miRTarBase - #MIRT082563


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pre-miRNA Information
pre-miRNA hsa-mir-5698   
Genomic Coordinates chr1: 154104521 - 154104592
Description Homo sapiens miR-5698 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-5698
Sequence 10| UGGGGGAGUGCAGUGAUUGUGG |31
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1341599256 3 dbSNP
rs1402386528 4 dbSNP
rs971952135 5 dbSNP
rs1391145061 7 dbSNP
rs1164729549 10 dbSNP
rs1456596412 17 dbSNP
rs1020488975 19 dbSNP
rs1219915431 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SLC1A5   
Synonyms AAAT, ASCT2, ATBO, M7V1, M7VS1, R16, RDRC
Description solute carrier family 1 member 5
Transcript NM_001145144   
Other Transcripts NM_001145145 , NM_005628   
Expression
Putative miRNA Targets on SLC1A5
3'UTR of SLC1A5
(miRNA target sites are highlighted)		 
>SLC1A5|NM_001145144|3'UTR
   1 ACCCCGGGAGGGACCTTCCCTGCCCTGCTGGGGGTGCTCTTTGGACACTGGATTATGAGGAATGGATAAATGGATGAGCT
  81 AGGGCTCTGGGGGTCTGCCTGCACACTCTGGGGAGCCAGGGGCCCCAGCACCCTCCAGGACAGGAGATCTGGGATGCCTG
 161 GCTGCTGGAGTACATGTGTTCACAAGGGTTACTCCTCAAAACCCCCAGTTCTCACTCATGTCCCCAACTCAAGGCTAGAA
 241 AACAGCAAGATGGAGAAATAATGTTCTGCTGCGTCCCCACCGTGACCTGCCTGGCCTCCCCTGTCTCAGGGAGCAGGTCA
 321 CAGGTCACCATGGGGAATTCTAGCCCCCACTGGGGGGATGTTACAACACCATGCTGGTTATTTTGGCGGCTGTAGTTGTG
 401 GGGGGATGTGTGTGTGCACGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTCTGTGACCTCCTGTCCCCATGG
 481 TACGTCCCACCCTGTCCCCAGATCCCCTATTCCCTCCACAATAACAGAAACACTCCCAGGGACTCTGGGGAGAGGCTGAG
 561 GACAAATACCTGCTGTCACTCCAGAGGACATTTTTTTTAGCAATAAAATTGAGTGTCAACTATTTAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ggUGUUAGU-GACG----UGAGGGGGu 5'
            || :| | ||||     ||||||: 
Target 5' ccACCGTGACCTGCCTGGCCTCCCCTg 3'
 277 - 303 134.00 -19.80
2 
miRNA  3' ggUGUUAGUGAC---GUGAGGGggu 5'
            ||||| || |   |||||||   
Target 5' ccACAATAACAGAAACACTCCCagg 3'
 516 - 540 132.00 -19.72
3 
miRNA  3' ggUGUUAGUGACGUGAGGGGgu 5'
            ||||  ::|  |||||:|  
Target 5' tcACAAGGGTT--ACTCCTCaa 3'
 180 - 199 120.00 -15.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30139477 2 COSMIC
COSN30717183 5 COSMIC
COSN31600850 6 COSMIC
COSN30525265 19 COSMIC
COSN31493057 20 COSMIC
COSN30513356 29 COSMIC
COSN30130209 69 COSMIC
COSN30464003 91 COSMIC
COSN31510557 99 COSMIC
COSN30502969 106 COSMIC
COSN30181003 135 COSMIC
COSN22476874 211 COSMIC
COSN6145609 356 COSMIC
COSN23527959 388 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1294270631 2 dbSNP
rs1382253740 3 dbSNP
rs774538305 4 dbSNP
rs529969003 5 dbSNP
rs749445334 6 dbSNP
rs1405868357 8 dbSNP
rs1177559354 9 dbSNP
rs1471094395 10 dbSNP
rs773479751 11 dbSNP
rs1372044580 12 dbSNP
rs769987963 14 dbSNP
rs1429127279 15 dbSNP
rs748169342 18 dbSNP
rs1397426234 22 dbSNP
rs1367372212 23 dbSNP
rs1012474872 25 dbSNP
rs895261202 28 dbSNP
rs1460801031 30 dbSNP
rs1048948513 31 dbSNP
rs780156575 32 dbSNP
rs1337066298 33 dbSNP
rs377465288 34 dbSNP
rs771858328 40 dbSNP
rs1384165667 45 dbSNP
rs745711019 46 dbSNP
rs1319192502 47 dbSNP
rs778544872 48 dbSNP
rs560908326 54 dbSNP
rs897170954 57 dbSNP
rs62134839 59 dbSNP
rs944312611 65 dbSNP
rs1276610846 69 dbSNP
rs1348506399 72 dbSNP
rs912790304 79 dbSNP
rs1233417286 94 dbSNP
rs1414005292 96 dbSNP
rs1489132785 101 dbSNP
rs1205409320 106 dbSNP
rs1353329925 120 dbSNP
rs1260596553 123 dbSNP
rs1314703519 129 dbSNP
rs1444848827 135 dbSNP
rs1448645914 147 dbSNP
rs371673136 160 dbSNP
rs1253018308 164 dbSNP
rs901214366 170 dbSNP
rs932806897 177 dbSNP
rs1408434968 181 dbSNP
rs1041437498 186 dbSNP
rs921744848 190 dbSNP
rs1475108240 207 dbSNP
rs564639315 215 dbSNP
rs1380674556 219 dbSNP
rs989229957 221 dbSNP
rs1371773890 225 dbSNP
rs1440136986 227 dbSNP
rs957739063 228 dbSNP
rs911284368 236 dbSNP
rs1318566297 237 dbSNP
rs1483840485 239 dbSNP
rs769333918 251 dbSNP
rs930490496 253 dbSNP
rs1201749021 254 dbSNP
rs1211215970 258 dbSNP
rs1273301944 262 dbSNP
rs143229941 263 dbSNP
rs576215661 273 dbSNP
rs1232273870 274 dbSNP
rs1332481316 281 dbSNP
rs73566928 282 dbSNP
rs1034698891 296 dbSNP
rs1451941832 300 dbSNP
rs981704800 302 dbSNP
rs1395380329 303 dbSNP
rs969130290 303 dbSNP
rs1297695569 311 dbSNP
rs35076856 316 dbSNP
rs1023312093 317 dbSNP
rs1010599069 323 dbSNP
rs1332355890 333 dbSNP
rs1012115456 337 dbSNP
rs748117764 340 dbSNP
rs542885033 346 dbSNP
rs1391841053 350 dbSNP
rs113044612 352 dbSNP
rs1333726322 358 dbSNP
rs1392775990 362 dbSNP
rs1234791793 366 dbSNP
rs534714866 370 dbSNP
rs1273400141 371 dbSNP
rs1026740741 377 dbSNP
rs995564030 385 dbSNP
rs139875462 387 dbSNP
rs760442190 388 dbSNP
rs897223044 389 dbSNP
rs1037019762 393 dbSNP
rs944030393 401 dbSNP
rs554098570 402 dbSNP
rs1481912608 405 dbSNP
rs936559265 406 dbSNP
rs181186987 408 dbSNP
rs891413292 410 dbSNP
rs1050430918 416 dbSNP
rs1031587228 417 dbSNP
rs932878552 420 dbSNP
rs1418846117 421 dbSNP
rs1474966191 425 dbSNP
rs1238233418 426 dbSNP
rs778948051 427 dbSNP
rs780342287 427 dbSNP
rs749164545 429 dbSNP
rs750711937 429 dbSNP
rs1212711014 430 dbSNP
rs1462460759 431 dbSNP
rs901389862 431 dbSNP
rs1041083415 433 dbSNP
rs1006865850 434 dbSNP
rs1416375968 435 dbSNP
rs889776229 435 dbSNP
rs1266997543 437 dbSNP
rs1231010107 450 dbSNP
rs1221958998 454 dbSNP
rs1297122959 456 dbSNP
rs1186028740 458 dbSNP
rs1228858837 458 dbSNP
rs1251235076 458 dbSNP
rs1323283367 458 dbSNP
rs1394399577 458 dbSNP
rs1429175956 458 dbSNP
rs1436433858 458 dbSNP
rs143976687 458 dbSNP
rs147659556 458 dbSNP
rs1482318749 458 dbSNP
rs55753437 458 dbSNP
rs59359060 458 dbSNP
rs71340612 458 dbSNP
rs758231406 458 dbSNP
rs765224486 458 dbSNP
rs79749608 458 dbSNP
rs878892310 458 dbSNP
rs1290248288 459 dbSNP
rs1313272677 459 dbSNP
rs1362118315 459 dbSNP
rs751841442 459 dbSNP
rs776529948 459 dbSNP
rs1213475072 471 dbSNP
rs1048532658 477 dbSNP
rs1340679263 479 dbSNP
rs931382330 480 dbSNP
rs190264892 483 dbSNP
rs143857841 484 dbSNP
rs1208344862 489 dbSNP
rs940621534 505 dbSNP
rs558276473 507 dbSNP
rs1244044624 509 dbSNP
rs1379238014 514 dbSNP
rs1486272583 516 dbSNP
rs1186004300 521 dbSNP
rs1246202911 526 dbSNP
rs1455547767 527 dbSNP
rs927847826 529 dbSNP
rs1394309208 530 dbSNP
rs1310022722 535 dbSNP
rs1432620372 540 dbSNP
rs936422020 547 dbSNP
rs1160925466 550 dbSNP
rs377412405 551 dbSNP
rs1345427361 561 dbSNP
rs117158128 569 dbSNP
rs1429524786 569 dbSNP
rs969056658 575 dbSNP
rs1443806815 576 dbSNP
rs1304776435 577 dbSNP
rs1370797045 588 dbSNP
rs1217827274 589 dbSNP
rs1317754960 590 dbSNP
rs1215267449 594 dbSNP
rs1266345434 612 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084064. RNA binding protein: AGO2. Condition:CLIP_noemetine_AbnovaAb HITS-CLIP data was present in GSM1084068. RNA binding protein: AGO2. Condition:CLIP_noemetine_SigmaAb HITS-CLIP data was present in GSM1084072. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep1_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084064
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_AbnovaAb
Location of target site ENST00000542575.2 | 3UTR | UGAUCAUGCCACUGCACUCCAGCCUGGGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084068
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_SigmaAb
Location of target site ENST00000542575.2 | 3UTR | UGAUCAUGCCACUGCACUCCAGCCUGGGCAAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1084072
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep1_AbnovaAb
Location of target site ENST00000542575.2 | 3UTR | AGCUUGCAGUGAGCCGAGAUUGUGCCACUGCACUCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
394 hsa-miR-5698 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT082563 SLC1A5 solute carrier family 1 member 5 2 2
MIRT083003 PNPLA6 patatin like phospholipase domain containing 6 2 2
MIRT112205 BTG2 BTG anti-proliferation factor 2 2 2
MIRT151487 ZBTB7A zinc finger and BTB domain containing 7A 2 2
MIRT178950 C11ORF57 chromosome 11 open reading frame 57 2 2
MIRT183137 WEE1 WEE1 G2 checkpoint kinase 2 4
MIRT189776 CDADC1 cytidine and dCMP deaminase domain containing 1 2 2
MIRT248907 UBE2N ubiquitin conjugating enzyme E2 N 2 2
MIRT273914 ANKRD52 ankyrin repeat domain 52 2 2
MIRT288607 DCAF7 DDB1 and CUL4 associated factor 7 2 4
MIRT442328 WNT9B Wnt family member 9B 2 2
MIRT449084 XPO6 exportin 6 2 2
MIRT451184 PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 2 2
MIRT451902 ILK integrin linked kinase 2 2
MIRT452452 SORCS2 sortilin related VPS10 domain containing receptor 2 2 2
MIRT453627 SLC4A2 solute carrier family 4 member 2 2 2
MIRT454222 OSBPL10 oxysterol binding protein like 10 2 15
MIRT454337 CDKL1 cyclin dependent kinase like 1 2 2
MIRT454783 STOML3 stomatin like 3 2 2
MIRT455051 MEN1 menin 1 2 2
MIRT455160 SUV39H1 suppressor of variegation 3-9 homolog 1 2 2
MIRT456072 AFF2 AF4/FMR2 family member 2 2 6
MIRT456908 DDA1 DET1 and DDB1 associated 1 2 2
MIRT457175 ERC1 ELKS/RAB6-interacting/CAST family member 1 2 4
MIRT457209 THSD4 thrombospondin type 1 domain containing 4 2 2
MIRT457382 CAMK2A calcium/calmodulin dependent protein kinase II alpha 2 2
MIRT458322 SALL2 spalt like transcription factor 2 2 2
MIRT458439 RPRM reprimo, TP53 dependent G2 arrest mediator homolog 2 2
MIRT459561 NLGN2 neuroligin 2 2 2
MIRT459900 PIGO phosphatidylinositol glycan anchor biosynthesis class O 2 12
MIRT459913 HHIP hedgehog interacting protein 2 11
MIRT459944 POC1A POC1 centriolar protein A 2 2
MIRT460205 FGFR4 fibroblast growth factor receptor 4 2 2
MIRT460674 RNF157 ring finger protein 157 2 2
MIRT461926 TNFSF14 TNF superfamily member 14 2 2
MIRT462057 CCDC77 coiled-coil domain containing 77 2 4
MIRT462586 MYL12A myosin light chain 12A 2 2
MIRT463832 WSB1 WD repeat and SOCS box containing 1 2 2
MIRT464055 WAC WW domain containing adaptor with coiled-coil 2 2
MIRT464605 UBE4B ubiquitination factor E4B 2 2
MIRT464679 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 2
MIRT465463 TOR2A torsin family 2 member A 2 2
MIRT465942 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 2
MIRT466023 TMEM189 transmembrane protein 189 2 2
MIRT466616 TARDBP TAR DNA binding protein 2 2
MIRT466912 STK38 serine/threonine kinase 38 2 10
MIRT468341 SF3B3 splicing factor 3b subunit 3 2 2
MIRT468600 SERBP1 SERPINE1 mRNA binding protein 1 2 2
MIRT468874 RREB1 ras responsive element binding protein 1 2 2
MIRT468908 RPS6KA4 ribosomal protein S6 kinase A4 2 2
MIRT468966 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 2
MIRT469206 RICTOR RPTOR independent companion of MTOR complex 2 2 2
MIRT469313 RGP1 RGP1 homolog, RAB6A GEF complex partner 1 2 2
MIRT469788 RAB15 RAB15, member RAS oncogene family 2 6
MIRT469944 PTPRF protein tyrosine phosphatase, receptor type F 2 2
MIRT470006 PTPLB 3-hydroxyacyl-CoA dehydratase 2 1 1
MIRT470139 PSME3 proteasome activator subunit 3 2 2
MIRT470229 PRRC2A proline rich coiled-coil 2A 2 2
MIRT470591 POTEM POTE ankyrin domain family member M 2 2
MIRT470621 POTEG POTE ankyrin domain family member G 2 2
MIRT470946 PKM pyruvate kinase, muscle 2 2
MIRT471022 PISD phosphatidylserine decarboxylase 2 10
MIRT472851 MTHFR methylenetetrahydrofolate reductase 2 2
MIRT473309 MEX3A mex-3 RNA binding family member A 2 2
MIRT473965 LRRC58 leucine rich repeat containing 58 2 2
MIRT474405 KLHL28 kelch like family member 28 2 8
MIRT474837 KHSRP KH-type splicing regulatory protein 2 2
MIRT476496 GATAD2A GATA zinc finger domain containing 2A 2 2
MIRT476846 FHL2 four and a half LIM domains 2 2 4
MIRT477605 EFNA3 ephrin A3 2 2
MIRT477868 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 2 2
MIRT480140 CALR calreticulin 2 2
MIRT480694 BRPF1 bromodomain and PHD finger containing 1 2 2
MIRT481248 ATXN7L3 ataxin 7 like 3 2 2
MIRT482301 AGO2 argonaute 2, RISC catalytic component 2 17
MIRT482521 ACTB actin beta 2 2
MIRT482671 NXN nucleoredoxin 2 4
MIRT482985 CSTF2 cleavage stimulation factor subunit 2 2 2
MIRT483121 ONECUT3 one cut homeobox 3 2 4
MIRT483251 CITED4 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4 2 4
MIRT483299 SLC35C2 solute carrier family 35 member C2 2 4
MIRT483399 SPATA6 spermatogenesis associated 6 2 4
MIRT483489 STMN3 stathmin 3 2 4
MIRT483579 SLC26A9 solute carrier family 26 member 9 2 2
MIRT483648 QSOX2 quiescin sulfhydryl oxidase 2 2 4
MIRT483855 EMID1 EMI domain containing 1 2 2
MIRT484138 LRRC45 leucine rich repeat containing 45 2 4
MIRT484191 SUMO1 small ubiquitin-like modifier 1 2 4
MIRT484273 AIP aryl hydrocarbon receptor interacting protein 2 4
MIRT484351 GATA6 GATA binding protein 6 2 10
MIRT484408 SNX19 sorting nexin 19 2 2
MIRT484469 DDX6 DEAD-box helicase 6 2 2
MIRT484525 POLD3 DNA polymerase delta 3, accessory subunit 2 2
MIRT484570 HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 2 2
MIRT484602 SIX3 SIX homeobox 3 2 6
MIRT484752 ABCC6 ATP binding cassette subfamily C member 6 2 4
MIRT485261 PLEKHA3 pleckstrin homology domain containing A3 2 2
MIRT485484 IGF1R insulin like growth factor 1 receptor 2 8
MIRT485539 GP5 glycoprotein V platelet 2 2
MIRT485601 FOSL1 FOS like 1, AP-1 transcription factor subunit 2 4
MIRT485919 PGPEP1 pyroglutamyl-peptidase I 2 4
MIRT485960 RTBDN retbindin 2 2
MIRT486287 KBTBD3 kelch repeat and BTB domain containing 3 2 2
MIRT486371 TIGD5 tigger transposable element derived 5 2 2
MIRT486428 NDUFA5 NADH:ubiquinone oxidoreductase subunit A5 2 2
MIRT486604 METTL6 methyltransferase like 6 2 2
MIRT486717 MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B 2 4
MIRT486818 NDOR1 NADPH dependent diflavin oxidoreductase 1 2 2
MIRT486842 SLC9A3R2 SLC9A3 regulator 2 2 2
MIRT486884 TSPYL4 TSPY like 4 2 4
MIRT486930 DTX2 deltex E3 ubiquitin ligase 2 2 2
MIRT487106 SCARF2 scavenger receptor class F member 2 2 2
MIRT487151 LINGO3 leucine rich repeat and Ig domain containing 3 2 2
MIRT487182 NFASC neurofascin 2 4
MIRT487439 TFAP2B transcription factor AP-2 beta 2 4
MIRT487574 FAM83H family with sequence similarity 83 member H 2 4
MIRT487721 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2 2
MIRT487892 CST9 cystatin 9 2 2
MIRT488010 GDF5OS growth differentiation factor 5 opposite strand 2 2
MIRT488087 DLGAP3 DLG associated protein 3 2 4
MIRT488166 PRRC2B proline rich coiled-coil 2B 2 4
MIRT488180 MAT1A methionine adenosyltransferase 1A 2 2
MIRT488274 PARS2 prolyl-tRNA synthetase 2, mitochondrial 2 2
MIRT488308 LDOC1 LDOC1, regulator of NFKB signaling 2 2
MIRT488468 B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 2 2
MIRT488486 OR2C3 olfactory receptor family 2 subfamily C member 3 2 2
MIRT488635 HAND2 heart and neural crest derivatives expressed 2 2 2
MIRT489000 FBXO40 F-box protein 40 2 2
MIRT489033 PRPF4B pre-mRNA processing factor 4B 2 2
MIRT489111 PPFIA3 PTPRF interacting protein alpha 3 2 2
MIRT489136 C5orf38 chromosome 5 open reading frame 38 2 2
MIRT489524 MRE11A MRE11 homolog, double strand break repair nuclease 2 14
MIRT489643 ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2 4
MIRT489711 CALML3 calmodulin like 3 2 2
MIRT489766 GRINA glutamate ionotropic receptor NMDA type subunit associated protein 1 2 2
MIRT490023 PIEZO1 piezo type mechanosensitive ion channel component 1 2 2
MIRT490068 PRRT2 proline rich transmembrane protein 2 2 4
MIRT490128 FN3K fructosamine 3 kinase 2 2
MIRT490196 PKNOX2 PBX/knotted 1 homeobox 2 2 2
MIRT490321 ANK1 ankyrin 1 2 4
MIRT490521 KIAA1715 lunapark, ER junction formation factor 2 2
MIRT490601 SLC47A1 solute carrier family 47 member 1 2 4
MIRT490981 USP22 ubiquitin specific peptidase 22 2 2
MIRT491139 GRWD1 glutamate rich WD repeat containing 1 2 2
MIRT491160 LRP3 LDL receptor related protein 3 2 2
MIRT491610 CCL22 C-C motif chemokine ligand 22 2 2
MIRT492150 STK11 serine/threonine kinase 11 2 2
MIRT492224 SLC48A1 solute carrier family 48 member 1 2 2
MIRT492550 PRX periaxin 2 2
MIRT492833 NRGN neurogranin 2 2
MIRT492930 NEUROD2 neuronal differentiation 2 2 2
MIRT493019 NACC1 nucleus accumbens associated 1 2 2
MIRT494026 DUSP7 dual specificity phosphatase 7 2 4
MIRT494206 CLIP2 CAP-Gly domain containing linker protein 2 2 2
MIRT494500 BDNF-AS BDNF antisense RNA 2 2
MIRT494785 ANKRD13B ankyrin repeat domain 13B 2 4
MIRT494826 ADCY9 adenylate cyclase 9 2 2
MIRT495707 PADI1 peptidyl arginine deiminase 1 2 2
MIRT497656 PRMT3 protein arginine methyltransferase 3 2 2
MIRT499003 CCDC50 coiled-coil domain containing 50 2 2
MIRT499302 ZNF485 zinc finger protein 485 2 10
MIRT499635 CREB3L2 cAMP responsive element binding protein 3 like 2 2 2
MIRT499751 CIRH1A UTP4, small subunit processome component 2 10
MIRT501420 RAB11FIP4 RAB11 family interacting protein 4 2 2
MIRT501647 PHLDA3 pleckstrin homology like domain family A member 3 2 6
MIRT501695 PCGF3 polycomb group ring finger 3 2 6
MIRT508519 GDI1 GDP dissociation inhibitor 1 2 4
MIRT509941 TOMM70A translocase of outer mitochondrial membrane 70 2 6
MIRT512054 DIRAS2 DIRAS family GTPase 2 2 4
MIRT515502 GTF2F1 general transcription factor IIF subunit 1 2 2
MIRT522549 MCAM melanoma cell adhesion molecule 2 4
MIRT522609 MAP7D1 MAP7 domain containing 1 2 4
MIRT523754 FBXO27 F-box protein 27 2 4
MIRT526831 PHC1 polyhomeotic homolog 1 2 2
MIRT527029 NAGK N-acetylglucosamine kinase 2 4
MIRT531630 C19orf52 translocase of inner mitochondrial membrane 29 2 4
MIRT531906 SLC4A1 solute carrier family 4 member 1 (Diego blood group) 2 2
MIRT533105 YIPF4 Yip1 domain family member 4 2 4
MIRT535464 PARVB parvin beta 2 4
MIRT536735 HSPA4L heat shock protein family A (Hsp70) member 4 like 2 2
MIRT539164 AR androgen receptor 2 2
MIRT539517 ABCF1 ATP binding cassette subfamily F member 1 2 4
MIRT544667 AP1S1 adaptor related protein complex 1 sigma 1 subunit 2 2
MIRT553363 TRIM44 tripartite motif containing 44 2 2
MIRT555413 PPIC peptidylprolyl isomerase C 2 2
MIRT555907 ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 2 2
MIRT562190 HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 2 2
MIRT568799 VPS37D VPS37D, ESCRT-I subunit 2 2
MIRT568947 RUNX3 runt related transcription factor 3 2 2
MIRT569004 CXorf36 chromosome X open reading frame 36 2 2
MIRT569307 CC2D1B coiled-coil and C2 domain containing 1B 2 2
MIRT569580 PRELP proline and arginine rich end leucine rich repeat protein 2 2
MIRT569817 CRMP1 collapsin response mediator protein 1 2 2
MIRT570007 COL1A2 collagen type I alpha 2 chain 2 2
MIRT570038 ZNF562 zinc finger protein 562 2 2
MIRT570041 PKNOX1 PBX/knotted 1 homeobox 1 2 2
MIRT570190 RAP1GAP2 RAP1 GTPase activating protein 2 2 2
MIRT570471 THRA thyroid hormone receptor, alpha 2 2
MIRT571191 C9orf62 chromosome 9 open reading frame 62 2 2
MIRT571302 IWS1 IWS1, SUPT6H interacting protein 2 2
MIRT572998 RPP25 ribonuclease P and MRP subunit p25 2 2
MIRT574627 LPCAT3 lysophosphatidylcholine acyltransferase 3 2 2
MIRT575195 Entpd4 ectonucleoside triphosphate diphosphohydrolase 4 2 2
MIRT575273 Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 2 2
MIRT575292 Osbpl10 oxysterol binding protein-like 10 2 9
MIRT575317 Fbxo6 F-box protein 6 2 2
MIRT575370 Ang angiogenin, ribonuclease, RNase A family, 5 2 3
MIRT575728 Hhip Hedgehog-interacting protein 2 7
MIRT575836 Ago2 argonaute RISC catalytic subunit 2 2 10
MIRT607039 IDS iduronate 2-sulfatase 2 2
MIRT607059 POM121L7 POM121 transmembrane nucleoporin like 7 pseudogene 2 2
MIRT607482 HEBP2 heme binding protein 2 2 2
MIRT607517 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 2
MIRT607648 BTN3A2 butyrophilin subfamily 3 member A2 2 2
MIRT607706 LIMS1 LIM zinc finger domain containing 1 2 4
MIRT607788 RHBDL2 rhomboid like 2 2 2
MIRT607920 ANG angiogenin 2 3
MIRT607956 SNX22 sorting nexin 22 2 2
MIRT608067 ZFP14 ZFP14 zinc finger protein 2 2
MIRT608137 SYAP1 synapse associated protein 1 2 2
MIRT615360 CCNF cyclin F 2 2
MIRT616099 HOXB5 homeobox B5 2 2
MIRT616273 HOXD11 homeobox D11 2 2
MIRT617435 CCS copper chaperone for superoxide dismutase 2 2
MIRT617544 MTO1 mitochondrial tRNA translation optimization 1 2 2
MIRT617665 RSRC1 arginine and serine rich coiled-coil 1 2 2
MIRT618920 MEAF6 MYST/Esa1 associated factor 6 2 2
MIRT619113 CD40LG CD40 ligand 2 2
MIRT619239 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT619684 AGMO alkylglycerol monooxygenase 2 2
MIRT620089 YME1L1 YME1 like 1 ATPase 2 2
MIRT620560 WBSCR27 methyltransferase like 27 2 4
MIRT622973 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT625263 AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 2 2
MIRT625391 AKR7L aldo-keto reductase family 7 like (gene/pseudogene) 2 2
MIRT625689 OPTN optineurin 2 2
MIRT626085 MKLN1 muskelin 1 2 2
MIRT626427 CHDH choline dehydrogenase 2 2
MIRT626484 CEP89 centrosomal protein 89 2 2
MIRT627132 HS3ST1 heparan sulfate-glucosamine 3-sulfotransferase 1 2 2
MIRT627343 TSHZ2 teashirt zinc finger homeobox 2 2 2
MIRT627431 TAS2R5 taste 2 receptor member 5 2 2
MIRT628072 KAT7 lysine acetyltransferase 7 2 4
MIRT630118 ARHGEF5 Rho guanine nucleotide exchange factor 5 2 2
MIRT631189 TSPAN14 tetraspanin 14 2 2
MIRT631257 CENPM centromere protein M 2 2
MIRT631396 IL2RA interleukin 2 receptor subunit alpha 2 2
MIRT631784 CLK4 CDC like kinase 4 2 2
MIRT631963 YIPF5 Yip1 domain family member 5 2 2
MIRT632884 GINM1 glycoprotein integral membrane 1 2 2
MIRT633234 ZNF573 zinc finger protein 573 2 2
MIRT633529 PGBD5 piggyBac transposable element derived 5 2 2
MIRT634331 SGOL1 shugoshin 1 2 2
MIRT634593 KIAA1919 major facilitator superfamily domain containing 4B 2 2
MIRT635230 QPRT quinolinate phosphoribosyltransferase 2 2
MIRT635317 BMS1 BMS1, ribosome biogenesis factor 2 2
MIRT635560 LEPREL1 prolyl 3-hydroxylase 2 1 1
MIRT636440 LRCH3 leucine rich repeats and calponin homology domain containing 3 2 2
MIRT636511 FMN1 formin 1 2 2
MIRT636748 SLC16A5 solute carrier family 16 member 5 2 2
MIRT637126 BAMBI BMP and activin membrane bound inhibitor 2 2
MIRT637279 IBA57 IBA57 homolog, iron-sulfur cluster assembly 2 2
MIRT637523 RGS9BP regulator of G protein signaling 9 binding protein 2 2
MIRT637780 OLA1 Obg like ATPase 1 2 2
MIRT638439 PLXDC2 plexin domain containing 2 2 2
MIRT642316 ZNF730 zinc finger protein 730 2 2
MIRT643075 PTPLAD2 3-hydroxyacyl-CoA dehydratase 4 1 1
MIRT646654 FNBP1 formin binding protein 1 2 2
MIRT647008 ADCY2 adenylate cyclase 2 2 2
MIRT647090 SEC23B Sec23 homolog B, coat complex II component 2 2
MIRT647701 NFX1 nuclear transcription factor, X-box binding 1 2 4
MIRT648031 FADS6 fatty acid desaturase 6 2 2
MIRT649175 DNPEP aspartyl aminopeptidase 2 2
MIRT649654 TEP1 telomerase associated protein 1 2 2
MIRT652394 TMEM40 transmembrane protein 40 2 2
MIRT653681 SLC25A33 solute carrier family 25 member 33 2 2
MIRT654114 RPS6KA5 ribosomal protein S6 kinase A5 2 2
MIRT655239 PEX26 peroxisomal biogenesis factor 26 2 2
MIRT656467 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2 2
MIRT659463 CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2 4
MIRT661094 SPIB Spi-B transcription factor 2 2
MIRT661287 LIN52 lin-52 DREAM MuvB core complex component 2 2
MIRT662226 PGBD4 piggyBac transposable element derived 4 2 2
MIRT662534 MTAP methylthioadenosine phosphorylase 2 2
MIRT662614 MCM8 minichromosome maintenance 8 homologous recombination repair factor 2 2
MIRT662731 LRRC3C leucine rich repeat containing 3C 2 2
MIRT662952 JPH2 junctophilin 2 2 2
MIRT663333 ZNF74 zinc finger protein 74 2 2
MIRT663487 IYD iodotyrosine deiodinase 2 2
MIRT663896 MRI1 methylthioribose-1-phosphate isomerase 1 2 2
MIRT663965 ZNF786 zinc finger protein 786 2 2
MIRT664410 TIGD6 tigger transposable element derived 6 2 2
MIRT664462 ZYG11B zyg-11 family member B, cell cycle regulator 2 2
MIRT664579 HSD17B12 hydroxysteroid 17-beta dehydrogenase 12 2 2
MIRT664950 PTCD3 pentatricopeptide repeat domain 3 2 2
MIRT664964 TDRD1 tudor domain containing 1 2 2
MIRT665011 ELK1 ELK1, ETS transcription factor 2 2
MIRT665045 C3 complement C3 2 2
MIRT665190 ESF1 ESF1 nucleolar pre-rRNA processing protein homolog 2 2
MIRT665350 XKR4 XK related 4 2 2
MIRT665441 WDR17 WD repeat domain 17 2 2
MIRT665799 TMEM168 transmembrane protein 168 2 2
MIRT665890 TCEANC2 transcription elongation factor A N-terminal and central domain containing 2 2 2
MIRT666313 SLC16A10 solute carrier family 16 member 10 2 4
MIRT666476 SBNO1 strawberry notch homolog 1 2 2
MIRT666509 RNF170 ring finger protein 170 2 2
MIRT666689 RBM23 RNA binding motif protein 23 2 2
MIRT666706 RBL1 RB transcriptional corepressor like 1 2 2
MIRT666758 RAB10 RAB10, member RAS oncogene family 2 2
MIRT667352 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT667468 MAPK1 mitogen-activated protein kinase 1 2 2
MIRT667533 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 2
MIRT667548 LRAT lecithin retinol acyltransferase 2 2
MIRT668076 GMEB1 glucocorticoid modulatory element binding protein 1 2 2
MIRT668109 GK5 glycerol kinase 5 (putative) 2 2
MIRT668160 GDE1 glycerophosphodiester phosphodiesterase 1 2 2
MIRT668338 STXBP2 syntaxin binding protein 2 2 2
MIRT668497 ESYT2 extended synaptotagmin 2 2 2
MIRT668939 CNKSR3 CNKSR family member 3 2 2
MIRT669286 C17orf85 nuclear cap binding subunit 3 2 2
MIRT669454 ATL3 atlastin GTPase 3 2 2
MIRT669539 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT669769 CNDP1 carnosine dipeptidase 1 2 2
MIRT669850 BROX BRO1 domain and CAAX motif containing 2 4
MIRT670009 TECPR1 tectonin beta-propeller repeat containing 1 2 2
MIRT670056 VEZT vezatin, adherens junctions transmembrane protein 2 2
MIRT670190 ERGIC1 endoplasmic reticulum-golgi intermediate compartment 1 2 2
MIRT670898 COMMD9 COMM domain containing 9 2 2
MIRT671103 ZNF841 zinc finger protein 841 2 2
MIRT671346 SMG1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 2 2
MIRT671541 UEVLD UEV and lactate/malate dehyrogenase domains 2 2
MIRT671664 HEYL hes related family bHLH transcription factor with YRPW motif-like 2 2
MIRT672192 F2 coagulation factor II, thrombin 2 2
MIRT672243 SIK2 salt inducible kinase 2 2 2
MIRT672591 NKPD1 NTPase KAP family P-loop domain containing 1 2 2
MIRT672894 KRBA2 KRAB-A domain containing 2 2 2
MIRT672953 ZNF655 zinc finger protein 655 2 2
MIRT673091 SYNPO2L synaptopodin 2 like 2 2
MIRT673166 TMEM56 transmembrane protein 56 2 2
MIRT673245 INO80 INO80 complex subunit 2 2
MIRT673291 RNF19B ring finger protein 19B 2 2
MIRT673569 KDELC2 KDEL motif containing 2 2 2
MIRT673731 TCF23 transcription factor 23 2 2
MIRT673765 MRPL17 mitochondrial ribosomal protein L17 2 2
MIRT674334 KCMF1 potassium channel modulatory factor 1 2 2
MIRT674385 MYCBP MYC binding protein 2 2
MIRT675137 MOGAT1 monoacylglycerol O-acyltransferase 1 2 4
MIRT675573 WWC1 WW and C2 domain containing 1 2 2
MIRT675592 ZNF106 zinc finger protein 106 2 2
MIRT676019 C9orf69 transmembrane protein 250 2 2
MIRT676184 GSTM3 glutathione S-transferase mu 3 2 2
MIRT676419 PLEKHM3 pleckstrin homology domain containing M3 2 2
MIRT676553 VSIG1 V-set and immunoglobulin domain containing 1 2 2
MIRT676590 ARIH2OS ariadne RBR E3 ubiquitin protein ligase 2 opposite strand 2 2
MIRT677063 ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 2 2
MIRT677475 PROSER2 proline and serine rich 2 2 2
MIRT677615 ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 2 2
MIRT677653 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT677683 SCO1 SCO1, cytochrome c oxidase assembly protein 2 2
MIRT677740 GNB4 G protein subunit beta 4 2 2
MIRT678386 RSPH3 radial spoke head 3 homolog 2 2
MIRT678466 RNF222 ring finger protein 222 2 2
MIRT680212 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 2
MIRT680334 ZNF281 zinc finger protein 281 2 2
MIRT680382 OXA1L OXA1L, mitochondrial inner membrane protein 2 2
MIRT682818 FLG2 filaggrin family member 2 2 2
MIRT682875 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT684250 TBXA2R thromboxane A2 receptor 2 2
MIRT684400 TMEM180 major facilitator superfamily domain containing 13A 2 2
MIRT685268 KIAA1143 KIAA1143 2 2
MIRT686053 KCNA7 potassium voltage-gated channel subfamily A member 7 2 2
MIRT688031 GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 2 2
MIRT693883 C3orf62 chromosome 3 open reading frame 62 2 2
MIRT694337 CHST6 carbohydrate sulfotransferase 6 2 2
MIRT696097 SETD1A SET domain containing 1A 2 2
MIRT702168 LYRM4 LYR motif containing 4 2 2
MIRT702652 ITGA3 integrin subunit alpha 3 2 2
MIRT706195 ACOT9 acyl-CoA thioesterase 9 2 2
MIRT706652 RNF216 ring finger protein 216 2 2
MIRT706697 GPR155 G protein-coupled receptor 155 2 2
MIRT706769 ANKRD36 ankyrin repeat domain 36 2 2
MIRT706839 DNAJB13 DnaJ heat shock protein family (Hsp40) member B13 2 2
MIRT706853 MAFF MAF bZIP transcription factor F 2 2
MIRT706887 ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 2 2
MIRT706953 FANCC Fanconi anemia complementation group C 2 2
MIRT706971 XPO5 exportin 5 2 2
MIRT707007 RRP36 ribosomal RNA processing 36 2 2
MIRT707021 ACTR5 ARP5 actin related protein 5 homolog 2 2
MIRT709363 SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 2 2
MIRT712145 TAOK1 TAO kinase 1 2 2
MIRT712435 KIAA1161 myogenesis regulating glycosidase (putative) 2 2
MIRT713364 STK35 serine/threonine kinase 35 2 2
MIRT721673 SLFN12 schlafen family member 12 2 2
MIRT724193 MED7 mediator complex subunit 7 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-5698 Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-miR-5698 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-5698 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-5698 Docetaxel+Cisplatin+5-Fluorouracil resistant tissue (hypopharyngeal squamous cell carcinoma)

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