miRTarBase - #MIRT078056


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pre-miRNA Information
pre-miRNA hsa-mir-4282   
Genomic Coordinates chr6: 72967687 - 72967753
Description Homo sapiens miR-4282 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4282
Sequence 40| UAAAAUUUGCAUCCAGGA |57
Evidence Experimental
Experiments SOLiD
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN32074657 13 COSMIC
COSN6331413 18 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1195771339 5 dbSNP
rs755058572 6 dbSNP
rs1245753664 11 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol PCTP   
Synonyms PC-TP, STARD2
Description phosphatidylcholine transfer protein
Transcript NM_001102402   
Other Transcripts NM_021213   
Expression
Putative miRNA Targets on PCTP
3'UTR of PCTP
(miRNA target sites are highlighted)		 
>PCTP|NM_001102402|3'UTR
   1 GAAAGAGAACTGGGAACATTGCATCCATGGGTTGATGTCTCTGGAAGTGCAACCACCCAATGTCTCTGGAAGTGCCACCT
  81 GGAAGTGCCACCTGGAAGTGTCTCTGGAAGAGCACCCACCACTGTTCAGCCTTCCCCTGCTGTTTCTGTCTTCAGAGGCC
 161 TACACACTACCACATCCTTTCTAAGCATGTTTGCCTGACATCCAGCTCACTCGTCTGCTTCCTTTCTCGCTCCCCCCATC
 241 CTGGGCTGGGCTGCCTTCTTCTACAGTTCAATATGGGGCAGACTAGGGAAACCTTTGCTTGCTTACTATTAGGAGGGGAA
 321 GTCTTCAGTAGGGAACACGATCATTCCATTGTGCAATTTTACGGGGATGGGTGGGCGGAGGGACACAACAAAATTTAAGA
 401 ATGACTATTTGGGCGGGCTGGCTCTTTTGCAGCTTGTGATTTCTTCCAGCTTGGGAGGGGCTGCTGGAAGTGGCATTTCG
 481 TTCAGAGCTGACTTTCAGTGCACCCAAACTGGATGACGTGCCAATGTCCATTTGCCTTATGCTTTGTGGAGCTGATTAGG
 561 CTGGGATTTGAGGTGATAATCCAGTAAGTCTTTCCTCGTTCCTACTTGTGGAGGATCAGTAGCTGTTATGATGCCAGACC
 641 ATTTGGAGAAGTATCAGAGGCCTGACCGGACACATAATATGACAACCACATTTTTCCTCATCATCCATGAGGAAATGGAT
 721 GATTTCTCTTTTCCATATGTCACTGGGGGAAAGGCTGCCTGTACCTCTCAAGCTTTGCATTTTACTGGAAACTGAGGCGT
 801 CAAGATGGCTGTGGCAGCTAGCAAAAGCAAAGATGCTTTGTGCATAGCCTTGTGAAAAAGTATCTTTCTATGCAATAAGA
 881 TGAATTTTCCTCCCAGAATATTTAGAAATGTAGAAGGGATAACAGTTCACAGCCAGGTAAAATTTAACTGGTGGCTTAAT
 961 GACTCTGCACCTTTTTCTCAGGAATTCTGCCTAAGTTGTCTGCCTTTTCTACCACCAAAAAGACTTTTAGTTTTCTATGC
1041 TTTCTCCTGAATTTTGGTAGGGTAAGGTATTTCTATGTCAAAGGCACAGCCTTGATGATCTCAGGGAAAAATTTTAATCA
1121 CTGTGTATAATGATACTGAACCTTGATTAATAACAGAAATTCAGGATGTAAAGCCACAGAATGGGATTTATTAATGTGGG
1201 ATACCTCAGACTGTTTGTTTTCTTTCTGGGAAGAAAAGTGTGTTCTATAATGAATAAATATAGAGTGGTTTTTACTTGTC
1281 CTGTGTAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aggaCCUACGUUUAAAAu 5'
              |||   ||||||| 
Target 5' tcagGGA--AAAATTTTa 3'
 1101 - 1116 142.00 -8.30
2 
miRNA  3' aggaccuacGUUUAAAAu 5'
                   ::|||||| 
Target 5' gctttctccTGAATTTTg 3'
 1039 - 1056 125.00 -5.40
3 
miRNA  3' aggaccuacguUUAAAAu 5'
                     |||||| 
Target 5' ttccattgtgcAATTTTa 3'
 344 - 361 120.00 -7.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30113162 8 COSMIC
COSN21080838 23 COSMIC
COSN30484550 26 COSMIC
COSN20078906 60 COSMIC
COSN31511114 79 COSMIC
COSN30127286 126 COSMIC
COSN18837868 343 COSMIC
COSN32055747 741 COSMIC
COSN14583834 768 COSMIC
COSN32056169 823 COSMIC
COSN31547327 1023 COSMIC
COSN31487785 1133 COSMIC
COSN28813298 1267 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1192135567 3 dbSNP
rs1446653116 4 dbSNP
rs180894805 9 dbSNP
rs776312472 11 dbSNP
rs761400564 13 dbSNP
rs1423367723 20 dbSNP
rs764750613 21 dbSNP
rs1172728084 22 dbSNP
rs1360963554 23 dbSNP
rs185946193 26 dbSNP
rs758264699 28 dbSNP
rs766298248 29 dbSNP
rs1436655905 32 dbSNP
rs751553532 35 dbSNP
rs754492085 35 dbSNP
rs1178015626 36 dbSNP
rs1023084148 41 dbSNP
rs1276228788 47 dbSNP
rs754781005 51 dbSNP
rs780890795 52 dbSNP
rs1310365611 53 dbSNP
rs1244458324 56 dbSNP
rs1298088820 59 dbSNP
rs975500871 61 dbSNP
rs1242288069 66 dbSNP
rs568172020 66 dbSNP
rs1319145096 80 dbSNP
rs1284312662 101 dbSNP
rs970200539 104 dbSNP
rs1360716674 114 dbSNP
rs554754075 118 dbSNP
rs984743959 121 dbSNP
rs1242869030 123 dbSNP
rs1378507046 133 dbSNP
rs1289711229 137 dbSNP
rs913154615 139 dbSNP
rs945916986 158 dbSNP
rs981290660 164 dbSNP
rs772460708 166 dbSNP
rs1425227181 168 dbSNP
rs750136093 169 dbSNP
rs928476300 170 dbSNP
rs1161155496 175 dbSNP
rs1422776417 180 dbSNP
rs1187963199 183 dbSNP
rs1261773081 183 dbSNP
rs1285250344 185 dbSNP
rs1484679436 186 dbSNP
rs555601609 189 dbSNP
rs76126995 211 dbSNP
rs1487246249 213 dbSNP
rs780693107 214 dbSNP
rs572776258 216 dbSNP
rs937150622 227 dbSNP
rs1261738876 229 dbSNP
rs971737511 230 dbSNP
rs1321267478 232 dbSNP
rs1422937031 233 dbSNP
rs1184953956 234 dbSNP
rs1055588041 236 dbSNP
rs918954949 237 dbSNP
rs533587297 238 dbSNP
rs887380260 239 dbSNP
rs1051551038 251 dbSNP
rs747635553 254 dbSNP
rs1422411561 255 dbSNP
rs888913243 257 dbSNP
rs535396131 262 dbSNP
rs943225682 265 dbSNP
rs1402739323 269 dbSNP
rs769398310 270 dbSNP
rs900042571 272 dbSNP
rs1421983734 275 dbSNP
rs1251972456 292 dbSNP
rs1043337965 298 dbSNP
rs556731066 300 dbSNP
rs1032428514 307 dbSNP
rs1277856718 309 dbSNP
rs1224319663 315 dbSNP
rs558540706 319 dbSNP
rs1401581571 320 dbSNP
rs1298900987 322 dbSNP
rs1386150942 323 dbSNP
rs999204513 330 dbSNP
rs1031622707 335 dbSNP
rs577440833 339 dbSNP
rs1460073653 350 dbSNP
rs1394553532 357 dbSNP
rs1336378265 358 dbSNP
rs1383739163 361 dbSNP
rs1481205963 363 dbSNP
rs1246483304 364 dbSNP
rs1197121910 370 dbSNP
rs1308175070 374 dbSNP
rs117573973 377 dbSNP
rs1020942954 378 dbSNP
rs1241080236 385 dbSNP
rs1023011992 388 dbSNP
rs1257495734 390 dbSNP
rs1260874331 394 dbSNP
rs1325853252 402 dbSNP
rs981386043 408 dbSNP
rs1198418950 412 dbSNP
rs562701483 415 dbSNP
rs762715351 416 dbSNP
rs770774590 419 dbSNP
rs1470755890 421 dbSNP
rs1403394709 425 dbSNP
rs1171211218 435 dbSNP
rs189666902 444 dbSNP
rs919701398 445 dbSNP
rs147250048 450 dbSNP
rs1438364306 452 dbSNP
rs1160434646 456 dbSNP
rs973429053 457 dbSNP
rs1377190848 458 dbSNP
rs1464629162 465 dbSNP
rs918923914 469 dbSNP
rs954364269 473 dbSNP
rs987185503 480 dbSNP
rs774154879 481 dbSNP
rs1262258512 503 dbSNP
rs943701324 512 dbSNP
rs1352812685 518 dbSNP
rs1446248903 519 dbSNP
rs796068019 524 dbSNP
rs1338166395 525 dbSNP
rs1333142878 526 dbSNP
rs1382431472 527 dbSNP
rs1386200704 529 dbSNP
rs1374374996 531 dbSNP
rs943175258 533 dbSNP
rs1418409081 540 dbSNP
rs1393107244 544 dbSNP
rs181213847 558 dbSNP
rs767371362 563 dbSNP
rs1366797696 569 dbSNP
rs934590012 583 dbSNP
rs1052966801 584 dbSNP
rs1187181034 585 dbSNP
rs185994947 593 dbSNP
rs1032893629 596 dbSNP
rs552252949 598 dbSNP
rs1044433663 599 dbSNP
rs564510346 605 dbSNP
rs1248037678 612 dbSNP
rs1353727474 626 dbSNP
rs1283070385 630 dbSNP
rs777757590 632 dbSNP
rs905928055 639 dbSNP
rs1327757853 642 dbSNP
rs1006077869 646 dbSNP
rs1267307147 664 dbSNP
rs1017094645 668 dbSNP
rs1035616260 669 dbSNP
rs1178698009 675 dbSNP
rs2303506 681 dbSNP
rs994391538 682 dbSNP
rs1029928998 691 dbSNP
rs10445322 698 dbSNP
rs1465360751 707 dbSNP
rs760875258 708 dbSNP
rs1162670589 712 dbSNP
rs919779720 720 dbSNP
rs954333212 720 dbSNP
rs1352595604 729 dbSNP
rs987154388 734 dbSNP
rs1463349093 736 dbSNP
rs557361200 738 dbSNP
rs1477395361 739 dbSNP
rs952565497 740 dbSNP
rs764385191 743 dbSNP
rs982531876 750 dbSNP
rs908294713 752 dbSNP
rs1195826069 755 dbSNP
rs779453808 758 dbSNP
rs1275958309 759 dbSNP
rs964482126 762 dbSNP
rs1217632588 766 dbSNP
rs1384944796 770 dbSNP
rs943707710 779 dbSNP
rs754167190 784 dbSNP
rs1439225960 786 dbSNP
rs190453563 791 dbSNP
rs1040652667 792 dbSNP
rs539781889 799 dbSNP
rs921530561 800 dbSNP
rs925767090 814 dbSNP
rs1168882886 820 dbSNP
rs1465285596 821 dbSNP
rs1429748828 829 dbSNP
rs934495380 831 dbSNP
rs9894355 840 dbSNP
rs1477016261 849 dbSNP
rs1246003718 853 dbSNP
rs183437034 860 dbSNP
rs1054021839 865 dbSNP
rs1205667694 871 dbSNP
rs536478557 872 dbSNP
rs1197644651 879 dbSNP
rs1323719612 887 dbSNP
rs917189605 905 dbSNP
rs1265171055 907 dbSNP
rs1487826204 913 dbSNP
rs1221247583 916 dbSNP
rs1365904407 918 dbSNP
rs893993982 920 dbSNP
rs779270040 924 dbSNP
rs1379283729 932 dbSNP
rs11556499 933 dbSNP
rs1044347589 934 dbSNP
rs1269741547 937 dbSNP
rs905867270 940 dbSNP
rs1477524277 953 dbSNP
rs1191534843 954 dbSNP
rs1421951315 963 dbSNP
rs548252826 967 dbSNP
rs1177990033 969 dbSNP
rs13477 971 dbSNP
rs750764787 992 dbSNP
rs140981103 1003 dbSNP
rs1424203300 1008 dbSNP
rs906582106 1019 dbSNP
rs1441408189 1023 dbSNP
rs1003558596 1024 dbSNP
rs1177425699 1024 dbSNP
rs1461509108 1025 dbSNP
rs1038900055 1028 dbSNP
rs1207551330 1033 dbSNP
rs1170892224 1036 dbSNP
rs780457644 1041 dbSNP
rs1033657263 1054 dbSNP
rs1278344424 1066 dbSNP
rs1224839764 1075 dbSNP
rs897313610 1076 dbSNP
rs994366090 1077 dbSNP
rs1422716982 1092 dbSNP
rs1383583571 1094 dbSNP
rs931385704 1102 dbSNP
rs1366066016 1118 dbSNP
rs1446078312 1126 dbSNP
rs1358380772 1131 dbSNP
rs1398886325 1134 dbSNP
rs747628611 1137 dbSNP
rs769343182 1143 dbSNP
rs1378352901 1149 dbSNP
rs1157953719 1155 dbSNP
rs1363656157 1163 dbSNP
rs142459599 1167 dbSNP
rs1179814608 1169 dbSNP
rs952694888 1178 dbSNP
rs1237269154 1182 dbSNP
rs1217748383 1185 dbSNP
rs1007160308 1187 dbSNP
rs1312543049 1187 dbSNP
rs1240014340 1190 dbSNP
rs1322468651 1197 dbSNP
rs1314874082 1202 dbSNP
rs186256815 1212 dbSNP
rs908305613 1212 dbSNP
rs1270575464 1234 dbSNP
rs1225429312 1236 dbSNP
rs1293167074 1239 dbSNP
rs1358358627 1243 dbSNP
rs576438545 1246 dbSNP
rs1214544058 1251 dbSNP
rs1243857455 1259 dbSNP
rs115562564 1261 dbSNP
rs1033207091 1263 dbSNP
rs1181468382 1264 dbSNP
rs192160159 1266 dbSNP
rs1422912445 1269 dbSNP
rs1419725532 1270 dbSNP
rs770578511 1275 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 58488.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aggaCCUACGUUUAAAAu 5'
              |||   ||||||| 
Target 5' ucagGGA--AAAAUUUUa 3'
 		4 - 19
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM4903825
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / PID14_NS
Location of target site NM_001102402 | 3UTR | AGCCUUGAUGAUCUCAGGGAAAAAUUUUAAUCACUGUGUAUAAUGAUACUGAACCUUGAUUAAUAACAGAAAUUCAGGAUGUAAAGCCACAGAAUGGGAUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161237
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000576183.1 | 3UTR | AUCUCAGGGAAAAAUUUUAAUCACUGUGUAUAAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
280 hsa-miR-4282 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT057628 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT060732 RPS3 ribosomal protein S3 2 2
MIRT063371 ETNK1 ethanolamine kinase 1 2 2
MIRT066257 LRIG3 leucine rich repeats and immunoglobulin like domains 3 2 4
MIRT070774 HIF1A hypoxia inducible factor 1 alpha subunit 2 2
MIRT070871 EIF2S1 eukaryotic translation initiation factor 2 subunit alpha 2 4
MIRT078056 PCTP phosphatidylcholine transfer protein 2 2
MIRT078408 DCAF7 DDB1 and CUL4 associated factor 7 2 4
MIRT084059 PPP1R3D protein phosphatase 1 regulatory subunit 3D 2 2
MIRT093537 GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 2 6
MIRT096072 SFXN1 sideroflexin 1 2 2
MIRT098316 REV3L REV3 like, DNA directed polymerase zeta catalytic subunit 2 2
MIRT100493 UHRF1BP1 UHRF1 binding protein 1 2 2
MIRT102254 HBP1 HMG-box transcription factor 1 2 4
MIRT105318 VPS37A VPS37A, ESCRT-I subunit 2 2
MIRT114143 MZT1 mitotic spindle organizing protein 1 2 4
MIRT114873 DICER1 dicer 1, ribonuclease III 2 2
MIRT134683 PNRC2 proline rich nuclear receptor coactivator 2 2 2
MIRT137640 RCOR1 REST corepressor 1 2 2
MIRT155449 CCNT2 cyclin T2 2 4
MIRT165656 DCTN4 dynactin subunit 4 2 2
MIRT177570 CSTF2T cleavage stimulation factor subunit 2 tau variant 2 4
MIRT188514 E2F7 E2F transcription factor 7 2 10
MIRT193019 TMOD3 tropomodulin 3 2 4
MIRT195823 GADD45A growth arrest and DNA damage inducible alpha 2 2
MIRT195885 DEPDC1 DEP domain containing 1 2 6
MIRT206029 NUP50 nucleoporin 50 2 6
MIRT212148 CLCN3 chloride voltage-gated channel 3 2 2
MIRT213999 DCP2 decapping mRNA 2 2 2
MIRT214650 HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 2 2
MIRT221568 CBX3 chromobox 3 2 2
MIRT224544 ZNF623 zinc finger protein 623 2 2
MIRT227654 SET SET nuclear proto-oncogene 2 2
MIRT229992 CHIC1 cysteine rich hydrophobic domain 1 2 2
MIRT238968 QKI QKI, KH domain containing RNA binding 2 2
MIRT239825 ACTB actin beta 2 2
MIRT241084 ZXDA zinc finger, X-linked, duplicated A 2 4
MIRT244852 ZBTB5 zinc finger and BTB domain containing 5 2 2
MIRT264534 TARDBP TAR DNA binding protein 2 2
MIRT271438 SKI SKI proto-oncogene 2 2
MIRT271597 ENAH ENAH, actin regulator 2 2
MIRT294332 ZNF264 zinc finger protein 264 2 2
MIRT296341 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT301715 TEF TEF, PAR bZIP transcription factor 2 2
MIRT308549 ZNF654 zinc finger protein 654 2 2
MIRT313866 DEPDC1B DEP domain containing 1B 2 2
MIRT315529 MARCKS myristoylated alanine rich protein kinase C substrate 2 2
MIRT321066 RABGEF1 RAB guanine nucleotide exchange factor 1 2 2
MIRT343777 NUTF2 nuclear transport factor 2 2 2
MIRT359109 MAP1B microtubule associated protein 1B 2 2
MIRT397393 GOLGA3 golgin A3 2 4
MIRT400822 CPEB2 cytoplasmic polyadenylation element binding protein 2 2 2
MIRT442171 DSEL dermatan sulfate epimerase-like 2 2
MIRT442777 JAG1 jagged 1 2 2
MIRT442862 SCARF1 scavenger receptor class F member 1 2 4
MIRT442919 PCBD2 pterin-4 alpha-carbinolamine dehydratase 2 2 2
MIRT444567 TRA2B transformer 2 beta homolog 2 2
MIRT444718 CMSS1 cms1 ribosomal small subunit homolog (yeast) 2 2
MIRT445018 RBMS3 RNA binding motif single stranded interacting protein 3 2 2
MIRT445853 LRRC1 leucine rich repeat containing 1 2 2
MIRT446242 HELZ helicase with zinc finger 2 2
MIRT446542 GOLGA8B golgin A8 family member B 2 2
MIRT446643 SPTY2D1 SPT2 chromatin protein domain containing 1 2 2
MIRT446948 ZMAT3 zinc finger matrin-type 3 2 4
MIRT447061 KCNAB1 potassium voltage-gated channel subfamily A member regulatory beta subunit 1 2 2
MIRT447327 ZSCAN21 zinc finger and SCAN domain containing 21 2 2
MIRT447995 CDX1 caudal type homeobox 1 2 2
MIRT448543 RHEBP1 RHEB pseudogene 1 2 6
MIRT448752 HINT1 histidine triad nucleotide binding protein 1 2 2
MIRT448772 GOLGA8A golgin A8 family member A 2 2
MIRT449342 WDR26 WD repeat domain 26 2 2
MIRT450011 SLC16A6 solute carrier family 16 member 6 2 4
MIRT450229 PCNX pecanex homolog 1 2 2
MIRT450340 MRPL17 mitochondrial ribosomal protein L17 2 4
MIRT450381 MSI2 musashi RNA binding protein 2 2 2
MIRT450759 PGGT1B protein geranylgeranyltransferase type I subunit beta 2 2
MIRT450809 NRCAM neuronal cell adhesion molecule 2 2
MIRT450947 ATAD2 ATPase family, AAA domain containing 2 2 2
MIRT459095 CCPG1 cell cycle progression 1 2 2
MIRT462428 TWISTNB TWIST neighbor 2 2
MIRT465200 TROVE2 TROVE domain family member 2 2 4
MIRT467382 SON SON DNA binding protein 2 4
MIRT468546 SERP1 stress associated endoplasmic reticulum protein 1 2 2
MIRT471506 PDE4D phosphodiesterase 4D 2 2
MIRT471981 NR3C1 nuclear receptor subfamily 3 group C member 1 2 2
MIRT474478 KLHL11 kelch like family member 11 2 8
MIRT475011 KANSL1 KAT8 regulatory NSL complex subunit 1 2 8
MIRT480341 C5orf51 chromosome 5 open reading frame 51 2 2
MIRT482696 TEX9 testis expressed 9 2 6
MIRT483462 YTHDF1 YTH N6-methyladenosine RNA binding protein 1 2 6
MIRT485623 FAM217B family with sequence similarity 217 member B 2 2
MIRT485714 CASP16 caspase 16, pseudogene 2 8
MIRT486279 SEC23A Sec23 homolog A, coat complex II component 2 2
MIRT491000 PEBP1 phosphatidylethanolamine binding protein 1 2 4
MIRT492594 PPIL4 peptidylprolyl isomerase like 4 2 2
MIRT493365 KIF5B kinesin family member 5B 2 2
MIRT494316 CDKN1B cyclin dependent kinase inhibitor 1B 2 2
MIRT495208 EDN3 endothelin 3 2 2
MIRT497011 TCF15 transcription factor 15 2 2
MIRT498512 FRK fyn related Src family tyrosine kinase 2 2
MIRT498778 PARP15 poly(ADP-ribose) polymerase family member 15 2 2
MIRT501045 SMG1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 2 6
MIRT502939 CDC37L1 cell division cycle 37 like 1 2 8
MIRT504806 VHL von Hippel-Lindau tumor suppressor 2 6
MIRT505656 SHMT1 serine hydroxymethyltransferase 1 2 6
MIRT505964 RAB5C RAB5C, member RAS oncogene family 2 6
MIRT506322 OTUD4 OTU deubiquitinase 4 2 4
MIRT506803 KLHL15 kelch like family member 15 2 6
MIRT506917 KBTBD8 kelch repeat and BTB domain containing 8 2 4
MIRT507400 EMC7 ER membrane protein complex subunit 7 2 8
MIRT507471 EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 2 6
MIRT508058 ATP13A3 ATPase 13A3 2 4
MIRT508135 AMD1 adenosylmethionine decarboxylase 1 2 2
MIRT509895 RPS23 ribosomal protein S23 2 4
MIRT510881 RAN RAN, member RAS oncogene family 2 8
MIRT513766 PEX5L peroxisomal biogenesis factor 5 like 2 4
MIRT516898 COPS8 COP9 signalosome subunit 8 2 2
MIRT518703 TIMD4 T-cell immunoglobulin and mucin domain containing 4 2 4
MIRT520429 TTPAL alpha tocopherol transfer protein like 2 6
MIRT521843 PNISR PNN interacting serine and arginine rich protein 2 4
MIRT522116 NUDT3 nudix hydrolase 3 2 4
MIRT525467 TMPRSS12 transmembrane protease, serine 12 2 2
MIRT525583 MTRNR2L7 MT-RNR2-like 7 2 2
MIRT525906 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 2 2
MIRT526072 C11orf54 chromosome 11 open reading frame 54 2 2
MIRT526232 MTRNR2L5 MT-RNR2-like 5 2 4
MIRT526455 FAM71F2 family with sequence similarity 71 member F2 2 4
MIRT526515 POU5F1B POU class 5 homeobox 1B 2 2
MIRT528032 FEZ2 fasciculation and elongation protein zeta 2 2 2
MIRT528422 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT528995 ISLR2 immunoglobulin superfamily containing leucine rich repeat 2 2 4
MIRT529311 ATRNL1 attractin like 1 2 2
MIRT529376 SKP1 S-phase kinase associated protein 1 2 4
MIRT530015 SRRM1 serine and arginine repetitive matrix 1 2 2
MIRT530089 FMN2 formin 2 2 2
MIRT530942 ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 2 2
MIRT531229 HIST1H2BD histone cluster 1 H2B family member d 2 2
MIRT533088 YTHDF3 YTH N6-methyladenosine RNA binding protein 3 2 2
MIRT533299 USP46 ubiquitin specific peptidase 46 2 2
MIRT533318 UNKL unkempt family like zinc finger 2 2
MIRT533721 TMEM30A transmembrane protein 30A 2 2
MIRT534096 AZF1 azoospermia factor 1 2 2
MIRT534188 SLC7A11 solute carrier family 7 member 11 2 2
MIRT534493 SAR1B secretion associated Ras related GTPase 1B 2 2
MIRT536077 MBOAT2 membrane bound O-acyltransferase domain containing 2 2 2
MIRT536242 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 2
MIRT537524 FAM104A family with sequence similarity 104 member A 2 2
MIRT538088 DGKH diacylglycerol kinase eta 2 2
MIRT538475 CNBP CCHC-type zinc finger nucleic acid binding protein 2 2
MIRT538853 BTG1 BTG anti-proliferation factor 1 2 4
MIRT539075 GDNF glial cell derived neurotrophic factor 2 2
MIRT539480 ACVR2B activin A receptor type 2B 2 4
MIRT540210 ARHGAP18 Rho GTPase activating protein 18 2 2
MIRT541940 TSPAN2 tetraspanin 2 2 2
MIRT543812 COCH cochlin 2 2
MIRT545120 PDZRN4 PDZ domain containing ring finger 4 2 2
MIRT545571 GIMAP4 GTPase, IMAP family member 4 2 2
MIRT545989 XKR4 XK related 4 2 2
MIRT547213 PANK3 pantothenate kinase 3 2 4
MIRT547740 KIAA1468 KIAA1468 2 2
MIRT548022 GRB2 growth factor receptor bound protein 2 2 4
MIRT548032 GOLIM4 golgi integral membrane protein 4 2 2
MIRT548102 GFPT1 glutamine--fructose-6-phosphate transaminase 1 2 4
MIRT548217 FKBP1A FK506 binding protein 1A 2 2
MIRT548588 DDX3X DEAD-box helicase 3, X-linked 2 4
MIRT548953 CDC27 cell division cycle 27 2 2
MIRT549072 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT550368 INCENP inner centromere protein 2 6
MIRT550546 MYZAP myocardial zonula adherens protein 2 2
MIRT551491 TMEM192 transmembrane protein 192 2 4
MIRT553078 UEVLD UEV and lactate/malate dehyrogenase domains 2 2
MIRT554104 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT555127 PTPRG protein tyrosine phosphatase, receptor type G 2 2
MIRT555477 POC1B-GALNT4 POC1B-GALNT4 readthrough 2 2
MIRT555978 NPTN neuroplastin 2 2
MIRT557011 HPRT1 hypoxanthine phosphoribosyltransferase 1 2 2
MIRT557706 GALNT4 polypeptide N-acetylgalactosaminyltransferase 4 2 2
MIRT558333 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 4
MIRT558488 DBN1 drebrin 1 2 2
MIRT559942 ZNF567 zinc finger protein 567 2 2
MIRT561127 ATP2B1 ATPase plasma membrane Ca2+ transporting 1 2 2
MIRT561791 PAWR pro-apoptotic WT1 regulator 2 2
MIRT562438 EEF2 eukaryotic translation elongation factor 2 2 2
MIRT563102 PABPC4L poly(A) binding protein cytoplasmic 4 like 2 2
MIRT563212 ZNF813 zinc finger protein 813 2 2
MIRT563426 KIF3A kinesin family member 3A 2 2
MIRT563473 SPIN4 spindlin family member 4 2 2
MIRT564015 HSPA4 heat shock protein family A (Hsp70) member 4 2 4
MIRT564117 ZYG11B zyg-11 family member B, cell cycle regulator 2 2
MIRT564223 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT564503 CACNG1 calcium voltage-gated channel auxiliary subunit gamma 1 2 2
MIRT564515 DUSP3 dual specificity phosphatase 3 2 2
MIRT564811 ZBTB21 zinc finger and BTB domain containing 21 2 2
MIRT565265 TPD52 tumor protein D52 2 2
MIRT566012 RHOB ras homolog family member B 2 2
MIRT566216 PTMA prothymosin, alpha 2 2
MIRT566638 NFYA nuclear transcription factor Y subunit alpha 2 2
MIRT566821 MAPK8 mitogen-activated protein kinase 8 2 2
MIRT566948 LEPROT leptin receptor overlapping transcript 2 2
MIRT567290 HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 2 2
MIRT567895 CSTF2 cleavage stimulation factor subunit 2 2 2
MIRT568731 MTRNR2L3 MT-RNR2-like 3 2 2
MIRT571263 ZNF239 zinc finger protein 239 2 2
MIRT572593 EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 2 2
MIRT573827 TGOLN2 trans-golgi network protein 2 2 2
MIRT576391 Fhl2 four and a half LIM domains 2 2 2
MIRT609901 SMS spermine synthase 2 2
MIRT613710 ELMSAN1 ELM2 and Myb/SANT domain containing 1 2 2
MIRT614406 ADAT1 adenosine deaminase, tRNA specific 1 2 2
MIRT615042 DCX doublecortin 2 2
MIRT617514 C5orf45 MRN complex interacting protein 2 2
MIRT619476 PRDM10 PR/SET domain 10 2 2
MIRT620349 TLN1 talin 1 2 2
MIRT620910 PLA2G7 phospholipase A2 group VII 2 2
MIRT622131 SP4 Sp4 transcription factor 2 2
MIRT622955 OTUD7B OTU deubiquitinase 7B 2 2
MIRT623351 MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 2 2
MIRT623619 INTU inturned planar cell polarity protein 2 2
MIRT624409 CCDC171 coiled-coil domain containing 171 2 2
MIRT625171 CCS copper chaperone for superoxide dismutase 2 2
MIRT625685 RPP40 ribonuclease P/MRP subunit p40 2 2
MIRT625875 ALDH18A1 aldehyde dehydrogenase 18 family member A1 2 2
MIRT626002 FAM107A family with sequence similarity 107 member A 2 2
MIRT626872 HRH4 histamine receptor H4 2 4
MIRT628220 FKBP9 FK506 binding protein 9 2 2
MIRT628265 DIO2 iodothyronine deiodinase 2 2 2
MIRT628402 C8orf37 chromosome 8 open reading frame 37 2 2
MIRT630564 C3orf36 chromosome 3 open reading frame 36 2 4
MIRT631577 RASSF9 Ras association domain family member 9 2 2
MIRT635730 CCDC58 coiled-coil domain containing 58 2 2
MIRT636224 SLC8A1 solute carrier family 8 member A1 2 2
MIRT636613 CLIC5 chloride intracellular channel 5 2 2
MIRT638899 CDK9 cyclin dependent kinase 9 2 2
MIRT640167 ATXN7L1 ataxin 7 like 1 2 2
MIRT642070 GTDC1 glycosyltransferase like domain containing 1 2 2
MIRT643034 CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 2 2
MIRT644572 SPOP speckle type BTB/POZ protein 2 2
MIRT644954 IFNB1 interferon beta 1 2 2
MIRT645948 TTF2 transcription termination factor 2 2 2
MIRT646440 XRCC2 X-ray repair cross complementing 2 2 2
MIRT647896 EPN2 epsin 2 2 2
MIRT648276 ZNF582 zinc finger protein 582 2 2
MIRT649381 NEDD1 neural precursor cell expressed, developmentally down-regulated 1 2 2
MIRT650254 CD68 CD68 molecule 2 2
MIRT650333 ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B) 2 2
MIRT651707 VMP1 vacuole membrane protein 1 2 2
MIRT651774 VASP vasodilator stimulated phosphoprotein 2 2
MIRT653144 SRPK2 SRSF protein kinase 2 2 2
MIRT654112 RPS6KA5 ribosomal protein S6 kinase A5 2 2
MIRT654161 RORB RAR related orphan receptor B 2 2
MIRT655716 MLF2 myeloid leukemia factor 2 2 2
MIRT657476 HDAC4 histone deacetylase 4 2 2
MIRT658095 FOXO1 forkhead box O1 2 2
MIRT658860 DTX3L deltex E3 ubiquitin ligase 3L 2 2
MIRT658988 DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 2 2
MIRT660767 ALDH6A1 aldehyde dehydrogenase 6 family member A1 2 2
MIRT661622 C2orf15 chromosome 2 open reading frame 15 2 2
MIRT661694 TFDP2 transcription factor Dp-2 2 2
MIRT662208 PLA2G4E phospholipase A2 group IVE 2 2
MIRT662443 RALGAPA1 Ral GTPase activating protein catalytic alpha subunit 1 2 2
MIRT664422 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2 2
MIRT687505 NECAB1 N-terminal EF-hand calcium binding protein 1 2 2
MIRT689910 SOD2 superoxide dismutase 2 2 2
MIRT690781 PLA2G2C phospholipase A2 group IIC 2 2
MIRT698488 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT699685 SFMBT2 Scm like with four mbt domains 2 2 2
MIRT700926 PDS5A PDS5 cohesin associated factor A 2 2
MIRT702258 LMNB1 lamin B1 2 2
MIRT703166 GPR137C G protein-coupled receptor 137C 2 2
MIRT703242 GNS glucosamine (N-acetyl)-6-sulfatase 2 2
MIRT704737 CENPQ centromere protein Q 2 2
MIRT707310 GLRX2 glutaredoxin 2 2 2
MIRT710021 KCNQ5 potassium voltage-gated channel subfamily Q member 5 2 2
MIRT712212 SCOC short coiled-coil protein 2 2
MIRT714742 SETBP1 SET binding protein 1 2 2
MIRT718268 ZNF749 zinc finger protein 749 2 2
MIRT720553 DYRK4 dual specificity tyrosine phosphorylation regulated kinase 4 2 2
MIRT722248 RBM41 RNA binding motif protein 41 2 2
MIRT723767 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT723977 KIAA0146 scaffolding protein involved in DNA repair 1 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4282 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4282 Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-4282 Neoadjuvant chemotherapy sensitive tissue (breast cancer)

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