miRTarBase - #MIRT095408


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pre-miRNA Information
pre-miRNA hsa-mir-548aq   
Genomic Coordinates chr3: 185767847 - 185767904
Description Homo sapiens miR-548aq stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-548aq-5p
Sequence 1| GAAAGUAAUUGCUGUUUUUGCC |22
Evidence Not_experimental
Experiments
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 7 3 - 185767898 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs148741643 4 dbSNP
rs373424261 5 dbSNP
rs954388082 9 dbSNP
rs1008952958 10 dbSNP
rs1443286362 15 dbSNP
rs778852684 17 dbSNP
rs1042518237 21 dbSNP
rs1299293460 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol UBE2D2   
Synonyms E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH4, UBCH5B
Description ubiquitin conjugating enzyme E2 D2
Transcript NM_003339   
Other Transcripts NM_181838   
Expression
Putative miRNA Targets on UBE2D2
3'UTR of UBE2D2
(miRNA target sites are highlighted)		 
>UBE2D2|NM_003339|3'UTR
   1 TTAAAGAAATTATTGGATAACCTCTACAAATAAAGATAGGGGAACTCTGAAAGAGAAAGTCCTTTTGATTTCCATTTGAC
  81 TGCTTTCTATGAGCCCACGCCTCATCTTCCCCTGTGCACATGTTTACCTGATACAGCAGTGCTGCGTGTTGTACATACTT
 161 GGAACAACAAACTAGAAATACTGTACTTCTGTACCAACATTGCCTCCTAGCAGAGAAGTGTGTGTGTGACAAGCCAGTTC
 241 TACAGGCATTACCTAGGTGTGAGACTAAAAGCTTTTCTTATTGACTTAAATTTGGATAACAGCAAGGTGTGAGGGGGGTG
 321 GTGGGTATGGTGTGTGCTTGGATGGGAAAGAAAAGGCTCCACTCACCTATAGGAGATTATTTTTAAGTGGAATCCATTTA
 401 AACTCAAAACAGTTATGAAAAGCAAGGTGAAGAACATGAAGCTGTGTCTGTATTCATTTTATTCCGAAGGAGCTACGTCT
 481 TAGGTGAAAGTTATGACCAACCAGATTAAACTCTACCCACATCCTGCATTTTAAGGTCTAAGTTTAACTGGTCAACATTT
 561 AAATGGATTGGAGCTATTAGTACATCAAGTGTGATGGGCTTTGTTCCCAACTCTTTTACATCTCCCTACCCCTTCAACCT
 641 TTGGCCTTTCAGCCCTTCTTTCTCTCTTCCATATTCTTTGGTTTGTATGTGGTTTCTCAGTTAATACATAGCTAATAGCT
 721 CTTATTTTTCTTATGTTTTTAACCGCTTAGGTCTATTTGGATGTAAGGGTGAAAATTCATTTGATGGAAATACTTGTGTA
 801 TATTTAAAGACCCAATTGCTCCTCTGGAGCTTGTACTTTCAAGAATGATTAATCTGTGTAATAAACTGGTTACTACAGTC
 881 ATTACATATAATTTTGTGTGAATAGGCTTTTTCATTTTTAAGAAGTTTGTCTAGCTGAGATTAGTGGTGGATTTTCTCCC
 961 ACTTCTGAAATGTTCATTTATACTGGTTGCATTTTAAGATCATGAAACAATTCCAGTTACATTGTAAAAAGGATATCTTA
1041 CGAGTAATTTTATTGAACAAGTTAGAGGCATAAGCTTAAGAGCATTTCCATGAAACAACACATGCAGCATTCCAGGAACT
1121 TGATTGTTAAATTCAATAAGAAATTTGCTTTATTAATGAAACTAAGCTGCATTTCATCAAAACCTTGTGACATTCCCTTG
1201 GTACATAGGACATAAAACACAGAGGCATTGCTATTTGGTAAGTTAAGCTTCTGTGATTGTAATTATAAAAGAGCAACATT
1281 GACCAAACCTGGGAAACAAGAGCACAGTCTTGTTTGGAGAGTCTACATAATTACTTTGCACTAACATTTGCAGGATGTTC
1361 ACACAATTTTAAATTGTACTGTATGTGGCTTTTTGAAGTCTTCCCTTGACCCTAGTAAAATATAGCTTGAAACTTGTAAA
1441 CAACTGTGTTTGCCAGAAACATCATTCATGTGAACTAGGCAAGTTACCTTTTTTCCCCCCTTCTTTTCCTAATTGTAAAC
1521 TAGGCCAACCTGAAAGCCATGGCTGATGCTCTAGCCATCAGGTTCTTTCAAATGCATCTTTACACTCTTGCACAAAAGTT
1601 AAGGAATAAATGTCCACTGCTTTTGGTTTTAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ccguuuuUGUCGUUAAUGAAAg 5'
                 ||| :||||||||| 
Target 5' agagtctACA-TAATTACTTTg 3'
 1318 - 1338 158.00 -7.50
2 
miRNA  3' ccguuuUUGUCGUUAAUGAAAg 5'
                ||:|||  |||:||| 
Target 5' atagctAATAGCTCTTATTTTt 3'
 708 - 729 144.00 -10.20
3 
miRNA  3' ccGUUUUUGUCGU-UAAUGAAAg 5'
            ||   |:|| | ||||:||| 
Target 5' ctCACCTATAGGAGATTATTTTt 3'
 362 - 384 140.00 -7.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30123995 7 COSMIC
COSN30486880 23 COSMIC
COSN30374502 42 COSMIC
COSN30524814 50 COSMIC
COSN30495618 59 COSMIC
COSN30104649 62 COSMIC
COSN30462725 62 COSMIC
COSN30462726 63 COSMIC
COSN31494452 75 COSMIC
COSN19555056 90 COSMIC
COSN26556235 100 COSMIC
COSN31554357 142 COSMIC
COSN25991948 146 COSMIC
COSN30168383 169 COSMIC
COSN31486262 284 COSMIC
COSN26641350 317 COSMIC
COSN26708874 467 COSMIC
COSN31567591 546 COSMIC
COSN31962468 608 COSMIC
COSN31544684 754 COSMIC
COSN27021299 862 COSMIC
COSN16351941 964 COSMIC
COSN16706519 1062 COSMIC
COSN9408105 1127 COSMIC
COSN31480258 1135 COSMIC
COSN31480279 1252 COSMIC
COSN31606704 1330 COSMIC
COSN26641888 1437 COSMIC
COSN26261376 1496 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1052679743 3 dbSNP
rs1457836916 7 dbSNP
rs1354346377 12 dbSNP
rs893466029 16 dbSNP
rs1010544532 17 dbSNP
rs752811260 18 dbSNP
rs760235447 22 dbSNP
rs756302927 30 dbSNP
rs1374175700 32 dbSNP
rs774461241 38 dbSNP
rs777993785 41 dbSNP
rs1320522384 43 dbSNP
rs1219297928 46 dbSNP
rs1191916905 56 dbSNP
rs763748835 57 dbSNP
rs1337296348 62 dbSNP
rs1039508757 71 dbSNP
rs1399828833 81 dbSNP
rs1341477485 89 dbSNP
rs866982409 90 dbSNP
rs1269571970 91 dbSNP
rs1389399508 97 dbSNP
rs754387867 99 dbSNP
rs762452641 100 dbSNP
rs867329104 105 dbSNP
rs1169462723 108 dbSNP
rs1054528193 110 dbSNP
rs1425426453 120 dbSNP
rs888750670 120 dbSNP
rs1451033046 122 dbSNP
rs943048602 129 dbSNP
rs141996427 132 dbSNP
rs1029486368 142 dbSNP
rs1469853637 146 dbSNP
rs951215023 152 dbSNP
rs1040073316 166 dbSNP
rs1319051861 179 dbSNP
rs1161087254 182 dbSNP
rs1272224821 195 dbSNP
rs1231530177 198 dbSNP
rs554505544 203 dbSNP
rs1331097537 205 dbSNP
rs1343429205 206 dbSNP
rs111318549 218 dbSNP
rs1397435871 221 dbSNP
rs1016810563 224 dbSNP
rs998295263 239 dbSNP
rs1465755041 244 dbSNP
rs1025844687 260 dbSNP
rs963715439 265 dbSNP
rs1170654126 268 dbSNP
rs1477561060 273 dbSNP
rs973367561 277 dbSNP
rs1378171351 278 dbSNP
rs1023714341 282 dbSNP
rs1369131525 283 dbSNP
rs1236371036 287 dbSNP
rs1198256428 293 dbSNP
rs543471835 297 dbSNP
rs1402511356 301 dbSNP
rs1199150533 305 dbSNP
rs1344720107 310 dbSNP
rs1282288555 312 dbSNP
rs1237066828 316 dbSNP
rs1350707885 317 dbSNP
rs1374016536 319 dbSNP
rs1307976672 329 dbSNP
rs1446865391 330 dbSNP
rs750809326 333 dbSNP
rs982133373 336 dbSNP
rs1005761535 344 dbSNP
rs1017611759 348 dbSNP
rs758586272 350 dbSNP
rs928140997 356 dbSNP
rs556818387 357 dbSNP
rs1413728483 363 dbSNP
rs758497521 368 dbSNP
rs191050466 371 dbSNP
rs991504574 373 dbSNP
rs564761190 376 dbSNP
rs1024376123 387 dbSNP
rs750198917 393 dbSNP
rs915489459 397 dbSNP
rs1379611571 411 dbSNP
rs1178174959 415 dbSNP
rs1316635407 417 dbSNP
rs1185645347 428 dbSNP
rs531531608 439 dbSNP
rs1442218354 449 dbSNP
rs146304610 454 dbSNP
rs1279696324 456 dbSNP
rs1213456508 457 dbSNP
rs1352221399 464 dbSNP
rs527986773 466 dbSNP
rs971501203 467 dbSNP
rs1267711361 470 dbSNP
rs1487568125 477 dbSNP
rs1198759380 478 dbSNP
rs1252881822 484 dbSNP
rs946407038 487 dbSNP
rs977650858 492 dbSNP
rs924508847 496 dbSNP
rs1180202874 498 dbSNP
rs1314565975 511 dbSNP
rs1405539227 513 dbSNP
rs1039371242 527 dbSNP
rs374966542 539 dbSNP
rs768909287 539 dbSNP
rs899614814 550 dbSNP
rs1422270731 555 dbSNP
rs1410176921 556 dbSNP
rs138185765 561 dbSNP
rs1350803873 575 dbSNP
rs1472628301 589 dbSNP
rs1411288002 599 dbSNP
rs561292689 607 dbSNP
rs375733585 614 dbSNP
rs369111773 615 dbSNP
rs990051670 623 dbSNP
rs10241 624 dbSNP
rs1050840345 627 dbSNP
rs1487494413 629 dbSNP
rs1263139225 651 dbSNP
rs1217927868 661 dbSNP
rs886942419 663 dbSNP
rs1318213089 668 dbSNP
rs1287049706 672 dbSNP
rs531726045 673 dbSNP
rs1294724259 674 dbSNP
rs1216618970 678 dbSNP
rs751819319 680 dbSNP
rs1339557341 686 dbSNP
rs1298759701 688 dbSNP
rs1315492318 707 dbSNP
rs755027461 719 dbSNP
rs1321728539 722 dbSNP
rs1357906680 729 dbSNP
rs1221926331 735 dbSNP
rs1275449045 736 dbSNP
rs1167320139 743 dbSNP
rs550219462 745 dbSNP
rs1423286109 746 dbSNP
rs1487175821 756 dbSNP
rs943017322 762 dbSNP
rs1442887483 766 dbSNP
rs898414419 780 dbSNP
rs994821505 784 dbSNP
rs923015211 785 dbSNP
rs1469475928 798 dbSNP
rs929095534 799 dbSNP
rs1278675542 801 dbSNP
rs373752044 816 dbSNP
rs1365460644 817 dbSNP
rs1053439 819 dbSNP
rs1415950770 820 dbSNP
rs1435888598 841 dbSNP
rs1395244278 853 dbSNP
rs1464206239 855 dbSNP
rs757469340 855 dbSNP
rs532216831 861 dbSNP
rs1399832734 862 dbSNP
rs1162782497 866 dbSNP
rs969337429 875 dbSNP
rs887247257 877 dbSNP
rs982165491 881 dbSNP
rs1326486919 887 dbSNP
rs1454353194 889 dbSNP
rs376914117 890 dbSNP
rs565643404 907 dbSNP
rs536506228 910 dbSNP
rs894752839 915 dbSNP
rs1449288773 923 dbSNP
rs1251501163 930 dbSNP
rs957128313 933 dbSNP
rs1310176136 936 dbSNP
rs547893957 937 dbSNP
rs781306479 945 dbSNP
rs988326116 952 dbSNP
rs1305807391 961 dbSNP
rs915504574 966 dbSNP
rs1245901939 992 dbSNP
rs998911081 1005 dbSNP
rs1298932547 1006 dbSNP
rs1298926202 1011 dbSNP
rs1463884079 1018 dbSNP
rs1344446829 1022 dbSNP
rs1032183906 1024 dbSNP
rs1397414071 1028 dbSNP
rs946941385 1031 dbSNP
rs369245200 1042 dbSNP
rs1438505472 1043 dbSNP
rs536622474 1050 dbSNP
rs1178526305 1051 dbSNP
rs990409191 1052 dbSNP
rs79958203 1055 dbSNP
rs1211328321 1062 dbSNP
rs1051295082 1066 dbSNP
rs1350037613 1069 dbSNP
rs1283771753 1081 dbSNP
rs1238110080 1096 dbSNP
rs577003100 1101 dbSNP
rs1353029955 1103 dbSNP
rs1210640992 1112 dbSNP
rs539286216 1125 dbSNP
rs1308010439 1128 dbSNP
rs1393304582 1138 dbSNP
rs554360700 1149 dbSNP
rs1302690514 1156 dbSNP
rs939887388 1157 dbSNP
rs1415754896 1164 dbSNP
rs1377836185 1175 dbSNP
rs770916398 1179 dbSNP
rs1038186991 1187 dbSNP
rs910453146 1197 dbSNP
rs898446979 1198 dbSNP
rs1160844472 1199 dbSNP
rs1421754704 1207 dbSNP
rs1255031105 1208 dbSNP
rs1012804980 1211 dbSNP
rs1188452683 1215 dbSNP
rs144379658 1224 dbSNP
rs183095371 1226 dbSNP
rs905211161 1227 dbSNP
rs1390673018 1234 dbSNP
rs13359150 1241 dbSNP
rs1261322147 1247 dbSNP
rs1241252818 1249 dbSNP
rs1165635010 1258 dbSNP
rs1035555622 1259 dbSNP
rs1418433957 1260 dbSNP
rs1414685755 1261 dbSNP
rs1335716939 1269 dbSNP
rs956796343 1270 dbSNP
rs1452323840 1280 dbSNP
rs922899196 1285 dbSNP
rs1321853661 1290 dbSNP
rs1234315157 1299 dbSNP
rs1357702449 1303 dbSNP
rs928969960 1303 dbSNP
rs1399863369 1304 dbSNP
rs1386308109 1305 dbSNP
rs1010180559 1308 dbSNP
rs1290179607 1321 dbSNP
rs1455914675 1322 dbSNP
rs747322202 1326 dbSNP
rs561145029 1328 dbSNP
rs1165149068 1331 dbSNP
rs576409992 1335 dbSNP
rs1476079837 1336 dbSNP
rs1367948438 1343 dbSNP
rs1192866232 1348 dbSNP
rs1022486952 1350 dbSNP
rs778524336 1353 dbSNP
rs1186598907 1363 dbSNP
rs941519266 1384 dbSNP
rs968182779 1386 dbSNP
rs200672651 1396 dbSNP
rs1272807832 1403 dbSNP
rs1269672728 1423 dbSNP
rs531859399 1437 dbSNP
rs1227134999 1444 dbSNP
rs771805075 1447 dbSNP
rs894723555 1449 dbSNP
rs1298333397 1461 dbSNP
rs781295934 1475 dbSNP
rs1384602103 1494 dbSNP
rs1326188119 1495 dbSNP
rs1462636459 1495 dbSNP
rs550322884 1495 dbSNP
rs1221173356 1499 dbSNP
rs955058197 1500 dbSNP
rs1169754737 1504 dbSNP
rs1475598868 1513 dbSNP
rs1374752978 1515 dbSNP
rs986479506 1516 dbSNP
rs1196596410 1517 dbSNP
rs1431523673 1519 dbSNP
rs1013214588 1526 dbSNP
rs1261447116 1530 dbSNP
rs1321201376 1536 dbSNP
rs1202767629 1545 dbSNP
rs908311674 1548 dbSNP
rs1366436195 1552 dbSNP
rs543445664 1553 dbSNP
rs1448655732 1562 dbSNP
rs565085434 1563 dbSNP
rs1241030862 1564 dbSNP
rs1195627504 1569 dbSNP
rs1340449119 1572 dbSNP
rs866788227 1574 dbSNP
rs1231640637 1575 dbSNP
rs1369621810 1582 dbSNP
rs907168342 1586 dbSNP
rs1178181524 1596 dbSNP
rs775262976 1598 dbSNP
rs551955130 1610 dbSNP
rs1442453120 1613 dbSNP
rs1129294 1617 dbSNP
rs999278076 1627 dbSNP
rs1327715686 1631 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 7322.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ccguuuuUGUCGUUAAUGAAAg 5'
                 ||| :||||||||| 
Target 5' ----ucuACA-UAAUUACUUUg 3'
 		1 - 17
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000398733.3 | 3UTR | UCUACAUAAUUACUUUGCACUAACAUUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
184 hsa-miR-548aq-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT057134 DDIT4 DNA damage inducible transcript 4 2 4
MIRT063382 ETNK1 ethanolamine kinase 1 2 2
MIRT072505 RAB8B RAB8B, member RAS oncogene family 2 2
MIRT082197 ACTN4 actinin alpha 4 2 6
MIRT083047 PTBP1 polypyrimidine tract binding protein 1 2 2
MIRT085199 SLC5A3 solute carrier family 5 member 3 2 4
MIRT088917 FOXN2 forkhead box N2 2 4
MIRT089509 MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 6
MIRT092051 ABHD5 abhydrolase domain containing 5 2 2
MIRT094694 FEM1C fem-1 homolog C 2 2
MIRT095408 UBE2D2 ubiquitin conjugating enzyme E2 D2 2 2
MIRT096514 BRIX1 BRX1, biogenesis of ribosomes 2 2
MIRT101306 FAM135A family with sequence similarity 135 member A 2 2
MIRT103369 CBX3 chromobox 3 2 2
MIRT103887 FOXK1 forkhead box K1 2 2
MIRT104347 CLDN12 claudin 12 2 2
MIRT104511 PEG10 paternally expressed 10 2 6
MIRT111811 MPZL1 myelin protein zero like 1 2 2
MIRT177250 BMI1 BMI1 proto-oncogene, polycomb ring finger 2 2
MIRT177285 COMMD3-BMI1 COMMD3-BMI1 readthrough 2 2
MIRT177635 UBE2D1 ubiquitin conjugating enzyme E2 D1 2 6
MIRT178051 SAMD8 sterile alpha motif domain containing 8 2 2
MIRT179111 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 6
MIRT179598 CAPZA1 capping actin protein of muscle Z-line alpha subunit 1 2 6
MIRT195309 LEPROT leptin receptor overlapping transcript 2 2
MIRT203155 BACH1 BTB domain and CNC homolog 1 2 2
MIRT208439 ZBTB38 zinc finger and BTB domain containing 38 2 2
MIRT214587 SMAD5 SMAD family member 5 2 4
MIRT216114 IL6ST interleukin 6 signal transducer 2 2
MIRT216366 CCNB1 cyclin B1 2 4
MIRT220062 MDFIC MyoD family inhibitor domain containing 2 2
MIRT226739 ANP32B acidic nuclear phosphoprotein 32 family member B 2 4
MIRT227708 TBC1D13 TBC1 domain family member 13 2 2
MIRT230083 SH3BGRL SH3 domain binding glutamate rich protein like 2 2
MIRT248647 HMGN2 high mobility group nucleosomal binding domain 2 2 4
MIRT254803 XRCC6 X-ray repair cross complementing 6 2 6
MIRT264390 YAP1 Yes associated protein 1 2 2
MIRT266985 LRRC55 leucine rich repeat containing 55 2 4
MIRT273960 SPRYD4 SPRY domain containing 4 2 2
MIRT281812 MAP2K1 mitogen-activated protein kinase kinase 1 2 2
MIRT293265 DR1 down-regulator of transcription 1 2 2
MIRT297107 RGPD4 RANBP2-like and GRIP domain containing 4 2 2
MIRT308184 PDE12 phosphodiesterase 12 2 2
MIRT309027 USP53 ubiquitin specific peptidase 53 2 2
MIRT311481 PRRC1 proline rich coiled-coil 1 2 2
MIRT312599 G3BP1 G3BP stress granule assembly factor 1 2 4
MIRT328139 ZNF711 zinc finger protein 711 2 2
MIRT329324 FAM53C family with sequence similarity 53 member C 2 2
MIRT334652 NEK7 NIMA related kinase 7 2 2
MIRT340683 THRAP3 thyroid hormone receptor associated protein 3 2 2
MIRT378867 ITGB8 integrin subunit beta 8 2 2
MIRT395804 SPCS3 signal peptidase complex subunit 3 2 2
MIRT405650 WBP4 WW domain binding protein 4 2 4
MIRT408296 GRPEL2 GrpE like 2, mitochondrial 2 2
MIRT442110 ZNRF2 zinc and ring finger 2 2 8
MIRT442853 GTF2H5 general transcription factor IIH subunit 5 2 2
MIRT443129 VLDLR very low density lipoprotein receptor 2 2
MIRT443160 ZDHHC21 zinc finger DHHC-type containing 21 2 2
MIRT443311 PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1 2 2
MIRT445093 ZNF207 zinc finger protein 207 2 2
MIRT445397 PTCHD1 patched domain containing 1 2 4
MIRT447083 MCC mutated in colorectal cancers 2 2
MIRT447313 ZNF562 zinc finger protein 562 2 2
MIRT447526 MRPS5 mitochondrial ribosomal protein S5 2 2
MIRT449524 TM6SF1 transmembrane 6 superfamily member 1 2 2
MIRT449915 C11orf34 placenta expressed transcript 1 1 2
MIRT450564 SHFM1 SEM1, 26S proteasome complex subunit 2 2
MIRT450732 PVRL3 nectin cell adhesion molecule 3 2 2
MIRT454936 ANKEF1 ankyrin repeat and EF-hand domain containing 1 2 12
MIRT455905 KIF2C kinesin family member 2C 2 2
MIRT463745 YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon 2 8
MIRT471195 PHB2 prohibitin 2 2 2
MIRT472777 MTMR6 myotubularin related protein 6 2 8
MIRT474470 KLHL11 kelch like family member 11 2 8
MIRT475998 GTPBP2 GTP binding protein 2 2 2
MIRT482290 AGO2 argonaute 2, RISC catalytic component 2 4
MIRT485871 ALG9 ALG9, alpha-1,2-mannosyltransferase 2 2
MIRT486205 ERH ERH, mRNA splicing and mitosis factor 2 4
MIRT488622 FAM3C family with sequence similarity 3 member C 2 6
MIRT489997 DDB1 damage specific DNA binding protein 1 2 2
MIRT493489 IPMK inositol polyphosphate multikinase 2 2
MIRT494293 CEP120 centrosomal protein 120 2 2
MIRT498005 ZBTB20 zinc finger and BTB domain containing 20 2 2
MIRT498486 PTBP2 polypyrimidine tract binding protein 2 2 10
MIRT498572 TMEM30B transmembrane protein 30B 2 2
MIRT499880 SVOP SV2 related protein 2 10
MIRT500233 INHBA inhibin beta A subunit 2 10
MIRT500707 TRIM37 tripartite motif containing 37 2 2
MIRT501001 SPPL2A signal peptide peptidase like 2A 2 4
MIRT501036 SMG1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 2 6
MIRT502749 CLIP1 CAP-Gly domain containing linker protein 1 2 8
MIRT502811 CELSR3 cadherin EGF LAG seven-pass G-type receptor 3 2 6
MIRT502900 CDK4 cyclin dependent kinase 4 2 8
MIRT503496 ZNF154 zinc finger protein 154 2 6
MIRT503730 GRM5 glutamate metabotropic receptor 5 2 2
MIRT505150 YOD1 YOD1 deubiquitinase 2 2
MIRT505815 RSBN1 round spermatid basic protein 1 2 8
MIRT505854 POLR1B RNA polymerase I subunit B 2 4
MIRT509297 NPM3 nucleophosmin/nucleoplasmin 3 2 6
MIRT516842 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT520532 TRA2B transformer 2 beta homolog 2 2
MIRT520736 TM9SF3 transmembrane 9 superfamily member 3 2 6
MIRT525416 SHISA9 shisa family member 9 2 4
MIRT525880 ARL13B ADP ribosylation factor like GTPase 13B 2 2
MIRT526026 RBM4B RNA binding motif protein 4B 2 2
MIRT526097 TMEM41B transmembrane protein 41B 2 2
MIRT527944 FRY FRY microtubule binding protein 2 2
MIRT528831 RAB32 RAB32, member RAS oncogene family 2 2
MIRT531075 SLC9A4 solute carrier family 9 member A4 2 4
MIRT535508 PANX1 pannexin 1 2 2
MIRT536695 IKZF5 IKAROS family zinc finger 5 2 2
MIRT536848 HMBOX1 homeobox containing 1 2 2
MIRT537215 GDE1 glycerophosphodiester phosphodiesterase 1 2 4
MIRT537847 EFNA5 ephrin A5 2 2
MIRT538358 CSE1L chromosome segregation 1 like 2 4
MIRT541255 GPC4 glypican 4 2 2
MIRT543248 PEX7 peroxisomal biogenesis factor 7 2 2
MIRT543463 PARP15 poly(ADP-ribose) polymerase family member 15 2 2
MIRT543724 XKR9 XK related 9 2 2
MIRT543920 ESYT1 extended synaptotagmin 1 2 2
MIRT544012 KLRC3 killer cell lectin like receptor C3 2 2
MIRT544083 METTL8 methyltransferase like 8 2 2
MIRT544200 ANGPTL3 angiopoietin like 3 2 2
MIRT544821 ACSM2B acyl-CoA synthetase medium chain family member 2B 2 2
MIRT545059 PRELID1 PRELI domain containing 1 2 2
MIRT545227 HIST1H2BD histone cluster 1 H2B family member d 2 2
MIRT545302 SPC25 SPC25, NDC80 kinetochore complex component 2 2
MIRT545563 GIMAP4 GTPase, IMAP family member 4 2 2
MIRT546510 SIK1 salt inducible kinase 1 2 2
MIRT546927 PTP4A1 protein tyrosine phosphatase type IVA, member 1 2 2
MIRT547688 KPNA1 karyopherin subunit alpha 1 2 4
MIRT547781 KATNAL1 katanin catalytic subunit A1 like 1 2 2
MIRT548700 CRNKL1 crooked neck pre-mRNA splicing factor 1 2 2
MIRT548914 CHEK2 checkpoint kinase 2 2 4
MIRT549970 RPL7L1 ribosomal protein L7 like 1 2 4
MIRT550502 TMEM241 transmembrane protein 241 2 2
MIRT551062 MKLN1 muskelin 1 2 2
MIRT552824 XIAP X-linked inhibitor of apoptosis 2 4
MIRT553158 UBE2H ubiquitin conjugating enzyme E2 H 2 2
MIRT553843 SYNCRIP synaptotagmin binding cytoplasmic RNA interacting protein 2 2
MIRT554271 SIX4 SIX homeobox 4 2 2
MIRT555794 PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 2 2
MIRT556331 MAP2K4 mitogen-activated protein kinase kinase 4 2 2
MIRT556512 LIPA lipase A, lysosomal acid type 2 2
MIRT556706 KLHL28 kelch like family member 28 2 2
MIRT556765 KLF7 Kruppel like factor 7 2 2
MIRT557003 HPRT1 hypoxanthine phosphoribosyltransferase 1 2 2
MIRT557159 HOXA13 homeobox A13 2 2
MIRT557500 GPR27 G protein-coupled receptor 27 2 4
MIRT558115 ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 2 2
MIRT559357 ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) 2 2
MIRT560348 ZWINT ZW10 interacting kinetochore protein 2 2
MIRT561312 ZBTB43 zinc finger and BTB domain containing 43 2 2
MIRT561896 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 2
MIRT561940 MFSD9 major facilitator superfamily domain containing 9 2 2
MIRT562948 TNIP2 TNFAIP3 interacting protein 2 2 2
MIRT563304 BBS10 Bardet-Biedl syndrome 10 2 2
MIRT563418 KIF3A kinesin family member 3A 2 2
MIRT563575 KIAA1586 KIAA1586 2 2
MIRT565888 NHS NHS actin remodeling regulator 2 2
MIRT566094 RCC2 regulator of chromosome condensation 2 2 2
MIRT566409 PLAGL2 PLAG1 like zinc finger 2 2 2
MIRT567272 HSP90AA1 heat shock protein 90 alpha family class A member 1 2 2
MIRT571481 CCDC80 coiled-coil domain containing 80 2 2
MIRT572952 VDAC2 voltage dependent anion channel 2 2 2
MIRT573641 ZNF724P zinc finger protein 724 2 2
MIRT573730 KHSRP KH-type splicing regulatory protein 2 2
MIRT609101 SMIM15 small integral membrane protein 15 2 6
MIRT617949 EBNA1BP2 EBNA1 binding protein 2 2 2
MIRT618392 PRKG2 protein kinase, cGMP-dependent, type II 2 2
MIRT619640 PLEKHG7 pleckstrin homology and RhoGEF domain containing G7 2 2
MIRT623468 KDM5A lysine demethylase 5A 2 2
MIRT629158 CTCFL CCCTC-binding factor like 2 2
MIRT638534 LYRM2 LYR motif containing 2 2 2
MIRT649496 CLDN16 claudin 16 2 2
MIRT683161 MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 2 2
MIRT691673 SLC43A3 solute carrier family 43 member 3 2 2
MIRT693214 MKI67 marker of proliferation Ki-67 2 2
MIRT695347 AQP3 aquaporin 3 (Gill blood group) 2 2
MIRT701036 PCGF5 polycomb group ring finger 5 2 2
MIRT708766 RYBP RING1 and YY1 binding protein 2 2
MIRT717571 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT719299 SETD7 SET domain containing lysine methyltransferase 7 2 2
MIRT725185 SDAD1 SDA1 domain containing 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-548aq Paclitaxel 36314 NSC125973 approved resistant cell line (BAS)
hsa-miR-548aq-5p Gefitinib 123631 NSC715055 approved sensitive High Non-Small Cell Lung Cancer tissue
hsa-miR-548aq-5p Erlotinib 176870 NSC718781 approved sensitive High Non-Small Cell Lung Cancer tissue
hsa-miR-548aq-5p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-548aq-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-548aq-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-548aq-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-548aq-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)

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