miRTarBase - #MIRT093589


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pre-miRNA Information
pre-miRNA hsa-mir-106a   
Genomic Coordinates chrX: 134170198 - 134170278
Description Homo sapiens miR-106a stem-loop
Comment This miRNA was not cloned in reference .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-106a-3p
Sequence 50| CUGCAAUGUAAGCACUUCUUAC |71
Evidence Experimental
Experiments Cloned
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs927823355 6 dbSNP
rs1448271699 8 dbSNP
rs1477844174 12 dbSNP
rs1358970494 18 dbSNP
rs781747706 21 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Biomarker Information
Biomarker ID Name Type Discovered From Mode Level Source Testing Methods
BN3X2A miR-106a Predictive Biomarker (PRD) Clinical/Experimental Data Expression Decrease Tumor tissue Quantitative real-time PCR
Gene Information
Gene Symbol SPCS3   
Synonyms PRO3567, SPC22/23, SPC3, YLR066W
Description signal peptidase complex subunit 3
Transcript NM_021928   
Expression
Putative miRNA Targets on SPCS3
3'UTR of SPCS3
(miRNA target sites are highlighted)		 
>SPCS3|NM_021928|3'UTR
   1 ATTATTCTGAATTTGAAACAACATATTTTTATACTTAATGAATTGTATCTCATTAATCTCTTCCCTTACATCTTCATGTA
  81 TTGTTGGTTTGTTTTTTGGTTTTGGGTTTTTTTTTTTTTTTTTTTGGTATAAGAACTAACATCAAAAGGCCTGTTTAAAG
 161 GGAAAGGTTAATGGGCTACTTAATATTATGAACAAAACAAAAAAACAAGGCTGCCACAGTGGAATATTATCTTACAAGAA
 241 TAAGAACTACATAAAACAGATTTGTAAAAAATACATATTTGAAGTATTCCCTGTATTTCCATTATTCTTTATGGAATATA
 321 AAGTAAGCATGAAAGGTAGTTAAAACTTTCAGGTGCCTGTAGAGTCATAATAACTGTATTTTATGCCTTGCATTCACGCA
 401 AATTCACATTGGATGTGATTTAAAAGTAGACATTCTCTTTTTCCTCTTTTAGGATATGTTTGATTACTGGAAAATTAATA
 481 TGGTTATTTGTTAGAAGTCTGGTTTATAAAAAAGCCAAAAGTGATGGAATTTATTCCATTTGTCTTAGGAAGGCCCATAA
 561 TACTTGTTTTTCTTACATGTGACTAGCAACTTTCTCCACTTAAAGACTAAATACCTCTTTATATGATGTAAATTATTCTA
 641 ATTCATTTTAAAATCTTTTAGGTCAGCAAAATGTGTGTCTTCAGTGCTTTCTCTAAAAACGTTCCTTTATAGCTTTGTAC
 721 TTTTTTTTTTAGCGTTGCCATTGAAAGTTAAAATGTTTGCATGGTTTACCCTCTGAGTTATGTTTCTTCTAGTGAGCATG
 801 CCTGCTGTCACTAAGTGAATTATTTACTACTTTTTGTAGGTCTATATTTTAATAATTATTGGGATAATAATAATTGTGGT
 881 ATGCTTTCCATTTACAAACCACTCATATACTTTAGTGTATGTCATCCTCAATAATCTAATGAGGTAAGTAGTATAAGTGT
 961 TAGCTCTTTGCAGATAAGAAACTGAAACCCAGAAGTTTATTGAATTGCTTCATTGTTACCTAGCCAGCAAGGAGTGGAAT
1041 TAAAACTTGAACTCAGATCTTCTAATTTTCTGAGCTCATCCTTTCTCTTATACCTCAGATTGCAGACTAATCAAATTTTA
1121 CTTAAAACCTTCCTGATATTTTTGTTACCCTGGACACCCTTTCTATTCTAGAAAAGGTTTCCCATTTTATATGGAAGTGA
1201 CTAATTTTCAAGCTGCCAACAACTTATATCGAGGTAATATTTTATTCTCTGAATAAATTCATTTCACTTATATTAAAAGC
1281 ATAAGGAAATCTACATGTATGTAAAAATAACTTAGAAATTCAGTACATAATACATGATTGAATACATGATCGTATTTAAC
1361 ATGTTTTTTTTTTCTGCAGTGGACAAATAAACATCCTCAAAGTAGCAACTGCAAATCAGTTACCCTTAGAAAAGCAAGAC
1441 CAAACACTGTAGTTACACTATTAGCAGTGACCAAAAAGGGCTAATATTTTCTAAGAATAGTTTAAATTACAGACATTTGT
1521 TATATTTACCTTATGTGAAATACATCACTATTTAATTACATTAATTTTAACATCTGTTGTGTGGAGTTGTATAGTTCATG
1601 CAAAAGCCTGTGGGTATGGGTTTTTCAAACCAGCAGAAAGGTCAAAGGTACCTGAATGCTAAACTGCCTGGCTCCCAGCT
1681 TTTTCATTAAACTTTTCAGGGTCTTGGTTTCTTTATCTGTAAAATGACAGAGTTGGACCAGTTAACTTTAATGGCCATCC
1761 TTTTACACCACACAAGTTGATAAAATTTATCTGTTCAGCAAAGAGATTGAACAAAAAAGCACGTTAGTAATATGAAGACA
1841 GGAAAACGAATGAAAGTCTAACACATAACTCATATTGATTTACTTTATTTCTGTTAGATTTTACACTCTGAAAATTTCAC
1921 CTCATTTAGTTTGTACAAATACTAGACATGGAAACTTAAAATGTGCAGGTGTCAAAGCTTAAAAATCAGGTGTGTCCTCT
2001 TTAAAGGCATGTGCGATAAGCCTGCAGTCTTAACCAGACCTGGTACCAGTTTAACAGTTCATGATACTTCTGTGATGAGT
2081 GGATCTGTTAGTCTGGTAGAGATTAATGTTGAAATTTACTTGAATTACAGTTATTTGACAAGCCCACTTTTTTTGGAGTT
2161 TGGTGAGGAAGATAAGTAAAAATGCCCAACTAGTACAATGTGGAGAAAGTTTTCTGTTTGCTTGACTAAGGGAAATTGCT
2241 CAGAAAAAGAATGCTCCAACATGGGAATAAGGACCTTCAGTCTCAGGAACTCATTTTTGGGTGCAGTTTCTACATTTAAA
2321 AAATTGACTTGTGTTCAGTTTGATAACCAGTTCATTTGCTTTAGTCTCAGTGTTTTAAAGAAGTCTCATAATGTTCTACA
2401 AAGACACAAAGCTTCAGGCTTATACAAAACTGAGTATGATTAGAAATACCTGAGCCCAGAAATGATTCTGAGAAAAGAGA
2481 ATAATTTGAAGACACTTATTTAAAAGTAATTATGGTTAGAAATGAATTAATTTAAAAATGTGTTCACATATCCCTTTCTC
2561 TAACAGTTTAACCTAGACAAACATCTGTATCAGTATTTTTTTATTCCCCTGATTGATTACATTTGGTTTCTTTATTCTGA
2641 AAGGAAAATAACAAAAACTTCAGAAATTCCTAAGGGTGTAATAAGAAAGTGGGTTTTGAGTTTCCTTTCCTGGAATTATT
2721 TTACAGTTCTTTGGTGGGTCTCGTCAGCCAATTCATAGCTGGGCTTTAAGATTATCATCTTAGAGATGATAGATGGGCTT
2801 TTTAAAGATTTCATCTTAGAGATGAAAAGCTGGGCTTTTTCTCTAAGATGATAATCTTAAAGCCCAGCTATTAATTGATA
2881 ATGAACATTTTTCACTATTTTTTTTTCTATCTGAAGCTTAGAGATCTAGAGCTTTGGATCTTTCGGGTATATGTCAATGG
2961 AGGTATTATTTTATAATACTTTGCATTGACATGAAGTGGGTTCATGGGGGAAAACCATGAGCTGTGAACATTGGTAGCAA
3041 ACAAGCATATATTCATTTCAAAACTTTCCTTGCTTTTAGCAGAGAGAAGCCTGTATATGTTACATGTGTGACTTTCAGTA
3121 GTTTAAAGAGATGTTTCAAAAAATTGTTGCATGTTTTTGATGCAATTTGGGAAATTGTTTACTTCACAATGTAGTCATTC
3201 ATAAAAAAATTCATGAAAATACTGAACATATGTTTGAGGATTTTTCTTTTCCTTTTTAAATTTTTTTATTTTTTCTGAGA
3281 CGGAGATCTGCTCTTACGCCCAGGCTAGAGTGAAGTGGCGCGATCTTGGCTTACTGCAACCTCCACCCCCCAGGTTCAAG
3361 CGATTCTCCTGCCTCAGCCTCCGGAGTAGCTGGGATTACAGGCGCCCGCCACCACGTCCGGCTAATTTTTGTATTTTCAG
3441 TAGAGACGGGGTTTTGCTATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCTGCCTCGGCCTCCCAA
3521 AGTGTTAGGATAACAGGTGTGAGCCACCGTGCCCGGCTGAAGATTTTTCTTAATTGCAATAAATATTCAGCATTTTTTCT
3601 AATGAAAATGAATTTTGTTTACCAGTAAAAGTATGCATTTTAAAAGACTTTCAGATTTATGCTTTTTACGTGAAGCTGCT
3681 AAACTAAAAGTAAATGGAAGAAACCAAGTCTAGTAGGTTTTTTCTTTTTTTTTGTGGGGGTGGGATGGGGGAGGTTAGTT
3761 ACACTTAAAATATCTTCTCCAGAGACTGTATGCTCCTATACTAGACTGTAAGCTCTTTGAGGGCAGTCTGTCAGATTTAT
3841 CTTTGTATCTTCCCCAGCGCCTAGTGTAGTGCCTTGCACATAATAGGCGCCCAATAAATATTGATGAAGAATGAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cauuCUUCACGAAUGUAACGuc 5'
              ||| ||||| |||||:  
Target 5' tattGAATTGCTT-CATTGTta 3'
 998 - 1018 133.00 -10.70
2 
miRNA  3' cauUCUUCACGAAU---GUAACGUc 5'
             | ||||| |||   | ||||| 
Target 5' agtATAAGTG-TTAGCTCTTTGCAg 3'
 950 - 973 130.00 -14.90
3 
miRNA  3' caUUCUUCACGAA------U-GUAACGUc 5'
            ||||: ||:||      | ::||||| 
Target 5' taAAGAGATGTTTCAAAAAATTGTTGCAt 3'
 3124 - 3152 126.00 -7.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30633175 15 COSMIC
COSN31594014 20 COSMIC
COSN18729326 53 COSMIC
COSN23489451 59 COSMIC
COSN14616954 92 COSMIC
COSN27220148 120 COSMIC
COSN27586088 126 COSMIC
COSN17182035 192 COSMIC
COSN15003322 412 COSMIC
COSN31962357 519 COSMIC
COSN29008962 731 COSMIC
COSN15995819 761 COSMIC
COSN27164029 932 COSMIC
COSN27443958 1374 COSMIC
COSN20091133 1399 COSMIC
COSN5562480 1411 COSMIC
COSN6815981 1592 COSMIC
COSN2010063 1741 COSMIC
COSN22829323 1860 COSMIC
COSN26715572 1860 COSMIC
COSN32064772 1875 COSMIC
COSN25244561 1920 COSMIC
COSN20091134 2054 COSMIC
COSN26194027 2725 COSMIC
COSN32061951 2770 COSMIC
COSN22813678 2907 COSMIC
COSN1292216 3003 COSMIC
COSN31778384 3022 COSMIC
COSN9891208 3124 COSMIC
COSN6815982 3226 COSMIC
COSN25828535 3357 COSMIC
COSN20100823 3734 COSMIC
COSN7754429 3753 COSMIC
COSN14891508 3755 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs778185241 2 dbSNP
rs768201113 12 dbSNP
rs749779008 15 dbSNP
rs1276986486 22 dbSNP
rs1380295499 23 dbSNP
rs1359634092 24 dbSNP
rs1204039385 28 dbSNP
rs376892490 32 dbSNP
rs773871178 35 dbSNP
rs1194489276 36 dbSNP
rs1434843781 38 dbSNP
rs745519581 42 dbSNP
rs1443159957 46 dbSNP
rs369185461 48 dbSNP
rs1386111093 49 dbSNP
rs956828587 52 dbSNP
rs2278903 53 dbSNP
rs914885674 56 dbSNP
rs796571936 57 dbSNP
rs1262335244 61 dbSNP
rs942400778 71 dbSNP
rs112954848 76 dbSNP
rs1189398187 79 dbSNP
rs994679249 92 dbSNP
rs933296307 94 dbSNP
rs922333942 98 dbSNP
rs1217891849 99 dbSNP
rs199777393 100 dbSNP
rs907896196 104 dbSNP
rs13102347 105 dbSNP
rs1304125963 107 dbSNP
rs1310399081 107 dbSNP
rs1330762143 107 dbSNP
rs1449306457 107 dbSNP
rs1491095157 107 dbSNP
rs199867915 107 dbSNP
rs55821823 107 dbSNP
rs569173317 107 dbSNP
rs764818670 107 dbSNP
rs879092516 107 dbSNP
rs1491513198 108 dbSNP
rs71596635 108 dbSNP
rs1180159936 109 dbSNP
rs1360956096 109 dbSNP
rs1173930573 110 dbSNP
rs1413810338 111 dbSNP
rs1407327100 112 dbSNP
rs774896779 112 dbSNP
rs1419962928 113 dbSNP
rs1491067013 113 dbSNP
rs1037992023 114 dbSNP
rs1180224349 114 dbSNP
rs899298516 116 dbSNP
rs1357576101 125 dbSNP
rs1434506344 126 dbSNP
rs1483975427 126 dbSNP
rs75649262 127 dbSNP
rs1377839470 130 dbSNP
rs1408513488 132 dbSNP
rs886326472 134 dbSNP
rs1277323897 137 dbSNP
rs1347727805 150 dbSNP
rs1371975374 163 dbSNP
rs1012425058 165 dbSNP
rs1375139124 166 dbSNP
rs1306635152 169 dbSNP
rs141379995 172 dbSNP
rs1381487609 176 dbSNP
rs1301128616 179 dbSNP
rs1044146225 184 dbSNP
rs565642075 186 dbSNP
rs1002648493 187 dbSNP
rs1035761155 188 dbSNP
rs1379427804 189 dbSNP
rs1165088533 191 dbSNP
rs1425145121 194 dbSNP
rs1264610872 199 dbSNP
rs555951901 199 dbSNP
rs12643094 201 dbSNP
rs1352029519 204 dbSNP
rs1260475333 207 dbSNP
rs1245843778 218 dbSNP
rs1323683124 219 dbSNP
rs1209923980 222 dbSNP
rs1010533774 232 dbSNP
rs1021497165 236 dbSNP
rs1300013679 238 dbSNP
rs886612790 240 dbSNP
rs968497509 253 dbSNP
rs1486641123 258 dbSNP
rs1384012907 265 dbSNP
rs1293846923 266 dbSNP
rs974559892 266 dbSNP
rs1232445006 269 dbSNP
rs1163627711 273 dbSNP
rs1434602301 275 dbSNP
rs3733371 276 dbSNP
rs1037990660 288 dbSNP
rs34983053 289 dbSNP
rs768678458 289 dbSNP
rs1178967029 296 dbSNP
rs1261504047 301 dbSNP
rs1012276317 311 dbSNP
rs1210752056 318 dbSNP
rs1423353066 319 dbSNP
rs954941636 328 dbSNP
rs1263971287 330 dbSNP
rs1453967130 347 dbSNP
rs1023658356 352 dbSNP
rs906585396 354 dbSNP
rs1318742292 356 dbSNP
rs1003637336 360 dbSNP
rs987614550 362 dbSNP
rs150100723 364 dbSNP
rs191243241 365 dbSNP
rs1301721631 367 dbSNP
rs540473788 369 dbSNP
rs1038320532 370 dbSNP
rs1388288823 370 dbSNP
rs761352187 376 dbSNP
rs948174843 378 dbSNP
rs1045236967 379 dbSNP
rs1328771521 381 dbSNP
rs906738020 384 dbSNP
rs1200199652 398 dbSNP
rs769337489 398 dbSNP
rs1022237843 399 dbSNP
rs1435340377 402 dbSNP
rs1265667957 407 dbSNP
rs963949381 409 dbSNP
rs1260088481 410 dbSNP
rs371150435 414 dbSNP
rs1442324172 420 dbSNP
rs574590876 433 dbSNP
rs1368388601 434 dbSNP
rs891414960 436 dbSNP
rs3178600 439 dbSNP
rs1256574005 443 dbSNP
rs138377922 455 dbSNP
rs982592033 457 dbSNP
rs1302367838 473 dbSNP
rs3178599 476 dbSNP
rs1303961328 481 dbSNP
rs1349782921 482 dbSNP
rs908027502 503 dbSNP
rs574084709 519 dbSNP
rs1038340177 525 dbSNP
rs920822653 526 dbSNP
rs1021467535 527 dbSNP
rs1206755271 539 dbSNP
rs1467991254 548 dbSNP
rs1251191547 550 dbSNP
rs968594701 556 dbSNP
rs948296445 558 dbSNP
rs149280982 563 dbSNP
rs10520344 565 dbSNP
rs1240329958 577 dbSNP
rs1176984341 584 dbSNP
rs1437363882 585 dbSNP
rs1279382441 587 dbSNP
rs954604521 601 dbSNP
rs1342728923 603 dbSNP
rs1004031033 604 dbSNP
rs1167648733 612 dbSNP
rs1240524331 615 dbSNP
rs1355580168 616 dbSNP
rs1306703005 618 dbSNP
rs1440999994 628 dbSNP
rs1052562817 654 dbSNP
rs1335560426 661 dbSNP
rs1398319098 664 dbSNP
rs766488216 674 dbSNP
rs987926821 676 dbSNP
rs1173552908 677 dbSNP
rs1420750982 679 dbSNP
rs1382530959 683 dbSNP
rs144485453 685 dbSNP
rs1010717735 688 dbSNP
rs1469784756 692 dbSNP
rs1238149552 701 dbSNP
rs3733370 702 dbSNP
rs1391639528 710 dbSNP
rs1489177770 721 dbSNP
rs35238530 721 dbSNP
rs920617591 721 dbSNP
rs973416296 721 dbSNP
rs1222871181 722 dbSNP
rs1439799135 734 dbSNP
rs963896824 735 dbSNP
rs981054696 738 dbSNP
rs565216067 747 dbSNP
rs928082594 748 dbSNP
rs1401107541 756 dbSNP
rs1428411257 759 dbSNP
rs939535594 760 dbSNP
rs1340043885 774 dbSNP
rs1400358534 774 dbSNP
rs376339014 775 dbSNP
rs1165221745 778 dbSNP
rs1216240704 782 dbSNP
rs996722484 794 dbSNP
rs1194352385 802 dbSNP
rs143636450 812 dbSNP
rs1240156013 816 dbSNP
rs1214726537 817 dbSNP
rs1214332507 837 dbSNP
rs1451963173 858 dbSNP
rs1275303287 859 dbSNP
rs1207671900 880 dbSNP
rs1333567257 881 dbSNP
rs369886065 882 dbSNP
rs1445452211 887 dbSNP
rs760040446 896 dbSNP
rs1278231877 899 dbSNP
rs1219809915 900 dbSNP
rs1192966860 903 dbSNP
rs183795954 906 dbSNP
rs1268796402 914 dbSNP
rs891553987 916 dbSNP
rs1350819566 920 dbSNP
rs1325835851 922 dbSNP
rs982925993 925 dbSNP
rs908309772 928 dbSNP
rs1460045026 930 dbSNP
rs1476709176 932 dbSNP
rs1478763933 937 dbSNP
rs1417374345 941 dbSNP
rs546081182 943 dbSNP
rs1417695296 948 dbSNP
rs1478259539 949 dbSNP
rs973566195 954 dbSNP
rs1191391865 964 dbSNP
rs920768057 965 dbSNP
rs948244853 967 dbSNP
rs1199912917 970 dbSNP
rs1305257056 972 dbSNP
rs1396266250 973 dbSNP
rs1042686843 975 dbSNP
rs1045379347 976 dbSNP
rs1214474129 978 dbSNP
rs1398563447 984 dbSNP
rs1368797441 993 dbSNP
rs1276935500 998 dbSNP
rs1439014859 1008 dbSNP
rs1370439333 1010 dbSNP
rs17629999 1011 dbSNP
rs376370609 1013 dbSNP
rs996043146 1013 dbSNP
rs1169700563 1018 dbSNP
rs1414927692 1019 dbSNP
rs576847007 1020 dbSNP
rs140656410 1023 dbSNP
rs1238484413 1037 dbSNP
rs1180114023 1052 dbSNP
rs1231786159 1053 dbSNP
rs1479400291 1053 dbSNP
rs1291379384 1058 dbSNP
rs1313250332 1060 dbSNP
rs1282915067 1062 dbSNP
rs1052884984 1063 dbSNP
rs890246394 1065 dbSNP
rs892524117 1066 dbSNP
rs1347593793 1075 dbSNP
rs1011417684 1078 dbSNP
rs1043502566 1080 dbSNP
rs899716875 1081 dbSNP
rs73871984 1087 dbSNP
rs188364770 1092 dbSNP
rs955196474 1095 dbSNP
rs1360762254 1099 dbSNP
rs1171682933 1101 dbSNP
rs144504501 1109 dbSNP
rs1380662057 1114 dbSNP
rs1160127432 1123 dbSNP
rs1449104897 1125 dbSNP
rs1015687438 1134 dbSNP
rs980978063 1136 dbSNP
rs1406638971 1139 dbSNP
rs1181880120 1148 dbSNP
rs1483943684 1149 dbSNP
rs879020720 1150 dbSNP
rs754041888 1151 dbSNP
rs973820030 1155 dbSNP
rs534176908 1158 dbSNP
rs1027820679 1160 dbSNP
rs1241475989 1161 dbSNP
rs1475798283 1167 dbSNP
rs1306394056 1169 dbSNP
rs150623595 1172 dbSNP
rs1357435914 1175 dbSNP
rs561693311 1178 dbSNP
rs928217261 1196 dbSNP
rs1468339125 1200 dbSNP
rs939613317 1204 dbSNP
rs1451197020 1211 dbSNP
rs988126494 1223 dbSNP
rs371061714 1224 dbSNP
rs181316458 1227 dbSNP
rs536627069 1228 dbSNP
rs946819612 1229 dbSNP
rs1043823869 1231 dbSNP
rs904165083 1232 dbSNP
rs1186462598 1235 dbSNP
rs899663042 1238 dbSNP
rs932510475 1241 dbSNP
rs78770054 1248 dbSNP
rs891015529 1249 dbSNP
rs1207194027 1250 dbSNP
rs527365168 1255 dbSNP
rs1015219048 1262 dbSNP
rs890392239 1268 dbSNP
rs1334055279 1270 dbSNP
rs1238340478 1271 dbSNP
rs1009258825 1272 dbSNP
rs1297468205 1277 dbSNP
rs1380369953 1282 dbSNP
rs576598250 1285 dbSNP
rs898192738 1289 dbSNP
rs1280378746 1294 dbSNP
rs1293788117 1296 dbSNP
rs1014756428 1299 dbSNP
rs995244895 1300 dbSNP
rs779746119 1302 dbSNP
rs1425058614 1304 dbSNP
rs149764279 1326 dbSNP
rs969816253 1327 dbSNP
rs565023106 1328 dbSNP
rs1035607603 1333 dbSNP
rs1213636711 1334 dbSNP
rs572391283 1339 dbSNP
rs1192030082 1342 dbSNP
rs1027743310 1351 dbSNP
rs796848536 1352 dbSNP
rs969352375 1353 dbSNP
rs540935812 1355 dbSNP
rs1253054751 1356 dbSNP
rs1180401056 1361 dbSNP
rs1325667966 1364 dbSNP
rs1442666188 1364 dbSNP
rs367620949 1364 dbSNP
rs878947227 1364 dbSNP
rs980779520 1368 dbSNP
rs988839112 1373 dbSNP
rs1230743800 1374 dbSNP
rs1446960153 1374 dbSNP
rs1441121716 1375 dbSNP
rs1171575763 1377 dbSNP
rs1460882959 1380 dbSNP
rs754983629 1385 dbSNP
rs1372896247 1389 dbSNP
rs946748669 1393 dbSNP
rs988840447 1396 dbSNP
rs186839159 1397 dbSNP
rs748096707 1401 dbSNP
rs1304522461 1402 dbSNP
rs769233896 1407 dbSNP
rs921324199 1409 dbSNP
rs968197187 1412 dbSNP
rs529685214 1418 dbSNP
rs1256369531 1423 dbSNP
rs549746717 1429 dbSNP
rs563087003 1430 dbSNP
rs1302300786 1439 dbSNP
rs772727029 1449 dbSNP
rs1232343524 1451 dbSNP
rs539077779 1452 dbSNP
rs1337050145 1457 dbSNP
rs911572679 1459 dbSNP
rs190082690 1474 dbSNP
rs939948805 1479 dbSNP
rs1236877442 1484 dbSNP
rs1437020424 1510 dbSNP
rs1250150786 1511 dbSNP
rs1173277890 1514 dbSNP
rs1037388192 1515 dbSNP
rs1365617906 1519 dbSNP
rs1339253599 1522 dbSNP
rs551563784 1523 dbSNP
rs527456196 1524 dbSNP
rs898145615 1529 dbSNP
rs1212910284 1549 dbSNP
rs1279292678 1553 dbSNP
rs1484592293 1553 dbSNP
rs1240452009 1557 dbSNP
rs1359367703 1565 dbSNP
rs1352325389 1570 dbSNP
rs1277274489 1573 dbSNP
rs995192511 1576 dbSNP
rs114816648 1577 dbSNP
rs1191357314 1580 dbSNP
rs145769220 1582 dbSNP
rs1454563408 1586 dbSNP
rs547801070 1598 dbSNP
rs567942397 1608 dbSNP
rs1374045772 1609 dbSNP
rs560620436 1610 dbSNP
rs1002311002 1611 dbSNP
rs1387499751 1621 dbSNP
rs1035026545 1627 dbSNP
rs1035193054 1633 dbSNP
rs140573134 1636 dbSNP
rs529397948 1644 dbSNP
rs367779602 1655 dbSNP
rs539105659 1658 dbSNP
rs1256562932 1663 dbSNP
rs1461393864 1675 dbSNP
rs1216164218 1677 dbSNP
rs1448517819 1679 dbSNP
rs1009809221 1680 dbSNP
rs770548912 1682 dbSNP
rs1281781453 1685 dbSNP
rs1204152974 1688 dbSNP
rs1021649380 1689 dbSNP
rs1294537551 1692 dbSNP
rs558802595 1693 dbSNP
rs1354040026 1699 dbSNP
rs1438716297 1701 dbSNP
rs1293207343 1708 dbSNP
rs1325488508 1717 dbSNP
rs1431999855 1719 dbSNP
rs766218576 1727 dbSNP
rs538249020 1729 dbSNP
rs1293843587 1737 dbSNP
rs1326406264 1738 dbSNP
rs979584000 1739 dbSNP
rs144404934 1740 dbSNP
rs1228774770 1748 dbSNP
rs541199083 1755 dbSNP
rs921271567 1760 dbSNP
rs1240099330 1761 dbSNP
rs79886713 1765 dbSNP
rs987327971 1771 dbSNP
rs1274508075 1783 dbSNP
rs1211350986 1786 dbSNP
rs1333506235 1789 dbSNP
rs1273161317 1792 dbSNP
rs953115281 1797 dbSNP
rs1341950982 1799 dbSNP
rs17630023 1810 dbSNP
rs1192750432 1820 dbSNP
rs543063440 1823 dbSNP
rs939875811 1824 dbSNP
rs1036930403 1827 dbSNP
rs919815224 1834 dbSNP
rs35030858 1848 dbSNP
rs1044048590 1849 dbSNP
rs1036258114 1857 dbSNP
rs919186946 1858 dbSNP
rs532100270 1859 dbSNP
rs1164246780 1861 dbSNP
rs1395544705 1865 dbSNP
rs1459620415 1868 dbSNP
rs930574001 1873 dbSNP
rs533103585 1876 dbSNP
rs1454545058 1877 dbSNP
rs1254557750 1879 dbSNP
rs868679797 1892 dbSNP
rs146606212 1904 dbSNP
rs781107746 1906 dbSNP
rs761150316 1907 dbSNP
rs1057313845 1922 dbSNP
rs764103473 1923 dbSNP
rs753915625 1928 dbSNP
rs896448180 1934 dbSNP
rs896634360 1936 dbSNP
rs1010000788 1941 dbSNP
rs1349035864 1942 dbSNP
rs1010126274 1950 dbSNP
rs1305964492 1955 dbSNP
rs1232334466 1958 dbSNP
rs1021180834 1968 dbSNP
rs1298758285 1970 dbSNP
rs750452956 1971 dbSNP
rs968260559 1972 dbSNP
rs1223301676 1980 dbSNP
rs1258817112 1985 dbSNP
rs865850503 1986 dbSNP
rs968237196 1990 dbSNP
rs1171398840 2001 dbSNP
rs1453373147 2003 dbSNP
rs1178365114 2006 dbSNP
rs1479371533 2008 dbSNP
rs1001073879 2011 dbSNP
rs757429158 2012 dbSNP
rs954076554 2015 dbSNP
rs559000193 2020 dbSNP
rs73871985 2025 dbSNP
rs912658766 2029 dbSNP
rs1225593278 2034 dbSNP
rs961499914 2036 dbSNP
rs547958896 2040 dbSNP
rs143387131 2041 dbSNP
rs972127106 2049 dbSNP
rs111465107 2052 dbSNP
rs919762948 2056 dbSNP
rs7688500 2064 dbSNP
rs557614198 2068 dbSNP
rs1433720366 2076 dbSNP
rs571868647 2083 dbSNP
rs1414688347 2084 dbSNP
rs1311812592 2093 dbSNP
rs1379261999 2097 dbSNP
rs1406573004 2098 dbSNP
rs1229472535 2100 dbSNP
rs926934033 2107 dbSNP
rs750663190 2125 dbSNP
rs1056818769 2128 dbSNP
rs984740507 2130 dbSNP
rs1483119416 2134 dbSNP
rs754890543 2136 dbSNP
rs937845284 2137 dbSNP
rs781109055 2138 dbSNP
rs1267534069 2140 dbSNP
rs1169939492 2145 dbSNP
rs182097521 2146 dbSNP
rs1357219007 2148 dbSNP
rs748116242 2150 dbSNP
rs1395303638 2151 dbSNP
rs891510085 2154 dbSNP
rs1362374427 2177 dbSNP
rs1290311646 2186 dbSNP
rs1239548432 2190 dbSNP
rs1344102289 2195 dbSNP
rs539021038 2197 dbSNP
rs1009995455 2200 dbSNP
rs1462554197 2210 dbSNP
rs1420723629 2215 dbSNP
rs1042493384 2220 dbSNP
rs1186398759 2227 dbSNP
rs758469765 2232 dbSNP
rs1210068229 2239 dbSNP
rs1188528508 2241 dbSNP
rs1484983092 2243 dbSNP
rs1258055827 2246 dbSNP
rs1247495383 2252 dbSNP
rs1001063750 2254 dbSNP
rs1028560406 2257 dbSNP
rs1484286559 2263 dbSNP
rs903904123 2264 dbSNP
rs1001037646 2265 dbSNP
rs1175507996 2267 dbSNP
rs1407571624 2268 dbSNP
rs1297395200 2271 dbSNP
rs889762941 2272 dbSNP
rs549719182 2276 dbSNP
rs559122526 2277 dbSNP
rs1391611547 2280 dbSNP
rs780597373 2285 dbSNP
rs1008823373 2289 dbSNP
rs1008619112 2290 dbSNP
rs1019621594 2298 dbSNP
rs961723370 2301 dbSNP
rs972883330 2322 dbSNP
rs148201775 2330 dbSNP
rs187142786 2331 dbSNP
rs554711797 2332 dbSNP
rs966168300 2335 dbSNP
rs971877951 2344 dbSNP
rs1194484167 2353 dbSNP
rs1174823556 2354 dbSNP
rs952553430 2378 dbSNP
rs979998493 2392 dbSNP
rs927171580 2398 dbSNP
rs938626336 2400 dbSNP
rs1449621019 2402 dbSNP
rs1252996490 2413 dbSNP
rs951701007 2414 dbSNP
rs1341165496 2421 dbSNP
rs1303741941 2424 dbSNP
rs984668221 2428 dbSNP
rs926545146 2429 dbSNP
rs529199495 2435 dbSNP
rs748773077 2442 dbSNP
rs574649218 2446 dbSNP
rs1300405063 2450 dbSNP
rs912899288 2452 dbSNP
rs1428277125 2455 dbSNP
rs1389914757 2469 dbSNP
rs543675533 2474 dbSNP
rs1345473752 2478 dbSNP
rs1233219033 2486 dbSNP
rs1279274305 2489 dbSNP
rs945783427 2495 dbSNP
rs1393368160 2496 dbSNP
rs191203914 2499 dbSNP
rs1198328441 2503 dbSNP
rs1042820809 2506 dbSNP
rs1232351256 2509 dbSNP
rs548158825 2513 dbSNP
rs1252638569 2532 dbSNP
rs72708344 2541 dbSNP
rs1180743263 2543 dbSNP
rs1482622778 2549 dbSNP
rs903823636 2552 dbSNP
rs140117482 2556 dbSNP
rs1345211965 2558 dbSNP
rs1273878372 2561 dbSNP
rs1049900373 2571 dbSNP
rs890004108 2576 dbSNP
rs1309839889 2579 dbSNP
rs1008484200 2583 dbSNP
rs1370363671 2586 dbSNP
rs1313810858 2590 dbSNP
rs745487851 2595 dbSNP
rs1400400828 2596 dbSNP
rs1436959976 2596 dbSNP
rs772476077 2603 dbSNP
rs1454406083 2604 dbSNP
rs1020033049 2609 dbSNP
rs77836693 2616 dbSNP
rs1020198510 2617 dbSNP
rs1257970409 2652 dbSNP
rs554213411 2653 dbSNP
rs1484560119 2663 dbSNP
rs1027096068 2668 dbSNP
rs528145047 2677 dbSNP
rs1205322998 2687 dbSNP
rs979903883 2689 dbSNP
rs1332962147 2691 dbSNP
rs1437296257 2694 dbSNP
rs182094280 2695 dbSNP
rs1227109549 2698 dbSNP
rs1350338534 2701 dbSNP
rs541268492 2711 dbSNP
rs1439937012 2719 dbSNP
rs960189268 2730 dbSNP
rs185337399 2735 dbSNP
rs1275189799 2739 dbSNP
rs992796613 2743 dbSNP
rs10520345 2744 dbSNP
rs1212726972 2748 dbSNP
rs1272468406 2749 dbSNP
rs1156947967 2752 dbSNP
rs1456771810 2759 dbSNP
rs1318704513 2760 dbSNP
rs1166981705 2763 dbSNP
rs1471712297 2764 dbSNP
rs1200547321 2767 dbSNP
rs1448317491 2770 dbSNP
rs945758647 2771 dbSNP
rs776591621 2777 dbSNP
rs978462421 2780 dbSNP
rs1334892954 2790 dbSNP
rs1468176938 2797 dbSNP
rs368199340 2814 dbSNP
rs550527520 2820 dbSNP
rs1235634840 2826 dbSNP
rs146381813 2836 dbSNP
rs1474750423 2838 dbSNP
rs1431758299 2843 dbSNP
rs992130111 2851 dbSNP
rs1318770544 2854 dbSNP
rs1434530232 2857 dbSNP
rs917736063 2863 dbSNP
rs966570533 2870 dbSNP
rs1403489966 2882 dbSNP
rs1412821189 2889 dbSNP
rs931743459 2894 dbSNP
rs371515179 2898 dbSNP
rs925381148 2898 dbSNP
rs936784308 2898 dbSNP
rs1049698245 2907 dbSNP
rs1254277514 2908 dbSNP
rs911264394 2910 dbSNP
rs1450320595 2912 dbSNP
rs1289786607 2916 dbSNP
rs1215583240 2920 dbSNP
rs1341883703 2927 dbSNP
rs1049847136 2928 dbSNP
rs372281403 2934 dbSNP
rs890002050 2938 dbSNP
rs1371848920 2942 dbSNP
rs1327944714 2943 dbSNP
rs1434223131 2944 dbSNP
rs113868937 2945 dbSNP
rs1460572697 2946 dbSNP
rs1411487128 2947 dbSNP
rs1041306754 2948 dbSNP
rs897278012 2950 dbSNP
rs767730788 2954 dbSNP
rs897129867 2958 dbSNP
rs1189017000 2962 dbSNP
rs1428307042 2964 dbSNP
rs1477400629 2983 dbSNP
rs1269536595 2992 dbSNP
rs1205799898 2994 dbSNP
rs532598697 2997 dbSNP
rs552595875 3009 dbSNP
rs566053102 3016 dbSNP
rs887512652 3032 dbSNP
rs748885130 3042 dbSNP
rs1220583850 3048 dbSNP
rs1348793001 3050 dbSNP
rs1303676981 3051 dbSNP
rs1217606575 3059 dbSNP
rs1006001687 3069 dbSNP
rs1280095677 3073 dbSNP
rs1291485365 3085 dbSNP
rs1048440261 3094 dbSNP
rs1307106864 3096 dbSNP
rs1435099476 3097 dbSNP
rs888498734 3102 dbSNP
rs1210653641 3108 dbSNP
rs959105563 3109 dbSNP
rs1178307541 3111 dbSNP
rs1473826047 3112 dbSNP
rs1013887838 3113 dbSNP
rs111590018 3114 dbSNP
rs966486965 3126 dbSNP
rs977879558 3132 dbSNP
rs190101727 3143 dbSNP
rs1311699699 3151 dbSNP
rs1284973991 3152 dbSNP
rs1034594833 3154 dbSNP
rs1348628708 3160 dbSNP
rs554492022 3166 dbSNP
rs958112508 3171 dbSNP
rs183083748 3172 dbSNP
rs6831342 3173 dbSNP
rs556880811 3177 dbSNP
rs1474716765 3183 dbSNP
rs1163490626 3186 dbSNP
rs1455172053 3190 dbSNP
rs1410480187 3191 dbSNP
rs1159031279 3198 dbSNP
rs1180344694 3203 dbSNP
rs1475754288 3203 dbSNP
rs944056967 3203 dbSNP
rs1483016684 3211 dbSNP
rs1242904461 3212 dbSNP
rs575586950 3214 dbSNP
rs978367673 3229 dbSNP
rs192869558 3232 dbSNP
rs1233771698 3236 dbSNP
rs1323315879 3242 dbSNP
rs556627777 3247 dbSNP
rs953131604 3250 dbSNP
rs1227396898 3252 dbSNP
rs1362291182 3261 dbSNP
rs985878138 3261 dbSNP
rs1361142694 3269 dbSNP
rs1401749115 3277 dbSNP
rs1432307864 3282 dbSNP
rs545401543 3282 dbSNP
rs1311207641 3283 dbSNP
rs1354905484 3287 dbSNP
rs1245537176 3293 dbSNP
rs1286195644 3296 dbSNP
rs930240398 3297 dbSNP
rs556524926 3298 dbSNP
rs888658227 3299 dbSNP
rs183820712 3305 dbSNP
rs368440506 3306 dbSNP
rs918818278 3308 dbSNP
rs1054891444 3314 dbSNP
rs1247450571 3320 dbSNP
rs767447791 3321 dbSNP
rs572872471 3322 dbSNP
rs541874005 3323 dbSNP
rs1307824941 3332 dbSNP
rs1013263823 3340 dbSNP
rs1225684061 3346 dbSNP
rs1257353827 3348 dbSNP
rs561610639 3350 dbSNP
rs999438123 3351 dbSNP
rs1292261320 3353 dbSNP
rs1001612335 3359 dbSNP
rs1371506561 3361 dbSNP
rs1170750402 3362 dbSNP
rs1055912153 3363 dbSNP
rs1389644572 3370 dbSNP
rs1032127483 3374 dbSNP
rs957873483 3383 dbSNP
rs1421216607 3384 dbSNP
rs1171697874 3385 dbSNP
rs895618224 3395 dbSNP
rs1480856629 3396 dbSNP
rs187746327 3404 dbSNP
rs879549366 3405 dbSNP
rs967231643 3408 dbSNP
rs1280596333 3409 dbSNP
rs1000109788 3413 dbSNP
rs1328825486 3416 dbSNP
rs192512068 3417 dbSNP
rs1310175740 3418 dbSNP
rs113492235 3420 dbSNP
rs985828124 3421 dbSNP
rs937497515 3423 dbSNP
rs1467687734 3434 dbSNP
rs911623661 3435 dbSNP
rs1375946819 3439 dbSNP
rs1232481929 3446 dbSNP
rs966200489 3448 dbSNP
rs1253873287 3450 dbSNP
rs976914379 3457 dbSNP
rs894880279 3458 dbSNP
rs949178669 3460 dbSNP
rs918753685 3463 dbSNP
rs1200580767 3473 dbSNP
rs756017956 3475 dbSNP
rs902221313 3476 dbSNP
rs1408426968 3477 dbSNP
rs999364528 3486 dbSNP
rs1335125715 3489 dbSNP
rs1032221305 3491 dbSNP
rs1238346064 3493 dbSNP
rs777822794 3495 dbSNP
rs753715228 3505 dbSNP
rs1048710202 3508 dbSNP
rs909870615 3509 dbSNP
rs188222190 3511 dbSNP
rs1006739172 3512 dbSNP
rs1457833932 3519 dbSNP
rs71613791 3526 dbSNP
rs965474302 3535 dbSNP
rs1472155772 3539 dbSNP
rs895868730 3542 dbSNP
rs559673802 3543 dbSNP
rs528595280 3549 dbSNP
rs745542458 3550 dbSNP
rs951369419 3555 dbSNP
rs771674177 3556 dbSNP
rs1270625827 3563 dbSNP
rs1227037193 3578 dbSNP
rs984335356 3580 dbSNP
rs1000057830 3591 dbSNP
rs1285097030 3592 dbSNP
rs1439207467 3593 dbSNP
rs1032917565 3612 dbSNP
rs1333723074 3614 dbSNP
rs1338998135 3614 dbSNP
rs1435971917 3621 dbSNP
rs377566739 3628 dbSNP
rs1390867659 3632 dbSNP
rs1318495938 3634 dbSNP
rs1303094771 3635 dbSNP
rs889052372 3636 dbSNP
rs1456580405 3643 dbSNP
rs4279153 3647 dbSNP
rs1332233204 3650 dbSNP
rs1236061435 3651 dbSNP
rs1471684341 3652 dbSNP
rs1367571684 3653 dbSNP
rs4582107 3655 dbSNP
rs780403298 3660 dbSNP
rs1250052147 3669 dbSNP
rs548698707 3670 dbSNP
rs72623906 3684 dbSNP
rs1258340916 3687 dbSNP
rs949155697 3695 dbSNP
rs192861778 3706 dbSNP
rs1283847847 3707 dbSNP
rs1019034643 3713 dbSNP
rs184665539 3721 dbSNP
rs1295420021 3722 dbSNP
rs200736461 3724 dbSNP
rs1434446397 3725 dbSNP
rs367657620 3725 dbSNP
rs397996376 3725 dbSNP
rs67194984 3725 dbSNP
rs372203009 3726 dbSNP
rs923568272 3727 dbSNP
rs965785631 3733 dbSNP
rs201139133 3734 dbSNP
rs201904884 3734 dbSNP
rs202078097 3735 dbSNP
rs1168867196 3738 dbSNP
rs540673345 3739 dbSNP
rs972262927 3746 dbSNP
rs1371214801 3750 dbSNP
rs1477551601 3751 dbSNP
rs1187464720 3754 dbSNP
rs1478053319 3758 dbSNP
rs1053243 3763 dbSNP
rs1402785738 3764 dbSNP
rs1460057684 3774 dbSNP
rs1450274409 3780 dbSNP
rs1053603687 3787 dbSNP
rs138013016 3789 dbSNP
rs1206156804 3791 dbSNP
rs1344653452 3799 dbSNP
rs951554440 3807 dbSNP
rs893712440 3809 dbSNP
rs1227814632 3830 dbSNP
rs1132720 3835 dbSNP
rs910110059 3838 dbSNP
rs1276564741 3840 dbSNP
rs937587541 3841 dbSNP
rs991470052 3846 dbSNP
rs1330301680 3848 dbSNP
rs535082036 3848 dbSNP
rs901038035 3852 dbSNP
rs1431399481 3857 dbSNP
rs143519437 3859 dbSNP
rs1025738099 3860 dbSNP
rs1414567574 3862 dbSNP
rs1426614723 3866 dbSNP
rs1278252977 3867 dbSNP
rs1174833106 3868 dbSNP
rs1319631770 3881 dbSNP
rs951338652 3884 dbSNP
rs770012691 3885 dbSNP
rs1042224115 3889 dbSNP
rs575240355 3890 dbSNP
rs1204030277 3891 dbSNP
rs1016969412 3895 dbSNP
rs1264431020 3901 dbSNP
rs1280738992 3902 dbSNP
rs544040108 3903 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 60559.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cauucuucacgaaugUAACGUc 5'
                         |||||| 
Target 5' -----auuuuucuuaAUUGCAa 3'
 		1 - 17
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000503362.1 | 3UTR | AUUUUUCUUAAUUGCAAUAAAUAUUCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer -0.607 8.3e-4 -0.533 3.7e-3 24 Click to see details
GSE21687 Ependynoma primary tumors -0.221 4.0e-2 -0.211 4.7e-2 64 Click to see details
GSE28260 Renal cortex and medulla -0.497 4.2e-2 -0.544 2.7e-2 13 Click to see details
GSE38226 Liver fibrosis 0.361 5.4e-2 0.348 6.1e-2 21 Click to see details
GSE21032 Prostate cancer 0.17 6.2e-2 0.172 6.0e-2 83 Click to see details
GSE26953 Aortic valvular endothelial cells 0.317 6.6e-2 0.242 1.3e-1 24 Click to see details
GSE32688 Pancreatic cancer -0.272 6.6e-2 -0.255 7.9e-2 32 Click to see details
GSE19350 CNS germ cell tumors 0.356 1.3e-1 0.568 2.7e-2 12 Click to see details
GSE42095 Differentiated embryonic stem cells -0.221 1.6e-1 -0.216 1.6e-1 23 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.214 1.8e-1 0.373 5.3e-2 20 Click to see details
GSE17498 Multiple myeloma -0.072 3.3e-1 0.015 4.6e-1 40 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.07 3.7e-1 -0.108 3.0e-1 25 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.136 4.1e-1 0.100 4.4e-1 5 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.136 4.1e-1 0.100 4.4e-1 5 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
KIRP -0.748 0 -0.582 0.02 13 Click to see details
KIRC -0.666 0.05 -0.536 0.11 7 Click to see details
PRAD 0.263 0.06 0.201 0.12 37 Click to see details
LUSC 0.697 0.15 0.200 0.4 4 Click to see details
KICH -0.422 0.29 -0.200 0.4 4 Click to see details
STAD 0.364 0.32 0.800 0.1 4 Click to see details
BRCA 0.112 0.42 0.143 0.39 6 Click to see details
HNSC 0.101 0.44 0.300 0.31 5 Click to see details
LIHC -0.055 0.48 0.500 0.33 3 Click to see details
LIHC -0.055 0.48 0.500 0.33 3 Click to see details
LIHC -0.055 0.48 0.500 0.33 3 Click to see details
LIHC -0.055 0.48 0.500 0.33 3 Click to see details
LIHC -0.055 0.48 0.500 0.33 3 Click to see details
LIHC -0.055 0.48 0.500 0.33 3 Click to see details
162 hsa-miR-106a-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT056049 MLLT10 MLLT10, histone lysine methyltransferase DOT1L cofactor 2 2
MIRT065618 CLIC4 chloride intracellular channel 4 2 4
MIRT071648 DICER1 dicer 1, ribonuclease III 2 4
MIRT081712 ZNF507 zinc finger protein 507 2 2
MIRT093589 SPCS3 signal peptidase complex subunit 3 2 2
MIRT094223 G3BP2 G3BP stress granule assembly factor 2 2 2
MIRT125225 KLHL15 kelch like family member 15 2 6
MIRT169562 PNRC1 proline rich nuclear receptor coactivator 1 2 2
MIRT179227 KMT2A lysine methyltransferase 2A 2 2
MIRT180842 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 2
MIRT248803 SESN2 sestrin 2 2 2
MIRT257843 FAM46A family with sequence similarity 46 member A 2 2
MIRT261799 BUB3 BUB3, mitotic checkpoint protein 2 2
MIRT368750 CDADC1 cytidine and dCMP deaminase domain containing 1 2 2
MIRT448814 FKBP1A FK506 binding protein 1A 2 4
MIRT448950 CDK19 cyclin dependent kinase 19 2 2
MIRT452980 CABP4 calcium binding protein 4 2 2
MIRT454110 MRPL52 mitochondrial ribosomal protein L52 2 2
MIRT456599 CHML CHM like, Rab escort protein 2 2 2
MIRT461652 G6PC glucose-6-phosphatase catalytic subunit 2 2
MIRT464838 RPS27A ribosomal protein S27a 2 12
MIRT469511 RBFOX2 RNA binding protein, fox-1 homolog 2 2 8
MIRT471103 PHLDA2 pleckstrin homology like domain family A member 2 2 2
MIRT475451 HSPA8 heat shock protein family A (Hsp70) member 8 2 6
MIRT478236 DDX3X DEAD-box helicase 3, X-linked 2 4
MIRT480179 CALM2 calmodulin 2 2 8
MIRT481376 ATG12 autophagy related 12 2 2
MIRT495841 PLXDC1 plexin domain containing 1 2 2
MIRT498772 PARP15 poly(ADP-ribose) polymerase family member 15 2 4
MIRT502394 GATA6 GATA binding protein 6 2 8
MIRT504543 ZNF417 zinc finger protein 417 2 6
MIRT504953 ZNRF2 zinc and ring finger 2 2 6
MIRT505044 ZNF226 zinc finger protein 226 2 2
MIRT505285 TRIM66 tripartite motif containing 66 2 6
MIRT508006 BCAT1 branched chain amino acid transaminase 1 2 4
MIRT508372 SPTBN2 spectrin beta, non-erythrocytic 2 2 4
MIRT509026 PALM2-AKAP2 PALM2-AKAP2 readthrough 2 2
MIRT509045 AKAP2 A-kinase anchoring protein 2 2 2
MIRT509640 ZNF354B zinc finger protein 354B 2 10
MIRT512961 KMO kynurenine 3-monooxygenase 2 4
MIRT517859 NCAPD2 non-SMC condensin I complex subunit D2 2 4
MIRT517944 TRIM59 tripartite motif containing 59 2 2
MIRT525900 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 2 2
MIRT529446 SLC28A2 solute carrier family 28 member 2 2 2
MIRT531095 PEX13 peroxisomal biogenesis factor 13 2 2
MIRT534557 RRAS2 RAS related 2 2 2
MIRT537004 GTF2A1 general transcription factor IIA subunit 1 2 2
MIRT538407 COX20 COX20, cytochrome c oxidase assembly factor 2 2
MIRT540635 SUMO1 small ubiquitin-like modifier 1 2 2
MIRT546660 RPS6KA5 ribosomal protein S6 kinase A5 2 2
MIRT547958 HIGD1A HIG1 hypoxia inducible domain family member 1A 2 4
MIRT552022 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT554238 SLBP stem-loop binding protein 2 2
MIRT555287 PPP6R1 protein phosphatase 6 regulatory subunit 1 2 2
MIRT556139 MFF mitochondrial fission factor 2 2
MIRT556419 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT557258 HMGXB4 HMG-box containing 4 2 2
MIRT557318 HIF1A hypoxia inducible factor 1 alpha subunit 2 2
MIRT557774 FRS2 fibroblast growth factor receptor substrate 2 2 2
MIRT559634 AKAP10 A-kinase anchoring protein 10 2 2
MIRT561616 SESN3 sestrin 3 2 2
MIRT566174 PURA purine rich element binding protein A 2 2
MIRT567183 IGFBP5 insulin like growth factor binding protein 5 2 2
MIRT611357 LARP4B La ribonucleoprotein domain family member 4B 2 2
MIRT616553 ZNF512B zinc finger protein 512B 2 2
MIRT617308 FAM9C family with sequence similarity 9 member C 2 2
MIRT624899 AAGAB alpha and gamma adaptin binding protein 2 2
MIRT627008 FIG4 FIG4 phosphoinositide 5-phosphatase 2 2
MIRT627071 SF3A1 splicing factor 3a subunit 1 2 2
MIRT628271 CYB5D1 cytochrome b5 domain containing 1 2 2
MIRT629231 CINP cyclin dependent kinase 2 interacting protein 2 2
MIRT629403 ADM2 adrenomedullin 2 2 2
MIRT629580 RFC2 replication factor C subunit 2 2 2
MIRT629631 WDR31 WD repeat domain 31 2 2
MIRT629796 GPR82 G protein-coupled receptor 82 2 2
MIRT629870 NOM1 nucleolar protein with MIF4G domain 1 2 2
MIRT629916 POLR2D RNA polymerase II subunit D 2 2
MIRT629979 NARS asparaginyl-tRNA synthetase 2 2
MIRT630038 TERF2 telomeric repeat binding factor 2 2 2
MIRT630057 NIP7 NIP7, nucleolar pre-rRNA processing protein 2 2
MIRT630151 ZBTB8A zinc finger and BTB domain containing 8A 2 2
MIRT630245 SMTNL2 smoothelin like 2 2 2
MIRT630274 PSMB5 proteasome subunit beta 5 2 2
MIRT630344 NKAP NFKB activating protein 2 2
MIRT630493 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT631628 ZNF383 zinc finger protein 383 2 2
MIRT632467 RPS15A ribosomal protein S15a 2 2
MIRT632509 RAB11FIP1 RAB11 family interacting protein 1 2 2
MIRT632591 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT632989 DUSP18 dual specificity phosphatase 18 2 2
MIRT633077 CXorf21 chromosome X open reading frame 21 2 2
MIRT635044 MYH11 myosin heavy chain 11 2 2
MIRT636646 CDK4 cyclin dependent kinase 4 2 2
MIRT637185 ROMO1 reactive oxygen species modulator 1 2 2
MIRT637918 LILRA2 leukocyte immunoglobulin like receptor A2 2 2
MIRT642640 PTGR2 prostaglandin reductase 2 2 2
MIRT644231 SLC35E3 solute carrier family 35 member E3 2 2
MIRT644659 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT645084 SLC35E2B solute carrier family 35 member E2B 2 2
MIRT645985 ACP6 acid phosphatase 6, lysophosphatidic 2 2
MIRT646980 SCARB1 scavenger receptor class B member 1 2 2
MIRT647421 ODF4 outer dense fiber of sperm tails 4 2 2
MIRT648322 PLIN1 perilipin 1 2 2
MIRT648506 PIGG phosphatidylinositol glycan anchor biosynthesis class G 2 2
MIRT651460 XIAP X-linked inhibitor of apoptosis 2 2
MIRT656548 LZIC leucine zipper and CTNNBIP1 domain containing 2 2
MIRT657371 HMGB1 high mobility group box 1 2 2
MIRT660828 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT660916 ADAM19 ADAM metallopeptidase domain 19 2 2
MIRT661232 ARL17B ADP ribosylation factor like GTPase 17B 2 2
MIRT662840 OMD osteomodulin 2 2
MIRT662902 MED18 mediator complex subunit 18 2 2
MIRT663518 MASTL microtubule associated serine/threonine kinase like 2 2
MIRT663537 CCR6 C-C motif chemokine receptor 6 2 2
MIRT664345 C16orf45 chromosome 16 open reading frame 45 2 2
MIRT666074 SSTR2 somatostatin receptor 2 2 2
MIRT667219 NFE2L1 nuclear factor, erythroid 2 like 1 2 2
MIRT667756 KDELR1 KDEL endoplasmic reticulum protein retention receptor 1 2 2
MIRT668647 DYM dymeclin 2 2
MIRT671471 FLYWCH2 FLYWCH family member 2 2 2
MIRT671488 SLC38A9 solute carrier family 38 member 9 2 2
MIRT671917 PLEKHS1 pleckstrin homology domain containing S1 2 4
MIRT672285 GP2 glycoprotein 2 2 2
MIRT674022 ANKRD9 ankyrin repeat domain 9 2 2
MIRT674212 FAM120AOS family with sequence similarity 120A opposite strand 2 2
MIRT674510 PRR23A proline rich 23A 2 2
MIRT675095 SNTB2 syntrophin beta 2 2 2
MIRT675261 ZNF431 zinc finger protein 431 2 2
MIRT680630 KIAA1456 KIAA1456 2 2
MIRT681609 F2RL2 coagulation factor II thrombin receptor like 2 2 2
MIRT681919 KAT7 lysine acetyltransferase 7 2 2
MIRT682042 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT682055 B4GALT7 beta-1,4-galactosyltransferase 7 2 4
MIRT683756 CPE carboxypeptidase E 2 2
MIRT690233 CENPK centromere protein K 2 2
MIRT699167 SMAD2 SMAD family member 2 2 2
MIRT699905 RUNDC1 RUN domain containing 1 2 2
MIRT704401 CTPS1 CTP synthase 1 2 2
MIRT706252 MKLN1 muskelin 1 2 2
MIRT708876 MOCS2 molybdenum cofactor synthesis 2 2 2
MIRT710788 IFNLR1 interferon lambda receptor 1 2 2
MIRT711947 SLC7A14 solute carrier family 7 member 14 2 2
MIRT712587 ADCYAP1 adenylate cyclase activating polypeptide 1 2 2
MIRT713335 KLRD1 killer cell lectin like receptor D1 2 2
MIRT713901 IGF2R insulin like growth factor 2 receptor 2 2
MIRT714079 ZNF532 zinc finger protein 532 2 2
MIRT714881 GOLPH3 golgi phosphoprotein 3 2 2
MIRT715190 FKTN fukutin 2 2
MIRT717798 FAM114A1 family with sequence similarity 114 member A1 2 2
MIRT721434 ARPC4 actin related protein 2/3 complex subunit 4 2 2
MIRT722777 PDE3A phosphodiesterase 3A 2 2
MIRT723415 FAM208B family with sequence similarity 208 member B 2 2
MIRT732545 AURKA aurora kinase A 1 0
MIRT732549 MYCN MYCN proto-oncogene, bHLH transcription factor 1 0
MIRT733122 YAP1 Yes associated protein 1 3 0
MIRT733238 VEGFA vascular endothelial growth factor A 1 0
MIRT733725 TGFB1 transforming growth factor beta 1 2 0
MIRT733728 NOTCH1 notch 1 2 0
MIRT733829 RUNX2 runt related transcription factor 2 1 0
MIRT733830 BMP2 bone morphogenetic protein 2 1 0
MIRT736953 SMAD7 SMAD family member 7 3 0
MIRT737029 FOXQ1 forkhead box Q1 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-106a Cisplatin approved 84093 Quantitative real-time PCR ovarian cancer cells 24348845 2014 up-regulated
miR-106a Cisplatin approved 84093 Microarray ovarian cancer 19237188 2009 down-regulated
miR-106a Vorinostat (SAHA) approved 5311 Microarray A549 human non-small cell lung cancer cells 19513533 2009 down-regulated
miR-106a Diethylstilbestrol approved 448537 Microarray mammosphere-derived epithelial cells (MDEC) 19549897 2009 down-regulated
miR-106a Diethylstilbestrol approved 448537 Quantitative real-time PCR mammosphere-derived epithelial cells (MDEC) 19549897 2009 down-regulated
miR-106a 5-Fluorouracil approved 3385 Microarray HCT-8 colon cancer cell line 19956872 2010 down-regulated
miR-106a Bisphenol A NULL 6623 Microarray immortalized cytotrophoblast cell lines HTR-8 20417706 2010 up-regulated
miR-106a Formaldehyde NULL 712 Microarray Human lung epithelial cells (A549) 21147603 2011 down-regulated
miR-106a Bicalutamide approved 2375 Microarray prostate 22674191 2012 down-regulated
miR-106a Narangin NULL 442428 Microarray apoE−/− mice 22253797 2012 up-regulated
miR-106a Tamoxifen approved 2733526 Microarray rat liver 17343880 2007 up-regulated
miR-106a Tamoxifen approved 2733526 Quantitative real-time PCR rat liver 17343880 2007 up-regulated
miR-106a 17beta-estradiol (E2) approved 5757 Microarray rat breast 17700064 2007 up-regulated
miR-106a 17beta-estradiol (E2) approved 5757 Quantitative real-time PCR rat breast 17700064 2007 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-106a-3p Docetaxel 148124 NSC628503 approved resistant High Breast Cancer cell line (BT-20, BT-474, BT-549, CAMA-1, HCC1143, HCC1395, HCC1569, HCC1806, HCC-1937, HCC1954, HCC202, HCC38, HCC70, Hs578T, MCF-7, MDA-MB-175VII, MDA-MB-231, MDA-MB-361, MDA-MB-415, MDA-MB-436, MDA-MB-468, SKBR3, T47D, UACC812, EVSA-T, MPE-600 , SK-BR-
hsa-miR-106a-3p Paclitaxel 36314 NSC125973 approved resistant High Breast Cancer cell line (BT-20, BT-474, BT-549, CAMA-1, HCC1143, HCC1395, HCC1569, HCC1806, HCC-1937, HCC1954, HCC202, HCC38, HCC70, Hs578T, MCF-7, MDA-MB-175VII, MDA-MB-231, MDA-MB-361, MDA-MB-415, MDA-MB-436, MDA-MB-468, SKBR3, T47D, UACC812, EVSA-T, MPE-600 , SK-BR-
hsa-miR-106a-3p Apatinib 11315474 NSC772886 resistant Low Gastric Cancer cell line (SGC-7901)
hsa-miR-106a-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-106a-3p Cisplatin 5460033 NSC119875 approved resistant cell line (IGROV-1)
hsa-miR-106a-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-106a-3p Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-106a-3p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)

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