miRTarBase - #MIRT083941


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pre-miRNA Information
pre-miRNA hsa-mir-548t   
Genomic Coordinates chr4: 173268160 - 173268233
Description Homo sapiens miR-548t stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-548t-3p
Sequence 46| AAAAACCACAAUUACUUUUGCACCA |70
Evidence Not_experimental
Experiments
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 2 4 + 173268206 29233923 MiREDiBase
A-to-I 3 4 + 173268207 29233923 MiREDiBase
A-to-I 4 4 + 173268208 29233923 MiREDiBase
A-to-I 10 4 + 173268214 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs73872515 5 dbSNP
rs1426966747 6 dbSNP
rs1158401109 21 dbSNP
rs943938928 24 dbSNP
Putative Targets

Gene Information
Gene Symbol TFAP2C   
Synonyms AP2-GAMMA, ERF1, TFAP2G, hAP-2g
Description transcription factor AP-2 gamma
Transcript NM_003222   
Expression
Putative miRNA Targets on TFAP2C
3'UTR of TFAP2C
(miRNA target sites are highlighted)		 
>TFAP2C|NM_003222|3'UTR
   1 AATTGGAACGAAGAAAGGTTAGGAGAGTAGGGAAGGAACAGGACTGCAAAAATCCTTCTCCACCGCACAGACTGGGAACC
  81 CCTCCTGGCCTGGGGGAAGAGTTTGTTACCTACCTTACTATTTAAAGAGCCTTCACTGGTTCTGCATCACCCGCCCCTGG
 161 ACTTCTTAGTTGTTTCTCTAGCGCTGAGCTATCTCCTAACTTTGGACCTATTATCAGAAGGTGACAAGTACTGGCTCTTT
 241 ATTCATTAAGCTTTTTTTTTTTGAACCCCATTCTTTCCTTCTCTGAAAGTGGTGCTATAAGTTTTAGAATCTTTTAAATA
 321 CATTCCCTGGGCCAACAGACCCACACACTTAGCCATTGAAATGTCAAATTGATGTGCCCTAGATCAACAGATCAACAATA
 401 CCTTTTTTTTCAGTGTTAAGGTAATGGTTGGTTTTTGTGTCCGCTAAATATTTACCTTGAAAAAAAGAAAAGTGTGTATC
 481 TAGCTTCTTCAGAGATCAAGTCCTCTGGTAGGAGGCAAAGGTTCTATCTGCTTAGCAACTAGTTAATAAGTGGTATCTGA
 561 CACACTCTAAACCCCGTGTTCAAACGGGGGCCTTCTGGTTTTAGGAAACTTGTAGAAACGAAGCCTGCTGATTGATTTTT
 641 TTCTCCTTTTTTTTTTTTTTTTTTTTTAACTTTGAAAGTTAACTCTTCAAATGGGAGACTCTTTGAAATGACATGTTCCT
 721 TTAAGGTACTGAAGCTTTATTTGCATATTTATTTCAGATGTTTCGAGTAAACTTGAAAAGGGTAGGCACGAAGCAATTTG
 801 TTGCTGCTTGTCACCCCCAAGTCCCCGTGGAGGTTCTGTATTTTAAGAAACAGTGCGTTGAGTGTACAGATTTTATTTAT
 881 GCGTAATTTAATGGGGTCTGTAAATACTGGTGCACTTCTTACGACTTTTTTGAGACATGGGATCCAATTTTAATATTAAC
 961 TTTTAATGGTGATGGGGTAATCTATAACACATCATAAGGTTTTATTCATATATATACAGGGTATTAAGAATTAAGAGGAT
1041 GCTGGGCTCTGTTCTTGGCTTGGAAGATTCTATTTAATTGAAACTCTCTGTTCAGAAAGCAATAACTTTGTCTCGTTCCT
1121 GTTGGGCTGAACCCTAAGGTGAGTGTGCAGTACAGTGTGTGTGGGTGAAATGGAGATTTGGAATTGAACTCTCTGCCTGT
1201 AAATGTTCCCCAAATAATTGTTGTGTGTATGATACGTGTATAATAAAAGTATTCTTGTTAGAATCTGAAAAAAAAAAAAA
1281 AAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' acCACGUUUUCAUUAAC-ACCAAAAa 5'
            |||: ||:||||| | ||||||| 
Target 5' caGTGTTAAGGTAATGGTTGGTTTTt 3'
 411 - 436 183.00 -17.40
2 
miRNA  3' acCACGUUUUCAUU---AACACCAAAAa 5'
            || |||| | ::   || ||||||| 
Target 5' gtGTTCAAACGGGGGCCTTCTGGTTTTa 3'
 576 - 603 163.00 -8.90
3 
miRNA  3' accaCGUU--UUCAUUA-ACACCAAAaa 5'
              ||||  |: ||||  ||||| |  
Target 5' cttaGCAACTAGTTAATAAGTGGTATct 3'
 531 - 558 115.00 -7.96
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30453654 9 COSMIC
COSN30128313 32 COSMIC
COSN30131385 42 COSMIC
COSN30495009 54 COSMIC
COSN30479025 55 COSMIC
COSN30593419 60 COSMIC
COSN20079804 65 COSMIC
COSN30675573 73 COSMIC
COSN31518539 154 COSMIC
COSN17037535 167 COSMIC
COSN30141203 187 COSMIC
COSN8611156 228 COSMIC
COSN30161182 264 COSMIC
COSN31547785 499 COSMIC
COSN26569918 568 COSMIC
COSN30176243 582 COSMIC
COSN27638332 610 COSMIC
COSN31539964 620 COSMIC
COSN20116593 668 COSMIC
COSN31484983 675 COSMIC
COSN2483141 710 COSMIC
COSN8611157 745 COSMIC
COSN16165411 759 COSMIC
COSN31596510 903 COSMIC
COSN31579046 932 COSMIC
COSN31480257 933 COSMIC
COSN5975025 971 COSMIC
COSN30176256 1008 COSMIC
COSN9144229 1037 COSMIC
COSN8001432 1116 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs192275203 9 dbSNP
rs182584272 10 dbSNP
rs1226320564 11 dbSNP
rs758220246 11 dbSNP
rs780029040 13 dbSNP
rs1720 14 dbSNP
rs1299753816 15 dbSNP
rs1260942637 19 dbSNP
rs555033312 28 dbSNP
rs775989958 29 dbSNP
rs1331935495 32 dbSNP
rs560333842 36 dbSNP
rs1006585551 37 dbSNP
rs1468755351 40 dbSNP
rs1195363065 44 dbSNP
rs1248408244 47 dbSNP
rs1427283752 58 dbSNP
rs532632092 58 dbSNP
rs1443604304 65 dbSNP
rs1184813442 66 dbSNP
rs1236141438 70 dbSNP
rs1190018341 74 dbSNP
rs1443318047 79 dbSNP
rs1016751097 90 dbSNP
rs898322603 91 dbSNP
rs1021223946 93 dbSNP
rs1344415262 96 dbSNP
rs1183979477 109 dbSNP
rs749713518 112 dbSNP
rs552402336 115 dbSNP
rs1048520 119 dbSNP
rs993933526 131 dbSNP
rs1026000875 132 dbSNP
rs971300475 135 dbSNP
rs1452144008 145 dbSNP
rs112123037 147 dbSNP
rs967020119 151 dbSNP
rs977165237 153 dbSNP
rs568990583 154 dbSNP
rs944890937 157 dbSNP
rs1371939996 158 dbSNP
rs1168654339 159 dbSNP
rs1405340600 161 dbSNP
rs1412309574 163 dbSNP
rs1165460631 164 dbSNP
rs1473339771 168 dbSNP
rs982528858 171 dbSNP
rs1180377396 175 dbSNP
rs976679602 176 dbSNP
rs922165006 183 dbSNP
rs538057418 184 dbSNP
rs915439516 185 dbSNP
rs1049357808 187 dbSNP
rs756050991 192 dbSNP
rs548468806 194 dbSNP
rs1287481581 204 dbSNP
rs1226246286 207 dbSNP
rs1290499764 211 dbSNP
rs1351922017 216 dbSNP
rs568344053 217 dbSNP
rs940692475 226 dbSNP
rs1435163665 233 dbSNP
rs1347555533 235 dbSNP
rs2870753 244 dbSNP
rs1326118981 245 dbSNP
rs2870754 248 dbSNP
rs1036447882 252 dbSNP
rs112295160 252 dbSNP
rs1462423173 252 dbSNP
rs1333737541 255 dbSNP
rs924188648 256 dbSNP
rs1238104871 263 dbSNP
rs1413014722 263 dbSNP
rs1190778274 264 dbSNP
rs934254784 267 dbSNP
rs780008992 270 dbSNP
rs534106984 271 dbSNP
rs745966633 272 dbSNP
rs1278982128 274 dbSNP
rs1468845975 275 dbSNP
rs1483128014 278 dbSNP
rs1267315212 282 dbSNP
rs1206551526 291 dbSNP
rs1183866434 296 dbSNP
rs553725054 298 dbSNP
rs1248024986 299 dbSNP
rs1417660826 302 dbSNP
rs1218212388 316 dbSNP
rs1002698938 323 dbSNP
rs1034119571 325 dbSNP
rs1442347218 326 dbSNP
rs576803129 332 dbSNP
rs539478139 333 dbSNP
rs1011410029 342 dbSNP
rs1319084654 343 dbSNP
rs942483941 349 dbSNP
rs1346097747 351 dbSNP
rs1038099017 353 dbSNP
rs555988383 357 dbSNP
rs1172380504 368 dbSNP
rs1427420185 380 dbSNP
rs1374903422 381 dbSNP
rs898227818 388 dbSNP
rs1206681459 392 dbSNP
rs1466094455 400 dbSNP
rs1209061389 403 dbSNP
rs1280777440 403 dbSNP
rs1310051943 404 dbSNP
rs1280179806 405 dbSNP
rs994409938 413 dbSNP
rs967063189 414 dbSNP
rs1363766025 415 dbSNP
rs1296061040 416 dbSNP
rs372272136 428 dbSNP
rs1046859818 433 dbSNP
rs1363174952 437 dbSNP
rs138048707 443 dbSNP
rs74337668 444 dbSNP
rs1174452593 446 dbSNP
rs1429204295 452 dbSNP
rs975202296 457 dbSNP
rs1430228816 459 dbSNP
rs1262228430 464 dbSNP
rs1394637197 464 dbSNP
rs1390551841 465 dbSNP
rs143521494 481 dbSNP
rs200359056 482 dbSNP
rs1012223949 483 dbSNP
rs1302639867 484 dbSNP
rs1340847949 491 dbSNP
rs1271854980 492 dbSNP
rs1022404100 497 dbSNP
rs1308571422 502 dbSNP
rs1312509065 503 dbSNP
rs953527770 518 dbSNP
rs538735394 527 dbSNP
rs1206719215 533 dbSNP
rs1409439626 536 dbSNP
rs1368860029 547 dbSNP
rs985004941 551 dbSNP
rs1463498347 556 dbSNP
rs144807818 568 dbSNP
rs1195521959 576 dbSNP
rs560499663 577 dbSNP
rs940685412 586 dbSNP
rs1268480048 587 dbSNP
rs924132716 590 dbSNP
rs35944237 593 dbSNP
rs1249045216 602 dbSNP
rs1206637111 606 dbSNP
rs1470147840 611 dbSNP
rs1192274657 612 dbSNP
rs955839906 615 dbSNP
rs1265391127 620 dbSNP
rs1036802132 621 dbSNP
rs911447413 625 dbSNP
rs1294282466 627 dbSNP
rs1228070713 629 dbSNP
rs1348826481 633 dbSNP
rs752243575 636 dbSNP
rs928667322 636 dbSNP
rs1456323745 641 dbSNP
rs1419835070 643 dbSNP
rs1050288682 644 dbSNP
rs1164230693 645 dbSNP
rs1165350436 645 dbSNP
rs1409348721 646 dbSNP
rs1472080764 646 dbSNP
rs1183470571 647 dbSNP
rs1193096429 647 dbSNP
rs1239948600 647 dbSNP
rs1299266498 647 dbSNP
rs1330665078 647 dbSNP
rs1350692567 647 dbSNP
rs34794327 647 dbSNP
rs565141146 647 dbSNP
rs57004590 647 dbSNP
rs878966659 647 dbSNP
rs879084098 647 dbSNP
rs1385057282 652 dbSNP
rs1459602093 669 dbSNP
rs1371487856 670 dbSNP
rs891112401 671 dbSNP
rs1326447834 673 dbSNP
rs1461671432 675 dbSNP
rs1294395916 677 dbSNP
rs186629660 686 dbSNP
rs1438488603 691 dbSNP
rs546248486 694 dbSNP
rs1037962985 695 dbSNP
rs191833061 700 dbSNP
rs1196095890 702 dbSNP
rs1455164222 707 dbSNP
rs919685926 712 dbSNP
rs1365866900 713 dbSNP
rs1188423773 714 dbSNP
rs746311271 733 dbSNP
rs1047377524 746 dbSNP
rs1206003409 757 dbSNP
rs531874315 765 dbSNP
rs894279306 766 dbSNP
rs745854130 780 dbSNP
rs1003229794 783 dbSNP
rs1245039696 783 dbSNP
rs1266882730 787 dbSNP
rs148562100 790 dbSNP
rs184044761 791 dbSNP
rs1252859004 795 dbSNP
rs1465751053 796 dbSNP
rs527573283 797 dbSNP
rs1400976184 802 dbSNP
rs1401093830 804 dbSNP
rs1259722497 808 dbSNP
rs1170396724 811 dbSNP
rs35845346 814 dbSNP
rs1436059280 815 dbSNP
rs1428042188 827 dbSNP
rs1165710501 828 dbSNP
rs1420329808 833 dbSNP
rs748299687 834 dbSNP
rs1194308186 839 dbSNP
rs1442161497 852 dbSNP
rs968166481 852 dbSNP
rs374605684 856 dbSNP
rs1273998746 857 dbSNP
rs1227640291 858 dbSNP
rs1337337210 859 dbSNP
rs547384561 863 dbSNP
rs1031618201 864 dbSNP
rs1339591774 871 dbSNP
rs955581210 871 dbSNP
rs1416241241 880 dbSNP
rs998516892 883 dbSNP
rs1019668265 884 dbSNP
rs1360623609 886 dbSNP
rs1428427422 901 dbSNP
rs187076642 903 dbSNP
rs973743883 904 dbSNP
rs919590735 912 dbSNP
rs879645824 923 dbSNP
rs141919939 924 dbSNP
rs982539336 926 dbSNP
rs79464696 939 dbSNP
rs1272945621 940 dbSNP
rs1275043670 948 dbSNP
rs1215022581 950 dbSNP
rs1330322356 956 dbSNP
rs1355463902 958 dbSNP
rs938546068 961 dbSNP
rs1259522751 964 dbSNP
rs1485560016 969 dbSNP
rs146111654 971 dbSNP
rs1055595565 975 dbSNP
rs894403115 978 dbSNP
rs150697977 992 dbSNP
rs984982268 996 dbSNP
rs909453309 1006 dbSNP
rs1389091712 1009 dbSNP
rs367695138 1010 dbSNP
rs999906620 1011 dbSNP
rs192966534 1012 dbSNP
rs962580466 1013 dbSNP
rs972363817 1015 dbSNP
rs1180214297 1016 dbSNP
rs1471203022 1018 dbSNP
rs928588313 1020 dbSNP
rs938704662 1028 dbSNP
rs1205207747 1041 dbSNP
rs55887137 1047 dbSNP
rs1156789856 1052 dbSNP
rs1344559763 1057 dbSNP
rs185256295 1063 dbSNP
rs574703444 1071 dbSNP
rs1271080617 1083 dbSNP
rs1314184477 1084 dbSNP
rs891166364 1094 dbSNP
rs1396195166 1100 dbSNP
rs1353100555 1107 dbSNP
rs1279613692 1115 dbSNP
rs558923104 1116 dbSNP
rs1288639050 1122 dbSNP
rs1351450370 1142 dbSNP
rs1462310621 1143 dbSNP
rs1388284764 1145 dbSNP
rs6099216 1149 dbSNP
rs1402655313 1150 dbSNP
rs73165730 1154 dbSNP
rs1190650900 1159 dbSNP
rs868804360 1160 dbSNP
rs903029315 1164 dbSNP
rs1210824616 1166 dbSNP
rs143623320 1170 dbSNP
rs999154005 1175 dbSNP
rs1040968451 1181 dbSNP
rs1251082069 1182 dbSNP
rs1026635809 1187 dbSNP
rs1468753830 1189 dbSNP
rs951091472 1190 dbSNP
rs900799631 1192 dbSNP
rs1484765104 1197 dbSNP
rs996546756 1201 dbSNP
rs982829695 1204 dbSNP
rs1252852114 1214 dbSNP
rs146779844 1236 dbSNP
rs570963061 1237 dbSNP
rs1306280393 1246 dbSNP
rs1442282879 1250 dbSNP
rs747524696 1252 dbSNP
rs1287465135 1254 dbSNP
rs1433199874 1261 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 7022.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000201031.2 | 3UTR | UUUUAUUCAUAUAUAUACAGGGUAUUAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000201031.2 | 3UTR | UUUUAUUCAUAUAUAUACAGGGUAUUAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
168 hsa-miR-548t-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT059365 ANP32E acidic nuclear phosphoprotein 32 family member E 2 2
MIRT072839 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2 6
MIRT076945 PCGF2 polycomb group ring finger 2 2 6
MIRT083941 TFAP2C transcription factor AP-2 gamma 2 2
MIRT085401 ETS2 ETS proto-oncogene 2, transcription factor 2 2
MIRT109790 KLHL15 kelch like family member 15 2 2
MIRT114046 AKAP11 A-kinase anchoring protein 11 2 10
MIRT130165 TXNIP thioredoxin interacting protein 2 6
MIRT150013 MIDN midnolin 2 2
MIRT181258 ASH1L ASH1 like histone lysine methyltransferase 2 2
MIRT205594 NCL nucleolin 2 2
MIRT222253 ACTB actin beta 2 4
MIRT245653 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 4
MIRT250947 CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 2 4
MIRT252497 NWD1 NACHT and WD repeat domain containing 1 2 2
MIRT271990 ARF1 ADP ribosylation factor 1 2 4
MIRT280804 RNF11 ring finger protein 11 2 2
MIRT293803 FEM1A fem-1 homolog A 2 2
MIRT318231 RREB1 ras responsive element binding protein 1 2 2
MIRT341455 ATP6V0B ATPase H+ transporting V0 subunit b 2 2
MIRT347413 CEBPG CCAAT/enhancer binding protein gamma 2 4
MIRT351860 PLEKHA3 pleckstrin homology domain containing A3 2 2
MIRT357983 GRPEL2 GrpE like 2, mitochondrial 2 2
MIRT377094 PPP1CB protein phosphatase 1 catalytic subunit beta 2 2
MIRT407303 IGFBP5 insulin like growth factor binding protein 5 2 2
MIRT441564 LMOD3 leiomodin 3 2 2
MIRT442364 ZC3H12C zinc finger CCCH-type containing 12C 2 2
MIRT443228 ARL5B ADP ribosylation factor like GTPase 5B 2 2
MIRT443404 HMX3 H6 family homeobox 3 2 2
MIRT446055 NR5A2 nuclear receptor subfamily 5 group A member 2 2 2
MIRT448277 ZNF652 zinc finger protein 652 2 2
MIRT450822 KCNB1 potassium voltage-gated channel subfamily B member 1 2 2
MIRT453016 CCDC115 coiled-coil domain containing 115 2 17
MIRT454463 PPP2R2B protein phosphatase 2 regulatory subunit Bbeta 2 2
MIRT456360 CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 2 2
MIRT460007 DNALI1 dynein axonemal light intermediate chain 1 2 2
MIRT463154 ZNF385A zinc finger protein 385A 2 6
MIRT463766 YPEL2 yippee like 2 2 2
MIRT468310 SFT2D2 SFT2 domain containing 2 2 2
MIRT470668 POLR2D RNA polymerase II subunit D 2 4
MIRT478517 CTTN cortactin 2 2
MIRT480507 C11orf57 chromosome 11 open reading frame 57 2 2
MIRT484718 INHBA inhibin beta A subunit 2 12
MIRT485494 HMGN2 high mobility group nucleosomal binding domain 2 2 2
MIRT487302 SLC38A9 solute carrier family 38 member 9 2 2
MIRT487771 ANKEF1 ankyrin repeat and EF-hand domain containing 1 2 16
MIRT491876 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT494304 CEP120 centrosomal protein 120 2 2
MIRT495396 TRIM24 tripartite motif containing 24 2 2
MIRT495646 CDK1 cyclin dependent kinase 1 2 2
MIRT496665 TMEM237 transmembrane protein 237 2 2
MIRT496837 ZNF460 zinc finger protein 460 2 2
MIRT498638 CHD4 chromodomain helicase DNA binding protein 4 2 10
MIRT503928 FBXL13 F-box and leucine rich repeat protein 13 2 4
MIRT506063 PPP2R2A protein phosphatase 2 regulatory subunit Balpha 2 2
MIRT506582 MIER3 MIER family member 3 2 4
MIRT506606 MAT2A methionine adenosyltransferase 2A 2 4
MIRT506844 KIF23 kinesin family member 23 2 6
MIRT508536 RPP14 ribonuclease P/MRP subunit p14 2 4
MIRT509669 ZNF354B zinc finger protein 354B 2 10
MIRT511170 MBNL3 muscleblind like splicing regulator 3 2 6
MIRT512147 COX6B1 cytochrome c oxidase subunit 6B1 2 2
MIRT512831 ID4 inhibitor of DNA binding 4, HLH protein 2 6
MIRT514558 XRCC3 X-ray repair cross complementing 3 2 4
MIRT515856 AJAP1 adherens junctions associated protein 1 2 4
MIRT521848 PNISR PNN interacting serine and arginine rich protein 2 4
MIRT525364 SYNM synemin 2 2
MIRT527120 ARHGAP15 Rho GTPase activating protein 15 2 2
MIRT527271 FBLN2 fibulin 2 2 2
MIRT527439 COL4A3 collagen type IV alpha 3 chain 2 2
MIRT527658 CD300E CD300e molecule 2 2
MIRT528334 TBC1D22B TBC1 domain family member 22B 2 2
MIRT529033 EXOC8 exocyst complex component 8 2 2
MIRT529321 PDE5A phosphodiesterase 5A 2 2
MIRT529677 TRPV2 transient receptor potential cation channel subfamily V member 2 2 2
MIRT529846 SMTN smoothelin 2 2
MIRT530385 ZNF431 zinc finger protein 431 2 2
MIRT530913 GPR85 G protein-coupled receptor 85 2 2
MIRT531794 KDR kinase insert domain receptor 2 2
MIRT532246 KLF2 Kruppel like factor 2 2 4
MIRT532658 CBX7 chromobox 7 2 2
MIRT533630 TMX3 thioredoxin related transmembrane protein 3 2 2
MIRT534811 RAB33B RAB33B, member RAS oncogene family 2 2
MIRT534975 PSD3 pleckstrin and Sec7 domain containing 3 2 2
MIRT536588 ITPKB inositol-trisphosphate 3-kinase B 2 2
MIRT536779 HNRNPD heterogeneous nuclear ribonucleoprotein D 2 2
MIRT538764 CABLES1 Cdk5 and Abl enzyme substrate 1 2 2
MIRT539294 ANGEL2 angel homolog 2 2 2
MIRT539621 SHISA9 shisa family member 9 2 2
MIRT539651 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 2 2
MIRT540347 OPHN1 oligophrenin 1 2 2
MIRT540413 PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 2 2
MIRT541396 CDC27 cell division cycle 27 2 2
MIRT542916 HSBP1 heat shock factor binding protein 1 2 2
MIRT544710 EIF5A eukaryotic translation initiation factor 5A 2 4
MIRT544998 MFF mitochondrial fission factor 2 4
MIRT553289 TSPAN3 tetraspanin 3 2 2
MIRT553455 TNRC6C trinucleotide repeat containing 6C 2 2
MIRT553782 TAF13 TATA-box binding protein associated factor 13 2 2
MIRT554656 ROBO1 roundabout guidance receptor 1 2 2
MIRT555104 PURB purine rich element binding protein B 2 2
MIRT557235 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT560861 GAL3ST3 galactose-3-O-sulfotransferase 3 2 2
MIRT561545 SON SON DNA binding protein 2 2
MIRT561554 SLMO2 PRELI domain containing 3B 2 2
MIRT563764 ZNF678 zinc finger protein 678 2 2
MIRT565653 SIX4 SIX homeobox 4 2 2
MIRT568080 CELF2 CUGBP Elav-like family member 2 2 2
MIRT568759 MYBL1 MYB proto-oncogene like 1 2 2
MIRT569078 CADM2 cell adhesion molecule 2 2 2
MIRT569509 THYN1 thymocyte nuclear protein 1 2 2
MIRT571268 CDKN2AIP CDKN2A interacting protein 2 2
MIRT571809 PHF19 PHD finger protein 19 2 2
MIRT572554 DKK3 dickkopf WNT signaling pathway inhibitor 3 2 2
MIRT573782 SLC24A4 solute carrier family 24 member 4 2 4
MIRT576441 Ccdc115 coiled-coil domain containing 115 2 10
MIRT576712 Slc30a3 solute carrier family 30 (zinc transporter), member 3 2 3
MIRT608377 PIWIL2 piwi like RNA-mediated gene silencing 2 2 2
MIRT608484 NKTR natural killer cell triggering receptor 2 6
MIRT610186 FAM49A family with sequence similarity 49 member A 2 2
MIRT611631 EDIL3 EGF like repeats and discoidin domains 3 2 2
MIRT613534 TRA2B transformer 2 beta homolog 2 2
MIRT616221 PTPN11 protein tyrosine phosphatase, non-receptor type 11 2 2
MIRT622370 SALL1 spalt like transcription factor 1 2 2
MIRT624371 CDK12 cyclin dependent kinase 12 2 2
MIRT624995 ZNF665 zinc finger protein 665 2 4
MIRT626875 AP3B1 adaptor related protein complex 3 beta 1 subunit 2 2
MIRT627737 RAP2B RAP2B, member of RAS oncogene family 2 4
MIRT628490 ADAT2 adenosine deaminase, tRNA specific 2 2 2
MIRT633647 PLEKHG7 pleckstrin homology and RhoGEF domain containing G7 2 4
MIRT634028 SLC30A3 solute carrier family 30 member 3 2 3
MIRT635923 GLTSCR2 NOP53 ribosome biogenesis factor 2 2
MIRT638287 SERBP1 SERPINE1 mRNA binding protein 1 2 2
MIRT641959 RNF115 ring finger protein 115 2 2
MIRT643573 CTNNA3 catenin alpha 3 2 2
MIRT645180 NOL9 nucleolar protein 9 2 4
MIRT647497 ZNF639 zinc finger protein 639 2 2
MIRT647682 PCK1 phosphoenolpyruvate carboxykinase 1 2 2
MIRT648422 MYOZ3 myozenin 3 2 2
MIRT650113 ZCCHC9 zinc finger CCHC-type containing 9 2 2
MIRT651076 ZNF518B zinc finger protein 518B 2 4
MIRT651415 ZADH2 zinc binding alcohol dehydrogenase domain containing 2 2 2
MIRT651456 XKR4 XK related 4 2 2
MIRT653619 SLC30A4 solute carrier family 30 member 4 2 2
MIRT653637 SLC30A1 solute carrier family 30 member 1 2 2
MIRT654896 POU2F1 POU class 2 homeobox 1 2 2
MIRT656483 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 2
MIRT658016 GABRA4 gamma-aminobutyric acid type A receptor alpha4 subunit 2 2
MIRT658041 FZD10 frizzled class receptor 10 2 2
MIRT660093 BTBD3 BTB domain containing 3 2 2
MIRT663923 MAGEF1 MAGE family member F1 2 2
MIRT665882 TGIF2 TGFB induced factor homeobox 2 2 2
MIRT669051 CEP128 centrosomal protein 128 2 2
MIRT669711 AAGAB alpha and gamma adaptin binding protein 2 2
MIRT686812 SNX2 sorting nexin 2 2 4
MIRT689883 SOD2 superoxide dismutase 2 2 2
MIRT693274 GLRX2 glutaredoxin 2 2 4
MIRT697056 BCAR1 BCAR1, Cas family scaffolding protein 2 2
MIRT703297 GID4 GID complex subunit 4 homolog 2 2
MIRT704087 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 2 2
MIRT707719 CDC6 cell division cycle 6 2 2
MIRT708136 GK5 glycerol kinase 5 (putative) 2 2
MIRT709212 KLHL30 kelch like family member 30 2 2
MIRT710062 RWDD2A RWD domain containing 2A 2 2
MIRT712770 POU6F2 POU class 6 homeobox 2 2 2
MIRT715073 TMTC1 transmembrane and tetratricopeptide repeat containing 1 2 2
MIRT715387 TADA3 transcriptional adaptor 3 2 2
MIRT717712 NCKAP1 NCK associated protein 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-548t Paclitaxel 36314 NSC125973 approved sensitive cell line (W1)
hsa-mir-548t Cisplatin 5460033 NSC119875 approved sensitive cell line (W1)
hsa-mir-548t Doxorubicin 31703 NSC123127 approved sensitive cell line (W1)
hsa-mir-548t Topotecan 60699 NSC609699 approved sensitive cell line (W1)
hsa-mir-548t Vincristine 5978 approved sensitive cell line (W1)
hsa-miR-548t-3p Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer cell line (SW480, HCT-116)
hsa-miR-548t-3p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-548t-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)

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