miRTarBase - #MIRT069388


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pre-miRNA Information
pre-miRNA hsa-mir-367   
Genomic Coordinates chr4: 112647874 - 112647941
Synonyms MIRN367, hsa-mir-367, MIR367
Description Homo sapiens miR-367 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-367-3p
Sequence 44| AAUUGCACUUUAGCAAUGGUGA |65
Evidence Experimental
Experiments Cloned
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN24411246 17 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs535597757 1 dbSNP
rs1013348949 11 dbSNP
rs896333735 12 dbSNP
rs751269136 14 dbSNP
rs1163501507 16 dbSNP
rs757092597 21 dbSNP
Putative Targets

Gene Information
Gene Symbol ZFYVE21   
Synonyms HCVP7TP1, ZF21
Description zinc finger FYVE-type containing 21
Transcript NM_024071   
Expression
Putative miRNA Targets on ZFYVE21
3'UTR of ZFYVE21
(miRNA target sites are highlighted)		 
>ZFYVE21|NM_024071|3'UTR
   1 CTCTACGTGGGGCTGAGCTTGGAGTACGTGTGGTCACCAGGACTGAGTCGCTTGGAACAGCAGAGCCTGCTCCTTGCGTA
  81 CCACAGGGATTAATCCTGCTTGTGCTGGGAAATGCAACTCACTCATGTATTTGGAGAAACAGGAGTGTTCACTTATCTAG
 161 TGCAATATGTTCACAGTTTATTAATGCTTTAAACAGCTTCATGTTTTAGAATTTGTGTATTGTCAATACTTAATTGGGGG
 241 TGGGAGAGACTGAGCTACACTACTGCTAAACTATTTTTAGCATAATATATACCATTTTTATGAGTTCGCAGGTCTACTAG
 321 AAGGTTCTGGCCCATCAATATTCATTTCATTTAATTCTTCCACAGAACCAGTTTGGGCAGTAGGAACTCAGGCTTCTGGT
 401 CTGCAGTGGAGCCTGTTCGCCTCTAATAGCCAGTTTACAGCACTTGCCTTAGCCTGTTTCACAGACTTGTCCACTTACCT
 481 TGTCACTAATTTGGGGCTTCTGGGCTGTGAGTGATCCTTTGATACTTCACCAAGGGGAACGTGGGGGCTTTGTGTTTTGT
 561 ACTTTTCACTCACTATTTCACTTTATTAAGATGACTGTACAGCAATTTGTATATAAAGCTTATGATTAAAAACTATTTTG
 641 AACATACGGAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aguGGUAACGAUUUCACGUUAa 5'
             :|| |  |  |||||||| 
Target 5' tgtTCACTTATCTAGTGCAATa 3'
 146 - 167 151.00 -10.80
2 
miRNA  3' agUGGUAACGA--UUUCACGUUaa 5'
            :|:  ||||  :|| |||||  
Target 5' ctGCTTGTGCTGGGAAATGCAAct 3'
 96 - 119 110.00 -7.50
3 
miRNA  3' aguGGUA-ACGAUUU----CACGUUAa 5'
             :||| | :||:|    |||:| | 
Target 5' gctTCATGTTTTAGAATTTGTGTATTg 3'
 196 - 222 105.00 -5.12
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN164793 2 COSMIC
COSN30491707 11 COSMIC
COSN30517255 16 COSMIC
COSN30473267 23 COSMIC
COSN26602641 31 COSMIC
COSN13572718 47 COSMIC
COSN27005712 80 COSMIC
COSN24998162 92 COSMIC
COSN19693336 106 COSMIC
COSN20111734 142 COSMIC
COSN28528724 166 COSMIC
COSN31609321 184 COSMIC
COSN20077984 199 COSMIC
COSN24295424 226 COSMIC
COSN31483389 269 COSMIC
COSN30120513 308 COSMIC
COSN31530696 317 COSMIC
COSN30540312 321 COSMIC
COSN31533973 364 COSMIC
COSN1638546 426 COSMIC
COSN31538884 534 COSMIC
COSN22358693 586 COSMIC
COSN29333348 636 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs780441491 1 dbSNP
rs2295146 2 dbSNP
rs774395784 4 dbSNP
rs762276886 6 dbSNP
rs767751377 7 dbSNP
rs566285060 8 dbSNP
rs535176908 12 dbSNP
rs1208422668 13 dbSNP
rs968510369 16 dbSNP
rs1264432464 17 dbSNP
rs747251034 17 dbSNP
rs1331917494 20 dbSNP
rs766922840 22 dbSNP
rs113873376 25 dbSNP
rs768935839 27 dbSNP
rs907618430 28 dbSNP
rs754491974 29 dbSNP
rs1468275969 33 dbSNP
rs1176178543 35 dbSNP
rs1034041103 38 dbSNP
rs774196171 39 dbSNP
rs1473246950 42 dbSNP
rs1174224316 45 dbSNP
rs768646317 48 dbSNP
rs571350084 50 dbSNP
rs758266464 51 dbSNP
rs1281471941 54 dbSNP
rs1289625276 55 dbSNP
rs916912179 61 dbSNP
rs1228127268 66 dbSNP
rs905667686 78 dbSNP
rs1337512806 79 dbSNP
rs1001333883 86 dbSNP
rs536676598 97 dbSNP
rs1197382587 99 dbSNP
rs1057409341 102 dbSNP
rs895754680 106 dbSNP
rs1013990246 108 dbSNP
rs1262898193 117 dbSNP
rs1020986453 122 dbSNP
rs1450507436 123 dbSNP
rs966781220 124 dbSNP
rs150670962 126 dbSNP
rs972959108 128 dbSNP
rs1032436165 135 dbSNP
rs143367739 137 dbSNP
rs777799245 137 dbSNP
rs1231014914 144 dbSNP
rs1295996777 153 dbSNP
rs974957551 153 dbSNP
rs573896256 157 dbSNP
rs955014102 161 dbSNP
rs1048527730 166 dbSNP
rs1181116321 172 dbSNP
rs138869791 174 dbSNP
rs983516828 187 dbSNP
rs1171288773 191 dbSNP
rs1462876841 192 dbSNP
rs1162660903 196 dbSNP
rs552803888 199 dbSNP
rs781143078 202 dbSNP
rs911269450 202 dbSNP
rs1389983892 211 dbSNP
rs1410558855 213 dbSNP
rs1477079605 214 dbSNP
rs1260519753 217 dbSNP
rs572721479 218 dbSNP
rs544768785 222 dbSNP
rs941704979 223 dbSNP
rs8548 226 dbSNP
rs1334140765 227 dbSNP
rs771031911 227 dbSNP
rs112502838 236 dbSNP
rs774491958 237 dbSNP
rs1344175116 241 dbSNP
rs1056991868 246 dbSNP
rs1220220266 251 dbSNP
rs1357756481 260 dbSNP
rs895712516 261 dbSNP
rs946024220 269 dbSNP
rs578027707 272 dbSNP
rs1034072253 280 dbSNP
rs902481271 286 dbSNP
rs759820189 288 dbSNP
rs1333966995 290 dbSNP
rs149377639 291 dbSNP
rs1340721914 293 dbSNP
rs1423394276 294 dbSNP
rs111730222 309 dbSNP
rs867257673 313 dbSNP
rs1369875209 317 dbSNP
rs1274516239 328 dbSNP
rs1435627101 331 dbSNP
rs1441392966 331 dbSNP
rs961722105 332 dbSNP
rs972993343 337 dbSNP
rs529230471 339 dbSNP
rs1257833631 342 dbSNP
rs1358734537 344 dbSNP
rs918819299 354 dbSNP
rs1244082680 358 dbSNP
rs564171822 365 dbSNP
rs1312046571 369 dbSNP
rs1445243855 370 dbSNP
rs952859417 376 dbSNP
rs1476050547 377 dbSNP
rs775993328 385 dbSNP
rs1326955539 386 dbSNP
rs900612256 387 dbSNP
rs1392410409 389 dbSNP
rs984253796 396 dbSNP
rs1058080 397 dbSNP
rs996736402 412 dbSNP
rs1030534662 413 dbSNP
rs955128211 419 dbSNP
rs1394407664 420 dbSNP
rs1429265597 425 dbSNP
rs1313681796 428 dbSNP
rs983683958 428 dbSNP
rs1453126686 430 dbSNP
rs1377555507 435 dbSNP
rs1413279231 437 dbSNP
rs367637650 439 dbSNP
rs1327471548 446 dbSNP
rs761059448 448 dbSNP
rs962988959 452 dbSNP
rs973063833 456 dbSNP
rs1041122324 461 dbSNP
rs1248565519 467 dbSNP
rs1304880035 470 dbSNP
rs1329711376 473 dbSNP
rs1438975565 473 dbSNP
rs1230243888 477 dbSNP
rs922608167 480 dbSNP
rs1360819216 483 dbSNP
rs1159931565 486 dbSNP
rs946029977 494 dbSNP
rs1268996943 497 dbSNP
rs1191710430 505 dbSNP
rs1041621933 506 dbSNP
rs904416777 508 dbSNP
rs927030836 514 dbSNP
rs1447766165 524 dbSNP
rs1055590294 527 dbSNP
rs937138614 534 dbSNP
rs1280534367 535 dbSNP
rs993066626 538 dbSNP
rs543345247 541 dbSNP
rs1014446583 542 dbSNP
rs1432019214 548 dbSNP
rs1340731303 549 dbSNP
rs1198450590 553 dbSNP
rs1024026173 554 dbSNP
rs560054899 566 dbSNP
rs962032253 566 dbSNP
rs993123757 570 dbSNP
rs1255238523 574 dbSNP
rs1447427372 576 dbSNP
rs755629019 592 dbSNP
rs1371306301 596 dbSNP
rs1423024363 598 dbSNP
rs45614733 600 dbSNP
rs1041627310 603 dbSNP
rs750264981 608 dbSNP
rs1174370357 610 dbSNP
rs180907718 612 dbSNP
rs571414009 616 dbSNP
rs984354961 618 dbSNP
rs936637896 624 dbSNP
rs1212389117 625 dbSNP
rs1441193304 627 dbSNP
rs1302544699 634 dbSNP
rs764841028 639 dbSNP
rs1320452165 642 dbSNP
rs749983911 643 dbSNP
rs1386124466 646 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 79038.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aguGGUAACGAUUUCACGUUAa 5'
             :|| |  |  |||||||| 
Target 5' --uUCACUUAUCUAGUGCAAUa 3'
 		1 - 20
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000216602.6 | 3UTR | UUCACUUAUCUAGUGCAAUAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer 0.607 8.3e-4 0.665 2.0e-4 24 Click to see details
GSE32688 Pancreatic cancer 0.443 5.6e-3 0.509 1.5e-3 32 Click to see details
GSE28260 Renal cortex and medulla 0.501 4.1e-2 0.482 4.8e-2 13 Click to see details
GSE14794 Lymphoblastoid cells -0.122 1.3e-1 -0.146 8.5e-2 90 Click to see details
GSE17306 Multiple myeloma 0.145 1.6e-1 0.454 5.3e-4 49 Click to see details
GSE19350 CNS germ cell tumors 0.292 1.8e-1 0.455 6.9e-2 12 Click to see details
GSE42095 Differentiated embryonic stem cells 0.2 1.8e-1 0.186 2.0e-1 23 Click to see details
GSE15076 Monocyte-derived dendritic cells -0.52 1.8e-1 -0.500 2.0e-1 5 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.179 2.0e-1 -0.160 2.2e-1 25 Click to see details
GSE21687 Ependynoma primary tumors 0.105 2.0e-1 0.150 1.2e-1 64 Click to see details
GSE21849 B cell lymphoma 0.147 2.2e-1 0.521 1.9e-3 29 Click to see details
GSE27834 Pluripotent stem cells -0.175 2.6e-1 -0.232 1.9e-1 16 Click to see details
GSE17498 Multiple myeloma -0.082 3.1e-1 0.004 4.9e-1 40 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.107 3.3e-1 -0.030 4.5e-1 20 Click to see details
GSE38226 Liver fibrosis -0.099 3.3e-1 -0.069 3.8e-1 21 Click to see details
GSE26953 Aortic valvular endothelial cells 0.079 3.6e-1 0.095 3.3e-1 24 Click to see details
GSE26953 Aortic valvular endothelial cells 0.079 3.6e-1 0.095 3.3e-1 24 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
255 hsa-miR-367-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055315 DUSP5 dual specificity phosphatase 5 2 8
MIRT055791 PLEKHA1 pleckstrin homology domain containing A1 2 12
MIRT057114 DDIT4 DNA damage inducible transcript 4 2 4
MIRT059663 GATAD2B GATA zinc finger domain containing 2B 2 2
MIRT059926 ZDHHC5 zinc finger DHHC-type containing 5 2 2
MIRT061610 BTG2 BTG anti-proliferation factor 2 2 6
MIRT066478 HMGA2 high mobility group AT-hook 2 2 2
MIRT069388 ZFYVE21 zinc finger FYVE-type containing 21 2 2
MIRT069972 GEMIN2 gem nuclear organelle associated protein 2 2 2
MIRT074764 CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 2 2
MIRT076199 GID4 GID complex subunit 4 homolog 2 6
MIRT077512 UBE2Z ubiquitin conjugating enzyme E2 Z 2 4
MIRT077903 TOB1 transducer of ERBB2, 1 2 6
MIRT082250 MED29 mediator complex subunit 29 2 4
MIRT082434 CIC capicua transcriptional repressor 2 6
MIRT082474 PPP1R37 protein phosphatase 1 regulatory subunit 37 2 2
MIRT082778 ZNF264 zinc finger protein 264 2 2
MIRT084533 BCL2L11 BCL2 like 11 2 8
MIRT085309 UBXN4 UBX domain protein 4 2 8
MIRT086365 SSFA2 sperm specific antigen 2 2 8
MIRT087455 NF2 neurofibromin 2 2 2
MIRT088865 FOXN2 forkhead box N2 2 12
MIRT092185 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 2 6
MIRT092326 EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 2 6
MIRT093533 GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 2 6
MIRT096935 PAPD7 poly(A) RNA polymerase D7, non-canonical 2 8
MIRT097026 MAP1B microtubule associated protein 1B 2 4
MIRT099137 MYLIP myosin regulatory light chain interacting protein 2 6
MIRT099905 SOX4 SRY-box 4 2 12
MIRT102289 DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 2 10
MIRT102507 KLHDC10 kelch domain containing 10 2 2
MIRT102891 INSIG1 insulin induced gene 1 2 2
MIRT109188 VMA21 VMA21, vacuolar ATPase assembly factor 2 4
MIRT124567 PRRC2B proline rich coiled-coil 2B 2 2
MIRT135568 SPRYD4 SPRY domain containing 4 2 2
MIRT161135 SLC25A36 solute carrier family 25 member 36 2 6
MIRT163995 KIAA1109 KIAA1109 2 4
MIRT164689 RNF4 ring finger protein 4 2 2
MIRT167705 HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 2 8
MIRT178956 USP28 ubiquitin specific peptidase 28 2 2
MIRT185717 ARNTL2 aryl hydrocarbon receptor nuclear translocator like 2 2 2
MIRT186264 TCEB3 elongin A 2 2
MIRT186537 TWF1 twinfilin actin binding protein 1 2 4
MIRT186628 COX20 COX20, cytochrome c oxidase assembly factor 2 8
MIRT189373 TXLNA taxilin alpha 2 4
MIRT197013 EIF1 eukaryotic translation initiation factor 1 2 10
MIRT206437 YIPF4 Yip1 domain family member 4 2 2
MIRT211228 FGF2 fibroblast growth factor 2 2 10
MIRT214529 C5ORF24 chromosome 5 open reading frame 24 2 2
MIRT216034 IL6ST interleukin 6 signal transducer 2 10
MIRT218084 TULP4 tubby like protein 4 2 2
MIRT242418 CCDC113 coiled-coil domain containing 113 2 2
MIRT243162 SOX11 SRY-box 11 2 2
MIRT250943 CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 2 4
MIRT253350 ZNF417 zinc finger protein 417 2 2
MIRT271968 ARF1 ADP ribosylation factor 1 2 2
MIRT273214 ZNF695 zinc finger protein 695 2 4
MIRT296114 SLC12A5 solute carrier family 12 member 5 2 2
MIRT301711 TEF TEF, PAR bZIP transcription factor 2 2
MIRT316477 ARID1B AT-rich interaction domain 1B 2 6
MIRT322174 CLN8 CLN8, transmembrane ER and ERGIC protein 2 4
MIRT341538 CNIH1 cornichon family AMPA receptor auxiliary protein 1 2 6
MIRT356062 SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 2 2
MIRT443579 PPIC peptidylprolyl isomerase C 2 2
MIRT448825 FKBP1A FK506 binding protein 1A 2 4
MIRT451494 FOPNL FGFR1OP N-terminal like 2 2
MIRT452694 MDM2 MDM2 proto-oncogene 2 2
MIRT453167 CNOT4 CCR4-NOT transcription complex subunit 4 2 6
MIRT454588 SLC33A1 solute carrier family 33 member 1 2 4
MIRT455794 TAF8 TATA-box binding protein associated factor 8 2 4
MIRT456010 CYP2C19 cytochrome P450 family 2 subfamily C member 19 2 2
MIRT456044 KIAA1586 KIAA1586 2 2
MIRT456763 TMEM239 transmembrane protein 239 2 4
MIRT458068 NLRP9 NLR family pyrin domain containing 9 2 2
MIRT459230 MRPS21 mitochondrial ribosomal protein S21 2 2
MIRT459534 MFF mitochondrial fission factor 2 6
MIRT459759 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT460236 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT461104 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT462924 ZNRF3 zinc and ring finger 3 2 2
MIRT463476 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT463516 ZBTB8B zinc finger and BTB domain containing 8B 2 4
MIRT465503 TOR1B torsin family 1 member B 2 2
MIRT469525 RBFOX2 RNA binding protein, fox-1 homolog 2 2 8
MIRT470079 PTGES2 prostaglandin E synthase 2 2 2
MIRT471581 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT473451 MCOLN2 mucolipin 2 2 8
MIRT475882 H3F3C H3 histone family member 3C 2 10
MIRT475915 H3F3B H3 histone family member 3B 2 8
MIRT476195 GOLGA8A golgin A8 family member A 2 10
MIRT476318 GM2A GM2 ganglioside activator 2 2
MIRT476676 FUT11 fucosyltransferase 11 2 10
MIRT478368 DDI2 DNA damage inducible 1 homolog 2 2 2
MIRT479545 CDC5L cell division cycle 5 like 2 2
MIRT481024 BAZ2B bromodomain adjacent to zinc finger domain 2B 2 2
MIRT491009 ATF7IP activating transcription factor 7 interacting protein 2 2
MIRT493168 MKNK2 MAP kinase interacting serine/threonine kinase 2 2 2
MIRT494345 CASKIN1 CASK interacting protein 1 2 2
MIRT499087 ZDHHC21 zinc finger DHHC-type containing 21 2 6
MIRT500029 ABCF2 ATP binding cassette subfamily F member 2 2 8
MIRT501298 RRN3 RRN3 homolog, RNA polymerase I transcription factor 2 4
MIRT503124 BCL11B B-cell CLL/lymphoma 11B 2 8
MIRT503301 GTF2A1 general transcription factor IIA subunit 1 2 6
MIRT504328 ASGR2 asialoglycoprotein receptor 2 2 6
MIRT504471 EID2B EP300 interacting inhibitor of differentiation 2B 2 2
MIRT504655 RPL9 ribosomal protein L9 2 6
MIRT505331 TMF1 TATA element modulatory factor 1 2 8
MIRT505732 SERTAD3 SERTA domain containing 3 2 4
MIRT505827 RSBN1 round spermatid basic protein 1 2 8
MIRT506004 PURG purine rich element binding protein G 2 8
MIRT506308 PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 2 6
MIRT506806 KLHL15 kelch like family member 15 2 6
MIRT507119 GOLGA8B golgin A8 family member B 2 6
MIRT507353 FAM129A family with sequence similarity 129 member A 2 6
MIRT507591 DDX3X DEAD-box helicase 3, X-linked 2 4
MIRT507674 CPEB4 cytoplasmic polyadenylation element binding protein 4 2 4
MIRT507703 CNOT2 CCR4-NOT transcription complex subunit 2 2 8
MIRT508012 BCAT1 branched chain amino acid transaminase 1 2 4
MIRT510439 ZIC5 Zic family member 5 2 6
MIRT510539 XKR7 XK related 7 2 4
MIRT510600 TPPP tubulin polymerization promoting protein 2 6
MIRT511060 NRAS NRAS proto-oncogene, GTPase 2 4
MIRT511855 GOLGA8J golgin A8 family member J 2 6
MIRT511865 GOLGA8I golgin A8 family member I, pseudogene 1 3
MIRT512570 CTDSPL CTD small phosphatase like 2 2
MIRT512708 ZNF134 zinc finger protein 134 2 6
MIRT513177 MOAP1 modulator of apoptosis 1 2 6
MIRT513783 PAWR pro-apoptotic WT1 regulator 2 6
MIRT515099 IRGQ immunity related GTPase Q 2 2
MIRT515481 INCENP inner centromere protein 2 4
MIRT517416 BMP8A bone morphogenetic protein 8a 2 2
MIRT518754 C1orf35 chromosome 1 open reading frame 35 2 2
MIRT519780 ZNF354B zinc finger protein 354B 2 4
MIRT519865 ZFP62 ZFP62 zinc finger protein 2 6
MIRT520510 TRAM2 translocation associated membrane protein 2 2 6
MIRT521068 SLC25A32 solute carrier family 25 member 32 2 6
MIRT526912 ZNF772 zinc finger protein 772 2 6
MIRT527134 GULP1 GULP, engulfment adaptor PTB domain containing 1 2 2
MIRT527867 SLC39A14 solute carrier family 39 member 14 2 2
MIRT528404 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 2 2
MIRT532956 ZNF24 zinc finger protein 24 2 4
MIRT533021 ZFC3H1 zinc finger C3H1-type containing 2 4
MIRT533191 WASL Wiskott-Aldrich syndrome like 2 6
MIRT534191 SLC7A11 solute carrier family 7 member 11 2 2
MIRT534961 PTAR1 protein prenyltransferase alpha subunit repeat containing 1 2 4
MIRT536396 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT537046 GRAMD4 GRAM domain containing 4 2 2
MIRT537125 GOLGA3 golgin A3 2 4
MIRT537183 GFPT2 glutamine-fructose-6-phosphate transaminase 2 2 4
MIRT537652 ERGIC2 ERGIC and golgi 2 2 4
MIRT538632 CCSER2 coiled-coil serine rich protein 2 2 4
MIRT539231 ANP32E acidic nuclear phosphoprotein 32 family member E 2 6
MIRT540099 NPY4R neuropeptide Y receptor Y4 2 2
MIRT540998 ZNF460 zinc finger protein 460 2 4
MIRT541468 AURKA aurora kinase A 2 2
MIRT542680 SESN3 sestrin 3 2 2
MIRT542757 PRRG4 proline rich and Gla domain 4 2 2
MIRT542863 NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 2 2
MIRT542925 HOXC8 homeobox C8 2 2
MIRT543747 SZRD1 SUZ RNA binding domain containing 1 2 2
MIRT544404 ZSCAN12 zinc finger and SCAN domain containing 12 2 2
MIRT544583 AP5Z1 adaptor related protein complex 5 zeta 1 subunit 2 4
MIRT544662 MED19 mediator complex subunit 19 2 2
MIRT545251 GTF2E1 general transcription factor IIE subunit 1 2 2
MIRT545261 TRIM36 tripartite motif containing 36 2 4
MIRT545744 UHRF1BP1 UHRF1 binding protein 1 2 2
MIRT545999 WDR81 WD repeat domain 81 2 2
MIRT546038 VPS4B vacuolar protein sorting 4 homolog B 2 2
MIRT547170 PDZD8 PDZ domain containing 8 2 2
MIRT547273 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT547729 KIF5B kinesin family member 5B 2 2
MIRT548127 GATA6 GATA binding protein 6 2 2
MIRT548203 FNIP1 folliculin interacting protein 1 2 2
MIRT548756 CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2 2
MIRT549641 ZNF75A zinc finger protein 75a 2 2
MIRT549684 ZNF598 zinc finger protein 598 2 2
MIRT550197 MRO maestro 2 2
MIRT550340 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT550536 MYZAP myocardial zonula adherens protein 2 2
MIRT550975 TOR4A torsin family 4 member A 2 2
MIRT551221 CIDEC cell death inducing DFFA like effector c 2 2
MIRT551355 AGBL5 ATP/GTP binding protein like 5 2 2
MIRT551571 LETM1 leucine zipper and EF-hand containing transmembrane protein 1 2 2
MIRT552277 RAB3D RAB3D, member RAS oncogene family 2 2
MIRT552661 ZADH2 zinc binding alcohol dehydrogenase domain containing 2 2 2
MIRT553081 UCK2 uridine-cytidine kinase 2 2 2
MIRT553753 TBC1D8 TBC1 domain family member 8 2 2
MIRT554030 SPCS3 signal peptidase complex subunit 3 2 2
MIRT554099 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT554155 SLX4 SLX4 structure-specific endonuclease subunit 2 2
MIRT554815 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT555522 PMEPA1 prostate transmembrane protein, androgen induced 1 2 2
MIRT555597 PIP5K1C phosphatidylinositol-4-phosphate 5-kinase type 1 gamma 2 2
MIRT555632 PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2 4
MIRT555679 PGAM4 phosphoglycerate mutase family member 4 2 4
MIRT555827 PAX9 paired box 9 2 2
MIRT555868 PAIP1 poly(A) binding protein interacting protein 1 2 2
MIRT555939 NUP43 nucleoporin 43 2 2
MIRT555994 NFYB nuclear transcription factor Y subunit beta 2 2
MIRT556340 MAP2K4 mitogen-activated protein kinase kinase 4 2 2
MIRT556432 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT556585 LHFPL2 LHFPL tetraspan subfamily member 2 2 4
MIRT556801 KIAA1958 KIAA1958 2 2
MIRT558047 EXOC5 exocyst complex component 5 2 2
MIRT558697 CLTA clathrin light chain A 2 2
MIRT559191 BMPR1A bone morphogenetic protein receptor type 1A 2 4
MIRT559639 AKAP10 A-kinase anchoring protein 10 2 2
MIRT559707 AEN apoptosis enhancing nuclease 2 2
MIRT560673 SRFBP1 serum response factor binding protein 1 2 2
MIRT560990 GPBP1L1 GC-rich promoter binding protein 1 like 1 2 2
MIRT562170 HOXA13 homeobox A13 2 2
MIRT562275 GNAQ G protein subunit alpha q 2 2
MIRT563624 ZNF277 zinc finger protein 277 2 2
MIRT563815 FMN1 formin 1 2 2
MIRT564096 TLR3 toll like receptor 3 2 2
MIRT565320 TMEM41A transmembrane protein 41A 2 2
MIRT565986 RNF44 ring finger protein 44 2 2
MIRT566047 REV3L REV3 like, DNA directed polymerase zeta catalytic subunit 2 2
MIRT568236 C11orf24 chromosome 11 open reading frame 24 2 2
MIRT568310 BAK1 BCL2 antagonist/killer 1 2 2
MIRT572376 ATOX1 antioxidant 1 copper chaperone 2 2
MIRT574822 CPEB3 cytoplasmic polyadenylation element binding protein 3 2 2
MIRT609212 PELP1 proline, glutamate and leucine rich protein 1 2 2
MIRT616217 RBM27 RNA binding motif protein 27 2 2
MIRT629087 FASLG Fas ligand 2 2
MIRT632124 FKBP9 FK506 binding protein 9 2 2
MIRT632576 POLQ DNA polymerase theta 2 2
MIRT634799 ENTHD1 ENTH domain containing 1 2 2
MIRT636553 ESRP1 epithelial splicing regulatory protein 1 2 2
MIRT640977 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT653875 SH2B3 SH2B adaptor protein 3 2 2
MIRT655598 OTUD7B OTU deubiquitinase 7B 2 2
MIRT659764 CCDC171 coiled-coil domain containing 171 2 2
MIRT660744 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT681037 AAED1 AhpC/TSA antioxidant enzyme domain containing 1 2 2
MIRT682305 RBM28 RNA binding motif protein 28 2 2
MIRT682573 EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2 2
MIRT686217 ZNF267 zinc finger protein 267 2 2
MIRT687209 PLXNA3 plexin A3 2 2
MIRT690630 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT692419 AGMAT agmatinase 2 2
MIRT694437 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 2
MIRT700725 PNO1 partner of NOB1 homolog 2 2
MIRT701549 NARF nuclear prelamin A recognition factor 2 2
MIRT704379 DAND5 DAN domain BMP antagonist family member 5 2 2
MIRT707935 PPP1R3D protein phosphatase 1 regulatory subunit 3D 2 2
MIRT709939 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT711371 MED7 mediator complex subunit 7 2 2
MIRT712327 PER2 period circadian clock 2 2 2
MIRT714515 SHE Src homology 2 domain containing E 2 2
MIRT715520 G2E3 G2/M-phase specific E3 ubiquitin protein ligase 2 2
MIRT724294 OSMR oncostatin M receptor 2 2
MIRT725358 MUC21 mucin 21, cell surface associated 2 2
MIRT732242 KLF4 Kruppel like factor 4 3 1
MIRT735384 SPAG5 sperm associated antigen 5 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-367 Medpor NULL NULL Microarray osteoblast-like cells line (MG-63) 18408260 2008 up-regulated
miR-367 Activin A NULL 229455 Quantitative real-time PCR Human embryonic stem (hES) cells 19885849 2010 up-regulated
miR-367 Mistletoe lectin-I NULL NULL Microarray colorectal cancer cells CLY cells 20955366 2011 down-regulated
miR-367 Doxorubicin approved 31703 Quantitative real-time PCR heart 22859947 2012 up-regulated
miR-367 Paclitaxel approved 36314 Microarray Ovarian cancer cell lines 24220856 2014 up-regulated
miR-367 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-367 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-miR-367-3p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Siop Treatment Protocol sensitive High Nephroblastoma tissue
hsa-miR-367-3p Paclitaxel 36314 NSC125973 approved resistant High Pan-Cancer cell line (NCI-H460, NCI-H522, NCI-H322M, HOP62, A549, EKVX, MALME-3M, NCI-H226, HT-29, HCT-116, SE-620, HCT-15, HCC2998, COLO205, HS-578T, NCI/ADR-RES, OVCAR8, OVCAR4, ACHN, SN-12C, 786-O, CAKI-1, UO-31, TK-10, A498, SK-MEL-28, UACC-257, M14, UACC-62, SK
hsa-miR-367-3p Doxorubicin 31703 NSC123127 approved sensitive High Hepatocellular Carcinoma tissue and cell line (HepG2)
hsa-miR-367-3p Mitoxantrone 4212 NSC279836 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Sorafenib 216239 NSC747971 approved sensitive Low Hepatocellular Carcinoma cell line (SKhep1, HA22T)
hsa-miR-367-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-367-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM16)
hsa-miR-367-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM36)
hsa-miR-367-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-miR-367-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (SKOV3)
hsa-miR-367-3p Cisplatin 5460033 NSC119875 approved resistant cell line (IGROV-1)
hsa-miR-367-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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