miRTarBase - #MIRT076823


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pre-miRNA Information
pre-miRNA hsa-mir-548ac   
Genomic Coordinates chr1: 116560024 - 116560111
Description Homo sapiens miR-548ac stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-548ac
Sequence 53| CAAAAACCGGCAAUUACUUUUG |74
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 4 1 - 116560056 29233923 MiREDiBase
A-to-I 5 1 - 116560055 29233923 MiREDiBase
A-to-I 6 1 - 116560054 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1182074110 6 dbSNP
rs1392446444 6 dbSNP
rs1326234665 7 dbSNP
rs556579863 8 dbSNP
rs993390910 9 dbSNP
rs901450363 13 dbSNP
rs538553306 22 dbSNP
Putative Targets

Gene Information
Gene Symbol SUZ12   
Synonyms CHET9, JJAZ1
Description SUZ12 polycomb repressive complex 2 subunit
Transcript NM_015355   
Expression
Putative miRNA Targets on SUZ12
3'UTR of SUZ12
(miRNA target sites are highlighted)		 
>SUZ12|NM_015355|3'UTR
   1 AAAGCTCTAACCCCATGTTATGGACAAACACTGAAATTACATTTTAGGGAATTCATCCTCTAAGAATTATGTTTTTGTTT
  81 TTAATCATATGTTCCAAACAGGCACTGTTAGATGAAGTAAATGATTTCAACAAGGATATTTGTATCAGGGTTCTACTTCA
 161 CTTCATTATGCAGCATTACATGTATATCACTTTTATTGATGTCATTAAAACATTCTGTACTTTAAGCATGAAAAGCAATA
 241 TTTCAAAGTATTTTTAAACTCAACAAATGTCATCAAATATGTTGAATTGATCTAGAAATTATTTCATATATAAATCAGAA
 321 TTTTTTTGCATTTATGAACGGCTGTTTTTCTACTTTGTAATTGTGAGACATTTTCTTGGGGAGGGAAAATTGGAATGGTT
 401 CCCTTTTTTAGAAATTGAAGTGGTCTTCATATGTCAACTACAGAAAAGGAAAAAAATAGAAATTGAAGGATTTTTATGAA
 481 ATTATATTGCATTACTATTTGCAGTCAAACTTTGATCCTTGTTTTTGAAATCATTTGTCAATTCGGAATGAAAAATTATA
 561 ATGTAATTTTACATTACATAAGTTCCTTTTACAATTAAAAAATAGCACTTCTTCATCTTATGCCTGTTTGAGAAGATATT
 641 AAATTTTCACATTGTTGACAGTGAAATGCTATGTTGGTTTATAAGATTACAGACCATTTGTTTTCATGTGGATAATTTTA
 721 GTGCATTGCTCACCCGGTATGTTTTTTTTTTTTAACTTGAACATTTTGCTTGTTTTGTTTTTCTTTTTTAATTAGATAAT
 801 CACACGGAAAATTAAGCTGTTCATATCTTTAAATTAGGATTGCAAACCAAGGAAAGAACGCATTTGAGATTTTAAGATGT
 881 CACTTATAAGGGGAGAAGTGTTCTTAAAAAGTCAACCAGAAAACTGTTATGCCTTTTATTTGTTTGCAAGGATGTCTTTG
 961 TAATGTGTTTCATGAATAGAATATCCAATAGAGATAAGCTGACTTGAATCATTTTGAGCAATTTTGCCCTGTGTTATATG
1041 TGTTTCACGCACATATTTGCAGTTGGATTTTCTCCAACAGAAAGTGGATTCACTACTGGCACATTAACAAGCACCAATAG
1121 GTTTTTATTCCAACTCCGAGCACTGTGGTTGAGTAACATCACCTCAATTTTTTATTATCCTTAAAGATATTGCATTTTCA
1201 TATTCTTTATTTATAAAGGATCAATGCTGCTGTAAATACAGGTATTTTTAATTTTAAAATTTCATTCCACCACCATCAGA
1281 TGCAGTTCCCTATTTTGTTTAATGAAGGGATATATAAGCTTTCTAATGGTGTCTTCAGAAATTTATAAAATGTAAATACT
1361 GATTTGACTGGTCTTTAAGATGTGTTTAACTGTGAGGCTATTTAACGAATAGTGTGGATGTGATTTGTCATCCAGTATTA
1441 AGTTCTTAGTCATTGATTTTTGTGTTTAAAAAAAAATAGGAAAGAGGGAAACTGCAGCTTTCATTACAGATTCCTTGATT
1521 GGTAAGCTCTCCAAATGATGAGTTCTAGTAAACTCTGATTTTTGCCTCTGGATAGTAGATCTCGAGCGTTTATCTCGGGC
1601 TTTAATTTGCTAAAGCTGTGCACATATGTAAAAAAAAAAAAAAAAAGATTATTTTAGGGGAGATGTAGGTGTAGAATTAT
1681 TGCTTATGTCATTTCTTAAGCAGTTATGCTCTTAATGCTTAAAAGAAGGCTAGCATTGTTTGCACAAAAAGTTGGTGATT
1761 CCCACCCCAAATAGTAATAAAATTACTTCTGTTGAGTAAACTTTTTATGTCATCGTAAAAGCTGAAAAAATCCCTTTGTT
1841 TCTATTTATAAAAAAAGTGCTTTTCTATATGTACCCTTGATAACAGATTTTGAAGAAATCCTGTAAGATGATAAAGCATT
1921 TGAATGGTACAGTAGATGTAAAAAAAATTCAGTTTAAAAGAACATTTGTTTTTACATTAAATGTTTATTTGAAATCAAAT
2001 GATTTTGTACATAAAGTTCAATAATATAAAAGCTGTATTCTGAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' guuUUCAUUAACGGCCAAAAAc 5'
             ||| |    : ||||||| 
Target 5' aacAAGCACCAATAGGTTTTTa 3'
 1106 - 1127 143.00 -5.07
2 
miRNA  3' guUUUCAUUAACGGCCAAAAAc 5'
            | || |||||  || |||| 
Target 5' aaATAGAAATTGAAGGATTTTt 3'
 454 - 475 136.00 -8.50
3 
miRNA  3' guuuUCAUUAACGGCCAAAAAc 5'
              |||||   |:| ||||| 
Target 5' ttctAGTAAACTCTGATTTTTg 3'
 1543 - 1564 130.00 -8.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30474500 14 COSMIC
COSN30459407 15 COSMIC
COSN30473508 15 COSMIC
COSN31606965 44 COSMIC
COSN31496038 55 COSMIC
COSN31541561 59 COSMIC
COSN20213400 112 COSMIC
COSN4905681 272 COSMIC
COSN20303264 376 COSMIC
COSN27389052 507 COSMIC
COSN8834638 653 COSMIC
COSN20879481 664 COSMIC
COSN20113794 754 COSMIC
COSN29065233 754 COSMIC
COSN15681540 764 COSMIC
COSN30228877 982 COSMIC
COSN16016993 1144 COSMIC
COSN1716674 1222 COSMIC
COSN8834639 1299 COSMIC
COSN22895472 1394 COSMIC
COSN23363554 1643 COSMIC
COSN28486902 1652 COSMIC
COSN26574617 1659 COSMIC
COSN31486517 1762 COSMIC
COSN19419575 1808 COSMIC
COSN30543545 1860 COSMIC
COSN31491212 1923 COSMIC
COSN29282068 1948 COSMIC
COSN31521853 1953 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1164962849 5 dbSNP
rs773478718 8 dbSNP
rs1455150939 9 dbSNP
rs1238101630 11 dbSNP
rs760864590 16 dbSNP
rs765020343 20 dbSNP
rs752541997 22 dbSNP
rs1433798715 23 dbSNP
rs990773706 28 dbSNP
rs370088626 33 dbSNP
rs764147751 34 dbSNP
rs751589879 38 dbSNP
rs756787684 46 dbSNP
rs1206850998 48 dbSNP
rs1463165421 56 dbSNP
rs1228714607 58 dbSNP
rs1333888402 61 dbSNP
rs968611418 67 dbSNP
rs564362901 71 dbSNP
rs970598920 72 dbSNP
rs1000421702 91 dbSNP
rs972592405 95 dbSNP
rs1472786928 103 dbSNP
rs918390606 106 dbSNP
rs1343894769 108 dbSNP
rs143901922 110 dbSNP
rs958886693 116 dbSNP
rs992671133 127 dbSNP
rs1323144717 134 dbSNP
rs931425255 135 dbSNP
rs1161797210 147 dbSNP
rs866016404 149 dbSNP
rs961686593 151 dbSNP
rs1425748035 152 dbSNP
rs971820636 156 dbSNP
rs1386453436 166 dbSNP
rs1185955455 168 dbSNP
rs1474475604 175 dbSNP
rs1243709135 176 dbSNP
rs1209271988 177 dbSNP
rs1041317331 183 dbSNP
rs1271007553 188 dbSNP
rs920324782 190 dbSNP
rs930850260 196 dbSNP
rs567169620 197 dbSNP
rs767689487 199 dbSNP
rs904661823 200 dbSNP
rs577897786 201 dbSNP
rs1297770758 203 dbSNP
rs1394443986 205 dbSNP
rs1324251566 215 dbSNP
rs1459785745 221 dbSNP
rs115308907 224 dbSNP
rs1170013762 229 dbSNP
rs944945256 230 dbSNP
rs543743287 239 dbSNP
rs1189348916 244 dbSNP
rs1453684885 246 dbSNP
rs1352599026 247 dbSNP
rs1192653572 252 dbSNP
rs1488687482 256 dbSNP
rs1201993176 261 dbSNP
rs892507988 261 dbSNP
rs1308944005 262 dbSNP
rs541061444 264 dbSNP
rs1061194 266 dbSNP
rs945347998 275 dbSNP
rs1043842127 277 dbSNP
rs1228554033 282 dbSNP
rs1011926678 290 dbSNP
rs1370839576 292 dbSNP
rs1024605143 307 dbSNP
rs903957071 311 dbSNP
rs563131051 317 dbSNP
rs1298022053 321 dbSNP
rs1368742950 321 dbSNP
rs113398624 334 dbSNP
rs15654 339 dbSNP
rs894270084 340 dbSNP
rs1025503035 341 dbSNP
rs1393122737 346 dbSNP
rs201628524 351 dbSNP
rs548702896 353 dbSNP
rs1178140192 354 dbSNP
rs1249535295 355 dbSNP
rs1433763740 355 dbSNP
rs1442312772 356 dbSNP
rs1186079615 357 dbSNP
rs1234904325 360 dbSNP
rs952637381 371 dbSNP
rs1345120159 373 dbSNP
rs1014166205 382 dbSNP
rs1236053053 384 dbSNP
rs1313346628 391 dbSNP
rs748643898 395 dbSNP
rs16967070 406 dbSNP
rs1177203411 420 dbSNP
rs1401623634 429 dbSNP
rs1308871532 430 dbSNP
rs1414468401 437 dbSNP
rs976726068 438 dbSNP
rs922583828 440 dbSNP
rs946334817 442 dbSNP
rs1042350460 448 dbSNP
rs1156605035 450 dbSNP
rs1412157547 450 dbSNP
rs1413787399 450 dbSNP
rs904727930 454 dbSNP
rs1484519105 455 dbSNP
rs563330304 458 dbSNP
rs1200573090 465 dbSNP
rs1483840804 466 dbSNP
rs1260668672 472 dbSNP
rs971686110 488 dbSNP
rs1337537559 491 dbSNP
rs1289437493 495 dbSNP
rs1410196268 496 dbSNP
rs1232879673 501 dbSNP
rs1287543497 512 dbSNP
rs1353847275 522 dbSNP
rs1314895359 525 dbSNP
rs1396696749 536 dbSNP
rs1027298146 540 dbSNP
rs529133391 542 dbSNP
rs951899352 545 dbSNP
rs1225002520 546 dbSNP
rs777793601 548 dbSNP
rs1389084356 550 dbSNP
rs985861851 560 dbSNP
rs1474003198 562 dbSNP
rs548845540 563 dbSNP
rs1369868367 564 dbSNP
rs116124238 570 dbSNP
rs528387739 579 dbSNP
rs1259138313 593 dbSNP
rs906177480 595 dbSNP
rs572457257 597 dbSNP
rs551336112 607 dbSNP
rs944852439 608 dbSNP
rs1483699446 612 dbSNP
rs749321410 615 dbSNP
rs1181879427 626 dbSNP
rs1250114619 627 dbSNP
rs79896497 628 dbSNP
rs528208136 640 dbSNP
rs1005806291 642 dbSNP
rs1018023498 643 dbSNP
rs1377082663 643 dbSNP
rs1464607454 644 dbSNP
rs1325923435 650 dbSNP
rs1295565280 652 dbSNP
rs1169787100 670 dbSNP
rs914139853 671 dbSNP
rs945589660 672 dbSNP
rs148348149 673 dbSNP
rs1459697424 681 dbSNP
rs976778341 682 dbSNP
rs759421080 684 dbSNP
rs903818254 686 dbSNP
rs1307141648 690 dbSNP
rs1370824179 694 dbSNP
rs186993715 695 dbSNP
rs1249218249 701 dbSNP
rs1193328592 707 dbSNP
rs1055213289 713 dbSNP
rs1406334297 713 dbSNP
rs1292551126 732 dbSNP
rs141497489 734 dbSNP
rs977734905 735 dbSNP
rs1230417062 736 dbSNP
rs1014028859 737 dbSNP
rs1024199017 738 dbSNP
rs936224558 740 dbSNP
rs772029372 741 dbSNP
rs1429847224 742 dbSNP
rs796203928 742 dbSNP
rs1391248403 745 dbSNP
rs1272869705 755 dbSNP
rs1490946295 756 dbSNP
rs1210589456 757 dbSNP
rs1266927964 760 dbSNP
rs551572826 762 dbSNP
rs536876490 780 dbSNP
rs1200072093 784 dbSNP
rs1248793879 784 dbSNP
rs867074783 785 dbSNP
rs553685000 790 dbSNP
rs537166 806 dbSNP
rs545736350 807 dbSNP
rs1167901587 823 dbSNP
rs951704419 824 dbSNP
rs994231967 825 dbSNP
rs774584355 826 dbSNP
rs1293951353 844 dbSNP
rs1309195657 846 dbSNP
rs1275183299 851 dbSNP
rs1238092627 854 dbSNP
rs1348181716 857 dbSNP
rs1389534421 859 dbSNP
rs1410122884 860 dbSNP
rs779415634 861 dbSNP
rs1384753427 867 dbSNP
rs1017345316 868 dbSNP
rs1319671141 877 dbSNP
rs1046694168 884 dbSNP
rs1173471903 888 dbSNP
rs966225788 888 dbSNP
rs1469958350 891 dbSNP
rs976267590 894 dbSNP
rs1410302085 899 dbSNP
rs914046588 906 dbSNP
rs888364050 911 dbSNP
rs1256860508 913 dbSNP
rs537326268 917 dbSNP
rs1005404281 918 dbSNP
rs1296051558 921 dbSNP
rs1204261279 929 dbSNP
rs1279265445 929 dbSNP
rs1362292707 931 dbSNP
rs1245959179 933 dbSNP
rs1018079413 936 dbSNP
rs1265269406 939 dbSNP
rs963834731 940 dbSNP
rs1487605777 950 dbSNP
rs1449613151 957 dbSNP
rs1361345364 959 dbSNP
rs557738780 961 dbSNP
rs1207146237 965 dbSNP
rs1386886038 972 dbSNP
rs1161877905 982 dbSNP
rs966961243 989 dbSNP
rs550923 992 dbSNP
rs567452079 993 dbSNP
rs925315288 996 dbSNP
rs938019711 1001 dbSNP
rs1473822097 1008 dbSNP
rs1055647990 1014 dbSNP
rs917981560 1019 dbSNP
rs949446289 1021 dbSNP
rs1165173810 1022 dbSNP
rs1045554025 1028 dbSNP
rs991727501 1032 dbSNP
rs1229468509 1034 dbSNP
rs897629360 1037 dbSNP
rs916105052 1039 dbSNP
rs993821929 1049 dbSNP
rs1269131278 1050 dbSNP
rs1160942848 1052 dbSNP
rs1388641375 1053 dbSNP
rs1433704169 1055 dbSNP
rs1048966883 1074 dbSNP
rs1046214778 1079 dbSNP
rs763842302 1087 dbSNP
rs1458112342 1091 dbSNP
rs191480323 1094 dbSNP
rs1162945598 1096 dbSNP
rs1407348162 1097 dbSNP
rs1414595466 1101 dbSNP
rs1188047509 1109 dbSNP
rs555494612 1115 dbSNP
rs1007210322 1118 dbSNP
rs1241376207 1129 dbSNP
rs1188899309 1135 dbSNP
rs1017259191 1138 dbSNP
rs1223285685 1139 dbSNP
rs776595555 1141 dbSNP
rs761722809 1143 dbSNP
rs1271632159 1144 dbSNP
rs1225575147 1152 dbSNP
rs1340591718 1162 dbSNP
rs1300458023 1164 dbSNP
rs1436556573 1168 dbSNP
rs1292194847 1183 dbSNP
rs1367325269 1183 dbSNP
rs1328812267 1187 dbSNP
rs1438836762 1190 dbSNP
rs765094854 1191 dbSNP
rs1245081259 1195 dbSNP
rs1427916729 1196 dbSNP
rs997235625 1201 dbSNP
rs1039580504 1206 dbSNP
rs1432572713 1211 dbSNP
rs1255145979 1214 dbSNP
rs1422763235 1215 dbSNP
rs1192739600 1219 dbSNP
rs1021137499 1230 dbSNP
rs749918460 1234 dbSNP
rs1326026258 1243 dbSNP
rs1202325745 1261 dbSNP
rs563425192 1269 dbSNP
rs372363455 1276 dbSNP
rs1483750229 1277 dbSNP
rs1184156921 1293 dbSNP
rs10627 1298 dbSNP
rs757880184 1300 dbSNP
rs1274811984 1310 dbSNP
rs1412223906 1311 dbSNP
rs150884111 1312 dbSNP
rs1312159139 1314 dbSNP
rs1029457068 1315 dbSNP
rs1156268646 1315 dbSNP
rs1360412787 1321 dbSNP
rs959659948 1324 dbSNP
rs765979197 1330 dbSNP
rs185207156 1337 dbSNP
rs760512897 1347 dbSNP
rs775087254 1347 dbSNP
rs370370499 1352 dbSNP
rs1372470752 1365 dbSNP
rs917888336 1370 dbSNP
rs949478961 1372 dbSNP
rs1375883130 1381 dbSNP
rs1177897067 1386 dbSNP
rs1033455270 1393 dbSNP
rs957338995 1396 dbSNP
rs1473395099 1397 dbSNP
rs1037036219 1407 dbSNP
rs919129282 1408 dbSNP
rs559146384 1426 dbSNP
rs1199415770 1430 dbSNP
rs1412053218 1438 dbSNP
rs1254778310 1440 dbSNP
rs1212601111 1446 dbSNP
rs991778431 1452 dbSNP
rs1288180870 1454 dbSNP
rs929145129 1458 dbSNP
rs1023215581 1468 dbSNP
rs528324546 1468 dbSNP
rs971605908 1468 dbSNP
rs551274913 1476 dbSNP
rs1304511788 1478 dbSNP
rs1350065149 1480 dbSNP
rs981610288 1486 dbSNP
rs1049477724 1487 dbSNP
rs1387614192 1493 dbSNP
rs1156730678 1494 dbSNP
rs1458448064 1499 dbSNP
rs887720907 1506 dbSNP
rs1312860975 1518 dbSNP
rs566138053 1519 dbSNP
rs929731073 1520 dbSNP
rs965322735 1522 dbSNP
rs1257738645 1524 dbSNP
rs909564900 1529 dbSNP
rs1462193197 1533 dbSNP
rs1267852948 1536 dbSNP
rs1207248575 1546 dbSNP
rs1331417505 1561 dbSNP
rs1261535816 1567 dbSNP
rs751194002 1572 dbSNP
rs1038729241 1579 dbSNP
rs941030044 1584 dbSNP
rs1206996372 1588 dbSNP
rs565128954 1589 dbSNP
rs901472314 1597 dbSNP
rs1364408164 1598 dbSNP
rs530977747 1599 dbSNP
rs1252312119 1600 dbSNP
rs550773014 1601 dbSNP
rs746460676 1604 dbSNP
rs190103141 1617 dbSNP
rs1433264523 1619 dbSNP
rs1162277602 1620 dbSNP
rs1174821202 1624 dbSNP
rs1369669430 1629 dbSNP
rs933884436 1629 dbSNP
rs1051381204 1630 dbSNP
rs1209448056 1630 dbSNP
rs1246828790 1630 dbSNP
rs1267254544 1630 dbSNP
rs1341297048 1630 dbSNP
rs1445714716 1630 dbSNP
rs769296762 1630 dbSNP
rs903003221 1630 dbSNP
rs1295316297 1631 dbSNP
rs79440966 1632 dbSNP
rs76286598 1633 dbSNP
rs1437272344 1642 dbSNP
rs1357909300 1645 dbSNP
rs1322705231 1647 dbSNP
rs997305725 1648 dbSNP
rs1392458487 1649 dbSNP
rs768356633 1650 dbSNP
rs1293544911 1661 dbSNP
rs1428545414 1667 dbSNP
rs536758732 1671 dbSNP
rs755443721 1672 dbSNP
rs1387858233 1681 dbSNP
rs1167252169 1691 dbSNP
rs1020708998 1703 dbSNP
rs902709797 1708 dbSNP
rs1033094104 1710 dbSNP
rs1450032041 1712 dbSNP
rs751708465 1712 dbSNP
rs1223229882 1723 dbSNP
rs776206287 1729 dbSNP
rs1012931710 1730 dbSNP
rs1272641954 1742 dbSNP
rs1230492368 1761 dbSNP
rs138206560 1765 dbSNP
rs567073047 1772 dbSNP
rs981689133 1773 dbSNP
rs1276833274 1783 dbSNP
rs1332398546 1784 dbSNP
rs1368654772 1790 dbSNP
rs139740652 1791 dbSNP
rs1026930360 1805 dbSNP
rs1368140716 1812 dbSNP
rs144547379 1815 dbSNP
rs982979878 1816 dbSNP
rs990996922 1830 dbSNP
rs1172296468 1835 dbSNP
rs577544062 1851 dbSNP
rs1310327838 1861 dbSNP
rs970697326 1863 dbSNP
rs1200392820 1866 dbSNP
rs756691982 1868 dbSNP
rs1275013740 1869 dbSNP
rs1482610357 1870 dbSNP
rs577697842 1872 dbSNP
rs972824097 1873 dbSNP
rs1249672250 1874 dbSNP
rs918656200 1875 dbSNP
rs941074176 1880 dbSNP
rs1277837393 1883 dbSNP
rs1488633409 1885 dbSNP
rs537084694 1889 dbSNP
rs1190087976 1895 dbSNP
rs1422477844 1900 dbSNP
rs1227367252 1906 dbSNP
rs1451824964 1911 dbSNP
rs929153846 1917 dbSNP
rs1289632461 1923 dbSNP
rs1442310957 1932 dbSNP
rs1336798107 1933 dbSNP
rs984656011 1935 dbSNP
rs1413322256 1940 dbSNP
rs975066104 1940 dbSNP
rs920898727 1941 dbSNP
rs909007426 1949 dbSNP
rs1428214939 1950 dbSNP
rs1456875854 1953 dbSNP
rs1229905300 1964 dbSNP
rs1410051848 1969 dbSNP
rs556699968 1972 dbSNP
rs943305740 1987 dbSNP
rs1470551845 1998 dbSNP
rs1237036949 2002 dbSNP
rs1185305359 2008 dbSNP
rs1444106250 2012 dbSNP
rs1326014674 2014 dbSNP
rs1207904906 2020 dbSNP
rs1326568040 2022 dbSNP
rs573653847 2022 dbSNP
rs1038967830 2024 dbSNP
rs1355018215 2025 dbSNP
rs1281970264 2028 dbSNP
rs1446420003 2032 dbSNP
rs542319919 2033 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 23512.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_015355 | 3UTR | UCAUCCUCUAAGAAUUAUGUUUUUGUUUUUAAUCAUAUGUUCCAAACAGGCACUGUUAGAUGAAGUAAAUGAUUUCAACAAGGAUAUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_015355 | 3UTR | GAAUUCAUCCUCUAAGAAUUAUGUUUUUGUUUUUAAUCAUAUGUUCCAAACAGGCACUGUUAGAUGAAGUAAAUGAUUUCAACAAGGAUAUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_015355 | 3UTR | AAACACUGAAAUUACAUUUUAGGGAAUUCAUCCUCUAAGAAUUAUGUUUUUGUUUUUAAUCAUAUGUUCCAAACAGGCACUGUUAGAUGAAGUAAAUGAUUUCAACAAGGAUAUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_015355 | 3UTR | AUUAUGUUUUUGUUUUUAAUCAUAUGUUCCAAACAGGCACUGUUAGAUGAAGUAAAUGAUUUCAACAAGGAUAUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_015355 | 3UTR | UUUGUUUUUAAUCAUAUGUUCCAAACAGGCACUGUUAGAUGAAGUAAAUGAUUUCAACAAGGAUAUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000322652.5 | 3UTR | UUUUUAUUCCAACUCCGAGCACUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000322652.5 | 3UTR | UUUUUAUUCCAACUCCGAGCACUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
275 hsa-miR-548ac Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055863 BUB3 BUB3, mitotic checkpoint protein 2 2
MIRT074959 LEPROT leptin receptor overlapping transcript 2 2
MIRT076823 SUZ12 SUZ12 polycomb repressive complex 2 subunit 2 4
MIRT078708 LLGL2 LLGL2, scribble cell polarity complex component 2 2
MIRT099610 ID4 inhibitor of DNA binding 4, HLH protein 2 4
MIRT103362 CBX3 chromobox 3 2 2
MIRT111801 MPZL1 myelin protein zero like 1 2 2
MIRT114050 AKAP11 A-kinase anchoring protein 11 2 12
MIRT133719 SKI SKI proto-oncogene 2 2
MIRT136817 NHLRC3 NHL repeat containing 3 2 6
MIRT149926 LDLR low density lipoprotein receptor 2 2
MIRT166915 TNPO1 transportin 1 2 2
MIRT168142 SOX4 SRY-box 4 2 10
MIRT190787 STRN3 striatin 3 2 4
MIRT207471 RMND5A required for meiotic nuclear division 5 homolog A 2 2
MIRT250951 CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 2 4
MIRT271993 ARF1 ADP ribosylation factor 1 2 4
MIRT282618 IGF1R insulin like growth factor 1 receptor 2 8
MIRT294153 ZNF845 zinc finger protein 845 2 2
MIRT309060 C4ORF3 chromosome 4 open reading frame 3 2 2
MIRT318548 SYNCRIP synaptotagmin binding cytoplasmic RNA interacting protein 2 2
MIRT319752 LUC7L2 LUC7 like 2, pre-mRNA splicing factor 2 2
MIRT331324 TM9SF3 transmembrane 9 superfamily member 3 2 2
MIRT337204 TOMM20 translocase of outer mitochondrial membrane 20 2 6
MIRT346145 ALYREF Aly/REF export factor 2 2
MIRT347727 LSM14A LSM14A, mRNA processing body assembly factor 2 2
MIRT350503 MRGBP MRG domain binding protein 2 6
MIRT356409 RBPJ recombination signal binding protein for immunoglobulin kappa J region 2 2
MIRT357986 GRPEL2 GrpE like 2, mitochondrial 2 2
MIRT374399 M6PR mannose-6-phosphate receptor, cation dependent 2 6
MIRT442727 TMEM158 transmembrane protein 158 (gene/pseudogene) 2 2
MIRT443411 HMX3 H6 family homeobox 3 2 2
MIRT444408 FRMD5 FERM domain containing 5 2 2
MIRT444469 PTPRG protein tyrosine phosphatase, receptor type G 2 2
MIRT444650 HSBP1 heat shock factor binding protein 1 2 2
MIRT444861 EXD2 exonuclease 3'-5' domain containing 2 2 2
MIRT445685 TNFSF15 TNF superfamily member 15 2 2
MIRT446001 CD1D CD1d molecule 2 2
MIRT446074 RABIF RAB interacting factor 2 2
MIRT446308 ACSL3 acyl-CoA synthetase long chain family member 3 2 2
MIRT446432 ABHD2 abhydrolase domain containing 2 2 2
MIRT447269 C3orf30 chromosome 3 open reading frame 30 2 2
MIRT447759 TMCC3 transmembrane and coiled-coil domain family 3 2 2
MIRT448161 P2RY10 purinergic receptor P2Y10 2 2
MIRT449049 ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 2 2
MIRT449275 PALM2 paralemmin 2 2 2
MIRT450122 IMP3 IMP3, U3 small nucleolar ribonucleoprotein 2 2
MIRT450155 GABRB3 gamma-aminobutyric acid type A receptor beta3 subunit 2 2
MIRT451289 ZNF101 zinc finger protein 101 2 2
MIRT459253 ADRBK1 G protein-coupled receptor kinase 2 2 2
MIRT462554 NUDT19 nudix hydrolase 19 2 2
MIRT464470 UGCG UDP-glucose ceramide glucosyltransferase 2 2
MIRT465120 TSC22D2 TSC22 domain family member 2 2 4
MIRT467996 SKIL SKI like proto-oncogene 2 2
MIRT468718 SDC4 syndecan 4 2 2
MIRT469269 RHOB ras homolog family member B 2 2
MIRT470675 POLR2D RNA polymerase II subunit D 2 4
MIRT470723 POGK pogo transposable element derived with KRAB domain 2 2
MIRT471438 PDIA6 protein disulfide isomerase family A member 6 2 2
MIRT471502 PDE4D phosphodiesterase 4D 2 4
MIRT471988 NR2F2 nuclear receptor subfamily 2 group F member 2 2 4
MIRT472386 NEK7 NIMA related kinase 7 2 2
MIRT475028 KANSL1 KAT8 regulatory NSL complex subunit 1 2 8
MIRT479411 CDKN1B cyclin dependent kinase inhibitor 1B 2 10
MIRT480514 C11orf57 chromosome 11 open reading frame 57 2 2
MIRT481700 AR androgen receptor 2 2
MIRT482543 ACTB actin beta 2 4
MIRT482627 ABCE1 ATP binding cassette subfamily E member 1 2 2
MIRT484725 INHBA inhibin beta A subunit 2 12
MIRT487778 ANKEF1 ankyrin repeat and EF-hand domain containing 1 2 16
MIRT491883 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT494653 ARNTL aryl hydrocarbon receptor nuclear translocator like 2 2
MIRT497366 SF1 splicing factor 1 2 2
MIRT499156 HSPA1B heat shock protein family A (Hsp70) member 1B 2 8
MIRT502830 CELSR3 cadherin EGF LAG seven-pass G-type receptor 3 2 6
MIRT502944 CDC37L1 cell division cycle 37 like 1 2 8
MIRT503942 FBXL13 F-box and leucine rich repeat protein 13 2 4
MIRT504235 MYO6 myosin VI 2 2
MIRT504453 MC2R melanocortin 2 receptor 2 2
MIRT506022 PURA purine rich element binding protein A 2 2
MIRT508028 BCAT1 branched chain amino acid transaminase 1 2 4
MIRT508299 YES1 YES proto-oncogene 1, Src family tyrosine kinase 2 4
MIRT511515 HMGN2 high mobility group nucleosomal binding domain 2 2 2
MIRT512307 AMER1 APC membrane recruitment protein 1 2 6
MIRT514565 XRCC3 X-ray repair cross complementing 3 2 4
MIRT515657 MYBPC1 myosin binding protein C, slow type 2 2
MIRT518429 SSU72 SSU72 homolog, RNA polymerase II CTD phosphatase 2 2
MIRT520378 UBE2D1 ubiquitin conjugating enzyme E2 D1 2 4
MIRT521604 PSMA2 proteasome subunit alpha 2 2 4
MIRT521725 PPP3R1 protein phosphatase 3 regulatory subunit B, alpha 2 4
MIRT522579 MBNL3 muscleblind like splicing regulator 3 2 4
MIRT522731 LRRC55 leucine rich repeat containing 55 2 8
MIRT524547 CDC5L cell division cycle 5 like 2 4
MIRT525371 SYNM synemin 2 2
MIRT526489 PPIA peptidylprolyl isomerase A 2 4
MIRT527197 CLASP1 cytoplasmic linker associated protein 1 2 2
MIRT527285 FBLN2 fibulin 2 2 2
MIRT527383 MGARP mitochondria localized glutamic acid rich protein 2 2
MIRT527409 SMU1 DNA replication regulator and spliceosomal factor 2 6
MIRT527454 COL4A3 collagen type IV alpha 3 chain 2 2
MIRT528348 TBC1D22B TBC1 domain family member 22B 2 2
MIRT529104 ZNF100 zinc finger protein 100 2 2
MIRT529317 ATRNL1 attractin like 1 2 2
MIRT529328 PDE5A phosphodiesterase 5A 2 2
MIRT529750 SEL1L SEL1L ERAD E3 ligase adaptor subunit 2 2
MIRT530277 MKRN3 makorin ring finger protein 3 2 2
MIRT531415 TMEM18 transmembrane protein 18 2 2
MIRT532544 WDR13 WD repeat domain 13 2 2
MIRT533245 VKORC1L1 vitamin K epoxide reductase complex subunit 1 like 1 2 2
MIRT534659 RNF20 ring finger protein 20 2 2
MIRT534818 RAB33B RAB33B, member RAS oncogene family 2 2
MIRT537492 FAM169A family with sequence similarity 169 member A 2 2
MIRT538778 CABLES1 Cdk5 and Abl enzyme substrate 1 2 2
MIRT539122 ARL10 ADP ribosylation factor like GTPase 10 2 2
MIRT540964 SLC25A43 solute carrier family 25 member 43 2 2
MIRT541403 CDC27 cell division cycle 27 2 2
MIRT543353 ZNF829 zinc finger protein 829 2 2
MIRT543623 MFAP3 microfibril associated protein 3 2 2
MIRT543649 YY2 YY2 transcription factor 2 2
MIRT544945 SNCB synuclein beta 2 2
MIRT545327 SPC25 SPC25, NDC80 kinetochore complex component 2 2
MIRT546094 VEZF1 vascular endothelial zinc finger 1 2 2
MIRT548605 DCUN1D3 defective in cullin neddylation 1 domain containing 3 2 2
MIRT548638 DAZAP1 DAZ associated protein 1 2 4
MIRT550318 ZNF681 zinc finger protein 681 2 2
MIRT550412 SLC29A1 solute carrier family 29 member 1 (Augustine blood group) 2 4
MIRT551034 SPPL3 signal peptide peptidase like 3 2 2
MIRT551602 HDGFRP2 HDGF like 2 2 2
MIRT552064 ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 2 4
MIRT552803 YAF2 YY1 associated factor 2 2 2
MIRT553274 TVP23C trans-golgi network vesicle protein 23 homolog C 2 2
MIRT553303 TSPAN3 tetraspanin 3 2 2
MIRT553570 NPM3 nucleophosmin/nucleoplasmin 3 2 2
MIRT554844 RECK reversion inducing cysteine rich protein with kazal motifs 2 2
MIRT556069 MTF2 metal response element binding transcription factor 2 2 4
MIRT556898 ITGA2 integrin subunit alpha 2 2 2
MIRT558680 CNIH cornichon family AMPA receptor auxiliary protein 1 1 1
MIRT559032 C20orf24 chromosome 20 open reading frame 24 2 2
MIRT559108 C18orf25 chromosome 18 open reading frame 25 2 2
MIRT559864 GSKIP GSK3B interacting protein 2 2
MIRT560868 GAL3ST3 galactose-3-O-sulfotransferase 3 2 2
MIRT562268 GRB2 growth factor receptor bound protein 2 2 2
MIRT562419 EIF2S2 eukaryotic translation initiation factor 2 subunit beta 2 2
MIRT562652 ARID1A AT-rich interaction domain 1A 2 4
MIRT563771 ZNF678 zinc finger protein 678 2 2
MIRT564279 DEPDC1B DEP domain containing 1B 2 2
MIRT565253 TRA2B transformer 2 beta homolog 2 4
MIRT565307 TMEM64 transmembrane protein 64 2 2
MIRT566034 RFX1 regulatory factor X1 2 2
MIRT566714 MTMR3 myotubularin related protein 3 2 2
MIRT568087 CELF2 CUGBP Elav-like family member 2 2 2
MIRT568417 ATF7IP activating transcription factor 7 interacting protein 2 2
MIRT568766 MYBL1 MYB proto-oncogene like 1 2 2
MIRT569516 THYN1 thymocyte nuclear protein 1 2 2
MIRT571823 PHF19 PHD finger protein 19 2 2
MIRT571995 HOXA9 homeobox A9 2 2
MIRT572174 CELF1 CUGBP Elav-like family member 1 2 2
MIRT572637 ACOT9 acyl-CoA thioesterase 9 2 2
MIRT573756 KHSRP KH-type splicing regulatory protein 2 2
MIRT574089 CCDC132 VPS50, EARP/GARPII complex subunit 2 6
MIRT574311 CMTM6 CKLF like MARVEL transmembrane domain containing 6 2 2
MIRT574512 PSAT1 phosphoserine aminotransferase 1 2 2
MIRT574559 NRBF2 nuclear receptor binding factor 2 2 2
MIRT576686 H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 2 2
MIRT608491 NKTR natural killer cell triggering receptor 2 6
MIRT608640 ATP9A ATPase phospholipid transporting 9A (putative) 2 6
MIRT609231 TMEM189 transmembrane protein 189 2 2
MIRT609561 TCEAL4 transcription elongation factor A like 4 2 2
MIRT610193 FAM49A family with sequence similarity 49 member A 2 2
MIRT610681 SYT2 synaptotagmin 2 2 4
MIRT610725 NAV2 neuron navigator 2 2 2
MIRT610813 SGOL2 shugoshin 2 2 2
MIRT610993 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 2
MIRT611030 KCNK10 potassium two pore domain channel subfamily K member 10 2 2
MIRT611339 SLC2A4 solute carrier family 2 member 4 2 2
MIRT611511 HIPK3 homeodomain interacting protein kinase 3 2 2
MIRT611638 EDIL3 EGF like repeats and discoidin domains 3 2 2
MIRT611856 RPL3L ribosomal protein L3 like 2 2
MIRT611905 TRPC3 transient receptor potential cation channel subfamily C member 3 2 2
MIRT612047 PCNXL2 pecanex homolog 2 2 6
MIRT612340 TRIB2 tribbles pseudokinase 2 2 2
MIRT612870 INO80C INO80 complex subunit C 2 2
MIRT613555 AMPD3 adenosine monophosphate deaminase 3 2 2
MIRT614490 MMS22L MMS22 like, DNA repair protein 2 2
MIRT615098 BRD4 bromodomain containing 4 2 2
MIRT616228 PTPN11 protein tyrosine phosphatase, non-receptor type 11 2 2
MIRT617220 GDPGP1 GDP-D-glucose phosphorylase 1 2 2
MIRT617884 ESR1 estrogen receptor 1 2 2
MIRT618344 CD59 CD59 molecule (CD59 blood group) 2 2
MIRT620264 RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2 2
MIRT620660 CCDC108 cilia and flagella associated protein 65 2 2
MIRT620761 CCR5 C-C motif chemokine receptor 5 (gene/pseudogene) 2 2
MIRT621416 TXNL1 thioredoxin like 1 2 2
MIRT621676 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 2
MIRT622231 SLC25A51 solute carrier family 25 member 51 2 2
MIRT622377 SALL1 spalt like transcription factor 1 2 2
MIRT622404 RRAGC Ras related GTP binding C 2 2
MIRT622494 RC3H1 ring finger and CCCH-type domains 1 2 2
MIRT623064 NRXN1 neurexin 1 2 2
MIRT623295 MAX MYC associated factor X 2 2
MIRT623691 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT623930 FMNL3 formin like 3 2 2
MIRT623984 FAM208A family with sequence similarity 208 member A 2 2
MIRT624513 C7orf55-LUC7L2 C7orf55-LUC7L2 readthrough 2 2
MIRT624668 ARID4A AT-rich interaction domain 4A 2 2
MIRT624756 ANGPTL2 angiopoietin like 2 2 2
MIRT624949 MARCH2 membrane associated ring-CH-type finger 2 2 2
MIRT625968 RNF2 ring finger protein 2 2 2
MIRT626415 KIAA2018 upstream transcription factor family member 3 2 2
MIRT626882 AP3B1 adaptor related protein complex 3 beta 1 subunit 2 2
MIRT627157 ZNF652 zinc finger protein 652 2 2
MIRT627613 SFT2D2 SFT2 domain containing 2 2 2
MIRT627744 RAP2B RAP2B, member of RAS oncogene family 2 4
MIRT627808 PTEN phosphatase and tensin homolog 2 2
MIRT627820 PRR3 proline rich 3 2 2
MIRT630935 UNC93A unc-93 homolog A 2 2
MIRT635930 GLTSCR2 NOP53 ribosome biogenesis factor 2 2
MIRT638301 SERBP1 SERPINE1 mRNA binding protein 1 2 2
MIRT638437 PNRC1 proline rich nuclear receptor coactivator 1 2 2
MIRT640281 TCF24 transcription factor 24 2 2
MIRT641979 PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 2 2
MIRT644179 GIN1 gypsy retrotransposon integrase 1 2 2
MIRT644439 VDR vitamin D receptor 2 2
MIRT644974 STEAP4 STEAP4 metalloreductase 2 2
MIRT647653 B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 2 2
MIRT648702 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT650120 ZCCHC9 zinc finger CCHC-type containing 9 2 2
MIRT650505 UFM1 ubiquitin fold modifier 1 2 2
MIRT650701 CLNK cytokine dependent hematopoietic cell linker 2 2
MIRT651083 ZNF518B zinc finger protein 518B 2 4
MIRT653644 SLC30A1 solute carrier family 30 member 1 2 2
MIRT653788 SIX4 SIX homeobox 4 2 2
MIRT656773 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT656949 KIAA1456 KIAA1456 2 2
MIRT656981 KDM5A lysine demethylase 5A 2 2
MIRT657225 TOR1AIP2 torsin 1A interacting protein 2 2 4
MIRT657706 GPC5 glypican 5 2 2
MIRT660107 BTBD3 BTB domain containing 3 2 2
MIRT662817 C9orf64 chromosome 9 open reading frame 64 2 2
MIRT665889 TGIF2 TGFB induced factor homeobox 2 2 2
MIRT668140 GINS2 GINS complex subunit 2 2 2
MIRT668566 ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit 2 2
MIRT669718 AAGAB alpha and gamma adaptin binding protein 2 2
MIRT685693 TRIM45 tripartite motif containing 45 2 2
MIRT686579 TMPPE transmembrane protein with metallophosphoesterase domain 2 2
MIRT687491 NHLRC2 NHL repeat containing 2 2 2
MIRT687805 KCNJ15 potassium voltage-gated channel subfamily J member 15 2 2
MIRT687968 HHIP hedgehog interacting protein 2 2
MIRT689487 SCIMP SLP adaptor and CSK interacting membrane protein 2 2
MIRT689595 NUDT7 nudix hydrolase 7 2 2
MIRT690501 RSRC1 arginine and serine rich coiled-coil 1 2 2
MIRT692290 XRN2 5'-3' exoribonuclease 2 2 2
MIRT693060 KIAA1324 KIAA1324 2 2
MIRT697443 ZFHX3 zinc finger homeobox 3 2 2
MIRT698475 TJP1 tight junction protein 1 2 2
MIRT699033 SOAT1 sterol O-acyltransferase 1 2 2
MIRT699785 SEMA4D semaphorin 4D 2 2
MIRT701463 NEO1 neogenin 1 2 2
MIRT701869 MRO maestro 2 2
MIRT702158 MAP3K1 mitogen-activated protein kinase kinase kinase 1 2 2
MIRT703750 FAM126B family with sequence similarity 126 member B 2 2
MIRT704277 DGS2 DiGeorge syndrome/velocardiofacial syndrome complex 2 2 2
MIRT707956 PGM3 phosphoglucomutase 3 2 2
MIRT712747 LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 2 2
MIRT712848 RHOA ras homolog family member A 2 2
MIRT712954 CCBE1 collagen and calcium binding EGF domains 1 2 2
MIRT713119 U2SURP U2 snRNP associated SURP domain containing 2 2
MIRT713148 PKIA cAMP-dependent protein kinase inhibitor alpha 2 2
MIRT715394 TADA3 transcriptional adaptor 3 2 2
MIRT715475 NEGR1 neuronal growth regulator 1 2 2
MIRT715535 G2E3 G2/M-phase specific E3 ubiquitin protein ligase 2 2
MIRT721159 MYOCD myocardin 2 2
MIRT722719 ZNF460 zinc finger protein 460 2 2
MIRT723130 GTF2F2 general transcription factor IIF subunit 2 2 2
MIRT723259 TMLHE trimethyllysine hydroxylase, epsilon 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-54 Nicotine approved 89594 Microarray Caenorhabditis elegans 23765240 2013 up-regualted
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-548ac Cisplatin 5460033 NSC119875 approved sensitive cell line (BxPC3)
hsa-miR-548ac Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-548ac Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-548ac Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-548ac Paclitaxel 36314 NSC125973 approved sensitive cell line (HS578T)
hsa-miR-548ac Paclitaxel 36314 NSC125973 approved resistant cell line (BAS)
hsa-miR-548ac Doxorubicin 31703 NSC123127 approved resistant cell line (BAS)
hsa-miR-548ac Doxorubicin 31703 NSC123127 approved sensitive cell line (HS578T)
hsa-miR-548ac Tamoxifen+Fulvestrant resistant cell line (LCC9)
hsa-miR-548ac Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)

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