miRTarBase - #MIRT068751


—
pre-miRNA Information
pre-miRNA hsa-mir-519c   
Genomic Coordinates chr19: 53686469 - 53686555
Description Homo sapiens miR-519c stem-loop
Comment The 5' arm of this precursor expresses a product related to miR-526 (previously named miR-526c here). Landgraf et al. confirm mature miRNA expression from both arms of the precursor .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-519c-3p
Sequence 54| AAAGUGCAUCUUUUUAGAGGAU |75
Evidence Experimental
Experiments Array-cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 2 19 + 53686523 29233923 MiREDiBase
A-to-I 3 19 + 53686524 29233923 MiREDiBase
A-to-I 8 19 + 53686529 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1164669230 4 dbSNP
rs764425172 8 dbSNP
rs1377433094 10 dbSNP
rs751997873 19 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol RB1   
Synonyms OSRC, PPP1R130, RB, p105-Rb, pRb, pp110
Description RB transcriptional corepressor 1
Transcript NM_000321   
Expression
Putative miRNA Targets on RB1
3'UTR of RB1
(miRNA target sites are highlighted)		 
>RB1|NM_000321|3'UTR
   1 GGATCTCAGGACCTTGGTGGACACTGTGTACACCTCTGGATTCATTGTCTCTCACAGATGTGACTGTATAACTTTCCCAG
  81 GTTCTGTTTATGGCCACATTTAATATCTTCAGCTCTTTTTGTGGATATAAAATGTGCAGATGCAATTGTTTGGGTGATTC
 161 CTAAGCCACTTGAAATGTTAGTCATTGTTATTTATACAAGATTGAAAATCTTGTGTAAATCCTGCCATTTAAAAAGTTGT
 241 AGCAGATTGTTTCCTCTTCCAAAGTAAAATTGCTGTGCTTTATGGATAGTAAGAATGGCCCTAGAGTGGGAGTCCTGATA
 321 ACCCAGGCCTGTCTGACTACTTTGCCTTCTTTTGTAGCATATAGGTGATGTTTGCTCTTGTTTTTATTAATTTATATGTA
 401 TATTTTTTTAATTTAACATGAACACCCTTAGAAAATGTGTCCTATCTATCTTCCAAATGCAATTTGATTGACTGCCCATT
 481 CACCAAAATTATCCTGAACTCTTCTGCAAAAATGGATATTATTAGAAATTAGAAAAAAATTACTAATTTTACACATTAGA
 561 TTTTATTTTACTATTGGAATCTGATATACTGTGTGCTTGTTTTATAAAATTTTGCTTTTAATTAAATAAAAGCTGGAAGC
 641 AAAGTATAACCATATGATACTATCATACTACTGAAACAGATTTCATACCTCAGAATGTAAAAGAACTTACTGATTATTTT
 721 CTTCATCCAACTTATGTTTTTAAATGAGGATTATTGATAGTACTCTTGGTTTTTATACCATTCAGATCACTGAATTTATA
 801 AAGTACCCATCTAGTACTTGAAAAAGTAAAGTGTTCTGCCAGATCTTAGGTATAGAGGACCCTAACACAGTATATCCCAA
 881 GTGCACTTTCTAATGTTTCTGGGTCCTGAAGAATTAAGATACAAATTAATTTTACTCCATAAACAGACTGTTAATTATAG
 961 GAGCCTTAATTTTTTTTTCATAGAGATTTGTCTAATTGCATCTCAAAATTATTCTGCCCTCCTTAATTTGGGAAGGTTTG
1041 TGTTTTCTCTGGAATGGTACATGTCTTCCATGTATCTTTTGAACTGGCAATTGTCTATTTATCTTTTATTTTTTTAAGTC
1121 AGTATGGTCTAACACTGGCATGTTCAAAGCCACATTATTTCTAGTCCAAAATTACAAGTAATCAAGGGTCATTATGGGTT
1201 AGGCATTAATGTTTCTATCTGATTTTGTGCAAAAGCTTCAAATTAAAACAGCTGCATTAGAAAAAGAGGCGCTTCTCCCC
1281 TCCCCTACACCTAAAGGTGTATTTAAACTATCTTGTGTGATTAACTTATTTAGAGATGCTGTAACTTAAAATAGGGGATA
1361 TTTAAGGTAGCTTCAGCTAGCTTTTAGGAAAATCACTTTGTCTAACTCAGAATTATTTTTAAAAAGAAATCTGGTCTTGT
1441 TAGAAAACAAAATTTTATTTTGTGCTCATTTAAGTTTCAAACTTACTATTTTGACAGTTATTTTGATAACAATGACACTA
1521 GAAAACTTGACTCCATTTCATCATTGTTTCTGCATGAATATCATACAAATCAGTTAGTTTTTAGGTCAAGGGCTTACTAT
1601 TTCTGGGTCTTTTGCTACTAAGTTCACATTAGAATTAGTGCCAGAATTTTAGGAACTTCAGAGATCGTGTATTGAGATTT
1681 CTTAAATAATGCTTCAGATATTATTGCTTTATTGCTTTTTTGTATTGGTTAAAACTGTACATTTAAAATTGCTATGTTAC
1761 TATTTTCTACAATTAATAGTTTGTCTATTTTAAAATAAATTAGTTGTTAAGAGTCTTAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uaggagauuuUUCUACGUGAAa 5'
                    ||| ||||||| 
Target 5' agtatatcccAAG-TGCACTTt 3'
 869 - 889 147.00 -11.20
2 
miRNA  3' uaGGAGAU-U---UUUCUACGUGAAa 5'
            || ||| |   ||||:||:|:|| 
Target 5' ctCCCCTACACCTAAAGGTGTATTTa 3'
 1280 - 1305 136.00 -13.10
3 
miRNA  3' uaggAGAUUUU-----UCUACGUGAAa 5'
              | |||||     ||||||| || 
Target 5' tggaTATAAAATGTGCAGATGCAATTg 3'
 122 - 148 134.00 -7.26
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
881110 69 ClinVar
312298 163 ClinVar
312299 173 ClinVar
312300 185 ClinVar
881578 250 ClinVar
881579 393 ClinVar
312301 399 ClinVar
312302 414 ClinVar
312303 436 ClinVar
312304 442 ClinVar
312305 464 ClinVar
312306 513 ClinVar
881580 574 ClinVar
312307 605 ClinVar
312308 674 ClinVar
312309 704 ClinVar
312310 789 ClinVar
312311 965 ClinVar
312312 999 ClinVar
312313 1023 ClinVar
882729 1045 ClinVar
312314 1269 ClinVar
882730 1409 ClinVar
312315 1460 ClinVar
312316 1527 ClinVar
312317 1541 ClinVar
312318 1545 ClinVar
312319 1636 ClinVar
312320 1688 ClinVar
883517 1708 ClinVar
883518 1749 ClinVar
883519 1772 ClinVar
COSN25904796 9 COSMIC
COSN30466223 20 COSMIC
COSN30133234 58 COSMIC
COSN9086040 80 COSMIC
COSN31608457 101 COSMIC
COSN30497947 136 COSMIC
COSN8587643 153 COSMIC
COSN31599476 206 COSMIC
COSN26562103 399 COSMIC
COSN26664145 401 COSMIC
COSN30540943 423 COSMIC
COSN31519721 541 COSMIC
COSN21693009 722 COSMIC
COSN31515729 733 COSMIC
COSN31488206 843 COSMIC
COSN17181893 914 COSMIC
COSN19664813 979 COSMIC
COSN15668271 1604 COSMIC
COSN31520569 1610 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1377688261 3 dbSNP
rs776159301 4 dbSNP
rs1244602086 8 dbSNP
rs1444863901 11 dbSNP
rs1182513365 13 dbSNP
rs780696352 15 dbSNP
rs754324625 18 dbSNP
rs755363743 23 dbSNP
rs1318599730 24 dbSNP
rs1344482362 25 dbSNP
rs778758342 26 dbSNP
rs544256732 27 dbSNP
rs771646201 28 dbSNP
rs777078797 29 dbSNP
rs372459968 30 dbSNP
rs377188800 32 dbSNP
rs1415887695 33 dbSNP
rs370626097 33 dbSNP
rs769550932 34 dbSNP
rs376192929 36 dbSNP
rs368462035 37 dbSNP
rs1040215371 40 dbSNP
rs769180580 40 dbSNP
rs1216386843 42 dbSNP
rs371663196 44 dbSNP
rs1448162804 45 dbSNP
rs533165692 50 dbSNP
rs76558254 52 dbSNP
rs1327245272 56 dbSNP
rs929201070 57 dbSNP
rs1409795356 65 dbSNP
rs1047890795 67 dbSNP
rs547352312 69 dbSNP
rs1471942942 78 dbSNP
rs1384617226 82 dbSNP
rs1211475380 83 dbSNP
rs1251058708 84 dbSNP
rs1239982538 91 dbSNP
rs1006267460 98 dbSNP
rs1202390798 100 dbSNP
rs1290343121 104 dbSNP
rs1211194641 107 dbSNP
rs527847204 127 dbSNP
rs182470177 128 dbSNP
rs768771487 133 dbSNP
rs1026267962 143 dbSNP
rs1379724508 147 dbSNP
rs1278256224 154 dbSNP
rs1049723 159 dbSNP
rs886050273 163 dbSNP
rs1350777508 168 dbSNP
rs886084957 170 dbSNP
rs763603568 171 dbSNP
rs143536240 173 dbSNP
rs1159293937 178 dbSNP
rs4151630 185 dbSNP
rs1378568995 188 dbSNP
rs549500314 189 dbSNP
rs1291302040 190 dbSNP
rs1175349461 192 dbSNP
rs1434863917 200 dbSNP
rs974466753 203 dbSNP
rs571221099 212 dbSNP
rs1022258064 214 dbSNP
rs751747456 222 dbSNP
rs148064671 243 dbSNP
rs1290634381 248 dbSNP
rs985843170 264 dbSNP
rs1030422432 268 dbSNP
rs1281590616 279 dbSNP
rs1355168581 286 dbSNP
rs1281546857 295 dbSNP
rs954940558 307 dbSNP
rs911335091 315 dbSNP
rs187845274 317 dbSNP
rs566016487 323 dbSNP
rs1345307686 326 dbSNP
rs1298974961 332 dbSNP
rs1421767183 334 dbSNP
rs1343438961 337 dbSNP
rs1158560250 343 dbSNP
rs1301590789 347 dbSNP
rs1425848995 353 dbSNP
rs936933563 371 dbSNP
rs1350124520 375 dbSNP
rs1193844529 378 dbSNP
rs975948170 378 dbSNP
rs916588731 379 dbSNP
rs1214510557 381 dbSNP
rs1239844898 381 dbSNP
rs923098277 384 dbSNP
rs1313278614 393 dbSNP
rs929093283 394 dbSNP
rs1222258505 398 dbSNP
rs886050274 399 dbSNP
rs762279268 402 dbSNP
rs1279250384 403 dbSNP
rs948087111 403 dbSNP
rs1435948022 407 dbSNP
rs1206563438 410 dbSNP
rs886050275 414 dbSNP
rs1211646587 417 dbSNP
rs1233203850 424 dbSNP
rs886050276 436 dbSNP
rs1360988840 438 dbSNP
rs746086958 442 dbSNP
rs886050277 442 dbSNP
rs1047648489 443 dbSNP
rs887668091 447 dbSNP
rs545399716 449 dbSNP
rs907025087 451 dbSNP
rs1429919393 463 dbSNP
rs4151631 464 dbSNP
rs1185599426 465 dbSNP
rs1483269368 469 dbSNP
rs1048091793 480 dbSNP
rs1202270604 484 dbSNP
rs1290701934 499 dbSNP
rs886050278 513 dbSNP
rs905654319 516 dbSNP
rs1454452086 517 dbSNP
rs886327988 523 dbSNP
rs554797831 524 dbSNP
rs1006111060 533 dbSNP
rs1305963158 534 dbSNP
rs1295061746 538 dbSNP
rs1015842066 541 dbSNP
rs754495142 542 dbSNP
rs1334800605 545 dbSNP
rs560967910 571 dbSNP
rs1450335586 574 dbSNP
rs150194261 575 dbSNP
rs995874400 587 dbSNP
rs1030060998 588 dbSNP
rs1371162411 592 dbSNP
rs1002573715 596 dbSNP
rs886050279 605 dbSNP
rs1386545996 616 dbSNP
rs1181291979 623 dbSNP
rs1056767538 628 dbSNP
rs1440699032 632 dbSNP
rs891969857 634 dbSNP
rs1324124483 635 dbSNP
rs1010789279 648 dbSNP
rs1373379546 658 dbSNP
rs1239370799 670 dbSNP
rs999671455 672 dbSNP
rs886050280 674 dbSNP
rs1031606915 688 dbSNP
rs1021899447 693 dbSNP
rs969360031 695 dbSNP
rs1006922636 697 dbSNP
rs139023385 704 dbSNP
rs1323789082 711 dbSNP
rs1313001552 719 dbSNP
rs989741878 727 dbSNP
rs916579005 732 dbSNP
rs1309842962 733 dbSNP
rs1216225586 735 dbSNP
rs1297452118 737 dbSNP
rs969414641 741 dbSNP
rs1273687798 750 dbSNP
rs1320885421 760 dbSNP
rs1211521554 761 dbSNP
rs1161109375 774 dbSNP
rs1254673091 779 dbSNP
rs1443429000 779 dbSNP
rs982171614 781 dbSNP
rs1184515071 782 dbSNP
rs1417865562 784 dbSNP
rs965494313 787 dbSNP
rs886050281 789 dbSNP
rs143145266 798 dbSNP
rs767973301 805 dbSNP
rs755122737 806 dbSNP
rs1187575932 807 dbSNP
rs950593415 812 dbSNP
rs1354421847 814 dbSNP
rs750952060 829 dbSNP
rs4151632 856 dbSNP
rs941933291 857 dbSNP
rs1044079175 861 dbSNP
rs1170138155 863 dbSNP
rs926963340 874 dbSNP
rs1420928439 884 dbSNP
rs1461378962 887 dbSNP
rs1387185503 895 dbSNP
rs1163150948 903 dbSNP
rs1300855223 908 dbSNP
rs545016882 915 dbSNP
rs560398159 925 dbSNP
rs938314055 931 dbSNP
rs752896094 932 dbSNP
rs1452251735 946 dbSNP
rs1363763858 950 dbSNP
rs941918069 959 dbSNP
rs1397167293 961 dbSNP
rs1481602977 962 dbSNP
rs4151633 965 dbSNP
rs529114215 970 dbSNP
rs900158900 970 dbSNP
rs1324739431 971 dbSNP
rs1433064737 976 dbSNP
rs1203514496 979 dbSNP
rs1348427539 982 dbSNP
rs1260023791 988 dbSNP
rs1224080573 991 dbSNP
rs1270851590 998 dbSNP
rs886050282 999 dbSNP
rs1334000237 1017 dbSNP
rs778624725 1020 dbSNP
rs886050283 1023 dbSNP
rs1281154031 1032 dbSNP
rs192758219 1037 dbSNP
rs1043605723 1045 dbSNP
rs904809687 1055 dbSNP
rs1380072355 1059 dbSNP
rs890190003 1071 dbSNP
rs1007552591 1073 dbSNP
rs1471251780 1091 dbSNP
rs745647859 1103 dbSNP
rs200353673 1109 dbSNP
rs561568186 1125 dbSNP
rs965379179 1134 dbSNP
rs1478254242 1137 dbSNP
rs1204167655 1148 dbSNP
rs531819305 1151 dbSNP
rs958484440 1155 dbSNP
rs549853297 1189 dbSNP
rs1446461456 1191 dbSNP
rs1193184590 1196 dbSNP
rs746886992 1215 dbSNP
rs1011162918 1219 dbSNP
rs1204154035 1220 dbSNP
rs1025757645 1230 dbSNP
rs951533036 1231 dbSNP
rs983337161 1240 dbSNP
rs1236395343 1242 dbSNP
rs1222710769 1249 dbSNP
rs1339627214 1251 dbSNP
rs1475137530 1254 dbSNP
rs1023913699 1256 dbSNP
rs1420431711 1257 dbSNP
rs143174150 1261 dbSNP
rs909035277 1262 dbSNP
rs1325297702 1267 dbSNP
rs571383547 1269 dbSNP
rs1336887466 1271 dbSNP
rs969362383 1272 dbSNP
rs1404586773 1274 dbSNP
rs979994619 1278 dbSNP
rs182363120 1280 dbSNP
rs1336462447 1281 dbSNP
rs1466423488 1286 dbSNP
rs982078097 1300 dbSNP
rs1166303044 1314 dbSNP
rs371878105 1326 dbSNP
rs1475216133 1334 dbSNP
rs1369112861 1339 dbSNP
rs1185569278 1341 dbSNP
rs1446335181 1354 dbSNP
rs1241248271 1378 dbSNP
rs1202979673 1382 dbSNP
rs1158197912 1385 dbSNP
rs547447407 1391 dbSNP
rs1274878430 1394 dbSNP
rs927971862 1401 dbSNP
rs1338426206 1406 dbSNP
rs1315102846 1409 dbSNP
rs1247601117 1416 dbSNP
rs927181977 1424 dbSNP
rs559170385 1442 dbSNP
rs1314916766 1444 dbSNP
rs1443567762 1448 dbSNP
rs753514209 1453 dbSNP
rs886050284 1460 dbSNP
rs1056709939 1461 dbSNP
rs536592189 1462 dbSNP
rs1804280 1467 dbSNP
rs1327335663 1472 dbSNP
rs913011967 1475 dbSNP
rs1409601738 1483 dbSNP
rs1366468005 1488 dbSNP
rs1165521019 1502 dbSNP
rs1422763770 1507 dbSNP
rs945780336 1513 dbSNP
rs951456420 1514 dbSNP
rs1402677990 1519 dbSNP
rs1043271147 1520 dbSNP
rs770204264 1520 dbSNP
rs904693037 1523 dbSNP
rs1234393153 1527 dbSNP
rs540108904 1527 dbSNP
rs1319010638 1528 dbSNP
rs1291992561 1535 dbSNP
rs1224291933 1536 dbSNP
rs1356560699 1537 dbSNP
rs942812871 1540 dbSNP
rs768155412 1541 dbSNP
rs1412828111 1543 dbSNP
rs886050285 1545 dbSNP
rs548857788 1546 dbSNP
rs4151634 1548 dbSNP
rs998215955 1555 dbSNP
rs1355844268 1557 dbSNP
rs1037569517 1564 dbSNP
rs1346561282 1588 dbSNP
rs1305141311 1590 dbSNP
rs1238154099 1591 dbSNP
rs1277555336 1600 dbSNP
rs921823911 1605 dbSNP
rs1205375502 1607 dbSNP
rs931918561 1620 dbSNP
rs886050286 1636 dbSNP
rs1278939207 1637 dbSNP
rs554578148 1660 dbSNP
rs1025643013 1665 dbSNP
rs1269339459 1667 dbSNP
rs887237662 1668 dbSNP
rs1489753421 1670 dbSNP
rs1006051707 1678 dbSNP
rs1804276 1679 dbSNP
rs1016983640 1686 dbSNP
rs569786158 1687 dbSNP
rs4151635 1688 dbSNP
rs755984043 1708 dbSNP
rs371337708 1716 dbSNP
rs979878993 1716 dbSNP
rs1034255519 1723 dbSNP
rs1223741526 1724 dbSNP
rs890128261 1725 dbSNP
rs556205552 1749 dbSNP
rs376808474 1756 dbSNP
rs1221912166 1762 dbSNP
rs1345163275 1767 dbSNP
rs577749913 1772 dbSNP
rs538626210 1773 dbSNP
rs1159408507 1778 dbSNP
rs1374905887 1779 dbSNP
rs1316055563 1780 dbSNP
rs1429716428 1782 dbSNP
rs992488554 1782 dbSNP
rs1178403926 1789 dbSNP
rs1479234078 1803 dbSNP
rs1424089076 1820 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 5925.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uaggagauuuUUCUACGUGAAa 5'
                    ||| ||||||| 
Target 5' aguauaucccAAG-UGCACUUu 3'
 		11 - 31
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000267163.4 | 3UTR | ACCCUAACACAGUAUAUCCCAAGUGCACUUUCUAAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28260 Renal cortex and medulla 0.74 1.9e-3 0.676 5.6e-3 13 Click to see details
GSE38226 Liver fibrosis -0.35 6.0e-2 0.023 4.6e-1 21 Click to see details
GSE14794 Lymphoblastoid cells -0.163 6.2e-2 -0.221 1.8e-2 90 Click to see details
GSE19350 CNS germ cell tumors -0.402 9.8e-2 -0.309 1.6e-1 12 Click to see details
GSE28544 Breast cancer -0.17 2.1e-1 -0.186 1.9e-1 24 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.318 2.2e-1 0.333 2.1e-1 8 Click to see details
GSE26953 Aortic valvular endothelial cells -0.135 2.6e-1 -0.087 3.4e-1 24 Click to see details
GSE27834 Pluripotent stem cells 0.156 2.8e-1 -0.003 5.0e-1 16 Click to see details
GSE17498 Multiple myeloma -0.086 3.0e-1 -0.153 1.7e-1 40 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.099 3.2e-1 0.246 1.2e-1 25 Click to see details
GSE21849 B cell lymphoma -0.085 3.3e-1 -0.060 3.8e-1 29 Click to see details
GSE42095 Differentiated embryonic stem cells -0.088 3.4e-1 -0.269 1.1e-1 23 Click to see details
GSE17306 Multiple myeloma 0.042 3.9e-1 0.475 2.8e-4 49 Click to see details
GSE32688 Pancreatic cancer 0.048 4.0e-1 0.053 3.9e-1 32 Click to see details
GSE21687 Ependynoma primary tumors -0.024 4.3e-1 -0.119 1.7e-1 64 Click to see details
GSE35602 Colorectal cancer stromal tissue 0.033 4.4e-1 0.468 9.2e-3 25 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.021 4.6e-1 -0.471 1.8e-2 20 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
BRCA 0.942 0.01 0.700 0.09 5 Click to see details
LIHC -0.584 0.21 -0.400 0.3 4 Click to see details
HNSC -0.317 0.4 -0.500 0.33 3 Click to see details
HNSC -0.317 0.4 -0.500 0.33 3 Click to see details
HNSC -0.317 0.4 -0.500 0.33 3 Click to see details
HNSC -0.317 0.4 -0.500 0.33 3 Click to see details
325 hsa-miR-519c-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT000496 HIF1A hypoxia inducible factor 1 alpha subunit 4 1
MIRT000998 ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) 4 3
MIRT003732 ELAVL1 ELAV like RNA binding protein 1 3 1
MIRT006639 TIMP2 TIMP metallopeptidase inhibitor 2 3 1
MIRT006640 PTEN phosphatase and tensin homolog 3 1
MIRT006641 CDKN1A cyclin dependent kinase inhibitor 1A 3 1
MIRT055028 TPRG1L tumor protein p63 regulated 1 like 2 2
MIRT055393 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 6
MIRT056828 REEP3 receptor accessory protein 3 2 2
MIRT060504 PPP6R3 protein phosphatase 6 regulatory subunit 3 2 2
MIRT061796 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 10
MIRT063354 ETNK1 ethanolamine kinase 1 2 2
MIRT064424 ARID4B AT-rich interaction domain 4B 2 2
MIRT064719 CCND2 cyclin D2 2 2
MIRT064805 ZBTB18 zinc finger and BTB domain containing 18 2 4
MIRT065609 DAZAP2 DAZ associated protein 2 2 10
MIRT065622 CLIC4 chloride intracellular channel 4 2 4
MIRT065872 GDF11 growth differentiation factor 11 2 2
MIRT065892 RAB5B RAB5B, member RAS oncogene family 2 8
MIRT068751 RB1 RB transcriptional corepressor 1 2 2
MIRT070050 FANCM Fanconi anemia complementation group M 2 2
MIRT071004 SMOC1 SPARC related modular calcium binding 1 2 2
MIRT071334 CMPK1 cytidine/uridine monophosphate kinase 1 2 6
MIRT071912 ZFYVE9 zinc finger FYVE-type containing 9 2 2
MIRT072732 GLCE glucuronic acid epimerase 2 2
MIRT076028 COX10 COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor 2 6
MIRT076046 PITPNA phosphatidylinositol transfer protein alpha 2 2
MIRT079353 CCDC137 coiled-coil domain containing 137 2 2
MIRT080227 SMAD4 SMAD family member 4 2 6
MIRT081122 LDLR low density lipoprotein receptor 2 8
MIRT081205 MIDN midnolin 2 10
MIRT085098 IFNAR2 interferon alpha and beta receptor subunit 2 2 6
MIRT085149 SLC5A3 solute carrier family 5 member 3 2 4
MIRT086436 NABP1 nucleic acid binding protein 1 2 6
MIRT088037 UBXN2A UBX domain protein 2A 2 2
MIRT088132 SEPT2 septin 2 2 4
MIRT088343 MAPRE3 microtubule associated protein RP/EB family member 3 2 8
MIRT090645 U2SURP U2 snRNP associated SURP domain containing 2 6
MIRT090805 MBNL1 muscleblind like splicing regulator 1 2 4
MIRT091692 TGFBR2 transforming growth factor beta receptor 2 2 4
MIRT092689 C3ORF38 chromosome 3 open reading frame 38 2 8
MIRT093954 SLAIN2 SLAIN motif family member 2 2 2
MIRT095727 ANKH ANKH inorganic pyrophosphate transport regulator 2 8
MIRT097158 FCHO2 FCH domain only 2 2 2
MIRT099319 QKI QKI, KH domain containing RNA binding 2 4
MIRT099835 SOX4 SRY-box 4 2 10
MIRT100773 ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 2 2
MIRT100955 CENPQ centromere protein Q 2 4
MIRT102229 HBP1 HMG-box transcription factor 1 2 2
MIRT102299 DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 2 10
MIRT102621 UBN2 ubinuclein 2 2 8
MIRT103780 PURB purine rich element binding protein B 2 2
MIRT104168 PHTF2 putative homeodomain transcription factor 2 2 6
MIRT107279 FAM73B mitoguardin 2 2 2
MIRT107945 TMEM2 transmembrane protein 2 2 2
MIRT108265 HABP4 hyaluronan binding protein 4 2 2
MIRT124812 BICD2 BICD cargo adaptor 2 2 2
MIRT138707 MPP5 membrane palmitoylated protein 5 2 2
MIRT139880 BTF3L4 basic transcription factor 3 like 4 2 6
MIRT144312 NFAT5 nuclear factor of activated T-cells 5 2 8
MIRT145605 LASP1 LIM and SH3 protein 1 2 2
MIRT153350 MAVS mitochondrial antiviral signaling protein 2 4
MIRT153986 PRNP prion protein 2 2
MIRT159129 NRBP1 nuclear receptor binding protein 1 2 2
MIRT164533 MSMO1 methylsterol monooxygenase 1 2 2
MIRT165912 CREBRF CREB3 regulatory factor 2 2
MIRT170858 TAX1BP1 Tax1 binding protein 1 2 4
MIRT172157 FZD6 frizzled class receptor 6 2 8
MIRT173701 PRPF4 pre-mRNA processing factor 4 2 2
MIRT175003 ZBTB5 zinc finger and BTB domain containing 5 2 4
MIRT175400 ACSL4 acyl-CoA synthetase long chain family member 4 2 2
MIRT178069 SAMD8 sterile alpha motif domain containing 8 2 2
MIRT178675 FAM102B family with sequence similarity 102 member B 2 2
MIRT180847 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 4
MIRT194911 RBBP6 RB binding protein 6, ubiquitin ligase 2 8
MIRT195755 ATMIN ATM interactor 2 6
MIRT196623 TAOK1 TAO kinase 1 2 6
MIRT205286 STK11IP serine/threonine kinase 11 interacting protein 2 2
MIRT206051 PPARA peroxisome proliferator activated receptor alpha 2 2
MIRT206198 RAB10 RAB10, member RAS oncogene family 2 4
MIRT208980 SKIL SKI like proto-oncogene 2 10
MIRT223637 ATP6V1C1 ATPase H+ transporting V1 subunit C1 2 4
MIRT224757 DPYSL2 dihydropyrimidinase like 2 2 2
MIRT227995 NFIB nuclear factor I B 2 4
MIRT230973 PRRG4 proline rich and Gla domain 4 2 2
MIRT238183 ANKRD33B ankyrin repeat domain 33B 2 10
MIRT242425 HAS3 hyaluronan synthase 3 2 2
MIRT242666 SALL3 spalt like transcription factor 3 2 4
MIRT242765 FNBP1L formin binding protein 1 like 2 6
MIRT243095 LCLAT1 lysocardiolipin acyltransferase 1 2 4
MIRT243437 PAK2 p21 (RAC1) activated kinase 2 2 2
MIRT243964 MAP1B microtubule associated protein 1B 2 2
MIRT244776 RABGAP1 RAB GTPase activating protein 1 2 2
MIRT246630 TMEM109 transmembrane protein 109 2 2
MIRT246968 TSKU tsukushi, small leucine rich proteoglycan 2 2
MIRT266055 FJX1 four jointed box 1 2 4
MIRT266858 SLC25A44 solute carrier family 25 member 44 2 2
MIRT283184 C16ORF52 chromosome 16 open reading frame 52 2 2
MIRT286955 SOCS7 suppressor of cytokine signaling 7 2 2
MIRT293651 PVR poliovirus receptor 2 4
MIRT295178 ZNF317 zinc finger protein 317 2 4
MIRT302453 CLIP4 CAP-Gly domain containing linker protein family member 4 2 2
MIRT303499 NAGK N-acetylglucosamine kinase 2 6
MIRT368755 CDADC1 cytidine and dCMP deaminase domain containing 1 2 2
MIRT383207 APH1A aph-1 homolog A, gamma-secretase subunit 2 2
MIRT383610 POU2F1 POU class 2 homeobox 1 2 2
MIRT396102 CASP2 caspase 2 2 2
MIRT441419 FAM9C family with sequence similarity 9 member C 2 2
MIRT446818 C5orf30 chromosome 5 open reading frame 30 2 2
MIRT448307 WNK3 WNK lysine deficient protein kinase 3 2 2
MIRT461781 MPDU1 mannose-P-dolichol utilization defect 1 2 2
MIRT462816 NTN1 netrin 1 2 2
MIRT463613 ZBTB34 zinc finger and BTB domain containing 34 2 2
MIRT464560 UBTF upstream binding transcription factor, RNA polymerase I 2 2
MIRT464842 RPS27A ribosomal protein S27a 2 12
MIRT465225 TRIP10 thyroid hormone receptor interactor 10 2 2
MIRT466446 TFAM transcription factor A, mitochondrial 2 8
MIRT466836 STX6 syntaxin 6 2 6
MIRT467185 SPTY2D1 SPT2 chromatin protein domain containing 1 2 2
MIRT468179 SGMS1 sphingomyelin synthase 1 2 2
MIRT469850 PXK PX domain containing serine/threonine kinase like 2 8
MIRT471612 PAQR5 progestin and adipoQ receptor family member 5 2 19
MIRT472008 NR1D2 nuclear receptor subfamily 1 group D member 2 2 2
MIRT472159 NIN ninein 2 4
MIRT472336 NETO2 neuropilin and tolloid like 2 2 4
MIRT473162 MLLT1 MLLT1, super elongation complex subunit 2 2
MIRT473623 MARK2 microtubule affinity regulating kinase 2 2 2
MIRT473682 MAPKBP1 mitogen-activated protein kinase binding protein 1 2 2
MIRT473805 MAP3K2 mitogen-activated protein kinase kinase kinase 2 2 2
MIRT474416 KLHL28 kelch like family member 28 2 8
MIRT474736 KIF13A kinesin family member 13A 2 6
MIRT474966 KCTD10 potassium channel tetramerization domain containing 10 2 4
MIRT475464 HSPA8 heat shock protein family A (Hsp70) member 8 2 6
MIRT476120 GPR157 G protein-coupled receptor 157 2 2
MIRT476203 GNS glucosamine (N-acetyl)-6-sulfatase 2 6
MIRT477180 F3 coagulation factor III, tissue factor 2 8
MIRT478103 DLG5 discs large MAGUK scaffold protein 5 2 6
MIRT478713 CSNK1A1 casein kinase 1 alpha 1 2 6
MIRT479055 CNOT6L CCR4-NOT transcription complex subunit 6 like 2 8
MIRT480008 CAPRIN2 caprin family member 2 2 4
MIRT480519 C11orf30 EMSY, BRCA2 interacting transcriptional repressor 2 10
MIRT480822 BLCAP bladder cancer associated protein 2 10
MIRT480944 BBX BBX, HMG-box containing 2 8
MIRT481336 ATL3 atlastin GTPase 3 2 2
MIRT481598 ARHGAP1 Rho GTPase activating protein 1 2 6
MIRT481877 ANKRD50 ankyrin repeat domain 50 2 2
MIRT482471 ADAR adenosine deaminase, RNA specific 2 4
MIRT484875 ZNF652 zinc finger protein 652 2 2
MIRT485090 SLC30A1 solute carrier family 30 member 1 2 4
MIRT485579 FOXQ1 forkhead box Q1 2 2
MIRT485618 FBXL5 F-box and leucine rich repeat protein 5 2 10
MIRT486751 CNOT4 CCR4-NOT transcription complex subunit 4 2 6
MIRT489599 ZDHHC20 zinc finger DHHC-type containing 20 2 10
MIRT489889 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT491654 PDRG1 p53 and DNA damage regulated 1 2 10
MIRT492038 TSG101 tumor susceptibility 101 2 4
MIRT492361 SEMA7A semaphorin 7A (John Milton Hagen blood group) 2 2
MIRT492776 PDGFB platelet derived growth factor subunit B 2 2
MIRT493336 LAPTM4A lysosomal protein transmembrane 4 alpha 2 12
MIRT493611 HMGB3 high mobility group box 3 2 6
MIRT497468 DDR2 discoidin domain receptor tyrosine kinase 2 2 2
MIRT498059 SNX5 sorting nexin 5 2 6
MIRT499901 KIAA1191 KIAA1191 2 4
MIRT500489 ZBTB4 zinc finger and BTB domain containing 4 2 6
MIRT500685 TRIM37 tripartite motif containing 37 2 2
MIRT500760 TMEM127 transmembrane protein 127 2 6
MIRT501456 PTPN4 protein tyrosine phosphatase, non-receptor type 4 2 8
MIRT501559 POC1B-GALNT4 POC1B-GALNT4 readthrough 2 2
MIRT501983 MAPK1 mitogen-activated protein kinase 1 2 10
MIRT502000 MAP7 microtubule associated protein 7 2 8
MIRT502049 LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 2 6
MIRT502423 GALNT4 polypeptide N-acetylgalactosaminyltransferase 4 2 2
MIRT503044 CAMSAP2 calmodulin regulated spectrin associated protein family member 2 2 2
MIRT503821 TMEM242 transmembrane protein 242 2 4
MIRT504290 PARP1 poly(ADP-ribose) polymerase 1 2 6
MIRT504560 ZNF417 zinc finger protein 417 2 6
MIRT505054 ZNF202 zinc finger protein 202 2 6
MIRT505486 SRSF2 serine and arginine rich splicing factor 2 2 4
MIRT505836 POLR1B RNA polymerase I subunit B 2 4
MIRT506372 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 4
MIRT506451 NACC2 NACC family member 2 2 4
MIRT506673 LZIC leucine zipper and CTNNBIP1 domain containing 2 4
MIRT506834 KIF23 kinesin family member 23 2 4
MIRT506880 KIAA0101 PCNA clamp associated factor 2 6
MIRT507359 FAM129A family with sequence similarity 129 member A 2 6
MIRT507957 BNIP2 BCL2 interacting protein 2 2 6
MIRT509433 MCM7 minichromosome maintenance complex component 7 2 6
MIRT510872 RAN RAN, member RAS oncogene family 2 8
MIRT511078 NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 2 4
MIRT511254 KLHL36 kelch like family member 36 2 6
MIRT513699 RBM20 RNA binding motif protein 20 2 4
MIRT513742 PKNOX1 PBX/knotted 1 homeobox 1 2 2
MIRT513981 CEP97 centrosomal protein 97 2 2
MIRT514092 EPS15L1 epidermal growth factor receptor pathway substrate 15 like 1 2 6
MIRT515928 MFAP2 microfibril associated protein 2 2 4
MIRT519574 ZNFX1 zinc finger NFX1-type containing 1 2 4
MIRT521297 RRAGD Ras related GTP binding D 2 4
MIRT521348 RPP14 ribonuclease P/MRP subunit p14 2 2
MIRT521693 PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 2 8
MIRT521778 PPIG peptidylprolyl isomerase G 2 8
MIRT522191 NR2C2 nuclear receptor subfamily 2 group C member 2 2 6
MIRT524696 BTG3 BTG anti-proliferation factor 3 2 8
MIRT525663 NHSL2 NHS like 2 2 2
MIRT527252 TMEM196 transmembrane protein 196 2 2
MIRT527466 CLEC12B C-type lectin domain family 12 member B 2 2
MIRT529535 ICMT isoprenylcysteine carboxyl methyltransferase 2 2
MIRT530146 HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2 2
MIRT530851 RAG1 recombination activating 1 2 4
MIRT531109 PEX13 peroxisomal biogenesis factor 13 2 2
MIRT534263 SLC12A7 solute carrier family 12 member 7 2 2
MIRT534756 RASGEF1A RasGEF domain family member 1A 2 2
MIRT535175 PLEKHB2 pleckstrin homology domain containing B2 2 2
MIRT535246 PIGA phosphatidylinositol glycan anchor biosynthesis class A 2 4
MIRT535401 PER1 period circadian clock 1 2 2
MIRT536036 MCUR1 mitochondrial calcium uniporter regulator 1 2 2
MIRT536347 LEFTY1 left-right determination factor 1 2 2
MIRT536413 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT536437 KMT2B lysine methyltransferase 2B 2 6
MIRT536604 IRF2 interferon regulatory factor 2 2 2
MIRT536642 INO80D INO80 complex subunit D 2 2
MIRT536860 HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 2 2
MIRT537241 GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 2 2
MIRT537728 ELAVL2 ELAV like RNA binding protein 2 2 2
MIRT537988 DPP8 dipeptidyl peptidase 8 2 2
MIRT538037 DNAJB6 DnaJ heat shock protein family (Hsp40) member B6 2 2
MIRT538255 CUL3 cullin 3 2 4
MIRT538525 CLCN3 chloride voltage-gated channel 3 2 2
MIRT538659 CCSAP centriole, cilia and spindle associated protein 2 2
MIRT538779 C7orf60 base methyltransferase of 25S rRNA 2 homolog 2 4
MIRT538849 BTG1 BTG anti-proliferation factor 1 2 2
MIRT538923 BRI3BP BRI3 binding protein 2 6
MIRT539114 ARL10 ADP ribosylation factor like GTPase 10 2 2
MIRT539454 ADARB2 adenosine deaminase, RNA specific B2 (inactive) 2 2
MIRT541085 RLIM ring finger protein, LIM domain interacting 2 2
MIRT543117 SKA2 spindle and kinetochore associated complex subunit 2 2 2
MIRT543181 FICD FIC domain containing 2 2
MIRT543575 RPF2 ribosome production factor 2 homolog 2 4
MIRT544113 IPMK inositol polyphosphate multikinase 2 2
MIRT544625 CSDE1 cold shock domain containing E1 2 2
MIRT544699 ZNF224 zinc finger protein 224 2 4
MIRT544992 MFF mitochondrial fission factor 2 4
MIRT546248 TNFRSF21 TNF receptor superfamily member 21 2 2
MIRT546282 TMEM30A transmembrane protein 30A 2 4
MIRT546290 TMEM200C transmembrane protein 200C 2 4
MIRT546558 SATB2 SATB homeobox 2 2 2
MIRT546815 RAP2C RAP2C, member of RAS oncogene family 2 2
MIRT547046 POGZ pogo transposable element derived with ZNF domain 2 2
MIRT547474 MBNL3 muscleblind like splicing regulator 3 2 4
MIRT547761 KATNAL1 katanin catalytic subunit A1 like 1 2 2
MIRT547892 HSPA13 heat shock protein family A (Hsp70) member 13 2 2
MIRT548315 EPHA4 EPH receptor A4 2 2
MIRT548383 ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 2 4
MIRT548460 EGLN3 egl-9 family hypoxia inducible factor 3 2 2
MIRT548579 DNAJB14 DnaJ heat shock protein family (Hsp40) member B14 2 2
MIRT548858 CERCAM cerebral endothelial cell adhesion molecule 2 2
MIRT548896 CHEK2 checkpoint kinase 2 2 4
MIRT549319 ARHGAP12 Rho GTPase activating protein 12 2 4
MIRT550302 ZNF681 zinc finger protein 681 2 2
MIRT551120 ZNF107 zinc finger protein 107 2 2
MIRT551406 DCTPP1 dCTP pyrophosphatase 1 2 2
MIRT552173 DAD1 defender against cell death 1 2 2
MIRT552856 WIPF2 WAS/WASL interacting protein family member 2 2 2
MIRT552892 WASL Wiskott-Aldrich syndrome like 2 4
MIRT553075 UEVLD UEV and lactate/malate dehyrogenase domains 2 2
MIRT553668 TFAP4 transcription factor AP-4 2 4
MIRT553700 TCF7L2 transcription factor 7 like 2 2 2
MIRT554608 RPS6KA5 ribosomal protein S6 kinase A5 2 2
MIRT554860 RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 2 2
MIRT556157 MECP2 methyl-CpG binding protein 2 2 2
MIRT556179 MCC mutated in colorectal cancers 2 2
MIRT556529 LIN52 lin-52 DREAM MuvB core complex component 2 2
MIRT556723 KLHL21 kelch like family member 21 2 4
MIRT557054 HOXB3 homeobox B3 2 2
MIRT557587 GNPTAB N-acetylglucosamine-1-phosphate transferase alpha and beta subunits 2 2
MIRT557661 GATA6 GATA binding protein 6 2 2
MIRT557753 FRS2 fibroblast growth factor receptor substrate 2 2 2
MIRT557881 FEM1B fem-1 homolog B 2 4
MIRT558215 EFCAB14 EF-hand calcium binding domain 14 2 4
MIRT558264 DYNC1LI2 dynein cytoplasmic 1 light intermediate chain 2 2 2
MIRT558327 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 4
MIRT558766 CFL2 cofilin 2 2 2
MIRT561037 ASB6 ankyrin repeat and SOCS box containing 6 2 2
MIRT561324 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT561641 RUNX3 runt related transcription factor 3 2 2
MIRT562555 CCDC71L coiled-coil domain containing 71 like 2 4
MIRT562961 LRPAP1 LDL receptor related protein associated protein 1 2 2
MIRT564680 ZNF35 zinc finger protein 35 2 2
MIRT565694 SESN3 sestrin 3 2 2
MIRT565910 SCAMP2 secretory carrier membrane protein 2 2 2
MIRT566141 RACGAP1 Rac GTPase activating protein 1 2 2
MIRT567047 KCNB1 potassium voltage-gated channel subfamily B member 1 2 2
MIRT567076 KBTBD2 kelch repeat and BTB domain containing 2 2 2
MIRT567539 FGFR1OP FGFR1 oncogene partner 2 2
MIRT567624 FAM210A family with sequence similarity 210 member A 2 2
MIRT570321 ZNF70 zinc finger protein 70 2 2
MIRT571759 PSD3 pleckstrin and Sec7 domain containing 3 2 2
MIRT571857 NKIRAS1 NFKB inhibitor interacting Ras like 1 2 2
MIRT573372 LIMA1 LIM domain and actin binding 1 2 2
MIRT574561 NR2F2 nuclear receptor subfamily 2 group F member 2 2 2
MIRT614729 ATAT1 alpha tubulin acetyltransferase 1 2 4
MIRT617877 ESR1 estrogen receptor 1 2 2
MIRT624421 CBX8 chromobox 8 2 2
MIRT625865 SLC35C2 solute carrier family 35 member C2 2 2
MIRT630703 DICER1 dicer 1, ribonuclease III 2 4
MIRT632514 PTPN9 protein tyrosine phosphatase, non-receptor type 9 2 2
MIRT641797 USP32 ubiquitin specific peptidase 32 2 2
MIRT663625 SEC23B Sec23 homolog B, coat complex II component 2 2
MIRT680135 ADRBK2 G protein-coupled receptor kinase 3 2 2
MIRT702388 KLF10 Kruppel like factor 10 2 2
MIRT707830 TMEM133 transmembrane protein 133 2 2
MIRT708885 MOCS2 molybdenum cofactor synthesis 2 2 2
MIRT709122 C3orf18 chromosome 3 open reading frame 18 2 2
MIRT709635 KBTBD6 kelch repeat and BTB domain containing 6 2 2
MIRT710596 CDCA4 cell division cycle associated 4 2 2
MIRT710802 IFNLR1 interferon lambda receptor 1 2 2
MIRT711782 RFXAP regulatory factor X associated protein 2 2
MIRT713344 KLRD1 killer cell lectin like receptor D1 2 2
MIRT713640 MED8 mediator complex subunit 8 2 2
MIRT713916 IGF2R insulin like growth factor 2 receptor 2 2
MIRT715068 TMTC1 transmembrane and tetratricopeptide repeat containing 1 2 2
MIRT715206 FKTN fukutin 2 2
MIRT717819 FAM114A1 family with sequence similarity 114 member A1 2 2
MIRT720543 CHERP calcium homeostasis endoplasmic reticulum protein 2 2
MIRT720636 ELF5 E74 like ETS transcription factor 5 2 2
MIRT721703 ISY1 ISY1 splicing factor homolog 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-519c Bilobalide NULL 73581 Quantitative real-time PCR Human breast cancer MCF-7 cells 21796641 2011 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-519c Docetaxel+Cisplatin+5-Fluorouracil resistant tissue (hypopharyngeal squamous cell carcinoma)
hsa-miR-519c-3p Mitoxantrone 4212 NSC279836 approved sensitive Low Breast Cancer cell line (MCF-7)
hsa-miR-519c-3p Cisplatin 5460033 NSC119875 approved resistant High Germ Cell Tumor cell line (NTERA-2)
hsa-miR-519c-3p Vinorelbine 44424639 approved resistant High Non-Small Cell Lung Cancer cell line (H358, H1993)
hsa-miR-519c-3p Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-519c-3p Gemcitabine 60750 NSC613327 approved sensitive Low Pancreatic Cancer cell line (MIA-PaCa-2)
hsa-miR-519c-3p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-519c-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)
hsa-miR-519c-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM36)
hsa-miR-519c-3p Fluorouracil 3385 NSC19893 approved resistant cell line (KM12C) (72 h)
hsa-miR-519c-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-miR-519c-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

Error report submission