miRTarBase - #MIRT085309


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pre-miRNA Information
pre-miRNA hsa-mir-367   
Genomic Coordinates chr4: 112647874 - 112647941
Synonyms MIRN367, hsa-mir-367, MIR367
Description Homo sapiens miR-367 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-367-3p
Sequence 44| AAUUGCACUUUAGCAAUGGUGA |65
Evidence Experimental
Experiments Cloned
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN24411246 17 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs535597757 1 dbSNP
rs1013348949 11 dbSNP
rs896333735 12 dbSNP
rs751269136 14 dbSNP
rs1163501507 16 dbSNP
rs757092597 21 dbSNP
Putative Targets

Gene Information
Gene Symbol UBXN4   
Synonyms UBXD2, UBXDC1, erasin
Description UBX domain protein 4
Transcript NM_014607   
Expression
Putative miRNA Targets on UBXN4
3'UTR of UBXN4
(miRNA target sites are highlighted)		 
>UBXN4|NM_014607|3'UTR
   1 TGTGACAAGTATAATATGTGCAATAATCATTGTTTCTCTTATGATTTAATTCAACTAAAATTCTACTGGAGAAGTGGGAC
  81 TGCTTTATATTTTCCAACTGGTCTATAAAATGTCTCTTTATTCCTGCTTAGTGGGTGTGGGTTGAAGGTGTTTAACTCAG
 161 AAAAGTAAAGACAGGAAATAACTCTCTGCTAGGTCCTTGCTTATATGGCAACCACTGCTAGAACCCTAAAAGAACCAAAA
 241 ATCTGCCACAGCCTGCCTCCATCAGCTTCTTATTTAGTATTTCATATGCCCATTAGCCCTATGCTTCAGATGACACGTTT
 321 TGTTTAGAGCTACTTTGCTCCAAGACTCTTAAGCCCAAAGTAACTGGTATGTCACTGAGTAACTTGACTCGGTGTCAGAG
 401 CATTTTAACTAGCCACTCAGATGAGAATTTATGTTTAACTTCTCTTTTTACTCATCAGCTGCAAGCAAAATCTTGTAGTT
 481 TTTAATCTTAAACACTGAATAAAAAAACTTTCCCCTAAATTGGAATGATCTTAGTTTTGCTTTGAGTTTTGTTATCTAGC
 561 ATCTTTTTGTTGCACAGGGCTCTATTGAGGTCCTATGTCTCTGATTTTTTTTTTTCCCCAGTATTGCCCTGGAGCTGTCT
 641 CTGGAAAGTAGCTGGCGAGGTTACCTTAACTATCACTGAAGAAAGAAATTTTCTGACACACTGATGGCATGTGACTTGTC
 721 TCCTAAGTCAGTGAGGCATCACTTTGTTTGCATAAAGTATACGGTTTGTTAAGGCCTTTGTTCTTGTGAGATGCAAAACA
 801 GCTGCTAGTCTGCAACCTAGTTTTCCCTCTCACCTTTAACTGACGTTTTGTCCTCAATAATTACACAAGGACCTAGAGTA
 881 CCTATAGGACAAAAAGTATAGAATAAAAATATGCCTTTAGTCATTTGGTTTTTCTTAAAAAGTTGAGATTCTTAATCTGA
 961 CTTACATGTTACTTTATCCGTATGTCTTTGTTAGTGGAGACCGCTAAACTAATGATGTTTGAAAACAGTTCCTCTGTTTT
1041 AGATTGGAAGATAGCACTCTAGAGTGGACATACGGAAAGACTGTGACTTTATTTTGTAATGGGAGGAAGAAATTTTCTCA
1121 GAGCAAACTTTCTATTTTTTACCTGTGAAATAACAGTGACTTTTTAAAATGGTGACAGTGTTGGCAAGGAAACAGCAACA
1201 CAGGCTGCGCTGTTGGTAGGAGTGAAAACCAGTATAATTCTTCTGAAAAACATTTATCAGAAACTTAAAATATTTCATAC
1281 CGTTTGATCCAGTAGCTTCTTCTAAATCATAAATGCAGACAATGTTTAGGTAAAGACATACTCATTAAGTGTTATTTATT
1361 TTACTCAAGAACTGGAAACCAACTAAATGCCTTCTATAGAAGTAATTTTTGATGAGGAGAAATGGTACAATACTAATTAA
1441 CAACTTGGTTTAACATGTTTACTGAGCATCTGTTAAGTGTTGGGGGAAAAAGCAGCAGGATCCAGAGCTATAGGTACAGT
1521 GTGATCTCAGCTTTGCAAACACATTTTCTACATAGATAGTACTAGGTATTAATAGATATGTAAAGAAAGAAATCACACCA
1601 TTAATAATGGTAAGATTGGTTTATGTGATTTTAGTGGTATTTTTGGCACCCTTATATATGTTTTCCAAACTTTCAGCAGT
1681 GATATTATTTCCATAACTTAAAAAGTGAGTTTGAAAAAGAAAATCTCCAGCAAGCATCTCATTTAAATAAAGGTTTGTCA
1761 TCTTTAAAAATACAGCAATATGTGACTTTTTAAAAAAGCTGTCAAATAGGTGTGACCCTACTAATAATTATTAGAAATAC
1841 ATTTAAAAACATCGAGTACCTCAAGTCAGTTTGCCTTGAAAAATATCAAATATAACTCTTAGAGAAATGTACATAAAAGA
1921 ATGCTTCGTAATTTTGGAGTAGGAGGTTCCCTCCTCAATTTTGTATTTTTAAAAAGTACATGGTAAAAAAAAAAATTCAC
2001 AACAGTATATAAGGCTGTAAAATGAGAATTCTGCCCCCTCACCTCTTACCCCAGTACTATTCTCCAGAGGTAATCTATTA
2081 ACAATTTCTTATGTAATTTTCAGAAAATTTGTATGCGTATATAAGCAAATATGTAATCTTTATTTTTTAAATAAATGGGA
2161 TCATATTATATATTCTAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agUGGUAACGAU-UUCACGUUAa 5'
            || | | : | | ||||||| 
Target 5' tgACAAGTATAATATGTGCAATa 3'
 3 - 25 148.00 -6.40
2 
miRNA  3' agUGGUAACGAUUUCACGUUAa 5'
            :|:|| | || ||||::|| 
Target 5' gaGCTATAGGTACAGTGTGATc 3'
 1505 - 1526 136.00 -8.20
3 
miRNA  3' agUGGUAACGAUUUCACGUUaa 5'
            || : |||||:  |||||  
Target 5' aaACAGCTGCTAGTCTGCAAcc 3'
 796 - 817 116.00 -10.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN6210542 6 COSMIC
COSN24395129 7 COSMIC
COSN24309126 15 COSMIC
COSN30123451 16 COSMIC
COSN30136683 27 COSMIC
COSN511415 27 COSMIC
COSN27001036 42 COSMIC
COSN30475857 64 COSMIC
COSN30451132 96 COSMIC
COSN31605803 117 COSMIC
COSN9228059 160 COSMIC
COSN32065145 185 COSMIC
COSN6210543 269 COSMIC
COSN32065146 284 COSMIC
COSN8344317 345 COSMIC
COSN14986229 498 COSMIC
COSN20097182 616 COSMIC
COSN9081964 767 COSMIC
COSN21602710 1068 COSMIC
COSN7339533 1466 COSMIC
COSN7339534 1468 COSMIC
COSN17906545 1635 COSMIC
COSN30172576 1714 COSMIC
COSN31562101 1793 COSMIC
COSN31487873 1840 COSMIC
COSN9081965 1925 COSMIC
COSN20097190 1975 COSMIC
COSN31577623 2015 COSMIC
COSN31521165 2020 COSMIC
COSN31522528 2074 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs759920213 1 dbSNP
rs1466248133 9 dbSNP
rs762096740 10 dbSNP
rs772464212 15 dbSNP
rs377720171 19 dbSNP
rs761225773 21 dbSNP
rs769848105 22 dbSNP
rs764597151 24 dbSNP
rs1221905683 25 dbSNP
rs1303175710 29 dbSNP
rs773551241 30 dbSNP
rs753887108 36 dbSNP
rs987923803 37 dbSNP
rs185794991 43 dbSNP
rs369790270 46 dbSNP
rs1315557345 50 dbSNP
rs1043938898 66 dbSNP
rs1382682270 70 dbSNP
rs1313014774 75 dbSNP
rs1454609511 88 dbSNP
rs1033300114 92 dbSNP
rs1383828802 97 dbSNP
rs1387840777 98 dbSNP
rs1451850820 99 dbSNP
rs1305403621 103 dbSNP
rs1343280484 113 dbSNP
rs1338900517 117 dbSNP
rs957522744 117 dbSNP
rs1420243407 125 dbSNP
rs1384464150 128 dbSNP
rs1161169520 132 dbSNP
rs544812714 135 dbSNP
rs1256220058 138 dbSNP
rs1185612516 142 dbSNP
rs937928872 154 dbSNP
rs1056270827 183 dbSNP
rs1217733577 185 dbSNP
rs1023153020 186 dbSNP
rs971448636 189 dbSNP
rs1248776523 193 dbSNP
rs571973409 196 dbSNP
rs768411840 204 dbSNP
rs1015027580 208 dbSNP
rs1364275127 214 dbSNP
rs972390599 218 dbSNP
rs897884992 236 dbSNP
rs1161651483 237 dbSNP
rs1426438555 243 dbSNP
rs995043834 244 dbSNP
rs1224137334 249 dbSNP
rs1264906388 267 dbSNP
rs1169119404 272 dbSNP
rs930567725 274 dbSNP
rs1355613365 278 dbSNP
rs1050191721 279 dbSNP
rs1223116639 285 dbSNP
rs910405915 286 dbSNP
rs1028227726 287 dbSNP
rs953647315 290 dbSNP
rs1267172811 299 dbSNP
rs539310760 300 dbSNP
rs1487153912 302 dbSNP
rs1225245797 310 dbSNP
rs773682040 317 dbSNP
rs902841996 318 dbSNP
rs1223115836 332 dbSNP
rs934383558 334 dbSNP
rs1261948487 337 dbSNP
rs1406760099 342 dbSNP
rs1019181898 349 dbSNP
rs1297112568 349 dbSNP
rs893359730 359 dbSNP
rs868419453 361 dbSNP
rs1355750384 365 dbSNP
rs965721513 371 dbSNP
rs1013193156 375 dbSNP
rs1427704117 376 dbSNP
rs988195609 386 dbSNP
rs371140233 390 dbSNP
rs1201966402 391 dbSNP
rs1023120507 392 dbSNP
rs1165951232 393 dbSNP
rs1359040865 398 dbSNP
rs1194175952 404 dbSNP
rs747427509 409 dbSNP
rs1338154660 410 dbSNP
rs907397392 413 dbSNP
rs913681371 414 dbSNP
rs1203350555 419 dbSNP
rs1419425925 420 dbSNP
rs1289697290 422 dbSNP
rs1321657488 436 dbSNP
rs1364394425 440 dbSNP
rs1003360498 448 dbSNP
rs1331631747 452 dbSNP
rs554378978 456 dbSNP
rs946451877 464 dbSNP
rs979328836 466 dbSNP
rs926460891 467 dbSNP
rs1378560009 473 dbSNP
rs937811399 476 dbSNP
rs572525935 481 dbSNP
rs1403359802 495 dbSNP
rs1341135378 501 dbSNP
rs77543183 508 dbSNP
rs1056322458 509 dbSNP
rs1363563690 509 dbSNP
rs1293796785 512 dbSNP
rs746284714 512 dbSNP
rs1238934989 515 dbSNP
rs78711669 520 dbSNP
rs1201224210 535 dbSNP
rs191438489 535 dbSNP
rs951942674 546 dbSNP
rs80218406 553 dbSNP
rs910374668 558 dbSNP
rs944591328 563 dbSNP
rs897942689 564 dbSNP
rs924346875 567 dbSNP
rs1380155247 577 dbSNP
rs1335836109 580 dbSNP
rs1179754161 586 dbSNP
rs1396220877 592 dbSNP
rs1254880288 597 dbSNP
rs995326107 601 dbSNP
rs1422079354 603 dbSNP
rs201066570 604 dbSNP
rs1381405358 605 dbSNP
rs1442905824 605 dbSNP
rs3832057 605 dbSNP
rs397786592 605 dbSNP
rs199838500 606 dbSNP
rs1188586351 616 dbSNP
rs201275174 616 dbSNP
rs776912846 618 dbSNP
rs934413858 620 dbSNP
rs1260792800 622 dbSNP
rs889303064 624 dbSNP
rs1054098733 630 dbSNP
rs1286586021 638 dbSNP
rs1007710127 640 dbSNP
rs1356695574 645 dbSNP
rs1285445177 655 dbSNP
rs576444097 657 dbSNP
rs1019232647 658 dbSNP
rs543417547 660 dbSNP
rs564911890 663 dbSNP
rs576745232 664 dbSNP
rs1361763541 667 dbSNP
rs1303120436 694 dbSNP
rs1464790297 701 dbSNP
rs1416119992 702 dbSNP
rs907366102 703 dbSNP
rs1302410556 710 dbSNP
rs866868095 724 dbSNP
rs868640187 725 dbSNP
rs1190786181 729 dbSNP
rs527801422 736 dbSNP
rs1243467458 740 dbSNP
rs1489177895 741 dbSNP
rs759430483 743 dbSNP
rs1009269836 753 dbSNP
rs540907987 758 dbSNP
rs1291426026 763 dbSNP
rs967700372 764 dbSNP
rs1003002159 769 dbSNP
rs1307140405 777 dbSNP
rs979597772 801 dbSNP
rs1341592689 808 dbSNP
rs897207219 809 dbSNP
rs996017695 821 dbSNP
rs926346399 827 dbSNP
rs771518058 828 dbSNP
rs867929802 830 dbSNP
rs959215269 833 dbSNP
rs1424149008 837 dbSNP
rs986004612 837 dbSNP
rs182866788 845 dbSNP
rs917859216 846 dbSNP
rs1248350202 848 dbSNP
rs1221694205 851 dbSNP
rs1436774166 856 dbSNP
rs1017515240 865 dbSNP
rs1318098119 868 dbSNP
rs1318436832 882 dbSNP
rs939923294 885 dbSNP
rs1370389604 896 dbSNP
rs374405571 900 dbSNP
rs1255000440 901 dbSNP
rs1442072030 903 dbSNP
rs1036401879 911 dbSNP
rs1334129174 913 dbSNP
rs1333433111 916 dbSNP
rs975907882 920 dbSNP
rs1466349357 929 dbSNP
rs919251786 936 dbSNP
rs1175486375 942 dbSNP
rs529844106 944 dbSNP
rs1205056252 948 dbSNP
rs1426984063 952 dbSNP
rs1191763446 957 dbSNP
rs1469549433 962 dbSNP
rs777310313 966 dbSNP
rs1179895252 967 dbSNP
rs1049195000 972 dbSNP
rs1178274909 973 dbSNP
rs185935870 980 dbSNP
rs112985453 981 dbSNP
rs1279780004 996 dbSNP
rs190447425 999 dbSNP
rs530572730 1001 dbSNP
rs1044085548 1003 dbSNP
rs1430294570 1004 dbSNP
rs1335031071 1005 dbSNP
rs1450433158 1006 dbSNP
rs1471065872 1014 dbSNP
rs1007762501 1022 dbSNP
rs1040557322 1023 dbSNP
rs183394850 1025 dbSNP
rs1399640473 1027 dbSNP
rs1439824435 1033 dbSNP
rs1441399892 1034 dbSNP
rs1010236306 1035 dbSNP
rs1298624665 1035 dbSNP
rs1021172979 1041 dbSNP
rs116010172 1045 dbSNP
rs1000464306 1047 dbSNP
rs1238425443 1053 dbSNP
rs1033412820 1071 dbSNP
rs759597793 1075 dbSNP
rs991985709 1082 dbSNP
rs1241481442 1091 dbSNP
rs769780494 1092 dbSNP
rs961195114 1097 dbSNP
rs1230251311 1100 dbSNP
rs762097718 1110 dbSNP
rs1019581882 1113 dbSNP
rs973067348 1116 dbSNP
rs139461886 1131 dbSNP
rs76701251 1131 dbSNP
rs1255679593 1132 dbSNP
rs200429977 1133 dbSNP
rs1300004407 1135 dbSNP
rs930664807 1135 dbSNP
rs1031489899 1136 dbSNP
rs539369190 1142 dbSNP
rs1235066406 1145 dbSNP
rs1425191754 1149 dbSNP
rs549813216 1159 dbSNP
rs1487774711 1160 dbSNP
rs566977368 1161 dbSNP
rs1049079409 1162 dbSNP
rs550558430 1162 dbSNP
rs1265759615 1164 dbSNP
rs910675198 1170 dbSNP
rs1490312133 1171 dbSNP
rs377100533 1179 dbSNP
rs35190642 1188 dbSNP
rs1263762123 1189 dbSNP
rs547773362 1194 dbSNP
rs1322573781 1195 dbSNP
rs1295186623 1207 dbSNP
rs566304152 1209 dbSNP
rs536458280 1210 dbSNP
rs969801573 1227 dbSNP
rs1400554136 1231 dbSNP
rs1364817118 1233 dbSNP
rs1458953467 1241 dbSNP
rs1168716227 1242 dbSNP
rs1349939518 1244 dbSNP
rs1423028193 1251 dbSNP
rs1476635004 1257 dbSNP
rs1426247065 1266 dbSNP
rs979733754 1270 dbSNP
rs1410558849 1279 dbSNP
rs1194750197 1281 dbSNP
rs868572648 1282 dbSNP
rs555101068 1283 dbSNP
rs1193406125 1303 dbSNP
rs1171093131 1314 dbSNP
rs1037720556 1322 dbSNP
rs1356246054 1325 dbSNP
rs902017965 1337 dbSNP
rs931522391 1342 dbSNP
rs945535802 1344 dbSNP
rs1218972629 1346 dbSNP
rs370474295 1350 dbSNP
rs1302370595 1352 dbSNP
rs1043049831 1356 dbSNP
rs1299171865 1367 dbSNP
rs904086758 1370 dbSNP
rs1006943206 1374 dbSNP
rs1041027354 1383 dbSNP
rs901198381 1395 dbSNP
rs1000516104 1397 dbSNP
rs576153955 1398 dbSNP
rs1338218732 1401 dbSNP
rs1214690184 1402 dbSNP
rs894935385 1406 dbSNP
rs1171852536 1425 dbSNP
rs1469651566 1439 dbSNP
rs529466804 1445 dbSNP
rs1320502725 1447 dbSNP
rs1222399237 1448 dbSNP
rs1013290070 1449 dbSNP
rs1270062553 1453 dbSNP
rs955984738 1456 dbSNP
rs1490927219 1459 dbSNP
rs1238970373 1469 dbSNP
rs1011379403 1473 dbSNP
rs1024690734 1485 dbSNP
rs72972108 1488 dbSNP
rs1235405232 1491 dbSNP
rs972575831 1492 dbSNP
rs1027347279 1494 dbSNP
rs558560753 1496 dbSNP
rs576801933 1502 dbSNP
rs928310523 1508 dbSNP
rs960010728 1511 dbSNP
rs1395085390 1519 dbSNP
rs918797493 1539 dbSNP
rs973009230 1539 dbSNP
rs541361937 1540 dbSNP
rs931574818 1545 dbSNP
rs1467009823 1547 dbSNP
rs952601848 1559 dbSNP
rs763085538 1566 dbSNP
rs1188403717 1567 dbSNP
rs1411698944 1569 dbSNP
rs116317410 1578 dbSNP
rs943318159 1580 dbSNP
rs1183294105 1583 dbSNP
rs1440901618 1597 dbSNP
rs1253839094 1616 dbSNP
rs911409839 1619 dbSNP
rs1483547653 1620 dbSNP
rs1285279268 1624 dbSNP
rs574634592 1626 dbSNP
rs1041559231 1628 dbSNP
rs1309333277 1630 dbSNP
rs923356490 1634 dbSNP
rs1296084758 1637 dbSNP
rs1325542249 1649 dbSNP
rs901170190 1653 dbSNP
rs935288842 1654 dbSNP
rs541661486 1655 dbSNP
rs1336593127 1656 dbSNP
rs1396925766 1662 dbSNP
rs945558227 1669 dbSNP
rs1430995558 1683 dbSNP
rs1360267093 1685 dbSNP
rs1296933774 1687 dbSNP
rs1422058899 1696 dbSNP
rs1052453008 1707 dbSNP
rs563469926 1710 dbSNP
rs1042547556 1713 dbSNP
rs891686788 1713 dbSNP
rs1376265278 1718 dbSNP
rs1011515603 1727 dbSNP
rs1021447455 1728 dbSNP
rs1188476735 1735 dbSNP
rs751328631 1738 dbSNP
rs1262196029 1754 dbSNP
rs1245910227 1758 dbSNP
rs1214432062 1779 dbSNP
rs1489197387 1783 dbSNP
rs1286113581 1790 dbSNP
rs936919762 1793 dbSNP
rs1293078125 1807 dbSNP
rs1055262222 1808 dbSNP
rs894820825 1811 dbSNP
rs1285646568 1812 dbSNP
rs1245028804 1814 dbSNP
rs1340375004 1818 dbSNP
rs1013174593 1823 dbSNP
rs1214956832 1823 dbSNP
rs1361662249 1829 dbSNP
rs1001286750 1834 dbSNP
rs1283976336 1835 dbSNP
rs530637302 1838 dbSNP
rs1164115441 1840 dbSNP
rs1447854493 1842 dbSNP
rs1465285510 1855 dbSNP
rs879857047 1858 dbSNP
rs1235810339 1860 dbSNP
rs1472475390 1877 dbSNP
rs1478780005 1879 dbSNP
rs1035888695 1882 dbSNP
rs1182933779 1886 dbSNP
rs1198054460 1887 dbSNP
rs1449419130 1901 dbSNP
rs1385833740 1910 dbSNP
rs1210127438 1917 dbSNP
rs896891492 1920 dbSNP
rs552280978 1928 dbSNP
rs564117387 1929 dbSNP
rs1341492773 1936 dbSNP
rs761616313 1938 dbSNP
rs1156676253 1941 dbSNP
rs767398617 1947 dbSNP
rs1332965507 1952 dbSNP
rs528084733 1954 dbSNP
rs1446327960 1955 dbSNP
rs972777333 1959 dbSNP
rs1428816135 1966 dbSNP
rs952485064 1966 dbSNP
rs201318888 1971 dbSNP
rs34926460 1971 dbSNP
rs397695673 1971 dbSNP
rs200883380 1976 dbSNP
rs1419930314 1980 dbSNP
rs1171996239 1984 dbSNP
rs1247965166 1984 dbSNP
rs1476994623 1984 dbSNP
rs199853475 1995 dbSNP
rs1025322971 1996 dbSNP
rs1018176237 2002 dbSNP
rs1457068873 2007 dbSNP
rs964724360 2015 dbSNP
rs1200101630 2031 dbSNP
rs952942252 2033 dbSNP
rs1278342746 2043 dbSNP
rs1217990525 2048 dbSNP
rs373631313 2058 dbSNP
rs1275547950 2059 dbSNP
rs984361918 2064 dbSNP
rs1374735970 2066 dbSNP
rs911381835 2085 dbSNP
rs942911721 2092 dbSNP
rs200326171 2101 dbSNP
rs34341453 2101 dbSNP
rs386650881 2102 dbSNP
rs1469995 2103 dbSNP
rs35606151 2103 dbSNP
rs1469996 2104 dbSNP
rs1427134305 2108 dbSNP
rs1238588885 2111 dbSNP
rs1377939079 2116 dbSNP
rs966811677 2116 dbSNP
rs182880860 2117 dbSNP
rs1161863358 2123 dbSNP
rs1480721031 2126 dbSNP
rs187433591 2133 dbSNP
rs1208409553 2137 dbSNP
rs1444657679 2141 dbSNP
rs113895513 2158 dbSNP
rs1276703766 2160 dbSNP
rs1351686716 2167 dbSNP
rs1311541547 2169 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' agugguaacgAUU-U-CACGUUAa 5'
                    ||| | ||||||| 
Target 5' --------uaUAAUAUGUGCAAUa 3'
 		1 - 16
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 23190.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' agUGGUAACGAU-UUCACGUUAa 5'
            || | | : | | ||||||| 
Target 5' ugACAAGUAUAAUAUGUGCAAUa 3'
 		1 - 23
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions LCL35
Disease MIMAT0000719
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1020022. RNA binding protein: AGO2. Condition:EBV B95-8-infected ...

- Skalsky RL; Corcoran DL; Gottwein E; Frank et al., 2012, PLoS pathogens.

Article - Skalsky RL; Corcoran DL; Gottwein E; Frank et al.
- PLoS pathogens, 2012
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role in viral oncogenesis. To date, only a limited number of EBV miRNA targets have been identified; thus, the role of EBV miRNAs in viral pathogenesis and/or lymphomagenesis is not well defined. Here, we used photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) combined with deep sequencing and computational analysis to comprehensively examine the viral and cellular miRNA targetome in EBV strain B95-8-infected lymphoblastoid cell lines (LCLs). We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs. 24 PAR-CLIP-identified miRNA:3'UTR interactions were confirmed by reporter assays. Our results reveal that EBV miRNAs predominantly target cellular transcripts during latent infection, thereby manipulating the host environment. Furthermore, targets of EBV miRNAs are involved in multiple cellular processes that are directly relevant to viral infection, including innate immunity, cell survival, and cell proliferation. Finally, we present evidence that myc-regulated host miRNAs from the miR-17/92 cluster can regulate latent viral gene expression. This comprehensive survey of the miRNA targetome in EBV-infected B cells represents a key step towards defining the functions of EBV-encoded miRNAs, and potentially, identifying novel therapeutic targets for EBV-associated malignancies.
LinkOut: [PMID: 22291592]
Experimental Support 4 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 23190.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065667. RNA binding protein: AGO1. Condition:4-thiouridine "PAR-CLIP data was present in GSM1065670. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000272638.9 | 3UTR | UAUAAUAUGUGCAAUAAUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000272638.9 | 3UTR | UGACAAGUAUAAUAUGUGCAAUAAUCAUUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1065667
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_6
Location of target site ENST00000272638.9 | 3UTR | UGACAAGUAUAAUAUGUGCAAUAAUCAUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM1065670
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / 4-thiouridine, 3_ML_LG
Location of target site ENST00000272638.9 | 3UTR | UGACAAGUAUAAUAUGUGCAAUAAUCAUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM1020022
Method / RBP PAR-CLIP / AGO2
Cell line / Condition LCL35 / EBV B95-8-infected, 4-thiouridine, RNase T1
Location of target site ENST00000272638.9 | 3UTR | ACAAGUAUAAUAUGUGCAAUAAUCAUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22291592 / GSE41437
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28260 Renal cortex and medulla -0.773 9.7e-4 -0.658 7.2e-3 13 Click to see details
GSE42095 Differentiated embryonic stem cells -0.484 9.6e-3 -0.434 1.9e-2 23 Click to see details
GSE28544 Breast cancer -0.414 2.2e-2 -0.318 6.5e-2 24 Click to see details
GSE21849 B cell lymphoma -0.37 2.4e-2 -0.463 5.7e-3 29 Click to see details
GSE17498 Multiple myeloma 0.255 5.6e-2 0.395 5.8e-3 40 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.243 1.2e-1 0.328 5.5e-2 25 Click to see details
GSE17306 Multiple myeloma -0.156 1.4e-1 0.318 1.3e-2 49 Click to see details
GSE38226 Liver fibrosis -0.218 1.7e-1 -0.271 1.2e-1 21 Click to see details
GSE19350 CNS germ cell tumors 0.224 2.4e-1 0.147 3.2e-1 12 Click to see details
GSE32688 Pancreatic cancer 0.12 2.6e-1 -0.093 3.1e-1 32 Click to see details
GSE21687 Ependynoma primary tumors -0.052 3.4e-1 -0.143 1.3e-1 64 Click to see details
GSE14794 Lymphoblastoid cells -0.036 3.7e-1 -0.099 1.8e-1 90 Click to see details
GSE27834 Pluripotent stem cells 0.066 4.0e-1 0.024 4.6e-1 16 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.033 4.5e-1 -0.337 7.3e-2 20 Click to see details
GSE26953 Aortic valvular endothelial cells 0.015 4.7e-1 -0.123 2.8e-1 24 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.01 4.9e-1 -0.200 3.7e-1 5 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.01 4.9e-1 -0.200 3.7e-1 5 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
255 hsa-miR-367-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055315 DUSP5 dual specificity phosphatase 5 2 8
MIRT055791 PLEKHA1 pleckstrin homology domain containing A1 2 12
MIRT057114 DDIT4 DNA damage inducible transcript 4 2 4
MIRT059663 GATAD2B GATA zinc finger domain containing 2B 2 2
MIRT059926 ZDHHC5 zinc finger DHHC-type containing 5 2 2
MIRT061610 BTG2 BTG anti-proliferation factor 2 2 6
MIRT066478 HMGA2 high mobility group AT-hook 2 2 2
MIRT069388 ZFYVE21 zinc finger FYVE-type containing 21 2 2
MIRT069972 GEMIN2 gem nuclear organelle associated protein 2 2 2
MIRT074764 CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 2 2
MIRT076199 GID4 GID complex subunit 4 homolog 2 6
MIRT077512 UBE2Z ubiquitin conjugating enzyme E2 Z 2 4
MIRT077903 TOB1 transducer of ERBB2, 1 2 6
MIRT082250 MED29 mediator complex subunit 29 2 4
MIRT082434 CIC capicua transcriptional repressor 2 6
MIRT082474 PPP1R37 protein phosphatase 1 regulatory subunit 37 2 2
MIRT082778 ZNF264 zinc finger protein 264 2 2
MIRT084533 BCL2L11 BCL2 like 11 2 8
MIRT085309 UBXN4 UBX domain protein 4 2 8
MIRT086365 SSFA2 sperm specific antigen 2 2 8
MIRT087455 NF2 neurofibromin 2 2 2
MIRT088865 FOXN2 forkhead box N2 2 12
MIRT092185 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 2 6
MIRT092326 EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 2 6
MIRT093533 GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 2 6
MIRT096935 PAPD7 poly(A) RNA polymerase D7, non-canonical 2 8
MIRT097026 MAP1B microtubule associated protein 1B 2 4
MIRT099137 MYLIP myosin regulatory light chain interacting protein 2 6
MIRT099905 SOX4 SRY-box 4 2 12
MIRT102289 DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 2 10
MIRT102507 KLHDC10 kelch domain containing 10 2 2
MIRT102891 INSIG1 insulin induced gene 1 2 2
MIRT109188 VMA21 VMA21, vacuolar ATPase assembly factor 2 4
MIRT124567 PRRC2B proline rich coiled-coil 2B 2 2
MIRT135568 SPRYD4 SPRY domain containing 4 2 2
MIRT161135 SLC25A36 solute carrier family 25 member 36 2 6
MIRT163995 KIAA1109 KIAA1109 2 4
MIRT164689 RNF4 ring finger protein 4 2 2
MIRT167705 HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 2 8
MIRT178956 USP28 ubiquitin specific peptidase 28 2 2
MIRT185717 ARNTL2 aryl hydrocarbon receptor nuclear translocator like 2 2 2
MIRT186264 TCEB3 elongin A 2 2
MIRT186537 TWF1 twinfilin actin binding protein 1 2 4
MIRT186628 COX20 COX20, cytochrome c oxidase assembly factor 2 8
MIRT189373 TXLNA taxilin alpha 2 4
MIRT197013 EIF1 eukaryotic translation initiation factor 1 2 10
MIRT206437 YIPF4 Yip1 domain family member 4 2 2
MIRT211228 FGF2 fibroblast growth factor 2 2 10
MIRT214529 C5ORF24 chromosome 5 open reading frame 24 2 2
MIRT216034 IL6ST interleukin 6 signal transducer 2 10
MIRT218084 TULP4 tubby like protein 4 2 2
MIRT242418 CCDC113 coiled-coil domain containing 113 2 2
MIRT243162 SOX11 SRY-box 11 2 2
MIRT250943 CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 2 4
MIRT253350 ZNF417 zinc finger protein 417 2 2
MIRT271968 ARF1 ADP ribosylation factor 1 2 2
MIRT273214 ZNF695 zinc finger protein 695 2 4
MIRT296114 SLC12A5 solute carrier family 12 member 5 2 2
MIRT301711 TEF TEF, PAR bZIP transcription factor 2 2
MIRT316477 ARID1B AT-rich interaction domain 1B 2 6
MIRT322174 CLN8 CLN8, transmembrane ER and ERGIC protein 2 4
MIRT341538 CNIH1 cornichon family AMPA receptor auxiliary protein 1 2 6
MIRT356062 SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 2 2
MIRT443579 PPIC peptidylprolyl isomerase C 2 2
MIRT448825 FKBP1A FK506 binding protein 1A 2 4
MIRT451494 FOPNL FGFR1OP N-terminal like 2 2
MIRT452694 MDM2 MDM2 proto-oncogene 2 2
MIRT453167 CNOT4 CCR4-NOT transcription complex subunit 4 2 6
MIRT454588 SLC33A1 solute carrier family 33 member 1 2 4
MIRT455794 TAF8 TATA-box binding protein associated factor 8 2 4
MIRT456010 CYP2C19 cytochrome P450 family 2 subfamily C member 19 2 2
MIRT456044 KIAA1586 KIAA1586 2 2
MIRT456763 TMEM239 transmembrane protein 239 2 4
MIRT458068 NLRP9 NLR family pyrin domain containing 9 2 2
MIRT459230 MRPS21 mitochondrial ribosomal protein S21 2 2
MIRT459534 MFF mitochondrial fission factor 2 6
MIRT459759 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT460236 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT461104 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT462924 ZNRF3 zinc and ring finger 3 2 2
MIRT463476 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT463516 ZBTB8B zinc finger and BTB domain containing 8B 2 4
MIRT465503 TOR1B torsin family 1 member B 2 2
MIRT469525 RBFOX2 RNA binding protein, fox-1 homolog 2 2 8
MIRT470079 PTGES2 prostaglandin E synthase 2 2 2
MIRT471581 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT473451 MCOLN2 mucolipin 2 2 8
MIRT475882 H3F3C H3 histone family member 3C 2 10
MIRT475915 H3F3B H3 histone family member 3B 2 8
MIRT476195 GOLGA8A golgin A8 family member A 2 10
MIRT476318 GM2A GM2 ganglioside activator 2 2
MIRT476676 FUT11 fucosyltransferase 11 2 10
MIRT478368 DDI2 DNA damage inducible 1 homolog 2 2 2
MIRT479545 CDC5L cell division cycle 5 like 2 2
MIRT481024 BAZ2B bromodomain adjacent to zinc finger domain 2B 2 2
MIRT491009 ATF7IP activating transcription factor 7 interacting protein 2 2
MIRT493168 MKNK2 MAP kinase interacting serine/threonine kinase 2 2 2
MIRT494345 CASKIN1 CASK interacting protein 1 2 2
MIRT499087 ZDHHC21 zinc finger DHHC-type containing 21 2 6
MIRT500029 ABCF2 ATP binding cassette subfamily F member 2 2 8
MIRT501298 RRN3 RRN3 homolog, RNA polymerase I transcription factor 2 4
MIRT503124 BCL11B B-cell CLL/lymphoma 11B 2 8
MIRT503301 GTF2A1 general transcription factor IIA subunit 1 2 6
MIRT504328 ASGR2 asialoglycoprotein receptor 2 2 6
MIRT504471 EID2B EP300 interacting inhibitor of differentiation 2B 2 2
MIRT504655 RPL9 ribosomal protein L9 2 6
MIRT505331 TMF1 TATA element modulatory factor 1 2 8
MIRT505732 SERTAD3 SERTA domain containing 3 2 4
MIRT505827 RSBN1 round spermatid basic protein 1 2 8
MIRT506004 PURG purine rich element binding protein G 2 8
MIRT506308 PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 2 6
MIRT506806 KLHL15 kelch like family member 15 2 6
MIRT507119 GOLGA8B golgin A8 family member B 2 6
MIRT507353 FAM129A family with sequence similarity 129 member A 2 6
MIRT507591 DDX3X DEAD-box helicase 3, X-linked 2 4
MIRT507674 CPEB4 cytoplasmic polyadenylation element binding protein 4 2 4
MIRT507703 CNOT2 CCR4-NOT transcription complex subunit 2 2 8
MIRT508012 BCAT1 branched chain amino acid transaminase 1 2 4
MIRT510439 ZIC5 Zic family member 5 2 6
MIRT510539 XKR7 XK related 7 2 4
MIRT510600 TPPP tubulin polymerization promoting protein 2 6
MIRT511060 NRAS NRAS proto-oncogene, GTPase 2 4
MIRT511855 GOLGA8J golgin A8 family member J 2 6
MIRT511865 GOLGA8I golgin A8 family member I, pseudogene 1 3
MIRT512570 CTDSPL CTD small phosphatase like 2 2
MIRT512708 ZNF134 zinc finger protein 134 2 6
MIRT513177 MOAP1 modulator of apoptosis 1 2 6
MIRT513783 PAWR pro-apoptotic WT1 regulator 2 6
MIRT515099 IRGQ immunity related GTPase Q 2 2
MIRT515481 INCENP inner centromere protein 2 4
MIRT517416 BMP8A bone morphogenetic protein 8a 2 2
MIRT518754 C1orf35 chromosome 1 open reading frame 35 2 2
MIRT519780 ZNF354B zinc finger protein 354B 2 4
MIRT519865 ZFP62 ZFP62 zinc finger protein 2 6
MIRT520510 TRAM2 translocation associated membrane protein 2 2 6
MIRT521068 SLC25A32 solute carrier family 25 member 32 2 6
MIRT526912 ZNF772 zinc finger protein 772 2 6
MIRT527134 GULP1 GULP, engulfment adaptor PTB domain containing 1 2 2
MIRT527867 SLC39A14 solute carrier family 39 member 14 2 2
MIRT528404 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 2 2
MIRT532956 ZNF24 zinc finger protein 24 2 4
MIRT533021 ZFC3H1 zinc finger C3H1-type containing 2 4
MIRT533191 WASL Wiskott-Aldrich syndrome like 2 6
MIRT534191 SLC7A11 solute carrier family 7 member 11 2 2
MIRT534961 PTAR1 protein prenyltransferase alpha subunit repeat containing 1 2 4
MIRT536396 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT537046 GRAMD4 GRAM domain containing 4 2 2
MIRT537125 GOLGA3 golgin A3 2 4
MIRT537183 GFPT2 glutamine-fructose-6-phosphate transaminase 2 2 4
MIRT537652 ERGIC2 ERGIC and golgi 2 2 4
MIRT538632 CCSER2 coiled-coil serine rich protein 2 2 4
MIRT539231 ANP32E acidic nuclear phosphoprotein 32 family member E 2 6
MIRT540099 NPY4R neuropeptide Y receptor Y4 2 2
MIRT540998 ZNF460 zinc finger protein 460 2 4
MIRT541468 AURKA aurora kinase A 2 2
MIRT542680 SESN3 sestrin 3 2 2
MIRT542757 PRRG4 proline rich and Gla domain 4 2 2
MIRT542863 NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 2 2
MIRT542925 HOXC8 homeobox C8 2 2
MIRT543747 SZRD1 SUZ RNA binding domain containing 1 2 2
MIRT544404 ZSCAN12 zinc finger and SCAN domain containing 12 2 2
MIRT544583 AP5Z1 adaptor related protein complex 5 zeta 1 subunit 2 4
MIRT544662 MED19 mediator complex subunit 19 2 2
MIRT545251 GTF2E1 general transcription factor IIE subunit 1 2 2
MIRT545261 TRIM36 tripartite motif containing 36 2 4
MIRT545744 UHRF1BP1 UHRF1 binding protein 1 2 2
MIRT545999 WDR81 WD repeat domain 81 2 2
MIRT546038 VPS4B vacuolar protein sorting 4 homolog B 2 2
MIRT547170 PDZD8 PDZ domain containing 8 2 2
MIRT547273 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT547729 KIF5B kinesin family member 5B 2 2
MIRT548127 GATA6 GATA binding protein 6 2 2
MIRT548203 FNIP1 folliculin interacting protein 1 2 2
MIRT548756 CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2 2
MIRT549641 ZNF75A zinc finger protein 75a 2 2
MIRT549684 ZNF598 zinc finger protein 598 2 2
MIRT550197 MRO maestro 2 2
MIRT550340 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT550536 MYZAP myocardial zonula adherens protein 2 2
MIRT550975 TOR4A torsin family 4 member A 2 2
MIRT551221 CIDEC cell death inducing DFFA like effector c 2 2
MIRT551355 AGBL5 ATP/GTP binding protein like 5 2 2
MIRT551571 LETM1 leucine zipper and EF-hand containing transmembrane protein 1 2 2
MIRT552277 RAB3D RAB3D, member RAS oncogene family 2 2
MIRT552661 ZADH2 zinc binding alcohol dehydrogenase domain containing 2 2 2
MIRT553081 UCK2 uridine-cytidine kinase 2 2 2
MIRT553753 TBC1D8 TBC1 domain family member 8 2 2
MIRT554030 SPCS3 signal peptidase complex subunit 3 2 2
MIRT554099 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT554155 SLX4 SLX4 structure-specific endonuclease subunit 2 2
MIRT554815 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT555522 PMEPA1 prostate transmembrane protein, androgen induced 1 2 2
MIRT555597 PIP5K1C phosphatidylinositol-4-phosphate 5-kinase type 1 gamma 2 2
MIRT555632 PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2 4
MIRT555679 PGAM4 phosphoglycerate mutase family member 4 2 4
MIRT555827 PAX9 paired box 9 2 2
MIRT555868 PAIP1 poly(A) binding protein interacting protein 1 2 2
MIRT555939 NUP43 nucleoporin 43 2 2
MIRT555994 NFYB nuclear transcription factor Y subunit beta 2 2
MIRT556340 MAP2K4 mitogen-activated protein kinase kinase 4 2 2
MIRT556432 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT556585 LHFPL2 LHFPL tetraspan subfamily member 2 2 4
MIRT556801 KIAA1958 KIAA1958 2 2
MIRT558047 EXOC5 exocyst complex component 5 2 2
MIRT558697 CLTA clathrin light chain A 2 2
MIRT559191 BMPR1A bone morphogenetic protein receptor type 1A 2 4
MIRT559639 AKAP10 A-kinase anchoring protein 10 2 2
MIRT559707 AEN apoptosis enhancing nuclease 2 2
MIRT560673 SRFBP1 serum response factor binding protein 1 2 2
MIRT560990 GPBP1L1 GC-rich promoter binding protein 1 like 1 2 2
MIRT562170 HOXA13 homeobox A13 2 2
MIRT562275 GNAQ G protein subunit alpha q 2 2
MIRT563624 ZNF277 zinc finger protein 277 2 2
MIRT563815 FMN1 formin 1 2 2
MIRT564096 TLR3 toll like receptor 3 2 2
MIRT565320 TMEM41A transmembrane protein 41A 2 2
MIRT565986 RNF44 ring finger protein 44 2 2
MIRT566047 REV3L REV3 like, DNA directed polymerase zeta catalytic subunit 2 2
MIRT568236 C11orf24 chromosome 11 open reading frame 24 2 2
MIRT568310 BAK1 BCL2 antagonist/killer 1 2 2
MIRT572376 ATOX1 antioxidant 1 copper chaperone 2 2
MIRT574822 CPEB3 cytoplasmic polyadenylation element binding protein 3 2 2
MIRT609212 PELP1 proline, glutamate and leucine rich protein 1 2 2
MIRT616217 RBM27 RNA binding motif protein 27 2 2
MIRT629087 FASLG Fas ligand 2 2
MIRT632124 FKBP9 FK506 binding protein 9 2 2
MIRT632576 POLQ DNA polymerase theta 2 2
MIRT634799 ENTHD1 ENTH domain containing 1 2 2
MIRT636553 ESRP1 epithelial splicing regulatory protein 1 2 2
MIRT640977 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT653875 SH2B3 SH2B adaptor protein 3 2 2
MIRT655598 OTUD7B OTU deubiquitinase 7B 2 2
MIRT659764 CCDC171 coiled-coil domain containing 171 2 2
MIRT660744 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT681037 AAED1 AhpC/TSA antioxidant enzyme domain containing 1 2 2
MIRT682305 RBM28 RNA binding motif protein 28 2 2
MIRT682573 EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2 2
MIRT686217 ZNF267 zinc finger protein 267 2 2
MIRT687209 PLXNA3 plexin A3 2 2
MIRT690630 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT692419 AGMAT agmatinase 2 2
MIRT694437 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 2
MIRT700725 PNO1 partner of NOB1 homolog 2 2
MIRT701549 NARF nuclear prelamin A recognition factor 2 2
MIRT704379 DAND5 DAN domain BMP antagonist family member 5 2 2
MIRT707935 PPP1R3D protein phosphatase 1 regulatory subunit 3D 2 2
MIRT709939 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT711371 MED7 mediator complex subunit 7 2 2
MIRT712327 PER2 period circadian clock 2 2 2
MIRT714515 SHE Src homology 2 domain containing E 2 2
MIRT715520 G2E3 G2/M-phase specific E3 ubiquitin protein ligase 2 2
MIRT724294 OSMR oncostatin M receptor 2 2
MIRT725358 MUC21 mucin 21, cell surface associated 2 2
MIRT732242 KLF4 Kruppel like factor 4 3 1
MIRT735384 SPAG5 sperm associated antigen 5 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-367 Medpor NULL NULL Microarray osteoblast-like cells line (MG-63) 18408260 2008 up-regulated
miR-367 Activin A NULL 229455 Quantitative real-time PCR Human embryonic stem (hES) cells 19885849 2010 up-regulated
miR-367 Mistletoe lectin-I NULL NULL Microarray colorectal cancer cells CLY cells 20955366 2011 down-regulated
miR-367 Doxorubicin approved 31703 Quantitative real-time PCR heart 22859947 2012 up-regulated
miR-367 Paclitaxel approved 36314 Microarray Ovarian cancer cell lines 24220856 2014 up-regulated
miR-367 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-367 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-miR-367-3p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Siop Treatment Protocol sensitive High Nephroblastoma tissue
hsa-miR-367-3p Paclitaxel 36314 NSC125973 approved resistant High Pan-Cancer cell line (NCI-H460, NCI-H522, NCI-H322M, HOP62, A549, EKVX, MALME-3M, NCI-H226, HT-29, HCT-116, SE-620, HCT-15, HCC2998, COLO205, HS-578T, NCI/ADR-RES, OVCAR8, OVCAR4, ACHN, SN-12C, 786-O, CAKI-1, UO-31, TK-10, A498, SK-MEL-28, UACC-257, M14, UACC-62, SK
hsa-miR-367-3p Doxorubicin 31703 NSC123127 approved sensitive High Hepatocellular Carcinoma tissue and cell line (HepG2)
hsa-miR-367-3p Mitoxantrone 4212 NSC279836 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Sorafenib 216239 NSC747971 approved sensitive Low Hepatocellular Carcinoma cell line (SKhep1, HA22T)
hsa-miR-367-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-367-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM16)
hsa-miR-367-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM36)
hsa-miR-367-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-miR-367-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (SKOV3)
hsa-miR-367-3p Cisplatin 5460033 NSC119875 approved resistant cell line (IGROV-1)
hsa-miR-367-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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