268 dbSNP
rs1334222354 1270 dbSNP
rs567307738 1273 dbSNP
rs1328366506 1280 dbSNP
rs966854568 1282 dbSNP
rs537540945 1287 dbSNP
rs1055012782 1291 dbSNP
rs1032348527 1293 dbSNP
rs958240333 1297 dbSNP
rs985720701 1298 dbSNP
rs1470852621 1300 dbSNP
rs895140016 1306 dbSNP
rs556167316 1312 dbSNP
rs61921780 1313 dbSNP
rs1451821941 1318 dbSNP
rs1326439708 1331 dbSNP
rs976946833 1341 dbSNP
rs1359410987 1343 dbSNP
rs1207620342 1345 dbSNP
rs533513524 1352 dbSNP
rs1317798967 1353 dbSNP
rs765174294 1353 dbSNP
rs1191070921 1354 dbSNP
rs1437529214 1364 dbSNP
rs1347597039 1370 dbSNP
rs929781220 1375 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 3224.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions LCL-BACD1 , LCL-BACD3
Disease MIMAT0025478
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1020024. RNA binding protein: AGO2. Condition:EBV B95-8-infected "PAR-CLIP data was present in GSM1020025. RNA binding protein: AGO2. Condition:EBV B95-8-infected ...

- Skalsky RL; Corcoran DL; Gottwein E; Frank et al., 2012, PLoS pathogens.

Article - Skalsky RL; Corcoran DL; Gottwein E; Frank et al.
- PLoS pathogens, 2012
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role in viral oncogenesis. To date, only a limited number of EBV miRNA targets have been identified; thus, the role of EBV miRNAs in viral pathogenesis and/or lymphomagenesis is not well defined. Here, we used photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) combined with deep sequencing and computational analysis to comprehensively examine the viral and cellular miRNA targetome in EBV strain B95-8-infected lymphoblastoid cell lines (LCLs). We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs. 24 PAR-CLIP-identified miRNA:3'UTR interactions were confirmed by reporter assays. Our results reveal that EBV miRNAs predominantly target cellular transcripts during latent infection, thereby manipulating the host environment. Furthermore, targets of EBV miRNAs are involved in multiple cellular processes that are directly relevant to viral infection, including innate immunity, cell survival, and cell proliferation. Finally, we present evidence that myc-regulated host miRNAs from the miR-17/92 cluster can regulate latent viral gene expression. This comprehensive survey of the miRNA targetome in EBV-infected B cells represents a key step towards defining the functions of EBV-encoded miRNAs, and potentially, identifying novel therapeutic targets for EBV-associated malignancies.
LinkOut: [PMID: 22291592]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 3224.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065670. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000040584.4 | 3UTR | UUUGUUGCUGCUUAUUUCACUAAGAAAACCCAACAACUGAGACUGCCUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000040584.4 | 3UTR | AAAACCCAACAACUGAGACUGCCUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1065670
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / 4-thiouridine, 3_ML_LG
Location of target site ENST00000040584.4 | 3UTR | AAAACCCAACAACUGAGACUGCCUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM1020024
Method / RBP PAR-CLIP / AGO2
Cell line / Condition LCL-BACD1 / EBV B95-8-infected, 4-thiouridine, RNase T1
Location of target site ENST00000040584.4 | 3UTR | GCCUAGCCCGCCGGUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22291592 / GSE41437
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM1020025
Method / RBP PAR-CLIP / AGO2
Cell line / Condition LCL-BACD3 / EBV B95-8-infected, 4-thiouridine, RNase T1
Location of target site ENST00000040584.4 | 3UTR | GCCUAGCCCGCCGGUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22291592 / GSE41437
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
303 hsa-miR-6511a-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT061598 BTG2 BTG anti-proliferation factor 2 2 2
MIRT065800 HOXC8 homeobox C8 2 6
MIRT070739 HIF1A hypoxia inducible factor 1 alpha subunit 2 2
MIRT073283 IREB2 iron responsive element binding protein 2 2 2
MIRT079374 CCDC137 coiled-coil domain containing 137 2 2
MIRT088059 UBXN2A UBX domain protein 2A 2 4
MIRT145629 LASP1 LIM and SH3 protein 1 2 2
MIRT152258 ZNF460 zinc finger protein 460 2 8
MIRT192135 PAPOLA poly(A) polymerase alpha 2 2
MIRT197663 DHX40 DEAH-box helicase 40 2 2
MIRT224280 FAM91A1 family with sequence similarity 91 member A1 2 4
MIRT246475 ZBTB7B zinc finger and BTB domain containing 7B 2 2
MIRT246680 UHMK1 U2AF homology motif kinase 1 2 2
MIRT254106 PLEKHB2 pleckstrin homology domain containing B2 2 2
MIRT282637 IGF1R insulin like growth factor 1 receptor 2 4
MIRT307058 TGFBR2 transforming growth factor beta receptor 2 2 2
MIRT310365 PDGFRA platelet derived growth factor receptor alpha 2 4
MIRT317937 SLC29A1 solute carrier family 29 member 1 (Augustine blood group) 2 2
MIRT353111 PIM3 Pim-3 proto-oncogene, serine/threonine kinase 2 2
MIRT370516 ZNRF3 zinc and ring finger 3 2 2
MIRT377075 SLC35F6 solute carrier family 35 member F6 2 2
MIRT395058 TNFAIP2 TNF alpha induced protein 2 2 2
MIRT443679 HSD17B12 hydroxysteroid 17-beta dehydrogenase 12 2 6
MIRT446960 ZNF431 zinc finger protein 431 2 2
MIRT447172 MFSD8 major facilitator superfamily domain containing 8 2 2
MIRT449417 TMEM106B transmembrane protein 106B 2 2
MIRT451118 RPS19 ribosomal protein S19 2 2
MIRT451352 ZNF573 zinc finger protein 573 2 4
MIRT451984 FKBP5 FK506 binding protein 5 2 2
MIRT452225 HAVCR1 hepatitis A virus cellular receptor 1 2 8
MIRT452288 CARD8 caspase recruitment domain family member 8 2 2
MIRT452348 TG thyroglobulin 2 2
MIRT452402 TTC39B tetratricopeptide repeat domain 39B 2 2
MIRT452521 TFDP2 transcription factor Dp-2 2 6
MIRT452900 PSD4 pleckstrin and Sec7 domain containing 4 2 4
MIRT453032 ZNF527 zinc finger protein 527 2 4
MIRT453177 CNOT4 CCR4-NOT transcription complex subunit 4 2 6
MIRT453203 ZNF589 zinc finger protein 589 2 4
MIRT453319 ZNF394 zinc finger protein 394 2 2
MIRT453568 RDH13 retinol dehydrogenase 13 2 2
MIRT453917 GABRR2 gamma-aminobutyric acid type A receptor rho2 subunit 2 4
MIRT453931 COMMD5 COMM domain containing 5 2 4
MIRT454103 TMEM209 transmembrane protein 209 2 2
MIRT454410 AKAP5 A-kinase anchoring protein 5 2 2
MIRT454578 NT5DC3 5'-nucleotidase domain containing 3 2 2
MIRT455490 NPY4R neuropeptide Y receptor Y4 2 2
MIRT455694 GLO1 glyoxalase I 2 2
MIRT455798 TAF8 TATA-box binding protein associated factor 8 2 2
MIRT455813 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT455939 SURF6 surfeit 6 2 2
MIRT456667 TIFA TRAF interacting protein with forkhead associated domain 2 2
MIRT456807 SIGLEC14 sialic acid binding Ig like lectin 14 2 2
MIRT457006 ZNF669 zinc finger protein 669 2 2
MIRT457090 XPNPEP3 X-prolyl aminopeptidase 3 2 2
MIRT457124 APOLD1 apolipoprotein L domain containing 1 2 2
MIRT457324 DUSP19 dual specificity phosphatase 19 2 4
MIRT457554 ZC3H6 zinc finger CCCH-type containing 6 2 2
MIRT457646 ZNF69 zinc finger protein 69 2 2
MIRT458090 C8orf33 chromosome 8 open reading frame 33 2 2
MIRT458145 TLCD2 TLC domain containing 2 2 2
MIRT458162 LYRM4 LYR motif containing 4 2 6
MIRT458198 ATP6V0A2 ATPase H+ transporting V0 subunit a2 2 2
MIRT458565 C10orf71 chromosome 10 open reading frame 71 2 2
MIRT458624 TRIM72 tripartite motif containing 72 2 4
MIRT458655 SGPP2 sphingosine-1-phosphate phosphatase 2 2 2
MIRT458806 CYP8B1 cytochrome P450 family 8 subfamily B member 1 2 2
MIRT458903 PFAS phosphoribosylformylglycinamidine synthase 2 6
MIRT459043 ZNF490 zinc finger protein 490 2 4
MIRT459136 FADS6 fatty acid desaturase 6 2 2
MIRT459157 NARF nuclear prelamin A recognition factor 2 4
MIRT459185 HSPA6 heat shock protein family A (Hsp70) member 6 2 4
MIRT459375 MPLKIP M-phase specific PLK1 interacting protein 2 6
MIRT459432 FAM83B family with sequence similarity 83 member B 2 2
MIRT459763 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT459862 SVOP SV2 related protein 2 8
MIRT460048 CDCP1 CUB domain containing protein 1 2 4
MIRT460240 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT460253 IL17RB interleukin 17 receptor B 2 4
MIRT460388 GUF1 GUF1 homolog, GTPase 2 4
MIRT460521 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT460984 STK17B serine/threonine kinase 17b 2 2
MIRT461050 DCPS decapping enzyme, scavenger 2 4
MIRT461145 ZNF264 zinc finger protein 264 2 2
MIRT461216 TIPIN TIMELESS interacting protein 2 2
MIRT461409 SLFN12L schlafen family member 12 like 2 10
MIRT461422 CTSL2 cathepsin V 1 1
MIRT461446 ACSBG1 acyl-CoA synthetase bubblegum family member 1 2 2
MIRT461513 NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 2 2
MIRT461871 ZNF317 zinc finger protein 317 2 2
MIRT461898 NECAB3 N-terminal EF-hand calcium binding protein 3 2 2
MIRT462228 NUP155 nucleoporin 155 2 4
MIRT462495 GSR glutathione-disulfide reductase 2 2
MIRT462530 DHODH dihydroorotate dehydrogenase (quinone) 2 6
MIRT462622 C20orf27 chromosome 20 open reading frame 27 2 4
MIRT462867 CYP51A1 cytochrome P450 family 51 subfamily A member 1 2 2
MIRT463024 ZNF70 zinc finger protein 70 2 2
MIRT463047 ZNF689 zinc finger protein 689 2 2
MIRT463080 ZNF639 zinc finger protein 639 2 2
MIRT463131 ZNF451 zinc finger protein 451 2 4
MIRT463364 ZFAND4 zinc finger AN1-type containing 4 2 2
MIRT463822 XKR4 XK related 4 2 2
MIRT464362 USP12P1 ubiquitin specific peptidase 12 pseudogene 1 2 2
MIRT464450 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT464537 UBTF upstream binding transcription factor, RNA polymerase I 2 2
MIRT464771 UBE2G1 ubiquitin conjugating enzyme E2 G1 2 2
MIRT465332 TPM3 tropomyosin 3 2 2
MIRT465533 PRICKLE4 prickle planar cell polarity protein 4 2 2
MIRT466098 TMEM184C transmembrane protein 184C 2 2
MIRT467092 SRRD SRR1 domain containing 2 2
MIRT467262 SPPL2A signal peptide peptidase like 2A 2 2
MIRT467545 SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 2 2
MIRT468585 SERBP1 SERPINE1 mRNA binding protein 1 2 6
MIRT469039 RNF38 ring finger protein 38 2 6
MIRT469688 RAB5B RAB5B, member RAS oncogene family 2 2
MIRT469968 PTPRF protein tyrosine phosphatase, receptor type F 2 2
MIRT470510 PPP1R11 protein phosphatase 1 regulatory inhibitor subunit 11 2 2
MIRT471145 PHF19 PHD finger protein 19 2 2
MIRT471238 PHAX phosphorylated adaptor for RNA export 2 2
MIRT471654 PANK2 pantothenate kinase 2 2 4
MIRT472112 NME2 NME/NM23 nucleoside diphosphate kinase 2 2 2
MIRT472129 NME1-NME2 NME1-NME2 readthrough 2 2
MIRT472504 NACC2 NACC family member 2 2 2
MIRT472879 MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 2
MIRT472968 MSANTD3 Myb/SANT DNA binding domain containing 3 2 2
MIRT473024 MRPS14 mitochondrial ribosomal protein S14 2 2
MIRT473085 MORN4 MORN repeat containing 4 2 2
MIRT474102 LMBR1L limb development membrane protein 1 like 2 2
MIRT474123 LIPC lipase C, hepatic type 2 2
MIRT474893 KCTD5 potassium channel tetramerization domain containing 5 2 2
MIRT475506 HSP90B1 heat shock protein 90 beta family member 1 2 4
MIRT476417 GDE1 glycerophosphodiester phosphodiesterase 1 2 8
MIRT477239 ETF1 eukaryotic translation termination factor 1 2 2
MIRT478007 DNAL1 dynein axonemal light chain 1 2 2
MIRT478306 DDX19A DEAD-box helicase 19A 2 6
MIRT478864 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT479182 CLSPN claspin 2 2
MIRT479433 CDKN1B cyclin dependent kinase inhibitor 1B 2 8
MIRT479549 CDC5L cell division cycle 5 like 2 4
MIRT479672 CCSER2 coiled-coil serine rich protein 2 2 2
MIRT479786 CCND1 cyclin D1 2 2
MIRT480737 BPTF bromodomain PHD finger transcription factor 2 6
MIRT481578 ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 2 2
MIRT481707 AR androgen receptor 2 2
MIRT482502 ACTR1A ARP1 actin related protein 1 homolog A 2 2
MIRT484908 ZFYVE26 zinc finger FYVE-type containing 26 2 4
MIRT486077 ARPP19 cAMP regulated phosphoprotein 19 2 4
MIRT487020 C2orf82 chromosome 2 open reading frame 82 2 2
MIRT487472 ANKRD42 ankyrin repeat domain 42 2 2
MIRT488741 ASGR2 asialoglycoprotein receptor 2 2 4
MIRT489516 CRLF3 cytokine receptor like factor 3 2 4
MIRT490217 SLC37A2 solute carrier family 37 member 2 2 4
MIRT494736 ARHGAP1 Rho GTPase activating protein 1 2 6
MIRT495463 PNMAL2 paraneoplastic Ma antigen family member 8B 2 2
MIRT495495 VTI1B vesicle transport through interaction with t-SNAREs 1B 2 2
MIRT495730 AGO1 argonaute 1, RISC catalytic component 2 2
MIRT495776 ZNF546 zinc finger protein 546 2 2
MIRT495808 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT495828 TMEM151A transmembrane protein 151A 2 2
MIRT496080 ATP1B4 ATPase Na+/K+ transporting family member beta 4 2 2
MIRT496104 SNX17 sorting nexin 17 2 2
MIRT496141 RBL1 RB transcriptional corepressor like 1 2 2
MIRT496183 TRIM73 tripartite motif containing 73 2 2
MIRT496237 TRIM74 tripartite motif containing 74 2 2
MIRT496266 SHROOM2 shroom family member 2 2 2
MIRT496281 SLC2A13 solute carrier family 2 member 13 2 2
MIRT496293 BAZ2A bromodomain adjacent to zinc finger domain 2A 2 2
MIRT496501 MAST3 microtubule associated serine/threonine kinase 3 2 2
MIRT496546 EBI3 Epstein-Barr virus induced 3 2 2
MIRT496929 DPYSL5 dihydropyrimidinase like 5 2 2
MIRT499164 EYA3 EYA transcriptional coactivator and phosphatase 3 2 2
MIRT499323 IGSF9 immunoglobulin superfamily member 9 2 2
MIRT500561 XBP1P1 X-box binding protein 1 pseudogene 1 2 8
MIRT502505 EVI5 ecotropic viral integration site 5 2 2
MIRT503042 CAMSAP2 calmodulin regulated spectrin associated protein family member 2 2 2
MIRT503530 ATG12 autophagy related 12 2 2
MIRT507274 FERMT2 fermitin family member 2 2 2
MIRT510472 ZDHHC18 zinc finger DHHC-type containing 18 2 2
MIRT510696 SRM spermidine synthase 2 6
MIRT512281 ARHGDIA Rho GDP dissociation inhibitor alpha 2 6
MIRT512638 CPEB3 cytoplasmic polyadenylation element binding protein 3 2 4
MIRT512727 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT512945 MAP3K7 mitogen-activated protein kinase kinase kinase 7 2 4
MIRT513150 CSDC2 cold shock domain containing C2 2 2
MIRT514488 SLPI secretory leukocyte peptidase inhibitor 2 4
MIRT516456 IFNGR1 interferon gamma receptor 1 2 6
MIRT517420 BMP8A bone morphogenetic protein 8a 2 2
MIRT527519 FAM172A family with sequence similarity 172 member A 2 2
MIRT535051 PQLC1 PQ loop repeat containing 1 2 2
MIRT542619 XIAP X-linked inhibitor of apoptosis 2 2
MIRT546544 SATB2 SATB homeobox 2 2 2
MIRT548046 GOLIM4 golgi integral membrane protein 4 2 2
MIRT550432 ORC4 origin recognition complex subunit 4 2 2
MIRT551595 HDGFRP2 HDGF like 2 2 2
MIRT551709 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT555848 PAPD7 poly(A) RNA polymerase D7, non-canonical 2 4
MIRT556805 KIAA1958 KIAA1958 2 2
MIRT557554 GOSR1 golgi SNAP receptor complex member 1 2 2
MIRT559322 ATXN1 ataxin 1 2 2
MIRT559742 ACOX1 acyl-CoA oxidase 1 2 2
MIRT559972 PARP2 poly(ADP-ribose) polymerase 2 2 2
MIRT560797 EPM2AIP1 EPM2A interacting protein 1 2 2
MIRT562837 GCFC2 GC-rich sequence DNA-binding factor 2 2 2
MIRT564055 NDUFA7 NADH:ubiquinone oxidoreductase subunit A7 2 2
MIRT564250 LLPH LLP homolog, long-term synaptic facilitation 2 2
MIRT566806 MB21D2 Mab-21 domain containing 2 2 2
MIRT570094 SCN2B sodium voltage-gated channel beta subunit 2 2 2
MIRT575233 Fut1 fucosyltransferase 1 2 2
MIRT576653 Mill2 MHC I like leukocyte 2 1 1
MIRT609259 XRCC3 X-ray repair cross complementing 3 2 2
MIRT611202 TMEM105 transmembrane protein 105 2 2
MIRT613405 DNAH17 dynein axonemal heavy chain 17 2 2
MIRT614314 C9orf62 chromosome 9 open reading frame 62 2 2
MIRT614378 AMZ1 archaelysin family metallopeptidase 1 2 2
MIRT614483 FRMPD3 FERM and PDZ domain containing 3 2 2
MIRT614603 IRF2BPL interferon regulatory factor 2 binding protein like 2 2
MIRT618743 KIF1B kinesin family member 1B 2 2
MIRT628410 BSN bassoon presynaptic cytomatrix protein 2 2
MIRT630340 PAQR5 progestin and adipoQ receptor family member 5 2 2
MIRT632737 MLLT6 MLLT6, PHD finger containing 2 2
MIRT633734 BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 2 2
MIRT636056 ZSCAN29 zinc finger and SCAN domain containing 29 2 4
MIRT638836 CRTAP cartilage associated protein 2 2
MIRT643909 TCEB2 elongin B 2 2
MIRT649313 IGSF6 immunoglobulin superfamily member 6 2 2
MIRT655027 PLA2G16 phospholipase A2 group XVI 2 4
MIRT661320 CPM carboxypeptidase M 2 2
MIRT662143 ZC3H8 zinc finger CCCH-type containing 8 2 2
MIRT663248 MPHOSPH8 M-phase phosphoprotein 8 2 4
MIRT664303 HINT1 histidine triad nucleotide binding protein 1 2 2
MIRT665042 SLC35E2 solute carrier family 35 member E2 2 2
MIRT667992 HECTD3 HECT domain E3 ubiquitin protein ligase 3 2 2
MIRT668465 FAM208A family with sequence similarity 208 member A 2 2
MIRT671593 KLHL21 kelch like family member 21 2 2
MIRT675366 KLHL26 kelch like family member 26 2 2
MIRT677448 PDE11A phosphodiesterase 11A 2 2
MIRT680620 KIAA0391 KIAA0391 2 2
MIRT680654 KIAA1456 KIAA1456 2 2
MIRT680721 PCCB propionyl-CoA carboxylase beta subunit 2 2
MIRT680735 PRICKLE1 prickle planar cell polarity protein 1 2 2
MIRT680890 MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1 like 2 2
MIRT680911 SCN3B sodium voltage-gated channel beta subunit 3 2 2
MIRT681019 AAED1 AhpC/TSA antioxidant enzyme domain containing 1 2 2
MIRT681180 IBA57 IBA57 homolog, iron-sulfur cluster assembly 2 2
MIRT681252 ZNF383 zinc finger protein 383 2 2
MIRT681379 VHLL VHL like 2 2
MIRT681454 CIITA class II major histocompatibility complex transactivator 2 2
MIRT681628 F2RL2 coagulation factor II thrombin receptor like 2 2 2
MIRT681646 SCRG1 stimulator of chondrogenesis 1 2 2
MIRT681680 COX18 COX18, cytochrome c oxidase assembly factor 2 2
MIRT681928 KAT7 lysine acetyltransferase 7 2 2
MIRT681969 TFCP2 transcription factor CP2 2 2
MIRT681993 HRH4 histamine receptor H4 2 2
MIRT682012 ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B) 2 2
MIRT682018 GNAT1 G protein subunit alpha transducin 1 2 2
MIRT682052 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT682128 THBS1 thrombospondin 1 2 2
MIRT682159 SMS spermine synthase 2 2
MIRT682204 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT682430 NRXN3 neurexin 3 2 2
MIRT682470 MCUR1 mitochondrial calcium uniporter regulator 1 2 2
MIRT682497 KATNAL1 katanin catalytic subunit A1 like 1 2 2
MIRT682556 EXOSC2 exosome component 2 2 2
MIRT683775 CPE carboxypeptidase E 2 2
MIRT686015 NEK4 NIMA related kinase 4 2 2
MIRT686079 PTK6 protein tyrosine kinase 6 2 2
MIRT687341 OSBPL2 oxysterol binding protein like 2 2 2
MIRT687763 KIAA1328 KIAA1328 2 2
MIRT688090 GLUL glutamate-ammonia ligase 2 2
MIRT688794 CCNB1 cyclin B1 2 2
MIRT688963 ATXN3 ataxin 3 2 2
MIRT689388 ZNF850 zinc finger protein 850 2 2
MIRT689415 UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 2 2
MIRT689502 SCARF1 scavenger receptor class F member 1 2 2
MIRT690555 GNG4 G protein subunit gamma 4 2 2
MIRT690677 RPF2 ribosome production factor 2 homolog 2 2
MIRT691144 HJURP Holliday junction recognition protein 2 2
MIRT691200 NIF3L1 NGG1 interacting factor 3 like 1 2 2
MIRT691561 OR51E2 olfactory receptor family 51 subfamily E member 2 2 2
MIRT691984 PLCXD1 phosphatidylinositol specific phospholipase C X domain containing 1 2 2
MIRT693580 PIGR polymeric immunoglobulin receptor 2 2
MIRT693804 RHOG ras homolog family member G 2 2
MIRT694026 PPIL4 peptidylprolyl isomerase like 4 2 2
MIRT694244 ZNF749 zinc finger protein 749 2 2
MIRT694712 CD300LG CD300 molecule like family member g 2 2
MIRT695696 ATP6V0D2 ATPase H+ transporting V0 subunit d2 2 2
MIRT695744 ZNF117 zinc finger protein 117 2 2
MIRT696388 SLC27A1 solute carrier family 27 member 1 2 2
MIRT696665 AGXT2 alanine--glyoxylate aminotransferase 2 2 2
MIRT697003 CCDC80 coiled-coil domain containing 80 2 2
MIRT697016 HAUS5 HAUS augmin like complex subunit 5 2 2
MIRT697140 B4GALT7 beta-1,4-galactosyltransferase 7 2 2
MIRT698238 TMEM216 transmembrane protein 216 2 2
MIRT699506 SKIL SKI like proto-oncogene 2 2
MIRT700423 QDPR quinoid dihydropteridine reductase 2 2
MIRT700529 PTPLB 3-hydroxyacyl-CoA dehydratase 2 1 1
MIRT700729 PNO1 partner of NOB1 homolog 2 2
MIRT702838 HOOK3 hook microtubule tethering protein 3 2 2
MIRT703452 FYTTD1 forty-two-three domain containing 1 2 2
MIRT706157 ZNF674 zinc finger protein 674 2 2
MIRT706183 ZNF716 zinc finger protein 716 2 2
MIRT706484 SNX27 sorting nexin family member 27 2 2
MIRT714457 PTDSS2 phosphatidylserine synthase 2 2 2
MIRT720295 DLGAP3 DLG associated protein 3 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-6511a-5p Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-6511a-5p Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-miR-6511a-5p Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-6511a-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (MGC-803)

Error report submission