miRTarBase - #MIRT082888


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pre-miRNA Information
pre-miRNA hsa-mir-642b   
Genomic Coordinates chr19: 45674932 - 45675008
Description Homo sapiens miR-642b stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-642b-3p
Sequence 47| AGACACAUUUGGAGAGGGACCC |68
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN24410683 6 COSMIC
COSN8407659 14 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs778534861 2 dbSNP
rs111664333 4 dbSNP
rs998995912 5 dbSNP
rs1206620651 6 dbSNP
rs1317907103 7 dbSNP
rs374751972 13 dbSNP
rs78902025 15 dbSNP
rs775648115 20 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol ZNF543   
Synonyms -
Description zinc finger protein 543
Transcript NM_213598   
Expression
Putative miRNA Targets on ZNF543
3'UTR of ZNF543
(miRNA target sites are highlighted)		 
>ZNF543|NM_213598|3'UTR
   1 AAGGGAACATCTTACCATCTGGCCATTCACACTGAAGAGAAACTTCATAAGCATCCTCTCTTTGAGAAAACGTGTAATAG
  81 ATGATCATTTGTCGTCTAAACAATCAAGTTAGAAATTGAACCAGCCTGGAGTCTTATTCTCCACCTGAGAATTCACCCAT
 161 GAGAGAGACCCAGTGGTTGCTATGCACTTAGGAAAACTTTCAGCCACATCTTTCTTCTTAGTTTACAGTGAAATATTATC
 241 TCAGGGATATTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGGGATCTCGGCT
 321 CACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACCCGCCA
 401 CTACGCCTGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTTTTAGCCGGGATGGTCTCGATCTCCTGACC
 481 TCGTGATCCGCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCATCTCAGGGATATT
 561 TAAACAAAGGAAGAGGAAATATAGGGAAGAGAAAGAAACCACAGCTTCTTTTAGACTTGTCTGACAAGCCTATGGCAATT
 641 TTGTCGTCCCTTTGTTATTTTATGTGGGAGAGGGAAATGTTTCAGAAACGAAAGATCTCATCCCCTTTATTTTTCTGTGT
 721 ATGCATTCACTGCTGCCCAGTGTCAGAACAGTTATACAAACGAGGGCTTGAAAACATTTTGTGAAAACTTGCTTAGTCCT
 801 GCAACGTTCTCCACTCTCGAGGTGCAGAAGCATACATCTTTATAAAAAATATGGAGGCTTGAGTTATGAAACACTTTTAT
 881 AAGGAGATAAGGATGTACATATGTTTGGACACATTGTCCACTTCAGATGCTTGTTTAAAAAAATGTTTCACCATGTGTCT
 961 TTACCCAATACACATACTTTTTCTTGATGTGGATTTACTTTTTTTTTTTTTTTTTAAGTTTTCCTGGGATAGGGATGATA
1041 GTGTAATTGTTCATGCCCACAGTAATCCTGGGAATCTTAGTTTTTTCCTATGATTGTGGTTTCTCAGCTTCTTTACCTCT
1121 CCTTTGAGTTAGGTCCACCTCAGTTTTCTAAAGGTCAAATTAAGGCCCCCCCAAAAATACAGTATGTAGCTGAATTCCTT
1201 TGAAAGATCATGATAAACTCAGAAGAACAAACATAGAAGGAATGTCATTTTTAATCTTTTTAAAGAGTGTGTGAAAATTC
1281 ACTTTAACTGGAATTTTAACAGGCAAGCCGGCATGCATATATGTAGGGATGTGTGACTTTCACAGTTGTCACCATGGACT
1361 TAGGCTTGATTAAAATGCTACACATTTAGAGCGTTTTGTAATTCCTTTTTTATATTTTTAAGACTAGATTTTGAGCCATG
1441 TGATAGTTTTACCTCATATTAAATATATTGTACAGAAGTAAAAATAATCATGTATTCACTTTGAACTCCTC
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cccAGGGAGAGGUUUACACAGa 5'
             | ::|| ||  ||||||| 
Target 5' aaaTGTTTCACC--ATGTGTCt 3'
 941 - 960 151.00 -13.50
2 
miRNA  3' cccAGGGAGAGGU-UUACACAga 5'
             ||::|:|  | |:|||||  
Target 5' taaTCTTTTTAAAGAGTGTGTga 3'
 1252 - 1274 123.00 -11.60
3 
miRNA  3' cccagggAGAGGUUUACACAga 5'
                 | |  ::||||||  
Target 5' gcatataTGTAGGGATGTGTga 3'
 1315 - 1336 123.00 -5.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30499224 10 COSMIC
COSN30175087 20 COSMIC
COSN31511246 38 COSMIC
COSN30468198 51 COSMIC
COSN31516975 56 COSMIC
COSN1772784 58 COSMIC
COSN30139154 62 COSMIC
COSN27006226 64 COSMIC
COSN30179641 65 COSMIC
COSN30179607 67 COSMIC
COSN30506803 72 COSMIC
COSN30180297 81 COSMIC
COSN30192051 106 COSMIC
COSN31599951 150 COSMIC
COSN16682378 162 COSMIC
COSN27054316 539 COSMIC
COSN6669933 620 COSMIC
COSN6148051 691 COSMIC
COSN21567480 700 COSMIC
COSN22770256 814 COSMIC
COSN4907489 879 COSMIC
COSN20116150 1016 COSMIC
COSN27272259 1016 COSMIC
COSN16430033 1023 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs143736129 4 dbSNP
rs1227350917 6 dbSNP
rs1368819572 7 dbSNP
rs747020312 10 dbSNP
rs1337467643 12 dbSNP
rs1410470470 13 dbSNP
rs1401340350 15 dbSNP
rs371065636 15 dbSNP
rs745411872 15 dbSNP
rs757558196 17 dbSNP
rs781509396 18 dbSNP
rs746077353 26 dbSNP
rs1429695089 30 dbSNP
rs768641758 33 dbSNP
rs866885430 36 dbSNP
rs1472288306 41 dbSNP
rs113669012 45 dbSNP
rs1420282875 51 dbSNP
rs1406946270 52 dbSNP
rs906621938 56 dbSNP
rs1461600218 58 dbSNP
rs367565035 59 dbSNP
rs956174477 61 dbSNP
rs1011510232 71 dbSNP
rs1021927844 73 dbSNP
rs1281365047 75 dbSNP
rs1291650612 77 dbSNP
rs964543178 79 dbSNP
rs575602494 80 dbSNP
rs974571902 94 dbSNP
rs931322580 95 dbSNP
rs544807005 101 dbSNP
rs1158056872 102 dbSNP
rs763041436 102 dbSNP
rs1325685379 106 dbSNP
rs1413790357 113 dbSNP
rs1369149143 116 dbSNP
rs1048646218 138 dbSNP
rs1177418299 157 dbSNP
rs890026218 159 dbSNP
rs1472199029 164 dbSNP
rs954432718 164 dbSNP
rs1186082504 174 dbSNP
rs942954972 177 dbSNP
rs191218685 181 dbSNP
rs1041231699 183 dbSNP
rs901370343 184 dbSNP
rs1325484689 186 dbSNP
rs866362851 187 dbSNP
rs1286693703 188 dbSNP
rs1224665139 192 dbSNP
rs530296697 194 dbSNP
rs1340020716 196 dbSNP
rs1454515974 198 dbSNP
rs891439086 202 dbSNP
rs1319790006 207 dbSNP
rs1346709223 212 dbSNP
rs1037962635 214 dbSNP
rs1404347458 217 dbSNP
rs916777312 226 dbSNP
rs536609098 227 dbSNP
rs71354045 230 dbSNP
rs1271047266 231 dbSNP
rs1469693429 234 dbSNP
rs969931808 235 dbSNP
rs980029657 238 dbSNP
rs560760003 240 dbSNP
rs1244171863 244 dbSNP
rs1491215614 247 dbSNP
rs1491545423 248 dbSNP
rs138844194 249 dbSNP
rs11355141 250 dbSNP
rs1226049880 250 dbSNP
rs1287829585 250 dbSNP
rs796094957 250 dbSNP
rs960154914 250 dbSNP
rs972817900 252 dbSNP
rs999547622 261 dbSNP
rs1478437236 266 dbSNP
rs1164762314 267 dbSNP
rs1392904605 271 dbSNP
rs1463406200 272 dbSNP
rs984527721 274 dbSNP
rs1388981955 275 dbSNP
rs1168568185 277 dbSNP
rs535209849 279 dbSNP
rs1052924641 280 dbSNP
rs1380123886 283 dbSNP
rs1245267048 294 dbSNP
rs893816219 298 dbSNP
rs1011285303 301 dbSNP
rs1273942749 302 dbSNP
rs1226135366 303 dbSNP
rs1309120127 304 dbSNP
rs1319755430 305 dbSNP
rs1021583090 309 dbSNP
rs1218489512 309 dbSNP
rs1232621039 310 dbSNP
rs1284850581 311 dbSNP
rs1405155140 312 dbSNP
rs868729299 317 dbSNP
rs996041109 318 dbSNP
rs1460929530 323 dbSNP
rs1356848719 324 dbSNP
rs1030152978 327 dbSNP
rs1336811500 334 dbSNP
rs866443483 335 dbSNP
rs1259876210 336 dbSNP
rs1480861158 339 dbSNP
rs954507324 341 dbSNP
rs1485682608 342 dbSNP
rs112438872 349 dbSNP
rs918679289 350 dbSNP
rs1264718827 353 dbSNP
rs1488691649 354 dbSNP
rs963076819 363 dbSNP
rs551842784 365 dbSNP
rs1476461800 367 dbSNP
rs1165958985 374 dbSNP
rs916862697 375 dbSNP
rs984101218 380 dbSNP
rs911264697 383 dbSNP
rs982267319 384 dbSNP
rs1465933422 385 dbSNP
rs1404398611 387 dbSNP
rs942922568 389 dbSNP
rs1178951851 391 dbSNP
rs1041326345 392 dbSNP
rs928154766 393 dbSNP
rs935472596 394 dbSNP
rs1179926839 397 dbSNP
rs568958192 398 dbSNP
rs935517988 399 dbSNP
rs1413672889 400 dbSNP
rs1310516021 403 dbSNP
rs57227955 405 dbSNP
rs1204126421 406 dbSNP
rs893879925 409 dbSNP
rs537506191 425 dbSNP
rs1052844288 431 dbSNP
rs946773654 431 dbSNP
rs1040098383 433 dbSNP
rs1306027351 438 dbSNP
rs1424062515 439 dbSNP
rs1314851652 441 dbSNP
rs1395957756 444 dbSNP
rs891526436 445 dbSNP
rs1339256724 448 dbSNP
rs1453920603 449 dbSNP
rs8108680 450 dbSNP
rs1030227909 452 dbSNP
rs890304556 458 dbSNP
rs1005081741 459 dbSNP
rs1014713754 461 dbSNP
rs1442840412 462 dbSNP
rs963448858 463 dbSNP
rs1021245366 469 dbSNP
rs905572535 470 dbSNP
rs1206556682 472 dbSNP
rs969002862 479 dbSNP
rs567939735 484 dbSNP
rs928181083 487 dbSNP
rs1036033072 490 dbSNP
rs959869970 491 dbSNP
rs935553183 492 dbSNP
rs988708461 493 dbSNP
rs994391761 494 dbSNP
rs1025497966 495 dbSNP
rs952769672 499 dbSNP
rs10417105 500 dbSNP
rs911191196 502 dbSNP
rs1164154800 505 dbSNP
rs1448749507 506 dbSNP
rs553689905 507 dbSNP
rs964042063 516 dbSNP
rs933948478 519 dbSNP
rs1194986273 522 dbSNP
rs1447355808 523 dbSNP
rs1380575877 527 dbSNP
rs1219764024 528 dbSNP
rs1490712322 533 dbSNP
rs1433658596 534 dbSNP
rs977007917 535 dbSNP
rs369876565 537 dbSNP
rs1339226055 538 dbSNP
rs867947981 539 dbSNP
rs922857987 540 dbSNP
rs1376671410 543 dbSNP
rs1300904847 544 dbSNP
rs1466499991 545 dbSNP
rs935626770 548 dbSNP
rs1297597425 550 dbSNP
rs1053015552 554 dbSNP
rs774492030 566 dbSNP
rs1394324587 570 dbSNP
rs915451264 571 dbSNP
rs576685276 583 dbSNP
rs1376835401 586 dbSNP
rs1042798307 588 dbSNP
rs1377957153 591 dbSNP
rs1004751607 602 dbSNP
rs1180756547 608 dbSNP
rs112863913 620 dbSNP
rs1481458999 624 dbSNP
rs1271551303 625 dbSNP
rs539026154 626 dbSNP
rs905499158 630 dbSNP
rs1262862388 633 dbSNP
rs1036589458 639 dbSNP
rs1350075288 643 dbSNP
rs1001167072 646 dbSNP
rs73633730 647 dbSNP
rs1330879627 655 dbSNP
rs1410419538 674 dbSNP
rs184081445 687 dbSNP
rs895702703 690 dbSNP
rs1470760881 691 dbSNP
rs1239126180 710 dbSNP
rs1157914631 726 dbSNP
rs994135278 744 dbSNP
rs117304550 751 dbSNP
rs1234064795 756 dbSNP
rs952530132 757 dbSNP
rs1005600795 762 dbSNP
rs1438828405 771 dbSNP
rs1414220167 773 dbSNP
rs1396493331 782 dbSNP
rs1242930417 797 dbSNP
rs1035269450 802 dbSNP
rs1326103038 805 dbSNP
rs1018388541 806 dbSNP
rs188619983 807 dbSNP
rs1348664012 808 dbSNP
rs1281315070 809 dbSNP
rs1442844935 810 dbSNP
rs10417949 813 dbSNP
rs8108930 819 dbSNP
rs915415943 820 dbSNP
rs957177000 825 dbSNP
rs1440466518 826 dbSNP
rs1301601286 828 dbSNP
rs2361121 829 dbSNP
rs921312889 830 dbSNP
rs1182255352 835 dbSNP
rs1462976236 852 dbSNP
rs1244080299 867 dbSNP
rs915379086 868 dbSNP
rs1445429180 869 dbSNP
rs879321369 875 dbSNP
rs1294881672 879 dbSNP
rs934017375 880 dbSNP
rs1051084328 888 dbSNP
rs946891028 892 dbSNP
rs1312895326 911 dbSNP
rs911839952 912 dbSNP
rs1306297111 920 dbSNP
rs1383297777 921 dbSNP
rs192841561 925 dbSNP
rs545796114 926 dbSNP
rs1288001333 927 dbSNP
rs1259123935 934 dbSNP
rs1428227115 944 dbSNP
rs57553940 949 dbSNP
rs1036257851 951 dbSNP
rs1423492879 953 dbSNP
rs185200644 954 dbSNP
rs1254537992 959 dbSNP
rs937128802 964 dbSNP
rs1478139224 971 dbSNP
rs1057196508 972 dbSNP
rs1186235967 976 dbSNP
rs547926508 977 dbSNP
rs1185454751 978 dbSNP
rs1416725087 984 dbSNP
rs1244122013 990 dbSNP
rs567805159 993 dbSNP
rs1044832641 994 dbSNP
rs895516217 995 dbSNP
rs1491538875 998 dbSNP
rs981835532 998 dbSNP
rs11297071 999 dbSNP
rs1230163651 999 dbSNP
rs1363207901 999 dbSNP
rs1380032510 999 dbSNP
rs1403903086 999 dbSNP
rs1491305624 999 dbSNP
rs58246444 999 dbSNP
rs869199642 999 dbSNP
rs869285926 999 dbSNP
rs1304366364 1016 dbSNP
rs1427127136 1016 dbSNP
rs1171232100 1017 dbSNP
rs527492363 1019 dbSNP
rs1417068181 1023 dbSNP
rs1459745052 1024 dbSNP
rs1170357456 1025 dbSNP
rs1408614044 1032 dbSNP
rs1422032138 1033 dbSNP
rs1327639946 1041 dbSNP
rs1480194332 1044 dbSNP
rs994455793 1046 dbSNP
rs1351854911 1057 dbSNP
rs1437402182 1060 dbSNP
rs1047016230 1061 dbSNP
rs1034631373 1065 dbSNP
rs1250727874 1070 dbSNP
rs770114760 1072 dbSNP
rs1005402954 1075 dbSNP
rs1018149881 1079 dbSNP
rs1222533301 1081 dbSNP
rs899900707 1089 dbSNP
rs998320491 1091 dbSNP
rs1284790658 1093 dbSNP
rs1359881315 1097 dbSNP
rs3761061 1100 dbSNP
rs956740693 1107 dbSNP
rs988761934 1109 dbSNP
rs1279458648 1111 dbSNP
rs1356645107 1118 dbSNP
rs1171763420 1132 dbSNP
rs1334732415 1138 dbSNP
rs763238655 1139 dbSNP
rs921381282 1152 dbSNP
rs776326783 1157 dbSNP
rs955427056 1160 dbSNP
rs767784454 1164 dbSNP
rs1175446188 1166 dbSNP
rs1264663386 1166 dbSNP
rs368538869 1166 dbSNP
rs986821369 1166 dbSNP
rs968297815 1168 dbSNP
rs908554313 1169 dbSNP
rs1214550937 1172 dbSNP
rs141791543 1174 dbSNP
rs926831953 1181 dbSNP
rs937077431 1185 dbSNP
rs539386458 1187 dbSNP
rs992597661 1207 dbSNP
rs1376237046 1210 dbSNP
rs1332621210 1215 dbSNP
rs750781960 1215 dbSNP
rs577832558 1233 dbSNP
rs1256775562 1236 dbSNP
rs1404330960 1247 dbSNP
rs1338967460 1253 dbSNP
rs1466711620 1262 dbSNP
rs556402636 1263 dbSNP
rs929676570 1265 dbSNP
rs1156945060 1266 dbSNP
rs1420944371 1267 dbSNP
rs150137393 1267 dbSNP
rs1166864473 1268 dbSNP
rs1182880828 1272 dbSNP
rs538230960 1276 dbSNP
rs1459853151 1283 dbSNP
rs1244702143 1292 dbSNP
rs930512308 1305 dbSNP
rs1414164285 1307 dbSNP
rs1485307370 1309 dbSNP
rs1046986361 1310 dbSNP
rs888352815 1311 dbSNP
rs555112045 1312 dbSNP
rs1316950674 1313 dbSNP
rs138614078 1320 dbSNP
rs1381087425 1321 dbSNP
rs1317531811 1323 dbSNP
rs1039555091 1324 dbSNP
rs1384602038 1327 dbSNP
rs904975571 1330 dbSNP
rs1343648247 1334 dbSNP
rs1455449000 1352 dbSNP
rs1361222110 1355 dbSNP
rs1401967713 1356 dbSNP
rs1442626789 1364 dbSNP
rs1386874178 1367 dbSNP
rs1188067183 1372 dbSNP
rs1427698854 1380 dbSNP
rs1298862486 1382 dbSNP
rs1259277550 1390 dbSNP
rs1206500157 1393 dbSNP
rs899700953 1394 dbSNP
rs540853179 1403 dbSNP
rs1029751683 1405 dbSNP
rs1246073463 1411 dbSNP
rs892440169 1413 dbSNP
rs1009554983 1420 dbSNP
rs1022273561 1423 dbSNP
rs1326181617 1425 dbSNP
rs771461238 1428 dbSNP
rs1384089923 1434 dbSNP
rs1341213897 1436 dbSNP
rs1302563268 1437 dbSNP
rs1422807113 1451 dbSNP
rs1223566764 1456 dbSNP
rs1163736496 1460 dbSNP
rs1281793476 1460 dbSNP
rs1355371332 1463 dbSNP
rs981021739 1466 dbSNP
rs377421617 1473 dbSNP
rs567758312 1475 dbSNP
rs960906920 1476 dbSNP
rs1216727790 1479 dbSNP
rs1194914740 1481 dbSNP
rs1477906921 1485 dbSNP
rs992963777 1487 dbSNP
rs1256140490 1489 dbSNP
rs904094922 1490 dbSNP
rs1490697123 1492 dbSNP
rs1292692208 1493 dbSNP
rs997043936 1500 dbSNP
rs369168236 1506 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 125919.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000321545.4 | 3UTR | UUUAAAAAAAUGUUUCACCAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
Click to see details
77 hsa-miR-642b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT082888 ZNF543 zinc finger protein 543 2 2
MIRT108294 BHLHB9 basic helix-loop-helix family member b9 2 2
MIRT348737 ZNF350 zinc finger protein 350 2 2
MIRT381384 EXOG exo/endonuclease G 2 2
MIRT452245 TRAM1 translocation associated membrane protein 1 2 2
MIRT459262 ADRBK1 G protein-coupled receptor kinase 2 2 2
MIRT468117 SH3PXD2A SH3 and PX domains 2A 2 2
MIRT468402 SETD3 SET domain containing 3 2 2
MIRT469079 RNF168 ring finger protein 168 2 2
MIRT471690 OXR1 oxidation resistance 1 2 2
MIRT477353 EOGT EGF domain specific O-linked N-acetylglucosamine transferase 2 4
MIRT479600 CDC25B cell division cycle 25B 2 2
MIRT482377 AFF4 AF4/FMR2 family member 4 2 4
MIRT484029 LARP4B La ribonucleoprotein domain family member 4B 2 2
MIRT490988 USP22 ubiquitin specific peptidase 22 2 2
MIRT493250 MEF2D myocyte enhancer factor 2D 2 2
MIRT493850 FOXN3 forkhead box N3 2 4
MIRT496086 C17orf85 nuclear cap binding subunit 3 2 2
MIRT500630 TXNIP thioredoxin interacting protein 2 2
MIRT501048 SMEK1 protein phosphatase 4 regulatory subunit 3A 2 2
MIRT525186 ZNF257 zinc finger protein 257 2 4
MIRT534875 QSER1 glutamine and serine rich 1 2 2
MIRT539336 AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 2 2
MIRT553814 SYNCRIP synaptotagmin binding cytoplasmic RNA interacting protein 2 2
MIRT555959 NRAS NRAS proto-oncogene, GTPase 2 2
MIRT556289 MAP3K5 mitogen-activated protein kinase kinase kinase 5 2 2
MIRT561212 ZSWIM1 zinc finger SWIM-type containing 1 2 2
MIRT567328 HMGB1 high mobility group box 1 2 2
MIRT572385 LRRC6 leucine rich repeat containing 6 2 2
MIRT575529 Map4 microtubule-associated protein 4 2 2
MIRT575684 Map1b microtubule-associated protein 1B 2 2
MIRT576828 Tgfbr3 transforming growth factor, beta receptor III 2 2
MIRT576953 Pigs phosphatidylinositol glycan anchor biosynthesis, class S 2 3
MIRT608316 SYK spleen associated tyrosine kinase 2 4
MIRT609794 PINX1 PIN2/TERF1 interacting telomerase inhibitor 1 2 2
MIRT609991 PIGS phosphatidylinositol glycan anchor biosynthesis class S 2 3
MIRT611381 PNMAL1 paraneoplastic Ma antigen family member 8A 2 4
MIRT613566 YY2 YY2 transcription factor 2 2
MIRT614612 MVK mevalonate kinase 2 2
MIRT615497 MPP2 membrane palmitoylated protein 2 2 2
MIRT616941 OTUD7A OTU deubiquitinase 7A 2 2
MIRT617576 NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 2 2
MIRT618214 SPTLC3 serine palmitoyltransferase long chain base subunit 3 2 4
MIRT619885 ABHD17B abhydrolase domain containing 17B 2 2
MIRT620401 MYO1H myosin IH 2 2
MIRT620517 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT622166 SMYD1 SET and MYND domain containing 1 2 2
MIRT623195 MTX3 metaxin 3 2 2
MIRT623440 KIAA0408 KIAA0408 2 4
MIRT624837 ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 2 2
MIRT625706 SHROOM1 shroom family member 1 2 2
MIRT628159 HIP1 huntingtin interacting protein 1 2 2
MIRT629496 SGIP1 SH3 domain GRB2 like endophilin interacting protein 1 2 2
MIRT630240 SOGA3 SOGA family member 3 2 4
MIRT630521 BAZ2A bromodomain adjacent to zinc finger domain 2A 2 4
MIRT635676 COX18 COX18, cytochrome c oxidase assembly factor 2 4
MIRT637820 CACNA1B calcium voltage-gated channel subunit alpha1 B 2 2
MIRT637943 SIGLEC9 sialic acid binding Ig like lectin 9 2 2
MIRT640490 EXOC5 exocyst complex component 5 2 2
MIRT642722 ATXN3 ataxin 3 2 2
MIRT649153 LRTM1 leucine rich repeats and transmembrane domains 1 2 2
MIRT649610 ITPKC inositol-trisphosphate 3-kinase C 2 2
MIRT661016 ABCA12 ATP binding cassette subfamily A member 12 2 2
MIRT661055 RPL18A ribosomal protein L18a 2 2
MIRT684041 FOLR1 folate receptor 1 2 2
MIRT691014 CRTC3 CREB regulated transcription coactivator 3 2 2
MIRT698908 SPPL2A signal peptide peptidase like 2A 2 2
MIRT700981 PDE4D phosphodiesterase 4D 2 2
MIRT701722 MTMR12 myotubularin related protein 12 2 2
MIRT702724 INSIG1 insulin induced gene 1 2 2
MIRT705057 C5orf15 chromosome 5 open reading frame 15 2 2
MIRT705216 BRWD1 bromodomain and WD repeat domain containing 1 2 2
MIRT706088 HNRNPU heterogeneous nuclear ribonucleoprotein U 2 2
MIRT709458 KRTAP19-1 keratin associated protein 19-1 2 2
MIRT711396 RANBP2 RAN binding protein 2 2 2
MIRT720573 SDHAF2 succinate dehydrogenase complex assembly factor 2 2 2
MIRT725366 MTF2 metal response element binding transcription factor 2 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-642b-3p Platinum-based doublet chemotherapy sensitive High Lung Adenocarcinoma tissue
hsa-miR-642b-3p Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-642b-3p Imatinib 5291 NSC743414 approved sensitive High Gastrointestinal Stromal Tumor cell line (882R-NC, 882R-OE, 882R-KD)
hsa-miR-642b-3p Sunitinib 5329102 NSC750690 approved resistant Low Renal Cell Cancer cell line (ACHN, RCC23)
hsa-miR-642b-3p Paclitaxel 36314 NSC125973 approved sensitive High Ovarian Cancer cell line (HEYA8)
hsa-miR-642b-3p Fluorouracil 3385 NSC19893 approved resistant High Colorectal Cancer cell line (HT-29)
hsa-miR-642b-3p Platinum 23939 sensitive High High-Grade Serous Ovarian Cancer tissue
hsa-miR-642b-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-642b-3p Platinum-based doublet chemotherapy sensitive tissue (lung adenocarcinoma)
hsa-miR-642b-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-642b-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM16)
hsa-miR-642b-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-642b-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (OVSAHO)

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