miRTarBase - #MIRT070871


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pre-miRNA Information
pre-miRNA hsa-mir-4282   
Genomic Coordinates chr6: 72967687 - 72967753
Description Homo sapiens miR-4282 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4282
Sequence 40| UAAAAUUUGCAUCCAGGA |57
Evidence Experimental
Experiments SOLiD
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN32074657 13 COSMIC
COSN6331413 18 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1195771339 5 dbSNP
rs755058572 6 dbSNP
rs1245753664 11 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol EIF2S1   
Synonyms EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A
Description eukaryotic translation initiation factor 2 subunit alpha
Transcript NM_004094   
Expression
Putative miRNA Targets on EIF2S1
3'UTR of EIF2S1
(miRNA target sites are highlighted)		 
>EIF2S1|NM_004094|3'UTR
   1 CTTTGTGGGAAACAGAGTCCAATTTAAGGAACACAGAGCAGCGCTTCCTGGCTGTAAATCCTAGACTTGAAAGTTTTCCA
  81 GTATTGAAAACTTCAAAGCTGAATATTTTTTATTTCTAAGTATTTAAATGTTCTAACAGATCAGAACATGAAATGCCCTC
 161 CTAAATGTCAGCTGTTGTCACACAGTAGCTCCAACACTTTGAGCATTTTTAAGGGAGTGGCCTCATTTCACTAGAGACAA
 241 ATCTTTAAGAATAGTTCTAAAATTGGGCTTGTGATTTCCATTTCTGATGTCTCCAGATTGGCACCCCTTTCTAGTTCAAT
 321 GCCTCACGAGATTTGCCAGGGGCATCCAAGGCAAACAATCCCAATCTTTCTATATAAAATGTATTCAAGCAAACATCAAA
 401 TAAATTTCTGGGATATTTAACTATAGGCTTCTTCCTTCTTGTCACCAGTTAAAAGCATTTTAATACTAAGACCCTAATTC
 481 TTTTATCTTTATTTTAGTCTTGATGTGGAACTGTAGGAGCAGGTGAATAAAGGATCTCTATAACAGATCCTTTCAAAAGA
 561 AGAGTTTTAGAGAAAATAAATTTAACTTTAACCACAGTGAAAGTTGACCCTTAGCGGGACAAAGCCTTAAAATGCATTGA
 641 AAGAATTAGATCGGTTCTGTGCCTTTTATCTATTTGAGATTGATGACAACCTGTGTGAGAGAATTTATCACACCACGTCC
 721 TTATTGGAATAATAAGCTACTTGCCTTGAGTTTATAATTCAGGGTGGTAAAGTATGTTTTTAAATTTTAAAAAGCAGCTG
 801 CATTTTTTATTTAGTTGGAATATCACCCAATTTTTTATTTTTATTGCTATTAAAATATCCACTAGATGCCACCTAGAGCT
 881 CCAGTTCTTTATAACAAAACAGGGATCTGTTTGAACACTTACTGTTGTTTTTTTTTTTTTACATGTTTCCATCATTTCTG
 961 TCTTTAAGAACTAATTCGTACATAATAAGTTTCATAGGTAACACATTATTTGAAGTTACAGCTACAGTAGTCAGGTGTAG
1041 AAAATCTTGAGTTGCTTTGGTCTGCTTGTCTTCATAAATTTATTCTCTTATGATACTTGAGGTACCAGTTGTATTTAATT
1121 TTATTCATTATCCCTAGATAGCTATTAAGATACTTAGATTAGACCTAACCCACCATAGTCAATCCAAGACTAGACTACTC
1201 AATATTAAAGGGTCTGGAAAATAGAAGAGTGTGTTGGGCAGGTAGTTTGTACCATTTATGAAGGTTTGTTCCTTTGTTAA
1281 ATTTAGCAGCCTGTACTAGCTTTTGAAATCCAGAAGTTTTAACTTCCAGTGGCTGGTTTCTGAGAGAGTGCCATGATTGC
1361 TAGCCAGCATTCCATATTGGGAATATGTAGAGGAGAACCTGGATGTACTTAAGAGTGGCATATAATTTTCACTTCTGTCT
1441 GTTGAGGCATCAAAAAAACAAGTTTAGAAAGCTGGCAACATGAAGAATGCATTCAAAATATAACAGGTGCTTCTTTGTTG
1521 TACGCAGAGGAATTTTTTCTTTTGATTTTGTTTACTGAAATTTGTTATACTTCAAAAGCCATAACTTGAAAAATACTGGT
1601 GGCGTCGATGGTGAGTGATTTTTATCCCACGTGGGCCTTTTGCTCAGTTCCATGGCAATTTTGTAAATTGACCCTAGCCA
1681 GAGAATAGATCAGTATTTCACTGATACCACGAGGAAAAGAACAAACAAAACTTAAAAGTATTCATACACCTTGCTAACCT
1761 AAAAGACAGCAGGGACAAGATACATATGAGGACAAGGTATACACCCAGTTCTGAATAACTTGAAGAACAGGCTTGGCAAA
1841 GAAGTAAGTTTATCCAAATCTTGAATTTCTGCCAGGCATGGTAGCTCATGCCTGTAACCCTGGCACTTAAGGGGCCAAGG
1921 CAGGAGGATCACTTGAGGCCAGTGAGCTGTGATCACTCCAGTGCACTCGAGCCTGGGTGACAGGGCAAGACCCTGTCTCA
2001 AAAAAAAAAAAAAAAACCAAAAATCTTGAATCTCCCATCAAAGCCTTTTCATTAAAAATACAATTTCATCTACTCCCTAC
2081 TGTACCTTTCACTGATGTCAAGTGGCTATCAATTCATATAGCTGAAAATTAGTGATAGTTTGGGTCTCATTTATGCATAA
2161 ATTAATTGAAAATCAGTAATGGCCAGGAAGAAATATGAATATTCAAACCACTTTTTTCTTTTTTTTTTTTTTTTTTTGGC
2241 AAATGGTGTTATATTGCCTGGGCAGGTCTCGAAATCCTGGGCTCAAGCTATCCTCCTGCCTCTGCCTCTGTAAGAGTGTG
2321 AGCCACCATGCCCCACCCAAACCATTTTTCATATCAGTTATAGCAAAACAAGACAAACCAGTTCTTAATAATGTTCAAAG
2401 TTGGACCCATAGAGACATGCTAAGCACTACATCATGCTAAGAAGAACAGTTATTACTCAGCTGCCATACTTCAGCCATTC
2481 TACTTTTACACCAAGAACAAAATGGCTAGAGATTTTTTTAAAAATACAAATGCCAGTACCTTGCCGAGACTTGTTCACTG
2561 ATTTGCCCCAACCCCAAGGTAATGGTCATCTACTTTGCAACCTATGGAGATCCTGATAGCTCCCATACAAAGTGAGGTAC
2641 ACTGTTGCCAATTTGGAGGCAGGAAGCCATCAAACTAAACGTAGTTTAATTCAGATGAACACCTATCGATATTCAAAAGG
2721 CAAAACAAAAAAACTAATTCCAGGGACATTAGACCTTGGTGAAATGCCAAATGGAAAATGGTGCTTTAAAAGGTAGTCTC
2801 TTACCATATAAGGAATAAGTAAAACATTAGCTTGTGATTTCTCATTATTCAGGTCAATGTTTTAGACACGACTAACAAGG
2881 GACAGTTCAAACTATTAAAGAGAACAAATTTTTACTTAAGCACTTTGAGGTATCCACTCCCCTTAAATGTAAGTTATGTA
2961 TTTTATCTGTTGATTAAGGGGAGGTCCAAGCATTTGTACTTGGCAGGAATGCTGGCAATAGCTTGTGCCAGATTACTGTA
3041 TAAACTTGAAAGTAATAAAAATGTTCTTTAAAAGTA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agGACCU--ACGUUUAAAAu 5'
            || ||  || ||:|||| 
Target 5' tcCTAGACTTGAAAGTTTTc 3'
 59 - 78 138.00 -5.40
2 
miRNA  3' aggaccuacguUUAAAAu 5'
                     |||||| 
Target 5' agttccatggcAATTTTg 3'
 1646 - 1663 120.00 -5.10
3 
miRNA  3' agGACCUA--CGUUUAAAau 5'
            ||| :|  | :|||||  
Target 5' acCTGTGTGAGAGAATTTat 3'
 689 - 708 114.00 -9.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN2375212 2 COSMIC
COSN30479777 8 COSMIC
COSN30138166 44 COSMIC
COSN31500262 50 COSMIC
COSN31600597 108 COSMIC
COSN31533177 344 COSMIC
COSN31583060 481 COSMIC
COSN19451579 772 COSMIC
COSN16668098 802 COSMIC
COSN1170310 941 COSMIC
COSN18965286 1022 COSMIC
COSN22173625 2149 COSMIC
COSN8848346 2173 COSMIC
COSN17463777 2219 COSMIC
COSN23283560 2220 COSMIC
COSN24909433 2662 COSMIC
COSN24906049 2673 COSMIC
COSN26568594 2681 COSMIC
COSN26633399 2693 COSMIC
COSN23760035 2762 COSMIC
COSN28198354 2984 COSMIC
COSN8156283 3064 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs145768394 2 dbSNP
rs761065120 4 dbSNP
rs889284335 10 dbSNP
rs886186422 12 dbSNP
rs370525056 14 dbSNP
rs776938540 16 dbSNP
rs1486798332 18 dbSNP
rs1201275100 22 dbSNP
rs761968082 23 dbSNP
rs200889859 24 dbSNP
rs773276647 25 dbSNP
rs766276886 27 dbSNP
rs183335075 30 dbSNP
rs867282782 33 dbSNP
rs1454210150 34 dbSNP
rs1222691811 35 dbSNP
rs533452032 37 dbSNP
rs762585301 39 dbSNP
rs964372173 40 dbSNP
rs766318218 43 dbSNP
rs1377622166 44 dbSNP
rs1466840185 46 dbSNP
rs751413049 51 dbSNP
rs759254508 55 dbSNP
rs754823677 60 dbSNP
rs767158582 63 dbSNP
rs975615115 64 dbSNP
rs1233430919 65 dbSNP
rs771408253 67 dbSNP
rs148521707 69 dbSNP
rs1233628026 70 dbSNP
rs1467629867 74 dbSNP
rs755821688 79 dbSNP
rs1449483118 81 dbSNP
rs1479778002 82 dbSNP
rs1376157986 84 dbSNP
rs1197690344 88 dbSNP
rs777480129 92 dbSNP
rs748782421 95 dbSNP
rs186206810 96 dbSNP
rs780646163 101 dbSNP
rs1434136098 106 dbSNP
rs550657936 111 dbSNP
rs774882746 117 dbSNP
rs1460128991 118 dbSNP
rs1332835155 121 dbSNP
rs1400428127 125 dbSNP
rs760071104 126 dbSNP
rs769082094 129 dbSNP
rs1483916542 134 dbSNP
rs1253909246 135 dbSNP
rs767809095 138 dbSNP
rs914111750 145 dbSNP
rs866285120 149 dbSNP
rs983880757 154 dbSNP
rs1294568989 158 dbSNP
rs1306033130 160 dbSNP
rs553539967 166 dbSNP
rs1290041663 167 dbSNP
rs1233722439 178 dbSNP
rs572258832 181 dbSNP
rs979540808 183 dbSNP
rs1313284380 188 dbSNP
rs1336324509 198 dbSNP
rs370639459 203 dbSNP
rs752289680 206 dbSNP
rs925255443 207 dbSNP
rs969243033 218 dbSNP
rs116606923 221 dbSNP
rs927924819 223 dbSNP
rs1157459331 227 dbSNP
rs1361921889 230 dbSNP
rs1472454497 254 dbSNP
rs1220298247 259 dbSNP
rs1190168179 264 dbSNP
rs536467432 275 dbSNP
rs1253390461 281 dbSNP
rs1202470741 289 dbSNP
rs917830823 294 dbSNP
rs1465119865 303 dbSNP
rs117099951 320 dbSNP
rs1321894098 325 dbSNP
rs1048014168 328 dbSNP
rs1203363174 335 dbSNP
rs1349634198 345 dbSNP
rs1262136355 354 dbSNP
rs1246829905 357 dbSNP
rs1052332943 359 dbSNP
rs202015776 360 dbSNP
rs1435868461 362 dbSNP
rs778311432 365 dbSNP
rs946679919 370 dbSNP
rs1194743067 373 dbSNP
rs1400520556 375 dbSNP
rs1043830234 391 dbSNP
rs1165522689 395 dbSNP
rs1474766296 398 dbSNP
rs889192553 400 dbSNP
rs1368395020 401 dbSNP
rs943568906 404 dbSNP
rs1449492592 411 dbSNP
rs1249540070 413 dbSNP
rs1186210270 414 dbSNP
rs1191729621 424 dbSNP
rs1431256849 426 dbSNP
rs1267873062 427 dbSNP
rs142818296 429 dbSNP
rs1175423111 430 dbSNP
rs1037434481 433 dbSNP
rs1290921871 445 dbSNP
rs1229255011 462 dbSNP
rs1389752039 468 dbSNP
rs11547441 475 dbSNP
rs1295681523 482 dbSNP
rs533867013 485 dbSNP
rs1331884810 489 dbSNP
rs1344712809 503 dbSNP
rs995807589 523 dbSNP
rs1028533319 528 dbSNP
rs1365560077 539 dbSNP
rs1169740809 541 dbSNP
rs1285759003 547 dbSNP
rs1429832871 550 dbSNP
rs145778255 561 dbSNP
rs955808634 563 dbSNP
rs1246898275 564 dbSNP
rs1289341152 572 dbSNP
rs1351006085 581 dbSNP
rs1008511729 584 dbSNP
rs1281644078 586 dbSNP
rs1005212160 610 dbSNP
rs1484083231 613 dbSNP
rs140900406 616 dbSNP
rs1189650745 617 dbSNP
rs1221583278 622 dbSNP
rs1271033891 627 dbSNP
rs969106552 637 dbSNP
rs377613942 638 dbSNP
rs1412412824 639 dbSNP
rs1035278237 640 dbSNP
rs190620053 645 dbSNP
rs146105703 653 dbSNP
rs563005199 654 dbSNP
rs12590079 658 dbSNP
rs1408845684 660 dbSNP
rs1425463581 670 dbSNP
rs979389805 671 dbSNP
rs543823646 679 dbSNP
rs925370391 685 dbSNP
rs1305021782 694 dbSNP
rs866648039 702 dbSNP
rs1473569791 703 dbSNP
rs1231071233 706 dbSNP
rs1203976694 712 dbSNP
rs1443025511 714 dbSNP
rs757460463 717 dbSNP
rs943475534 718 dbSNP
rs1337932739 724 dbSNP
rs1170187373 728 dbSNP
rs1040433018 730 dbSNP
rs1237246726 732 dbSNP
rs1349238218 733 dbSNP
rs1279442914 735 dbSNP
rs574811108 739 dbSNP
rs929453977 740 dbSNP
rs1335792406 741 dbSNP
rs1349485399 749 dbSNP
rs1467958708 751 dbSNP
rs1404893404 755 dbSNP
rs542292259 757 dbSNP
rs1246157016 773 dbSNP
rs917959307 773 dbSNP
rs1159679909 774 dbSNP
rs560694669 776 dbSNP
rs949315442 780 dbSNP
rs1047666483 788 dbSNP
rs1176484478 803 dbSNP
rs17104281 810 dbSNP
rs1005244700 830 dbSNP
rs1016626048 831 dbSNP
rs904829094 831 dbSNP
rs907692131 831 dbSNP
rs17104283 838 dbSNP
rs1268985583 849 dbSNP
rs1211000243 850 dbSNP
rs1327478570 855 dbSNP
rs1284182842 856 dbSNP
rs1229331432 859 dbSNP
rs1381950546 865 dbSNP
rs1221690352 868 dbSNP
rs527884008 870 dbSNP
rs1381650839 882 dbSNP
rs552942330 885 dbSNP
rs1343157631 890 dbSNP
rs1439347872 890 dbSNP
rs1158087735 901 dbSNP
rs375612303 903 dbSNP
rs1405952263 923 dbSNP
rs562191610 923 dbSNP
rs1161809610 925 dbSNP
rs1034734951 926 dbSNP
rs960862363 927 dbSNP
rs1243167864 928 dbSNP
rs1290189869 928 dbSNP
rs1358056380 928 dbSNP
rs1432145483 928 dbSNP
rs34318358 928 dbSNP
rs900261869 928 dbSNP
rs987984728 929 dbSNP
rs995977928 931 dbSNP
rs1359425561 934 dbSNP
rs1288113995 941 dbSNP
rs397766076 941 dbSNP
rs1383484837 942 dbSNP
rs1424052977 943 dbSNP
rs1351572498 944 dbSNP
rs1169783707 946 dbSNP
rs1399185716 950 dbSNP
rs1161557478 951 dbSNP
rs1424109131 954 dbSNP
rs1390795835 957 dbSNP
rs1170546578 961 dbSNP
rs1427026827 966 dbSNP
rs1390082450 978 dbSNP
rs1051856466 979 dbSNP
rs979295059 982 dbSNP
rs1328593221 983 dbSNP
rs1267417221 986 dbSNP
rs183671945 995 dbSNP
rs1334848283 1005 dbSNP
rs532134486 1006 dbSNP
rs781644450 1020 dbSNP
rs1305459043 1023 dbSNP
rs1294350352 1025 dbSNP
rs147836861 1026 dbSNP
rs966838457 1027 dbSNP
rs1369382926 1040 dbSNP
rs1001040761 1042 dbSNP
rs1244518214 1052 dbSNP
rs923379440 1059 dbSNP
rs1371079475 1060 dbSNP
rs929492174 1065 dbSNP
rs1032552429 1085 dbSNP
rs1354186466 1088 dbSNP
rs1177007553 1090 dbSNP
rs74058416 1092 dbSNP
rs1193928961 1095 dbSNP
rs1199144424 1103 dbSNP
rs942271664 1112 dbSNP
rs990949751 1114 dbSNP
rs141325817 1116 dbSNP
rs970774531 1117 dbSNP
rs1250422012 1120 dbSNP
rs1185690320 1127 dbSNP
rs983747172 1129 dbSNP
rs1210316636 1133 dbSNP
rs1281213988 1138 dbSNP
rs1325222252 1138 dbSNP
rs1222637504 1140 dbSNP
rs1351080302 1141 dbSNP
rs770107358 1143 dbSNP
rs547862762 1145 dbSNP
rs1389776895 1151 dbSNP
rs904862877 1154 dbSNP
rs1303657928 1160 dbSNP
rs1467833982 1168 dbSNP
rs1001873098 1173 dbSNP
rs1189278127 1175 dbSNP
rs1375352067 1176 dbSNP
rs75744302 1183 dbSNP
rs1460887985 1186 dbSNP
rs1414881704 1187 dbSNP
rs75955766 1193 dbSNP
rs896224299 1199 dbSNP
rs146973725 1200 dbSNP
rs868435072 1201 dbSNP
rs1020762629 1210 dbSNP
rs967827292 1213 dbSNP
rs1202819733 1218 dbSNP
rs1329552351 1223 dbSNP
rs921799538 1228 dbSNP
rs1338305019 1229 dbSNP
rs1380047150 1230 dbSNP
rs749449805 1233 dbSNP
rs559859294 1234 dbSNP
rs1295670273 1239 dbSNP
rs558439482 1241 dbSNP
rs1328177944 1253 dbSNP
rs965113840 1256 dbSNP
rs945743960 1257 dbSNP
rs1042628801 1267 dbSNP
rs902766340 1269 dbSNP
rs370644660 1277 dbSNP
rs976103209 1285 dbSNP
rs1445866895 1290 dbSNP
rs1240920517 1297 dbSNP
rs1182526730 1323 dbSNP
rs923030352 1338 dbSNP
rs1263656893 1342 dbSNP
rs1465193435 1342 dbSNP
rs373197062 1345 dbSNP
rs1349932260 1353 dbSNP
rs1265909864 1354 dbSNP
rs1248305417 1359 dbSNP
rs1032498643 1365 dbSNP
rs1261560996 1366 dbSNP
rs923372368 1376 dbSNP
rs780287322 1378 dbSNP
rs1328417147 1379 dbSNP
rs1316737057 1381 dbSNP
rs1381991169 1382 dbSNP
rs1461032854 1391 dbSNP
rs895341382 1399 dbSNP
rs1012724593 1406 dbSNP
rs1025072792 1423 dbSNP
rs149476732 1438 dbSNP
rs1305451041 1445 dbSNP
rs1426764552 1448 dbSNP
rs983476109 1453 dbSNP
rs1193141260 1462 dbSNP
rs1014915969 1466 dbSNP
rs1162363499 1475 dbSNP
rs983910882 1488 dbSNP
rs963255658 1497 dbSNP
rs909386086 1501 dbSNP
rs1267975580 1505 dbSNP
rs538260528 1513 dbSNP
rs1489834638 1521 dbSNP
rs942136592 1524 dbSNP
rs556315606 1525 dbSNP
rs1044706661 1533 dbSNP
rs1268592406 1540 dbSNP
rs1227197516 1542 dbSNP
rs574753366 1543 dbSNP
rs746886034 1546 dbSNP
rs921747976 1549 dbSNP
rs931852146 1556 dbSNP
rs1331976382 1561 dbSNP
rs927521034 1564 dbSNP
rs937704369 1565 dbSNP
rs1302040702 1569 dbSNP
rs760722027 1572 dbSNP
rs201705161 1574 dbSNP
rs1398222216 1580 dbSNP
rs1165725835 1582 dbSNP
rs1474966528 1582 dbSNP
rs1386536636 1594 dbSNP
rs45479091 1598 dbSNP
rs560559251 1604 dbSNP
rs572684606 1605 dbSNP
rs17104285 1607 dbSNP
rs776537294 1608 dbSNP
rs903701121 1619 dbSNP
rs1195388024 1620 dbSNP
rs1041396833 1632 dbSNP
rs759220429 1642 dbSNP
rs188146687 1648 dbSNP
rs1484938950 1653 dbSNP
rs1345459627 1656 dbSNP
rs564789435 1659 dbSNP
rs1270309793 1673 dbSNP
rs1336954760 1675 dbSNP
rs1326261308 1678 dbSNP
rs936889700 1682 dbSNP
rs1490982862 1687 dbSNP
rs1409074136 1692 dbSNP
rs143036337 1702 dbSNP
rs866685309 1709 dbSNP
rs895277448 1711 dbSNP
rs1012426533 1712 dbSNP
rs1420006581 1715 dbSNP
rs1025442615 1717 dbSNP
rs550435405 1727 dbSNP
rs1296580619 1732 dbSNP
rs562373550 1739 dbSNP
rs148189748 1753 dbSNP
rs547924535 1766 dbSNP
rs1159384264 1772 dbSNP
rs950740869 1775 dbSNP
rs112928191 1784 dbSNP
rs1014863632 1785 dbSNP
rs3248 1787 dbSNP
rs1323190695 1788 dbSNP
rs1366154012 1792 dbSNP
rs1406670242 1795 dbSNP
rs980253052 1796 dbSNP
rs1339858527 1798 dbSNP
rs765005789 1806 dbSNP
rs1344673390 1808 dbSNP
rs752279131 1810 dbSNP
rs1383107041 1819 dbSNP
rs753105729 1822 dbSNP
rs1450192881 1823 dbSNP
rs1405013121 1829 dbSNP
rs762534879 1831 dbSNP
rs1402445737 1835 dbSNP
rs1315336419 1842 dbSNP
rs993459822 1849 dbSNP
rs917599335 1852 dbSNP
rs1028922761 1853 dbSNP
rs1445271788 1861 dbSNP
rs1245203589 1864 dbSNP
rs1238507158 1866 dbSNP
rs1292551926 1872 dbSNP
rs1362282968 1875 dbSNP
rs763601129 1878 dbSNP
rs1220940988 1886 dbSNP
rs987323922 1890 dbSNP
rs1481171965 1896 dbSNP
rs1284128250 1899 dbSNP
rs944999871 1900 dbSNP
rs1179307062 1901 dbSNP
rs1359455610 1907 dbSNP
rs1316737147 1918 dbSNP
rs1042161490 1921 dbSNP
rs527486577 1922 dbSNP
rs1381581684 1931 dbSNP
rs1289272548 1960 dbSNP
rs1416902457 1969 dbSNP
rs1317470602 1970 dbSNP
rs191425312 1972 dbSNP
rs1387221408 1973 dbSNP
rs1161737934 1978 dbSNP
rs1444277101 1982 dbSNP
rs182847745 1983 dbSNP
rs1425964540 1992 dbSNP
rs1038859739 1993 dbSNP
rs1223804981 1999 dbSNP
rs764539546 1999 dbSNP
rs781249037 1999 dbSNP
rs1269363531 2000 dbSNP
rs1295796430 2000 dbSNP
rs1491162464 2000 dbSNP
rs60823341 2000 dbSNP
rs796319759 2000 dbSNP
rs796596107 2000 dbSNP
rs869218370 2000 dbSNP
rs977691201 2000 dbSNP
rs1405551104 2001 dbSNP
rs79830340 2002 dbSNP
rs1161601399 2003 dbSNP
rs1349173464 2006 dbSNP
rs537777392 2009 dbSNP
rs1355373777 2010 dbSNP
rs58395304 2012 dbSNP
rs1427125407 2013 dbSNP
rs977193343 2014 dbSNP
rs1980817 2015 dbSNP
rs1315941020 2016 dbSNP
rs935668169 2016 dbSNP
rs1361682920 2017 dbSNP
rs1243790712 2018 dbSNP
rs1030622584 2020 dbSNP
rs1054010155 2024 dbSNP
rs1305397668 2027 dbSNP
rs916843341 2028 dbSNP
rs1308595350 2030 dbSNP
rs886480158 2031 dbSNP
rs1004878197 2032 dbSNP
rs1404419694 2035 dbSNP
rs1207113709 2040 dbSNP
rs1374081909 2042 dbSNP
rs370537627 2045 dbSNP
rs1460721526 2054 dbSNP
rs948345943 2055 dbSNP
rs1046549435 2056 dbSNP
rs1480481952 2061 dbSNP
rs1354129330 2063 dbSNP
rs1177661475 2074 dbSNP
rs1177665167 2078 dbSNP
rs549359355 2080 dbSNP
rs1243301971 2087 dbSNP
rs1427855315 2090 dbSNP
rs1445941386 2093 dbSNP
rs1219474984 2098 dbSNP
rs1199255398 2105 dbSNP
rs72719125 2109 dbSNP
rs980159776 2112 dbSNP
rs1250697167 2129 dbSNP
rs1004903072 2141 dbSNP
rs1413070874 2145 dbSNP
rs1479481144 2157 dbSNP
rs1237133272 2160 dbSNP
rs1036422273 2165 dbSNP
rs899142713 2185 dbSNP
rs1172334742 2188 dbSNP
rs994806059 2197 dbSNP
rs1317444501 2209 dbSNP
rs1055302755 2211 dbSNP
rs1464846432 2211 dbSNP
rs1337591793 2212 dbSNP
rs33969193 2212 dbSNP
rs398099431 2212 dbSNP
rs569738880 2212 dbSNP
rs1337650313 2213 dbSNP
rs1385241991 2214 dbSNP
rs1450620753 2215 dbSNP
rs1454798905 2215 dbSNP
rs1366032660 2217 dbSNP
rs375072844 2218 dbSNP
rs1199638124 2219 dbSNP
rs1241116809 2219 dbSNP
rs1262371738 2219 dbSNP
rs1416745732 2219 dbSNP
rs1462371277 2219 dbSNP
rs74058417 2219 dbSNP
rs780069831 2219 dbSNP
rs913473402 2219 dbSNP
rs111526340 2220 dbSNP
rs945081460 2221 dbSNP
rs1294006847 2222 dbSNP
rs373689711 2223 dbSNP
rs191353963 2224 dbSNP
rs200888833 2225 dbSNP
rs546433706 2226 dbSNP
rs977141089 2227 dbSNP
rs936435707 2228 dbSNP
rs1417338402 2229 dbSNP
rs1359413237 2230 dbSNP
rs1163664465 2233 dbSNP
rs1364921246 2239 dbSNP
rs1455785358 2240 dbSNP
rs1188243448 2241 dbSNP
rs1428852912 2244 dbSNP
rs558104083 2247 dbSNP
rs949567827 2248 dbSNP
rs1477404306 2249 dbSNP
rs1487919177 2250 dbSNP
rs1176874280 2252 dbSNP
rs1038724543 2253 dbSNP
rs1408626190 2254 dbSNP
rs1468410672 2257 dbSNP
rs1328504567 2259 dbSNP
rs1293867329 2270 dbSNP
rs1333695317 2271 dbSNP
rs925702527 2272 dbSNP
rs1303287077 2277 dbSNP
rs185021961 2279 dbSNP
rs187881256 2282 dbSNP
rs1340437161 2287 dbSNP
rs1462319374 2291 dbSNP
rs1224580016 2297 dbSNP
rs1285553052 2301 dbSNP
rs933146511 2306 dbSNP
rs12431860 2307 dbSNP
rs562399430 2308 dbSNP
rs1221330765 2309 dbSNP
rs915597793 2310 dbSNP
rs1489860247 2311 dbSNP
rs1289443662 2312 dbSNP
rs948315311 2314 dbSNP
rs781531595 2327 dbSNP
rs143108366 2328 dbSNP
rs1341734987 2332 dbSNP
rs1250023116 2334 dbSNP
rs771864995 2337 dbSNP
rs529666845 2343 dbSNP
rs1346722022 2344 dbSNP
rs1406252065 2352 dbSNP
rs371506583 2352 dbSNP
rs1328793427 2355 dbSNP
rs1322299415 2361 dbSNP
rs1240349693 2377 dbSNP
rs1016291855 2379 dbSNP
rs940874472 2385 dbSNP
rs1464869614 2386 dbSNP
rs1429906965 2387 dbSNP
rs1178425156 2392 dbSNP
rs1199943784 2397 dbSNP
rs878877304 2406 dbSNP
rs1246273111 2407 dbSNP
rs1182583527 2409 dbSNP
rs1431189758 2411 dbSNP
rs1248634573 2428 dbSNP
rs746910718 2439 dbSNP
rs1036370226 2445 dbSNP
rs1198448109 2446 dbSNP
rs1324634713 2447 dbSNP
rs1172215983 2448 dbSNP
rs192312809 2448 dbSNP
rs1408916752 2454 dbSNP
rs994919654 2455 dbSNP
rs1273781538 2457 dbSNP
rs750844104 2459 dbSNP
rs13595 2466 dbSNP
rs1337191753 2467 dbSNP
rs1328780147 2470 dbSNP
rs1316308043 2472 dbSNP
rs1360493512 2488 dbSNP
rs1445787296 2492 dbSNP
rs1406071818 2494 dbSNP
rs371203643 2513 dbSNP
rs555579229 2513 dbSNP
rs527353355 2520 dbSNP
rs1020565925 2521 dbSNP
rs1424352778 2527 dbSNP
rs1159246864 2528 dbSNP
rs1436126186 2530 dbSNP
rs146150192 2531 dbSNP
rs1350935304 2537 dbSNP
rs978952846 2538 dbSNP
rs1225005011 2542 dbSNP
rs1283236215 2544 dbSNP
rs185318407 2546 dbSNP
rs1245397305 2549 dbSNP
rs1352271028 2550 dbSNP
rs967171786 2559 dbSNP
rs998693718 2561 dbSNP
rs1032886193 2572 dbSNP
rs531522851 2574 dbSNP
rs10131175 2575 dbSNP
rs189808545 2584 dbSNP
rs1489802871 2586 dbSNP
rs535869937 2591 dbSNP
rs1239062310 2594 dbSNP
rs554172718 2599 dbSNP
rs1316963402 2601 dbSNP
rs1383033462 2601 dbSNP
rs761117695 2602 dbSNP
rs1358541084 2603 dbSNP
rs1052015088 2605 dbSNP
rs971486036 2613 dbSNP
rs982354777 2614 dbSNP
rs928226859 2623 dbSNP
rs556543577 2625 dbSNP
rs1379792210 2642 dbSNP
rs972201725 2649 dbSNP
rs1445520723 2650 dbSNP
rs1387258121 2653 dbSNP
rs1180510390 2667 dbSNP
rs1472635538 2674 dbSNP
rs1037590336 2678 dbSNP
rs796459437 2681 dbSNP
rs1425338421 2684 dbSNP
rs1166025652 2685 dbSNP
rs577275809 2686 dbSNP
rs539367892 2694 dbSNP
rs1359744440 2701 dbSNP
rs1316674264 2703 dbSNP
rs1386627556 2703 dbSNP
rs1329922835 2704 dbSNP
rs539969540 2708 dbSNP
rs558231222 2709 dbSNP
rs576603066 2710 dbSNP
rs1040254368 2722 dbSNP
rs1020882930 2723 dbSNP
rs1162869133 2727 dbSNP
rs1245998255 2731 dbSNP
rs903102171 2733 dbSNP
rs368580546 2737 dbSNP
rs1188618613 2738 dbSNP
rs1263043313 2742 dbSNP
rs1293936945 2751 dbSNP
rs1490352675 2756 dbSNP
rs967483293 2760 dbSNP
rs998808285 2765 dbSNP
rs558065788 2773 dbSNP
rs1000405831 2776 dbSNP
rs576236133 2780 dbSNP
rs957733708 2783 dbSNP
rs1316021596 2798 dbSNP
rs1012642039 2801 dbSNP
rs1179970877 2803 dbSNP
rs770939237 2803 dbSNP
rs1347526260 2805 dbSNP
rs1237729036 2816 dbSNP
rs879251180 2820 dbSNP
rs1445331462 2824 dbSNP
rs1173021043 2825 dbSNP
rs1464358957 2827 dbSNP
rs921726382 2829 dbSNP
rs954633345 2835 dbSNP
rs1481698579 2836 dbSNP
rs1383963707 2840 dbSNP
rs1268930928 2848 dbSNP
rs1188919149 2857 dbSNP
rs1457820320 2859 dbSNP
rs987209622 2860 dbSNP
rs555788653 2868 dbSNP
rs776428680 2871 dbSNP
rs981516478 2875 dbSNP
rs1313847863 2877 dbSNP
rs1299341955 2880 dbSNP
rs139507541 2893 dbSNP
rs371197426 2893 dbSNP
rs940468064 2893 dbSNP
rs1328888180 2897 dbSNP
rs1015252913 2912 dbSNP
rs1400099771 2912 dbSNP
rs759432502 2915 dbSNP
rs1471266446 2917 dbSNP
rs543885907 2918 dbSNP
rs1173381242 2919 dbSNP
rs895795152 2920 dbSNP
rs1432023375 2930 dbSNP
rs920739378 2931 dbSNP
rs930821748 2934 dbSNP
rs1316497277 2942 dbSNP
rs1338681808 2955 dbSNP
rs576337210 2956 dbSNP
rs986199623 2962 dbSNP
rs1180186583 2964 dbSNP
rs1456165810 2968 dbSNP
rs1237382596 2970 dbSNP
rs1204032379 2983 dbSNP
rs1244008516 2984 dbSNP
rs1270660458 2986 dbSNP
rs1014760227 2997 dbSNP
rs1209515995 3000 dbSNP
rs769491230 3005 dbSNP
rs910632374 3007 dbSNP
rs1311539803 3018 dbSNP
rs1238332976 3025 dbSNP
rs1376400743 3036 dbSNP
rs1316231997 3037 dbSNP
rs762060877 3041 dbSNP
rs1196467563 3053 dbSNP
rs1400694134 3063 dbSNP
rs114593741 3067 dbSNP
rs541441308 3070 dbSNP
rs1454749972 3074 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 1965.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084066. RNA binding protein: AGO2. Condition:CLIP_noemetine_SantaCruzAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_004094 | 3UTR | UAUUAAAGAGAACAAAUUUUUACUUAAGCACUUUGAGGUAUCCACUCCCCUUAAAUGUAAGUUAUGUAUUUUAUCUGUUGAUUAAGGGGAGGUCCAAGCAUUUGUACUUGGCAGGAAUGCUGGCAAUAGCUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_004094 | 3UTR | UUAAAGAGAACAAAUUUUUACUUAAGCACUUUGAGGUAUCCACUCCCCUUAAAUGUAAGUUAUGUAUUUUAUCUGUUGAUUAAGGGGAGGUCCAAGCAUUUGUACUUGGCAGGAAUGCUGGCAAUAGCUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_004094 | 3UTR | CUAUUAAAGAGAACAAAUUUUUACUUAAGCACUUUGAGGUAUCCACUCCCCUUAAAUGUAAGUUAUGUAUUUUAUCUGUUGAUUAAGGGGAGGUCCAAGCAUUUGUACUUGGCAGGAAUGCUGGCAAUAGCUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_004094 | 3UTR | AAAGAGAACAAAUUUUUACUUAAGCACUUUGAGGUAUCCACUCCCCUUAAAUGUAAGUUAUGUAUUUUAUCUGUUGAUUAAGGGGAGGUCCAAGCAUUUGUACUUGGCAGGAAUGCUGGCAAUAGCUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903837
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_b
Location of target site NM_004094 | 3UTR | CUAUUAAAGAGAACAAAUUUUUACUUAAGCACUUUGAGGUAUCCACUCCCCUUAAAUGUAAGUUAUGUAUUUUAUCUGUUGAUUAAGGGGAGGUCCAAGCAUUUGUACUUGGCAGGAAUGCUGGCAAUAGCUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_004094 | 3UTR | CAAACUAUUAAAGAGAACAAAUUUUUACUUAAGCACUUUGAGGUAUCCACUCCCCUUAAAUGUAAGUUAUGUAUUUUAUCUGUUGAUUAAGGGGAGGUCCAAGCAUUUGUACUUGGCAGGAAUGCUGGCAAUAGCUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM1084066
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_SantaCruzAb
Location of target site ENST00000256383.4 | 3UTR | AGAACAAAUUUUUACUUAAGCACUUUGAGGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 8 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000256383.4 | 3UTR | AACAAAUUUUUACUUAAGCACUUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
280 hsa-miR-4282 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT057628 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT060732 RPS3 ribosomal protein S3 2 2
MIRT063371 ETNK1 ethanolamine kinase 1 2 2
MIRT066257 LRIG3 leucine rich repeats and immunoglobulin like domains 3 2 4
MIRT070774 HIF1A hypoxia inducible factor 1 alpha subunit 2 2
MIRT070871 EIF2S1 eukaryotic translation initiation factor 2 subunit alpha 2 4
MIRT078056 PCTP phosphatidylcholine transfer protein 2 2
MIRT078408 DCAF7 DDB1 and CUL4 associated factor 7 2 4
MIRT084059 PPP1R3D protein phosphatase 1 regulatory subunit 3D 2 2
MIRT093537 GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 2 6
MIRT096072 SFXN1 sideroflexin 1 2 2
MIRT098316 REV3L REV3 like, DNA directed polymerase zeta catalytic subunit 2 2
MIRT100493 UHRF1BP1 UHRF1 binding protein 1 2 2
MIRT102254 HBP1 HMG-box transcription factor 1 2 4
MIRT105318 VPS37A VPS37A, ESCRT-I subunit 2 2
MIRT114143 MZT1 mitotic spindle organizing protein 1 2 4
MIRT114873 DICER1 dicer 1, ribonuclease III 2 2
MIRT134683 PNRC2 proline rich nuclear receptor coactivator 2 2 2
MIRT137640 RCOR1 REST corepressor 1 2 2
MIRT155449 CCNT2 cyclin T2 2 4
MIRT165656 DCTN4 dynactin subunit 4 2 2
MIRT177570 CSTF2T cleavage stimulation factor subunit 2 tau variant 2 4
MIRT188514 E2F7 E2F transcription factor 7 2 10
MIRT193019 TMOD3 tropomodulin 3 2 4
MIRT195823 GADD45A growth arrest and DNA damage inducible alpha 2 2
MIRT195885 DEPDC1 DEP domain containing 1 2 6
MIRT206029 NUP50 nucleoporin 50 2 6
MIRT212148 CLCN3 chloride voltage-gated channel 3 2 2
MIRT213999 DCP2 decapping mRNA 2 2 2
MIRT214650 HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 2 2
MIRT221568 CBX3 chromobox 3 2 2
MIRT224544 ZNF623 zinc finger protein 623 2 2
MIRT227654 SET SET nuclear proto-oncogene 2 2
MIRT229992 CHIC1 cysteine rich hydrophobic domain 1 2 2
MIRT238968 QKI QKI, KH domain containing RNA binding 2 2
MIRT239825 ACTB actin beta 2 2
MIRT241084 ZXDA zinc finger, X-linked, duplicated A 2 4
MIRT244852 ZBTB5 zinc finger and BTB domain containing 5 2 2
MIRT264534 TARDBP TAR DNA binding protein 2 2
MIRT271438 SKI SKI proto-oncogene 2 2
MIRT271597 ENAH ENAH, actin regulator 2 2
MIRT294332 ZNF264 zinc finger protein 264 2 2
MIRT296341 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT301715 TEF TEF, PAR bZIP transcription factor 2 2
MIRT308549 ZNF654 zinc finger protein 654 2 2
MIRT313866 DEPDC1B DEP domain containing 1B 2 2
MIRT315529 MARCKS myristoylated alanine rich protein kinase C substrate 2 2
MIRT321066 RABGEF1 RAB guanine nucleotide exchange factor 1 2 2
MIRT343777 NUTF2 nuclear transport factor 2 2 2
MIRT359109 MAP1B microtubule associated protein 1B 2 2
MIRT397393 GOLGA3 golgin A3 2 4
MIRT400822 CPEB2 cytoplasmic polyadenylation element binding protein 2 2 2
MIRT442171 DSEL dermatan sulfate epimerase-like 2 2
MIRT442777 JAG1 jagged 1 2 2
MIRT442862 SCARF1 scavenger receptor class F member 1 2 4
MIRT442919 PCBD2 pterin-4 alpha-carbinolamine dehydratase 2 2 2
MIRT444567 TRA2B transformer 2 beta homolog 2 2
MIRT444718 CMSS1 cms1 ribosomal small subunit homolog (yeast) 2 2
MIRT445018 RBMS3 RNA binding motif single stranded interacting protein 3 2 2
MIRT445853 LRRC1 leucine rich repeat containing 1 2 2
MIRT446242 HELZ helicase with zinc finger 2 2
MIRT446542 GOLGA8B golgin A8 family member B 2 2
MIRT446643 SPTY2D1 SPT2 chromatin protein domain containing 1 2 2
MIRT446948 ZMAT3 zinc finger matrin-type 3 2 4
MIRT447061 KCNAB1 potassium voltage-gated channel subfamily A member regulatory beta subunit 1 2 2
MIRT447327 ZSCAN21 zinc finger and SCAN domain containing 21 2 2
MIRT447995 CDX1 caudal type homeobox 1 2 2
MIRT448543 RHEBP1 RHEB pseudogene 1 2 6
MIRT448752 HINT1 histidine triad nucleotide binding protein 1 2 2
MIRT448772 GOLGA8A golgin A8 family member A 2 2
MIRT449342 WDR26 WD repeat domain 26 2 2
MIRT450011 SLC16A6 solute carrier family 16 member 6 2 4
MIRT450229 PCNX pecanex homolog 1 2 2
MIRT450340 MRPL17 mitochondrial ribosomal protein L17 2 4
MIRT450381 MSI2 musashi RNA binding protein 2 2 2
MIRT450759 PGGT1B protein geranylgeranyltransferase type I subunit beta 2 2
MIRT450809 NRCAM neuronal cell adhesion molecule 2 2
MIRT450947 ATAD2 ATPase family, AAA domain containing 2 2 2
MIRT459095 CCPG1 cell cycle progression 1 2 2
MIRT462428 TWISTNB TWIST neighbor 2 2
MIRT465200 TROVE2 TROVE domain family member 2 2 4
MIRT467382 SON SON DNA binding protein 2 4
MIRT468546 SERP1 stress associated endoplasmic reticulum protein 1 2 2
MIRT471506 PDE4D phosphodiesterase 4D 2 2
MIRT471981 NR3C1 nuclear receptor subfamily 3 group C member 1 2 2
MIRT474478 KLHL11 kelch like family member 11 2 8
MIRT475011 KANSL1 KAT8 regulatory NSL complex subunit 1 2 8
MIRT480341 C5orf51 chromosome 5 open reading frame 51 2 2
MIRT482696 TEX9 testis expressed 9 2 6
MIRT483462 YTHDF1 YTH N6-methyladenosine RNA binding protein 1 2 6
MIRT485623 FAM217B family with sequence similarity 217 member B 2 2
MIRT485714 CASP16 caspase 16, pseudogene 2 8
MIRT486279 SEC23A Sec23 homolog A, coat complex II component 2 2
MIRT491000 PEBP1 phosphatidylethanolamine binding protein 1 2 4
MIRT492594 PPIL4 peptidylprolyl isomerase like 4 2 2
MIRT493365 KIF5B kinesin family member 5B 2 2
MIRT494316 CDKN1B cyclin dependent kinase inhibitor 1B 2 2
MIRT495208 EDN3 endothelin 3 2 2
MIRT497011 TCF15 transcription factor 15 2 2
MIRT498512 FRK fyn related Src family tyrosine kinase 2 2
MIRT498778 PARP15 poly(ADP-ribose) polymerase family member 15 2 2
MIRT501045 SMG1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 2 6
MIRT502939 CDC37L1 cell division cycle 37 like 1 2 8
MIRT504806 VHL von Hippel-Lindau tumor suppressor 2 6
MIRT505656 SHMT1 serine hydroxymethyltransferase 1 2 6
MIRT505964 RAB5C RAB5C, member RAS oncogene family 2 6
MIRT506322 OTUD4 OTU deubiquitinase 4 2 4
MIRT506803 KLHL15 kelch like family member 15 2 6
MIRT506917 KBTBD8 kelch repeat and BTB domain containing 8 2 4
MIRT507400 EMC7 ER membrane protein complex subunit 7 2 8
MIRT507471 EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 2 6
MIRT508058 ATP13A3 ATPase 13A3 2 4
MIRT508135 AMD1 adenosylmethionine decarboxylase 1 2 2
MIRT509895 RPS23 ribosomal protein S23 2 4
MIRT510881 RAN RAN, member RAS oncogene family 2 8
MIRT513766 PEX5L peroxisomal biogenesis factor 5 like 2 4
MIRT516898 COPS8 COP9 signalosome subunit 8 2 2
MIRT518703 TIMD4 T-cell immunoglobulin and mucin domain containing 4 2 4
MIRT520429 TTPAL alpha tocopherol transfer protein like 2 6
MIRT521843 PNISR PNN interacting serine and arginine rich protein 2 4
MIRT522116 NUDT3 nudix hydrolase 3 2 4
MIRT525467 TMPRSS12 transmembrane protease, serine 12 2 2
MIRT525583 MTRNR2L7 MT-RNR2-like 7 2 2
MIRT525906 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 2 2
MIRT526072 C11orf54 chromosome 11 open reading frame 54 2 2
MIRT526232 MTRNR2L5 MT-RNR2-like 5 2 4
MIRT526455 FAM71F2 family with sequence similarity 71 member F2 2 4
MIRT526515 POU5F1B POU class 5 homeobox 1B 2 2
MIRT528032 FEZ2 fasciculation and elongation protein zeta 2 2 2
MIRT528422 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT528995 ISLR2 immunoglobulin superfamily containing leucine rich repeat 2 2 4
MIRT529311 ATRNL1 attractin like 1 2 2
MIRT529376 SKP1 S-phase kinase associated protein 1 2 4
MIRT530015 SRRM1 serine and arginine repetitive matrix 1 2 2
MIRT530089 FMN2 formin 2 2 2
MIRT530942 ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 2 2
MIRT531229 HIST1H2BD histone cluster 1 H2B family member d 2 2
MIRT533088 YTHDF3 YTH N6-methyladenosine RNA binding protein 3 2 2
MIRT533299 USP46 ubiquitin specific peptidase 46 2 2
MIRT533318 UNKL unkempt family like zinc finger 2 2
MIRT533721 TMEM30A transmembrane protein 30A 2 2
MIRT534096 AZF1 azoospermia factor 1 2 2
MIRT534188 SLC7A11 solute carrier family 7 member 11 2 2
MIRT534493 SAR1B secretion associated Ras related GTPase 1B 2 2
MIRT536077 MBOAT2 membrane bound O-acyltransferase domain containing 2 2 2
MIRT536242 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 2
MIRT537524 FAM104A family with sequence similarity 104 member A 2 2
MIRT538088 DGKH diacylglycerol kinase eta 2 2
MIRT538475 CNBP CCHC-type zinc finger nucleic acid binding protein 2 2
MIRT538853 BTG1 BTG anti-proliferation factor 1 2 4
MIRT539075 GDNF glial cell derived neurotrophic factor 2 2
MIRT539480 ACVR2B activin A receptor type 2B 2 4
MIRT540210 ARHGAP18 Rho GTPase activating protein 18 2 2
MIRT541940 TSPAN2 tetraspanin 2 2 2
MIRT543812 COCH cochlin 2 2
MIRT545120 PDZRN4 PDZ domain containing ring finger 4 2 2
MIRT545571 GIMAP4 GTPase, IMAP family member 4 2 2
MIRT545989 XKR4 XK related 4 2 2
MIRT547213 PANK3 pantothenate kinase 3 2 4
MIRT547740 KIAA1468 KIAA1468 2 2
MIRT548022 GRB2 growth factor receptor bound protein 2 2 4
MIRT548032 GOLIM4 golgi integral membrane protein 4 2 2
MIRT548102 GFPT1 glutamine--fructose-6-phosphate transaminase 1 2 4
MIRT548217 FKBP1A FK506 binding protein 1A 2 2
MIRT548588 DDX3X DEAD-box helicase 3, X-linked 2 4
MIRT548953 CDC27 cell division cycle 27 2 2
MIRT549072 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT550368 INCENP inner centromere protein 2 6
MIRT550546 MYZAP myocardial zonula adherens protein 2 2
MIRT551491 TMEM192 transmembrane protein 192 2 4
MIRT553078 UEVLD UEV and lactate/malate dehyrogenase domains 2 2
MIRT554104 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT555127 PTPRG protein tyrosine phosphatase, receptor type G 2 2
MIRT555477 POC1B-GALNT4 POC1B-GALNT4 readthrough 2 2
MIRT555978 NPTN neuroplastin 2 2
MIRT557011 HPRT1 hypoxanthine phosphoribosyltransferase 1 2 2
MIRT557706 GALNT4 polypeptide N-acetylgalactosaminyltransferase 4 2 2
MIRT558333 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 4
MIRT558488 DBN1 drebrin 1 2 2
MIRT559942 ZNF567 zinc finger protein 567 2 2
MIRT561127 ATP2B1 ATPase plasma membrane Ca2+ transporting 1 2 2
MIRT561791 PAWR pro-apoptotic WT1 regulator 2 2
MIRT562438 EEF2 eukaryotic translation elongation factor 2 2 2
MIRT563102 PABPC4L poly(A) binding protein cytoplasmic 4 like 2 2
MIRT563212 ZNF813 zinc finger protein 813 2 2
MIRT563426 KIF3A kinesin family member 3A 2 2
MIRT563473 SPIN4 spindlin family member 4 2 2
MIRT564015 HSPA4 heat shock protein family A (Hsp70) member 4 2 4
MIRT564117 ZYG11B zyg-11 family member B, cell cycle regulator 2 2
MIRT564223 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT564503 CACNG1 calcium voltage-gated channel auxiliary subunit gamma 1 2 2
MIRT564515 DUSP3 dual specificity phosphatase 3 2 2
MIRT564811 ZBTB21 zinc finger and BTB domain containing 21 2 2
MIRT565265 TPD52 tumor protein D52 2 2
MIRT566012 RHOB ras homolog family member B 2 2
MIRT566216 PTMA prothymosin, alpha 2 2
MIRT566638 NFYA nuclear transcription factor Y subunit alpha 2 2
MIRT566821 MAPK8 mitogen-activated protein kinase 8 2 2
MIRT566948 LEPROT leptin receptor overlapping transcript 2 2
MIRT567290 HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 2 2
MIRT567895 CSTF2 cleavage stimulation factor subunit 2 2 2
MIRT568731 MTRNR2L3 MT-RNR2-like 3 2 2
MIRT571263 ZNF239 zinc finger protein 239 2 2
MIRT572593 EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 2 2
MIRT573827 TGOLN2 trans-golgi network protein 2 2 2
MIRT576391 Fhl2 four and a half LIM domains 2 2 2
MIRT609901 SMS spermine synthase 2 2
MIRT613710 ELMSAN1 ELM2 and Myb/SANT domain containing 1 2 2
MIRT614406 ADAT1 adenosine deaminase, tRNA specific 1 2 2
MIRT615042 DCX doublecortin 2 2
MIRT617514 C5orf45 MRN complex interacting protein 2 2
MIRT619476 PRDM10 PR/SET domain 10 2 2
MIRT620349 TLN1 talin 1 2 2
MIRT620910 PLA2G7 phospholipase A2 group VII 2 2
MIRT622131 SP4 Sp4 transcription factor 2 2
MIRT622955 OTUD7B OTU deubiquitinase 7B 2 2
MIRT623351 MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 2 2
MIRT623619 INTU inturned planar cell polarity protein 2 2
MIRT624409 CCDC171 coiled-coil domain containing 171 2 2
MIRT625171 CCS copper chaperone for superoxide dismutase 2 2
MIRT625685 RPP40 ribonuclease P/MRP subunit p40 2 2
MIRT625875 ALDH18A1 aldehyde dehydrogenase 18 family member A1 2 2
MIRT626002 FAM107A family with sequence similarity 107 member A 2 2
MIRT626872 HRH4 histamine receptor H4 2 4
MIRT628220 FKBP9 FK506 binding protein 9 2 2
MIRT628265 DIO2 iodothyronine deiodinase 2 2 2
MIRT628402 C8orf37 chromosome 8 open reading frame 37 2 2
MIRT630564 C3orf36 chromosome 3 open reading frame 36 2 4
MIRT631577 RASSF9 Ras association domain family member 9 2 2
MIRT635730 CCDC58 coiled-coil domain containing 58 2 2
MIRT636224 SLC8A1 solute carrier family 8 member A1 2 2
MIRT636613 CLIC5 chloride intracellular channel 5 2 2
MIRT638899 CDK9 cyclin dependent kinase 9 2 2
MIRT640167 ATXN7L1 ataxin 7 like 1 2 2
MIRT642070 GTDC1 glycosyltransferase like domain containing 1 2 2
MIRT643034 CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 2 2
MIRT644572 SPOP speckle type BTB/POZ protein 2 2
MIRT644954 IFNB1 interferon beta 1 2 2
MIRT645948 TTF2 transcription termination factor 2 2 2
MIRT646440 XRCC2 X-ray repair cross complementing 2 2 2
MIRT647896 EPN2 epsin 2 2 2
MIRT648276 ZNF582 zinc finger protein 582 2 2
MIRT649381 NEDD1 neural precursor cell expressed, developmentally down-regulated 1 2 2
MIRT650254 CD68 CD68 molecule 2 2
MIRT650333 ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B) 2 2
MIRT651707 VMP1 vacuole membrane protein 1 2 2
MIRT651774 VASP vasodilator stimulated phosphoprotein 2 2
MIRT653144 SRPK2 SRSF protein kinase 2 2 2
MIRT654112 RPS6KA5 ribosomal protein S6 kinase A5 2 2
MIRT654161 RORB RAR related orphan receptor B 2 2
MIRT655716 MLF2 myeloid leukemia factor 2 2 2
MIRT657476 HDAC4 histone deacetylase 4 2 2
MIRT658095 FOXO1 forkhead box O1 2 2
MIRT658860 DTX3L deltex E3 ubiquitin ligase 3L 2 2
MIRT658988 DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 2 2
MIRT660767 ALDH6A1 aldehyde dehydrogenase 6 family member A1 2 2
MIRT661622 C2orf15 chromosome 2 open reading frame 15 2 2
MIRT661694 TFDP2 transcription factor Dp-2 2 2
MIRT662208 PLA2G4E phospholipase A2 group IVE 2 2
MIRT662443 RALGAPA1 Ral GTPase activating protein catalytic alpha subunit 1 2 2
MIRT664422 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2 2
MIRT687505 NECAB1 N-terminal EF-hand calcium binding protein 1 2 2
MIRT689910 SOD2 superoxide dismutase 2 2 2
MIRT690781 PLA2G2C phospholipase A2 group IIC 2 2
MIRT698488 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT699685 SFMBT2 Scm like with four mbt domains 2 2 2
MIRT700926 PDS5A PDS5 cohesin associated factor A 2 2
MIRT702258 LMNB1 lamin B1 2 2
MIRT703166 GPR137C G protein-coupled receptor 137C 2 2
MIRT703242 GNS glucosamine (N-acetyl)-6-sulfatase 2 2
MIRT704737 CENPQ centromere protein Q 2 2
MIRT707310 GLRX2 glutaredoxin 2 2 2
MIRT710021 KCNQ5 potassium voltage-gated channel subfamily Q member 5 2 2
MIRT712212 SCOC short coiled-coil protein 2 2
MIRT714742 SETBP1 SET binding protein 1 2 2
MIRT718268 ZNF749 zinc finger protein 749 2 2
MIRT720553 DYRK4 dual specificity tyrosine phosphorylation regulated kinase 4 2 2
MIRT722248 RBM41 RNA binding motif protein 41 2 2
MIRT723767 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT723977 KIAA0146 scaffolding protein involved in DNA repair 1 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4282 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4282 Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-4282 Neoadjuvant chemotherapy sensitive tissue (breast cancer)

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