miRTarBase - #MIRT098316


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pre-miRNA Information
pre-miRNA hsa-mir-4282   
Genomic Coordinates chr6: 72967687 - 72967753
Description Homo sapiens miR-4282 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4282
Sequence 40| UAAAAUUUGCAUCCAGGA |57
Evidence Experimental
Experiments SOLiD
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN32074657 13 COSMIC
COSN6331413 18 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1195771339 5 dbSNP
rs755058572 6 dbSNP
rs1245753664 11 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol REV3L   
Synonyms POLZ, REV3
Description REV3 like, DNA directed polymerase zeta catalytic subunit
Transcript NM_002912   
Expression
Putative miRNA Targets on REV3L
3'UTR of REV3L
(miRNA target sites are highlighted)		 
>REV3L|NM_002912|3'UTR
   1 ATTGTCAATATCACAGTATTACAGGTGCTATTTTTTTCAGTGCTTACCACTAAACTGTTGTGCATGGTGCTTTTTAACTT
  81 TCATCGAGTCAAGGATGTTCACTGTCTGTTATCTGAAGACTATGAAGACTTCTATGCTAACCGAATTAAAATGTACTTGT
 161 TGATCTCTGAATAGCTCACTTCTTACAATGTACAAATTCCTCATTCTGTCACCTTTTAAACATTGTTTTATAATGCAGGT
 241 GTTGGATTTGCTCCAGTATGTGTACCATCTTGTAAATTCATTTGAGTAGATCATGTTTACTTCCCAGTGGAAGGAGCACT
 321 GAAAACCTCTTAAAGAAAAAGCATTTGTGTGTTTTCCTTGAACTGTCTGTATCAAGACGTGTTACTTCGAGATATCCATT
 401 CACTTTATAATTTTGACTGCAAAATATTTTGTAAATACACTTTTTTACTTTTCAAACGAGCAAAATAATGTGCAATGATT
 481 TTTATACAAATGATTTTCAAGTTGTTTGGTATATTTCCTCTAGGTTTTGCTTGACTCAAAGTAGATCGTTATTTTGATCA
 561 AACTGTGCAAACAGTAGTACCACGTGTAGCATTTTGAAACATTATTTTTTTTTAAAAAATGCTGTCTTGCTTTAGCTATT
 641 AATGGGGCATTGTGAGGAACTGTGCAAAGACATTTTTGTTACAAACCTGTGGGCCTGTTGCAATACTTTAAAAATAAAAA
 721 ATTTTATTCCATTTGCTTGTTTTGTATAGACATTTCTATTGCTTCTAAATATACTTAAAATATTTTCTTTCCTTATGTAC
 801 TGTACAGTTAATCTTATTTGCCATCATCTTGAACACAAAATGTGTATTTAGAATATTTGTATAACTGTGTAAAATAAAAA
 881 AGGAATTATGTGGTCAGTGCATTGTTTTTTAAACTGGAAATCATTTTGTTTTAAAAGTTAATAATGGAAACCATATTAAA
 961 ATTGAATAAAATATAAAATAATATAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agGACCUACGUU--UAAAAu 5'
            |||||   ||  ||||| 
Target 5' aaCTGGA---AATCATTTTg 3'
 912 - 928 113.00 -7.20
2 
miRNA  3' aggaccuACGUUUAAaau 5'
                 ||:|||||   
Target 5' accatctTGTAAATTcat 3'
 264 - 281 111.00 -5.62
3 
miRNA  3' agGACCUACG--UU-UAAAAU-- 5'
            :||  |||  || |||||:  
Target 5' ttTTGACTGCAAAATATTTTGTA 3'
 411 - 433 108.00 -5.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31526302 30 COSMIC
COSN26633950 42 COSMIC
COSN20649198 60 COSMIC
COSN30488132 66 COSMIC
COSN26991989 92 COSMIC
COSN31587101 142 COSMIC
COSN30111739 143 COSMIC
COSN31549487 143 COSMIC
COSN30493143 154 COSMIC
COSN30541002 254 COSMIC
COSN22724811 264 COSMIC
COSN21060158 436 COSMIC
COSN31515104 438 COSMIC
COSN14948282 461 COSMIC
COSN31585019 477 COSMIC
COSN20103261 605 COSMIC
COSN2133828 719 COSMIC
COSN31538733 787 COSMIC
COSN24301521 795 COSMIC
COSN31513473 795 COSMIC
COSN31584243 807 COSMIC
COSN16209010 925 COSMIC
COSN31522257 936 COSMIC
rs465646 461 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1470653866 4 dbSNP
rs368202173 8 dbSNP
rs1208179881 10 dbSNP
rs1423889910 10 dbSNP
rs1474798237 11 dbSNP
rs1441910971 14 dbSNP
rs771515713 18 dbSNP
rs749743739 19 dbSNP
rs374319084 22 dbSNP
rs756264532 23 dbSNP
rs748177644 28 dbSNP
rs1373673055 29 dbSNP
rs370544186 30 dbSNP
rs1303046252 31 dbSNP
rs763549507 32 dbSNP
rs775502327 33 dbSNP
rs1334295279 34 dbSNP
rs1312894608 36 dbSNP
rs1436529637 37 dbSNP
rs769830340 38 dbSNP
rs1405737963 39 dbSNP
rs377518998 40 dbSNP
rs1301345708 41 dbSNP
rs1158167174 44 dbSNP
rs925219823 48 dbSNP
rs759676670 50 dbSNP
rs139031605 52 dbSNP
rs941078480 54 dbSNP
rs1248633153 64 dbSNP
rs775783723 74 dbSNP
rs953155387 78 dbSNP
rs747632196 80 dbSNP
rs1028841244 82 dbSNP
rs778769599 85 dbSNP
rs1190439164 86 dbSNP
rs780586306 86 dbSNP
rs1163575482 88 dbSNP
rs932263683 93 dbSNP
rs553876736 104 dbSNP
rs1384561127 107 dbSNP
rs1027204786 110 dbSNP
rs139435988 110 dbSNP
rs995728764 110 dbSNP
rs1452000748 119 dbSNP
rs1314298469 124 dbSNP
rs1357119405 127 dbSNP
rs905345471 128 dbSNP
rs1261054484 131 dbSNP
rs866642012 134 dbSNP
rs1203063984 135 dbSNP
rs1257823359 140 dbSNP
rs949583323 141 dbSNP
rs896559329 142 dbSNP
rs1052986267 143 dbSNP
rs531848344 145 dbSNP
rs765345451 151 dbSNP
rs749363545 163 dbSNP
rs979311826 165 dbSNP
rs1174599308 169 dbSNP
rs1403097722 176 dbSNP
rs746702656 177 dbSNP
rs913198737 179 dbSNP
rs561031648 180 dbSNP
rs1380534699 181 dbSNP
rs780372486 183 dbSNP
rs990643073 184 dbSNP
rs1390430050 185 dbSNP
rs1307592466 186 dbSNP
rs777985351 186 dbSNP
rs376178752 188 dbSNP
rs1236610117 190 dbSNP
rs1257403093 195 dbSNP
rs1323733239 197 dbSNP
rs1202514458 203 dbSNP
rs1368111279 212 dbSNP
rs1165851554 219 dbSNP
rs1178344760 223 dbSNP
rs931869899 223 dbSNP
rs1250424950 227 dbSNP
rs1422675495 238 dbSNP
rs1201387349 252 dbSNP
rs1430274029 259 dbSNP
rs921876901 260 dbSNP
rs975907303 267 dbSNP
rs1159353081 270 dbSNP
rs965909066 274 dbSNP
rs1462552633 279 dbSNP
rs1298746813 282 dbSNP
rs1421550651 283 dbSNP
rs17511602 293 dbSNP
rs1362107362 303 dbSNP
rs1303080717 312 dbSNP
rs55962943 314 dbSNP
rs776946443 315 dbSNP
rs1222573388 316 dbSNP
rs560073028 332 dbSNP
rs1269996062 338 dbSNP
rs1319468546 340 dbSNP
rs971329297 341 dbSNP
rs1251256891 348 dbSNP
rs1479916339 351 dbSNP
rs951717672 353 dbSNP
rs1264464456 356 dbSNP
rs1490282855 356 dbSNP
rs545291141 360 dbSNP
rs1197609436 361 dbSNP
rs577831612 376 dbSNP
rs187701564 378 dbSNP
rs994048459 379 dbSNP
rs1460437269 384 dbSNP
rs537626045 387 dbSNP
rs896815023 389 dbSNP
rs1404102263 394 dbSNP
rs1300906924 402 dbSNP
rs1214667056 403 dbSNP
rs1363562811 403 dbSNP
rs1294186204 406 dbSNP
rs1305226303 406 dbSNP
rs1490308756 413 dbSNP
rs779848710 413 dbSNP
rs184422031 415 dbSNP
rs889528935 419 dbSNP
rs1486290727 422 dbSNP
rs1284974812 426 dbSNP
rs1186113736 427 dbSNP
rs1050577695 437 dbSNP
rs1425615444 441 dbSNP
rs538715622 447 dbSNP
rs1344836395 455 dbSNP
rs1385712944 457 dbSNP
rs1161388325 458 dbSNP
rs932148650 458 dbSNP
rs465646 461 dbSNP
rs1040613275 469 dbSNP
rs1287902717 479 dbSNP
rs1359328820 482 dbSNP
rs896648307 486 dbSNP
rs1052494253 490 dbSNP
rs946281250 491 dbSNP
rs757717942 507 dbSNP
rs373858325 509 dbSNP
rs546493451 509 dbSNP
rs1317869685 512 dbSNP
rs1215402797 515 dbSNP
rs1259178219 516 dbSNP
rs1288362904 525 dbSNP
rs990139834 528 dbSNP
rs1184222678 532 dbSNP
rs370469739 547 dbSNP
rs1443886562 548 dbSNP
rs1181646916 549 dbSNP
rs1466751956 554 dbSNP
rs1401063289 555 dbSNP
rs1431651030 574 dbSNP
rs936114344 580 dbSNP
rs1158011144 581 dbSNP
rs533814037 583 dbSNP
rs979974172 586 dbSNP
rs1382745689 600 dbSNP
rs1451154216 603 dbSNP
rs566486255 604 dbSNP
rs11968478 607 dbSNP
rs1374588525 607 dbSNP
rs921844845 607 dbSNP
rs944522512 608 dbSNP
rs976000520 608 dbSNP
rs973077267 609 dbSNP
rs1201760730 610 dbSNP
rs1262634025 610 dbSNP
rs1424750469 610 dbSNP
rs200664035 611 dbSNP
rs199677596 612 dbSNP
rs201523626 613 dbSNP
rs1176355914 614 dbSNP
rs1405375885 614 dbSNP
rs3049440 614 dbSNP
rs397725475 614 dbSNP
rs869055083 614 dbSNP
rs961288299 614 dbSNP
rs750347627 615 dbSNP
rs781535086 615 dbSNP
rs920386153 615 dbSNP
rs979729963 620 dbSNP
rs969733924 625 dbSNP
rs1259062955 628 dbSNP
rs1278107921 633 dbSNP
rs1347739679 634 dbSNP
rs1023801231 638 dbSNP
rs1282869632 639 dbSNP
rs571814218 643 dbSNP
rs1321585065 644 dbSNP
rs1017039321 646 dbSNP
rs1013798398 648 dbSNP
rs1275047400 658 dbSNP
rs773427233 658 dbSNP
rs1005198643 659 dbSNP
rs1203602587 665 dbSNP
rs772702595 667 dbSNP
rs1031603554 669 dbSNP
rs559874994 671 dbSNP
rs1428077973 678 dbSNP
rs1264571611 681 dbSNP
rs1221270060 682 dbSNP
rs999730107 683 dbSNP
rs1169090011 687 dbSNP
rs889572207 689 dbSNP
rs760950938 691 dbSNP
rs770188626 692 dbSNP
rs903930923 695 dbSNP
rs1327413104 697 dbSNP
rs1367915349 701 dbSNP
rs1405931194 702 dbSNP
rs1028027229 709 dbSNP
rs766893507 711 dbSNP
rs1278589756 719 dbSNP
rs1270807157 721 dbSNP
rs17540325 722 dbSNP
rs748536710 722 dbSNP
rs1361330942 723 dbSNP
rs900512574 724 dbSNP
rs1267758578 727 dbSNP
rs1449474519 729 dbSNP
rs373019591 729 dbSNP
rs1242243645 730 dbSNP
rs142260933 733 dbSNP
rs1040286742 734 dbSNP
rs902028085 735 dbSNP
rs1040490951 736 dbSNP
rs1317743720 739 dbSNP
rs1396633074 743 dbSNP
rs1163286943 744 dbSNP
rs1408618201 744 dbSNP
rs946309286 746 dbSNP
rs1363983757 753 dbSNP
rs892027591 753 dbSNP
rs1048007689 757 dbSNP
rs561085973 758 dbSNP
rs1428639134 778 dbSNP
rs936007073 780 dbSNP
rs1295328865 783 dbSNP
rs1384882649 784 dbSNP
rs1246496923 786 dbSNP
rs1290803138 786 dbSNP
rs1353935000 789 dbSNP
rs927398843 796 dbSNP
rs1445983940 797 dbSNP
rs920341552 802 dbSNP
rs980192762 803 dbSNP
rs969660064 804 dbSNP
rs1445731687 805 dbSNP
rs916925078 807 dbSNP
rs1367105453 808 dbSNP
rs992396560 811 dbSNP
rs1401555997 813 dbSNP
rs191290763 818 dbSNP
rs950087288 823 dbSNP
rs961226907 829 dbSNP
rs536070989 830 dbSNP
rs527732661 834 dbSNP
rs1384512881 836 dbSNP
rs1000102675 842 dbSNP
rs1338749655 843 dbSNP
rs1006678376 845 dbSNP
rs560135796 851 dbSNP
rs775904739 857 dbSNP
rs1022356288 859 dbSNP
rs996276555 861 dbSNP
rs1279829201 862 dbSNP
rs754433444 865 dbSNP
rs1206324042 866 dbSNP
rs900480006 867 dbSNP
rs1460592805 869 dbSNP
rs749902177 871 dbSNP
rs56213863 874 dbSNP
rs1258477190 877 dbSNP
rs1008927496 882 dbSNP
rs1421315238 882 dbSNP
rs1197277464 883 dbSNP
rs972575832 883 dbSNP
rs961620780 901 dbSNP
rs545037625 908 dbSNP
rs187253671 909 dbSNP
rs1245391407 914 dbSNP
rs1469295487 915 dbSNP
rs1061388 925 dbSNP
rs1392968505 928 dbSNP
rs764882820 928 dbSNP
rs1329260422 933 dbSNP
rs1226210671 934 dbSNP
rs1027911275 937 dbSNP
rs1323626590 938 dbSNP
rs369932589 938 dbSNP
rs1312996549 941 dbSNP
rs900906434 941 dbSNP
rs1481890626 945 dbSNP
rs1452197539 946 dbSNP
rs549543737 947 dbSNP
rs182510661 950 dbSNP
rs1482245976 953 dbSNP
rs1281301530 966 dbSNP
rs992898293 974 dbSNP
rs934385189 978 dbSNP
rs1408531544 981 dbSNP
rs1375896551 982 dbSNP
rs1463488033 982 dbSNP
rs1298627696 983 dbSNP
rs573873657 983 dbSNP
rs1019553530 984 dbSNP
rs1304647635 984 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000368802.3 | 3UTR | CAAUACUUUAAAAAUAAAAAAUUUUAUUCCAU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
280 hsa-miR-4282 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT057628 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT060732 RPS3 ribosomal protein S3 2 2
MIRT063371 ETNK1 ethanolamine kinase 1 2 2
MIRT066257 LRIG3 leucine rich repeats and immunoglobulin like domains 3 2 4
MIRT070774 HIF1A hypoxia inducible factor 1 alpha subunit 2 2
MIRT070871 EIF2S1 eukaryotic translation initiation factor 2 subunit alpha 2 4
MIRT078056 PCTP phosphatidylcholine transfer protein 2 2
MIRT078408 DCAF7 DDB1 and CUL4 associated factor 7 2 4
MIRT084059 PPP1R3D protein phosphatase 1 regulatory subunit 3D 2 2
MIRT093537 GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 2 6
MIRT096072 SFXN1 sideroflexin 1 2 2
MIRT098316 REV3L REV3 like, DNA directed polymerase zeta catalytic subunit 2 2
MIRT100493 UHRF1BP1 UHRF1 binding protein 1 2 2
MIRT102254 HBP1 HMG-box transcription factor 1 2 4
MIRT105318 VPS37A VPS37A, ESCRT-I subunit 2 2
MIRT114143 MZT1 mitotic spindle organizing protein 1 2 4
MIRT114873 DICER1 dicer 1, ribonuclease III 2 2
MIRT134683 PNRC2 proline rich nuclear receptor coactivator 2 2 2
MIRT137640 RCOR1 REST corepressor 1 2 2
MIRT155449 CCNT2 cyclin T2 2 4
MIRT165656 DCTN4 dynactin subunit 4 2 2
MIRT177570 CSTF2T cleavage stimulation factor subunit 2 tau variant 2 4
MIRT188514 E2F7 E2F transcription factor 7 2 10
MIRT193019 TMOD3 tropomodulin 3 2 4
MIRT195823 GADD45A growth arrest and DNA damage inducible alpha 2 2
MIRT195885 DEPDC1 DEP domain containing 1 2 6
MIRT206029 NUP50 nucleoporin 50 2 6
MIRT212148 CLCN3 chloride voltage-gated channel 3 2 2
MIRT213999 DCP2 decapping mRNA 2 2 2
MIRT214650 HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 2 2
MIRT221568 CBX3 chromobox 3 2 2
MIRT224544 ZNF623 zinc finger protein 623 2 2
MIRT227654 SET SET nuclear proto-oncogene 2 2
MIRT229992 CHIC1 cysteine rich hydrophobic domain 1 2 2
MIRT238968 QKI QKI, KH domain containing RNA binding 2 2
MIRT239825 ACTB actin beta 2 2
MIRT241084 ZXDA zinc finger, X-linked, duplicated A 2 4
MIRT244852 ZBTB5 zinc finger and BTB domain containing 5 2 2
MIRT264534 TARDBP TAR DNA binding protein 2 2
MIRT271438 SKI SKI proto-oncogene 2 2
MIRT271597 ENAH ENAH, actin regulator 2 2
MIRT294332 ZNF264 zinc finger protein 264 2 2
MIRT296341 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT301715 TEF TEF, PAR bZIP transcription factor 2 2
MIRT308549 ZNF654 zinc finger protein 654 2 2
MIRT313866 DEPDC1B DEP domain containing 1B 2 2
MIRT315529 MARCKS myristoylated alanine rich protein kinase C substrate 2 2
MIRT321066 RABGEF1 RAB guanine nucleotide exchange factor 1 2 2
MIRT343777 NUTF2 nuclear transport factor 2 2 2
MIRT359109 MAP1B microtubule associated protein 1B 2 2
MIRT397393 GOLGA3 golgin A3 2 4
MIRT400822 CPEB2 cytoplasmic polyadenylation element binding protein 2 2 2
MIRT442171 DSEL dermatan sulfate epimerase-like 2 2
MIRT442777 JAG1 jagged 1 2 2
MIRT442862 SCARF1 scavenger receptor class F member 1 2 4
MIRT442919 PCBD2 pterin-4 alpha-carbinolamine dehydratase 2 2 2
MIRT444567 TRA2B transformer 2 beta homolog 2 2
MIRT444718 CMSS1 cms1 ribosomal small subunit homolog (yeast) 2 2
MIRT445018 RBMS3 RNA binding motif single stranded interacting protein 3 2 2
MIRT445853 LRRC1 leucine rich repeat containing 1 2 2
MIRT446242 HELZ helicase with zinc finger 2 2
MIRT446542 GOLGA8B golgin A8 family member B 2 2
MIRT446643 SPTY2D1 SPT2 chromatin protein domain containing 1 2 2
MIRT446948 ZMAT3 zinc finger matrin-type 3 2 4
MIRT447061 KCNAB1 potassium voltage-gated channel subfamily A member regulatory beta subunit 1 2 2
MIRT447327 ZSCAN21 zinc finger and SCAN domain containing 21 2 2
MIRT447995 CDX1 caudal type homeobox 1 2 2
MIRT448543 RHEBP1 RHEB pseudogene 1 2 6
MIRT448752 HINT1 histidine triad nucleotide binding protein 1 2 2
MIRT448772 GOLGA8A golgin A8 family member A 2 2
MIRT449342 WDR26 WD repeat domain 26 2 2
MIRT450011 SLC16A6 solute carrier family 16 member 6 2 4
MIRT450229 PCNX pecanex homolog 1 2 2
MIRT450340 MRPL17 mitochondrial ribosomal protein L17 2 4
MIRT450381 MSI2 musashi RNA binding protein 2 2 2
MIRT450759 PGGT1B protein geranylgeranyltransferase type I subunit beta 2 2
MIRT450809 NRCAM neuronal cell adhesion molecule 2 2
MIRT450947 ATAD2 ATPase family, AAA domain containing 2 2 2
MIRT459095 CCPG1 cell cycle progression 1 2 2
MIRT462428 TWISTNB TWIST neighbor 2 2
MIRT465200 TROVE2 TROVE domain family member 2 2 4
MIRT467382 SON SON DNA binding protein 2 4
MIRT468546 SERP1 stress associated endoplasmic reticulum protein 1 2 2
MIRT471506 PDE4D phosphodiesterase 4D 2 2
MIRT471981 NR3C1 nuclear receptor subfamily 3 group C member 1 2 2
MIRT474478 KLHL11 kelch like family member 11 2 8
MIRT475011 KANSL1 KAT8 regulatory NSL complex subunit 1 2 8
MIRT480341 C5orf51 chromosome 5 open reading frame 51 2 2
MIRT482696 TEX9 testis expressed 9 2 6
MIRT483462 YTHDF1 YTH N6-methyladenosine RNA binding protein 1 2 6
MIRT485623 FAM217B family with sequence similarity 217 member B 2 2
MIRT485714 CASP16 caspase 16, pseudogene 2 8
MIRT486279 SEC23A Sec23 homolog A, coat complex II component 2 2
MIRT491000 PEBP1 phosphatidylethanolamine binding protein 1 2 4
MIRT492594 PPIL4 peptidylprolyl isomerase like 4 2 2
MIRT493365 KIF5B kinesin family member 5B 2 2
MIRT494316 CDKN1B cyclin dependent kinase inhibitor 1B 2 2
MIRT495208 EDN3 endothelin 3 2 2
MIRT497011 TCF15 transcription factor 15 2 2
MIRT498512 FRK fyn related Src family tyrosine kinase 2 2
MIRT498778 PARP15 poly(ADP-ribose) polymerase family member 15 2 2
MIRT501045 SMG1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 2 6
MIRT502939 CDC37L1 cell division cycle 37 like 1 2 8
MIRT504806 VHL von Hippel-Lindau tumor suppressor 2 6
MIRT505656 SHMT1 serine hydroxymethyltransferase 1 2 6
MIRT505964 RAB5C RAB5C, member RAS oncogene family 2 6
MIRT506322 OTUD4 OTU deubiquitinase 4 2 4
MIRT506803 KLHL15 kelch like family member 15 2 6
MIRT506917 KBTBD8 kelch repeat and BTB domain containing 8 2 4
MIRT507400 EMC7 ER membrane protein complex subunit 7 2 8
MIRT507471 EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 2 6
MIRT508058 ATP13A3 ATPase 13A3 2 4
MIRT508135 AMD1 adenosylmethionine decarboxylase 1 2 2
MIRT509895 RPS23 ribosomal protein S23 2 4
MIRT510881 RAN RAN, member RAS oncogene family 2 8
MIRT513766 PEX5L peroxisomal biogenesis factor 5 like 2 4
MIRT516898 COPS8 COP9 signalosome subunit 8 2 2
MIRT518703 TIMD4 T-cell immunoglobulin and mucin domain containing 4 2 4
MIRT520429 TTPAL alpha tocopherol transfer protein like 2 6
MIRT521843 PNISR PNN interacting serine and arginine rich protein 2 4
MIRT522116 NUDT3 nudix hydrolase 3 2 4
MIRT525467 TMPRSS12 transmembrane protease, serine 12 2 2
MIRT525583 MTRNR2L7 MT-RNR2-like 7 2 2
MIRT525906 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 2 2
MIRT526072 C11orf54 chromosome 11 open reading frame 54 2 2
MIRT526232 MTRNR2L5 MT-RNR2-like 5 2 4
MIRT526455 FAM71F2 family with sequence similarity 71 member F2 2 4
MIRT526515 POU5F1B POU class 5 homeobox 1B 2 2
MIRT528032 FEZ2 fasciculation and elongation protein zeta 2 2 2
MIRT528422 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT528995 ISLR2 immunoglobulin superfamily containing leucine rich repeat 2 2 4
MIRT529311 ATRNL1 attractin like 1 2 2
MIRT529376 SKP1 S-phase kinase associated protein 1 2 4
MIRT530015 SRRM1 serine and arginine repetitive matrix 1 2 2
MIRT530089 FMN2 formin 2 2 2
MIRT530942 ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 2 2
MIRT531229 HIST1H2BD histone cluster 1 H2B family member d 2 2
MIRT533088 YTHDF3 YTH N6-methyladenosine RNA binding protein 3 2 2
MIRT533299 USP46 ubiquitin specific peptidase 46 2 2
MIRT533318 UNKL unkempt family like zinc finger 2 2
MIRT533721 TMEM30A transmembrane protein 30A 2 2
MIRT534096 AZF1 azoospermia factor 1 2 2
MIRT534188 SLC7A11 solute carrier family 7 member 11 2 2
MIRT534493 SAR1B secretion associated Ras related GTPase 1B 2 2
MIRT536077 MBOAT2 membrane bound O-acyltransferase domain containing 2 2 2
MIRT536242 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 2
MIRT537524 FAM104A family with sequence similarity 104 member A 2 2
MIRT538088 DGKH diacylglycerol kinase eta 2 2
MIRT538475 CNBP CCHC-type zinc finger nucleic acid binding protein 2 2
MIRT538853 BTG1 BTG anti-proliferation factor 1 2 4
MIRT539075 GDNF glial cell derived neurotrophic factor 2 2
MIRT539480 ACVR2B activin A receptor type 2B 2 4
MIRT540210 ARHGAP18 Rho GTPase activating protein 18 2 2
MIRT541940 TSPAN2 tetraspanin 2 2 2
MIRT543812 COCH cochlin 2 2
MIRT545120 PDZRN4 PDZ domain containing ring finger 4 2 2
MIRT545571 GIMAP4 GTPase, IMAP family member 4 2 2
MIRT545989 XKR4 XK related 4 2 2
MIRT547213 PANK3 pantothenate kinase 3 2 4
MIRT547740 KIAA1468 KIAA1468 2 2
MIRT548022 GRB2 growth factor receptor bound protein 2 2 4
MIRT548032 GOLIM4 golgi integral membrane protein 4 2 2
MIRT548102 GFPT1 glutamine--fructose-6-phosphate transaminase 1 2 4
MIRT548217 FKBP1A FK506 binding protein 1A 2 2
MIRT548588 DDX3X DEAD-box helicase 3, X-linked 2 4
MIRT548953 CDC27 cell division cycle 27 2 2
MIRT549072 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT550368 INCENP inner centromere protein 2 6
MIRT550546 MYZAP myocardial zonula adherens protein 2 2
MIRT551491 TMEM192 transmembrane protein 192 2 4
MIRT553078 UEVLD UEV and lactate/malate dehyrogenase domains 2 2
MIRT554104 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT555127 PTPRG protein tyrosine phosphatase, receptor type G 2 2
MIRT555477 POC1B-GALNT4 POC1B-GALNT4 readthrough 2 2
MIRT555978 NPTN neuroplastin 2 2
MIRT557011 HPRT1 hypoxanthine phosphoribosyltransferase 1 2 2
MIRT557706 GALNT4 polypeptide N-acetylgalactosaminyltransferase 4 2 2
MIRT558333 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 4
MIRT558488 DBN1 drebrin 1 2 2
MIRT559942 ZNF567 zinc finger protein 567 2 2
MIRT561127 ATP2B1 ATPase plasma membrane Ca2+ transporting 1 2 2
MIRT561791 PAWR pro-apoptotic WT1 regulator 2 2
MIRT562438 EEF2 eukaryotic translation elongation factor 2 2 2
MIRT563102 PABPC4L poly(A) binding protein cytoplasmic 4 like 2 2
MIRT563212 ZNF813 zinc finger protein 813 2 2
MIRT563426 KIF3A kinesin family member 3A 2 2
MIRT563473 SPIN4 spindlin family member 4 2 2
MIRT564015 HSPA4 heat shock protein family A (Hsp70) member 4 2 4
MIRT564117 ZYG11B zyg-11 family member B, cell cycle regulator 2 2
MIRT564223 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT564503 CACNG1 calcium voltage-gated channel auxiliary subunit gamma 1 2 2
MIRT564515 DUSP3 dual specificity phosphatase 3 2 2
MIRT564811 ZBTB21 zinc finger and BTB domain containing 21 2 2
MIRT565265 TPD52 tumor protein D52 2 2
MIRT566012 RHOB ras homolog family member B 2 2
MIRT566216 PTMA prothymosin, alpha 2 2
MIRT566638 NFYA nuclear transcription factor Y subunit alpha 2 2
MIRT566821 MAPK8 mitogen-activated protein kinase 8 2 2
MIRT566948 LEPROT leptin receptor overlapping transcript 2 2
MIRT567290 HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 2 2
MIRT567895 CSTF2 cleavage stimulation factor subunit 2 2 2
MIRT568731 MTRNR2L3 MT-RNR2-like 3 2 2
MIRT571263 ZNF239 zinc finger protein 239 2 2
MIRT572593 EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 2 2
MIRT573827 TGOLN2 trans-golgi network protein 2 2 2
MIRT576391 Fhl2 four and a half LIM domains 2 2 2
MIRT609901 SMS spermine synthase 2 2
MIRT613710 ELMSAN1 ELM2 and Myb/SANT domain containing 1 2 2
MIRT614406 ADAT1 adenosine deaminase, tRNA specific 1 2 2
MIRT615042 DCX doublecortin 2 2
MIRT617514 C5orf45 MRN complex interacting protein 2 2
MIRT619476 PRDM10 PR/SET domain 10 2 2
MIRT620349 TLN1 talin 1 2 2
MIRT620910 PLA2G7 phospholipase A2 group VII 2 2
MIRT622131 SP4 Sp4 transcription factor 2 2
MIRT622955 OTUD7B OTU deubiquitinase 7B 2 2
MIRT623351 MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 2 2
MIRT623619 INTU inturned planar cell polarity protein 2 2
MIRT624409 CCDC171 coiled-coil domain containing 171 2 2
MIRT625171 CCS copper chaperone for superoxide dismutase 2 2
MIRT625685 RPP40 ribonuclease P/MRP subunit p40 2 2
MIRT625875 ALDH18A1 aldehyde dehydrogenase 18 family member A1 2 2
MIRT626002 FAM107A family with sequence similarity 107 member A 2 2
MIRT626872 HRH4 histamine receptor H4 2 4
MIRT628220 FKBP9 FK506 binding protein 9 2 2
MIRT628265 DIO2 iodothyronine deiodinase 2 2 2
MIRT628402 C8orf37 chromosome 8 open reading frame 37 2 2
MIRT630564 C3orf36 chromosome 3 open reading frame 36 2 4
MIRT631577 RASSF9 Ras association domain family member 9 2 2
MIRT635730 CCDC58 coiled-coil domain containing 58 2 2
MIRT636224 SLC8A1 solute carrier family 8 member A1 2 2
MIRT636613 CLIC5 chloride intracellular channel 5 2 2
MIRT638899 CDK9 cyclin dependent kinase 9 2 2
MIRT640167 ATXN7L1 ataxin 7 like 1 2 2
MIRT642070 GTDC1 glycosyltransferase like domain containing 1 2 2
MIRT643034 CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 2 2
MIRT644572 SPOP speckle type BTB/POZ protein 2 2
MIRT644954 IFNB1 interferon beta 1 2 2
MIRT645948 TTF2 transcription termination factor 2 2 2
MIRT646440 XRCC2 X-ray repair cross complementing 2 2 2
MIRT647896 EPN2 epsin 2 2 2
MIRT648276 ZNF582 zinc finger protein 582 2 2
MIRT649381 NEDD1 neural precursor cell expressed, developmentally down-regulated 1 2 2
MIRT650254 CD68 CD68 molecule 2 2
MIRT650333 ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B) 2 2
MIRT651707 VMP1 vacuole membrane protein 1 2 2
MIRT651774 VASP vasodilator stimulated phosphoprotein 2 2
MIRT653144 SRPK2 SRSF protein kinase 2 2 2
MIRT654112 RPS6KA5 ribosomal protein S6 kinase A5 2 2
MIRT654161 RORB RAR related orphan receptor B 2 2
MIRT655716 MLF2 myeloid leukemia factor 2 2 2
MIRT657476 HDAC4 histone deacetylase 4 2 2
MIRT658095 FOXO1 forkhead box O1 2 2
MIRT658860 DTX3L deltex E3 ubiquitin ligase 3L 2 2
MIRT658988 DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 2 2
MIRT660767 ALDH6A1 aldehyde dehydrogenase 6 family member A1 2 2
MIRT661622 C2orf15 chromosome 2 open reading frame 15 2 2
MIRT661694 TFDP2 transcription factor Dp-2 2 2
MIRT662208 PLA2G4E phospholipase A2 group IVE 2 2
MIRT662443 RALGAPA1 Ral GTPase activating protein catalytic alpha subunit 1 2 2
MIRT664422 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2 2
MIRT687505 NECAB1 N-terminal EF-hand calcium binding protein 1 2 2
MIRT689910 SOD2 superoxide dismutase 2 2 2
MIRT690781 PLA2G2C phospholipase A2 group IIC 2 2
MIRT698488 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT699685 SFMBT2 Scm like with four mbt domains 2 2 2
MIRT700926 PDS5A PDS5 cohesin associated factor A 2 2
MIRT702258 LMNB1 lamin B1 2 2
MIRT703166 GPR137C G protein-coupled receptor 137C 2 2
MIRT703242 GNS glucosamine (N-acetyl)-6-sulfatase 2 2
MIRT704737 CENPQ centromere protein Q 2 2
MIRT707310 GLRX2 glutaredoxin 2 2 2
MIRT710021 KCNQ5 potassium voltage-gated channel subfamily Q member 5 2 2
MIRT712212 SCOC short coiled-coil protein 2 2
MIRT714742 SETBP1 SET binding protein 1 2 2
MIRT718268 ZNF749 zinc finger protein 749 2 2
MIRT720553 DYRK4 dual specificity tyrosine phosphorylation regulated kinase 4 2 2
MIRT722248 RBM41 RNA binding motif protein 41 2 2
MIRT723767 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT723977 KIAA0146 scaffolding protein involved in DNA repair 1 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4282 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4282 Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-4282 Neoadjuvant chemotherapy sensitive tissue (breast cancer)

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