miRTarBase - #MIRT066489


—
pre-miRNA Information
pre-miRNA hsa-mir-4500   
Genomic Coordinates chr13: 87618665 - 87618740
Description Homo sapiens miR-4500 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4500
Sequence 54| UGAGGUAGUAGUUUCUU |70
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1322800324 2 dbSNP
rs1401270256 3 dbSNP
rs1382127193 7 dbSNP
rs1156555764 9 dbSNP
rs1438864054 10 dbSNP
rs1379842540 13 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol HMGA2   
Synonyms BABL, HMGI-C, HMGIC, LIPO, STQTL9
Description high mobility group AT-hook 2
Transcript NM_003483   
Other Transcripts NM_003484   
Expression
Putative miRNA Targets on HMGA2
3'UTR of HMGA2
(miRNA target sites are highlighted)		 
>HMGA2|NM_003483|3'UTR
   1 GGGGCGCCAACGTTCGATTTCTACCTCAGCAGCAGTTGGATCTTTTGAAGGGAGAAGACACTGCAGTGACCACTTATTCT
  81 GTATTGCCATGGTCTTTCCACTTTCATCTGGGGTGGGGTGGGGTGGGGTGGGGGAGGGGGGGGTGGGGTGGGGAGAAATC
 161 ACATAACCTTAAAAAGGACTATATTAATCACCTTCTTTGTAATCCCTTCACAGTCCCAGGTTTAGTGAAAAACTGCTGTA
 241 AACACAGGGGACACAGCTTAACAATGCAACTTTTAATTACTGTTTTCTTTTTTCTTAACCTACTAATAGTTTGTTGATCT
 321 GATAAGCAAGAGTGGGCGGGTGAGAAAAACCGAATTGGGTTTAGTCAATCACTGCACTGCATGCAAACAAGAAACGTGTC
 401 ACACTTGTGACGTCGGGCATTCATATAGGAAGAACGCGGTGTGTAACACTGTGTACACCTCAAATACCACCCCAACCCAC
 481 TCCCTGTAGTGAATCCTCTGTTTAGAACACCAAAGATAAGGACTAGATACTACTTTCTCTTTTTCGTATAATCTTGTAGA
 561 CACTTACTTGATGATTTTTAACTTTTTATTTCTAAATGAGACGAAATGCTGATGTATCCTTTCATTCAGCTAACAAACTA
 641 GAAAAGGTTATGTTCATTTTTCAAAAAGGGAAGTAAGCAAACAAATATTGCCAACTCTTCTATTTATGGATATCACACAT
 721 ATCAGCAGGAGTAATAAATTTACTCACAGCACTTGTTTTCAGGACAACACTTCATTTTCAGGAAATCTACTTCCTACAGA
 801 GCCAAAATGCCATTTAGCAATAAATAACACTTGTCAGCCTCAGAGCATTTAAGGAAACTAGACAAGTAAAATTATCCTCT
 881 TTGTAATTTAATGAAAAGGTACAACAGAATAATGCATGATGAACTCACCTAATTATGAGGTGGGAGGAGCGAAATCTAAA
 961 TTTCTTTTGCTATAGTTATACATCAATTTAAAAAGCAAAAAAAAAAAAGGGGGGGGCAATCTCTCTCTGTGTCTTTCTCT
1041 CTCTCTCTTCCTCTCCCTCTCTCTTTTCATTGTGTATCAGTTTCCATGAAAGACCTGAATACCACTTACCTCAAATTAAG
1121 CATATGTGTTACTTCAAGTAATACGTTTTGACATAAGATGGTTGACCAAGGTGCTTTTCTTCGGCTTGAGTTCACCATCT
1201 CTTCATTCAAACTGCACTTTTAGCCAGAGATGCAATATATCCCCACTACTCAATACTACCTCTGAATGTTACAACGAATT
1281 TACAGTCTAGTACTTATTACATGCTGCTATACACAAGCAATGCAAGAAAAAAACTTACTGGGTAGGTGATTCTAATCATC
1361 TGCAGTTCTTTTTGTACACTTAATTACAGTTAAAGAAGCAATCTCCTTACTGTGTTTCAGCATGACTATGTATTTTTCTA
1441 TGTTTTTTTAATTAAAAATTTTTAAAATACTTGTTTCAGCTTCTCTGCTAGATTTCTACATTAACTTGAAAATTTTTTAA
1521 CCAAGTCGCTCCTAGGTTCTTAAGGATAATTTTCCTCAATCACACTACACATCACACAAGATTTGACTGTAATATTTAAA
1601 TATTACCCTCCAAGTCTGTACCTCAAATGAATTCTTTAAGGAGATGGACTAATTGACTTGCAAAGACCTACCTCCAGACT
1681 TCAAAAGGAATGAACTTGTTACTTGCAGCATTCATTTGTTTTTTCAATGTTTGAAATAGTTCAAACTGCAGCTAACCCTA
1761 GTCAAAACTATTTTTGTAAAAGACATTTGATAGAAAGGAACACGTTTTTACATACTTTTGCAAAATAAGTAAATAATAAA
1841 TAAAATAAAAGCCAACCTTCAAAGAAACTTGAAGCTTTGTAGGTGAGATGCAACAAGCCCTGCTTTTGCATAATGCAATC
1921 AAAAATATGTGTTTTTAAGATTAGTTGAATATAAGAAAATGCTTGACAAATATTTTCATGTATTTTACACAAATGTGATT
2001 TTTGTAATATGTCTCAACCAGATTTATTTTAAACGCTTCTTATGTAGAGTTTTTATGCCTTTCTCTCCTAGTGAGTGTGC
2081 TGACTTTTTAACATGGTATTATCAACTGGGCCAGGAGGTAGTTTCTCATGACGGCTTTTGTCAGTATGGCTTTTAGTACT
2161 GAAGCCAAATGAAACTCAAAACCATCTCTCTTCCAGCTGCTTCAGGGAGGTAGTTTCAAAGGCCACATACCTCTCTGAGA
2241 CTGGCAGATCGCTCACTGTTGTGAATCACCAAAGGAGCTATGGAGAGAATTAAAACTCAACATTACTGTTAACTGTGCGT
2321 TAAATAAGCAAATAAACAGTGGCTCATAAAAATAAAAGTCGCATTCCATATCTTTGGATGGGCCTTTTAGAAACCTCATT
2401 GGCCAGCTCATAAAATGGAAGCAATTGCTCATGTTGGCCAAACATGGTGCACCGAGTGATTTCCATCTCTGGTAAAGTTA
2481 CACTTTTATTTCCTGTATGTTGTACAATCAAAACACACTACTACCTCTTAAGTCCCAGTATACCTCATTTTTCATACTGA
2561 AAAAAAAAGCTTGTGGCCAATGGAACAGTAAGAACATCATAAAATTTTTATATATATAGTTTATTTTTGTGGGAGATAAA
2641 TTTTATAGGACTGTTCTTTGCTGTTGTTGGTCGCAGCTACATAAGACTGGACATTTAACTTTTCTACCATTTCTGCAAGT
2721 TAGGTATGTTTGCAGGAGAAAAGTATCAAGACGTTTAACTGCAGTTGACTTTCTCCCTGTTCCTTTGAGTGTCTTCTAAC
2801 TTTATTCTTTGTTCTTTATGTAGAATTGCTGTCTATGATTGTACTTTGAATCGCTTGCTTGTTGAAAATATTTCTCTAGT
2881 GTATTATCACTGTCTGTTCTGCACAATAAACATAACAGCCTCTGTGATCCCCATGTGTTTTGATTCCTGCTCTTTGTTAC
2961 AGTTCCATTAAATGAGTAATAAAGTTTGGTCAAAACAGAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uucUUUGAUGAUGGAGu 5'
             | ||||||||||| 
Target 5' aacACACTACTACCTCt 3'
 2512 - 2528 162.00 -16.40
2 
miRNA  3' uucuuUGAUGAUGGAGu 5'
               | ||||||||| 
Target 5' tactcAATACTACCTCt 3'
 1247 - 1263 152.00 -12.30
3 
miRNA  3' uucuUUGAUGAUGGAGu 5'
              :|:| ||||||| 
Target 5' gttcGATTTCTACCTCa 3'
 12 - 28 149.00 -12.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM1242348 1 COSMIC
COSN30498980 6 COSMIC
COSN31596349 11 COSMIC
COSN30474072 17 COSMIC
COSN32053014 48 COSMIC
COSN30491708 52 COSMIC
COSN30534211 55 COSMIC
COSN8586555 59 COSMIC
COSN31576754 60 COSMIC
COSN31580488 80 COSMIC
COSN31614160 88 COSMIC
COSN31519445 95 COSMIC
COSN30101185 120 COSMIC
COSN30544403 257 COSMIC
COSN31487560 353 COSMIC
COSN31518960 375 COSMIC
COSN30539738 436 COSMIC
COSN21723481 538 COSMIC
COSN31519727 546 COSMIC
COSN1581244 586 COSMIC
COSN5326035 687 COSMIC
COSN17038425 825 COSMIC
COSN5950066 863 COSMIC
COSN27212563 1009 COSMIC
COSN8586556 1010 COSMIC
COSN1150951 1036 COSMIC
COSN30166699 1048 COSMIC
COSN20109788 1049 COSMIC
COSN26670430 1056 COSMIC
COSN26584325 1064 COSMIC
COSN26679429 1075 COSMIC
COSN30538239 1121 COSMIC
COSN31572636 1183 COSMIC
COSN31609326 1209 COSMIC
COSN26679430 1233 COSMIC
COSN28657680 1276 COSMIC
COSN19052666 1334 COSMIC
COSN31515725 1461 COSMIC
COSN30541930 1484 COSMIC
COSN26638373 1546 COSMIC
COSN31568588 1553 COSMIC
COSN24304566 1630 COSMIC
COSN31529638 1635 COSMIC
COSN7618365 1647 COSMIC
COSN29985168 1696 COSMIC
COSN9568130 1699 COSMIC
COSN5950067 1843 COSMIC
COSN31520008 1859 COSMIC
COSN27143837 1940 COSMIC
COSN30169882 1984 COSMIC
COSN26586650 2074 COSMIC
COSN31516604 2178 COSMIC
COSN31577346 2211 COSMIC
COSN29570602 2213 COSMIC
COSN26634875 2383 COSMIC
COSN31523268 2481 COSMIC
COSN25350982 2489 COSMIC
COSN30542496 2562 COSMIC
COSN30543041 2563 COSMIC
COSN30542027 2569 COSMIC
COSN21857329 2584 COSMIC
COSN31530470 2607 COSMIC
COSN31584727 2643 COSMIC
COSN31562847 2675 COSMIC
COSN31544871 2678 COSMIC
COSN25345985 2684 COSMIC
COSN25350983 2707 COSMIC
COSN31609312 2875 COSMIC
COSN26564959 2880 COSMIC
rs1042725 1276 GWAS
rs8756 2681 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs772000269 2 dbSNP
rs200916173 3 dbSNP
rs1221978454 4 dbSNP
rs374602952 5 dbSNP
rs1043157437 6 dbSNP
rs1179375258 7 dbSNP
rs1173016277 10 dbSNP
rs768594093 16 dbSNP
rs377439189 17 dbSNP
rs1164945515 26 dbSNP
rs199886793 35 dbSNP
rs1210955843 41 dbSNP
rs750164743 43 dbSNP
rs936462782 52 dbSNP
rs1052803161 61 dbSNP
rs1294248321 64 dbSNP
rs1490995808 65 dbSNP
rs1293296076 78 dbSNP
rs750986770 86 dbSNP
rs1243081946 91 dbSNP
rs1358110468 93 dbSNP
rs1229228760 109 dbSNP
rs1270355040 109 dbSNP
rs1324459854 109 dbSNP
rs892407845 111 dbSNP
rs1013909148 114 dbSNP
rs1199332473 115 dbSNP
rs1367312438 115 dbSNP
rs200298444 115 dbSNP
rs1237580526 120 dbSNP
rs1424026459 120 dbSNP
rs1397324838 122 dbSNP
rs1046098687 123 dbSNP
rs1457264980 125 dbSNP
rs1013205128 130 dbSNP
rs1372836563 133 dbSNP
rs1200663198 134 dbSNP
rs1215859153 135 dbSNP
rs1481640563 135 dbSNP
rs1222417780 136 dbSNP
rs1255913479 136 dbSNP
rs3837433 136 dbSNP
rs865882164 136 dbSNP
rs1197144131 137 dbSNP
rs1337093891 138 dbSNP
rs949829862 139 dbSNP
rs3741427 140 dbSNP
rs1487082728 142 dbSNP
rs1192699121 143 dbSNP
rs1257889785 144 dbSNP
rs868367967 145 dbSNP
rs1180108998 149 dbSNP
rs1031819825 150 dbSNP
rs1408407439 150 dbSNP
rs530463861 155 dbSNP
rs1035966279 167 dbSNP
rs904855329 173 dbSNP
rs1471126394 178 dbSNP
rs1001912620 180 dbSNP
rs1427708833 180 dbSNP
rs1199323021 182 dbSNP
rs1470819978 188 dbSNP
rs1160499786 192 dbSNP
rs1183283374 197 dbSNP
rs1435599176 203 dbSNP
rs550106211 204 dbSNP
rs897527374 207 dbSNP
rs1325408834 208 dbSNP
rs995487986 215 dbSNP
rs183701788 216 dbSNP
rs377007807 237 dbSNP
rs1222792753 246 dbSNP
rs1015933772 251 dbSNP
rs1419274815 259 dbSNP
rs1440025871 260 dbSNP
rs889367804 265 dbSNP
rs1337621223 267 dbSNP
rs1454844921 268 dbSNP
rs1404319159 279 dbSNP
rs866969942 300 dbSNP
rs538871482 305 dbSNP
rs1019137099 317 dbSNP
rs966105367 321 dbSNP
rs963525673 330 dbSNP
rs1342707568 331 dbSNP
rs1468108228 338 dbSNP
rs552672509 339 dbSNP
rs3741428 340 dbSNP
rs1183821746 341 dbSNP
rs988248292 348 dbSNP
rs534995821 351 dbSNP
rs1317333128 356 dbSNP
rs1026879561 357 dbSNP
rs979851883 360 dbSNP
rs925854720 383 dbSNP
rs955011122 384 dbSNP
rs1240284796 385 dbSNP
rs1315870549 396 dbSNP
rs1248413501 403 dbSNP
rs991255454 408 dbSNP
rs1336354417 409 dbSNP
rs1287482116 412 dbSNP
rs1351067478 413 dbSNP
rs1347333497 417 dbSNP
rs917102618 419 dbSNP
rs1379123855 423 dbSNP
rs988118860 423 dbSNP
rs910590615 433 dbSNP
rs543741442 436 dbSNP
rs1207730238 437 dbSNP
rs771341762 438 dbSNP
rs1470447895 439 dbSNP
rs1213517947 446 dbSNP
rs1487947831 448 dbSNP
rs756421016 457 dbSNP
rs1292433017 459 dbSNP
rs949799071 463 dbSNP
rs1357372622 467 dbSNP
rs1312211648 468 dbSNP
rs1215441854 469 dbSNP
rs555038399 478 dbSNP
rs34236173 482 dbSNP
rs1439162863 484 dbSNP
rs926006222 485 dbSNP
rs766831309 490 dbSNP
rs188200042 495 dbSNP
rs919007284 501 dbSNP
rs1366682785 504 dbSNP
rs1413164065 509 dbSNP
rs1425935987 513 dbSNP
rs1052308173 515 dbSNP
rs913718521 525 dbSNP
rs1421361074 530 dbSNP
rs949370829 535 dbSNP
rs1184505100 539 dbSNP
rs1477389317 540 dbSNP
rs75843835 545 dbSNP
rs930285842 547 dbSNP
rs879597401 549 dbSNP
rs1310813931 551 dbSNP
rs904877175 553 dbSNP
rs1489877117 565 dbSNP
rs1265009901 572 dbSNP
rs1374099377 583 dbSNP
rs1001796330 586 dbSNP
rs1466791597 587 dbSNP
rs1037431421 604 dbSNP
rs1271175194 608 dbSNP
rs1218363386 626 dbSNP
rs1346546252 633 dbSNP
rs898940921 645 dbSNP
rs537303655 647 dbSNP
rs1285734358 651 dbSNP
rs993639397 658 dbSNP
rs1275119529 670 dbSNP
rs1364835810 689 dbSNP
rs1232914628 694 dbSNP
rs1292485061 695 dbSNP
rs1026515589 697 dbSNP
rs1355876255 698 dbSNP
rs1167879815 700 dbSNP
rs556984212 705 dbSNP
rs1346646999 708 dbSNP
rs889344489 711 dbSNP
rs576933517 716 dbSNP
rs74328684 717 dbSNP
rs1458167402 720 dbSNP
rs559000036 723 dbSNP
rs1266739450 724 dbSNP
rs17847167 730 dbSNP
rs1018237594 732 dbSNP
rs1236275307 755 dbSNP
rs964727549 787 dbSNP
rs978784350 788 dbSNP
rs1009648462 790 dbSNP
rs1033000029 790 dbSNP
rs1379625405 794 dbSNP
rs1222197278 797 dbSNP
rs956144407 800 dbSNP
rs191471976 808 dbSNP
rs1312073182 812 dbSNP
rs1705 813 dbSNP
rs17847168 816 dbSNP
rs773974364 818 dbSNP
rs140646931 821 dbSNP
rs1445671464 846 dbSNP
rs1420588866 847 dbSNP
rs949208410 855 dbSNP
rs1406505862 859 dbSNP
rs1178386942 860 dbSNP
rs1464377394 867 dbSNP
rs1467504765 872 dbSNP
rs80299335 875 dbSNP
rs561394379 895 dbSNP
rs1424977926 904 dbSNP
rs34288246 928 dbSNP
rs1400177080 929 dbSNP
rs1445452586 930 dbSNP
rs1420900297 949 dbSNP
rs1248590172 950 dbSNP
rs926517939 951 dbSNP
rs1461971281 952 dbSNP
rs1245219878 954 dbSNP
rs1202124760 965 dbSNP
rs958628680 966 dbSNP
rs937911233 970 dbSNP
rs1241879014 973 dbSNP
rs1318195803 976 dbSNP
rs1332482708 985 dbSNP
rs1306507710 986 dbSNP
rs1230539903 990 dbSNP
rs145822537 992 dbSNP
rs1383004920 995 dbSNP
rs1338334298 996 dbSNP
rs1394006239 996 dbSNP
rs1170776525 997 dbSNP
rs772055044 997 dbSNP
rs796162493 997 dbSNP
rs917071587 997 dbSNP
rs1445344314 999 dbSNP
rs1318409314 1006 dbSNP
rs971169177 1007 dbSNP
rs1181992091 1008 dbSNP
rs1262949562 1008 dbSNP
rs372718814 1008 dbSNP
rs766528847 1008 dbSNP
rs1359546388 1009 dbSNP
rs1491162928 1009 dbSNP
rs77164510 1009 dbSNP
rs77692662 1010 dbSNP
rs971874249 1011 dbSNP
rs1383724822 1012 dbSNP
rs918988447 1014 dbSNP
rs1297511254 1015 dbSNP
rs1037356765 1016 dbSNP
rs1411541172 1017 dbSNP
rs1367591415 1019 dbSNP
rs1472616095 1020 dbSNP
rs898826341 1020 dbSNP
rs929108878 1021 dbSNP
rs7296768 1026 dbSNP
rs1263020911 1028 dbSNP
rs1269482854 1028 dbSNP
rs1477064592 1028 dbSNP
rs201441270 1036 dbSNP
rs563842645 1040 dbSNP
rs1198503538 1043 dbSNP
rs1264150696 1044 dbSNP
rs1048709277 1046 dbSNP
rs10573247 1048 dbSNP
rs7312910 1050 dbSNP
rs910234185 1058 dbSNP
rs552835798 1061 dbSNP
rs943599498 1070 dbSNP
rs1423581969 1071 dbSNP
rs566165063 1077 dbSNP
rs1321726611 1078 dbSNP
rs1017770073 1087 dbSNP
rs1404864630 1095 dbSNP
rs900785650 1103 dbSNP
rs149062521 1104 dbSNP
rs75519341 1105 dbSNP
rs1042969377 1110 dbSNP
rs1464342563 1120 dbSNP
rs1423429869 1126 dbSNP
rs1200781629 1127 dbSNP
rs1392175749 1133 dbSNP
rs143099265 1139 dbSNP
rs1196075552 1143 dbSNP
rs1450538574 1145 dbSNP
rs537064335 1146 dbSNP
rs988918880 1152 dbSNP
rs1315830267 1157 dbSNP
rs1024782373 1167 dbSNP
rs1224023265 1170 dbSNP
rs970604878 1174 dbSNP
rs557190608 1176 dbSNP
rs1001389397 1177 dbSNP
rs1336447660 1179 dbSNP
rs1276018975 1182 dbSNP
rs148192099 1183 dbSNP
rs926444190 1184 dbSNP
rs959397477 1186 dbSNP
rs182847557 1189 dbSNP
rs746238231 1191 dbSNP
rs937963367 1192 dbSNP
rs1172514464 1196 dbSNP
rs1477400694 1199 dbSNP
rs565798879 1202 dbSNP
rs1180088710 1207 dbSNP
rs1024135275 1208 dbSNP
rs971305239 1209 dbSNP
rs1267144569 1215 dbSNP
rs971892818 1230 dbSNP
rs920261590 1243 dbSNP
rs1026594654 1244 dbSNP
rs951810531 1245 dbSNP
rs928928906 1247 dbSNP
rs554823863 1254 dbSNP
rs984986356 1256 dbSNP
rs1281391078 1273 dbSNP
rs1042725 1276 dbSNP
rs1376382547 1277 dbSNP
rs1287055927 1284 dbSNP
rs763729121 1297 dbSNP
rs1337639705 1300 dbSNP
rs1454859316 1303 dbSNP
rs1357845329 1307 dbSNP
rs1334079662 1315 dbSNP
rs1401836140 1323 dbSNP
rs774399701 1326 dbSNP
rs1159882231 1327 dbSNP
rs1437316106 1334 dbSNP
rs1379235726 1339 dbSNP
rs1183838139 1343 dbSNP
rs1191978790 1344 dbSNP
rs1262849005 1351 dbSNP
rs879138836 1362 dbSNP
rs753665647 1363 dbSNP
rs1042726 1367 dbSNP
rs1042727 1368 dbSNP
rs942982804 1378 dbSNP
rs975750065 1382 dbSNP
rs923495786 1406 dbSNP
rs944461922 1407 dbSNP
rs1042550677 1410 dbSNP
rs1353090862 1412 dbSNP
rs541478260 1416 dbSNP
rs900671276 1417 dbSNP
rs1377390916 1420 dbSNP
rs1000452212 1426 dbSNP
rs1284022285 1430 dbSNP
rs1431957923 1431 dbSNP
rs936759030 1439 dbSNP
rs561457942 1441 dbSNP
rs1421082877 1442 dbSNP
rs751631691 1442 dbSNP
rs1013515612 1443 dbSNP
rs755710279 1443 dbSNP
rs1411334013 1450 dbSNP
rs1339674314 1457 dbSNP
rs891809363 1458 dbSNP
rs1265171434 1459 dbSNP
rs1010630526 1460 dbSNP
rs1024289924 1464 dbSNP
rs34231266 1475 dbSNP
rs1488000951 1478 dbSNP
rs1292643790 1483 dbSNP
rs1224019207 1484 dbSNP
rs1320090298 1490 dbSNP
rs1042729 1500 dbSNP
rs1342789846 1513 dbSNP
rs1244193067 1522 dbSNP
rs781344625 1528 dbSNP
rs1033511273 1529 dbSNP
rs952007056 1533 dbSNP
rs959158052 1534 dbSNP
rs1303285940 1537 dbSNP
rs543886862 1545 dbSNP
rs188169958 1546 dbSNP
rs1410306145 1552 dbSNP
rs1042730 1557 dbSNP
rs984649582 1558 dbSNP
rs950647967 1562 dbSNP
rs532730390 1569 dbSNP
rs983553048 1571 dbSNP
rs12425753 1574 dbSNP
rs1202513772 1576 dbSNP
rs142712559 1577 dbSNP
rs944495326 1578 dbSNP
rs568474503 1580 dbSNP
rs1182461484 1588 dbSNP
rs1246289081 1589 dbSNP
rs1205562529 1590 dbSNP
rs1320443331 1594 dbSNP
rs1380309080 1595 dbSNP
rs922102920 1601 dbSNP
rs1324840068 1603 dbSNP
rs1304094910 1607 dbSNP
rs922962694 1608 dbSNP
rs1364946790 1614 dbSNP
rs1292574788 1619 dbSNP
rs1447110137 1622 dbSNP
rs1402170746 1629 dbSNP
rs936126374 1635 dbSNP
rs1054731430 1646 dbSNP
rs866184973 1653 dbSNP
rs1328982065 1658 dbSNP
rs1464934865 1662 dbSNP
rs892065504 1681 dbSNP
rs1178160603 1688 dbSNP
rs1344212398 1692 dbSNP
rs978782013 1693 dbSNP
rs1177970149 1703 dbSNP
rs1010473765 1706 dbSNP
rs922627 1711 dbSNP
rs769411635 1714 dbSNP
rs1462052947 1715 dbSNP
rs1258269506 1716 dbSNP
rs370788613 1719 dbSNP
rs1231785252 1720 dbSNP
rs1395324418 1725 dbSNP
rs907198773 1728 dbSNP
rs1001574112 1740 dbSNP
rs1240267406 1752 dbSNP
rs1378604049 1758 dbSNP
rs1034360307 1760 dbSNP
rs949499486 1761 dbSNP
rs1402718663 1764 dbSNP
rs1304510421 1770 dbSNP
rs191412735 1774 dbSNP
rs994604321 1776 dbSNP
rs1046363950 1783 dbSNP
rs1441663744 1792 dbSNP
rs1378632941 1793 dbSNP
rs1178316765 1801 dbSNP
rs1027478649 1804 dbSNP
rs1235921290 1805 dbSNP
rs1254576225 1806 dbSNP
rs950728018 1822 dbSNP
rs1199219900 1827 dbSNP
rs779913418 1832 dbSNP
rs1216615152 1835 dbSNP
rs1261857814 1835 dbSNP
rs1199903745 1838 dbSNP
rs548666549 1843 dbSNP
rs993421634 1851 dbSNP
rs78295945 1857 dbSNP
rs574831732 1868 dbSNP
rs1306614443 1886 dbSNP
rs1042732 1893 dbSNP
rs1042734 1894 dbSNP
rs1042735 1896 dbSNP
rs1042736 1897 dbSNP
rs965668055 1899 dbSNP
rs1340815406 1900 dbSNP
rs974503172 1910 dbSNP
rs921658128 1921 dbSNP
rs1378303160 1928 dbSNP
rs1042737 1931 dbSNP
rs1298741349 1932 dbSNP
rs550732371 1937 dbSNP
rs147005466 1942 dbSNP
rs778231031 1946 dbSNP
rs1158238052 1950 dbSNP
rs913390492 1952 dbSNP
rs1406830032 1956 dbSNP
rs138213871 1958 dbSNP
rs1045943458 1966 dbSNP
rs1375652763 1968 dbSNP
rs1185816332 1971 dbSNP
rs997292449 1980 dbSNP
rs1030002309 1981 dbSNP
rs907203395 1984 dbSNP
rs768454241 2000 dbSNP
rs1488982157 2001 dbSNP
rs1402333069 2008 dbSNP
rs1283312607 2024 dbSNP
rs1215414541 2035 dbSNP
rs966742455 2036 dbSNP
rs1274294284 2042 dbSNP
rs1297635499 2043 dbSNP
rs187939732 2048 dbSNP
rs1388677055 2051 dbSNP
rs1401807256 2059 dbSNP
rs1055823024 2061 dbSNP
rs958326506 2070 dbSNP
rs1393063160 2073 dbSNP
rs1161691751 2081 dbSNP
rs1457708896 2104 dbSNP
rs1312042572 2106 dbSNP
rs17847170 2112 dbSNP
rs192310189 2113 dbSNP
rs1263134330 2128 dbSNP
rs1042739 2132 dbSNP
rs916771035 2133 dbSNP
rs949468984 2134 dbSNP
rs1451684768 2135 dbSNP
rs1046499133 2145 dbSNP
rs2170201 2147 dbSNP
rs995542896 2149 dbSNP
rs535284166 2165 dbSNP
rs1042740 2177 dbSNP
rs1355334692 2180 dbSNP
rs1258519853 2182 dbSNP
rs1027943156 2190 dbSNP
rs1042741 2192 dbSNP
rs1042742 2193 dbSNP
rs1315942017 2206 dbSNP
rs918679238 2208 dbSNP
rs1233984535 2214 dbSNP
rs929928613 2223 dbSNP
rs886236434 2228 dbSNP
rs1196229707 2231 dbSNP
rs1386463187 2231 dbSNP
rs761384755 2233 dbSNP
rs771765459 2239 dbSNP
rs1333732755 2246 dbSNP
rs867717325 2251 dbSNP
rs887663460 2252 dbSNP
rs1464423006 2254 dbSNP
rs1423453316 2257 dbSNP
rs185347553 2270 dbSNP
rs1480011186 2271 dbSNP
rs538795949 2273 dbSNP
rs1378896545 2276 dbSNP
rs761247117 2278 dbSNP
rs575275859 2279 dbSNP
rs1467712373 2282 dbSNP
rs900378366 2292 dbSNP
rs189879705 2303 dbSNP
rs1456286170 2314 dbSNP
rs547674457 2319 dbSNP
rs766591530 2320 dbSNP
rs1030044836 2324 dbSNP
rs1273208143 2339 dbSNP
rs1232655876 2342 dbSNP
rs181750301 2344 dbSNP
rs1311749900 2347 dbSNP
rs1444959188 2354 dbSNP
rs999567653 2356 dbSNP
rs184919666 2361 dbSNP
rs958512842 2362 dbSNP
rs1400716957 2369 dbSNP
rs1453271264 2381 dbSNP
rs374980605 2384 dbSNP
rs1180186401 2391 dbSNP
rs991070449 2400 dbSNP
rs916739881 2401 dbSNP
rs913393093 2413 dbSNP
rs535866086 2422 dbSNP
rs970836276 2423 dbSNP
rs546476844 2425 dbSNP
rs1210173201 2431 dbSNP
rs1354522882 2432 dbSNP
rs1401020447 2435 dbSNP
rs745362298 2437 dbSNP
rs982249013 2442 dbSNP
rs147193372 2446 dbSNP
rs1285098711 2448 dbSNP
rs1450670796 2449 dbSNP
rs930090923 2450 dbSNP
rs754249723 2454 dbSNP
rs1048863540 2455 dbSNP
rs1360682755 2465 dbSNP
rs34972628 2468 dbSNP
rs1160051553 2473 dbSNP
rs1321857602 2479 dbSNP
rs139284844 2487 dbSNP
rs1417535683 2496 dbSNP
rs982111645 2511 dbSNP
rs1406822919 2518 dbSNP
rs1182196238 2521 dbSNP
rs768402998 2528 dbSNP
rs1223098163 2529 dbSNP
rs78773853 2549 dbSNP
rs1263344981 2553 dbSNP
rs1473660087 2557 dbSNP
rs1187211749 2560 dbSNP
rs909910206 2560 dbSNP
rs1488658145 2571 dbSNP
rs1265482368 2573 dbSNP
rs928866387 2574 dbSNP
rs1316512962 2576 dbSNP
rs1490070608 2578 dbSNP
rs542466968 2597 dbSNP
rs941941490 2645 dbSNP
rs1039005705 2647 dbSNP
rs1293207291 2655 dbSNP
rs1401187429 2657 dbSNP
rs867632645 2661 dbSNP
rs1340573697 2663 dbSNP
rs937574122 2664 dbSNP
rs1397628349 2665 dbSNP
rs80228028 2673 dbSNP
rs1165058937 2674 dbSNP
rs8756 2681 dbSNP
rs1185920842 2682 dbSNP
rs1051608670 2691 dbSNP
rs552885609 2709 dbSNP
rs1425723700 2710 dbSNP
rs999306302 2715 dbSNP
rs1485591151 2716 dbSNP
rs1247493763 2720 dbSNP
rs763830574 2724 dbSNP
rs1224142097 2735 dbSNP
rs1162717556 2739 dbSNP
rs1273002534 2744 dbSNP
rs1219657411 2749 dbSNP
rs1032420781 2752 dbSNP
rs371955441 2753 dbSNP
rs758194543 2754 dbSNP
rs1212240065 2759 dbSNP
rs1365206384 2760 dbSNP
rs1420473286 2762 dbSNP
rs1360738169 2763 dbSNP
rs761638818 2765 dbSNP
rs1438225771 2768 dbSNP
rs1347776290 2770 dbSNP
rs1324922591 2787 dbSNP
rs1004695914 2793 dbSNP
rs893505725 2799 dbSNP
rs188648596 2808 dbSNP
rs1168515351 2832 dbSNP
rs533165764 2836 dbSNP
rs546455873 2837 dbSNP
rs868242381 2838 dbSNP
rs1430444935 2840 dbSNP
rs1426009737 2844 dbSNP
rs371770370 2853 dbSNP
rs1028701053 2854 dbSNP
rs1199593894 2858 dbSNP
rs956987343 2859 dbSNP
rs951529802 2866 dbSNP
rs984263132 2870 dbSNP
rs566451819 2871 dbSNP
rs1306385317 2872 dbSNP
rs1020001468 2875 dbSNP
rs1312212879 2880 dbSNP
rs535250837 2882 dbSNP
rs1220480249 2885 dbSNP
rs981656358 2892 dbSNP
rs1302250201 2903 dbSNP
rs199747252 2905 dbSNP
rs1402275164 2911 dbSNP
rs1287705807 2914 dbSNP
rs76032154 2916 dbSNP
rs1296346848 2923 dbSNP
rs975426736 2947 dbSNP
rs1359693993 2952 dbSNP
rs1178277310 2953 dbSNP
rs555310747 2964 dbSNP
rs867088488 2966 dbSNP
rs933252522 2982 dbSNP
rs1214774998 2985 dbSNP
rs1238010913 2988 dbSNP
rs1052013676 2991 dbSNP
rs11175982 2997 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545212. RNA binding protein: AGO1. Condition:Control ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uucUUUGAUGAUGGAGu 5'
             | ||||||||||| 
Target 5' aacACACUACUACCUCu 3'
 		10 - 26
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293
Disease 8091.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "HITS-CLIP data was present in GSM714642. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uucUUUGAUGAUGGAGu 5'
             | ||||||||||| 
Target 5' aacACACUACUACCUCu 3'
 		10 - 26
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HCT116
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in ERX177629. RNA binding protein: AGO2. Condition:KO_D_AGO_CLIP_4_7 PAR-CLIP data was present in ERX177600. RNA binding protein: AGO2. Condition:p53_V_Ago_CLIP_2_2 PAR-CLIP data was present in ERX177624. RNA binding protein: AGO2. Condition:p53_V_AGO_CLIP_4_2 ...

- Krell J; Stebbing J; Carissimi C; Dabrowska et al., 2016, Genome research.

Article - Krell J; Stebbing J; Carissimi C; Dabrowska et al.
- Genome research, 2016
DNA damage activates TP53-regulated surveillance mechanisms that are crucial in suppressing tumorigenesis. TP53 orchestrates these responses directly by transcriptionally modulating genes, including microRNAs (miRNAs), and by regulating miRNA biogenesis through interacting with the DROSHA complex. However, whether the association between miRNAs and AGO2 is regulated following DNA damage is not yet known. Here, we show that, following DNA damage, TP53 interacts with AGO2 to induce or reduce AGO2's association of a subset of miRNAs, including multiple let-7 family members. Furthermore, we show that specific mutations in TP53 decrease rather than increase the association of let-7 family miRNAs, reducing their activity without preventing TP53 from interacting with AGO2. This is consistent with the oncogenic properties of these mutants. Using AGO2 RIP-seq and PAR-CLIP-seq, we show that the DNA damage-induced increase in binding of let-7 family members to the RISC complex is functional. We unambiguously determine the global miRNA-mRNA interaction networks involved in the DNA damage response, validating them through the identification of miRNA-target chimeras formed by endogenous ligation reactions. We find that the target complementary region of the let-7 seed tends to have highly fixed positions and more variable ones. Additionally, we observe that miRNAs, whose cellular abundance or differential association with AGO2 is regulated by TP53, are involved in an intricate network of regulatory feedback and feedforward circuits. TP53-mediated regulation of AGO2-miRNA interaction represents a new mechanism of miRNA regulation in carcinogenesis.
LinkOut: [PMID: 26701625]
CLIP-seq Support 1 for dataset GSM4903826
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / PID21_NS
Location of target site NM_003483 | 3UTR | AAAACACACUACUACCUCUUAA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161237
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_003483 | 3UTR | UGUUGUACAAUCAAAACACACUACUACCUCUUAA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM714642
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000403681.2 | 3UTR | UACAAUCAAAACACACUACUACCUCUUAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM545212
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / Control
Location of target site ENST00000403681.2 | 3UTR | UACAAUCAAAACACACUACUACCUCUUAAGUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
278 hsa-miR-4500 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT063205 ADIPOR2 adiponectin receptor 2 2 2
MIRT065701 ESPL1 extra spindle pole bodies like 1, separase 2 4
MIRT066489 HMGA2 high mobility group AT-hook 2 2 4
MIRT067415 TMTC3 transmembrane and tetratricopeptide repeat containing 3 2 2
MIRT068169 TXLNA taxilin alpha 2 2
MIRT068540 NHLRC3 NHL repeat containing 3 2 6
MIRT068798 FNDC3A fibronectin type III domain containing 3A 2 2
MIRT073020 ARID3B AT-rich interaction domain 3B 2 6
MIRT073683 IGF1R insulin like growth factor 1 receptor 2 8
MIRT076241 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 6
MIRT077628 IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 2 2
MIRT080409 ONECUT2 one cut homeobox 2 2 2
MIRT083315 ZCCHC3 zinc finger CCHC-type containing 3 2 2
MIRT084989 BACH1 BTB domain and CNC homolog 1 2 2
MIRT094172 PCGF3 polycomb group ring finger 3 2 6
MIRT094475 SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 2 4
MIRT095781 GRPEL2 GrpE like 2, mitochondrial 2 10
MIRT100105 ABT1 activator of basal transcription 1 2 8
MIRT112254 MDM4 MDM4, p53 regulator 2 4
MIRT118595 STK4 serine/threonine kinase 4 2 2
MIRT120932 PDE12 phosphodiesterase 12 2 8
MIRT123336 CALU calumenin 2 2
MIRT123991 POLR3D RNA polymerase III subunit D 2 2
MIRT152317 TNFSF9 TNF superfamily member 9 2 2
MIRT153921 NCOA3 nuclear receptor coactivator 3 2 2
MIRT168608 HMGA1 high mobility group AT-hook 1 2 4
MIRT180614 CRY2 cryptochrome circadian clock 2 2 2
MIRT187726 SUOX sulfite oxidase 2 2
MIRT191415 NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit 2 2
MIRT193113 MAPK6 mitogen-activated protein kinase 6 2 2
MIRT215732 C5ORF51 chromosome 5 open reading frame 51 2 10
MIRT218822 CDKN1A cyclin dependent kinase inhibitor 1A 2 2
MIRT240344 UBXN2B UBX domain protein 2B 2 2
MIRT243480 TRIM71 tripartite motif containing 71 2 2
MIRT244088 EDN1 endothelin 1 2 2
MIRT252341 SALL3 spalt like transcription factor 3 2 2
MIRT255327 CDV3 CDV3 homolog 2 2
MIRT259295 PGRMC1 progesterone receptor membrane component 1 2 2
MIRT259499 TXLNG taxilin gamma 2 2
MIRT260715 CLDN12 claudin 12 2 6
MIRT264701 C11ORF57 chromosome 11 open reading frame 57 2 4
MIRT266228 PEX11B peroxisomal biogenesis factor 11 beta 2 2
MIRT266635 CHTOP chromatin target of PRMT1 2 2
MIRT268847 C1ORF21 chromosome 1 open reading frame 21 2 2
MIRT284540 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT294453 ZNF264 zinc finger protein 264 2 2
MIRT297023 RRM2 ribonucleotide reductase regulatory subunit M2 2 2
MIRT297451 SLC20A1 solute carrier family 20 member 1 2 4
MIRT300049 BZW1 basic leucine zipper and W2 domains 1 2 4
MIRT300907 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT303328 MXD1 MAX dimerization protein 1 2 2
MIRT309858 NAT8L N-acetyltransferase 8 like 2 2
MIRT322434 PPP2R2A protein phosphatase 2 regulatory subunit Balpha 2 2
MIRT324742 ACER2 alkaline ceramidase 2 2 2
MIRT402068 ATP6V1F ATPase H+ transporting V1 subunit F 2 4
MIRT442014 NDUFA4P1 NDUFA4, mitochondrial complex associated pseudogene 1 2 2
MIRT445653 ATP6V1G1 ATPase H+ transporting V1 subunit G1 2 6
MIRT447131 KIF27 kinesin family member 27 2 2
MIRT448262 ZNF774 zinc finger protein 774 2 2
MIRT449002 ANKRD46 ankyrin repeat domain 46 2 2
MIRT449949 FMNL3 formin like 3 2 2
MIRT451150 C19orf53 chromosome 19 open reading frame 53 2 2
MIRT451620 MEIS3P1 Meis homeobox 3 pseudogene 1 2 2
MIRT451689 C1RL complement C1r subcomponent like 2 2
MIRT452087 NUCB2 nucleobindin 2 2 2
MIRT452427 QDPR quinoid dihydropteridine reductase 2 2
MIRT452938 DISC1 disrupted in schizophrenia 1 2 2
MIRT453397 RHD Rh blood group D antigen 2 6
MIRT454159 HIST1H2BK histone cluster 1 H2B family member k 2 2
MIRT454275 FXN frataxin 2 2
MIRT454535 RABL2A RAB, member of RAS oncogene family like 2A 2 2
MIRT454849 ACOT9 acyl-CoA thioesterase 9 2 4
MIRT455671 GLO1 glyoxalase I 2 2
MIRT457243 RABL2B RAB, member of RAS oncogene family like 2B 2 2
MIRT457671 ZNF587 zinc finger protein 587 2 2
MIRT457882 THEM6 thioesterase superfamily member 6 2 4
MIRT458012 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT458275 FUT10 fucosyltransferase 10 2 2
MIRT459732 RRM1 ribonucleotide reductase catalytic subunit M1 2 2
MIRT460447 NOM1 nucleolar protein with MIF4G domain 1 2 4
MIRT460495 FAM105A family with sequence similarity 105 member A 2 6
MIRT460933 NOA1 nitric oxide associated 1 2 4
MIRT461088 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT461164 SLC11A2 solute carrier family 11 member 2 2 4
MIRT461360 COL8A1 collagen type VIII alpha 1 chain 2 2
MIRT462377 YAE1D1 Yae1 domain containing 1 2 2
MIRT462775 ZNF8 zinc finger protein 8 2 2
MIRT463426 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT463656 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT464260 VCL vinculin 2 2
MIRT465121 TSC22D2 TSC22 domain family member 2 2 4
MIRT466190 TMED5 transmembrane p24 trafficking protein 5 2 4
MIRT466728 SYNJ2BP synaptojanin 2 binding protein 2 2
MIRT469098 RNF144B ring finger protein 144B 2 2
MIRT469718 RAB40C RAB40C, member RAS oncogene family 2 2
MIRT470422 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 2
MIRT470684 POLR2D RNA polymerase II subunit D 2 4
MIRT470866 PLXND1 plexin D1 2 2
MIRT471269 PGM2L1 phosphoglucomutase 2 like 1 2 2
MIRT471960 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT472677 NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 2 2
MIRT472735 MTUS1 microtubule associated scaffold protein 1 2 6
MIRT473132 MLLT10 MLLT10, histone lysine methyltransferase DOT1L cofactor 2 2
MIRT473237 SMCR7L mitochondrial elongation factor 1 2 5
MIRT473824 MAP2K7 mitogen-activated protein kinase kinase 7 2 2
MIRT473935 LYN LYN proto-oncogene, Src family tyrosine kinase 2 2
MIRT474020 LRRC20 leucine rich repeat containing 20 2 2
MIRT474504 KLHDC8B kelch domain containing 8B 2 2
MIRT474762 KIAA0930 KIAA0930 2 2
MIRT474912 KCTD21 potassium channel tetramerization domain containing 21 2 2
MIRT475327 IFNLR1 interferon lambda receptor 1 2 2
MIRT475374 ICOSLG inducible T-cell costimulator ligand 2 2
MIRT475729 HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 2 4
MIRT476544 GABPB1 GA binding protein transcription factor beta subunit 1 2 4
MIRT476982 FAM83G family with sequence similarity 83 member G 2 4
MIRT477539 EIF4G2 eukaryotic translation initiation factor 4 gamma 2 2 4
MIRT477676 EFHD2 EF-hand domain family member D2 2 2
MIRT479751 CCND1 cyclin D1 2 2
MIRT481189 ATXN7L3B ataxin 7 like 3B 2 4
MIRT481235 ATXN7L3 ataxin 7 like 3 2 2
MIRT481358 ATG9A autophagy related 9A 2 2
MIRT481383 ATG12 autophagy related 12 2 2
MIRT481647 AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 2 2
MIRT481843 AP1S1 adaptor related protein complex 1 sigma 1 subunit 2 2
MIRT482179 AHR aryl hydrocarbon receptor 2 2
MIRT482215 AHCYL2 adenosylhomocysteinase like 2 2 2
MIRT485301 PLAGL2 PLAG1 like zinc finger 2 2 2
MIRT486654 ZNF28 zinc finger protein 28 2 2
MIRT489409 TUBB2A tubulin beta 2A class IIa 2 2
MIRT491861 ZBTB5 zinc finger and BTB domain containing 5 2 8
MIRT492217 SOCS1 suppressor of cytokine signaling 1 2 2
MIRT492632 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2 2
MIRT493320 LIMD2 LIM domain containing 2 2 2
MIRT493897 FAM43A family with sequence similarity 43 member A 2 4
MIRT494259 CEP120 centrosomal protein 120 2 2
MIRT494681 ARID3A AT-rich interaction domain 3A 2 2
MIRT495963 TBC1D19 TBC1 domain family member 19 2 2
MIRT496117 SNX17 sorting nexin 17 2 2
MIRT497870 SLC12A7 solute carrier family 12 member 7 2 2
MIRT498115 PLEKHO1 pleckstrin homology domain containing O1 2 4
MIRT499400 PLCG2 phospholipase C gamma 2 2 4
MIRT499489 GGA3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 2 2
MIRT499648 SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 2 2
MIRT499937 MFSD8 major facilitator superfamily domain containing 8 2 2
MIRT499993 HIST1H2BD histone cluster 1 H2B family member d 2 4
MIRT500821 THBS1 thrombospondin 1 2 3
MIRT500900 STRN striatin 2 4
MIRT501111 SLC5A6 solute carrier family 5 member 6 2 4
MIRT501179 SLC10A7 solute carrier family 10 member 7 2 6
MIRT501206 SUMO1 small ubiquitin-like modifier 1 2 2
MIRT501249 SEMA4C semaphorin 4C 2 6
MIRT501334 RNFT1 ring finger protein, transmembrane 1 2 2
MIRT501357 RNF44 ring finger protein 44 2 4
MIRT501394 RBFOX2 RNA binding protein, fox-1 homolog 2 2 10
MIRT501437 RAB11FIP4 RAB11 family interacting protein 4 2 2
MIRT501749 NSD1 nuclear receptor binding SET domain protein 1 2 2
MIRT501939 MBD2 methyl-CpG binding domain protein 2 2 8
MIRT502104 KPNA5 karyopherin subunit alpha 5 2 8
MIRT502123 KMT2D lysine methyltransferase 2D 2 4
MIRT502787 CEP135 centrosomal protein 135 2 2
MIRT502839 CELF1 CUGBP Elav-like family member 1 2 2
MIRT504783 C12orf4 chromosome 12 open reading frame 4 2 2
MIRT505020 ZNF644 zinc finger protein 644 2 2
MIRT505577 SMC1A structural maintenance of chromosomes 1A 2 6
MIRT506359 NUP155 nucleoporin 155 2 6
MIRT506936 IGDCC4 immunoglobulin superfamily DCC subclass member 4 2 6
MIRT507248 FIGN fidgetin, microtubule severing factor 2 8
MIRT507691 COIL coilin 2 6
MIRT508397 C1orf210 chromosome 1 open reading frame 210 2 6
MIRT508660 DIABLO diablo IAP-binding mitochondrial protein 2 4
MIRT508927 AK4 adenylate kinase 4 2 4
MIRT510387 ZNF566 zinc finger protein 566 2 6
MIRT510521 YOD1 YOD1 deubiquitinase 2 6
MIRT511381 IKZF3 IKAROS family zinc finger 3 2 4
MIRT512740 CD59 CD59 molecule (CD59 blood group) 2 4
MIRT515949 C9orf156 tRNA methyltransferase O 2 2
MIRT516078 ZBTB8OS zinc finger and BTB domain containing 8 opposite strand 2 4
MIRT521392 RDX radixin 2 4
MIRT522344 NCKIPSD NCK interacting protein with SH3 domain 2 4
MIRT523623 FZD9 frizzled class receptor 9 2 4
MIRT523728 FBXW2 F-box and WD repeat domain containing 2 2 4
MIRT523981 DVL3 dishevelled segment polarity protein 3 2 2
MIRT524108 DNA2 DNA replication helicase/nuclease 2 2 2
MIRT525722 SOD2 superoxide dismutase 2 2 2
MIRT527758 RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator 2 2
MIRT529722 OPRL1 opioid related nociceptin receptor 1 2 2
MIRT533183 WASL Wiskott-Aldrich syndrome like 2 6
MIRT536373 LEFTY1 left-right determination factor 1 2 2
MIRT543781 RBM12B RNA binding motif protein 12B 2 4
MIRT543863 SLC16A9 solute carrier family 16 member 9 2 2
MIRT545383 PM20D2 peptidase M20 domain containing 2 2 2
MIRT545895 ZNF200 zinc finger protein 200 2 4
MIRT546328 TGFBR3 transforming growth factor beta receptor 3 2 2
MIRT547374 MSI2 musashi RNA binding protein 2 2 2
MIRT547577 LRIG3 leucine rich repeats and immunoglobulin like domains 3 2 4
MIRT547834 IGF2BP3 insulin like growth factor 2 mRNA binding protein 3 2 4
MIRT548260 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT548342 EPHA4 EPH receptor A4 2 2
MIRT548539 DUSP1 dual specificity phosphatase 1 2 2
MIRT548554 DNAL1 dynein axonemal light chain 1 2 2
MIRT548787 COLEC12 collectin subfamily member 12 2 2
MIRT548976 CCNT2 cyclin T2 2 2
MIRT549026 CBX5 chromobox 5 2 2
MIRT549213 BEND4 BEN domain containing 4 2 4
MIRT549759 ZNF611 zinc finger protein 611 2 6
MIRT549794 KIAA0391 KIAA0391 2 2
MIRT549843 ECHDC1 ethylmalonyl-CoA decarboxylase 1 2 2
MIRT550723 PMPCA peptidase, mitochondrial processing alpha subunit 2 4
MIRT550893 ACTA1 actin, alpha 1, skeletal muscle 2 2
MIRT551277 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 6
MIRT551313 GSG2 histone H3 associated protein kinase 2 6
MIRT551928 AKAP8 A-kinase anchoring protein 8 2 4
MIRT551998 RAD18 RAD18, E3 ubiquitin protein ligase 2 2
MIRT552405 ZNF460 zinc finger protein 460 2 4
MIRT553016 USP38 ubiquitin specific peptidase 38 2 2
MIRT555544 PLEKHA3 pleckstrin homology domain containing A3 2 2
MIRT555716 PDZD8 PDZ domain containing 8 2 2
MIRT557377 HAND1 heart and neural crest derivatives expressed 1 2 2
MIRT557957 FAM222B family with sequence similarity 222 member B 2 2
MIRT559086 C19orf47 chromosome 19 open reading frame 47 2 4
MIRT559493 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2 2
MIRT561777 PEG10 paternally expressed 10 2 2
MIRT564396 EMILIN2 elastin microfibril interfacer 2 2 4
MIRT565445 SURF4 surfeit 4 2 2
MIRT566514 PARP16 poly(ADP-ribose) polymerase family member 16 2 2
MIRT567437 GNG5 G protein subunit gamma 5 2 2
MIRT567712 E2F6 E2F transcription factor 6 2 2
MIRT568652 ABHD17C abhydrolase domain containing 17C 2 2
MIRT569493 THYN1 thymocyte nuclear protein 1 2 2
MIRT573816 TGOLN2 trans-golgi network protein 2 2 2
MIRT574358 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT574754 GOLGA4 golgin A4 2 2
MIRT574791 FAM104A family with sequence similarity 104 member A 2 2
MIRT576081 Poteg POTE ankyrin domain family, member G 2 2
MIRT576813 Thbs1 thrombospondin 1 2 3
MIRT616365 RWDD1 RWD domain containing 1 2 2
MIRT617846 FMO4 flavin containing monooxygenase 4 2 2
MIRT642389 ZNF556 zinc finger protein 556 2 2
MIRT680514 PRIM2 DNA primase subunit 2 2 2
MIRT680542 ZNF584 zinc finger protein 584 2 2
MIRT680795 ZNF578 zinc finger protein 578 2 2
MIRT680833 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT681136 INTS7 integrator complex subunit 7 2 2
MIRT681266 RFC2 replication factor C subunit 2 2 2
MIRT681318 ZFAND4 zinc finger AN1-type containing 4 2 4
MIRT681354 BRI3BP BRI3 binding protein 2 2
MIRT681501 STAT2 signal transducer and activator of transcription 2 2 2
MIRT681531 ZNF738 zinc finger protein 738 2 2
MIRT681653 DTX3L deltex E3 ubiquitin ligase 3L 2 2
MIRT681733 RAB19 RAB19, member RAS oncogene family 2 4
MIRT681756 CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 2 2
MIRT681792 EIF4A3 eukaryotic translation initiation factor 4A3 2 2
MIRT681864 DNAH9 dynein axonemal heavy chain 9 2 2
MIRT681936 SLC19A3 solute carrier family 19 member 3 2 2
MIRT682097 ITGA3 integrin subunit alpha 3 2 4
MIRT682177 SLC38A7 solute carrier family 38 member 7 2 2
MIRT682233 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT682379 PHACTR4 phosphatase and actin regulator 4 2 2
MIRT682439 MTX3 metaxin 3 2 2
MIRT682599 CPA4 carboxypeptidase A4 2 2
MIRT682635 COX6B1 cytochrome c oxidase subunit 6B1 2 2
MIRT689323 FPR1 formyl peptide receptor 1 2 2
MIRT689725 ATXN2 ataxin 2 2 2
MIRT691031 ZNF799 zinc finger protein 799 2 2
MIRT691930 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 2
MIRT694879 ZNF417 zinc finger protein 417 2 2
MIRT695250 ZNF443 zinc finger protein 443 2 2
MIRT695408 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2 2
MIRT700593 PRSS22 protease, serine 22 2 2
MIRT701434 NHLRC2 NHL repeat containing 2 2 2
MIRT702479 KIAA1328 KIAA1328 2 2
MIRT702716 IPO9 importin 9 2 2
MIRT704036 EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 2 2
MIRT704415 CTPS1 CTP synthase 1 2 2
MIRT705745 AMD1 adenosylmethionine decarboxylase 1 2 2
MIRT712369 NAP1L1 nucleosome assembly protein 1 like 1 2 2
MIRT713515 PAFAH2 platelet activating factor acetylhydrolase 2 2 2
MIRT735773 STAT3 signal transducer and activator of transcription 3 6 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4500 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)

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